PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 25564193-8 2015 Moreover, a diagnosis x genotype interaction was found for the GMV of the left precuneus, and the effect of the COMT gene on GMV was due mainly to cortical thickness rather than cortical surface area. Guanosine-5'-Phosphovanadate 125-128 catechol-O-methyltransferase Homo sapiens 112-116 25809805-12 2015 Voxel-based analysis showed that NP4 scores [VitB12 and D] were positively associated with METglc and GMV, and negatively associated with PiB retention in AD-vulnerable regions (p<0.001). Guanosine-5'-Phosphovanadate 102-105 proteinase 3 Homo sapiens 33-36 25809805-13 2015 In addition, both METglc and GMV were positively associated with NP2 scores [VitE and PUFA], and negatively associated with NP5 scores [Fats] (p<0.001), and METglc was positively associated with higher NP3 scores [Anti-oxidants and Fibers] (p<0.001). Guanosine-5'-Phosphovanadate 29-32 neuropilin 2 Homo sapiens 65-68 25809805-13 2015 In addition, both METglc and GMV were positively associated with NP2 scores [VitE and PUFA], and negatively associated with NP5 scores [Fats] (p<0.001), and METglc was positively associated with higher NP3 scores [Anti-oxidants and Fibers] (p<0.001). Guanosine-5'-Phosphovanadate 29-32 pumilio RNA binding family member 3 Homo sapiens 86-90 25809805-13 2015 In addition, both METglc and GMV were positively associated with NP2 scores [VitE and PUFA], and negatively associated with NP5 scores [Fats] (p<0.001), and METglc was positively associated with higher NP3 scores [Anti-oxidants and Fibers] (p<0.001). Guanosine-5'-Phosphovanadate 29-32 leukemia NUP98 fusion partner 1 Homo sapiens 202-205 25659473-2 2015 This study aimed to determine the relation between pre-therapy OFC GMV or asymmetry, emotional decision-making and CBTp responsiveness. Guanosine-5'-Phosphovanadate 67-70 opsin 1, short wave sensitive Homo sapiens 115-119 25659473-9 2015 In the CBTp+SC group, greater OFC GMV correlated with positive symptom improvement, specifically hallucinations and persecution. Guanosine-5'-Phosphovanadate 34-37 opsin 1, short wave sensitive Homo sapiens 7-11 26370382-6 2015 In fully adjusted models, GMV was inversely associated with coronary artery CP (parameter estimate [beta] -0.47 [SE 0.15], P = 0.002; carotid artery CP (beta -1.92 [SE 0.62], P = 0.002; and aorta CP [beta -0.10 [SE 0.03] P = 0.002), whereas HbA1c and CRP did not associate with cerebral volumes. Guanosine-5'-Phosphovanadate 26-29 C-reactive protein Homo sapiens 251-254 25564193-10 2015 These findings suggest that the COMTMet variant is associated with the disruption of dopaminergic influence on gray matter in schizophrenia, and the effect of the COMT gene on GMV in schizophrenia is mainly due to changes in cortical thickness rather than in cortical surface area. Guanosine-5'-Phosphovanadate 176-179 catechol-O-methyltransferase Homo sapiens 32-36 23047233-3 2012 GmV was decomposed as a function of the temperature and studied with TGA, DRX, FT-Infrared, Temperature-Programmed Surface Reaction (TPSR) and DFT. Guanosine-5'-Phosphovanadate 0-3 T-box transcription factor 1 Homo sapiens 69-72 24196483-4 2014 The GMV fraction was composed of podocin/podocalyxin-positive irregularly shaped membranous vesicles and podocin/podocalyxin-negative classical exosomes. Guanosine-5'-Phosphovanadate 4-7 NPHS2 stomatin family member, podocin Homo sapiens 33-40 24196483-4 2014 The GMV fraction was composed of podocin/podocalyxin-positive irregularly shaped membranous vesicles and podocin/podocalyxin-negative classical exosomes. Guanosine-5'-Phosphovanadate 4-7 podocalyxin like Homo sapiens 41-52 24196483-4 2014 The GMV fraction was composed of podocin/podocalyxin-positive irregularly shaped membranous vesicles and podocin/podocalyxin-negative classical exosomes. Guanosine-5'-Phosphovanadate 4-7 NPHS2 stomatin family member, podocin Homo sapiens 105-112 24196483-4 2014 The GMV fraction was composed of podocin/podocalyxin-positive irregularly shaped membranous vesicles and podocin/podocalyxin-negative classical exosomes. Guanosine-5'-Phosphovanadate 4-7 podocalyxin like Homo sapiens 113-124 23962795-4 2013 Coordinates were extracted from clusters of significant GMV difference between patients with JME and HC subjects. Guanosine-5'-Phosphovanadate 56-59 myoclonic epilepsy, juvenile, 2 Homo sapiens 93-96 23266749-7 2013 These findings suggest that the polymorphism in the KIBRA gene affects GMV and the function of the DMN and ECN. Guanosine-5'-Phosphovanadate 71-74 WW and C2 domain containing 1 Homo sapiens 52-57 20594947-6 2010 The whole brain GMV/WMV did not differ between MDD patients and HCs; however, the regional GMV of the right pre-supplementary motor area (pre-SMA) was smaller in MDD patients. Guanosine-5'-Phosphovanadate 91-94 survival of motor neuron 1, telomeric Homo sapiens 142-145 22206963-4 2012 Voxel-based morphometry was used to investigate the relationship between fasting and postprandial plasma PYY concentrations and regional gray matter volume (GMV). Guanosine-5'-Phosphovanadate 157-160 peptide YY Homo sapiens 105-108 20483373-3 2010 Moreover, an increase in GMV was found in the parieto-temporo-occipital association cortex in asymptomatic Parkin and ATP13A2 MC. Guanosine-5'-Phosphovanadate 25-28 ATPase cation transporting 13A2 Homo sapiens 118-125 20483373-5 2010 Asymptomatic PINK1 and LRRK2 MC also revealed smaller GMV in the hippocampal region, which might play a role in the observed psychiatric disorders. Guanosine-5'-Phosphovanadate 54-57 PTEN induced kinase 1 Homo sapiens 13-18 20483373-5 2010 Asymptomatic PINK1 and LRRK2 MC also revealed smaller GMV in the hippocampal region, which might play a role in the observed psychiatric disorders. Guanosine-5'-Phosphovanadate 54-57 leucine rich repeat kinase 2 Homo sapiens 23-28 22595621-6 2012 In contrast, in the analysis of both the PDD subgroup and the entire PD (PDND + PDD) sample, we found significant negative CSF-GMV correlations for tau and phospho-tau and significant positive CSF-GMV correlations for Abeta in mostly frontal and temporal structures. Guanosine-5'-Phosphovanadate 127-130 microtubule associated protein tau Homo sapiens 148-151 22595621-6 2012 In contrast, in the analysis of both the PDD subgroup and the entire PD (PDND + PDD) sample, we found significant negative CSF-GMV correlations for tau and phospho-tau and significant positive CSF-GMV correlations for Abeta in mostly frontal and temporal structures. Guanosine-5'-Phosphovanadate 127-130 microtubule associated protein tau Homo sapiens 164-167 22206834-4 2012 We found that RT was positively correlated with the grey matter volume (GMV) bilaterally in cerebellar lobules IV/V, VI and VIII, in vermis VII/VIII and in left Crus I; CR was positively correlated with the GMV in the left lobule VI and Crus I. Guanosine-5'-Phosphovanadate 72-75 cytochrome c oxidase subunit 8A Homo sapiens 124-128 20594947-8 2010 These results indicate the GMV reduction of the pre-SMA at an early stage of depression, whereas the GMV of the hippocampus is associated with depressive characteristics. Guanosine-5'-Phosphovanadate 27-30 survival of motor neuron 1, telomeric Homo sapiens 52-55 16733674-8 2007 To conclude, macrocephaly in NF1 patients is related to increased GMV and WMV and corpus callosum enlargement. Guanosine-5'-Phosphovanadate 66-69 neurofibromin 1 Homo sapiens 29-32 19013250-9 2009 Brain regions showing a significant APOE epsilon4 allele load effect on GMV in AD included only some of those typically described as having greatest amyloid plaque deposition and atrophy. Guanosine-5'-Phosphovanadate 72-75 apolipoprotein E Homo sapiens 36-40 21324265-9 2010 Decline of GMV (P = 0.017), and BPV (P = 0.029) were significantly faster in APOE epsilon4-positive than in APOE epsilon4-negative patients in the 15-year model. Guanosine-5'-Phosphovanadate 11-14 apolipoprotein E Homo sapiens 77-81 21324265-9 2010 Decline of GMV (P = 0.017), and BPV (P = 0.029) were significantly faster in APOE epsilon4-positive than in APOE epsilon4-negative patients in the 15-year model. Guanosine-5'-Phosphovanadate 11-14 apolipoprotein E Homo sapiens 108-112 21324265-10 2010 In the 4- year model, a trend for faster decrease of GMV was found in APOE epsilon4-positive patients (P = 0.067). Guanosine-5'-Phosphovanadate 53-56 apolipoprotein E Homo sapiens 70-74 35145374-8 2021 These results indicate that SorCS2 methylation might mediate a reduced GMV in the precentral and posterior orbital gyri and therefore influence the pathology of children with ADHD. Guanosine-5'-Phosphovanadate 71-74 sortilin related VPS10 domain containing receptor 2 Homo sapiens 28-34 34561420-7 2021 Increased SLC25A24 methylation was also related to lower GMV in multiple brain regions in the overall cohort. Guanosine-5'-Phosphovanadate 57-60 solute carrier family 25 member 24 Homo sapiens 10-18 34732337-7 2022 In addition, the GMV in the right thalamus in the patients with UDP was positively associated with mRNA levels of CRY2, while the GMV in the right hippocampus in the patients with BDP was negatively associated with mRNA levels of PER3. Guanosine-5'-Phosphovanadate 17-20 cryptochrome circadian regulator 2 Homo sapiens 114-118 34732337-7 2022 In addition, the GMV in the right thalamus in the patients with UDP was positively associated with mRNA levels of CRY2, while the GMV in the right hippocampus in the patients with BDP was negatively associated with mRNA levels of PER3. Guanosine-5'-Phosphovanadate 130-133 period circadian regulator 3 Homo sapiens 230-234 34119573-8 2021 Both GMV and GMD were significant different among the three groups for the bilateral superior temporal gyrus, bilateral middle temporal gyrus, left lingual gyrus, bilateral caudate nucleus, right Fusiform gyrus and bilateral Thalamus (GRF correction, cluster-P < 0.01, voxel-P < 0.001). Guanosine-5'-Phosphovanadate 5-8 growth hormone releasing hormone Homo sapiens 235-238 34993881-9 2022 Increased serum urea concentrations, parathyroid hormone levels, and hemodialysis duration were independent risk factors for decreased GMV in patients undergoing hemodialysis (all P<0.05, FDR corrected). Guanosine-5'-Phosphovanadate 135-138 parathyroid hormone Homo sapiens 37-56 35221884-5 2021 We also analyzed age-related effects on GMV and ALFF values in the two patient groups (med-SZ and unmed-SZ). Guanosine-5'-Phosphovanadate 40-43 renin binding protein Homo sapiens 17-20 35221884-9 2021 Age-related GMV effects were seen in all regions, which showed group-level differences except fusiform gyrus. Guanosine-5'-Phosphovanadate 12-15 renin binding protein Homo sapiens 0-3 35136970-4 2022 The identified genetic factors may further affect people"s lifestyle habits and body/blood fat levels through the mediation of cereal/coffee intake, and the brain-wide expression pattern of gene CPLX3, a dedicated marker of subplate neurons that regulate cortical development and plasticity, may underlie the shared GMV-association patterns among the coffee/cereal intake and cognitive functions. Guanosine-5'-Phosphovanadate 316-319 complexin 3 Homo sapiens 195-200 33919311-4 2021 The results of voxel-based multiple regression analysis showed that blood levels of CypA, HO-1, and IRE1 were correlated with GMV on brain magnetic resonance imaging (MRI) in the entire population (p = 0.0005). Guanosine-5'-Phosphovanadate 126-129 peptidylprolyl isomerase A Homo sapiens 84-88 35275541-8 2022 RESULTS: Compared to KY + KK, MET showed reductions in GMV in left prefrontal, pre- and post-central, supramarginal, superior temporal and pericalcarine cortices, right paracentral, postcentral, superior and inferior parietal cortices, the banks of the superior temporal sulcus, and the pars opercularis. Guanosine-5'-Phosphovanadate 55-58 SAFB like transcription modulator Homo sapiens 30-33 33919311-4 2021 The results of voxel-based multiple regression analysis showed that blood levels of CypA, HO-1, and IRE1 were correlated with GMV on brain magnetic resonance imaging (MRI) in the entire population (p = 0.0005). Guanosine-5'-Phosphovanadate 126-129 heme oxygenase 1 Homo sapiens 90-94 33919311-4 2021 The results of voxel-based multiple regression analysis showed that blood levels of CypA, HO-1, and IRE1 were correlated with GMV on brain magnetic resonance imaging (MRI) in the entire population (p = 0.0005). Guanosine-5'-Phosphovanadate 126-129 endoplasmic reticulum to nucleus signaling 1 Homo sapiens 100-104 33919311-7 2021 HO-1 values increased with increasing GMV at the uncus (r = 0.307, p = 0.0008), lateral globus pallidus and putamen (r = 0.287, p = 0.002), and hippocampus (r = 0.197, p = 0.034). Guanosine-5'-Phosphovanadate 38-41 heme oxygenase 1 Homo sapiens 0-4 33919311-8 2021 IRE1 values decreased with increasing GMV at the uncus (r = -0.239, p = 0.010) and lateral globus pallidus and putamen (r = -0.335, p = 0.0002). Guanosine-5'-Phosphovanadate 38-41 endoplasmic reticulum to nucleus signaling 1 Homo sapiens 0-4 33836266-6 2021 Results showed no concurrent association between GMV in IPS and math performance, but a concurrent association between GMV in left MTG/STG and multiplication skill at T1. Guanosine-5'-Phosphovanadate 119-122 serine protease 3 Homo sapiens 131-134 33935941-7 2021 The GMV of the entire contralesional insula was also larger in insular glioma patients with IDH mutation than in patients with wild-type IDH. Guanosine-5'-Phosphovanadate 4-7 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 92-95 33935941-7 2021 The GMV of the entire contralesional insula was also larger in insular glioma patients with IDH mutation than in patients with wild-type IDH. Guanosine-5'-Phosphovanadate 4-7 isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens 137-140 33836266-6 2021 Results showed no concurrent association between GMV in IPS and math performance, but a concurrent association between GMV in left MTG/STG and multiplication skill at T1. Guanosine-5'-Phosphovanadate 119-122 chromosome 6 open reading frame 15 Homo sapiens 135-138 33836266-9 2021 Whereas higher levels of GMV in left IPS at T1 predicted larger subtraction gains, higher levels of GMV in left MTG/STG predicted smaller gains. Guanosine-5'-Phosphovanadate 100-103 serine protease 3 Homo sapiens 112-115 33836266-9 2021 Whereas higher levels of GMV in left IPS at T1 predicted larger subtraction gains, higher levels of GMV in left MTG/STG predicted smaller gains. Guanosine-5'-Phosphovanadate 100-103 chromosome 6 open reading frame 15 Homo sapiens 116-119 33836266-10 2021 GMV in left MTG/STG did not predict longitudinal gains in multiplication skill. Guanosine-5'-Phosphovanadate 0-3 serine protease 3 Homo sapiens 12-15 33548051-8 2021 Serum leptin levels (pg/mL) had positively correlations with GMV in right medial OFC, left medial OFC, right lateral OFC, and left anterior cingulate cortex. Guanosine-5'-Phosphovanadate 61-64 leptin Homo sapiens 6-12 32710107-4 2021 We found that the individuals with higher OXTR-PRSASDs had lower RD and significantly smaller GMV in the right posterior insula and putamen. Guanosine-5'-Phosphovanadate 94-97 oxytocin receptor Homo sapiens 42-46 33205159-7 2021 Similar age-sex interactions were also observed for GMV and WMV. Guanosine-5'-Phosphovanadate 52-55 renin binding protein Homo sapiens 8-11 32710107-5 2021 The GMV of this region showed a positive correlation with RD and a mediation effect on the association between OXTR-PRSASDs and RD. Guanosine-5'-Phosphovanadate 4-7 oxytocin receptor Homo sapiens 111-115 32710107-8 2021 These findings highlight a possible neural pathway by which the common variants in the OXTR gene associated with ASDs may jointly impact the GMV of the right posterior insula and putamen and further affect the personality trait of RD. Guanosine-5'-Phosphovanadate 141-144 oxytocin receptor Homo sapiens 87-91 33051437-5 2020 We investigated the regions in which GMV changed between Tp1 and Tp2, Tp2 and Tp3, and Tp1 and Tp3 using voxel-based morphometry. Guanosine-5'-Phosphovanadate 37-40 transition protein 1 Homo sapiens 57-60 33489880-9 2020 Conclusions: An increase in WMLs and loss of GMV were observed in patients with metastatic NSCLC undergoing long-term EGFR-TKI treatment. Guanosine-5'-Phosphovanadate 45-48 epidermal growth factor receptor Homo sapiens 118-122 32864880-5 2020 In both groups, we found a positive correlation between 5-HT1A R binding potential and GMV in a region dependent manner. Guanosine-5'-Phosphovanadate 87-90 5-hydroxytryptamine receptor 1A Homo sapiens 56-62 33051437-5 2020 We investigated the regions in which GMV changed between Tp1 and Tp2, Tp2 and Tp3, and Tp1 and Tp3 using voxel-based morphometry. Guanosine-5'-Phosphovanadate 37-40 transition protein 2 Homo sapiens 65-68 33051437-7 2020 GMV increase in the left superior and inferior temporal gyrus during Tp1-Tp2 was associated with improvement in psychotic symptoms (P < 0.025). Guanosine-5'-Phosphovanadate 0-3 transition protein 1 Homo sapiens 69-72 33051437-7 2020 GMV increase in the left superior and inferior temporal gyrus during Tp1-Tp2 was associated with improvement in psychotic symptoms (P < 0.025). Guanosine-5'-Phosphovanadate 0-3 transition protein 2 Homo sapiens 73-76 33051437-8 2020 GMV increase in the left hippocampus was associated with improvement of depressive symptoms in Tp2-Tp3 (P < 0.05). Guanosine-5'-Phosphovanadate 0-3 transition protein 2 Homo sapiens 95-98 32447184-9 2020 The SIRT1-rs12415800 polymorphism may be associated with the changes of GMV in MDD patients. Guanosine-5'-Phosphovanadate 72-75 sirtuin 1 Homo sapiens 4-9 32621781-7 2020 LPR and MPR subgroups displayed larger GMV in the right inferior temporal gyrus than did the HPR subgroup. Guanosine-5'-Phosphovanadate 39-42 progesterone receptor membrane component 1 Homo sapiens 8-11 32240562-8 2020 We analyzed the results of a phase I/II study of a tag-7 gene-modified tumor cells-based vaccine (GMV) in patients with malignant melanoma (MM) or renal cell carcinoma (RCC) with biomarker analysis of immunosuppressive factors (ISFs) production by their tumor cells. Guanosine-5'-Phosphovanadate 98-101 peptidoglycan recognition protein 1 Homo sapiens 51-56 32240562-27 2020 CONCLUSION: GMV showed high results in carefully selected patients with low ISF (TGF-beta1, IL-10, and VEGF) production. Guanosine-5'-Phosphovanadate 12-15 transforming growth factor beta 1 Homo sapiens 81-90 32240562-27 2020 CONCLUSION: GMV showed high results in carefully selected patients with low ISF (TGF-beta1, IL-10, and VEGF) production. Guanosine-5'-Phosphovanadate 12-15 interleukin 10 Homo sapiens 92-97 32240562-27 2020 CONCLUSION: GMV showed high results in carefully selected patients with low ISF (TGF-beta1, IL-10, and VEGF) production. Guanosine-5'-Phosphovanadate 12-15 vascular endothelial growth factor A Homo sapiens 103-107 32387173-8 2020 Present results support the role of leptin in predicting GMV and CT recovery during the first month of abstinence in alcohol-dependent patients. Guanosine-5'-Phosphovanadate 57-60 leptin Homo sapiens 36-42 30991302-7 2019 Even though the APOE-epsilon4 allele load did not exert a direct impact on any cognitive measures, it reversed the relationships between GMv and cognitive performance in a highly symmetrical topological pattern. Guanosine-5'-Phosphovanadate 137-140 apolipoprotein E Homo sapiens 16-20 32378710-5 2020 Whole-brain regression analyses and prediction analyses showed that higher dispositional hope was stably associated with greater GMV in the left supplementary motor area (SMA). Guanosine-5'-Phosphovanadate 129-132 survival of motor neuron 1, telomeric Homo sapiens 171-174 31278861-7 2020 The associations between altered GMV with dopamine transporter (DAT) results and the level of CSF proteins were assessed. Guanosine-5'-Phosphovanadate 33-36 solute carrier family 6 member 3 Homo sapiens 42-62 31278861-7 2020 The associations between altered GMV with dopamine transporter (DAT) results and the level of CSF proteins were assessed. Guanosine-5'-Phosphovanadate 33-36 solute carrier family 6 member 3 Homo sapiens 64-67 30617779-6 2019 The results showed that shyness was significantly, negatively associated with FA, WMV and GMV in a cluster that included the dACC (dorsal anterior cingulate cortex) and the MCC (middle cingulate cortex) and was significantly positively associated with the GMV in the IPL (inferior parietal lobule), an effect that may have been related to the weaker ability to regulate emotion in these participants and their state of being overly worried about others" evaluations. Guanosine-5'-Phosphovanadate 90-93 Acetyl-CoA carboxylase Drosophila melanogaster 125-129 31071720-5 2019 Furthermore, as a result of examining the relationship between GMV in the left OFC and psychiatric symptoms in CM, we observed a negative association with insecure attachment style and also confirmed the mediation effect of left-OFC GMV reduction on the relationship between OXTR methylation and insecure attachment style. Guanosine-5'-Phosphovanadate 63-66 oxytocin receptor Homo sapiens 275-279 31071720-5 2019 Furthermore, as a result of examining the relationship between GMV in the left OFC and psychiatric symptoms in CM, we observed a negative association with insecure attachment style and also confirmed the mediation effect of left-OFC GMV reduction on the relationship between OXTR methylation and insecure attachment style. Guanosine-5'-Phosphovanadate 233-236 oxytocin receptor Homo sapiens 275-279 30415067-10 2019 The GMV of the left posterior cerebellum (from cerebellum crus to lobule VIII) was significantly positively correlated with SWE, as evidenced by the results of whole-brain and cerebellum-specific VBM analyses. Guanosine-5'-Phosphovanadate 4-7 cytochrome c oxidase subunit 8A Homo sapiens 73-77 32655362-2 2020 Recent studies have reported specific effects of kinectin 1 gene (KTN1) variants on the putamen GMV. Guanosine-5'-Phosphovanadate 96-99 kinectin 1 Homo sapiens 49-59 32655362-2 2020 Recent studies have reported specific effects of kinectin 1 gene (KTN1) variants on the putamen GMV. Guanosine-5'-Phosphovanadate 96-99 kinectin 1 Homo sapiens 66-70 32204972-5 2020 DAT availability was significantly positively correlated with GMV in the left middle frontal lobe (r = 0.58, P < 0.005), the GMV being significantly reduced in the patients with schizophrenia (0.45 +- 0.10 vs. 0.49 +- 0.07, P < 0.005). Guanosine-5'-Phosphovanadate 62-65 solute carrier family 6 member 3 Homo sapiens 0-3 32204972-5 2020 DAT availability was significantly positively correlated with GMV in the left middle frontal lobe (r = 0.58, P < 0.005), the GMV being significantly reduced in the patients with schizophrenia (0.45 +- 0.10 vs. 0.49 +- 0.07, P < 0.005). Guanosine-5'-Phosphovanadate 125-128 solute carrier family 6 member 3 Homo sapiens 0-3 30612340-6 2020 These findings suggest that GMV compromise in the early stages of PD may be a predisposing factor for cognitive decline of COMT Val/Val homozygotes. Guanosine-5'-Phosphovanadate 28-31 catechol-O-methyltransferase Homo sapiens 123-127 31967977-6 2020 The increase in GMV and reduction in CSFV were significantly correlated with serum GH/IGF-1 levels (p<0.05). Guanosine-5'-Phosphovanadate 16-19 growth hormone 1 Homo sapiens 83-85 31967977-6 2020 The increase in GMV and reduction in CSFV were significantly correlated with serum GH/IGF-1 levels (p<0.05). Guanosine-5'-Phosphovanadate 16-19 insulin like growth factor 1 Homo sapiens 86-91 31967977-7 2020 VBM showed significant correlations of the GMV/WMV alteration pattern between GH-PA vs HCs and GH-PA vs NonFun-PA and widespread bilateral clusters of significantly increased GMV and WMV in GH-PA (pFDR<0.05). Guanosine-5'-Phosphovanadate 43-46 growth hormone 1 Homo sapiens 78-80 31967977-7 2020 VBM showed significant correlations of the GMV/WMV alteration pattern between GH-PA vs HCs and GH-PA vs NonFun-PA and widespread bilateral clusters of significantly increased GMV and WMV in GH-PA (pFDR<0.05). Guanosine-5'-Phosphovanadate 43-46 growth hormone 1 Homo sapiens 95-97 31967977-7 2020 VBM showed significant correlations of the GMV/WMV alteration pattern between GH-PA vs HCs and GH-PA vs NonFun-PA and widespread bilateral clusters of significantly increased GMV and WMV in GH-PA (pFDR<0.05). Guanosine-5'-Phosphovanadate 43-46 growth hormone 1 Homo sapiens 95-97 30794041-6 2019 Additionally, GMV in both the bilateral S1 and the left SMA was positively correlated with the time span after the injury. Guanosine-5'-Phosphovanadate 14-17 survival of motor neuron 1, telomeric Homo sapiens 56-59 31105606-5 2019 Serum NGF was significantly correlated to GMV in the left prefrontal lobe, the left midcingulate cortex, and the brainstem in schizophrenia patients. Guanosine-5'-Phosphovanadate 42-45 nerve growth factor Homo sapiens 6-9 31105606-8 2019 In a conjunction analysis, GMV in the left midcingulate cortex (MCC) appears negatively correlated to NGF serum levels in the group of schizophrenia patients and also to be reduced compared to healthy controls. Guanosine-5'-Phosphovanadate 27-30 nerve growth factor Homo sapiens 102-105 30894870-6 2019 This is the first study to report that Hi-AVH subjects" baseline brain functional features are influenced by their COMT genotypes and that the COMT-met genotype subjects exhibit better responses to dopamine antagonists but have more widespread GMV and gFCD reduction than subjects with the COMT-val genotype. Guanosine-5'-Phosphovanadate 244-247 catechol-O-methyltransferase Homo sapiens 143-147 30894870-6 2019 This is the first study to report that Hi-AVH subjects" baseline brain functional features are influenced by their COMT genotypes and that the COMT-met genotype subjects exhibit better responses to dopamine antagonists but have more widespread GMV and gFCD reduction than subjects with the COMT-val genotype. Guanosine-5'-Phosphovanadate 244-247 catechol-O-methyltransferase Homo sapiens 143-147 29433615-9 2018 CONCLUSIONS: Our findings suggest that the DAT1-related GMV alterations in the posterior cortical regions may contribute to visual memory performance in children with ADHD. Guanosine-5'-Phosphovanadate 56-59 solute carrier family 6 member 3 Homo sapiens 43-47 30255962-9 2018 These findings bring novel information about specific cognitive abilities in SCA7 patients, particularly verbal memory and fluency, and their relation with GMV variations in circumscribed brain regions, including association cortices known to have functional relationships with the cerebellum. Guanosine-5'-Phosphovanadate 156-159 ataxin 7 Homo sapiens 77-81 30408626-7 2018 Within the FXS group, lower FMRP levels were associated with less GMV in several regions including cerebellum and gyrus rectus, and less white matter volume (WMV) in pregenual cingulate, middle frontal gyrus, and other regions. Guanosine-5'-Phosphovanadate 66-69 fragile X messenger ribonucleoprotein 1 Homo sapiens 28-32 30005610-8 2018 More importantly, the GMV of the SMA, SFG, and precentral gyrus in the left hemisphere was not only significantly negatively correlated with the hallucination severity but also significantly positively correlated with the RSS. Guanosine-5'-Phosphovanadate 22-25 survival of motor neuron 1, telomeric Homo sapiens 33-36 30036781-8 2018 Relative to nPD group, dPD group exhibited GMV reduction in the left Crus I, while aPD group showed GMV reduction in the tonsil and the right lobule VIII. Guanosine-5'-Phosphovanadate 43-46 dachs Drosophila melanogaster 23-26 30005610-11 2018 Also, the GMV of the left SMA, SFG, and precentral gyrus may be the common substrates underlying both hallucination induction and the RSS in people with schizophrenia. Guanosine-5'-Phosphovanadate 10-13 survival of motor neuron 1, telomeric Homo sapiens 26-29 29605385-4 2018 RESULTS: We found APOE-epsilon4 additive GMv reductions in the right hippocampus, caudate, precentral gyrus, and cerebellar crus. Guanosine-5'-Phosphovanadate 41-44 apolipoprotein E Homo sapiens 18-22 29605385-7 2018 DISCUSSION: Our data indicate that APOE-epsilon4 exerts additive effects on GMv in regions relevant for Alzheimer"s disease pathophysiology already in healthy individuals. Guanosine-5'-Phosphovanadate 76-79 apolipoprotein E Homo sapiens 35-39 29113872-5 2018 Moreover, two present scales (Present-Hedonistic and Present-Fatalistic TPs) were positively correlated with the GMV of regions in MTG and precuneus, respectively. Guanosine-5'-Phosphovanadate 113-116 serine protease 3 Homo sapiens 131-134 29550938-3 2018 Here we investigated the relationship between 5-HT1A receptor binding and GMV in 40 healthy controls (HCs) and, for the first time, 47 antidepressant-free MDD patients using Voxel-Based Morphometry and [11C]WAY100635 Positron Emission Tomography. Guanosine-5'-Phosphovanadate 74-77 5-hydroxytryptamine receptor 1A Homo sapiens 46-61 29550938-6 2018 In the HCs group, we found overall a positive correlation between terminal field 5-HT1A receptor binding and GMV, which reached statistical significance in regions such as hippocampus, insula, orbital prefrontal cortex, and parietal lobe. Guanosine-5'-Phosphovanadate 109-112 5-hydroxytryptamine receptor 1A Homo sapiens 81-96 29550938-7 2018 We observed a trend towards inverse correlation between raphe 5-HT1A autoreceptor binding and anterior cingulate GMV in both groups, and a statistically significant positive correlation between raphe 5-HT1A binding and temporal GMV in MDD. Guanosine-5'-Phosphovanadate 113-116 5-hydroxytryptamine receptor 1A Homo sapiens 62-68 29550938-7 2018 We observed a trend towards inverse correlation between raphe 5-HT1A autoreceptor binding and anterior cingulate GMV in both groups, and a statistically significant positive correlation between raphe 5-HT1A binding and temporal GMV in MDD. Guanosine-5'-Phosphovanadate 228-231 5-hydroxytryptamine receptor 1A Homo sapiens 200-206 29550938-8 2018 Analysis of covariance at the voxel-level revealed a trend towards interaction between diagnosis and raphe 5-HT1A binding in predicting GMV in cerebellum and supramarginal gyrus (higher correlation in HCs compared with MDD). Guanosine-5'-Phosphovanadate 136-139 5-hydroxytryptamine receptor 1A Homo sapiens 107-113 29550938-9 2018 Our results replicated previous findings in the normative brain, but did not extend them to the brain in MDD, and indicated a trend towards dissociation between MDD and HCs in the relationship of raphe 5-HT1A binding with postsynaptic GMV. Guanosine-5'-Phosphovanadate 235-238 5-hydroxytryptamine receptor 1A Homo sapiens 202-208 29899731-3 2018 In this work, using a cohort of 120 de novo PD patients with preserved cognition from the Parkinson"s Progression Markers Initiative (PPMI) database, we found that patients who were homozygous for MAPT H1 had less gray matter volume (GMV) and greater 1-year GMV loss than patients without this genetic profile. Guanosine-5'-Phosphovanadate 234-237 microtubule associated protein tau Homo sapiens 197-201 29899731-5 2018 Our findings suggest that early GMV loss in MAPT H1H1 PD patients increases their risk to develop cognitive decline. Guanosine-5'-Phosphovanadate 32-35 microtubule associated protein tau Homo sapiens 44-48 28921389-6 2018 We found significantly increased GMV in the right superior temporal gyrus, right inferior parietal lobule (IPL)/supramarginal gyrus (SMG), and left middle occipital gyrus. Guanosine-5'-Phosphovanadate 33-36 small nuclear ribonucleoprotein polypeptide G Homo sapiens 133-136 28078547-3 2018 Voxel-based morphometry was applied to analyze the main and interaction effects of ZNF804A rs1344706 and COMT rs4680 on brain GMV in 274 healthy young human subjects. Guanosine-5'-Phosphovanadate 126-129 zinc finger protein 804A Homo sapiens 83-90 28078547-4 2018 The GMV of the left dorsolateral prefrontal cortex (DLPFC) showed a significant COMT rs4680 x ZNF804A rs1344706 interaction, manifesting as an inverted U-shape modulation by the presumed dopamine signaling. Guanosine-5'-Phosphovanadate 4-7 catechol-O-methyltransferase Homo sapiens 80-84 28078547-6 2018 In COMT Val/Val homozygotes, however, the ZNF804A TG heterozygotes exhibited smaller GMV in the left DLPFC than GG homozygotes and comparable GMV with TT homozygotes. Guanosine-5'-Phosphovanadate 85-88 zinc finger protein 804A Homo sapiens 42-49 28078547-6 2018 In COMT Val/Val homozygotes, however, the ZNF804A TG heterozygotes exhibited smaller GMV in the left DLPFC than GG homozygotes and comparable GMV with TT homozygotes. Guanosine-5'-Phosphovanadate 142-145 zinc finger protein 804A Homo sapiens 42-49 28078547-4 2018 The GMV of the left dorsolateral prefrontal cortex (DLPFC) showed a significant COMT rs4680 x ZNF804A rs1344706 interaction, manifesting as an inverted U-shape modulation by the presumed dopamine signaling. Guanosine-5'-Phosphovanadate 4-7 zinc finger protein 804A Homo sapiens 94-101 28078547-7 2018 These findings suggest that ZNF804A affects the GMV of the prefrontal cortex by interacting with COMT, which may improve our understanding of neurobiological effect of ZNF804A and its association with schizophrenia. Guanosine-5'-Phosphovanadate 48-51 zinc finger protein 804A Homo sapiens 28-35 28078547-5 2018 In COMT Met-allele carriers, the ZNF804A TG heterozygotes showed greater GMV in the left DLPFC than both GG and TT homozygotes. Guanosine-5'-Phosphovanadate 73-76 catechol-O-methyltransferase Homo sapiens 3-7 28078547-7 2018 These findings suggest that ZNF804A affects the GMV of the prefrontal cortex by interacting with COMT, which may improve our understanding of neurobiological effect of ZNF804A and its association with schizophrenia. Guanosine-5'-Phosphovanadate 48-51 catechol-O-methyltransferase Homo sapiens 97-101 28078547-5 2018 In COMT Met-allele carriers, the ZNF804A TG heterozygotes showed greater GMV in the left DLPFC than both GG and TT homozygotes. Guanosine-5'-Phosphovanadate 73-76 zinc finger protein 804A Homo sapiens 33-40 28078547-7 2018 These findings suggest that ZNF804A affects the GMV of the prefrontal cortex by interacting with COMT, which may improve our understanding of neurobiological effect of ZNF804A and its association with schizophrenia. Guanosine-5'-Phosphovanadate 48-51 zinc finger protein 804A Homo sapiens 168-175 29434564-9 2017 Moreover, in the patients, we found a negative relationship between serum prolactin levels and the GMV of the left hippocampus and right IFC, whereas a positive relationship was found between the GMV of the left hippocampus and serum levels of estradiol and luteinizing hormone. Guanosine-5'-Phosphovanadate 99-102 prolactin Homo sapiens 74-83 28137305-7 2017 Importantly, a higher relative ratio of apoE4 over apoE3 was associated with GMV loss in the right posterior cingulate and with reduced CMRgl bilaterally in the anterior cingulate and in the right hippocampal area. Guanosine-5'-Phosphovanadate 77-80 apolipoprotein E Homo sapiens 40-45 27664968-7 2017 Mediation analysis revealed that the GMV of the left lateral FP mediated the association between COMT polymorphism and interference resolution in males. Guanosine-5'-Phosphovanadate 37-40 catechol-O-methyltransferase Homo sapiens 97-101 27664968-8 2017 These findings provide a gene-anatomy-cognition pathway to describe how COMT Val158Met polymorphism affects interference resolution capacity via modulating the prefrontal GMV in healthy male subjects. Guanosine-5'-Phosphovanadate 171-174 catechol-O-methyltransferase Homo sapiens 72-76 28763717-9 2017 Patients had decreased GMV in the superior/middle temporal gyrus (STG/MTG), pulvinar, and superior frontal gyrus after correction for age and BMI, and in the STG/MTG, middle frontal gyrus, and cingulate after correction for age. Guanosine-5'-Phosphovanadate 23-26 chromosome 6 open reading frame 15 Homo sapiens 66-69 28763717-10 2017 A correlational group difference was detected for body dissatisfaction and GMV in the STG. Guanosine-5'-Phosphovanadate 75-78 chromosome 6 open reading frame 15 Homo sapiens 86-89 28763717-11 2017 Our findings suggest that decreased GMV in the STG is related to body dissatisfaction that could come from impaired visuospatial perception, together with GMV decreases in several regions, which may be involved in development of AN. Guanosine-5'-Phosphovanadate 36-39 chromosome 6 open reading frame 15 Homo sapiens 47-50 26576742-8 2017 This reduced GMV was modulated by COMT polymorphism; Met-carriers exhibited smaller striatal GMV than the Val/Val genotype. Guanosine-5'-Phosphovanadate 13-16 catechol-O-methyltransferase Homo sapiens 34-38 26576742-8 2017 This reduced GMV was modulated by COMT polymorphism; Met-carriers exhibited smaller striatal GMV than the Val/Val genotype. Guanosine-5'-Phosphovanadate 93-96 catechol-O-methyltransferase Homo sapiens 34-38 26576742-9 2017 CONCLUSIONS: Contrasting with previous findings in Caucasians, the COMT Met allele was associated with striatal GMV alterations in Japanese children with ADHD. Guanosine-5'-Phosphovanadate 112-115 catechol-O-methyltransferase Homo sapiens 67-71 28377881-4 2017 Compared with healthy controls, right-lesion patients demonstrated GMV increase (P < 0.05, voxel-wise false discovery rate correction) in the bilateral paracentral lobule (PCL) and supplementary motor area (SMA) and the right middle occipital gyrus (MOG); while left-lesion patients did not exhibit GMV difference under the same threshold. Guanosine-5'-Phosphovanadate 67-70 survival of motor neuron 1, telomeric Homo sapiens 210-213 28377881-6 2017 However, the motor recovery was correlated with the GMV increase in the bilateral SMA in right-lesion patients. Guanosine-5'-Phosphovanadate 52-55 survival of motor neuron 1, telomeric Homo sapiens 82-85 28377881-8 2017 The GMV increase in the SMA may facilitate motor recovery in subcortical stroke patients. Guanosine-5'-Phosphovanadate 4-7 survival of motor neuron 1, telomeric Homo sapiens 24-27 28220826-4 2017 The results showed that artistic creativity was significantly negatively associated with the regional GMV of the supplementary motor area (SMA) and anterior cingulate cortex (ACC). Guanosine-5'-Phosphovanadate 102-105 survival of motor neuron 1, telomeric Homo sapiens 139-142 28137305-7 2017 Importantly, a higher relative ratio of apoE4 over apoE3 was associated with GMV loss in the right posterior cingulate and with reduced CMRgl bilaterally in the anterior cingulate and in the right hippocampal area. Guanosine-5'-Phosphovanadate 77-80 apolipoprotein E Homo sapiens 51-56 28137305-10 2017 CONCLUSIONS: Our study proposes a sex-dependent and age-dependent variation in plasma apoE isoform levels and concludes that peripheral apoE levels are associated with GMV, CMRgl and possibly cognitive performance in cognitively healthy individuals with a genetic predisposition to AD. Guanosine-5'-Phosphovanadate 168-171 apolipoprotein E Homo sapiens 136-140 28106551-7 2017 In APOE e4-carriers- but not in APOE e4-non-carriers- conscientiousness was negatively associated with total GMV. Guanosine-5'-Phosphovanadate 109-112 apolipoprotein E Homo sapiens 3-7 27779372-9 2017 CONCLUSIONS: The SORL1 gene rs1699102 polymorphism has been found to be associated with age-related cognitive decline and GMV reduction of the right middle temporal pole in older adults. Guanosine-5'-Phosphovanadate 122-125 sortilin related receptor 1 Homo sapiens 17-22 28106551-8 2017 In line with the hypothesis of antagonistic pleiotropy of the APOE e4 allele, this result suggests that young APOE e4-carriers with increased total GMV may particularly benefit from cognitive advantages and thus have a lower need to engage in conscientious behavior. Guanosine-5'-Phosphovanadate 148-151 apolipoprotein E Homo sapiens 62-66 28106551-8 2017 In line with the hypothesis of antagonistic pleiotropy of the APOE e4 allele, this result suggests that young APOE e4-carriers with increased total GMV may particularly benefit from cognitive advantages and thus have a lower need to engage in conscientious behavior. Guanosine-5'-Phosphovanadate 148-151 apolipoprotein E Homo sapiens 110-114 28106551-10 2017 Hence, young APOE e4-carriers with increased total GMV may be at a particularly high risk for LOAD. Guanosine-5'-Phosphovanadate 51-54 apolipoprotein E Homo sapiens 13-17 26918638-5 2016 Although the two groups did not generally differ in their hippocampal GMV, a reduction of GMV in the bilateral hippocampal CA3 region was significantly correlated with increased vestibulopathy-related clinical impairment. Guanosine-5'-Phosphovanadate 90-93 carbonic anhydrase 3 Homo sapiens 123-126 26498330-7 2016 Moreover, this rsFC was negatively correlated with the GMV of the right dACC. Guanosine-5'-Phosphovanadate 55-58 Acetyl-CoA carboxylase Drosophila melanogaster 72-76 27027249-8 2016 A mixed mediation and moderation analysis further revealed both a significant mediation effect of the GMV of the right FFA on the association between AVPR1A RS3 repeat polymorphisms and allocation sums and a significant moderation effect of sex (only in males) on the mediation effect. Guanosine-5'-Phosphovanadate 102-105 arginine vasopressin receptor 1A Homo sapiens 150-156 27027249-10 2016 These results suggest that the GMV of the right FFA may be a potential mediator whereby the genetic variants in AVPR1A RS3 affect altruistic behavior in healthy male subjects. Guanosine-5'-Phosphovanadate 31-34 arginine vasopressin receptor 1A Homo sapiens 112-118 25708696-8 2016 Subjects who carried more risk alleles and haplotypes of ZNF804A had greater GMV in the bilateral insular cortex, right temporal cortex and superior parietal cortex. Guanosine-5'-Phosphovanadate 77-80 zinc finger protein 804A Homo sapiens 57-64 25708696-9 2016 The interaction between heroin addiction and ZNF804A variants affected GMV in the left sensorimotor cortex. Guanosine-5'-Phosphovanadate 71-74 zinc finger protein 804A Homo sapiens 45-52 25708696-10 2016 Our findings revealed several ZNF804A variants that were significantly associated with the risk of heroin addiction, and these variants affected decision making and GMV in heroin abusers compared with controls. Guanosine-5'-Phosphovanadate 165-168 zinc finger protein 804A Homo sapiens 30-37