PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 12162745-3 2002 The isoform-selective inhibitor 4-(2-oxapentadeca-4-yne)phenylpropanoic acid (OPP) was previously shown to inhibit leukocyte-type 12-LOX by a novel mechanism in which it binds to both the ferrous and ferric forms of the enzyme. opp 32-76 lysyl oxidase Homo sapiens 133-136 12162745-3 2002 The isoform-selective inhibitor 4-(2-oxapentadeca-4-yne)phenylpropanoic acid (OPP) was previously shown to inhibit leukocyte-type 12-LOX by a novel mechanism in which it binds to both the ferrous and ferric forms of the enzyme. opp 78-81 lysyl oxidase Homo sapiens 133-136 12162745-7 2002 Titration of ferrous 12-LOX with OPP indicated that it bound to the ferrous form with an apparent K(I) value of 70 +/- 20 nM, suggesting a significantly higher affinity for the ferrous form than for the ferric form of the enzyme. opp 33-36 lysyl oxidase Homo sapiens 24-27 6323289-3 1984 Urinary c-AMP/creatinine in males decreased immediately after the start of OPP-Na treatment and recovered to the normal level within 1 wk. opp 75-78 cathelicidin antimicrobial peptide Rattus norvegicus 8-13