PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
9146848-1	1997	AIMS: Triazolam, a triazolobenzodiazepine hypnotic agent, is metabolized by CYP3A4.	triazolobenzodiazepine	19-41	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	76-82
9608607-0	1998	Mechanism of triazolo-benzodiazepine and benzodiazepine action in anxiety and depression: behavioral studies with concomitant in vivo CA1 hippocampal norepinephrine and serotonin release detection in the behaving animal.	triazolobenzodiazepine	13-36	carbonic anhydrase 1	Rattus norvegicus	134-137
9608607-6	1998	Time course studies showed that the mechanism of action of the triazolobenzodiazepine (TBZD), adinazolam, (Deracyn) is dramatically different from that of the classical benzodiazepine (BZD), diazepam (Valium, i.e., adinazolam increased, whereas diazepam decreased, 5-HT release within CA1 region of hippocampus in the freely moving and behaving rat.	triazolobenzodiazepine	63-85	carbonic anhydrase 1	Rattus norvegicus	285-288
9185044-7	1997	Our results suggest that PAF antagonists with affinities for intracellular binding sites and/or specific structures derived from triazolobenzodiazepine could be of therapeutic use to limit the breakdown of the ECM and the development of ulcer formation.	triazolobenzodiazepine	129-151	PCNA clamp associated factor	Homo sapiens	25-28
26367539-0	2016	New Synthetic Routes to Triazolo-benzodiazepine Analogues: Expanding the Scope of the Bump-and-Hole Approach for Selective Bromo and Extra-Terminal (BET) Bromodomain Inhibition.	triazolobenzodiazepine	24-47	delta/notch like EGF repeat containing	Homo sapiens	149-152
26367539-1	2016	We describe new synthetic routes developed toward a range of substituted analogues of bromo and extra-terminal (BET) bromodomain inhibitors I-BET762/JQ1 based on the triazolo-benzodiazepine scaffold.	triazolobenzodiazepine	166-189	delta/notch like EGF repeat containing	Homo sapiens	112-115
12798263-8	2003	It suggests that triazolobenzodiazepine-induced retrograde amnesia may be mediated through blockade of PAF receptors.	triazolobenzodiazepine	17-39	patchy fur	Mus musculus	103-106
8347138-4	1993	The triazolobenzodiazepine effects on t-PA production were accompanied by parallel increases in t-PA mRNA levels, without marked changes in PAI-1 or glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA concentrations.	triazolobenzodiazepine	4-26	plasminogen activator, tissue type	Homo sapiens	38-42
7901754-2	1993	We found in this study that even the beta 2 gamma 2 subtype displays gamma-aminobutyric acid-induced Cl- currents that are potentiated by triazolam (a triazolobenzodiazepine).	triazolobenzodiazepine	151-173	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	37-43
8347138-4	1993	The triazolobenzodiazepine effects on t-PA production were accompanied by parallel increases in t-PA mRNA levels, without marked changes in PAI-1 or glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA concentrations.	triazolobenzodiazepine	4-26	plasminogen activator, tissue type	Homo sapiens	96-100
2893525-3	1987	We have found that the psychotropic triazolobenzodiazepine drugs, alprazolam and triazolam, potently (IC50 less than 1 microM) inhibit PAF-induced shape change, aggregation and secretion of human platelets.	triazolobenzodiazepine	36-58	PCNA clamp associated factor	Homo sapiens	135-138
1480515-2	1992	Here, we examined the effects of an antianxiety triazolobenzodiazepine, adinazolam, on corticotropin-releasing factor (CRF)-stimulated POMC peptide secretion from the rat neurointermediate pituitary.	triazolobenzodiazepine	48-70	corticotropin releasing hormone	Rattus norvegicus	87-117
1667341-2	1991	Triazolobenzodiazepine compounds are active both at the GABAA receptor and as PAF antagonists.	triazolobenzodiazepine	0-22	PCNA clamp associated factor	Homo sapiens	78-81
2845442-5	1988	Furthermore, the triazolobenzodiazepine, alprazolam, antagonized the narcoleptic effect of TRH.	triazolobenzodiazepine	17-39	thyrotropin releasing hormone	Homo sapiens	91-94
6150550-3	1984	It was found that in washed human platelets the psychotropic triazolobenzodiazepine drugs alprazolam and triazolam potently inhibited PAF-induced changes in shape, aggregation, and secretion.	triazolobenzodiazepine	61-83	PCNA clamp associated factor	Homo sapiens	134-137
6135430-0	1983	[Experimental study on the activity of the triazolo-benzodiazepine GP 55 129 compared with diazepam and placebo in healthy volunteers].	triazolobenzodiazepine	43-66	neuroplastin	Homo sapiens	67-72