PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 30199284-4 2019 Because deoxyuridine diphosphate is synthesized by RNR, the simultaneous recruitment of TMPK and RNR to DNA damage sites is critical for preventing deoxyuridine triphosphate-mediated toxic repair. dUDP 8-32 deoxythymidylate kinase Homo sapiens 88-92 29857987-5 2018 On day 10.5 of gestation, the embryos were explanted and prepared for immunohistochemical studies, for the evaluation of gene expression by reverse transcription polymerase chain reaction and for TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end-labelling assay analysis. dUDP 249-253 DNA nucleotidylexotransferase Rattus norvegicus 201-238 25892501-3 2015 TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling assay showed apoptotic cells in testicular sections of translocation carrier. dUDP 53-57 DNA nucleotidylexotransferase Homo sapiens 0-3 27210771-8 2016 Ki67 staining confirmed growth of the grafted follicles and terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling assay revealed 100% of the follicles to be viable in both groups on day 7. dUDP 108-112 DNA nucleotidylexotransferase Homo sapiens 60-97 26621853-13 2016 Sera were harvested for estradiol (E2) analysis, and the ovaries were processed for hematoxylin and eosin (HE) staining, immunohistochemistry (IHC), TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labeling (TUNEL), RT-PCR and western blot. dUDP 202-206 DNA nucleotidylexotransferase Rattus norvegicus 154-191 29197543-8 2018 resulted in significant hyperthermia, oxidative stress and microgliosis (microglial differentiation into M1 phenotype) followed by pro-apoptotic changes and the induction of terminal deoxynucleotidyl transferase dUDP nick end labeling (TUNEL)-positive cells. dUDP 212-216 deoxynucleotidyltransferase, terminal Mus musculus 174-211 27838218-5 2017 Sperm DNA fragmentation (SDF) was evaluated using TdT-mediated dUDP nick-end labelling (TUNEL) assay. dUDP 63-67 DNA nucleotidylexotransferase Homo sapiens 50-53 25892501-3 2015 TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling assay showed apoptotic cells in testicular sections of translocation carrier. dUDP 53-57 DNA nucleotidylexotransferase Homo sapiens 5-42 25796551-11 2015 Ovarian GnRH receptor (GnRHR), AMH and CD34 were visualized by IHC, and apoptosis was evaluated using TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labeling (TUNEL). dUDP 155-159 DNA nucleotidylexotransferase Homo sapiens 102-105 25796551-11 2015 Ovarian GnRH receptor (GnRHR), AMH and CD34 were visualized by IHC, and apoptosis was evaluated using TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labeling (TUNEL). dUDP 155-159 DNA nucleotidylexotransferase Homo sapiens 107-144 21831832-3 2011 Our spectroscopy and transient kinetics results on human dUTPase mutants combined with previous structural studies indicate that (i) H-bond interactions between the gamma-phosphate and the P-loop-like motif V promote the catalytically competent conformation of the reaction center at the alpha-phosphate group; (ii) these interactions accelerate the chemical step of the kinetic cycle and that (iii) hydrolysis occurs very slowly or not at all in the absence of the gamma-phosphate--motif V interactions, i.e., in dUDP, dUDP.BeFx, or in the motif V-deleted mutant. dUDP 514-518 Deoxyuridine triphosphatase Drosophila melanogaster 57-64 22019617-3 2011 DNA fragmentation was evaluated by TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling assay. dUDP 88-92 DNA nucleotidylexotransferase Homo sapiens 35-38 22019617-3 2011 DNA fragmentation was evaluated by TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling assay. dUDP 88-92 DNA nucleotidylexotransferase Homo sapiens 40-77 25773528-5 2015 TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling assay was carried out to detect the oocyte apoptosis; immunocytochemical staining and quantitative real time-polymerase chain reaction detected the expression of c-kit and Forkhead box O3a (Foxo3a); Western blot was performed to detect the expression of Sohlh2, C-kit, saerine/threonine kinases (Akt1) and Foxo3a. dUDP 53-57 deoxynucleotidyltransferase, terminal Mus musculus 0-3 25773528-5 2015 TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling assay was carried out to detect the oocyte apoptosis; immunocytochemical staining and quantitative real time-polymerase chain reaction detected the expression of c-kit and Forkhead box O3a (Foxo3a); Western blot was performed to detect the expression of Sohlh2, C-kit, saerine/threonine kinases (Akt1) and Foxo3a. dUDP 53-57 deoxynucleotidyltransferase, terminal Mus musculus 5-42 25779020-3 2015 Apoptosis assessment was conducted by analysis of DNA laddering, TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end-labelling and caspase-3/7 activity. dUDP 118-122 deoxynucleotidyltransferase, terminal Mus musculus 65-68 25779020-3 2015 Apoptosis assessment was conducted by analysis of DNA laddering, TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end-labelling and caspase-3/7 activity. dUDP 118-122 deoxynucleotidyltransferase, terminal Mus musculus 70-107 21831832-3 2011 Our spectroscopy and transient kinetics results on human dUTPase mutants combined with previous structural studies indicate that (i) H-bond interactions between the gamma-phosphate and the P-loop-like motif V promote the catalytically competent conformation of the reaction center at the alpha-phosphate group; (ii) these interactions accelerate the chemical step of the kinetic cycle and that (iii) hydrolysis occurs very slowly or not at all in the absence of the gamma-phosphate--motif V interactions, i.e., in dUDP, dUDP.BeFx, or in the motif V-deleted mutant. dUDP 520-524 Deoxyuridine triphosphatase Drosophila melanogaster 57-64 19851015-3 2009 In the presence of dUDP, the enzyme produced thin stacked orthorhombic P222 crystals with unit-cell parameters a = 81.0, b = 96.2, c = 132.8 A. T7-histidine-tagged Mu-22 dUTPase formed thin stacked rectangular crystals. dUDP 19-23 Deoxyuridine triphosphatase Drosophila melanogaster 170-177 21507722-5 2011 DNA damage (fragmentation and denaturation) was evaluated in the sperm head in the context of birefringence, both total (SHBF-T) and partial (SHBF-P), by terminal deoxyribonucleotidyl transferase (TdT)-mediated dUDP nick-end labelling assay and acridine orange fluorescence, respectively. dUDP 211-215 DNA nucleotidylexotransferase Homo sapiens 154-195 21269879-5 2011 Sperm cells were analysed by fluorescence in-situ hybridization, using probes specific for chromosomes 13, 21, 18, X and Y, and by TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling assay. dUDP 184-188 DNA nucleotidylexotransferase Homo sapiens 131-134 21269879-5 2011 Sperm cells were analysed by fluorescence in-situ hybridization, using probes specific for chromosomes 13, 21, 18, X and Y, and by TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling assay. dUDP 184-188 DNA nucleotidylexotransferase Homo sapiens 136-173 20864414-5 2010 Sperm DNA damage was evaluated by TdT-mediated dUDP nick-end labelling assay. dUDP 47-51 DNA nucleotidylexotransferase Homo sapiens 34-37 21613234-6 2011 Sperm DNA fragmentation was evaluated by terminal deoxyribonucleotidyl transferase (TdT)-mediated dUDP nick-end labelling (TUNEL) assay, and sperm BPDE-DNA adducts were measured by immunofluorescent assay using flow cytometry. dUDP 98-102 DNA nucleotidylexotransferase Homo sapiens 41-82 21613234-6 2011 Sperm DNA fragmentation was evaluated by terminal deoxyribonucleotidyl transferase (TdT)-mediated dUDP nick-end labelling (TUNEL) assay, and sperm BPDE-DNA adducts were measured by immunofluorescent assay using flow cytometry. dUDP 98-102 DNA nucleotidylexotransferase Homo sapiens 84-87 21233018-2 2011 Sperm samples from 12 infertile patients were studied by fluorescence in-situ hybridization for chromosomes X, Y, 13, 18 and 21 and by TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling. dUDP 188-192 DNA nucleotidylexotransferase Homo sapiens 135-138 21233018-2 2011 Sperm samples from 12 infertile patients were studied by fluorescence in-situ hybridization for chromosomes X, Y, 13, 18 and 21 and by TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling. dUDP 188-192 DNA nucleotidylexotransferase Homo sapiens 140-177 19712565-2 2009 TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) assay was used to assess fragmentation, and DNA decondensation was measured with either chromomycin or aniline blue staining. dUDP 53-57 DNA nucleotidylexotransferase Homo sapiens 0-3 19712565-2 2009 TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) assay was used to assess fragmentation, and DNA decondensation was measured with either chromomycin or aniline blue staining. dUDP 53-57 DNA nucleotidylexotransferase Homo sapiens 5-42 17544982-2 2007 The interaction of Plasmodium falciparum dUTPase (PfdUTPase) with deoxyuridine derivatives (dU, dUMP, dUDP and dUpNHpp) has been studied thermodynamically by both isothermal titration and differential scanning calorimetry. dUDP 102-106 Deoxyuridine triphosphatase Drosophila melanogaster 41-48 17469058-2 2007 We used the acridine orange test (AOT) and the terminal deoxynucleotidyl transferase-mediated dUDP nick-end labeling (TUNEL) assay to assess the DNA status of sperm cells preserved with different lyophilization media. dUDP 94-98 DNA nucleotidylexotransferase Bos taurus 47-84 17452782-4 2007 The crystal structure of vaccinia virus dUTPase has been solved and the active site has been mapped by crystallographic analysis of the apo enzyme and of complexes with the substrate-analog dUMPNPP, with the product dUMP and with dUDP, which acts as an inhibitor. dUDP 230-234 Deoxyuridine triphosphatase Drosophila melanogaster 40-47 16574700-9 2006 Embryos cultured from E3.5+24 h in the suboptimal medium (Ham"s F10) induced significant but small increases in TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) positive cells. dUDP 165-169 deoxynucleotidyltransferase, terminal Mus musculus 112-115 16982656-3 2006 Chromatin parameters assessed included quantification of thiols, nuclear chromomycin A3 (CMA3) penetration, DNA breaks by TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) and ease of DNA dissociation by acridine orange (AO) staining. dUDP 175-179 DNA nucleotidylexotransferase Rattus norvegicus 122-125 16982656-3 2006 Chromatin parameters assessed included quantification of thiols, nuclear chromomycin A3 (CMA3) penetration, DNA breaks by TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) and ease of DNA dissociation by acridine orange (AO) staining. dUDP 175-179 DNA nucleotidylexotransferase Rattus norvegicus 127-164 16574987-7 2006 XBP-1 splicing and CHOP expression were observed within 8 h. After 24 h, increased activation of the ER stress-related proapoptotic molecule caspase-12 was observed along with an increase in caspase-3 activity and TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labeling (TUNEL) staining in exocrine acini. dUDP 267-271 X-box binding protein 1 Rattus norvegicus 0-5 16574987-7 2006 XBP-1 splicing and CHOP expression were observed within 8 h. After 24 h, increased activation of the ER stress-related proapoptotic molecule caspase-12 was observed along with an increase in caspase-3 activity and TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labeling (TUNEL) staining in exocrine acini. dUDP 267-271 caspase 12 Rattus norvegicus 141-151 16574700-9 2006 Embryos cultured from E3.5+24 h in the suboptimal medium (Ham"s F10) induced significant but small increases in TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) positive cells. dUDP 165-169 deoxynucleotidyltransferase, terminal Mus musculus 117-154 16467399-3 2006 TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) assays and Hoechst staining indicated that IFNgamma alone could not induce apoptosis of JAR and JEG-3 cells, but IFNgamma could enhance the sensitivity of JAR cells to etoposide-induced apoptosis. dUDP 53-57 DNA nucleotidylexotransferase Homo sapiens 0-3 16467399-3 2006 TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) assays and Hoechst staining indicated that IFNgamma alone could not induce apoptosis of JAR and JEG-3 cells, but IFNgamma could enhance the sensitivity of JAR cells to etoposide-induced apoptosis. dUDP 53-57 DNA nucleotidylexotransferase Homo sapiens 5-42 15901458-2 2005 Currently, the techniques of TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end (TUNEL) labelling for the detection of apoptosis, and differential staining for determining the ratio of inner cell mass (ICM) to trophectoderm (TE) cells, are used separately to assess embryo quality in a range of different species. dUDP 82-86 DNA nucleotidylexotransferase Bos taurus 29-32 15760954-3 2005 These cells were used for immunocytochemical analysis for Ki67, western blot analysis for proliferating cell nuclear antigen (PCNA) and human EGF receptor (HER1), and TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) assay. dUDP 220-224 DNA nucleotidylexotransferase Homo sapiens 172-209 15901458-2 2005 Currently, the techniques of TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end (TUNEL) labelling for the detection of apoptosis, and differential staining for determining the ratio of inner cell mass (ICM) to trophectoderm (TE) cells, are used separately to assess embryo quality in a range of different species. dUDP 82-86 DNA nucleotidylexotransferase Bos taurus 34-71 15285929-6 2004 DNA fragmentation analysis and TUNEL (terminal deoxynucleotidyl transferase [TdT]-mediated deoxyuridine diphosphate [dUTP] nick end labeling) staining showed a typical pattern of DNA laddering and DNA breaks staining, respectively, in wild-type p53-containing HepG2 cells after EPA treatment. dUDP 91-115 DNA nucleotidylexotransferase Homo sapiens 38-75 15364583-5 2004 The X-ray structure of the C.jejuni dUTPase in complex with the non-hydrolysable substrate analogue dUpNHp allows us to define the positions of three catalytically significant phosphate-binding magnesium ions and provides a starting point for a detailed understanding of the mechanism of dUTP/dUDP hydrolysis by dimeric dUTPases. dUDP 293-297 Deoxyuridine triphosphatase Drosophila melanogaster 36-43 15327392-7 2004 Challenge of Fah(-/-) mice on NTBC with HGA led to massive death of renal proximal tubular cells, with positive terminal deoxynucleotidyl transferase-mediated deoxyuridine diphosphate (dUDP) nick-end labeling (TUNEL) and DNA fragmentation assays, but hardly any cleavage of caspase-9 and caspase-3. dUDP 159-183 fumarylacetoacetate hydrolase Mus musculus 13-16 15327392-7 2004 Challenge of Fah(-/-) mice on NTBC with HGA led to massive death of renal proximal tubular cells, with positive terminal deoxynucleotidyl transferase-mediated deoxyuridine diphosphate (dUDP) nick-end labeling (TUNEL) and DNA fragmentation assays, but hardly any cleavage of caspase-9 and caspase-3. dUDP 185-189 fumarylacetoacetate hydrolase Mus musculus 13-16 15100385-4 2004 Sperm viability was estimated by eosin-nigrosin staining and by hypo-osmotic swelling test; apoptosis percentage was measured by the TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling technique. dUDP 186-190 DNA nucleotidylexotransferase Homo sapiens 133-136 15100385-4 2004 Sperm viability was estimated by eosin-nigrosin staining and by hypo-osmotic swelling test; apoptosis percentage was measured by the TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling technique. dUDP 186-190 DNA nucleotidylexotransferase Homo sapiens 138-175 15285929-6 2004 DNA fragmentation analysis and TUNEL (terminal deoxynucleotidyl transferase [TdT]-mediated deoxyuridine diphosphate [dUTP] nick end labeling) staining showed a typical pattern of DNA laddering and DNA breaks staining, respectively, in wild-type p53-containing HepG2 cells after EPA treatment. dUDP 91-115 DNA nucleotidylexotransferase Homo sapiens 77-80 12581879-7 2003 TdT-Mediated dUDP Nick End Labeling assay and Hoechst staining indicate that T3 rescues developing oligodendrocytes from death by apoptosis. dUDP 13-17 DNA nucleotidylexotransferase Homo sapiens 0-3 14665702-6 2004 The percentage of spermatozoa showing DNA fragmentation was also determined in 13 of these samples, by using the TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) reaction. dUDP 166-170 DNA nucleotidylexotransferase Homo sapiens 113-116 14665702-6 2004 The percentage of spermatozoa showing DNA fragmentation was also determined in 13 of these samples, by using the TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) reaction. dUDP 166-170 DNA nucleotidylexotransferase Homo sapiens 118-155 14725764-0 2004 The crystal structure of Trypanosoma cruzi dUTPase reveals a novel dUTP/dUDP binding fold. dUDP 72-76 Deoxyuridine triphosphatase Drosophila melanogaster 43-50 14725764-2 2004 We report here the X-ray structure of Trypanosoma cruzi dUTPase in its native conformation and as a complex with dUDP. dUDP 113-117 Deoxyuridine triphosphatase Drosophila melanogaster 56-63 10957629-2 2000 Seven crystal structures of feline immunodeficiency virus (FIV) dUTPase in three crystal forms have been determined, including complexes with substrate (dUTP), product (dUMP) or inhibitor (dUDP) bound. dUDP 189-193 Deoxyuridine triphosphatase Drosophila melanogaster 64-71 9084433-2 1997 Both A beta(25-35)- and staurosporine-induced death of these neurons appeared to involve apoptosis, as indicated using Hoechst 33342 and terminal dUDP nick end labeling staining, whereas NMDA-induced death appeared more complex. dUDP 146-150 amyloid beta precursor protein Rattus norvegicus 5-11 10657253-4 2000 The enzyme has proved to be a dimer by gel filtration and is able to hydrolyse both dUTP and dUDP quite efficiently, acting as a dUTP nucleotidohydrolase (dUTPase)-dUDP nucleotidohydrolase but has a limited capacity to act upon other nucleoside di- or triphosphates. dUDP 93-97 Deoxyuridine triphosphatase Drosophila melanogaster 155-162 9878436-8 1999 The positions of the inhibitor (the non-hydrolysable substrate analogue dUDP) and the metal ion in the complex are consistent with the location of the active centre established for trimeric dUTPase structures, in which subunit interfaces form three surface clefts lined with evolutionary conserved residues. dUDP 72-76 Deoxyuridine triphosphatase Drosophila melanogaster 190-197 9878436-10 1999 The viral enzyme undergoes a small conformational change in the uracil-binding beta-hairpin structure upon dUDP binding not observed in the other known dUTPase structures. dUDP 107-111 Deoxyuridine triphosphatase Drosophila melanogaster 152-159 8646539-0 1996 Crystal structure of the Escherichia coli dUTPase in complex with a substrate analogue (dUDP). dUDP 88-92 Deoxyuridine triphosphatase Drosophila melanogaster 42-49 8805593-4 1996 We report the first detailed atomic-resolution structure of a eukaryotic dUTPase, human dUTPase, and complexes with the uracil-containing deoxyribonucleotides, dUMP, dUDP and dUTP. dUDP 166-170 Deoxyuridine triphosphatase Drosophila melanogaster 73-80 8805593-4 1996 We report the first detailed atomic-resolution structure of a eukaryotic dUTPase, human dUTPase, and complexes with the uracil-containing deoxyribonucleotides, dUMP, dUDP and dUTP. dUDP 166-170 Deoxyuridine triphosphatase Drosophila melanogaster 88-95 8646539-1 1996 We have determined the structure of the homotrimeric dUTPase from Escherichia coli, completed with an inhibitor and substrate analogue, dUDP. dUDP 136-140 Deoxyuridine triphosphatase Drosophila melanogaster 53-60 8604980-9 1996 As a consequence of Tyr-93 derivatization, the Mg2+-dependent interaction between the substrate-analogue dUDP and E. coli dUTPase becomes impaired as shown by circular dichroism spectroscopy, here presented as a tool for monitoring ligand binding to the active site. dUDP 105-109 Deoxyuridine triphosphatase Drosophila melanogaster 122-129 32896475-4 2020 Apoptosis was analysed by TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) assay. dUDP 79-83 DNA nucleotidylexotransferase Homo sapiens 26-29 35400579-2 2022 DESIGN: Clinical data from 1339 couples undergoing 2759 IVF/ICSI cycles using autologous oocytes with a SDF test by TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) assay on their ejaculated spermatozoa were retrospectively evaluated. dUDP 169-173 DNA nucleotidylexotransferase Homo sapiens 116-119 35400579-2 2022 DESIGN: Clinical data from 1339 couples undergoing 2759 IVF/ICSI cycles using autologous oocytes with a SDF test by TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) assay on their ejaculated spermatozoa were retrospectively evaluated. dUDP 169-173 DNA nucleotidylexotransferase Homo sapiens 121-158 32942006-4 2020 DUD significantly suppressed A549 cell migration by reversing EMT. dUDP 0-3 IL2 inducible T cell kinase Homo sapiens 62-65 32942006-6 2020 Meanwhile, DUD inhibited the beta-catenin nuclear translocation by upregulating Axin and downregulating the expression of APC, CK1 and phosphorylation of GSK3beta, and simultaneously decreasing MMP9 and MMP13 expression. dUDP 11-14 catenin beta 1 Homo sapiens 29-41 32942006-8 2020 Furthermore, we used XAV939, an beta-catenin inhibitor, to verify the mechanism of DUD. dUDP 83-86 catenin beta 1 Homo sapiens 32-44 32942006-9 2020 These results suggested that DUD inhibited A549 cells migration by reversing EMT via Wnt/beta-catenin and PI3K/Akt signaling. dUDP 29-32 IL2 inducible T cell kinase Homo sapiens 77-80 32942006-9 2020 These results suggested that DUD inhibited A549 cells migration by reversing EMT via Wnt/beta-catenin and PI3K/Akt signaling. dUDP 29-32 catenin beta 1 Homo sapiens 89-101 32942006-9 2020 These results suggested that DUD inhibited A549 cells migration by reversing EMT via Wnt/beta-catenin and PI3K/Akt signaling. dUDP 29-32 AKT serine/threonine kinase 1 Homo sapiens 111-114 32896475-4 2020 Apoptosis was analysed by TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL) assay. dUDP 79-83 DNA nucleotidylexotransferase Homo sapiens 31-68 31391279-4 2019 This observation contrasts with the existence in T. brucei of a dimeric deoxyuridine 5"-triphosphate nucleotidohydrolase (dUTPase), an essential enzyme that can produce dUMP via the hydrolysis of dUTP/dUDP. dUDP 201-205 Deoxyuridine triphosphatase Drosophila melanogaster 122-129 30979611-3 2019 The main outcome measures were sDF measured by comet assay, TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL), sperm chromatin dispersion (SCD) or sperm chromatin structure assay. dUDP 113-117 DNA nucleotidylexotransferase Homo sapiens 60-63 30979611-3 2019 The main outcome measures were sDF measured by comet assay, TdT (terminal deoxynucleotidyl transferase)-mediated dUDP nick-end labelling (TUNEL), sperm chromatin dispersion (SCD) or sperm chromatin structure assay. dUDP 113-117 DNA nucleotidylexotransferase Homo sapiens 65-102