PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
30268883-1	2018	This study investigated the impact of pH on the migration of cadmium(II) ions (Cd2+) in relation to montmorillonite KSF colloids through a water-saturated sand column (WSSC).	Cadmium ion	61-72	CD2 molecule	Homo sapiens	79-82
30071432-1	2018	Cadmium(II) ion can affect the anode performance of bioelectrochemical systems (BES); however, how the presence of Cd2+ affect the extracellular electron transfer of anodic electrochemically active biofilms (EABs), the microbial viability and species composition of microorganism on the anode remain poorly understood.	Cadmium ion	0-11	CD2 molecule	Homo sapiens	115-118
26293698-1	2015	A novel cadmium(ii) based metal organic framework, [Cd(3-bpd)(SCN)2]n () where 3-bpd = 1,4-bis(3-pyridyl)-2,3-diaza-1,3-butadiene has been synthesized and characterized by elemental analysis, various spectroscopic techniques, TGA and single crystal X-ray diffraction analysis.	Cadmium ion	8-19	T-box transcription factor 1	Homo sapiens	226-229
30240204-3	2018	FJU-35 with coordinated solvent and formate in asymmetric mu3-eta1:eta2 coordination mode within the CdII-O-CdII chains is vulnerable to external attacks and is apt to collapse after activation, while FJU-36 with no coordinated solvent in the CdII-O-CdII chains but fully protected by the carboxylates from the ligands and the symmetric formate in the coordination mode mu3-eta2:eta2 is stable, and its activated sample shows efficient separation of C2H2/CH4 and C2H2/CO2 mixtures.	Cadmium ion	101-105	DNA polymerase iota	Homo sapiens	67-71
28925691-1	2017	Postsynthetic decoration of the Mn7, {MnIII MnII6}, core with CdII in the outer shell to form the next generation Mn13Cd6, {MnIII MnIII3MnII3  MnII6CdII6}, core-shell disc was achieved and confirmed by single-crystal X-ray diffraction.	Cadmium ion	62-66	HERC2 pseudogene 2	Homo sapiens	32-35
27476997-0	2017	Synthesis and crystal structures of cobalt(II), cadmium(II), and zinc(II) complexes of 4-nitro phenylcyanamide: enhancing the biological properties through bound to human serum albumin.	Cadmium ion	48-59	albumin	Homo sapiens	171-184
25233031-1	2015	Two new cadmium(II) complexes with the formula of CdL2(NCS)2 and CdL2(N3)2 (in which L is 2,2-dimethyl-N,N"-bis-(3-phenyl-allylidene)-propane-1,3-diamine) have been synthesized and characterized by elemental analysis, molar conductivity measurements, FT/IR, UV-Visible, (1)H and (13)C NMR spectra and X-ray studies.	Cadmium ion	8-19	cytosolic thiouridylase subunit 2	Homo sapiens	50-60
25233031-1	2015	Two new cadmium(II) complexes with the formula of CdL2(NCS)2 and CdL2(N3)2 (in which L is 2,2-dimethyl-N,N"-bis-(3-phenyl-allylidene)-propane-1,3-diamine) have been synthesized and characterized by elemental analysis, molar conductivity measurements, FT/IR, UV-Visible, (1)H and (13)C NMR spectra and X-ray studies.	Cadmium ion	8-19	Cornelia de Lange syndrome 2	Homo sapiens	50-54
25446093-6	2014	Consistent with this, a SR34b T-DNA insertion mutant (sr34b) was moderately sensitive to Cd, which had higher Cd(2+) uptake rate and accumulated Cd in greater amounts than wild-type.	Cadmium ion	110-116	RNA-binding (RRM/RBD/RNP motifs) family protein	Arabidopsis thaliana	24-29
25446093-6	2014	Consistent with this, a SR34b T-DNA insertion mutant (sr34b) was moderately sensitive to Cd, which had higher Cd(2+) uptake rate and accumulated Cd in greater amounts than wild-type.	Cadmium ion	110-116	RNA-binding (RRM/RBD/RNP motifs) family protein	Arabidopsis thaliana	54-59
23867017-6	2013	The expression of two ER stress markers NtBLP4 and NtPDI and an unfolded protein response related transcription factor NtbZIP60 were upregulated with Cd(2+) stress.	Cadmium ion	150-156	luminal-binding protein 4	Nicotiana tabacum	40-46
23867017-6	2013	The expression of two ER stress markers NtBLP4 and NtPDI and an unfolded protein response related transcription factor NtbZIP60 were upregulated with Cd(2+) stress.	Cadmium ion	150-156	bZIP transcription factor 60-like	Nicotiana tabacum	119-127
23867017-9	2013	Furthermore, the ER chaperone AtBiP2 protein alleviated Cd(2+)-induced ER stress and PCD in BY-2 cells based on the fact that heterologous expression of AtBiP2 in tobacco BY-2 cells reduced the expression of NtBLP4 and a PCD-related gene NtHsr203J under Cd(2+) stress conditions.	Cadmium ion	56-62	Heat shock protein 70 (Hsp 70) family protein	Arabidopsis thaliana	30-36
23867017-9	2013	Furthermore, the ER chaperone AtBiP2 protein alleviated Cd(2+)-induced ER stress and PCD in BY-2 cells based on the fact that heterologous expression of AtBiP2 in tobacco BY-2 cells reduced the expression of NtBLP4 and a PCD-related gene NtHsr203J under Cd(2+) stress conditions.	Cadmium ion	56-62	Heat shock protein 70 (Hsp 70) family protein	Arabidopsis thaliana	153-159
23867017-9	2013	Furthermore, the ER chaperone AtBiP2 protein alleviated Cd(2+)-induced ER stress and PCD in BY-2 cells based on the fact that heterologous expression of AtBiP2 in tobacco BY-2 cells reduced the expression of NtBLP4 and a PCD-related gene NtHsr203J under Cd(2+) stress conditions.	Cadmium ion	56-62	luminal-binding protein 4	Nicotiana tabacum	208-214
23867017-9	2013	Furthermore, the ER chaperone AtBiP2 protein alleviated Cd(2+)-induced ER stress and PCD in BY-2 cells based on the fact that heterologous expression of AtBiP2 in tobacco BY-2 cells reduced the expression of NtBLP4 and a PCD-related gene NtHsr203J under Cd(2+) stress conditions.	Cadmium ion	254-260	Heat shock protein 70 (Hsp 70) family protein	Arabidopsis thaliana	30-36
23867017-9	2013	Furthermore, the ER chaperone AtBiP2 protein alleviated Cd(2+)-induced ER stress and PCD in BY-2 cells based on the fact that heterologous expression of AtBiP2 in tobacco BY-2 cells reduced the expression of NtBLP4 and a PCD-related gene NtHsr203J under Cd(2+) stress conditions.	Cadmium ion	254-260	Heat shock protein 70 (Hsp 70) family protein	Arabidopsis thaliana	153-159
23867017-9	2013	Furthermore, the ER chaperone AtBiP2 protein alleviated Cd(2+)-induced ER stress and PCD in BY-2 cells based on the fact that heterologous expression of AtBiP2 in tobacco BY-2 cells reduced the expression of NtBLP4 and a PCD-related gene NtHsr203J under Cd(2+) stress conditions.	Cadmium ion	254-260	luminal-binding protein 4	Nicotiana tabacum	208-214
23867017-10	2013	In summary, these results suggest that the ER stress-cell death signaling pathway regulates Cd(2+)-induced PCD in tobacco BY-2 cells, and that the AtBiP2 protein act as a negative regulator in this process.	Cadmium ion	92-98	Heat shock protein 70 (Hsp 70) family protein	Arabidopsis thaliana	147-153
21930242-3	2012	Both zinc (Zn(2+)) and iron (Fe(2+)) inhibited cellular Cd(2+) uptake through a competitive interaction, suggesting that Cd(2+) enters enterocytes via both Zn(2+) (e.g., ZIP8) and Fe(2+) (e.g., DMT1) transport pathways.	Cadmium ion	121-127	solute carrier family 39 member 8	Homo sapiens	170-174
23225856-4	2012	The expression of some genes responsible for Cd(2+) transportation into vacuoles was induced, and the expression of the iron-regulated transporter 1 (IRT1) related to Cd(2+) absorption from the environment was not induced in wild type with Cd(2+) treatment.	Cadmium ion	167-173	iron-regulated transporter 1	Arabidopsis thaliana	120-148
23225856-4	2012	The expression of some genes responsible for Cd(2+) transportation into vacuoles was induced, and the expression of the iron-regulated transporter 1 (IRT1) related to Cd(2+) absorption from the environment was not induced in wild type with Cd(2+) treatment.	Cadmium ion	167-173	iron-regulated transporter 1	Arabidopsis thaliana	150-154
23225856-4	2012	The expression of some genes responsible for Cd(2+) transportation into vacuoles was induced, and the expression of the iron-regulated transporter 1 (IRT1) related to Cd(2+) absorption from the environment was not induced in wild type with Cd(2+) treatment.	Cadmium ion	167-173	iron-regulated transporter 1	Arabidopsis thaliana	120-148
23225856-4	2012	The expression of some genes responsible for Cd(2+) transportation into vacuoles was induced, and the expression of the iron-regulated transporter 1 (IRT1) related to Cd(2+) absorption from the environment was not induced in wild type with Cd(2+) treatment.	Cadmium ion	167-173	iron-regulated transporter 1	Arabidopsis thaliana	150-154
21930242-4	2012	Cellular Cd(2+) uptake increased in the presence of HCO(3)(-), which resembled the function of mammalian ZIP8.	Cadmium ion	9-15	solute carrier family 39 member 8	Homo sapiens	105-109
21479540-5	2011	The single treatment with the high concentration of Cd(2+) (>6 mg L(-1)) or acid rain at pH 2.5 decreased the activities of peroxidase and catalase, damaged the cell membrane and then decreased the seed germination of soybean.	Cadmium ion	52-58	peroxidase	Glycine max	127-137
21479540-5	2011	The single treatment with the high concentration of Cd(2+) (>6 mg L(-1)) or acid rain at pH 2.5 decreased the activities of peroxidase and catalase, damaged the cell membrane and then decreased the seed germination of soybean.	Cadmium ion	52-58	catalase-3	Glycine max	142-150
18533113-0	2008	Noncooperative cadmium(II) binding to human metallothionein 1a.	Cadmium ion	15-26	metallothionein 1A	Homo sapiens	44-62
20105457-8	2010	Cd(2+) induced an increased release of IL-6 and MIP-2/CXCL2 from the epithelial cells and MIP-2, IL-1beta and TNF-alpha from alveolar macrophages.	Cadmium ion	0-6	interleukin 6	Homo sapiens	39-43
20105457-8	2010	Cd(2+) induced an increased release of IL-6 and MIP-2/CXCL2 from the epithelial cells and MIP-2, IL-1beta and TNF-alpha from alveolar macrophages.	Cadmium ion	0-6	C-X-C motif chemokine ligand 2	Homo sapiens	48-53
20105457-8	2010	Cd(2+) induced an increased release of IL-6 and MIP-2/CXCL2 from the epithelial cells and MIP-2, IL-1beta and TNF-alpha from alveolar macrophages.	Cadmium ion	0-6	C-X-C motif chemokine ligand 2	Homo sapiens	54-59
20105457-8	2010	Cd(2+) induced an increased release of IL-6 and MIP-2/CXCL2 from the epithelial cells and MIP-2, IL-1beta and TNF-alpha from alveolar macrophages.	Cadmium ion	0-6	C-X-C motif chemokine ligand 2	Homo sapiens	90-95
20105457-8	2010	Cd(2+) induced an increased release of IL-6 and MIP-2/CXCL2 from the epithelial cells and MIP-2, IL-1beta and TNF-alpha from alveolar macrophages.	Cadmium ion	0-6	interleukin 1 beta	Homo sapiens	97-105
20105457-8	2010	Cd(2+) induced an increased release of IL-6 and MIP-2/CXCL2 from the epithelial cells and MIP-2, IL-1beta and TNF-alpha from alveolar macrophages.	Cadmium ion	0-6	tumor necrosis factor	Homo sapiens	110-119
19469490-2	2009	For all cadmium(II)-cysteine molar ratios, the mean Cd-S and Cd-(N/O) bond distances were found in the ranges 2.52-2.54 and 2.27-2.35 A, respectively.	Cadmium ion	8-19	CDP-diacylglycerol synthase 1	Homo sapiens	52-56
19469490-3	2009	The corresponding cadmium(II)-penicillamine complexes showed slightly shorter Cd-S bonds, 2.50-2.53 A, but with the Cd-(N/O) bond distances in a similar wide range, 2.28-2.33 A.	Cadmium ion	18-29	CDP-diacylglycerol synthase 1	Homo sapiens	78-82
18506790-5	2008	We previously showed that Cd(2+) increased phosphorylation of Erk and CaMK-II, and CaMK-II activation increased cell death in an Erk-independent manner.	Cadmium ion	26-32	mitogen-activated protein kinase 1	Mus musculus	62-65
18506790-5	2008	We previously showed that Cd(2+) increased phosphorylation of Erk and CaMK-II, and CaMK-II activation increased cell death in an Erk-independent manner.	Cadmium ion	26-32	calcium/calmodulin-dependent protein kinase II gamma	Mus musculus	70-77
18506790-6	2008	Here we demonstrate that Cd(2+) increases Jnk and p38 kinase phosphorylation, and inhibition of p38-but not of Jnk-increases cell viability by suppressing apoptosis in preference to apoptosis-like death.	Cadmium ion	25-31	mitogen-activated protein kinase 8	Mus musculus	42-45
18506790-6	2008	Here we demonstrate that Cd(2+) increases Jnk and p38 kinase phosphorylation, and inhibition of p38-but not of Jnk-increases cell viability by suppressing apoptosis in preference to apoptosis-like death.	Cadmium ion	25-31	mitogen-activated protein kinase 14	Mus musculus	50-53
18506790-14	2008	Activation of p38 kinase and of CaMK-II by Cd(2+) are associated with caspase-independent apoptosis that is not dependent on mitochondrial destabilization.	Cadmium ion	43-49	mitogen-activated protein kinase 14	Mus musculus	14-17
18506790-14	2008	Activation of p38 kinase and of CaMK-II by Cd(2+) are associated with caspase-independent apoptosis that is not dependent on mitochondrial destabilization.	Cadmium ion	43-49	calcium/calmodulin-dependent protein kinase II gamma	Mus musculus	32-39
18329799-10	2008	Cadmium(II) is adsorbed to the clay surfaces as a six-coordinated CdO(6) complex in octahedral fashion, but it is not possible to distinguish if cadmium is hydrated or partly hydrolysed.	Cadmium ion	0-11	cell adhesion associated, oncogene regulated	Homo sapiens	66-69
17355438-8	2007	Together, these data strongly support a role for AtPDR8 as an efflux pump of Cd(2+) or Cd conjugates at the plasma membrane of Arabidopsis cells.	Cadmium ion	77-83	ABC-2 and Plant PDR ABC-type transporter family protein	Arabidopsis thaliana	49-55
16852094-1	2005	In this paper, we present a state-of-the-art 100 ns molecular dynamics simulation of a cadmium(II) aqueous solution that highlights a very flexible ion first coordination shell which transits between hexa- and heptahydrated complexes.	Cadmium ion	87-98	hexosaminidase subunit alpha	Homo sapiens	200-204
16477124-9	2006	Reduced glutathione (GSH) is an important antioxidant and the precursor of PCs, glutamylcysteine synthetase (GCS) and glutathione synthetase (GS) catalyze GSH synthesis from Cys, overexpression of the two enzymes can improve Cd(2+) tolerance in plant.	Cadmium ion	225-231	glutathione synthetase	Homo sapiens	118-140
15236559-1	2004	A voltammetric study of the stability of the complexes of cadmium(II) with 12-crown-4,15-crown-5 and 18-crown-6 in aqueous solution and the structures of [Cd(benzo-18-crown-6)(NCS)(2)] and [K(18-crown-6)][Cd(SCN)(3)].	Cadmium ion	58-69	sorcin	Homo sapiens	208-211
9351472-0	1997	Recombinant synthesis of mouse Zn3-beta and Zn4-alpha metallothionein 1 domains and characterization of their cadmium(II) binding capacity.	Cadmium ion	110-121	metallothionein 1	Mus musculus	54-71
34492766-2	2021	Coordination self-assembly of the in situ formed aggregation-induced emission polytetrazole luminogen with cadmium(II) ion produces an unprecedented tetrazolyl-TPE-based microporous cationic metal-organic framework (MOF) with an unusual (4,5,8T14)-connected net of {(Cd4(H4ttpe)2Cl5) (N3)3}, in which the H4ttpe serves as the first undeprotonated tetrazole ligand of octa-coordinating bridging mode.	Cadmium ion	107-118	CD4 molecule	Homo sapiens	267-270
3349033-1	1988	The binding of cadmium(II) to human serum transferrin in 0.01 M N-(2-hydroxyethyl)-piperazine-N"-2-ethanesulfonic acid with 5 mM bicarbonate at 25 degrees C has been evaluated by difference ultraviolet spectroscopy.	Cadmium ion	15-26	transferrin	Homo sapiens	42-53
12099876-8	2002	The cadmium(II) complex is tetragonal, P4(2)/n (No.	Cadmium ion	4-15	erythrocyte membrane protein band 4.2	Homo sapiens	39-44
2298732-0	1990	Arsenite and cadmium(II) as probes of glucocorticoid receptor structure and function.	Cadmium ion	13-24	nuclear receptor subfamily 3, group C, member 1	Rattus norvegicus	38-61
35348554-1	2022	A novel CdII-based two-fold interpenetrated metal-organic framework (MOF), namely {(Cd2(BTDB)2(4,4-bpy)) DMF}n (JXUST-14), (H2BTDB = 4,4"-(benzo(c)(1,2,5)thiadiazole-4,7-diyl)dibenzoic acid and 4,4-bpy = 4,4-bipyridine), has been prepared and characterized.	Cadmium ion	8-12	CD2 molecule	Homo sapiens	84-87