PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
8250928-1	1993	Two serine proteinases capable of digesting cytochrome P4502E1 (CYP2E1) have been purified from sodium cholate solubilized rat liver microsomal membranes.	Sodium Cholate	96-110	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	44-62
7744765-7	1995	ApoAI-(1-192) lysed dimyristoyl phosphatidylcholine liposomes slowly compared with apoAI but did form rHDL complexes with palmitoyloleoyl phosphatidylcholine or dipalmitoyl phosphatidylcholine when prepared by the sodium cholate dialysis method.	Sodium Cholate	214-228	apolipoprotein A1	Homo sapiens	0-5
8192665-1	1994	It has been reported that sodium cholate can separate the catalytic component of carnitine palmitoyltransferase-I (CPT-I) from a putative malonyl-CoA-binding regulatory protein capable of conferring sensitivity to malonyl-CoA on CPT-II.	Sodium Cholate	26-40	carnitine palmitoyltransferase 1B	Rattus norvegicus	81-113
8192665-1	1994	It has been reported that sodium cholate can separate the catalytic component of carnitine palmitoyltransferase-I (CPT-I) from a putative malonyl-CoA-binding regulatory protein capable of conferring sensitivity to malonyl-CoA on CPT-II.	Sodium Cholate	26-40	carnitine palmitoyltransferase 1B	Rattus norvegicus	115-120
8192665-1	1994	It has been reported that sodium cholate can separate the catalytic component of carnitine palmitoyltransferase-I (CPT-I) from a putative malonyl-CoA-binding regulatory protein capable of conferring sensitivity to malonyl-CoA on CPT-II.	Sodium Cholate	26-40	carnitine palmitoyltransferase 2	Rattus norvegicus	229-235
8089930-2	1994	The in vitro MAO-B inhibition by IFO was time-independent, non-competitive and tight-binding; and furthermore, in the presence of sodium cholate its inhibition was not tight-binding and was reversible.	Sodium Cholate	130-144	monoamine oxidase B	Mus musculus	13-18
8117745-1	1994	The aim of this study was to assess whether diets enriched in cholesterol, sodium cholate and drugs known to modify liver cholesterol biosynthesis can modulate hepatic lipase (H-TGL) expression and activity in vivo.	Sodium Cholate	75-89	lipase C, hepatic type	Rattus norvegicus	160-174
8117105-7	1994	Human P450 1A2 was solubilized using high concentrations of sodium cholate and Triton N-101 and could be purified to near homogeneity in high yield in two steps.	Sodium Cholate	60-74	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	6-10
9068888-5	1997	PLA suspensions stabilized by sodium cholate (PLA-Ch) interact with thrombin, factor V and calcium ions.	Sodium Cholate	30-44	coagulation factor II	Rattus norvegicus	68-76
8831950-0	1996	Purification of fibroblast growth factor-2 from human placenta using tri(n-butyl)phosphate and sodium cholate.	Sodium Cholate	95-109	fibroblast growth factor 2	Homo sapiens	16-42
7510517-9	1994	Tyrosine phosphorylated p36 required SDS buffers for extraction due to a loss of the tyrosine phosphate group under other solubilization conditions using Triton X-100 or sodium cholate.	Sodium Cholate	170-184	annexin A2	Bos taurus	24-27
8174752-2	1994	Glycerolphosphate acyltransferase (GPAT) was solubilized from the rat liver mitochondrial membranes using sodium cholate.	Sodium Cholate	106-120	glycerol-3-phosphate acyltransferase, mitochondrial	Rattus norvegicus	0-33
8174752-2	1994	Glycerolphosphate acyltransferase (GPAT) was solubilized from the rat liver mitochondrial membranes using sodium cholate.	Sodium Cholate	106-120	glycerol-3-phosphate acyltransferase, mitochondrial	Rattus norvegicus	35-39
8250928-1	1993	Two serine proteinases capable of digesting cytochrome P4502E1 (CYP2E1) have been purified from sodium cholate solubilized rat liver microsomal membranes.	Sodium Cholate	96-110	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	64-70
8240357-6	1993	Furthermore, testicular cytochrome b 5 did not increase the 17 alpha-hydroxylase activity, and the activity was largely inhibited by the addition of sodium cholate, Emulgen 913 and testicular lipid.	Sodium Cholate	149-163	cytochrome b5 type A	Sus scrofa	24-38
1402914-1	1992	5-Hydroxytryptamine3 (5-HT3) receptor-type binding sites were solubilised from NG108-15 mouse neuroblastoma x rat glioma hybrid cells using five different detergents [n-octyl-beta-D-glucoside, Triton X-100, 3-[3-(cholamidopropyl)dimethylammonio]-1-propanesulphonate (CHAPS), sodium cholate, and deoxycholate] and the solubilisation efficiencies compared.	Sodium Cholate	275-289	5-hydroxytryptamine (serotonin) receptor 3A	Mus musculus	0-28
8223583-10	1993	Treatment of the sigma 1 heterodimer with 1% sodium cholate, followed by gel filtration or anion-exchange chromatography in the presence of 1% sodium cholate, effectively separated rac1 p21 from rho GDI.	Sodium Cholate	45-59	Rac family small GTPase 1	Homo sapiens	181-185
8223583-10	1993	Treatment of the sigma 1 heterodimer with 1% sodium cholate, followed by gel filtration or anion-exchange chromatography in the presence of 1% sodium cholate, effectively separated rac1 p21 from rho GDI.	Sodium Cholate	45-59	H3 histone pseudogene 16	Homo sapiens	186-189
8223583-10	1993	Treatment of the sigma 1 heterodimer with 1% sodium cholate, followed by gel filtration or anion-exchange chromatography in the presence of 1% sodium cholate, effectively separated rac1 p21 from rho GDI.	Sodium Cholate	45-59	Rho GDP dissociation inhibitor alpha	Homo sapiens	195-202
8223583-10	1993	Treatment of the sigma 1 heterodimer with 1% sodium cholate, followed by gel filtration or anion-exchange chromatography in the presence of 1% sodium cholate, effectively separated rac1 p21 from rho GDI.	Sodium Cholate	143-157	Rac family small GTPase 1	Homo sapiens	181-185
8223583-10	1993	Treatment of the sigma 1 heterodimer with 1% sodium cholate, followed by gel filtration or anion-exchange chromatography in the presence of 1% sodium cholate, effectively separated rac1 p21 from rho GDI.	Sodium Cholate	143-157	H3 histone pseudogene 16	Homo sapiens	186-189
8223583-10	1993	Treatment of the sigma 1 heterodimer with 1% sodium cholate, followed by gel filtration or anion-exchange chromatography in the presence of 1% sodium cholate, effectively separated rac1 p21 from rho GDI.	Sodium Cholate	143-157	Rho GDP dissociation inhibitor alpha	Homo sapiens	195-202
8234011-1	1993	Intact calcitonin gene-related peptide (CGRP) receptors were solubilized from porcine neural membranes using sodium cholate: potassium buffer.	Sodium Cholate	109-123	calcitonin related polypeptide alpha	Homo sapiens	40-44
8316043-2	1993	The long-chain phosphatidylcholine/sodium cholate aqueous system as substrate for human pancreatic phospholipase A2 (PLA2) was investigated.	Sodium Cholate	35-49	phospholipase A2 group IB	Homo sapiens	99-115
8316043-2	1993	The long-chain phosphatidylcholine/sodium cholate aqueous system as substrate for human pancreatic phospholipase A2 (PLA2) was investigated.	Sodium Cholate	35-49	phospholipase A2 group IB	Homo sapiens	117-121
21043750-2	1993	In order to clarify the presence of the ram protein (ram p25) in human platelets, we tried to purify ram p25 from the sodium cholate extract of human platelet membranes by a combination of DEAE-Sephacel, Sephacryl S300HR, hydroxyapatite HCA-100S and DEAE-Toyopearl 650(S) column chromatographies.	Sodium Cholate	118-132	tubulin polymerization promoting protein	Homo sapiens	105-108
1445946-1	1992	A low M(r) GTP-binding protein with a M(r) of 26,000 has been purified from a sodium cholate extract of human platelet membranes by using an antibody raised against a synthetic peptide of c25KG, which was previously purified from human platelet cytosol (Nagata, N., et al.	Sodium Cholate	78-92	RAB27B, member RAS oncogene family	Homo sapiens	188-193
8449936-8	1993	In addition, the recombinant enzymes exhibited a number of the unique physical properties associated with FMO 1B1, including stability to elevated temperature and activation by sodium cholate and magnesium chloride.	Sodium Cholate	177-191	dimethylaniline monooxygenase [N-oxide-forming] 2	Oryctolagus cuniculus	106-113
8443210-1	1993	Two diabetes-inducible forms of cytochrome P-450, named P-450ST-1 and -ST-2, were purified from the liver microsomes of streptozotocin-diabetic male rats by sodium cholate solubilization, octylamino-Sepharose 4B chromatography and high-performance liquid chromatography with DEAE-5PW and hydroxyapatite columns.	Sodium Cholate	157-171	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	32-48
8443210-1	1993	Two diabetes-inducible forms of cytochrome P-450, named P-450ST-1 and -ST-2, were purified from the liver microsomes of streptozotocin-diabetic male rats by sodium cholate solubilization, octylamino-Sepharose 4B chromatography and high-performance liquid chromatography with DEAE-5PW and hydroxyapatite columns.	Sodium Cholate	157-171	interleukin 1 receptor-like 1	Rattus norvegicus	56-75
8509992-1	1993	A 3 beta-hydroxysteroid dehydrogenase/delta 4-delta 5-isomerase (3 beta-HSD/isomerase) has been purified to homogeneity from the pig adrenal microsomes by solubilization with sodium cholate, followed by some conventional column chromatographies.	Sodium Cholate	175-189	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase	Sus scrofa	65-75
1944241-1	1991	Angiotensin II (Ang-II) receptors were solubilized from differentiated N1E-115 neuroblastoma cell membranes with the zwitterionic detergent 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate (CHAPS), whereas other detergents, such as digitonin, sodium cholate, and Triton X-100, were much less effective.	Sodium Cholate	252-266	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	0-14
1627548-8	1992	However, P450 PB-1 was reduced in the presence of the phospholipid mixture and sodium cholate instead of DLPC.	Sodium Cholate	79-93	cytochrome P450, family 2, subfamily c, polypeptide 12	Rattus norvegicus	9-18
1313007-7	1992	Furthermore, the partially purified bovine brain PLC-gamma 1 fraction also was found to be associated with the gelsolin complex and the association was released by the addition of 1% sodium cholate.	Sodium Cholate	183-197	phospholipase C gamma 1	Bos taurus	49-60
1313007-7	1992	Furthermore, the partially purified bovine brain PLC-gamma 1 fraction also was found to be associated with the gelsolin complex and the association was released by the addition of 1% sodium cholate.	Sodium Cholate	183-197	gelsolin	Bos taurus	111-119
1639811-7	1992	The microsomal Mg(2+)-ATP-dependent CYP2E1 proteolysis could not be solubilized with high salt and 0.05% sodium cholate, indicating the action of membrane-integrated protease(s).	Sodium Cholate	105-119	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	36-42
1320935-1	1992	Phosphoinositide phospholipase C (PLC) activity extracted from bovine liver plasma membranes with sodium cholate was stimulated by GTP gamma S-activated G alpha q/G alpha 11, whereas the enzyme from liver cytosol was not.	Sodium Cholate	98-112	phospholipase C beta 1	Bos taurus	0-32
1320935-1	1992	Phosphoinositide phospholipase C (PLC) activity extracted from bovine liver plasma membranes with sodium cholate was stimulated by GTP gamma S-activated G alpha q/G alpha 11, whereas the enzyme from liver cytosol was not.	Sodium Cholate	98-112	G protein subunit alpha 11	Bos taurus	163-173
2168393-2	1990	The purification of the major PLC in KCl extract from normal Drosophila heads was achieved by sequential column chromatography on DEAE-Sepharose CL-6B, Mono Q, Superose 12, Mono S, second Mono S, and second Mono Q, followed by column chromatography on Superose 12 in the presence of 1% sodium cholate.	Sodium Cholate	286-300	no receptor potential A	Drosophila melanogaster	30-33
1721947-2	1991	The method is based on coupled enzymatic reactions in two steps: (1) esterified cholesterol hydrolysis by cholesterol esterase in the presence of sodium cholate and (2) cholesterol oxidation by cholesterol oxidase and chemiluminescent assay of the released hydrogen peroxide in peroxidase reaction with luminol and p-iodophenol.	Sodium Cholate	146-160	carboxyl ester lipase	Homo sapiens	106-126
1676625-1	1991	We purified two diabetes-inducible and insulin-sensitive forms of cytochrome P-450, named P-450AL-1 and AL-2, from the liver microsomes of alloxan-diabetic male rats, using sodium cholate solubilization, octylamino-Sepharose 4B chromatography, and HPLC with diethylaminoethyl-5PW and hydroxyapatite columns.	Sodium Cholate	173-187	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	66-82
1977093-1	1990	The bovine striatal dopamine D1 receptor was solubilized with a combination of sodium cholate and NaCl in the presence of phospholipids, following treatment of membranes with a dopaminergic agonist (SKF-82526-J) or antagonist (SCH-23390).	Sodium Cholate	79-93	dopamine receptor D1	Bos taurus	20-40
2166590-7	1990	Octyl glucoside and sodium cholate also uncoupled receptor regulation of phospholipase C but only at concentrations where solubilization of membrane proteins occurred.	Sodium Cholate	20-34	LOC100009319	Oryctolagus cuniculus	73-88
2153114-9	1990	Anionic detergents such as sodium deoxycholate or sodium cholate stimulate the activities of both enzymes, although DGK IV is stimulated more markedly than DGK I at lower concentrations.	Sodium Cholate	50-64	diacylglycerol kinase zeta	Rattus norvegicus	116-122
2380634-3	1990	A synthetic diet containing 50% sucrose, 15% cocoa butter, 1% cholesterol, and 0.5% sodium cholate was found to produce a depression in high density lipoprotein cholesterol (HDL-C) and an elevation of very low density lipoprotein (VLDL) and low density lipoprotein cholesterol (LDL-C) in the atherosclerosis-susceptible strain, C57BL/6J.	Sodium Cholate	84-98	CD320 antigen	Mus musculus	231-235
2153114-9	1990	Anionic detergents such as sodium deoxycholate or sodium cholate stimulate the activities of both enzymes, although DGK IV is stimulated more markedly than DGK I at lower concentrations.	Sodium Cholate	50-64	diacylglycerol kinase, iota	Rattus norvegicus	116-121
2294119-0	1990	Sodium cholate-induced changes in the conformation and activity of rat pancreatic cholesterol esterase.	Sodium Cholate	0-14	carboxyl ester lipase	Rattus norvegicus	71-102
1697997-1	1990	To produce a tri(n-butyl)phosphate/sodium-cholate-treated intermediate-purity factor VIII (FVIII) concentrate with a specific activity of about 1 IU/mg, we used a simple gel filtration step with Sephadex G25 to remove the solvent/detergent reagents from the final product.	Sodium Cholate	35-49	coagulation factor VIII	Homo sapiens	78-89
1697997-1	1990	To produce a tri(n-butyl)phosphate/sodium-cholate-treated intermediate-purity factor VIII (FVIII) concentrate with a specific activity of about 1 IU/mg, we used a simple gel filtration step with Sephadex G25 to remove the solvent/detergent reagents from the final product.	Sodium Cholate	35-49	coagulation factor VIII	Homo sapiens	91-96
2490103-4	1989	The response to sodium cholate (42 mV dec-1) was consistently lower than the ideal response (59 mV dec-1).	Sodium Cholate	16-30	deleted in esophageal cancer 1	Homo sapiens	38-43
34481856-3	2021	The hydrogels were evaluated as sorbents for sodium cholate (NaCA) and sodium deoxycholate (NaDCA) in water and 10 mM NaCl solutions.	Sodium Cholate	45-59	nascent polypeptide associated complex subunit alpha	Homo sapiens	61-65
2765544-4	1989	Using a radioimmunoassay, we have measured the concentration of endogenous transcortin in highly purified membrane preparations solubilized with sodium cholate.	Sodium Cholate	145-159	serpin family A member 6	Homo sapiens	75-86
2780547-2	1989	The expressed CEH activity was highly dependent on the presence of trihydroxy bile salts (cholate or one of its conjugates); maximum hydrolytic activity was observed in the presence of 10 mM sodium cholate.	Sodium Cholate	191-205	epoxide hydrolase 2	Rattus norvegicus	14-17
2780547-4	1989	In the presence of 10 mM sodium cholate, the CEH activity was maximal near pH 7 but was significant between pH 6 and 8.	Sodium Cholate	25-39	epoxide hydrolase 2	Rattus norvegicus	45-48
3355173-2	1988	Lysosomal glucocerebrosidase was extracted with sodium cholate and 1-butanol to render its beta-glucosidase activity dependent upon exogenous lipids.	Sodium Cholate	48-62	glucosylceramidase beta	Homo sapiens	0-28
2840071-3	1988	Rechromatography of peak GII on heparin-agarose, in the presence of 0.5% sodium cholate, resulted in separation of PLC and GTP-binding activities, and loss of GTP-dependent PLC activity.	Sodium Cholate	73-87	heparan sulfate proteoglycan 2	Homo sapiens	115-118
3395639-4	1988	The concentration of endogenous transcortin in sodium cholate-solubilized endometrium cell membranes was determined by the radioimmunoassay method.	Sodium Cholate	47-61	serpin family A member 6	Homo sapiens	32-43
3122839-0	1988	Characterization of complexes of egg yolk phosphatidylcholine and apolipoprotein A-II prepared in the absence and presence of sodium cholate.	Sodium Cholate	126-140	apolipoprotein A2	Homo sapiens	66-85
3190440-1	1988	Purified phenobarbital-induced rat liver cytochrome P-450 was incorporated in a reconstituted system containing NADPH-cytochrome P-450 reductase, dilauroyl phosphatidyl choline and sodium cholate.	Sodium Cholate	181-195	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	41-57
3040091-2	1987	(2) Laurylmaltoside, sodium cholate and Triton X-100 influenced the kinetics of cytochrome c oxidase cooperatively at detergent concentrations near their critical micelle concentration.	Sodium Cholate	21-35	cytochrome c oxidase subunit 6A1, mitochondrial	Bos taurus	80-100
3663692-1	1987	The kinetics of the bovine cholesterol esterase-catalyzed hydrolysis of three stereoisomers of alpha-tocopheryl acetate (alpha T-Ac) have been examined in vitro at 37 degrees C in the presence of dimyristoylphosphatidylcholine and sodium cholate.	Sodium Cholate	231-245	carboxyl ester lipase	Bos taurus	27-47
3735013-1	1986	The hydrolysis of 4-nitrophenylacetate and phenylsalicylate, catalyzed by human milk lipase in the presence of a range of concentrations of sodium cholate, has been measured at pH 7.3 and 37.5 degrees C, and maximum activity was observed for both substrates at 1 mmole/dm-3 bile salt.	Sodium Cholate	140-154	carboxyl ester lipase	Homo sapiens	80-91
3111543-4	1987	Lactosylsphingosine beta-galactosidase activities assayed in the absence and the presence of taurocholate (probably lactosylceramidase I) were deficient in fibroblasts from patients with globoid cell leukodystrophy, while the activity assayed with sodium cholate (probably lactosylceramidase II) was deficient in GM1 gangliosidosis fibroblasts.	Sodium Cholate	248-262	galactosidase beta 1	Homo sapiens	20-38
2963203-3	1987	For reconstitution the solubilized SR protein is incorporated into preformed French-pressed unilamellar vesicles that had been treated with 10-mM sodium cholate.	Sodium Cholate	146-160	RNA binding protein with serine rich domain 1	Homo sapiens	35-45
3718974-1	1986	Chick kidney mitochondrial 25-hydroxyvitamin D3 24-hydroxylase has been solubilized with sodium cholate and reconstituted with NADPH, beef adrenal ferredoxin, and beef adrenal ferredoxin reductase, each component being essential for maximal 24-hydroxylase activity.	Sodium Cholate	89-103	cytochrome P450 family 24 subfamily A member 1	Gallus gallus	27-62
4084561-4	1985	Incorporation of glycerol or sucrose and of sodium cholate into reaction mixtures equivalently affected the rates of both vitamin K and vitamin K 2,3-epoxide reduction, but in the case of epoxide metabolism, the ratios of vitamin KH2/vitamin K were much lower, suggesting that the second reaction has been partially uncoupled from the first.	Sodium Cholate	44-58	potassium voltage-gated channel modifier subfamily G member 1	Rattus norvegicus	230-233
3085988-1	1986	Sequential extraction of human spleen membranes with sodium cholate and n-butanol removes endogenous lipids and renders glucocerebrosidase activity dependent upon exogenous acidic lipids (e.g., phosphatidylserine, gangliosides) and a heat-stable activator protein (HSF).	Sodium Cholate	53-67	interleukin 6	Homo sapiens	265-268
4086481-4	1985	The in vitro transfer of heme from cytosol to microsome-bound cytochrome P-450 was stimulated by the addition of an NADPH-generating system to the incubation mixtures, and inhibited when the microsomes were solubilized with sodium cholate and Emulgen-913.	Sodium Cholate	224-238	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	62-78
3835282-5	1985	IMP were observed only when the incorporation of cytochrome P-450 was performed in the presence of detergent Emulgen 913 as specific additive to the initial protein-lipid-sodium cholate mixture or in the course of incubation of proteoliposomal suspensions at 37 degrees C. After the incorporation of cytochrome b5 into azolectin liposomes vesicular membranes contain IMP if the incorporated membrane protein: lipid ratio is at least 1:50.	Sodium Cholate	171-185	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	49-65
3935180-1	1985	Emulgen 913, Triton N-101 and sodium cholate were compared for their reconstituting action on the dimethylaniline N-demethylation system containing cytochrome P-450 and NADPH-cytochrome P-450 reductase.	Sodium Cholate	30-44	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	148-164
3935180-1	1985	Emulgen 913, Triton N-101 and sodium cholate were compared for their reconstituting action on the dimethylaniline N-demethylation system containing cytochrome P-450 and NADPH-cytochrome P-450 reductase.	Sodium Cholate	30-44	cytochrome p450 oxidoreductase	Homo sapiens	169-201
3929832-1	1985	Discoidal complexes of human apolipoprotein A-I-egg phosphatidylcholine-cholesterol were prepared by the sodium cholate dialysis procedure and were reacted to varying extents with the amino group reagents citraconic anhydride, diketene, and formaldehyde in the presence of sodium borohydride.	Sodium Cholate	105-119	apolipoprotein A1	Homo sapiens	29-47
2410544-1	1985	The determinant(s) of gonococcal resistance to killing by human phagocytes has been extracted from outer membrane vesicles (OMV) of a phagocyte-resistant strain, BS4 (agar), with sodium cholate (1%, w/v).	Sodium Cholate	179-193	negative regulator of ubiquitin like proteins 1	Homo sapiens	162-165
6150727-1	1984	The activity of inorganic pyrophosphatase (pyrophosphate phosphohydrolase, EC 3.6.1.1) extracted from rat-liver mitochondria with sodium cholate is distributed between three enzyme forms (I-III) which originally reside in the matrix (I) or the inner membrane (II and III).	Sodium Cholate	130-144	inorganic pyrophosphatase 1	Rattus norvegicus	16-41
6799213-3	1981	The binding reaction depended absolutely on the reductase, cytochrome P-450 and NADPH, and required dilauroyl phosphatidylcholine and sodium cholate for maximal activity.	Sodium Cholate	134-148	cytochrome P-450	Oryctolagus cuniculus	59-85
6549133-0	1984	Apolipoprotein B: removal of lipids by sodium cholate and reassociation of a lipid-free apoprotein with dipalmitoyl phosphatidylcholine.	Sodium Cholate	39-53	apolipoprotein B	Homo sapiens	0-16
6549133-1	1984	Apolipoprotein B (apoB) of human plasma low-density lipoprotein has been solubilized with sodium cholate added in an amount highly above its critical micellar concentration.	Sodium Cholate	90-104	apolipoprotein B	Homo sapiens	0-16
6549133-1	1984	Apolipoprotein B (apoB) of human plasma low-density lipoprotein has been solubilized with sodium cholate added in an amount highly above its critical micellar concentration.	Sodium Cholate	90-104	apolipoprotein B	Homo sapiens	18-22
6549133-3	1984	The circular dichroic spectra of the sodium cholate-solubilized apoB indicate significant heterogeneity within the fractions obtained by gel chromatography.	Sodium Cholate	37-51	apolipoprotein B	Homo sapiens	64-68
6734603-2	1984	The pseudo-first-order rate constants of hydrolysis of p-nitrophenylacetate, catalyzed by human milk lipase, have been measured in solutions of 0.01 mol dm-3 Bistris(2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-propane-1,3 -diol) buffer at 310.5 K, containing a range of concentrations of sodium taurocholate and sodium cholate, at pH 8.00 and of sodium cholate at pH 6.5.	Sodium Cholate	315-329	carboxyl ester lipase	Homo sapiens	96-107
6734603-2	1984	The pseudo-first-order rate constants of hydrolysis of p-nitrophenylacetate, catalyzed by human milk lipase, have been measured in solutions of 0.01 mol dm-3 Bistris(2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-propane-1,3 -diol) buffer at 310.5 K, containing a range of concentrations of sodium taurocholate and sodium cholate, at pH 8.00 and of sodium cholate at pH 6.5.	Sodium Cholate	349-363	carboxyl ester lipase	Homo sapiens	96-107
6428468-2	1984	It was found that during self-assembly of microsomal membranes solubilized with 4% sodium cholate and gel filtration through Sephadex LH-20 in the presence of isolated microsomal enzymes, two forms of cytochrome P-450, i.	Sodium Cholate	83-97	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	201-220
6422854-1	1984	Lysosomal glucocerebrosidase of human tissues is reversibly inactivated by extraction with sodium cholate and n-butanol.	Sodium Cholate	91-105	glucosylceramidase beta	Homo sapiens	0-28
6688622-6	1983	Ferrochelatase has an apparent molecular weight of approximately 40,000 by both sodium dodecyl sulfate-polyacrylamide gel electrophoresis and column chromatography on Sepharose CL-6B in the presence of 0.5% sodium cholate.	Sodium Cholate	207-221	FECH	Bos taurus	0-14
6407531-1	1983	Complexes of egg yolk phosphatidylcholine and apolipoprotein A-I were prepared by a detergent (sodium cholate)-dialysis method and characterized by gradient gel electrophoresis, gel filtration, electron microscopy and chemical analysis.	Sodium Cholate	95-109	apolipoprotein A1	Homo sapiens	46-64
6817809-3	1982	In vitro, the association of apolipoprotein A-I with physiological phosphatidylcholines can be catalyzed by mixing the protein and lipid with sodium cholate, which is removed by chromatography.	Sodium Cholate	142-156	apolipoprotein A1	Homo sapiens	29-47
6802835-1	1982	Micellar complexes of human apolipoprotein A-I and phosphatidylcholine, with or without cholesterol, were prepared by adding apolipoprotein A-I (apo A-I) to sodium cholate-lipid mixtures.	Sodium Cholate	157-171	apolipoprotein A1	Homo sapiens	28-46
6802116-7	1982	Inclusion of 0.1 M sodium cholate in the assay system, however, led to identical immunoreactivity of dimeric apo A-II and the reduced and carboxymethylated protein.	Sodium Cholate	19-33	apolipoprotein A2	Homo sapiens	109-117
6799515-8	1982	Sodium cholate, a known inhibitor of the acyl-CoA:lysophosphatide acyltransferase, completely inhibited this transfer reaction.	Sodium Cholate	0-14	HPS3, biogenesis of lysosomal organelles complex 2 subunit 1	Mus musculus	46-49
6457631-4	1981	Qualitatively, the results demonstrate that a significant portion of the observed decrease in the extent of recombination for rhodopsin solubilized in either sodium cholate or Tween 80 may be attributed to the partition of retinal into detergent micelles and that a detergent-induced protein denaturation need not be invoked to explain the data.	Sodium Cholate	158-172	rhodopsin	Homo sapiens	126-135
7295672-1	1981	Phospholipid-free rhodopsin has been purified in the detergents sodium cholate and octaethylene glycol n-dodecyl ether (C12E8).	Sodium Cholate	64-78	rhodopsin	Homo sapiens	18-27
7295672-5	1981	In sodium cholate, the smallest species present was found to be a trimer of the rhodopsin polypeptide chain, and this association was unaffected by exposure to light.	Sodium Cholate	3-17	rhodopsin	Homo sapiens	80-89
7280048-0	1981	The circular dichroism of sodium cholate solubilized rhodopsin.	Sodium Cholate	26-40	rhodopsin	Homo sapiens	53-62
18462-2	1977	CDP-diglyceride:inositol transferase, which catalyzes the final step of the de novo synthesis of phosphatidylinositol, was solubilized by sodium cholate from microsomes prepared from rat liver and purified by ammonium sulfate fractionation, sucrose density gradient centrifugation, and DEAE-cellulose column chromatography.	Sodium Cholate	138-152	cut-like homeobox 1	Rattus norvegicus	0-3
7443070-1	1980	The ionic detergent sodium cholate, in the presence of 1 M NaCl, solubilizes a 20S acetylcholinesterase from chick retina and other brain tissues previously extracted with a buffered solution containing 1% Triton X-100 and 1 M NaCl.	Sodium Cholate	20-34	acetylcholinesterase (Cartwright blood group)	Gallus gallus	83-103
6791141-0	1980	Effect of sodium cholate on the NADPH cytochrome P-450 reductase activity in the reconstituted rabbit pulmonary mixed-function oxidase system.	Sodium Cholate	10-24	NADPH--cytochrome P450 reductase	Oryctolagus cuniculus	32-64
7390973-1	1980	A phospholipase A2 bound tightly to the particulate fractions of rat ascites hepatoma cells was purified approximately 13,000-fold with a reasonably high yield (34%) by extraction with sodium cholate, ammonium sulfate fractionation, solubilization with sodium dodecyl sulfate, column chromatographies on Sephadex G-150 in the presence of sodium dodecyl sulfate, and on DEAE-cellulose and CM-cellulose in the presence of Triton X-100.	Sodium Cholate	185-199	phospholipase A2 group IB	Rattus norvegicus	2-18
905252-2	1977	Anionogenic sodium cholate, nonionogenic twin-80 and cationoactive ethonium depressed the action of the antidiuretic hormone.	Sodium Cholate	12-26	arginine vasopressin	Homo sapiens	104-124
33713773-1	2021	The present study reports the multi-technique results of the interaction of a series of bile salts, sodium cholate (NaC), sodium taurocholate (NaTC), sodium deoxycholate (NaDC), and sodium taurodeoxycholate (NaTDC) with Trypsin under the experimental conditions of 25  C and pH 7.0.	Sodium Cholate	100-114	synuclein alpha	Homo sapiens	116-119
1081883-2	1975	As a result of this extraction of rhodopsin with anion detergent (sodium cholate) in the concentrations not exceeding the critical concentration of micelloformation increases, and spontaneous release of rhodopsin into water phase is observed.	Sodium Cholate	66-80	rhodopsin	Homo sapiens	34-43
4454036-0	1974	Alteration of the kinetics of thrombin-catalyzed hydrolysis of amino acid ester substrates by sodium cholate and other steroids.	Sodium Cholate	94-108	coagulation factor II, thrombin	Homo sapiens	30-38
14800441-0	1951	The influence of sodium choleate on the hydrolysis of various esters by preparations of pancreatic lipase.	Sodium Cholate	17-32	pancreatic lipase	Homo sapiens	88-105
11812-1	1976	The kinetics of recombination of 11-cis-retinal with bleached rod outer segments and sodium cholate solubilized rhodopsin have been investigated.	Sodium Cholate	85-99	rhodopsin	Homo sapiens	112-121
931995-3	1976	Cytochrome P -450 was prepared either by sodium cholate treatment and ammonium sulfate fractionation or by subtilisin and sodium deoxycholate treatment followed by DEAE-cellulose chromatography.	Sodium Cholate	41-55	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	0-17
931995-11	1976	The use of increasing amounts of sodium cholate in the solubilization of cytochrome P -450 resulted in a gradual decrease of 25-hydroxylase activity and a gradual increase of 26-hydroxylase activity.	Sodium Cholate	33-47	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	73-90
4433516-0	1974	The characterization of sodium cholate solubilized rhodopsin.	Sodium Cholate	24-38	rhodopsin	Homo sapiens	51-60
32623121-4	2020	The formulation of DX with sodium cholate (NaC) will reduce aqueous solubility through charge neutralization and hydrophobic interactions thus facilitating DX encapsulation into poloxamer (F127) micelles, increasing drug latency.	Sodium Cholate	27-41	synuclein alpha	Homo sapiens	43-46
31033595-3	2019	In a previous study, rats fed 1% (wt/wt) sodium cholate had increased AQP3, 7, and 8 levels, suggesting AQP involvement in bile acid diarrhea (BAD).	Sodium Cholate	41-55	aquaporin 3 (Gill blood group)	Rattus norvegicus	70-74
32536398-6	2020	The encapsulation process of bile surfactant, sodium cholate (NaC) was investigated by isothermal titration calorimeter (ITC), and the thermodynamic parameters were determined.	Sodium Cholate	46-60	synuclein alpha	Homo sapiens	62-65
31715455-3	2020	The significant decrease in 1-NpOH fluorescence intensity in niosome-bile salt mixed system at both lower (10  C) and higher (50  C) temperatures indicates the bile salts [sodium cholate (NaC) and sodium deoxycholate (NaDC)] induce perturbation of niosome membranes.	Sodium Cholate	172-186	synuclein alpha	Homo sapiens	188-191
31130578-5	2019	In this study, sulfur-free sodium cholate (SC) was applied as the dispersant of carbide nanoparticles for the SPEED method and AF4 measurements.	Sodium Cholate	27-41	AF4/FMR2 family member 1	Homo sapiens	127-130
31130578-5	2019	In this study, sulfur-free sodium cholate (SC) was applied as the dispersant of carbide nanoparticles for the SPEED method and AF4 measurements.	Sodium Cholate	43-45	AF4/FMR2 family member 1	Homo sapiens	127-130
31836385-5	2020	The uricase/carboxymethylcellulose dispersed carbon nanotube/gold thin film biosensor shows the best sensing performance compared to that with sodium cholate surfactant in terms of higher current and lower detection potential.	Sodium Cholate	143-157	urate oxidase (pseudogene)	Homo sapiens	4-11
31902896-1	2020	The secondary structures of human serum albumin (HSA) and bovine serum albumin (BSA) were disrupted in the solution of sodium dodecyl sulfate (SDS), while being hardly damaged in the solution of the bile salt, sodium cholate (NaCho).	Sodium Cholate	210-224	albumin	Homo sapiens	34-47
31902896-1	2020	The secondary structures of human serum albumin (HSA) and bovine serum albumin (BSA) were disrupted in the solution of sodium dodecyl sulfate (SDS), while being hardly damaged in the solution of the bile salt, sodium cholate (NaCho).	Sodium Cholate	210-224	albumin	Homo sapiens	65-78
31108462-4	2019	HC feeding increased liver cholesterol content, which downregulated Srebp2 and Hmgcr expression, while sodium cholate administration decreased Cyp7a1 and Cyp8b1 mRNA levels, suggesting the downregulation of bile acid synthesis through the classical pathway.	Sodium Cholate	103-117	cytochrome P450, family 7, subfamily a, polypeptide 1	Mus musculus	143-149
31108462-4	2019	HC feeding increased liver cholesterol content, which downregulated Srebp2 and Hmgcr expression, while sodium cholate administration decreased Cyp7a1 and Cyp8b1 mRNA levels, suggesting the downregulation of bile acid synthesis through the classical pathway.	Sodium Cholate	103-117	cytochrome P450, family 8, subfamily b, polypeptide 1	Mus musculus	154-160
30279382-3	2018	The aim of the present work was to study the action of sodium cholate (NaC) and N-dodecyl-beta-D-maltoside (DDM), using a small intestinal mucosal explant system.	Sodium Cholate	55-69	synuclein alpha	Homo sapiens	71-74
30187493-0	2019	Mango phenolics increase the serum apolipoprotein A1/B ratio in rats fed high cholesterol and sodium cholate diets.	Sodium Cholate	94-108	apolipoprotein A1	Rattus norvegicus	35-52
29554645-2	2018	sodium cholate (NaC) and sodium deoxycholate (NaDC) with three ethylene polyoxide-polypropylene polyoxide (PEO-PPO-PEO) triblock copolymers with similar PPO but varying PEO micelles with a focus on the effect of pH on mixed micelles.	Sodium Cholate	0-14	synuclein alpha	Homo sapiens	16-19
28004910-3	2017	The nanoparticles were further functionalized with apoA-I and DXS via sodium cholate mediation and electrostatic interaction, respectively.	Sodium Cholate	70-84	apolipoprotein A1	Homo sapiens	51-57
29263668-4	2017	To overcome these challenges, we developed a micellar formulation that consists of sodium cholate (NaC) and monomethoxy poly (ethylene glycol)-block-poly (d,l-lactide) (mPEG-PDLLA).	Sodium Cholate	83-97	synuclein alpha	Homo sapiens	99-102
25853480-1	2016	In present study, two types of micelles based on sodium cholate (NaC) were prepared through non-covalent bonding interaction and the potential of micelles as oral drug delivery systems for paclitaxel (PTX) was evaluated.	Sodium Cholate	49-63	synuclein alpha	Homo sapiens	65-68
27707051-5	2016	Approximately, 85-90% BA could be loaded onto HSA in the presence of Tween 20 (T20) and sodium cholate (NaC).	Sodium Cholate	88-102	synuclein alpha	Homo sapiens	104-107
27698255-3	2016	In the present study, poly (lactide-co-e-caprolactone) (PLCL) core-shell nanofiber-coated film of stent, loaded with ethylene diamine tetraacetic acid and sodium cholate in core layer, was fabricated by co-axial electrospinning for treating gallstone disease.	Sodium Cholate	155-169	phospholipase C like 1 (inactive)	Homo sapiens	56-60
26872299-2	2016	This treatment is applied to the exchange reaction of sodium cholate (SC) molecules on SWNTs and the ds-DNAs d(A)20 -d(T)20 and nuclear factor (NF)-kappaB decoy.	Sodium Cholate	54-68	nuclear factor kappa B subunit 1	Homo sapiens	128-154
27037785-5	2016	In-vivo toxicity and bioimaging studies of sodium cholate (NaC) templated AuNCs were carried out at different developmental stages of zebrafish embryos.	Sodium Cholate	43-57	melanocyte inducing transcription factor a	Danio rerio	59-62
26964921-10	2016	The values of binding constant for sodium cholate (NaC) and sodium taurocholate (NaTC) are 2.66 x 10(5) and 2.72 x 10(4) M(-1) respectively.	Sodium Cholate	35-49	synuclein alpha	Homo sapiens	51-54
26964921-11	2016	Sodium cholate (NaC) was found to show strong interaction towards quercitin (QT) due to more electron density on oxygen atom of carboxylate ion.	Sodium Cholate	0-14	synuclein alpha	Homo sapiens	16-19
26901282-2	2016	Detailed ITC characterization of bile micelle formation as well as the chiral recognition capabilities of sodium cholate (NaC), deoxycholate (NaDC), and taurodeoxycholate (NaTDC) micelle systems are reported.	Sodium Cholate	106-120	synuclein alpha	Homo sapiens	122-125
25318019-4	2014	The focus of the present work is to investigate the interaction of NB with two bile salts sodium deoxycholate (NaDC) and sodium cholate (NaC) by spectroscopic techniques.	Sodium Cholate	121-135	synuclein alpha	Homo sapiens	137-140
25552345-1	2015	We report a novel green chemical approach for the synthesis of blue light-emitting and water-soluble Ag subnanoclusters, using sodium cholate (NaC) as a template at a concentration higher than the critical micelle concentration (CMC) at room temperature.	Sodium Cholate	127-141	melanocyte inducing transcription factor a	Danio rerio	143-146
25549008-1	2015	The present study demonstrates a detailed characterization of the interaction of a series of bile salts, sodium deoxycholate (NaDC), sodium cholate (NaC), and sodium taurocholate (NaTC), with a model transport protein, human serum albumin (HSA).	Sodium Cholate	133-147	synuclein alpha	Homo sapiens	149-152
25549008-1	2015	The present study demonstrates a detailed characterization of the interaction of a series of bile salts, sodium deoxycholate (NaDC), sodium cholate (NaC), and sodium taurocholate (NaTC), with a model transport protein, human serum albumin (HSA).	Sodium Cholate	133-147	albumin	Homo sapiens	225-238
25517159-7	2014	Conversely, dimerization of CcO induced by sodium cholate significantly increases its kinetic stability of only the first step (the half-life increases at 37 C).	Sodium Cholate	43-57	cytochrome c oxidase subunit 6A1, mitochondrial	Bos taurus	28-31
25958529-0	2014	Protective effects of poly(lactic-co-glycolic acid) nanoparticles loaded with erythropoietin stabilized by sodium cholate against glutamate-induced neurotoxicity.	Sodium Cholate	107-121	erythropoietin	Homo sapiens	78-92
25958529-1	2014	The final aim of this study was to confirm the neuroprotective effects of recombinant human erythropoietin (rhEPO)-loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles stabilized by sodium cholate (rhEPO-Ch-NP) and compare their effects with those of rhEPO using an in vitro model of cerebral ischemia.	Sodium Cholate	187-201	erythropoietin	Homo sapiens	92-106
21826348-1	2011	Sodium cholate (NaC) and sodium deoxycholate (NaDC) in binary and ternary aqueous mixtures were investigated by means of surface tension, electron paramagnetic resonance spectroscopy (EPR), small angle neutron scattering (SANS) and mutual diffusion coefficient analysis.	Sodium Cholate	0-14	X-linked Kx blood group	Homo sapiens	16-19
26556194-6	2014	Different types of enzyme inhibitors, like sodium cholate, camostat, mesilate, bacitracin, leupeptin, and so forth, have been used to prevent insulin from enzymatic degradation.	Sodium Cholate	43-57	insulin	Homo sapiens	142-149
23930911-8	2013	In presence of sodium deoxycholate (NaDC) and sodium cholate (NaC) in DPPC vesicles, ANS experiences restriction in rotational mobility which is evident from the variation in steady-state fluorescence anisotropy and fluorescence anisotropy decay parameters.	Sodium Cholate	46-60	synuclein alpha	Homo sapiens	62-65
25127627-2	2014	The sample was extracted using the phase separation behavior exhibited by the bile salt surfactant, sodium cholate (NaC), upon addition of sodium dodecylsulfate (SDS) in the presence of acid at room temperature.	Sodium Cholate	100-114	synuclein alpha	Homo sapiens	116-119
17978759-2	2007	The interactions of two bile salt molecules, sodium cholate (NaC) and sodium deoxycholate (NaDC) with biological phospholipid model membranes are considered.	Sodium Cholate	45-59	synuclein alpha	Homo sapiens	61-64
19788314-1	2009	In this study, we describe the use of a sodium cholate suspension-dialysis method to adsorb the redox enzyme glucose oxidase (GOX) onto single-walled carbon nanotubes (SWNT).	Sodium Cholate	40-54	hydroxyacid oxidase 1	Homo sapiens	109-124
19788314-1	2009	In this study, we describe the use of a sodium cholate suspension-dialysis method to adsorb the redox enzyme glucose oxidase (GOX) onto single-walled carbon nanotubes (SWNT).	Sodium Cholate	40-54	hydroxyacid oxidase 1	Homo sapiens	126-129
19697316-0	2009	CE-LIF chiral separation of aspartic acid and glutamic acid enantiomers using human serum albumin and sodium cholate as dual selectors.	Sodium Cholate	102-116	LIF interleukin 6 family cytokine	Homo sapiens	3-6
20976368-5	2011	The interaction of fisetin with sodium cholate (NaC) and some other bile salts has been studied in detail, using the intrinsic fluorescence of different prototropic forms of fisetin: neutral form (FN, lambda(ex) 369 nm, lambda(em) ~ 400 nm), ground state anion form ((FA)(GS), lambda(ex) 418 nm, lambda(em) 490 nm) and phototautomer (FT, lambda(ex) 369 nm, lambda(em) 540 nm).	Sodium Cholate	32-46	synuclein alpha	Homo sapiens	48-51
19153035-2	2009	The inclusion of a biological surfactant like sodium cholate (NaC) into PNIPAM could lead a better biocompatibility when the materials are used for biomedical applications.	Sodium Cholate	46-60	synuclein alpha	Homo sapiens	62-65
16457837-0	2006	Sodium dodecyl sulfate promoting a cooperative association process of sodium cholate with bovine serum albumin.	Sodium Cholate	70-84	albumin	Homo sapiens	97-110
16959453-7	2006	The application of a nasal spray (NS) solution containing 0.5% sodium cholate resulted in a significant improvement (P<0.05) in both the rate and extent of absorption of MCP HCl where the T(max) achieved was 23.3min as compared to 50min in case of the oral solution while the area under the serum concentration-time curve (AUC(0-infinity)) were 506.1, 434.9 and 278.7microg/mlmin for IV, NS and oral solutions, respectively.	Sodium Cholate	63-77	CD46 molecule	Rattus norvegicus	173-176
16555923-2	2006	The objective of this work was to explore how the nonplanarity and size of guests (biphenyl [BP], 1-1"-binaphthyl [BNP] and dibenz[b,f]oxepin [DBX]) affected their binding affinity and dynamics to sodium cholate (NaC) aggregates.	Sodium Cholate	197-211	X-linked Kx blood group	Homo sapiens	213-216
16457837-1	2006	Sodium cholate (NaC) was used as a representative bile salt in the process of cooperative binding to bovine serum albumin (BSA) in a mixture with sodium dodecyl sulfate (SDS).	Sodium Cholate	0-14	synuclein alpha	Homo sapiens	16-19
16457837-1	2006	Sodium cholate (NaC) was used as a representative bile salt in the process of cooperative binding to bovine serum albumin (BSA) in a mixture with sodium dodecyl sulfate (SDS).	Sodium Cholate	0-14	albumin	Homo sapiens	108-121
16329463-11	2005	It was discovered that the purified Nt PLA2 essentially requires Ca2+, for the enzyme activity when the activity was determined using mixed-micellar phospholipid substrates with sodium cholate.	Sodium Cholate	178-192	phospholipase A2-alpha-like	Nicotiana tabacum	39-43
16597434-7	2006	The purified protein is a monomer in the presence of 1% sodium cholate as determined by gel filtration analysis, suggesting that this membrane anchor-truncated form of P450c21 is more soluble than the native form.	Sodium Cholate	56-70	steroid 21-hydroxylase	Bos taurus	168-175
11699836-3	2001	Of the bile salts/acids studied, incorporation of 100 mg of deoxycholic acid (DCA), sodium cholate (NaC), or sodium deoxycholate (NaDC) with insulin (10 U/Kg) showed that suppositories containing NaDC produced the highest area under the curve (AUC) and relative hypoglycemia (RH) of 290 +/- 83 mg%h and 28% +/- 8.1%, respectively.	Sodium Cholate	84-98	insulin	Canis lupus familiaris	141-148
15018951-3	2004	The sensitivity of the biosensor based on immobilization procedures of flavocytochrome P450scc by glutaric aldehyde is 13.8 nA microM(-1) and the detection limit is 300 microM with a coefficient of linearity 0.98 for cholesterol in the presence of sodium cholate as detergent.	Sodium Cholate	248-262	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	87-94
15040468-9	2003	These results show that these insulin suppositories containing 100 mg of sodium cholate and 200 U of insulin can serve as effective buffer against meal related hyperglycemia.	Sodium Cholate	73-87	insulin	Homo sapiens	30-37
15040468-4	2003	The results also show that insulin suppositories containing 100 mg sodium cholate and 200 U insulin resulted in a non significant differences in Cmax and AUC from those produced by S.C. injection of insulin (20 U) but significantly (p < 0.001) shorter Tmax.	Sodium Cholate	67-81	insulin	Homo sapiens	27-34
11914083-1	2002	Bovine heart cytochrome c oxidase (CcO), solubilized by either nonionic detergents or phospholipids, completely dimerizes upon the addition of bile salts, e.g., sodium cholate, sodium deoxycholate, or CHAPS.	Sodium Cholate	161-175	cytochrome c oxidase subunit 6A1, mitochondrial	Bos taurus	13-33
11914083-1	2002	Bovine heart cytochrome c oxidase (CcO), solubilized by either nonionic detergents or phospholipids, completely dimerizes upon the addition of bile salts, e.g., sodium cholate, sodium deoxycholate, or CHAPS.	Sodium Cholate	161-175	cytochrome c oxidase subunit 6A1, mitochondrial	Bos taurus	35-38
11914083-6	2002	Similarly, enzyme dispersed in 20 mM phospholipid requires 50 mM sodium cholate, concentrations that are commonly used to reconstitute CcO into small unilamellar vesicles.	Sodium Cholate	65-79	cytochrome c oxidase subunit 6A1, mitochondrial	Bos taurus	135-138
11914083-10	2002	The dimerization process is dependent upon a full complement of subunits; e.g., if subunits VIa and VIb are removed, the resulting monomeric CcO will not reassociate upon the addition of sodium cholate.	Sodium Cholate	187-201	cytochrome c oxidase subunit 6A1, mitochondrial	Bos taurus	141-144
11240372-0	2001	The optical interconversion of the P-450 and P-420 forms of neuronal nitric oxide synthase: effects of sodium cholate, mercury chloride and urea.	Sodium Cholate	103-117	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	35-90
9699412-1	1998	The results of interaction of the bile salts sodium dehydrocholate (NaDHC) and sodium cholate (NaC) with the water soluble polymer polyvinyl pyrrolidone (PVP) studied by the methods of conductance, surface tension, viscosity and calorimetry are reported.	Sodium Cholate	79-93	synuclein alpha	Homo sapiens	95-98
10409402-6	1999	A reconstituted system containing purified P450 1B1, rabbit liver NADPH-P450 reductase, and human liver epoxide hydrolase was found to catalyze benzo[a]pyrene to trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene at a rate of 0.86 nmol min(-)(1) nmol of P450(-)(1); the activities were found to be largely dependent on the presence of sodium cholate in the system.	Sodium Cholate	330-344	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	43-51
9767136-1	1998	The micellization of sodium cholate (NaC) was studied at 298.2 K by aqueous solubility at different pH values.	Sodium Cholate	21-35	synuclein alpha	Homo sapiens	37-40
9553144-7	1998	However, other detergents such as polydocanol, W-1, octyl glucoside, dodecyl maltoside, Tween 20, and sodium cholate allow varying degrees of Bax hetero- and homodimerization.	Sodium Cholate	102-116	BCL2-associated X protein	Mus musculus	142-145
11240372-2	2001	Sodium cholate and mercury chloride induced the conversion of nNOS from the P-450 to the P-420 form in concentration- and incubation time-dependent manners, and the nNOS activity decreased.	Sodium Cholate	0-14	nitric oxide synthase 1	Homo sapiens	62-66
11240372-2	2001	Sodium cholate and mercury chloride induced the conversion of nNOS from the P-450 to the P-420 form in concentration- and incubation time-dependent manners, and the nNOS activity decreased.	Sodium Cholate	0-14	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	76-81
11240372-2	2001	Sodium cholate and mercury chloride induced the conversion of nNOS from the P-450 to the P-420 form in concentration- and incubation time-dependent manners, and the nNOS activity decreased.	Sodium Cholate	0-14	nitric oxide synthase 1	Homo sapiens	165-169
11240372-3	2001	In the presence of glycerol, L-arginine and/or tetrahydrobiopterin, the sodium cholate-treated P-420 form could be reconverted to the P-450 form under constant experimental conditions, and the nNOS activity could also be restored.	Sodium Cholate	72-86	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	134-139
11240372-3	2001	In the presence of glycerol, L-arginine and/or tetrahydrobiopterin, the sodium cholate-treated P-420 form could be reconverted to the P-450 form under constant experimental conditions, and the nNOS activity could also be restored.	Sodium Cholate	72-86	nitric oxide synthase 1	Homo sapiens	193-197
11240372-7	2001	The nNOS monomer was more susceptible to sodium cholate.	Sodium Cholate	41-55	nitric oxide synthase 1	Homo sapiens	4-8
11240372-9	2001	These results suggested that nNOS was more stable as to exposure to sodium cholate, mercury chloride or urea in comparison to microsomal cytochrome P-450, which may be due to the different heme environment and protein structure.	Sodium Cholate	68-82	nitric oxide synthase 1	Homo sapiens	29-33
10320323-4	1999	Addition of pure human LCAT to LDL or palmitoyl-linoleoyl phosphatidylcholine/sodium cholate (PLPC) micelles inhibits the oxidation-dependent accumulation of both conjugated dienes and lipid hydroperoxides.	Sodium Cholate	78-92	lecithin-cholesterol acyltransferase	Homo sapiens	23-27
9565681-5	1998	We further demonstrate that feeding mice with diets containing cholestyramine or sodium cholate increases mRNA-expression of ES-x in liver 2.5- to 3-fold.	Sodium Cholate	81-95	carboxylesterase 1G	Mus musculus	125-129
9442017-5	1998	Importantly, PtdIns(3,4,5)P3, but not PtdIns(4,5)P2, markedly enhances the ARF exchange activity of GRP1 in a reaction mixture containing dimyristoylphosphatidylcholine micelles, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonic acid, and a low concentration of sodium cholate.	Sodium Cholate	269-283	Rud3p	Saccharomyces cerevisiae S288C	100-104
9372642-2	1997	Sodium cholate (20 and 50 mg/capsule) produced a dose-related enhancement of an insulin-induced decrease in the blood glucose level.	Sodium Cholate	0-14	insulin	Oryctolagus cuniculus	80-87
9372642-3	1997	Insulin capsules containing sodium cholate (50 mg/capsule) produced a steady reduction of the blood glucose level reaching 69% of the initial values (P < 0.01) by 3 h and 48% (P < 0.001) by 5 h after administration.	Sodium Cholate	28-42	insulin	Oryctolagus cuniculus	0-7