PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 14519336-6 2003 Homologs of Std (Na(+)- and Cl(-)-dependent ion transporter), HSPG (a mammalian basement membrane-specific heparin sulphate core protein precursor) and PntB (pyridine nucleotide transhydrogenase) were also up-regulated, but to a much lower extent. heparin sulphate 107-123 syndecan 2 Homo sapiens 62-66 12578541-3 2003 Here we report the development of a stable cell line, termed DB1, that was generated by transfecting cDNA encoding full-length human CTGF into Chinese hamster ovary cells that were mutant for heparin sulphate and chondroitin sulphate. heparin sulphate 192-208 vascular endothelial zinc finger 1 Homo sapiens 61-64 9918507-0 1998 The V3 region of gp120 is responsible for anti-HIV-1 activity of heparin sulphate. heparin sulphate 65-81 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 17-22 9918507-4 1998 It has been concluded that the inhibitory effect of heparin sulphate on the infection of CD4+ lymphocytes by recombinant HIV-1 clones is mediated mainly by the V3 region of gp120. heparin sulphate 52-68 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 173-178 8379940-5 1993 The findings suggest that, since 99% of the EC-SOD in the human body exists in the extravascular space of tissue, EC-SOD is primarily synthesized in tissues and secreted as homotetrameric native EC-SOD C. This tissue EC-SOD C should exist almost completely sequestered by heparin sulphate proteoglycans. heparin sulphate 272-288 superoxide dismutase 3 Homo sapiens 114-120 9398056-6 1997 RA stimulated the association of t-PA with the external cell membrane surface, which could be inhibited by heparin sulphate but not by mannose sugars or chelators of divalent cations, consistent with a role for amphoterin. heparin sulphate 107-123 plasminogen activator, tissue type Homo sapiens 33-37 8645351-19 1996 Thus cell surface heparin sulphate may facilitate intracellular lipid acquisition by providing a stabilizing bridge with the lipoproteins and enhance uptake through receptor-mediated processes such as LRP. heparin sulphate 18-34 LDL receptor related protein 1 Homo sapiens 201-204 9112630-8 1996 These heparin binding sites of TFPI will play an important role for the association with endothelial cells, interacting with heparin sulphate on the surface. heparin sulphate 125-141 tissue factor pathway inhibitor Homo sapiens 31-35 8068301-17 1994 SAP"s tendency to self-aggregation is abolished after its binding to heparin or heparin sulphate. heparin sulphate 80-96 amyloid P component, serum Homo sapiens 0-3 8379940-5 1993 The findings suggest that, since 99% of the EC-SOD in the human body exists in the extravascular space of tissue, EC-SOD is primarily synthesized in tissues and secreted as homotetrameric native EC-SOD C. This tissue EC-SOD C should exist almost completely sequestered by heparin sulphate proteoglycans. heparin sulphate 272-288 superoxide dismutase 3 Homo sapiens 114-120 8379940-5 1993 The findings suggest that, since 99% of the EC-SOD in the human body exists in the extravascular space of tissue, EC-SOD is primarily synthesized in tissues and secreted as homotetrameric native EC-SOD C. This tissue EC-SOD C should exist almost completely sequestered by heparin sulphate proteoglycans. heparin sulphate 272-288 superoxide dismutase 3 Homo sapiens 114-120 2529852-4 1989 Differences were also observed in the maximal acceleration of the antithrombin III-Factor Xa interaction: 1.2 x 10(9) M-1.min-1 at 0.2 microM-heparin sulphate compared with 2.2 x 10(9) M-1.min-1 at 0.04 microM-heparin. heparin sulphate 142-158 serpin family C member 1 Homo sapiens 66-82 2529852-4 1989 Differences were also observed in the maximal acceleration of the antithrombin III-Factor Xa interaction: 1.2 x 10(9) M-1.min-1 at 0.2 microM-heparin sulphate compared with 2.2 x 10(9) M-1.min-1 at 0.04 microM-heparin. heparin sulphate 142-158 coagulation factor X Homo sapiens 83-92 30408744-6 2018 RESOURCE DETAILS: Mucopolysaccharidosis IIIB (MPSIII, Sanfilippo syndrome type B) is a pediatric neurodegenerative disorder caused by a deficiency in NAGLU, an enzyme required for lysosomal degradation of heparin sulphate (HS). heparin sulphate 205-221 N-acetyl-alpha-glucosaminidase Homo sapiens 150-155 27377666-3 2016 These cross-bridges were significantly less abundant in the heparin sulphate deficient Hspg2 exon 3 null mouse IVD than in wild type. heparin sulphate 60-76 perlecan (heparan sulfate proteoglycan 2) Mus musculus 87-92 26459242-10 2015 The glycosaminoglycan biosynthesis-heparin sulphate/heparin pathway is significantly enriched in the TOP2B gene ontology analysis, suggesting changes in this pathway in the absence of TOP2B may cause the axon guidance faults. heparin sulphate 35-51 DNA topoisomerase II beta Homo sapiens 101-106