PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 8723743-4 1996 Studies were conducted, using human liver microsomes, to characterize the CYP450 enzymes responsible for the in vitro metabolism of red-dolasetron. red-dolasetron 132-146 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 74-80 8723743-13 1996 Red-dolasetron was a competitive inhibitor of CYP2D6, with an IC50 value of 70 microM, which is 2 orders of magnitude above maximum plasma concentrations found in humans. red-dolasetron 0-14 cytochrome P450 family 2 subfamily D member 6 Homo sapiens 46-52