PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 19877632-5 2009 This discovery could open a new route to hydrocarbons via i-propanol from syn-gas or biobased feedstocks. 2-Propanol 58-68 synemin Homo sapiens 74-77 18425739-7 2008 Pure trimeric Hpca (triphenylisomelamine) was obtained either by recrystallization of the mixed crystals from boiling water or by trimerization of monomeric Hpca in isopropanol for 12 h under reflux conditions. 2-Propanol 165-176 hippocalcin Homo sapiens 14-18 19660780-1 2009 Photolysis of deca-bromodiphenyl ether (BDE-209) was investigated in tetrahydrofuran, dichloromethane, isopropanol, acetone, ethanol, methanol, acetonitrile and dimethylsulfoxide. 2-Propanol 103-114 homeobox D13 Homo sapiens 40-43 18926719-5 2009 Herein, one such application has been further demonstrated in the detection and identification of background ions from LC solvents and APPI dopants, including water, acetonitrile, chloroform, methylene chloride, methanol, 2-propanol, hexanes, heptane, cyclohexane, acetone, tetrahydrofuran (THF), 1,4-dioxane, toluene, and anisole. 2-Propanol 222-232 amyloid beta precursor protein Homo sapiens 135-139 18829045-4 2008 It is observed that BET constant value goes through a minimum, whereas the shapes of distribution function of the adsorption energies of isopropanol are changing. 2-Propanol 137-148 delta/notch like EGF repeat containing Homo sapiens 20-23 18684924-6 2008 Furthermore, we show in a model of acute IPA intoxication that animals became immunosuppressed as judged by their reduced ability to release IL-2 and IFN-gamma in the serum in response to staphylococcal enterotoxin B. 2-Propanol 41-44 interleukin 2 Homo sapiens 141-145 18684924-6 2008 Furthermore, we show in a model of acute IPA intoxication that animals became immunosuppressed as judged by their reduced ability to release IL-2 and IFN-gamma in the serum in response to staphylococcal enterotoxin B. 2-Propanol 41-44 interferon gamma Homo sapiens 150-159 19291738-3 2009 The crystal structures of bovine pancreatic ribonuclease A (RNAse A) soaked in the following organic solvents are presented: 50% dioxane, 50% dimethylformamide, 70% dimethylsulfoxide, 70% 1,6-hexanediol, 70% isopropanol, 50% R,S,R-bisfuran alcohol, 70% t-butanol, 50% trifluoroethanol, or 1.0M trimethylamine-N-oxide. 2-Propanol 208-219 ribonuclease pancreatic Bos taurus 44-58 18997320-2 2008 N-terminally truncated ALG-2 (des3-23ALG-2) was crystallized by the vapour-diffusion method in buffer consisting of either 50 mM MES pH 6.5, 12.5%(v/v) 2-propanol and 150 mM calcium acetate or 100 mM MES pH 6.0, 15%(v/v) ethanol and 200 mM zinc acetate. 2-Propanol 152-162 ALG2 alpha-1,3/1,6-mannosyltransferase Homo sapiens 23-28 18721997-0 2008 The pathway of dechlorination of PCB congener by a photochemical chain process in 2-propanol: the role of medium and quenching. 2-Propanol 82-92 pyruvate carboxylase Homo sapiens 33-36 18721997-1 2008 As part of a program aimed at developing a field process for cleanup of PCB contaminated soils using photochemistry in basic 2-propanol, additional details of the dechlorination pathway are presented. 2-Propanol 125-135 pyruvate carboxylase Homo sapiens 72-75 19049039-1 2008 A new sorbent material, polymer embedded nano crystalline titania (Titanium Polymer-TiP) has been developed, from titanium (IV) chloride and isopropyl alcohol, for the adsorption of 99Mo, which is a precursor to 99mTc, a workhorse in radio-pharmaceuticals. 2-Propanol 141-158 TOR signaling pathway regulator Homo sapiens 84-87 17994554-5 2008 Here, the secondary structure of gamma-zein has been analyzed by circular dichroism in SDS aqueous solution with and without ditiothreitol (DTT), and in 60% of 2-propanol and water with DTT. 2-Propanol 160-170 prolamin 50 kDa gamma zein Zea mays 33-43 17715970-1 2007 A nanosecond time-resolved resonance Raman (ns-TR3) spectroscopic study of the triplet state benzophenone reaction with the 2-propanol hydrogen-donor solvent and subsequent reactions is presented. 2-Propanol 124-134 nuclear receptor subfamily 4 group A member 1 Homo sapiens 47-50 17804228-2 2007 The structural features required for optimal binding to the 5-HT1A receptor are as follows: S-2-propanol linker, 4-indoloxy substituent, and a large lipophilic cyclic amine substituent. 2-Propanol 92-104 5-hydroxytryptamine receptor 1A Homo sapiens 60-75 18803204-8 2008 The complexes [MX(CN"N)(P2)] (1-15) (M=Ru, Os; X=Cl, H, OR; P=PPh3 and P2=diphosphane) are efficient catalysts for the TH of carbonyl compounds with 2-propanol in the presence of NaOiPr (2 mol %). 2-Propanol 149-159 protein phosphatase 4 catalytic subunit Homo sapiens 62-66 17715970-2 2007 The TR3 spectra show that the benzophenone triplet state (npi*) hydrogen-abstraction reaction with 2-propanol is very fast (about 10 to 20 ns) and forms a diphenylketyl radical and an associated 2-propanol radical partner. 2-Propanol 99-109 nuclear receptor subfamily 4 group A member 1 Homo sapiens 4-7 17629753-0 2007 Investigation of the intermolecular proton transfer in the supersystems adenine-methanol/ethanol/i-propanol: MP2 and DFT levels study. 2-Propanol 97-107 tryptase pseudogene 1 Homo sapiens 109-112 17516063-7 2007 N. crassa ADH1 preferred primary alcohols containing C3-C8 carbons to secondary alcohols such as 2-propanol and 2-butanol. 2-Propanol 97-107 alcohol dehydrogenase I Neurospora crassa OR74A 10-14 17637966-2 2007 A procedure for the synthesis of 6,19-cyclopregnanes is described involving an intramolecular alkylation reaction of Delta(4)-3-keto steroids with a 19-mesylate in the presence of KOH in isopropanol. 2-Propanol 187-198 delta like canonical Notch ligand 4 Rattus norvegicus 117-127 17241021-2 2007 Well-defined double hydrophilic miktoarm AB4 star copolymer, PNIPAM-b-(PDEA)4, was then synthesized by polymerizing 2-(diethylamino)ethyl methacrylate (DEA) via ATRP in 2-propanol at 45 degrees C using 1b, where PDEA was poly(2-(diethylamino)ethyl methacrylate). 2-Propanol 169-179 phosphodiesterase 6A Homo sapiens 71-75 17265537-4 2007 The value of log k linearly decreases with increasing phi for methanol, ethanol, or ACN, while decreases by a second-degree polynomial with increasing phi for 2-propanol. 2-Propanol 159-169 apoptotic chromatin condensation inducer 1 Homo sapiens 84-87 16395432-10 2006 The radical ion Cl2- could be successfully detected by photolysing in 2-propanol-water (1 : 1) in the presence of Cl-. 2-Propanol 70-80 endogenous retrovirus group W member 5 Homo sapiens 16-19 18045235-1 2007 Wild type of bovine thrombin has been crystallized in a ligand-free form by the hanging drop vapor diffusion method with polyethylene glycol 4000 and 2-propanol. 2-Propanol 150-160 coagulation factor II, thrombin Bos taurus 20-28 16506866-3 2006 The quantum yield of oxygen uptake (Phi(-O(2))) increases with increasing 2-propanol concentration up to 0.9. 2-Propanol 74-84 glucose-6-phosphate isomerase Homo sapiens 36-39 17177511-3 2006 The 100% methanol, 75% ethanol, and 40% 2-propanol extracts of black cohosh effectively displaced the specific binding of [3H]DAMGO to hMOR. 2-Propanol 40-50 opioid receptor mu 1 Homo sapiens 135-139 17077902-5 2006 Phi(-O2) = 0.3-0.6 in the presence of 1 M 2-propanol and 3-10 mM ascorbic acid or EDTA. 2-Propanol 42-52 glucose-6-phosphate isomerase Homo sapiens 0-3 16715514-4 2006 Pure alcohols such ethanol or 2-propanol, with a fixed percentage of DEA added, serve as valuable alternatives to the more common n-hexane-based normal-phase eluents in resolution of Mianserin on the AD CSP. 2-Propanol 30-40 DnaJ heat shock protein family (Hsp40) member C5 Homo sapiens 203-206 15910339-3 2005 Enzyme activity measurements of the ADH-2 amino acid polymorphism in D. mojavensis suggest that the Fast allozyme allele has a higher activity on 2-propanol than 1-propanol. 2-Propanol 146-156 alcohol dehydrogenase 2 Drosophila mojavensis 36-41 16076117-11 2005 Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of 60% 2-propanol-extracted proteins showed a drastic reduction in the accumulation of BBI with increasing protein content. 2-Propanol 65-75 LOC547785 Glycine max 145-148 15927620-2 2005 The resulting CdS nanoparticles-aluminosilicate composites (ASCdS) were used as photocatalysts for H2 generation from 2-propanol aqueous solution. 2-Propanol 118-128 CDP-diacylglycerol synthase 1 Homo sapiens 14-17 15726639-6 2005 2-propanol exposure inhibited ADH-2 specific activity in both genotypes from all localities, but inhibition was significantly less in two populations of race BII flies homozygous for Adh-2F. 2-Propanol 0-10 alcohol dehydrogenase 2 Drosophila mojavensis 30-35 15726639-8 2005 ADH-1 activity in female ovaries was inhibited less by 2-propanol than ADH-2. 2-Propanol 55-65 alcohol dehydrogenase 1 Drosophila mojavensis 0-5 15702183-7 2005 In the presence of isopropanol, complexes 1-3 initiated the living ring-opening polymerization of rac-lactide (PDI = 1.03-1.06, Mw/Mn). 2-Propanol 19-30 peptidyl arginine deiminase 1 Homo sapiens 111-118 15560792-8 2004 In addition, 2-propanol derived from the crystallization solution occupied the hydrophobic cavity, which is proposed to be a CO trapping site in rat HO-1 that suppresses product inhibition. 2-Propanol 13-23 heme oxygenase 1 Rattus norvegicus 149-153 15581071-7 2004 The permeation study of a series of TMS and non-TMS systems showed that S-Ibu penetrated through shed snake skin faster than RS-Ibu, and the contents of IPA and menthol significantly affected the permeation rates of ibuprofen across shed snake skin, which may be attributed to the higher lipophilicity, and thus, higher solubility of S-Ibu in the skin than RS-Ibu. 2-Propanol 153-156 PYD and CARD domain containing Homo sapiens 36-39 15495733-4 2004 Furthermore, we proposed the placement of waterless, isopropyl alcohol-based, hand-cleaning systems in strategic locations throughout the ship, to help prevent and minimize the spread of future disease. 2-Propanol 53-70 inositol polyphosphate-5-phosphatase D Homo sapiens 138-142 15625320-3 2004 In unfolding experiments using methanol, ethanol, 2-propanol, trifluoroethanol (TFE), and sodium dodecyl sulfate (SDS), Tk-MGMT retained its native structure at high concentrations, despite the fact that these chemical solutions affect protein conformations in a number of different ways. 2-Propanol 50-60 O-6-methylguanine-DNA methyltransferase Homo sapiens 123-127 15478332-5 2004 Based on CLSM images of the GOx immobilized on the surfaces, it was concluded that the pre-cleaning process of gold substrates using different solvents, such as acetone, ethanol and 2-propanol, is very important for enhancing the GOx loading density. 2-Propanol 182-192 hydroxyacid oxidase 1 Homo sapiens 28-31 15478332-5 2004 Based on CLSM images of the GOx immobilized on the surfaces, it was concluded that the pre-cleaning process of gold substrates using different solvents, such as acetone, ethanol and 2-propanol, is very important for enhancing the GOx loading density. 2-Propanol 182-192 hydroxyacid oxidase 1 Homo sapiens 230-233 14570761-2 2003 Hepatocytes in culture showed rapid loss of CYP2E1 enzyme during 72 h. CYP2E1 inducers (ethanol, dimethyl sulfoxide, acetone, isopropanol, pyrazole, and imidazole) were able to prevent the fast decrease of the activities and protein levels of CYP2E1 enzyme. 2-Propanol 126-137 cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus 71-77 15244451-6 2004 Zein adsorption from 75% aqueous 2-propanol solutions, 0.05% to 0.5% w/v, onto hydrophilic and hydrophobic self-assembled monolayers (SAMs) formed by 11-mercaptoundecanoic acid and 1-octanethiol, respectively, was monitored by high time resolution SPR. 2-Propanol 33-43 zein Zea mays 0-4 14570761-2 2003 Hepatocytes in culture showed rapid loss of CYP2E1 enzyme during 72 h. CYP2E1 inducers (ethanol, dimethyl sulfoxide, acetone, isopropanol, pyrazole, and imidazole) were able to prevent the fast decrease of the activities and protein levels of CYP2E1 enzyme. 2-Propanol 126-137 cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus 71-77 14521400-0 2003 3,6-dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome c release via Bax channel modulation. 2-Propanol 47-57 cytochrome c, somatic Homo sapiens 81-93 14562314-6 2003 The ketone TRHY precatalyst [Ru(Cl)(2)((S,S)-cyP(2)(NH)(2))] ((S,S)-2), established at s:c=200, has also turned out to be a ketone HY precatalyst at up to s:c=10(6), again as tested on 3 in iPrOH under standard conditions. 2-Propanol 190-195 trichohyalin Homo sapiens 11-15 14562314-13 2003 The established achiral ketone TRHY precatalyst [Ru(Cl)(2)(ethP(2)(NH)(2))] (12) has turned out to be also a powerful precatalyst for the HY of 3 in iPrOH at s:c=10(6) and of some other substrates. 2-Propanol 149-154 trichohyalin Homo sapiens 31-35 14521400-2 2003 Here 3,6-dibromocarbazole piperazine derivatives of 2-propanol are described as the first small and potent modulators of the cytochrome c release triggered by Bid-induced Bax activation in a mitochondrial assay. 2-Propanol 52-62 cytochrome c, somatic Homo sapiens 125-137 14521400-0 2003 3,6-dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome c release via Bax channel modulation. 2-Propanol 47-57 BCL2 associated X, apoptosis regulator Homo sapiens 106-109 14521400-2 2003 Here 3,6-dibromocarbazole piperazine derivatives of 2-propanol are described as the first small and potent modulators of the cytochrome c release triggered by Bid-induced Bax activation in a mitochondrial assay. 2-Propanol 52-62 BH3 interacting domain death agonist Homo sapiens 159-162 14521400-2 2003 Here 3,6-dibromocarbazole piperazine derivatives of 2-propanol are described as the first small and potent modulators of the cytochrome c release triggered by Bid-induced Bax activation in a mitochondrial assay. 2-Propanol 52-62 BCL2 associated X, apoptosis regulator Homo sapiens 171-174 12952416-6 2003 A 40% 2-propanol extract of black cohosh was tested against 10 subtypes of the serotonin receptor, revealing the presence of compounds with strong binding to the 5-HT(1A), 5-HT(1D), and 5-HT(7) subtypes. 2-Propanol 6-16 5-hydroxytryptamine receptor 1A Rattus norvegicus 162-169 12952416-6 2003 A 40% 2-propanol extract of black cohosh was tested against 10 subtypes of the serotonin receptor, revealing the presence of compounds with strong binding to the 5-HT(1A), 5-HT(1D), and 5-HT(7) subtypes. 2-Propanol 6-16 5-hydroxytryptamine receptor 1D Rattus norvegicus 172-179 12952416-8 2003 The black cohosh 40% 2-propanol extract inhibited [(3)H]lysergic acid diethylamide (LSD) binding to the human 5-HT(7) receptor (IC(50) = 2.4 +/- 0.4 microg/mL) with greater potency than binding of [(3)H]-8-hydroxy-2-(di-N-propylamino)tetralin to the rat 5-HT(1A) receptor (IC(50) = 13.9 +/- 0.6 microg/mL). 2-Propanol 21-31 5-hydroxytryptamine receptor 1A Rattus norvegicus 254-261 14571976-1 2003 Soybean peroxidase (20 mg) catalyzed the oxidative polymerization of cardanol in 2-propanol/phospate buffer solution (25 ml, 1:1 v/v) and yielded 62% polycardanol over 6 h. Cobalt naphthenate (0.5% w/w) catalyzed the crosslinking of polycardanol and the final hardness of crosslinked polycardanol film exceeded 9 H scale as pencil scratch hardness, which shows a high potential as a commercial coating material. 2-Propanol 81-91 peroxidase Glycine max 8-18 12842038-1 2003 Room temperature crystal structures of crosslinked H-Ras bound to GMPPNP were solved in 50% 2,2,2-trifluoroethanol, 60% 1,6-hexanediol, and 50% isopropanol. 2-Propanol 144-155 HRas proto-oncogene, GTPase Homo sapiens 51-56 12777821-2 2003 Recombinant yeast cytosine deaminase has been crystallized with the inhibitor 2-hydroxypyrimidine in 10% 2-propanol, 20% polyethylene glycol 4000, 0.1 M HEPES pH 7.5. 2-Propanol 105-115 cytosine deaminase Saccharomyces cerevisiae S288C 18-36 11231926-7 2001 Ethanol, methanol, isopropanol, tert-butanol, and red wine all potentiated oxysterol-induced cell death up to 5-fold, paralleled by further induction of caspase-3. 2-Propanol 19-30 caspase 3 Homo sapiens 153-162 11856838-1 2002 Crystals of the Oct-1 POU/SNAP190 peptide/DNA tertiary complex have been obtained by hanging-drop vapor diffusion at 293K in 20% 2-propanol, 20% PEG 4000 and 0.1M sodium citrate pH 5.6. 2-Propanol 129-139 POU class 2 homeobox 1 Homo sapiens 16-21 11856838-1 2002 Crystals of the Oct-1 POU/SNAP190 peptide/DNA tertiary complex have been obtained by hanging-drop vapor diffusion at 293K in 20% 2-propanol, 20% PEG 4000 and 0.1M sodium citrate pH 5.6. 2-Propanol 129-139 small nuclear RNA activating complex polypeptide 4 Homo sapiens 26-33 12545511-5 2001 The ballpoint pen ink spots were eluted in a solvent of isopropyl alcohol. 2-Propanol 56-73 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 14-17 16290766-2 2002 The resulting CdS-Zn-SiO(2) composite was then used as a photocatalyst for the generation of H(2) from 2-propanol aqueous solution. 2-Propanol 103-113 CDP-diacylglycerol synthase 1 Homo sapiens 14-17 11850338-4 2002 Solid phase binding of the hydrophobic SP-C was achieved by transfer of the standard or BALF samples (diluted in 80% isopropanol, pH 3.5) to polystyrene microtiter plates. 2-Propanol 117-128 surfactant protein C Homo sapiens 39-43 11188697-6 2000 The enhanced resolution enabled a more accurate modeling of less-well-ordered regions and provided conclusive identification of the density in the central cavity at the crux of the gp120-CD4 interaction as isopropanol from the crystallization medium. 2-Propanol 206-217 Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1 181-186 11150504-3 2000 Using the precipitation reagents phosphotungstate or isopropanol, MPO co-precipitated with LDL, retaining its catalytic activity. 2-Propanol 53-64 myeloperoxidase Homo sapiens 66-69 11351543-10 2001 2-Propanol as an electron donor was efficient in the present RuIIL3/TiO2/CCl4 system, which showed no sign of deceleration in the dechlorination rate up to 6 h of irradiation. 2-Propanol 0-10 C-C motif chemokine ligand 4 Homo sapiens 73-77 11188697-6 2000 The enhanced resolution enabled a more accurate modeling of less-well-ordered regions and provided conclusive identification of the density in the central cavity at the crux of the gp120-CD4 interaction as isopropanol from the crystallization medium. 2-Propanol 206-217 CD4 molecule Homo sapiens 187-190 10992240-4 2000 In addition, the rates of asymmetric sulfoxidation of thioanisole in isopropyl alcohol and in methanol catalyzed by horseradish peroxidase (HRP) were determined to be tens to hundreds of times faster than in water under otherwise identical conditions. 2-Propanol 69-86 peroxidase Glycine max 128-138 10992240-6 2000 Sulfoxidation of thioanisole catalyzed by four other hemoproteins (soybean peroxidase, myoglobin, hemoglobin, and cytochrome c) is also much faster in isopropyl alcohol than in water. 2-Propanol 151-168 peroxidase Glycine max 75-85 11049752-1 2000 A recombinant hexahistidine-tagged 18.5-kDa isoform of murine myelin basic protein has been characterized biochemically and immunogenically, by mass spectrometry, by circular dichroism under various conditions (in aqueous solution, with monosialoganglioside G(M1), and in 89% 2-propanol), and by transmission electron microscopy. 2-Propanol 276-286 myelin basic protein Mus musculus 62-82 11073261-2 2000 The charge state distributions of cytochrome c and myoglobin, formed from 47%/50%/3% water/solvent/acetic acid solutions, shift to lower charge (higher m/z) when the 50% solvent fraction is changed from water to methanol, to acetonitrile, to isopropanol. 2-Propanol 242-253 cytochrome c, somatic Homo sapiens 34-46 11073261-2 2000 The charge state distributions of cytochrome c and myoglobin, formed from 47%/50%/3% water/solvent/acetic acid solutions, shift to lower charge (higher m/z) when the 50% solvent fraction is changed from water to methanol, to acetonitrile, to isopropanol. 2-Propanol 242-253 myoglobin Homo sapiens 51-60 10571272-6 1999 RESULTS: NB1-cis-9-hexadecenyl insulin was synthesized by a one-step reductive alkylation in sodium salicylate and isopropanol solution in high yield (80%). 2-Propanol 115-126 insulin Bos taurus 31-38 10884300-3 2000 In this study, we present the measurement of apoB concentration in lipoproteins purified by ultracentrifugation by combining isopropanol precipitation and gas chromatography/mass spectrometry. 2-Propanol 125-136 apolipoprotein B Homo sapiens 45-49 10884300-5 2000 Apolipoprotein B-100 was selectively precipitated by isopropanol. 2-Propanol 53-64 apolipoprotein B Homo sapiens 0-20 10884300-9 2000 The isopropanol precipitate was verified as pure apoB (>97%) in lipoprotein fractions isolated from normo- and hyperlipidemic plasma and the method appeared reproducible. 2-Propanol 4-15 apolipoprotein B Homo sapiens 49-53 10631666-8 2000 It was found that the thiolamine-derived degradation products DIPT, DESH, and (DES)2 were removed with isopropyl alcohol extraction. 2-Propanol 103-120 delta 4-desaturase, sphingolipid 2 Homo sapiens 79-84 10350620-8 1999 Conversely, small angle X-ray scattering and gel permeation chromatography data on GdA in 2-propanol have revealed a massive aggregation of the protein. 2-Propanol 90-100 progestagen associated endometrial protein Homo sapiens 83-86 10544801-5 1999 The rate of inhibition of phenoloxidase by diethyldithiocarbamate and phenylthiocarbamate depended on the concentration of 2-propanol. 2-Propanol 123-133 Phox Drosophila melanogaster 26-39 10544801-0 1999 Properties of phenoloxidases generated from prophenoloxidase with 2-propanol and the natural activator in Drosophila melanogaster. 2-Propanol 66-76 Prophenoloxidase 1 Drosophila melanogaster 44-60 9920461-8 1998 Anti-rat CYP2B1 and CYP2E1 antibodies effectively inhibited DeiPr-ATZ, DeEt-ATZ and iPrOH-ATZ formations in both sexes. 2-Propanol 84-89 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 9-15 10089307-8 1999 One 2-propanol molecule trapped in the trimeric channel could be a lead compound for the design of TNF inhibitors. 2-Propanol 4-14 tumor necrosis factor Homo sapiens 99-102 9920461-8 1998 Anti-rat CYP2B1 and CYP2E1 antibodies effectively inhibited DeiPr-ATZ, DeEt-ATZ and iPrOH-ATZ formations in both sexes. 2-Propanol 84-89 cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus 20-26 9723163-0 1998 Reversible activation of prophenoloxidase with 2-propanol in Drosophila melanogaster. 2-Propanol 47-57 Prophenoloxidase 1 Drosophila melanogaster 25-41 9723163-1 1998 In Drosophila melanogaster, activation of prophenoloxidase with 2-propanol was analyzed. 2-Propanol 64-74 Prophenoloxidase 1 Drosophila melanogaster 42-58 9723163-3 1998 Activation of prophenoloxidase with 2-propanol is considered to be a reversible conformational change of the prophenoloxidase protein. 2-Propanol 36-46 Prophenoloxidase 1 Drosophila melanogaster 14-30 9723163-3 1998 Activation of prophenoloxidase with 2-propanol is considered to be a reversible conformational change of the prophenoloxidase protein. 2-Propanol 36-46 Prophenoloxidase 1 Drosophila melanogaster 109-125 9576330-3 1998 The structural abnormality was demonstrated by protein chemistry methods, involving, in addition to the classical techniques, a selective precipitation of the abnormal hemoglobin by isopropanol and a mass spectrometry analysis of the alphaT-9 peptide following carboxypeptidase digestion. 2-Propanol 182-193 hemoglobin subunit gamma 2 Homo sapiens 159-178 9673409-7 1998 TNF, LPS, hyperthermia or potassium thiocyanate slightly accelerated the production of large DNA fragments, as well as the induction of trace amounts of internucleosomal DNA cleavage in PMNs, which became detectable only after concentration by fractional isopropanol precipitation. 2-Propanol 255-266 tumor necrosis factor Homo sapiens 0-3 9688066-9 1998 Catalase, thiourea, bicinchoninic acid, and ethylenediaminetetraacetate were effective at stabilizing both peptides toward oxidation, while superoxide dismutase, mannitol, isopropanol, and sodium formate were ineffective. 2-Propanol 172-183 catalase Homo sapiens 0-8 9518463-9 1998 The MTCP-1 recombinant proteins display greater solubility, do not form disulfide linked dimers or oligomers, and elute at a lower isopropanol concentration than the corresponding TCL-1 proteins. 2-Propanol 131-142 mature T cell proliferation 1 Homo sapiens 4-10 9210788-4 1997 Pretreatment of flies with increasing concentrations of 2-propanol to inhibit alcohol dehydrogenase (ADH) activity resulted not only in a decreasing choice of acetic acid patches, but also in the laying of a decreasing number of eggs. 2-Propanol 56-66 Alcohol dehydrogenase Drosophila melanogaster 78-99 9339891-4 1997 The ADH activity and CRMs of the Adh(F) strain were 2.1 times higher than those of Adhs strain, and ADH activity was higher with isopropanol (secondary alcohol) than with ethanol (primary alcohol) as a substrate in both Adh(F) and Adh(S) strains. 2-Propanol 129-140 Alcohol dehydrogenase Drosophila melanogaster 33-36 9339891-4 1997 The ADH activity and CRMs of the Adh(F) strain were 2.1 times higher than those of Adhs strain, and ADH activity was higher with isopropanol (secondary alcohol) than with ethanol (primary alcohol) as a substrate in both Adh(F) and Adh(S) strains. 2-Propanol 129-140 Alcohol dehydrogenase Drosophila melanogaster 100-103 9339891-4 1997 The ADH activity and CRMs of the Adh(F) strain were 2.1 times higher than those of Adhs strain, and ADH activity was higher with isopropanol (secondary alcohol) than with ethanol (primary alcohol) as a substrate in both Adh(F) and Adh(S) strains. 2-Propanol 129-140 Alcohol dehydrogenase Drosophila melanogaster 220-234 27392398-4 1998 (R)- and (S)-ACS HCl thus obtained were recrystallized from a mixture of hydrochloric acid and 2-propanol, taking account of the solubility of (RS)-ACS HCl, efficiently yielding both enantiomers in optically pure forms. 2-Propanol 95-105 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Homo sapiens 13-16 9214296-1 1997 Large enhancements (maximum of 82-fold in terms of enzyme efficiency, Vmax/Km) of bacterial PI-PLC cyclic phosphodiesterase activity were observed in the presence of organic solvents miscible in water (dimethyl sulfoxide, dimethylformamide, and 2-propanol). 2-Propanol 245-255 phospholipase C beta 1 Homo sapiens 92-98 9210788-4 1997 Pretreatment of flies with increasing concentrations of 2-propanol to inhibit alcohol dehydrogenase (ADH) activity resulted not only in a decreasing choice of acetic acid patches, but also in the laying of a decreasing number of eggs. 2-Propanol 56-66 Alcohol dehydrogenase Drosophila melanogaster 101-104 9210788-5 1997 Adh-null mutant flies showed a similar change in behavior pattern after 2-propanol treatment. 2-Propanol 72-82 Alcohol dehydrogenase Drosophila melanogaster 0-3 8805511-3 1996 RESULTS: The crystal structure of the ternary complex of MLCR (with NADPH and 2-propanol) has been determined at 1.8 A resolution. 2-Propanol 78-88 carbonyl reductase 2 Mus musculus 57-61 9118891-8 1996 In contrast, pretreatment of rats with the CYP2E1-inducer isopropanol strongly enhanced benzene metabolism and the formation of phenolic metabolites. 2-Propanol 58-69 cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus 43-49 8887439-12 1996 These findings support the hypothesis that in response to increased infliction of CCl4 injury by isopropanol, augmented stimulation of cell division and tissue repair restrain the progression of injury and restore hepatic structure and function, thereby allowing the rats to survive. 2-Propanol 97-108 C-C motif chemokine ligand 4 Rattus norvegicus 82-86 8887439-13 1996 Further, antimitotic intervention with colchicine (1 mg/kg, ip) led to decreased S-phase synthesis, followed by 60% lethality in the isopropanol-pretreated group in contrast to 40% lethality in the group receiving CCl4 alone (H2O + CCl4). 2-Propanol 133-144 C-C motif chemokine ligand 4 Rattus norvegicus 232-236 9490511-4 1997 According to features of the inotropic action the studied agents were divided into two groups: Cth values of the former group were dependent on stimulation frequency (V, methanol, ethanol, isopropanol, chloral hydrate and acetone); Cth values of agents of the latter group were independent on stimulation frequency (n-butanol, n-pentanol, n-hexanol, and chloroform). 2-Propanol 189-200 V-set and immunoglobulin domain containing 2 Homo sapiens 95-98 28568248-3 1994 Propan-2-ol is converted into acetone by ADH in vitro. 2-Propanol 0-11 alcohol dehydrogenase Drosophila simulans 41-44 8055187-3 1994 Isopropanol treatment of microsomes extracted cytochrome b5 free of spectrophotometrically interfering cytochrome P-450. 2-Propanol 0-11 cytochrome b5 Musca domestica 46-59 8055187-4 1994 Studies using immunoblotting and rocket immunoelectrophoresis with polyclonal antisera raised against the purified cytochrome b5 showed that isopropanol treatment quantitatively extracted cytochrome b5. 2-Propanol 141-152 cytochrome b5 Musca domestica 115-128 8055187-4 1994 Studies using immunoblotting and rocket immunoelectrophoresis with polyclonal antisera raised against the purified cytochrome b5 showed that isopropanol treatment quantitatively extracted cytochrome b5. 2-Propanol 141-152 cytochrome b5 Musca domestica 188-201 8528653-3 1995 The large estimated partition coefficient of 1,2,3,4-TCDD in 10% 2-propanol/water (> 1000) indicates that on the C18 stationary phase, both the saturated hydrocarbon chains and the absorbed 2-propanol may act as proton donors and accelerate the photolysis. 2-Propanol 65-75 Bardet-Biedl syndrome 9 Homo sapiens 116-119 8528653-3 1995 The large estimated partition coefficient of 1,2,3,4-TCDD in 10% 2-propanol/water (> 1000) indicates that on the C18 stationary phase, both the saturated hydrocarbon chains and the absorbed 2-propanol may act as proton donors and accelerate the photolysis. 2-Propanol 193-203 Bardet-Biedl syndrome 9 Homo sapiens 116-119 7710944-3 1995 Cytotoxicity was prevented by the cytochrome P450 2E1 inhibitors phenyl imidazole, isoniazid, isopropanol or ethanol, suggesting that cytochrome P450 2E1 catalysed tirapazamine reductive bioactivation. 2-Propanol 94-105 cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus 34-53 7710944-3 1995 Cytotoxicity was prevented by the cytochrome P450 2E1 inhibitors phenyl imidazole, isoniazid, isopropanol or ethanol, suggesting that cytochrome P450 2E1 catalysed tirapazamine reductive bioactivation. 2-Propanol 94-105 cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus 134-153 7527401-6 1994 Furthermore, Kit receptors can be down-regulated by proteolytic cleavage induced by either activation of protein kinase C or by isopropyl alcohol. 2-Propanol 128-145 KIT proto-oncogene receptor tyrosine kinase Mus musculus 13-16 22191761-0 1994 .gamma.-Ray Destruction of Individual PCB Congeners in Neutral 2-propanol. 2-Propanol 63-73 pyruvate carboxylase Homo sapiens 38-41 28568255-3 1994 Alcohol dehydrogenase activity was assayed with both ethanol (E) and isopropanol (I). 2-Propanol 69-80 Alcohol dehydrogenase Drosophila melanogaster 0-21 1433198-1 1992 The 15-residue apolar peptide, Boc-Val-Ala-Leu-Aib-Val-Ala-Leu-(Val-Ala-Leu-Aib)2-OMe has been crystallized from 2-propanol-water (form I). 2-Propanol 113-123 ANIB1 Homo sapiens 47-50 8146271-6 1994 Radicals derived from isopropyl alcohol and glycerol also caused SSB formation in DNA, while those from 2-deoxyribose, thymine, 1,3-dimethylthymine and 1,3-dimethyluracil did not. 2-Propanol 22-39 small RNA binding exonuclease protection factor La Homo sapiens 65-68 8508190-0 1993 Activation of prophenoloxidase with 2-propanol and other organic compounds in Drosophila melanogaster. 2-Propanol 36-46 Prophenoloxidase 1 Drosophila melanogaster 14-30 8508190-1 1993 Activation with 2-propanol and other organic compounds of prophenoloxidase purified from pupae of Drosophila melanogaster was analyzed. 2-Propanol 16-26 Prophenoloxidase 1 Drosophila melanogaster 58-74 8508190-9 1993 The results suggested that the activation of A1 with 2-propanol is caused by the reversible conformational change of the prophenoloxidase molecule. 2-Propanol 53-63 Prophenoloxidase 1 Drosophila melanogaster 121-137 8343578-1 1993 The structure of the peptide Boc-Val-Ala-Leu-Aib-Val-Ala-Leu-OMe has been determined in crystals obtained from a dimethylsulfoxide-isopropanol mixture. 2-Propanol 131-142 ANIB1 Homo sapiens 45-48 1433198-1 1992 The 15-residue apolar peptide, Boc-Val-Ala-Leu-Aib-Val-Ala-Leu-(Val-Ala-Leu-Aib)2-OMe has been crystallized from 2-propanol-water (form I). 2-Propanol 113-123 ANIB1 Homo sapiens 76-79 1417753-6 1992 About 40% of the label from 125I-TC-CM was insoluble in 50% propan-2-ol, indicating association with CM apolipoprotein B48. 2-Propanol 60-71 apolipoprotein B Rattus norvegicus 104-122 1427042-3 1992 The variant beta-globin, (beta s2) of the Hbbs2 haplotype, also had an elevated oxygen affinity and in addition was moderately unstable in 19% isopropanol. 2-Propanol 143-154 hemoglobin beta chain complex Mus musculus 12-23 1954029-1 1991 Protamines 1 and 2 have been isolated from the sperm of frozen and isopropanol preserved Syrian hamster (Mesocricetus auratus) epididymides and analyzed by gel electrophoresis, high-performance liquid chromatography (HPLC), and amino acid analysis and sequencing. 2-Propanol 67-78 Prm1 Mesocricetus auratus 0-18 1367895-4 1992 The addition of 10-15% isopropyl alcohol to the aqueous phase increases the rate of protein release dramatically and allows for nearly complete back-transfer of porcine pepsin and 70% back-transfer of bovine chymosin. 2-Propanol 23-40 chymosin Bos taurus 208-216 1601952-2 1992 A new high-performance liquid chromatographic analysis for the study of HSA heterogeneity is described based on a high content of formic acid in the mobile phase combined with a concave gradient of isopropanol. 2-Propanol 198-209 albumin Homo sapiens 72-75 34517622-5 2021 The resolution ability of the beta-CD-COF@SiO2-packed column toward various chiral compounds was investigated using n-hexane/isopropanol as the mobile phase. 2-Propanol 125-136 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 30-37 2079871-4 1990 ApoB was isolated and quantified using precipitation with isopropanol. 2-Propanol 58-69 apolipoprotein B Rattus norvegicus 0-4 2124198-2 1990 In all experiments the ADH of flies revealed greater affinity to isopropanol than ethanol. 2-Propanol 65-76 Alcohol dehydrogenase Drosophila melanogaster 23-26 1691766-2 1990 Brief exposure of cells to methanol, ethanol, 2-propanol, or butanol resulted in the production of an acid-labile IFN which could be detected in the supernatant medium as early as 60 min after removal of the drug. 2-Propanol 46-56 interferon Gallus gallus 114-117 2119547-4 1990 The phospho-oligosaccharide-dependent incorporation of phosphate into ATP citrate lyase in intact cells is resistant to isopropanol and acetic acid, but the phosphoenzyme phosphorylated in cell extracts is acid labile. 2-Propanol 120-131 ATP citrate lyase Homo sapiens 70-87 1655380-8 1991 The following rate constants at 298 K have been measured (liter mol-1 sec-1): kOH (isopropanol) = 2.7 x 10(9) (relative to kOH (methanol) = 8.46 x 10(9]; kOH (toluene) = 6.0 x 10(9); and kOH (p-xylene) = 4.5 x 10(9) (relative to kOH (benzene) = 7.8 x 10(9]. 2-Propanol 83-94 secretory blood group 1, pseudogene Homo sapiens 70-75 2043649-3 1991 Long-lifetime tyrosinate fluorescence (LTF) of angiotensin II (ANG II) was observed in propylene glycol, trifluoroethanol and isopropanol but not in DMSO or water. 2-Propanol 126-137 angiotensinogen Rattus norvegicus 47-61 2043649-3 1991 Long-lifetime tyrosinate fluorescence (LTF) of angiotensin II (ANG II) was observed in propylene glycol, trifluoroethanol and isopropanol but not in DMSO or water. 2-Propanol 126-137 angiotensinogen Rattus norvegicus 63-69 2043649-5 1991 LTF for ANG II was longer in propylene glycol (21 ns) than in isopropanol (16 ns) whereas the % conformer(s) producing LTF was higher in isopropanol (79%) than in propylene glycol (19%). 2-Propanol 62-73 angiotensinogen Rattus norvegicus 8-14 32794734-5 2020 Adding nitrate to a solution of the [Cm(nPr-BTP)3]3+ complex in 2-propanol shifts the Cm(III) emission band from 613.1 to 617.3 nm. 2-Propanol 64-74 neuronal pentraxin receptor Homo sapiens 40-43 32797824-2 2020 50 mM NH4Ac (pH=9) with 20 % v/v isopropylalcohol was found optimal for efficient separation of insulin from its even 10 deamidated forms. 2-Propanol 33-49 insulin Homo sapiens 96-103 34087019-10 2021 Among them, dimethylamine and isopropanol were strongly associated with methane and propanoate metabolism respectively in AD with FLG mutations (FDR-adjusted P < 0.01). 2-Propanol 30-41 filaggrin Homo sapiens 130-133 34647730-3 2021 (UO2(OTf)2) reduces a series of aromatic and aliphatic aldehydes and ketones into their corresponding alcohols with moderate to excellent yields, using iPrOH as a solvent and a reductant. 2-Propanol 152-157 POU class 2 homeobox 2 Homo sapiens 1-10 34087019-11 2021 CONCLUSION: A strong correlation of microbial-derived metabolites, dimethylamine and isopropanol, with FLG mutations and IgE allergic reactions provides the influence of host genetics on the microbiome to regulate susceptibility to allergic responses in the pathogenesis of AD. 2-Propanol 85-96 filaggrin Homo sapiens 103-106 2673040-8 1989 Further, comparisons of the kinetic parameters of the bacterially produced enzyme and ADH activity in larval fly extracts indicate similar substrate preferences, pH dependencies, and Km values for 2-propanol and NAD. 2-Propanol 197-207 Alcohol dehydrogenase Drosophila melanogaster 86-89 34404870-6 2021 Using nuclear magnetic resonance (NMR) metabolomics, 8 metabolites (fatty acid, propionate, isopropanol, lactate, acetone, valine, methanol and formate) were identified to be significantly dysregulated in ACO subjects when compared to both, asthma and COPD. 2-Propanol 92-103 kallikrein related peptidase 15 Homo sapiens 205-208 34693173-3 2021 This positive effect of 2-propanol on the catalytic reaction can be explained by the solubility of EDA-CA in 2-propanol under the reaction conditions and no formation of solvent-derived byproducts. 2-Propanol 24-34 ectodysplasin A Homo sapiens 99-102 34693173-3 2021 This positive effect of 2-propanol on the catalytic reaction can be explained by the solubility of EDA-CA in 2-propanol under the reaction conditions and no formation of solvent-derived byproducts. 2-Propanol 109-119 ectodysplasin A Homo sapiens 99-102 34693173-4 2021 This catalytic system using the combination of the CeO2 catalyst and the 2-propanol solvent provided 2-imidazolidinone in up to 83% yield on the EDA-CA basis at 413 K under Ar. 2-Propanol 73-83 ectodysplasin A Homo sapiens 145-148 34121403-0 2021 Ni-Foam-Structured Ni-Al2O3 Ensemble as an Efficient Catalyst for Gas-Phase Acetone Hydrogenation to Isopropanol. 2-Propanol 101-112 gastrin Homo sapiens 66-69 34121403-1 2021 The free-standing Ni-Al2O3 ensemble derived from NiAl-layered double hydroxides (NiAl-LDHs) grown onto a Ni-foam has been developed for the exothermic gas-phase acetone hydrogenation to isopropanol. 2-Propanol 186-197 gastrin Homo sapiens 151-154 2552989-0 1989 Effect of propan-2-ol on enzymic and structural properties of elongation factor G. 2-Propanol 10-21 G elongation factor mitochondrial 1 Homo sapiens 62-81 2552989-1 1989 Elongation factor G (EF-G) can support a GTPase activity in vitro even in the absence of ribosomes when propan-2-ol is present [GTPasep; De Vendittis, Masullo & Bocchini (1986) J. Biol. 2-Propanol 104-115 G elongation factor mitochondrial 1 Homo sapiens 0-19 2552989-10 1989 As estimated from fluorescence measurements, in the presence of 20% (v/v) propan-2-ol the value of the dissociation constant of the complex formed between EF-G and 8-anilino-1-naphthalene-sulphonate decreased from 8 to 5 microM; similarly, the number of binding sites on EF-G for the fluorescent probe decreased from 13 to 6. 2-Propanol 74-85 G elongation factor mitochondrial 1 Homo sapiens 271-275 2552989-12 1989 The data support the hypothesis that propan-2-ol induces moderate conformational changes of EF-G that make the catalytic centre accessible to the substrate even in the absence of ribosomes. 2-Propanol 37-48 G elongation factor mitochondrial 1 Homo sapiens 92-96 2552989-1 1989 Elongation factor G (EF-G) can support a GTPase activity in vitro even in the absence of ribosomes when propan-2-ol is present [GTPasep; De Vendittis, Masullo & Bocchini (1986) J. Biol. 2-Propanol 104-115 G elongation factor mitochondrial 1 Homo sapiens 21-25 2552989-4 1989 In the present work the GTPasep activity of EF-G was further studied by investigating (i) the effect of ionic environment on GTPasep and (ii) the influence of propan-2-ol on the molecular structure of EF-G as determined by fluorescence and c.d. 2-Propanol 159-170 G elongation factor mitochondrial 1 Homo sapiens 44-48 2552989-4 1989 In the present work the GTPasep activity of EF-G was further studied by investigating (i) the effect of ionic environment on GTPasep and (ii) the influence of propan-2-ol on the molecular structure of EF-G as determined by fluorescence and c.d. 2-Propanol 159-170 G elongation factor mitochondrial 1 Homo sapiens 201-205 2552989-10 1989 As estimated from fluorescence measurements, in the presence of 20% (v/v) propan-2-ol the value of the dissociation constant of the complex formed between EF-G and 8-anilino-1-naphthalene-sulphonate decreased from 8 to 5 microM; similarly, the number of binding sites on EF-G for the fluorescent probe decreased from 13 to 6. 2-Propanol 74-85 G elongation factor mitochondrial 1 Homo sapiens 155-159 3127944-4 1988 Eighteen hours after alcohol administration (1/2 LD50 dose, po), CS2 microsomal MFO metabolism was significantly enhanced, in order of descending potency, by isopropanol, methanol, and ethanol pretreatments, but not by isobutanol pretreatment. 2-Propanol 158-169 calsyntenin 2 Rattus norvegicus 65-68 2498460-9 1989 Dietary ethanol alone and in combination with isopropanol stimulated an increase in the size of the NAD-pool in larvae, a condition that may favor the activity of ADH. 2-Propanol 46-57 Alcohol dehydrogenase Drosophila melanogaster 163-166 3139586-9 1988 Our results suggest that pentenol (unsaturated secondary alcohol) and isopropanol (saturated secondary alcohol) may be detoxified by slightly different processes (both ADH-activity-dependent), and that pentenone could not be accumulated in the fly but transformed into another compound(s) by means of some ADH-independent mechanism(s). 2-Propanol 70-81 Alcohol dehydrogenase Drosophila melanogaster 168-171 3413838-0 1988 [Effect of isopropanol on the enzymatic activity and stability of thrombin]. 2-Propanol 11-22 coagulation factor II, thrombin Homo sapiens 66-74 3413838-1 1988 Isopropanol is shown to affect considerably the thrombin activity. 2-Propanol 0-11 coagulation factor II, thrombin Homo sapiens 48-56 3413838-4 1988 Isopropanol in the concentration of 25% is able to suppress the thrombin autolysis and therefore it may be used as a reagent which stabilizes thrombin during its storage in the aquatic-salt solutions. 2-Propanol 0-11 coagulation factor II, thrombin Homo sapiens 64-72 3413838-4 1988 Isopropanol in the concentration of 25% is able to suppress the thrombin autolysis and therefore it may be used as a reagent which stabilizes thrombin during its storage in the aquatic-salt solutions. 2-Propanol 0-11 coagulation factor II, thrombin Homo sapiens 142-150 3133959-1 1988 Fatty acids (C12-C18) and their omega- and (omega-1)-hydroxy derivatives, when converted to p-bromophenacyl (PBP) esters, can be completely separated from one another by high pressure liquid chromatography (HPLC) on a silicic acid column using 0.5% (v/v) isopropanol in n-hexane. 2-Propanol 255-266 polycystin 1, transient receptor potential channel interacting Homo sapiens 109-112 3337723-1 1988 Administration of ethanol, dimethylsulphoxide, 2-propanol or imidazole to rats caused 2-7-fold increases in the level of hepatic ethanol-inducible cytochrome P-450 (P-450j), without any concomitant enhancement of corresponding mRNA. 2-Propanol 47-57 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 147-163 3337723-1 1988 Administration of ethanol, dimethylsulphoxide, 2-propanol or imidazole to rats caused 2-7-fold increases in the level of hepatic ethanol-inducible cytochrome P-450 (P-450j), without any concomitant enhancement of corresponding mRNA. 2-Propanol 47-57 cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus 165-171 3337723-3 1988 A correlation was reached between the concentration of Me2SO, ethanol and 2-propanol necessary to maintain P-450j in the cell cultures and their binding affinities to the enzyme. 2-Propanol 74-84 cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus 107-113 2452501-5 1988 The addition of isopropanol increases sharply the stability of thrombin when storing it in the aqueous-salt solutions. 2-Propanol 16-27 coagulation factor II, thrombin Homo sapiens 63-71 3178785-1 1988 Methanol, ethanol and isopropanol were tested for the ability to change effects of chlorinated hydrocarbons on the alanine aminotransferase (ALAT = GPT; EC 2.6.1.2.) 2-Propanol 22-33 glutamic--pyruvic transaminase Rattus norvegicus 148-151 3277532-9 1988 A binary subcomplex consisting of cytochrome f and the Rieske iron-sulfur protein was observed under these conditions by three different methods: (a) hydroxyapatite chromatography; (b) extraction with an isopropanol/water/trifluoroacetic acid mixture; and (c) gel filtration in the presence of low SDS concentrations. 2-Propanol 204-215 apocytochrome f precursor Spinacia oleracea 34-46 3123426-4 1987 After isopropanol ingestion, the flies of all three Adh genotypes shown much higher sensitivity to ethanol than to isopropanol although the opposite results were observed in flies not pretreated with isopropanol. 2-Propanol 6-17 Alcohol dehydrogenase Drosophila melanogaster 52-55 3123426-4 1987 After isopropanol ingestion, the flies of all three Adh genotypes shown much higher sensitivity to ethanol than to isopropanol although the opposite results were observed in flies not pretreated with isopropanol. 2-Propanol 115-126 Alcohol dehydrogenase Drosophila melanogaster 52-55 3123426-4 1987 After isopropanol ingestion, the flies of all three Adh genotypes shown much higher sensitivity to ethanol than to isopropanol although the opposite results were observed in flies not pretreated with isopropanol. 2-Propanol 115-126 Alcohol dehydrogenase Drosophila melanogaster 52-55 3117619-2 1987 The Adh genotypes differ in the maximum oxidation rates of propan-2-ol into acetone in vivo. 2-Propanol 59-70 alcohol dehydrogenase Drosophila simulans 4-7 3451009-3 1987 Apolipoprotein- (apo) B was separated by the method of isopropanol precipitation. 2-Propanol 55-66 apolipoprotein B Rattus norvegicus 0-23 3117619-5 1987 The rank order of the maximum rates of the ADHs in elimination of propan-2-ol, as well as ethanol, is ADH-71k greater than ADH-F greater than ADH-S greater than simulans-ADH. 2-Propanol 66-77 Alcohol dehydrogenase Drosophila melanogaster 43-46 3117619-5 1987 The rank order of the maximum rates of the ADHs in elimination of propan-2-ol, as well as ethanol, is ADH-71k greater than ADH-F greater than ADH-S greater than simulans-ADH. 2-Propanol 66-77 Alcohol dehydrogenase Drosophila melanogaster 102-105 3117619-5 1987 The rank order of the maximum rates of the ADHs in elimination of propan-2-ol, as well as ethanol, is ADH-71k greater than ADH-F greater than ADH-S greater than simulans-ADH. 2-Propanol 66-77 Alcohol dehydrogenase Drosophila melanogaster 102-105 3117619-5 1987 The rank order of the maximum rates of the ADHs in elimination of propan-2-ol, as well as ethanol, is ADH-71k greater than ADH-F greater than ADH-S greater than simulans-ADH. 2-Propanol 66-77 alcohol dehydrogenase Drosophila simulans 102-105 3772252-0 1986 Measurement of apolipoprotein B radioactivity in whole blood plasma by precipitation with isopropanol. 2-Propanol 90-101 apolipoprotein B Oryctolagus cuniculus 15-31 3772252-2 1986 Radiolabeled apolipoprotein B is precipitated from plasma diluted 15- to 30-fold in the presence of carrier low density lipoproteins by 50% isopropanol. 2-Propanol 140-151 apolipoprotein B Oryctolagus cuniculus 13-29 3772252-3 1986 The amount of radioiodine in apoB is estimated from the difference between total radioiodine concentration in whole plasma and the fraction soluble in 50% isopropanol. 2-Propanol 155-166 apolipoprotein B Oryctolagus cuniculus 29-33 3007457-0 1986 The elongation factor G carries a catalytic site for GTP hydrolysis, which is revealed by using 2-propanol in the absence of ribosomes. 2-Propanol 96-106 G elongation factor mitochondrial 1 Homo sapiens 4-23 3906004-4 1985 ApoB in each lipoprotein fraction was selectively precipitated using isopropanol in order to calculate specific activity. 2-Propanol 69-80 apolipoprotein B Sus scrofa 0-4 3004333-8 1986 Results obtained in conjunction with these studies demonstrated that the thioredoxin m-linked activation of NADP-malate dehydrogenase in selectively enhanced by the presence of halide ions (e.g., chloride) and by an organic solvent (e.g., 2-propanol). 2-Propanol 239-249 LOC101027257 Zea mays 73-84 3877728-7 1985 Storage of either form of L-cell CSF at pH 2.1, in the presence of acetonitrile or isopropanol, destroyed the biological activity. 2-Propanol 83-94 colony stimulating factor 2 (granulocyte-macrophage) Mus musculus 33-36 2983763-8 1985 At 0 degree C 2-propanol and ethanol are more potent tools for membrane modification than Triton X-114 and release 88% and 86% latent activity corresponding to an activation of the glucose-6-phosphatase of about 850% and 700%, respectively. 2-Propanol 14-24 glucose-6-phosphatase catalytic subunit 1 Rattus norvegicus 181-202 2579844-1 1985 Administration of isopropanol (2.5 ml/kg, po) or chlordecone (15.2 mg/kg, po) potentiated the release of glutamic oxaloacetic transaminase (GOT) into serum 17- or 7-fold, respectively, in rats exposed subsequently to 30 microliter CCl4/kg, po. 2-Propanol 18-29 C-C motif chemokine ligand 4 Rattus norvegicus 231-235 2579844-2 1985 Hepatocytes isolated from isopropanol-treated rats, incubated with low concentrations of CCl4 (0.3 or 0.9 mM), did not have significant increase in the amount of GOT released after 30 min compared to control cells exposed to CCl4. 2-Propanol 26-37 C-C motif chemokine ligand 4 Rattus norvegicus 89-93 2579844-3 1985 However, at 3 hr cells from isopropanol-treated rats released 10- or 3-fold more GOT when exposed to 0.3 or 0.9 mM CCl4, respectively, than control cells exposed to CCl4. 2-Propanol 28-39 C-C motif chemokine ligand 4 Rattus norvegicus 115-119 2579844-3 1985 However, at 3 hr cells from isopropanol-treated rats released 10- or 3-fold more GOT when exposed to 0.3 or 0.9 mM CCl4, respectively, than control cells exposed to CCl4. 2-Propanol 28-39 C-C motif chemokine ligand 4 Rattus norvegicus 165-169 2579844-6 1985 These results indicate that the potentiation by isopropanol or chlordecone of CCl4-induced release of GOT from liver is retained through the procedures of cell isolation. 2-Propanol 48-59 C-C motif chemokine ligand 4 Rattus norvegicus 78-82 3969680-10 1985 Our observations suggest that cytochrome P-450-mediated metabolic activation of n-hexane in the kidneys may have toxicological relevance in addition to liver metabolism, and that coexposure to isopropanol and n-hexane may represent an enhancement of the health hazard from n-hexane, possibly due to the isopropanol metabolite acetone. 2-Propanol 193-204 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 30-46 3932822-1 1985 An electrophoretic mobility variant of phenoloxidase in a lz stock of Drosophila melanogaster was identified as the A3 component of the phenoloxidase complex by using two different activators to study enzyme activity-natural activator isolated from pupae and 50% 2-propanol. 2-Propanol 263-273 Phox Drosophila melanogaster 39-52 3932822-1 1985 An electrophoretic mobility variant of phenoloxidase in a lz stock of Drosophila melanogaster was identified as the A3 component of the phenoloxidase complex by using two different activators to study enzyme activity-natural activator isolated from pupae and 50% 2-propanol. 2-Propanol 263-273 Phox Drosophila melanogaster 136-149 3969680-10 1985 Our observations suggest that cytochrome P-450-mediated metabolic activation of n-hexane in the kidneys may have toxicological relevance in addition to liver metabolism, and that coexposure to isopropanol and n-hexane may represent an enhancement of the health hazard from n-hexane, possibly due to the isopropanol metabolite acetone. 2-Propanol 303-314 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 30-46 6143322-0 1984 Changes in rat liver metallothionein and metallothionein mRNA induced by isopropanol. 2-Propanol 73-84 metallothionein-like protein 1 Triticum aestivum 21-36 6719461-3 1984 Pretreatment with acetone or isopropanol (2.5 ml/kg) and 2 days of fasting caused a 2-fold potentiation of NDMA-induced plasma GPT elevation, whereas streptozotocin-induced diabetes caused a 4.6-fold potentiation. 2-Propanol 29-40 glutamic--pyruvic transaminase Rattus norvegicus 127-130 6143322-0 1984 Changes in rat liver metallothionein and metallothionein mRNA induced by isopropanol. 2-Propanol 73-84 metallothionein-like protein 1 Triticum aestivum 41-56 6143322-2 1984 A maximal increase in hepatic metallothionein was observed 16 hr after isopropanol. 2-Propanol 71-82 metallothionein-like protein 1 Triticum aestivum 30-45 6143322-10 1984 These methods suggested the maximum metallothionein mRNA level in total RNA extract occurred about 8 hr after administration of isopropanol. 2-Propanol 128-139 metallothionein-like protein 1 Triticum aestivum 36-51 6143322-11 1984 Similarly, when metallothionein mRNA levels were quantitated using dot blot hybridization to [32P]cDNA for mouse metallothionein I, maximum metallothionein mRNA appeared 8 hr after isopropanol administration. 2-Propanol 181-192 metallothionein-like protein 1 Triticum aestivum 16-31 6143322-11 1984 Similarly, when metallothionein mRNA levels were quantitated using dot blot hybridization to [32P]cDNA for mouse metallothionein I, maximum metallothionein mRNA appeared 8 hr after isopropanol administration. 2-Propanol 181-192 metallothionein 1 Mus musculus 113-130 6143322-11 1984 Similarly, when metallothionein mRNA levels were quantitated using dot blot hybridization to [32P]cDNA for mouse metallothionein I, maximum metallothionein mRNA appeared 8 hr after isopropanol administration. 2-Propanol 181-192 metallothionein-like protein 1 Triticum aestivum 113-128 6143322-12 1984 The overall response of these parameters in rats suggest that isopropanol administration leads to an inflammatory-like response that, with respect to zinc metabolism, has elements which are independent of the adrenal gland, but involve transcriptional regulation of the metallothionein gene in liver. 2-Propanol 62-73 metallothionein-like protein 1 Triticum aestivum 270-285 6194011-4 1983 Isopropanol dissociated complexes of alpha 1-antitrypsin or alpha 2-macroglobulin with trypsin preformed in vitro. 2-Propanol 0-11 serpin family A member 1 Homo sapiens 37-56 6362655-12 1983 ADH-2 is somewhat better at oxidizing ethanol relative to 2-propanol as compared to ADH-1. 2-Propanol 58-68 alcohol dehydrogenase 2 Drosophila mojavensis 0-5 6636185-0 1983 Isopropanol enhancement of cytochrome P-450-dependent monooxygenase activities and its effects on carbon tetrachloride intoxication. 2-Propanol 0-11 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 27-43 6636185-1 1983 Acute or chronic treatment of rats with isopropanol caused a significant increase in hepatic cytochrome P-450 content and a two- to threefold increase in aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities, but no significant change in ethylmorphine N-demethylase or benzo(a)pyrene hydroxylase activity. 2-Propanol 40-51 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 93-109 6636185-2 1983 In rats treated with isopropanol and challenged with CCl4, liver toxicity of CCl4 was characteristically potentiated, as assessed by elevation of serum glutamic-pyruvic transaminase (SGPT) levels. 2-Propanol 21-32 C-C motif chemokine ligand 4 Rattus norvegicus 53-57 6636185-2 1983 In rats treated with isopropanol and challenged with CCl4, liver toxicity of CCl4 was characteristically potentiated, as assessed by elevation of serum glutamic-pyruvic transaminase (SGPT) levels. 2-Propanol 21-32 C-C motif chemokine ligand 4 Rattus norvegicus 77-81 6636185-3 1983 Isopropanol pretreatment also potentiated CCl4-induced damage to the hepatic monooxygenase system. 2-Propanol 0-11 C-C motif chemokine ligand 4 Rattus norvegicus 42-46 6636185-4 1983 In addition to a decrease in cytochrome P-450, rats treated with isopropanol and challenged with CCl4 showed a nonspecific decrease not only in aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities, but also in ethylmorphine N-demethylase, benzo(a)pyrene hydroxylase, and NADPH-cytochrome c reductase activities. 2-Propanol 65-76 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 29-45 6636185-4 1983 In addition to a decrease in cytochrome P-450, rats treated with isopropanol and challenged with CCl4 showed a nonspecific decrease not only in aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities, but also in ethylmorphine N-demethylase, benzo(a)pyrene hydroxylase, and NADPH-cytochrome c reductase activities. 2-Propanol 65-76 C-C motif chemokine ligand 4 Rattus norvegicus 97-101 6636185-6 1983 The electrophoretic results showed that isopropanol pretreatment markedly potentiated the CCl4-caused destruction of cytochrome P-450 hemeproteins. 2-Propanol 40-51 C-C motif chemokine ligand 4 Rattus norvegicus 90-94 6636185-6 1983 The electrophoretic results showed that isopropanol pretreatment markedly potentiated the CCl4-caused destruction of cytochrome P-450 hemeproteins. 2-Propanol 40-51 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 117-133 6636185-7 1983 The data strongly suggest that isopropanol increases one or more forms of cytochrome P-450 which selectively enhance the metabolism of CCl4 to an active metabolite. 2-Propanol 31-42 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 74-90 6636185-7 1983 The data strongly suggest that isopropanol increases one or more forms of cytochrome P-450 which selectively enhance the metabolism of CCl4 to an active metabolite. 2-Propanol 31-42 C-C motif chemokine ligand 4 Rattus norvegicus 135-139 6314604-0 1983 Enhanced inhibition of hepatic microsomal calcium pump activity by CCl4 treatment of isopropanol-pretreated rats. 2-Propanol 85-96 C-C motif chemokine ligand 4 Rattus norvegicus 67-71 6314604-1 1983 Pretreatment of rats with isopropanol enhanced both hepatotoxicity and calcium pump inhibition after CCl4 exposure in vivo or in vitro. 2-Propanol 26-37 C-C motif chemokine ligand 4 Rattus norvegicus 101-105 6314604-3 1983 CCl4 hepatotoxicity, judged as increased appearance of glutamic-pyruvate transaminase in serum, was enhanced by isopropanol pretreatment. 2-Propanol 112-123 C-C motif chemokine ligand 4 Rattus norvegicus 0-4 6314604-4 1983 Pretreatment of rats with isopropanol made CCl4 as much as 20- to 30-fold more potent as an inhibitor of the calcium pump. 2-Propanol 26-37 C-C motif chemokine ligand 4 Rattus norvegicus 43-47 6314604-5 1983 Inhibition of another endoplasmic reticulum enzyme, glucose 6-phosphatase, was also enhanced by isopropanol pretreatment. 2-Propanol 96-107 glucose-6-phosphatase catalytic subunit 1 Rattus norvegicus 52-73 6314604-6 1983 In contrast to the effect of CCl4 in control animals, in isopropanol-pretreated rats given CCl4, depletion of liver glutathione was observed. 2-Propanol 57-68 C-C motif chemokine ligand 4 Rattus norvegicus 29-33 6314604-6 1983 In contrast to the effect of CCl4 in control animals, in isopropanol-pretreated rats given CCl4, depletion of liver glutathione was observed. 2-Propanol 57-68 C-C motif chemokine ligand 4 Rattus norvegicus 91-95 6314604-7 1983 Altered CCl4 metabolism in isopropanol-pretreated animals may result in production of increased amounts of phosgene (or other metabolites) responsible for inhibition of the liver microsome calcium pump and glutathione depletion. 2-Propanol 27-38 C-C motif chemokine ligand 4 Rattus norvegicus 8-12 6194011-4 1983 Isopropanol dissociated complexes of alpha 1-antitrypsin or alpha 2-macroglobulin with trypsin preformed in vitro. 2-Propanol 0-11 alpha-2-macroglobulin Homo sapiens 60-81 6631250-0 1983 Isopropanol precipitation method for the determination of apolipoprotein B specific activity and plasma concentrations during metabolic studies of very low density lipoprotein and low density lipoprotein apolipoprotein B. 2-Propanol 0-11 apolipoprotein B Homo sapiens 58-74 6631250-0 1983 Isopropanol precipitation method for the determination of apolipoprotein B specific activity and plasma concentrations during metabolic studies of very low density lipoprotein and low density lipoprotein apolipoprotein B. 2-Propanol 0-11 apolipoprotein B Homo sapiens 204-220 6631250-8 1983 Furthermore, the isopropanol method has been demonstrated to yield consistent data for apoB specific activities in a study of VLDL, IDL, and LDL metabolism. 2-Propanol 17-28 apolipoprotein B Homo sapiens 87-91 20993177-0 1946 Effect of insulin, insulin-dextrose, and water diuresis on metabolism of isopropyl alcohol. 2-Propanol 73-90 insulin Homo sapiens 10-17 6281449-1 1982 Acute oral pretreatment of rats with isopropanol or acetone results in a dose-related potentiation of CCl4 hepatotoxicity. 2-Propanol 37-48 C-C motif chemokine ligand 4 Rattus norvegicus 102-106 7095079-6 1982 Dipyridamole was also effective when CCl4 toxicity was enhanced by isopropanol. 2-Propanol 67-78 C-C motif chemokine ligand 4 Rattus norvegicus 37-41 7187061-1 1982 The effect of 1-propanol, 2-propanol, n-butanol, ethanol and methanol an sorbitol dehydrogenase activity was assayed. 2-Propanol 26-36 sorbitol dehydrogenase Homo sapiens 73-95 6797990-0 1981 Drosophila alcohol dehydrogenase: detoxification of isopropanol and acetone, substances not used in energy metabolism. 2-Propanol 52-63 Alcohol dehydrogenase Drosophila melanogaster 11-32 6279382-3 1981 It was found that treatment of fasted rats with isopropanol or ethanol potentiated the increase of serum glutamic oxaloacetic transaminase elicited by CCl4. 2-Propanol 48-59 C-C motif chemokine ligand 4 Rattus norvegicus 151-155 32928-6 1978 The interaction of the alcohols with cytochrome P-450 in phosphate buffer pH = 6,0 in the detergents absence is characterized by one dissociation constant for MeOH, EtOH, n-BuOH and cyclohexanol and by two dissociation constants for i-PrOH, i-BuOH and tert.-BuOH. 2-Propanol 233-239 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 37-53 3152-12 1975 The small accleration in irreversible binding in liver microsomes from rats pretreated with isopropanol is not proportional to the high increase of CCl4 toxicity. 2-Propanol 92-103 C-C motif chemokine ligand 4 Rattus norvegicus 148-152 21064419-0 1946 The effect of insulin, insulin-destrose, and water diuresis on the metabolism of isopropyl alcohol. 2-Propanol 81-98 insulin Homo sapiens 14-21 21064419-0 1946 The effect of insulin, insulin-destrose, and water diuresis on the metabolism of isopropyl alcohol. 2-Propanol 81-98 insulin Homo sapiens 23-30 7002369-0 1980 Effects of di-isopropylfluorophosphate and isopropanol on the measurement of plasma renin activity. 2-Propanol 43-54 renin Ovis aries 84-89 7002369-7 1980 The organic solvent isopropanol, which is required to dilute the DFP, appeared responsible for this phenomenon, for when the isopropanol alone, in concentrations of 20 and 40 microliter/ml, was added to stored frozen plasma it decreased plasma renin activity from 3.6 +/- 0.3 to 2.2 +/- 0.1 and 0.6 +/- 0.1 ng . 2-Propanol 20-31 renin Ovis aries 244-249 7002369-7 1980 The organic solvent isopropanol, which is required to dilute the DFP, appeared responsible for this phenomenon, for when the isopropanol alone, in concentrations of 20 and 40 microliter/ml, was added to stored frozen plasma it decreased plasma renin activity from 3.6 +/- 0.3 to 2.2 +/- 0.1 and 0.6 +/- 0.1 ng . 2-Propanol 125-136 renin Ovis aries 244-249 7002369-10 1980 Correspondingly, plasma renin substrate concentrations were decreased to 71% and 6% of control, indicating that the renin activity reductions produced by isopropanol were due to its denaturation of substrate. 2-Propanol 154-165 renin Ovis aries 24-29 7002369-10 1980 Correspondingly, plasma renin substrate concentrations were decreased to 71% and 6% of control, indicating that the renin activity reductions produced by isopropanol were due to its denaturation of substrate. 2-Propanol 154-165 renin Ovis aries 116-121 6772467-0 1980 Effect of ethanol and isopropanol on the activity of alcohol dehydrogenase, viability and life-span in Drosophila melanogaster and Drosophila funebris. 2-Propanol 22-33 Alcohol dehydrogenase Drosophila melanogaster 53-74 6999875-1 1980 The rates of oxidation of ethanol and isopropanol by purified rat liver alcohol dehydrogenase were determined in vitro and compared to the rates of metabolism in vivo in order to estimate the extent to which alcohol dehydrogenase activity limits ethanol metabolism. 2-Propanol 38-49 aldo-keto reductase family 1 member A1 Rattus norvegicus 72-93 6999875-5 1980 Since the ratio of rates for isopropanol is about the same in vitro and in vivo, it appears that alcohol dehydrogenase activity is the predominant rate-limiting factor in isopropanol metabolism. 2-Propanol 29-40 aldo-keto reductase family 1 member A1 Rattus norvegicus 97-118 6999875-5 1980 Since the ratio of rates for isopropanol is about the same in vitro and in vivo, it appears that alcohol dehydrogenase activity is the predominant rate-limiting factor in isopropanol metabolism. 2-Propanol 171-182 aldo-keto reductase family 1 member A1 Rattus norvegicus 97-118 836624-0 1977 Instability of the oxy form of sickle hemoglobin and of methemoglobin in isopropanol. 2-Propanol 73-84 hemoglobin subunit gamma 2 Homo sapiens 56-69 1116333-0 1975 Modifications of plasma post-heparin lipolytic activity and tissue lipoprotein lipase activity induced in the rat by acute administration of ethanol or propan-2-ol. 2-Propanol 152-163 lipoprotein lipase Rattus norvegicus 67-85 1116333-4 1975 An increase of adipose tissue lipoprotein lipase (LLA) and a decrease of heart LLA occurred in isopropanol-treated animals, whereas no significant changes were found in these activities after ethanol administration. 2-Propanol 95-106 lipoprotein lipase Rattus norvegicus 30-48 1116333-4 1975 An increase of adipose tissue lipoprotein lipase (LLA) and a decrease of heart LLA occurred in isopropanol-treated animals, whereas no significant changes were found in these activities after ethanol administration. 2-Propanol 95-106 lipoprotein lipase Rattus norvegicus 50-53 1116333-4 1975 An increase of adipose tissue lipoprotein lipase (LLA) and a decrease of heart LLA occurred in isopropanol-treated animals, whereas no significant changes were found in these activities after ethanol administration. 2-Propanol 95-106 lipoprotein lipase Rattus norvegicus 79-82 1116333-9 1975 It is suggested that the changes in tissue LLA produced by isopropanol are mediated by the rise in blood glucose. 2-Propanol 59-70 lipoprotein lipase Rattus norvegicus 43-46 4694348-0 1973 Effect of isopropanol on CCl 4 -induced changes in perfused rat liver hemodynamics. 2-Propanol 10-21 C-C motif chemokine ligand 4 Rattus norvegicus 25-30 13576384-0 1958 Coma in a child following use of isopropyl alcohol in sponging. 2-Propanol 33-50 COMA Homo sapiens 0-4 20993177-0 1946 Effect of insulin, insulin-dextrose, and water diuresis on metabolism of isopropyl alcohol. 2-Propanol 73-90 insulin Homo sapiens 19-26 33849356-0 2021 Severe hand sanitiser (isopropanol) toxicity managed with continuous venovenous haemodiafiltration and angiotensin II. 2-Propanol 23-34 angiotensinogen Homo sapiens 103-117 32638314-4 2021 This is due to the generation of photo-active reactive oxygen species (HO and HO2 -/O2 -) under photolysis in STP effluent, as verified by experiments in the presence of 2-propanol and chloroform. 2-Propanol 171-181 heme oxygenase 2 Homo sapiens 79-82 33914523-4 2021 Compared to the standard acetonitrile enriched nitrogen gas, isopropanol showed the highest increase in regards to peak areas. 2-Propanol 61-72 gastrin Homo sapiens 56-59 33914523-9 2021 In conclusion, isopropanol enriched DEN gas greatly improves the detection of both N-and O-glycan species and their tandem mass spectra, particularly for the early eluting species whose ionization in the absence of DEN gas is hindered by low organic concentrations. 2-Propanol 15-26 gastrin Homo sapiens 40-43 33914523-9 2021 In conclusion, isopropanol enriched DEN gas greatly improves the detection of both N-and O-glycan species and their tandem mass spectra, particularly for the early eluting species whose ionization in the absence of DEN gas is hindered by low organic concentrations. 2-Propanol 15-26 gastrin Homo sapiens 219-222 32986270-3 2021 Upon isopropanol guest inclusion, spin conversion of ~66 % low-spin abundance is attained by ~3 GPa. 2-Propanol 5-16 spindlin 1 Homo sapiens 34-38 33869963-0 2021 Synthesis of FAU-Zeolite Membrane by a Secondary Growth Method: Influence of Seeding on Membrane Growth and Its Performance in the Dehydration of Isopropyl Alcohol-Water Mixture. 2-Propanol 146-163 FAU ubiquitin like and ribosomal protein S30 fusion Homo sapiens 13-16 33427846-5 2021 The obtained beta-AG microrods obtained in Py system can form reversible 1D assembly in water after being treated in organic solvents such as ethanol, acetone and isopropanol, which have high solubility in water. 2-Propanol 163-174 N-methylpurine DNA glycosylase Homo sapiens 13-20 32986270-3 2021 Upon isopropanol guest inclusion, spin conversion of ~66 % low-spin abundance is attained by ~3 GPa. 2-Propanol 5-16 spindlin 1 Homo sapiens 63-67 32708548-5 2020 Thus, for TFC membrane on the PAN-4 substrate the optimal transport characteristics in pervaporation dehydration of isopropanol (12-90 wt.% water) were achieved: 0.22-1.30 kg/(m2h), 99.9 wt.% water in the permeate. 2-Propanol 116-127 NLR family pyrin domain containing 8 Homo sapiens 30-35 33245541-0 2021 Gas-phase isopropanol degradation by nonthermal plasma combined with Mn-Cu/-Al2O3. 2-Propanol 10-21 gastrin Homo sapiens 0-3 33245541-5 2021 In addition, the effect of the carrier gas oxygen content (0%, 20%, and 100%) on IPA conversion and intermediate and carbon dioxide selectivity was also investigated. 2-Propanol 81-84 gastrin Homo sapiens 39-42 33171184-8 2021 The distribution function of the adsorption energy sites obtained with isopropanol revealed the decrease in the number of the high energy sites with increase of CS/Bt mass ratio. 2-Propanol 71-82 citrate synthase Homo sapiens 161-163 32760982-12 2020 For C18 UHPLC-MS plasma lipidomics, monophasic 100% isopropanol had the highest detection response of all annotated lipid classes with high reproducibility. 2-Propanol 52-63 Bardet-Biedl syndrome 9 Homo sapiens 4-7 32687705-5 2020 In this study we report the gas-phase association energies, enthalpies, and entropies for protonated phenylalanine ion clustered with three neutral vapor molecules: 2-propanol, 1-butanol, and 2-pentanol based upon measurements at temperatures ranging from 120 oC to 180 oC. 2-Propanol 165-175 gastrin Homo sapiens 28-31 32117233-5 2020 Here we report that similar short-chain alcohols, such as ethanol, propanol and isopropanol, share the same property of upregulating GILZ gene expression, and blunt cell inflammatory response in vitro. 2-Propanol 80-91 TSC22 domain family member 3 Homo sapiens 133-137 32497192-5 2020 The carboxylation of isopropanol begins with conversion to acetone via an alcohol dehydrogenase. 2-Propanol 21-32 aldo-keto reductase family 1 member A1 Homo sapiens 74-95 32331653-11 2020 Both ethanol and isopropanol at 50% and 80% concentration proved to be effective in removing flavour compounds in PPEF with some modifications on the chemical compositions, protein functionalities and quality. 2-Propanol 17-28 protein phosphatase with EF-hand domain 1 Homo sapiens 114-118 32331653-3 2020 PPEF was treated with ethanol or isopropanol at three different concentrations (20%, 50%, and 80%) to remove the volatiles related to unpleasant beany, earthy and astringent flavours. 2-Propanol 33-44 protein phosphatase with EF-hand domain 1 Homo sapiens 0-4 32548400-4 2020 Addition of isopropanol could stabilize the pollution grade of particles with size >=30 mum (c) at the same level, which is most obviously affected by free water without isopropanol. 2-Propanol 12-23 latexin Homo sapiens 88-91 32035445-0 2020 Surface chemistry of 2-propanol and O2 mixtures on SnO2(110) studied with ambient-pressure x-ray photoelectron spectroscopy. 2-Propanol 21-31 strawberry notch homolog 1 Homo sapiens 51-54 31886655-1 2020 Electrochemical and chemical studies reveal that the amido complex (PNHxP)Fe(CO)(H)(X) (FeN 1, x = 0, X = 0; Fe(H)(NH) 2, x = 1, X = H; PNHP = bis[2-(diisopropylphosphino)ethyl]amine) is active for the electrocatalytic oxidation of isopropanol. 2-Propanol 232-243 flap structure-specific endonuclease 1 Homo sapiens 88-93 31886655-5 2020 FeN 1 is active for the electrooxidation of isopropanol in the presence of strong base (i.e., P2) with an onset potential near -1 V versus Fc0/+. 2-Propanol 44-55 flap structure-specific endonuclease 1 Homo sapiens 0-5 31886655-6 2020 By cyclic voltammetry, fast turnover frequencies of 1.7 s-1 for isopropanol oxidation are achieved with FeN 1. 2-Propanol 64-75 flap structure-specific endonuclease 1 Homo sapiens 104-109 31069943-10 2019 RESULTS: Red tinted 2% chlorhexidine gluconate (w/v) with 70% isopropyl alcohol (v/v) was shown to reduce pen mark visibility significantly more than the other solutions used. 2-Propanol 62-79 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 106-109 31464437-9 2019 The majority of the TBS-extracted proteins were annotated with nutrient reservoir activity, while the isopropanol extraction yielded the highest percentage of endopeptidase proteinase inhibitors. 2-Propanol 102-113 endogenous retrovirus group K member 18 Homo sapiens 173-183 31490591-0 2019 Enantioselective Iridium-Catalyzed Allylation of Acetylenic Ketones via 2-Propanol-Mediated Reductive Coupling of Allyl Acetate: C14-C23 of Pladienolide D. Alkyne-Directed Chemo- and Enantioselectivity. 2-Propanol 72-82 nucleolin Homo sapiens 133-136 31160095-5 2019 A sheath liquid composed of isopropanol - water - acetic acid with a flow rate of 10 muL min-1 and mild MS conditions allowed optimal signal intensities. 2-Propanol 28-39 CD59 molecule (CD59 blood group) Homo sapiens 89-94 30391205-0 2018 Identification of a 2-propanol analogue modulating the non-enzymatic function of indoleamine 2,3-dioxygenase 1. 2-Propanol 20-30 indoleamine 2,3-dioxygenase 1 Mus musculus 81-110 31117367-5 2019 When the alcohol added is ethanol, isopropanol, or 1-propanol, the decrease in transition temperature is followed by a region of complete ELP insolubility, and, finally, the emergence of upper-critical solution transition (UCST)-like behavior. 2-Propanol 35-46 nuclear receptor subfamily 5 group A member 1 Homo sapiens 138-141 30592336-2 2019 Herein, with the designed artificial interfaces due to the introduction of water-miscible isopropanol, the gelation of GO is achieved in water at an ultralow concentration (0.1 mg mL-1 , the lowest ever-reported) with a solvothermal treatment. 2-Propanol 90-101 L1 cell adhesion molecule Mus musculus 180-184 30740291-3 2019 The L4-based RuCl3 3H2O system corresponded to the best conversion of PhI (96 %) along with 99 % selectivity to the target product of methyl benzoate as well as the good generality to alkoxycarbonylation of different aryl halides (ArX, X=I and Br) with alcohols MeOH, EtOH, i-PrOH and n-BuOH. 2-Propanol 276-282 glucose-6-phosphate isomerase Homo sapiens 72-75 29901984-4 2018 Using this approach, we predicted that the hydride transfer reaction catalyzed by the enzyme dihydrofolate reductase (DHFR) from Escherichia coli in aqueous mixtures of isopropanol (IPA) with water will decrease by ~3 fold at 20% (v/v) IPA concentration. 2-Propanol 169-180 Dihydrofolate reductase Escherichia coli 93-116 30220200-7 2018 We show that when supported on titania (TiO2), tuning the composition of the Pd/Au nanocrystal surface provides a synergistic effect in the selective oxidation of 2-propanol to acetone in the presence of H2 and O2. 2-Propanol 163-173 relaxin 2 Homo sapiens 204-213 29901984-4 2018 Using this approach, we predicted that the hydride transfer reaction catalyzed by the enzyme dihydrofolate reductase (DHFR) from Escherichia coli in aqueous mixtures of isopropanol (IPA) with water will decrease by ~3 fold at 20% (v/v) IPA concentration. 2-Propanol 169-180 Dihydrofolate reductase Escherichia coli 118-122 29901984-4 2018 Using this approach, we predicted that the hydride transfer reaction catalyzed by the enzyme dihydrofolate reductase (DHFR) from Escherichia coli in aqueous mixtures of isopropanol (IPA) with water will decrease by ~3 fold at 20% (v/v) IPA concentration. 2-Propanol 182-185 Dihydrofolate reductase Escherichia coli 93-116 29901984-4 2018 Using this approach, we predicted that the hydride transfer reaction catalyzed by the enzyme dihydrofolate reductase (DHFR) from Escherichia coli in aqueous mixtures of isopropanol (IPA) with water will decrease by ~3 fold at 20% (v/v) IPA concentration. 2-Propanol 182-185 Dihydrofolate reductase Escherichia coli 118-122 29901984-4 2018 Using this approach, we predicted that the hydride transfer reaction catalyzed by the enzyme dihydrofolate reductase (DHFR) from Escherichia coli in aqueous mixtures of isopropanol (IPA) with water will decrease by ~3 fold at 20% (v/v) IPA concentration. 2-Propanol 236-239 Dihydrofolate reductase Escherichia coli 93-116 29901984-4 2018 Using this approach, we predicted that the hydride transfer reaction catalyzed by the enzyme dihydrofolate reductase (DHFR) from Escherichia coli in aqueous mixtures of isopropanol (IPA) with water will decrease by ~3 fold at 20% (v/v) IPA concentration. 2-Propanol 236-239 Dihydrofolate reductase Escherichia coli 118-122 28248453-1 2017 We report the experimental observation of nonmonotonic changes in the collective hydration of bovine serum albumin (BSA) in the presence of alcohols of varying carbon-chain lengths, that is, ethanol, 2-propanol, and tert-butyl alcohol (TBA), by using terahertz (THz) time domain spectroscopy. 2-Propanol 200-210 albumin Homo sapiens 101-114 28872850-3 2017 The MS signal intensity was improved 600-fold (for standard oligonucleotide dT15) by the isopropanol vapor assisted electrospray, and effective ion-pair LC separation was feasibly coupled with high-sensitive MS detection. 2-Propanol 89-100 anon-4Ce Drosophila melanogaster 76-80 28655383-3 2017 Metabolic acidosis was absent in our patient, presumably because formic acid production is blocked by isopropanol, which inhibits alcohol dehydrogenase. 2-Propanol 102-113 aldo-keto reductase family 1 member A1 Homo sapiens 130-151 28340730-2 2017 The methodology is based on the use of attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) measurement of sample extracts with 2-propanol drying 5microL of the extracts onto the ATR crystal. 2-Propanol 155-165 ATR serine/threonine kinase Homo sapiens 109-112 28340730-2 2017 The methodology is based on the use of attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) measurement of sample extracts with 2-propanol drying 5microL of the extracts onto the ATR crystal. 2-Propanol 155-165 ATR serine/threonine kinase Homo sapiens 206-209 28553537-1 2017 Solvent effects in a series of Fe(iii) spin crossover (SCO) complexes [Fe(qsal-I)2]OTf sol (sol = MeOH 1, EtOH 2, n-PrOH 3, i-PrOH 4, acetone 5 and MeCN 6) are explored. 2-Propanol 124-130 spindlin 1 Homo sapiens 39-43 29565595-3 2018 The SP3 approach was tested in a wide range of experimental scenarios, including (1) binding solvents (acetonitrile, ethanol, isopropanol, acetone), (2) binding pH (acidic vs neutral), (3) solvent/lysate ratios (50-200%, v/v), (4) mixing and rinsing conditions (on-rack vs off-rack rinsing), (5) Enrichment of nondenatured proteins, and (6) capture of individual proteins from noncomplex mixtures. 2-Propanol 126-137 Sp3 transcription factor Homo sapiens 4-7 29185114-1 2017 A 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20) /1,3,5,7-tetranitro-1,3,5,7-tetrazacyclooctane (HMX)-isopropanol (IPA) interfacial model was constructed to investigate the effect of temperature on cocrystal morphology. 2-Propanol 135-138 epithelial membrane protein 1 Homo sapiens 62-67 29185114-11 2017 Graphical Abstract Construction of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20) /1,3,5,7-tetranitro-1,3,5,7-tetrazacyclooctane (HMX)-isopropanol (IPA) interfacial model, analysis, and morphology prediction of cocrystal. 2-Propanol 168-171 epithelial membrane protein 1 Homo sapiens 95-100 29120608-0 2017 Biochemical Gas Sensors (Biosniffers) Using Forward and Reverse Reactions of Secondary Alcohol Dehydrogenase for Breath Isopropanol and Acetone as Potential Volatile Biomarkers of Diabetes Mellitus. 2-Propanol 120-131 aldo-keto reductase family 1 member A1 Homo sapiens 87-108 28975686-1 2017 Milstein"s complex, (PNN)RuHCl(CO), catalyzes the efficient reduction of aryl and alkyl halides under relatively mild conditions by using propan-2-ol and a base. 2-Propanol 138-149 pinin, desmosome associated protein Homo sapiens 21-24 28857344-3 2017 Formation of the monohydride RuH(OAc)(CO)(DiPPF) (4) has been observed by reaction of 3 with iPrOH in the presence of NEt3 at RT through an equilibrium reaction. 2-Propanol 93-98 tetraspanin 2 Homo sapiens 118-122 28782904-8 2017 RESULTS: Olfactory responses to isopropanol with open eyes in addicted patients manifested as increase in alpha-rhythm and beta1-rhythm, with closed eyes presentation of this odorant was accompanied by increase of theta-rhythm in opioid-addicted patients. 2-Propanol 32-43 potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens 123-128 31457582-1 2017 The homogeneous transfer hydrogenation of benzonitrile with 2-propanol or 1,4-butanediol produced N-benzylidene benzylamine (BBA, 85% yield) using 5 mol % [Ni(COD)2] as a catalytic precursor and a mixture of Cy2P(CH2)2PCy2 and Cy2P(CH2)2P(O)Cy2 as ancillary ligands, under mild reaction conditions (120 C, 96 h, tetrahydrofuran). 2-Propanol 60-70 COD2 Homo sapiens 159-164 27010186-2 2016 In this approach, elaborately controlling the reaction temperature and volume ratio of i-PrOH and H2O enabled TaF5 to transform into intermediate coordination complex ions of [TaOF3 2F](2-) and [TaF7](2-), which subsequently produced tantalum oxyfluoride ACHNs via a secondary nucleation and growth due to a stepwise change in hydrolysis rates of the two complex ions. 2-Propanol 87-93 TATA-box binding protein associated factor 5 Homo sapiens 110-114 27682673-2 2016 Methods: After tert-butyl alcohol in the air of the workplace collected with activated carbon tube and desorbed with 2% 2-propanol in CS2, and then separated with DB-FFAP capillary column and detected with flame ionization detector. 2-Propanol 120-130 chorionic somatomammotropin hormone 2 Homo sapiens 134-137 27346174-2 2016 Second-order rate constants (ks and kr) for reactions of ArO( ) and alpha-Toc( ) radicals with the above antioxidants were measured in 2-propanol/water (5:1, v/v) solution at 25.0 C, using single- and double-mixing stopped-flow spectrophotometries, respectively. 2-Propanol 135-145 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 57-60 27145380-4 2016 This trihydride-tetrahydrideborate derivative and its PPh3 counterpart OsH3(kappa(2)-H2BH2)(IPr)(PPh3) (8) can be also obtained in a one-pot procedure, starting from 1 and 2 and using methanol at -60 C instead of 2-propanol as alcoholysis agent. 2-Propanol 214-224 protein phosphatase 4 catalytic subunit Homo sapiens 54-58 27145380-4 2016 This trihydride-tetrahydrideborate derivative and its PPh3 counterpart OsH3(kappa(2)-H2BH2)(IPr)(PPh3) (8) can be also obtained in a one-pot procedure, starting from 1 and 2 and using methanol at -60 C instead of 2-propanol as alcoholysis agent. 2-Propanol 214-224 protein phosphatase 4 catalytic subunit Homo sapiens 97-101 27578266-5 2017 The greatest denaturing effect was always observed for n-propanol (P < 0.001), and in the case of PLA2, the effect of isopropanol was greater than ethanol (P < 0.001). 2-Propanol 121-132 phospholipase A2 group IB Homo sapiens 101-105 28245818-10 2017 Of the solvents tested, incubation of mTG in isopropanol for 24 h at 4 C showed the strongest stabilizing effect with mTG retaining 61 and 72% activity for WT and S2P respectively in 70% isopropanol. 2-Propanol 45-56 protease, serine 3 Mus musculus 38-41 28245818-10 2017 Of the solvents tested, incubation of mTG in isopropanol for 24 h at 4 C showed the strongest stabilizing effect with mTG retaining 61 and 72% activity for WT and S2P respectively in 70% isopropanol. 2-Propanol 45-56 protease, serine 3 Mus musculus 119-122 28245818-10 2017 Of the solvents tested, incubation of mTG in isopropanol for 24 h at 4 C showed the strongest stabilizing effect with mTG retaining 61 and 72% activity for WT and S2P respectively in 70% isopropanol. 2-Propanol 188-199 protease, serine 3 Mus musculus 38-41 28245818-10 2017 Of the solvents tested, incubation of mTG in isopropanol for 24 h at 4 C showed the strongest stabilizing effect with mTG retaining 61 and 72% activity for WT and S2P respectively in 70% isopropanol. 2-Propanol 188-199 protease, serine 3 Mus musculus 119-122 27444263-5 2016 Under visible light irradiation, undoped P25 was inactive contrary to N-doped P25 that successfully degraded 95% of the 4-chlorophenol (after 10 h) and 23% of iso-propanol (after 2.5 h). 2-Propanol 159-171 tubulin polymerization promoting protein Homo sapiens 78-81 27010186-2 2016 In this approach, elaborately controlling the reaction temperature and volume ratio of i-PrOH and H2O enabled TaF5 to transform into intermediate coordination complex ions of [TaOF3 2F](2-) and [TaF7](2-), which subsequently produced tantalum oxyfluoride ACHNs via a secondary nucleation and growth due to a stepwise change in hydrolysis rates of the two complex ions. 2-Propanol 87-93 TATA-box binding protein associated factor 7 Homo sapiens 195-199 26634746-4 2016 Fixation of the bacterial cells with ethanol, 2-propanol, glutaraldehyde, paraformaldehyde, and heat treatment resulted in a significant decrease of alkaline phosphatase, peroxidase, and beta-galactosidase activities. 2-Propanol 46-56 DeoR/GlpR transcriptional regulator Lactobacillus rhamnosus GG 149-169 26634746-4 2016 Fixation of the bacterial cells with ethanol, 2-propanol, glutaraldehyde, paraformaldehyde, and heat treatment resulted in a significant decrease of alkaline phosphatase, peroxidase, and beta-galactosidase activities. 2-Propanol 46-56 Dyp-type peroxidase Lactobacillus rhamnosus GG 171-181 26634746-4 2016 Fixation of the bacterial cells with ethanol, 2-propanol, glutaraldehyde, paraformaldehyde, and heat treatment resulted in a significant decrease of alkaline phosphatase, peroxidase, and beta-galactosidase activities. 2-Propanol 46-56 beta-galactosidase subunit alpha Lactobacillus rhamnosus GG 187-205 26639466-5 2015 The content of primary LPO products in the isopropanol fraction of the plasma progressively decreased with increasing superoxide dismutase and catalase activities in the plasma. 2-Propanol 43-54 lactoperoxidase Rattus norvegicus 23-26 26639466-5 2015 The content of primary LPO products in the isopropanol fraction of the plasma progressively decreased with increasing superoxide dismutase and catalase activities in the plasma. 2-Propanol 43-54 catalase Rattus norvegicus 143-151 26639466-2 2015 We observed accumulation of primary (diene conjugates) and secondary (ketodienes, and conjugated trienes) LPO products in the heptane and isopropanol fractions of blood plasma and a decrease in superoxide dismutase and catalase activities in blood plasma. 2-Propanol 138-149 lactoperoxidase Rattus norvegicus 106-109 26639466-3 2015 In lymphocytes, the concentration of primary, secondary and end-products (Schiff bases) of LPO increased in the isopropanol fraction of lipid extract. 2-Propanol 112-123 lactoperoxidase Rattus norvegicus 91-94 26274605-7 2015 The rate constants for BDE-47 and BDE-28 (9.01 and 17.52 x 10-3 min-1), added to isopropyl alcohol, were very close to those (9.65 and 18.42 x 10-3 min-1) in water, proving the less indirect photolytic contribution of OH in water. 2-Propanol 81-98 CD59 molecule (CD59 blood group) Homo sapiens 64-69 26639466-4 2015 Treatment with erythropoietin was followed by a decrease in the level of primary and end-products of LPO in the isopropanol fraction of lipid extract of the plasma and lymphocytes and an increase in of superoxide dismutase and catalase activities in the plasma. 2-Propanol 112-123 erythropoietin Rattus norvegicus 15-29 26639466-4 2015 Treatment with erythropoietin was followed by a decrease in the level of primary and end-products of LPO in the isopropanol fraction of lipid extract of the plasma and lymphocytes and an increase in of superoxide dismutase and catalase activities in the plasma. 2-Propanol 112-123 lactoperoxidase Rattus norvegicus 101-104 26274605-7 2015 The rate constants for BDE-47 and BDE-28 (9.01 and 17.52 x 10-3 min-1), added to isopropyl alcohol, were very close to those (9.65 and 18.42 x 10-3 min-1) in water, proving the less indirect photolytic contribution of OH in water. 2-Propanol 81-98 CD59 molecule (CD59 blood group) Homo sapiens 148-153 25759519-4 2015 Isopropanol extracts of Artemisia showed the higher DPPH radical scavenging activity and lesser LPS-induced reactive oxygen species productions and increased HO-1 expression through increased nuclear translocation of Nrf2 transcription factor compared to ethanol extracts. 2-Propanol 0-11 heme oxygenase 1 Rattus norvegicus 158-162 26076213-1 2015 Highly stable FAU-type zeolite membrane for the separation of isopropanol (IPA)-water mixture by pervaporation is described. 2-Propanol 62-73 FAU ubiquitin like and ribosomal protein S30 fusion Homo sapiens 14-17 26076213-1 2015 Highly stable FAU-type zeolite membrane for the separation of isopropanol (IPA)-water mixture by pervaporation is described. 2-Propanol 75-78 FAU ubiquitin like and ribosomal protein S30 fusion Homo sapiens 14-17 25759519-4 2015 Isopropanol extracts of Artemisia showed the higher DPPH radical scavenging activity and lesser LPS-induced reactive oxygen species productions and increased HO-1 expression through increased nuclear translocation of Nrf2 transcription factor compared to ethanol extracts. 2-Propanol 0-11 NFE2 like bZIP transcription factor 2 Rattus norvegicus 217-221 25759519-5 2015 The increased expression of HSP70 and decreased expression of endothelin-1 were only increased with isopropanol extracts. 2-Propanol 100-111 heat shock protein family A (Hsp70) member 1B Rattus norvegicus 28-33 25759519-5 2015 The increased expression of HSP70 and decreased expression of endothelin-1 were only increased with isopropanol extracts. 2-Propanol 100-111 endothelin 1 Rattus norvegicus 62-74 25759519-6 2015 A concentration-dependent inhibition of LPS-induced COX-2 and iNOS even at a rather lower concentration than ethanol extract was achieved with isopropanol extracts. 2-Propanol 143-154 cytochrome c oxidase II, mitochondrial Rattus norvegicus 52-57 25759519-6 2015 A concentration-dependent inhibition of LPS-induced COX-2 and iNOS even at a rather lower concentration than ethanol extract was achieved with isopropanol extracts. 2-Propanol 143-154 nitric oxide synthase 2 Rattus norvegicus 62-66 25110916-2 2014 The yield of the corresponding Hiyama coupling products is high up to around 90% in water and isopropanol under an ambient atmosphere in the presence of KOH and NaF. 2-Propanol 94-105 C-X-C motif chemokine ligand 8 Homo sapiens 161-164 28788326-7 2013 Among surface modified chitosans, CMC1 (1.5 M sodium chloroacetate and 75% isopropyl alcohol) showed enhanced surface properties. 2-Propanol 75-92 C-X9-C motif containing 1 Homo sapiens 34-38 24631832-14 2014 2-PpG is a metabolite of 2-propanol, which is quite frequently used in disinfectants. 2-Propanol 25-35 serglycin Homo sapiens 2-5 24513702-5 2014 In our method, each hair sample is first washed twice in isopropanol to remove any CORT from the outside of the hair shaft that has been deposited from sweat or sebum. 2-Propanol 57-68 cortistatin Homo sapiens 83-87 23937335-2 2013 Here, we reported a kinetically controlled self-assembly of C60 assisted by the solvent carbon bisulfide (CS2) into single-crystal ultrathin microribbons of 2C60 3CS2, upon mixing the poor solvent isopropyl alcohol with a C60/CS2 stock solution. 2-Propanol 197-214 chorionic somatomammotropin hormone 2 Homo sapiens 106-109 23937335-2 2013 Here, we reported a kinetically controlled self-assembly of C60 assisted by the solvent carbon bisulfide (CS2) into single-crystal ultrathin microribbons of 2C60 3CS2, upon mixing the poor solvent isopropyl alcohol with a C60/CS2 stock solution. 2-Propanol 197-214 chorionic somatomammotropin hormone 2 Homo sapiens 163-166 24965086-3 2014 When 2 was treated with two equivalents of a base under H2 or in 2-propanol, the hydrido complex 4 containing protic NHC and pyrazolato groups was obtained through metal-ligand cooperation. 2-Propanol 65-75 high mobility group nucleosomal binding domain 4 Homo sapiens 117-120 24177702-6 2014 Complexes 1-6 produced active catalysts in the transfer hydrogenation of ketones in 2-propanol at 82 C. Ruthenium(II) complexes 4-6, containing the PPh3 ligand, exhibited higher catalytic activities than the corresponding ruthenium(III) compounds 1-3. 2-Propanol 84-94 caveolin 1 Homo sapiens 149-153 23703707-0 2013 Characterization by NMR of reactants and products of hydrofluoroether isomers, CF3(CF2)3OCH3 and (CF3)2C(F)CF2OCH3, reacting with isopropyl alcohol. 2-Propanol 130-147 ATPase H+ transporting accessory protein 1 Homo sapiens 83-86 25434188-1 2013 There was studied action of aliphatic alcohols (ethanol, propanol, isopropanol, n-butanol, isobutanol, secbutanol, tretbetanol) and pH on various kinds of reactional capability the serum cholinesterase. 2-Propanol 67-78 butyrylcholinesterase Homo sapiens 187-201 23089953-7 2013 The purified azoreductase retained nearly 100 % activity after incubating in 30 % dimethyl sulfoxide (DMSO), 30 % acetone, 30 % methanol, 20 % ethanol, 20 % isopropanol, and 10 % propanol. 2-Propanol 157-168 NAD(P)H quinone dehydrogenase 1 Homo sapiens 13-25 23634869-4 2013 Without fluid or in large molecule fluids (e.g., isopropanol, ethanol, or fluorinert), the high-pressure behavior intrinsic to Zn(CN)2 is observed; the doubly interpenetrated diamondoid framework structure transforms to a distorted, orthorhombic polymorph, Zn(CN)2-II (Pbca) at ~1.50-1.58 GPa with asymmetric displacement of the bridging CN ligand and reorientation of the Zn(C/N)4 tetrahedra. 2-Propanol 49-60 carnosine dipeptidase 2 Homo sapiens 127-134 23549605-2 2012 One monoester ligand in Ti2(OiPr)6(mu2-OOC-C6H4-COOiPr)(eta1-OOC-C6H4-COOiPr)(iPrOH) is bridging and the other is eta1-coordinated. 2-Propanol 78-83 secreted phosphoprotein 1 Homo sapiens 56-60 23496213-2 2013 The method utilizes the RuHCl(CO)(PPh3)3/iPrOH catalytic system under an Ar atmosphere and provides alpha-branched allylic alpha-amino acid derivatives. 2-Propanol 41-46 caveolin 1 Homo sapiens 34-38 23317771-6 2013 IL-1 can replace water in forming microemulsions with the oil isopropylmyristate (IPM), stabilized by IL-2 (surfactant)+isopropanol (IP as a co-surfactant) like the IL-1/IPM/(IL-2+IP) system. 2-Propanol 120-131 interleukin 1 complex Mus musculus 0-4 23317771-6 2013 IL-1 can replace water in forming microemulsions with the oil isopropylmyristate (IPM), stabilized by IL-2 (surfactant)+isopropanol (IP as a co-surfactant) like the IL-1/IPM/(IL-2+IP) system. 2-Propanol 120-131 interleukin 1 complex Mus musculus 165-169 23075383-2 2013 Solvents that serve as efficient H atom donors (methanol, ethanol, isopropyl alcohol) favor products arising from a net reduction of one or more of the C-Br bonds. 2-Propanol 67-84 carbonyl reductase 1 Homo sapiens 152-156 23470442-3 2013 In this study, immobilized Candida antarctica lipase (Lipozyme 435) was used for the esterification of ricinoleic acid and isopropyl alcohol. 2-Propanol 123-140 PAN0_003d1715 Moesziomyces antarcticus 46-52 23204928-5 2012 The acetone/isopropanol (2:1) system yielded promising results in positive ionization mode, as the maximum number of MS and MS2 features was detected in the extract. 2-Propanol 12-23 MS2 Homo sapiens 124-127 23204928-8 2012 In negative mode as well, the maximum number of MS2 features was detected in methanol/chloroform/water and acetone/isopropanol extracts. 2-Propanol 115-126 MS2 Homo sapiens 48-51 22727644-0 2012 Synthesis and structure-activity relationship studies of 1,3-disubstituted 2-propanols as BACE-1 inhibitors. 2-Propanol 75-86 beta-secretase 1 Homo sapiens 90-96 23590853-6 2013 FINDINGS: SAA was soluble in 70% 2-propanol, 8 M urea and Milli-Q water. 2-Propanol 33-43 serum amyloid A protein Equus caballus 10-13 23089141-3 2013 HbA1c is a useful marker in postmortem biochemistry in determining cause of death in acetonemic cases by allowing to distinguish diabetic ketoacidosis (DKA) from starvation or alcoholic ketoacidosis (AKA) and intoxication by acetone or isopropanol. 2-Propanol 236-247 hemoglobin subunit alpha 1 Homo sapiens 0-4 23549605-2 2012 One monoester ligand in Ti2(OiPr)6(mu2-OOC-C6H4-COOiPr)(eta1-OOC-C6H4-COOiPr)(iPrOH) is bridging and the other is eta1-coordinated. 2-Propanol 78-83 secreted phosphoprotein 1 Homo sapiens 114-118 22779009-5 2012 The microemulsion F-8 (contained 10% of isopropyl myristate as oil phase, 8% of aqueous phase, and 82% of surfactant phase containing Tween 80 and isopropyl alcohol, 3 : 1) showed the highest permeation flux of 0.284 +- 0.003 mug/cm(2)/hour. 2-Propanol 147-164 coagulation factor VIII Homo sapiens 18-21 22083103-2 2012 A combination of catalytic amounts of Pd(OAc)(2) and SPhos in conjunction with CsF in isopropanol effectively affords a variety of coupled products. 2-Propanol 86-97 colony stimulating factor 2 Homo sapiens 79-82 22561882-5 2012 Based on the results of these assays, TA212/pTA411, which was introduced Tfu-Blc fused protein expression system and the synthetic pathway for isopropanol production, was selected for the directly isopropanol production from cellobiose. 2-Propanol 143-154 outer membrane lipoprotein Blc Escherichia coli 77-80 22561882-5 2012 Based on the results of these assays, TA212/pTA411, which was introduced Tfu-Blc fused protein expression system and the synthetic pathway for isopropanol production, was selected for the directly isopropanol production from cellobiose. 2-Propanol 197-208 outer membrane lipoprotein Blc Escherichia coli 77-80 22177827-2 2012 After ingestion or absorption, IPA is converted into acetone by alcohol dehydrogenase. 2-Propanol 31-34 aldo-keto reductase family 1 member A1 Homo sapiens 64-85 21687964-6 2011 Furthermore, the transformant of rELO2 also conferred tolerance to n-butanol, n-propanol, and 2-propanol. 2-Propanol 94-104 ELOVL fatty acid elongase 6 Rattus norvegicus 33-38 22020770-0 2012 The dysregulation of the monocyte/macrophage effector function induced by isopropanol is mediated by the defective activation of distinct members of the AP-1 family of transcription factors. 2-Propanol 74-85 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 153-157 22020770-11 2012 The alcohol-induced cytokine dysregulation was confirmed in a mouse model of isopropanol intoxication in which the production of TNF-alpha in response to LPS challenge was virtually abolished. 2-Propanol 77-88 tumor necrosis factor Mus musculus 129-138 23600284-2 2012 However, competitive inhibition of cytochrome P450 2E1, which metabolizes DENA, by its other substrate, isopropanol, does not weaken, but enhances the toxicity of DENA effect on mice and reduces the number of preneoplastic nodules and liver tumors induced by it. 2-Propanol 104-115 cytochrome P450, family 2, subfamily e, polypeptide 1 Mus musculus 35-54 24900309-2 2011 Molecular dynamics simulation in the isopropanol/water cosolvent environment and in water was employed to investigate Bcl-xL protein, which has a highly flexible, large, and primarily hydrophobic binding site. 2-Propanol 37-48 BCL2 like 1 Homo sapiens 118-124 22389858-1 2011 Insulin-loaded microemulsions for transdermal delivery were developed using isopropyl myristate or oleic acid as the oil phase, Tween 80 as the surfactant, and isopropyl alcohol as the cosurfactant. 2-Propanol 160-177 insulin Capra hircus 0-7 20876523-5 2011 The results show that fixing cells with isopropanol yields the greatest reliability and intensity in both beta-galactosidase staining as well as double staining for beta-galactosidase activity and antibodies. 2-Propanol 40-51 galactosidase, beta 1 Mus musculus 106-124 20876523-5 2011 The results show that fixing cells with isopropanol yields the greatest reliability and intensity in both beta-galactosidase staining as well as double staining for beta-galactosidase activity and antibodies. 2-Propanol 40-51 galactosidase, beta 1 Mus musculus 165-183 20876523-6 2011 In addition, isopropanol and ethanol, but not glutaraldehyde or paraformaldehyde, allow for the isolation of single muscle fibers from the diaphragm and tibialis anterior muscles following postfixed beta-galactosidase staining. 2-Propanol 13-24 galactosidase, beta 1 Mus musculus 199-217 22016696-9 2011 RESULTS: A two-step commercial procedure (Donor Prep Kit; DPK) consisting of 70% isopropyl alcohol followed by tincture of iodine was shown to be a best practice procedure (2-min procedure). 2-Propanol 81-98 TAO kinase 3 Homo sapiens 58-61 20846657-2 2010 The pattern of 1st peak (S(-)) broadening and the 2nd peak (R(+)) compression was observed under mobile phase of hexane (0.1% TFA)/2-propanol (IPA) on a triproline CSP 1, and with other alcohol modifier such as ethanol, 1-propanol, 1-butanol, 2-butanol, and tert-butanol as well. 2-Propanol 131-141 regulator of calcineurin 1 Homo sapiens 164-169 20937259-4 2010 Our initial results showed that methanol, ethanol, isopropanol, isobutanol, and isoamyl alcohol bind in the active site of CYP3A4 and exhibit type I spectra. 2-Propanol 51-62 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 123-129 20632328-4 2010 In particular, we observed that the conversion of the fluorogenic peroxidase substrate Amplex Red by CYP119A1 and BMP was increased by a factor of 38 or 11, respectively, when isopropanol and lauric acid were present in the reaction mixture. 2-Propanol 176-187 bone morphogenetic protein 1 Homo sapiens 114-117 20520869-0 2010 "(eta(6)-arene)Ru(bis-NHC)" complexes for the reduction of CO(2) to formate with hydrogen and by transfer hydrogenation with iPrOH. 2-Propanol 125-130 endothelin receptor type A Homo sapiens 2-5 19942486-0 2010 2-Propanol in the mobile phase reduces the time of analysis of CLA isomers by silver ion-HPLC. 2-Propanol 0-10 selectin P ligand Homo sapiens 63-66 19942486-10 2010 In conclusion, adding 0.05% or 0.1% 2-propanol to the mobile phase shortens the time of analysis of CLA isomers, saves solvents and reduces costs. 2-Propanol 36-46 selectin P ligand Homo sapiens 100-103 20520869-2 2010 The use of one of the "(eta(6)-arene)Ru(bis-NHC)" complexes (labeled as 1 in the text) in the reduction of carbon dioxide with hydrogen affords a maximum TON value of 23000 at 200 degrees C. The same complexes were used in the reduction of carbon dioxide with iPrOH by the transfer hydrogenation methodology. 2-Propanol 260-265 endothelin receptor type A Homo sapiens 24-27 20432237-4 2010 Exposure of ex vivo-intact human skin to a panel of seven irritants (SDS, salicylic acid, phenol, isopropanol, DMSO, TritonX, or benzalkonium chloride) resulted in decreased numbers of CD1a(+) cells in the epidermis and the accumulation of CD1a(+) cells in the dermis. 2-Propanol 98-109 CD1a molecule Homo sapiens 185-189 19966491-3 2009 Both the supernatant and the precipitate fractions were incubated with a phospholipase A(1) (PLA1) from Aspergillus orizae for 3.5 h. The PLA1-treated lipids were extracted with n-hexane/isopropanol, the hexane layer was obtained using a Na(2)SO(4) solution, and the hexane layer was further washed with water. 2-Propanol 187-198 lipase H Homo sapiens 93-97