PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
35526097-3	2022	Mechanistically, Bifonazole binds ACE2 around residue K353, which consequently prevents association with RBD, thereby impacting entry and replication of Spike-pseudotyped viruses as well as native SARS-CoV-2 and its variants of concern (VOC).	Fluoroglycofen	54-58	angiotensin converting enzyme 2	Homo sapiens	34-38
35526097-3	2022	Mechanistically, Bifonazole binds ACE2 around residue K353, which consequently prevents association with RBD, thereby impacting entry and replication of Spike-pseudotyped viruses as well as native SARS-CoV-2 and its variants of concern (VOC).	Fluoroglycofen	54-58	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	153-158
35295301-13	2022	The docking results suggest that the key residues K353 and G496 may affect the binding energies and dynamics between the inferred anti-SARS-CoV-2 chemical agents and the junction of the spike protein-ACE2 interface.	Fluoroglycofen	50-54	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	186-191
35295301-13	2022	The docking results suggest that the key residues K353 and G496 may affect the binding energies and dynamics between the inferred anti-SARS-CoV-2 chemical agents and the junction of the spike protein-ACE2 interface.	Fluoroglycofen	50-54	angiotensin converting enzyme 2	Homo sapiens	200-204
33501438-6	2021	Our recent analysis of the highly transmissible N501Y lineage B.1.1.7 mutation in SARS-CoV-2 also supports this model, identifying a less promiscuous Y501 interaction with ACE2 that favors more stable functional binding with the K353 site alone.	Fluoroglycofen	229-233	angiotensin converting enzyme 2	Homo sapiens	172-176
27690098-6	2016	The site-directed mutagenesis combined with computational modelling identified that K347 and K353, located in the turret motif of the Kv4.2, and E4/E5, D20/D21 in BmP02 are key residues to interact with BmP02 through electrostatic force.	Fluoroglycofen	93-97	potassium voltage-gated channel subfamily D member 2	Homo sapiens	134-139