PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
22086331-6	2012	We demonstrate that treatment of seedlings with the mETC inhibitors antimycin A and potassium cyanide under normoxia promotes transient MPK6 and MPK3 activation.	Potassium Cyanide	84-101	MAP kinase 6	Arabidopsis thaliana	136-140
21487704-4	2012	Cells with elevated NQO1 levels were more resistant to death induced by 2-deoxyglucose, potassium cyanide (energetic stress), and lactacystin (proteotoxic stress), but were not protected from being killed by H(2)O(2) and serum withdrawal.	Potassium Cyanide	88-105	NAD(P)H quinone dehydrogenase 1	Homo sapiens	20-24
22391698-9	2012	This SOD likely belongs to the Fe- or Mn-SOD category due to the fact that it was insensitive to potassium cyanide or hydrogen peroxide inhibition, but was potentially weakly stimulated by hydrogen peroxide, and stimulated by Mn(2+)and Fe(2+) ions.	Potassium Cyanide	97-114	superoxide dismutase 2, mitochondrial	Mus musculus	38-44
21779957-3	2012	Pretreatment with potassium cyanide (KCN, a cytochrome pathway inhibitor) greatly increased CN-resistant R and reduced reactive oxygen species (ROS) formation, while application of salicylhydroxamic acid (SHAM, an AOX inhibitor) blocked the AOX activity and enhanced the production of ROS in the plants.	Potassium Cyanide	18-35	acyl-CoA oxidase 1	Homo sapiens	214-217
21779957-3	2012	Pretreatment with potassium cyanide (KCN, a cytochrome pathway inhibitor) greatly increased CN-resistant R and reduced reactive oxygen species (ROS) formation, while application of salicylhydroxamic acid (SHAM, an AOX inhibitor) blocked the AOX activity and enhanced the production of ROS in the plants.	Potassium Cyanide	18-35	acyl-CoA oxidase 1	Homo sapiens	241-244
21779957-3	2012	Pretreatment with potassium cyanide (KCN, a cytochrome pathway inhibitor) greatly increased CN-resistant R and reduced reactive oxygen species (ROS) formation, while application of salicylhydroxamic acid (SHAM, an AOX inhibitor) blocked the AOX activity and enhanced the production of ROS in the plants.	Potassium Cyanide	37-40	acyl-CoA oxidase 1	Homo sapiens	214-217
21779957-3	2012	Pretreatment with potassium cyanide (KCN, a cytochrome pathway inhibitor) greatly increased CN-resistant R and reduced reactive oxygen species (ROS) formation, while application of salicylhydroxamic acid (SHAM, an AOX inhibitor) blocked the AOX activity and enhanced the production of ROS in the plants.	Potassium Cyanide	37-40	acyl-CoA oxidase 1	Homo sapiens	241-244
22970559-3	2012	Vitamin B12 is extracted from the sample in sodium acetate buffer in the presence of potassium cyanide.	Potassium Cyanide	85-102	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	8-11
22086331-6	2012	We demonstrate that treatment of seedlings with the mETC inhibitors antimycin A and potassium cyanide under normoxia promotes transient MPK6 and MPK3 activation.	Potassium Cyanide	84-101	mitogen-activated protein kinase 3	Arabidopsis thaliana	145-149
21064266-7	2010	Depolarizing stimulation up-regulated interaction frequencies between COX and neurochemical genes, whereas impulse blockade with tetrodotoxin or inhibition of COX with KCN down-regulated them in neurons.	Potassium Cyanide	168-171	cytochrome c oxidase subunit 4I1	Mus musculus	159-162
21356207-8	2011	Interestingly, most respiratory inhibitors except KCN induced Cln-1 expression although complex I inhibition by rotenone was most effective on Cln-1 induction.	Potassium Cyanide	50-53	claudin 1	Homo sapiens	62-67
19783484-4	2010	In response to intermittent intravenous injections of KCN, a significant increase in the number of Fos-ir neurons was observed specifically in the lateral intermediate commissural NTS [(LI)NTS (82+/-9 vs. 174+/-16, cell number mean per section)] and lateral caudal commissural NTS [(LC)NTS (71+/-9 vs. 199+/-18, cell number mean per section)].	Potassium Cyanide	54-57	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	99-102
20345763-4	2010	Our results show that initiation of anoxic milieu by the combined action of KCN treatment and glucose deprivation rapidly leads to the association of leader peptide containing trypsinogen 4 constructs to the plasma membrane.	Potassium Cyanide	76-79	serine protease 3	Homo sapiens	176-189
20663895-9	2010	When palmitoyl-CoA was added to the sucrose gradient fractions containing OXPHOS supercomplexes in the presence of potassium cyanide, cytochrome c was reduced.	Potassium Cyanide	115-132	cytochrome c, somatic	Homo sapiens	134-146
19887106-10	2010	Importantly, we find that treatment with potassium cyanide inhibits arrestin translocation in response to light.	Potassium Cyanide	41-58	S-antigen, retina and pineal gland (arrestin)	Mus musculus	68-76
19232048-2	2009	Treatment of Arabidopsis thaliana cell suspension with antimycin A, a respiratory chain complex III inhibitor, resulted in an increase in gdh2 transcripts within 2 h. Inhibition of complex I by rotenone did not influence the transcript level, but treatment with potassium cyanide, a complex IV inhibitor, also increased the transcript content.	Potassium Cyanide	262-279	glutamate dehydrogenase 2	Arabidopsis thaliana	138-142
19146834-5	2009	Our findings revealed that CRH treatments before or 3 and 8 h following KCN insult conferred significant protection against cortical injury, an effect blocked in cultures treated with alpha-helical CRH (9-41) prior to KCN administration.	Potassium Cyanide	72-75	corticotropin releasing hormone	Rattus norvegicus	27-30
19146834-5	2009	Our findings revealed that CRH treatments before or 3 and 8 h following KCN insult conferred significant protection against cortical injury, an effect blocked in cultures treated with alpha-helical CRH (9-41) prior to KCN administration.	Potassium Cyanide	218-221	corticotropin releasing hormone	Rattus norvegicus	27-30
19146834-6	2009	In addition, KOR and DOR blockade significantly reduced CRH-induced neuronal protection observed 3 but not 8 h post-KCN insult.	Potassium Cyanide	116-119	corticotropin releasing hormone	Rattus norvegicus	56-59
19958137-3	2010	Application of exogenous potassium cyanide (KCN, a cytochrome pathway inhibitor) at nonlethal concentrations and NO donor diethylamine NONOate (DEA/NO) to the upper uninoculated leaves greatly induced accumulation of AOX transcript, reduced TMV viral RNA accumulation, and increased the leaf photochemical quantum yield at photosystem II.	Potassium Cyanide	25-42	acyl-CoA oxidase 1	Homo sapiens	217-220
19958137-3	2010	Application of exogenous potassium cyanide (KCN, a cytochrome pathway inhibitor) at nonlethal concentrations and NO donor diethylamine NONOate (DEA/NO) to the upper uninoculated leaves greatly induced accumulation of AOX transcript, reduced TMV viral RNA accumulation, and increased the leaf photochemical quantum yield at photosystem II.	Potassium Cyanide	44-47	acyl-CoA oxidase 1	Homo sapiens	217-220
17351819-8	2008	GhAOX1 was also found to be induced by a variety of stresses stimulation including cold, citrate, SA, KCN and antimycin A in cotton.	Potassium Cyanide	102-105	ubiquinol oxidase 2, mitochondrial-like	Gossypium hirsutum	0-6
18765882-4	2008	The cytotoxicity of KCN was assessed by cell viability assay, morphological observation, lactate dehydrogenase (LDH) release, malondialdehyde (MDA) production, and the activities of superoxide dismutase (SOD) and Na+-K+-ATPase measurements.	Potassium Cyanide	20-23	superoxide dismutase 1	Homo sapiens	182-202
18765882-4	2008	The cytotoxicity of KCN was assessed by cell viability assay, morphological observation, lactate dehydrogenase (LDH) release, malondialdehyde (MDA) production, and the activities of superoxide dismutase (SOD) and Na+-K+-ATPase measurements.	Potassium Cyanide	20-23	superoxide dismutase 1	Homo sapiens	204-207
18765882-9	2008	The KCN - induced decreased cell viability and activities of SOD and Na+-K+-ATPase, as well as increased MDA production were reversed by SSF pre-treatment.	Potassium Cyanide	4-7	superoxide dismutase 1	Homo sapiens	61-64
17940887-3	2008	In the present study, we therefore investigated the effects of NGF on the hypoxic cortical neurons induced by potassium cyanide (KCN).	Potassium Cyanide	110-127	nerve growth factor	Rattus norvegicus	63-66
17940887-7	2008	It might be induced by the inability of NGF to inhibit all injury pathways induced by potassium cyanide.	Potassium Cyanide	86-103	nerve growth factor	Rattus norvegicus	40-43
17980495-3	2007	Over a 20 h exposure KCN increased BNIP3 expression, followed by a concentration-related apoptotic death.	Potassium Cyanide	21-24	BCL2 interacting protein 3	Rattus norvegicus	35-40
17631668-6	2008	The results showed that metabolic inhibitor KCN and P-glycoprotein inhibitor verapamil could increase berberine concentration within the neurons, indicating that efflux of berberine was energy-dependent and P-glycoprotein was likely to be involved.	Potassium Cyanide	44-47	ATP-binding cassette, subfamily B (MDR/TAP), member 1B	Rattus norvegicus	207-221
16935015-6	2007	When we used potassium cyanide to inhibit enzymes downstream of CPTI and thereby degradation of the product, we measured four times more CPTI activity than the previous methods.	Potassium Cyanide	13-30	carnitine palmitoyltransferase 1B	Homo sapiens	64-68
17761681-6	2007	However, the CHO1 transcript was stabilized to a half-life of >45 min in respiratory-deficient (rho(-) and rho(o)) cells, the cox4Delta mutant defective in the cytochrome c oxidase, and wild type cells treated with KCN (a cytochrome c oxidase inhibitor).	Potassium Cyanide	218-221	CDP-diacylglycerol-serine O-phosphatidyltransferase	Saccharomyces cerevisiae S288C	13-17
17404836-7	2007	However, sensitivities of the different enzymes to KCN varied widely and considerably higher concentrations of KCN were required for this effect to be apparent with the rat liver mitochondrial MAO-A than with MAO-B from rat and ox liver.	Potassium Cyanide	51-54	monoamine oxidase A	Rattus norvegicus	193-198
17404836-7	2007	However, sensitivities of the different enzymes to KCN varied widely and considerably higher concentrations of KCN were required for this effect to be apparent with the rat liver mitochondrial MAO-A than with MAO-B from rat and ox liver.	Potassium Cyanide	51-54	monoamine oxidase B	Rattus norvegicus	209-214
17404836-7	2007	However, sensitivities of the different enzymes to KCN varied widely and considerably higher concentrations of KCN were required for this effect to be apparent with the rat liver mitochondrial MAO-A than with MAO-B from rat and ox liver.	Potassium Cyanide	111-114	monoamine oxidase A	Rattus norvegicus	193-198
17404836-7	2007	However, sensitivities of the different enzymes to KCN varied widely and considerably higher concentrations of KCN were required for this effect to be apparent with the rat liver mitochondrial MAO-A than with MAO-B from rat and ox liver.	Potassium Cyanide	111-114	monoamine oxidase B	Rattus norvegicus	209-214
17900002-4	2007	An NADPH-dependent oxidase inhibitor, diphenyl iodonium chloride (DPI), and a myeloperoxidase inhibitor, sodium azide (NaN3), showed remarkable inhibitory effects on ROS generation induced by NP, but an inhibitor against mitochondrial respiratory function, potassium cyanide (KCN), did not exhibit a significant effect.	Potassium Cyanide	257-274	myeloperoxidase	Homo sapiens	78-93
17900002-4	2007	An NADPH-dependent oxidase inhibitor, diphenyl iodonium chloride (DPI), and a myeloperoxidase inhibitor, sodium azide (NaN3), showed remarkable inhibitory effects on ROS generation induced by NP, but an inhibitor against mitochondrial respiratory function, potassium cyanide (KCN), did not exhibit a significant effect.	Potassium Cyanide	276-279	myeloperoxidase	Homo sapiens	78-93
17576767-3	2007	In addition, the block of respiration by antimycin A added to RLM respiring in state 4 conditions, or the addition of H2O2, results in O2 generation, which is blocked by the catalase inhibitors aminotriazole or KCN.	Potassium Cyanide	211-214	catalase	Rattus norvegicus	174-182
17393174-6	2007	Further, we showed that, in cultured SK-N-BE(2)C human neuroblastoma cells, overexpression of PLD2 inhibited cell death by chemical hypoxia induced with potassium cyanide and deoxyglucose.	Potassium Cyanide	153-170	phospholipase D2	Homo sapiens	94-98
17200125-9	2007	When Ndi1 was incorporated into bovine heart submitochondrial particles, the Q-bound form, but not the Q-free form, established the NADH-linked respiratory activity, which was insensitive to piericidin A but inhibited by KCN.	Potassium Cyanide	221-224	NADH-ubiquinone reductase (H(+)-translocating) NDI1	Saccharomyces cerevisiae S288C	5-9
16935015-6	2007	When we used potassium cyanide to inhibit enzymes downstream of CPTI and thereby degradation of the product, we measured four times more CPTI activity than the previous methods.	Potassium Cyanide	13-30	carnitine palmitoyltransferase 1B	Homo sapiens	137-141
16299171-5	2005	In the presence of KCN, leaf tissue of either mutant or wild-type AOX overexpressors showed no increase in oxidative damage, whereas anti-sense lines had levels of damage greater than those observed for untransformed leaves.	Potassium Cyanide	19-22	alternative oxidase 2	Arabidopsis thaliana	66-69
16464535-7	2006	Light-emitting diode pretreatment significantly decreased the expression of caspase-3 elicited by potassium cyanide.	Potassium Cyanide	98-115	caspase 3	Rattus norvegicus	76-85
16464535-8	2006	It also reversed the potassium cyanide-induced increased expression of Bax and decreased expression of Bcl-2 to control levels.	Potassium Cyanide	21-38	BCL2 associated X, apoptosis regulator	Rattus norvegicus	71-74
16464535-8	2006	It also reversed the potassium cyanide-induced increased expression of Bax and decreased expression of Bcl-2 to control levels.	Potassium Cyanide	21-38	BCL2, apoptosis regulator	Rattus norvegicus	103-108
15720138-7	2005	Second, AOX inhibitors (potassium cyanide, menadione, and promethazine) inhibit metabolite formation when N-methylnicotinamide is utilized as an electron donor.	Potassium Cyanide	24-41	aldehyde oxidase 1	Homo sapiens	8-11
15064160-5	2004	Reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase inhibitor, diphenyl iodonium chloride and the myeloperoxidase inhibitor sodium azide (NaN3) showed remarkable inhibitory effects on ROS generation induced by NP, but an inhibitor against mitochondrial respiratory function, potassium cyanide (KCN), did not exhibit significant effect.	Potassium Cyanide	301-318	myeloperoxidase	Homo sapiens	124-139
15064160-5	2004	Reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase inhibitor, diphenyl iodonium chloride and the myeloperoxidase inhibitor sodium azide (NaN3) showed remarkable inhibitory effects on ROS generation induced by NP, but an inhibitor against mitochondrial respiratory function, potassium cyanide (KCN), did not exhibit significant effect.	Potassium Cyanide	320-323	myeloperoxidase	Homo sapiens	124-139
14504927-2	2003	In contrast, in stably transfected HeLa cells expressing rat cardiac connexin43 (Cx43, the main channel-forming protein present in ventricular myocytes), a major part of junctional communication persisted in ATP-depleted conditions, in the presence of a metabolic inhibitor (KCN) or of a broad spectrum inhibitor of protein kinases (H7).	Potassium Cyanide	275-278	gap junction protein, alpha 1	Rattus norvegicus	69-79
14504927-2	2003	In contrast, in stably transfected HeLa cells expressing rat cardiac connexin43 (Cx43, the main channel-forming protein present in ventricular myocytes), a major part of junctional communication persisted in ATP-depleted conditions, in the presence of a metabolic inhibitor (KCN) or of a broad spectrum inhibitor of protein kinases (H7).	Potassium Cyanide	275-278	gap junction protein, alpha 1	Rattus norvegicus	81-85
12460737-1	2002	Cyanide (KCN)-induced generation of reactive oxygen species (ROS) involves cyclooxygenase-2 (COX-2)-mediated reactions in some neurons.	Potassium Cyanide	9-12	prostaglandin-endoperoxide synthase 2	Homo sapiens	75-91
12739149-8	2003	Apoplastic consumption of external NADH by living coleoptiles can be traced back to the superimposed action of two enzymatic reactions, a KCN-sensitive reaction mediated by POD operating in the *OH-forming mode, and a KCN-insensitive reaction with the kinetic properties of a superoxide-producing plasma-membrane NADH oxidase the activity of which can be promoted by auxin.	Potassium Cyanide	138-141	peroxidase 1	Zea mays	173-176
12768344-5	2003	Diphenylene iodonium inhibited about 25% (10 microM DPI) and 40% (100 microM DPI) of this activity, imidazole inhibited about 20%, while KCN, a peroxidase inhibitor, did not show any significant inhibition.	Potassium Cyanide	137-140	peroxidase 1	Zea mays	144-154
12460737-1	2002	Cyanide (KCN)-induced generation of reactive oxygen species (ROS) involves cyclooxygenase-2 (COX-2)-mediated reactions in some neurons.	Potassium Cyanide	9-12	prostaglandin-endoperoxide synthase 2	Homo sapiens	93-98
12460737-3	2002	After treatment with KCN (10-300 microM), COX-2 was expressed in a time- and concentration-dependent manner increasing markedly over a 4-h period.	Potassium Cyanide	21-24	prostaglandin-endoperoxide synthase 2	Homo sapiens	42-47
12460737-5	2002	Correlated with COX-2 up-regulation, KCN induced a time-dependent apoptotic death.	Potassium Cyanide	37-40	prostaglandin-endoperoxide synthase 2	Homo sapiens	16-21
12460737-6	2002	TUNEL staining showed that the COX-2 inhibitor NS-398 (30 microM) blocked KCN-induced apoptosis, whereas the selective COX-1 inhibitor valeryl salicylate did not affect the level of apoptotic cell death.	Potassium Cyanide	74-77	prostaglandin-endoperoxide synthase 2	Homo sapiens	31-36
12460737-9	2002	PCR studies further confirmed that COX-2 expression was increased by KCN.	Potassium Cyanide	69-72	prostaglandin-endoperoxide synthase 2	Homo sapiens	35-40
12460737-10	2002	Antioxidants phenyl-N-test-butylnitrone, superoxide dismutase, and catalase significantly inhibited KCN-induced COX-2 up-regulation and subsequent apoptosis.	Potassium Cyanide	100-103	catalase	Homo sapiens	67-75
12460737-10	2002	Antioxidants phenyl-N-test-butylnitrone, superoxide dismutase, and catalase significantly inhibited KCN-induced COX-2 up-regulation and subsequent apoptosis.	Potassium Cyanide	100-103	prostaglandin-endoperoxide synthase 2	Homo sapiens	112-117
12165299-4	2002	The peroxidase-catalyzed degradation of cell-wall polysaccharides can be inhibited by KCN and superoxide radical (O(2)*) or OH* scavengers.	Potassium Cyanide	86-89	peroxidase	Glycine max	4-14
11312883-9	2001	Tyrosinase activity was inhibited by KCN, thiourea, and SO(2).	Potassium Cyanide	37-40	tyrosinase	Homo sapiens	0-10
12101082-8	2002	Similarly, interrupting the respiratory chain with potassium cyanide reversed the excitatory effect of IL-1 beta on HIF-1 alpha nuclear translocation and activation.	Potassium Cyanide	51-68	interleukin 1 beta	Homo sapiens	103-112
12101082-8	2002	Similarly, interrupting the respiratory chain with potassium cyanide reversed the excitatory effect of IL-1 beta on HIF-1 alpha nuclear translocation and activation.	Potassium Cyanide	51-68	hypoxia inducible factor 1 subunit alpha	Homo sapiens	116-127
11262412-3	2001	1) In the presence of myxothiazol, MOA-stilbene, stigmatellin, or of antimycin added to SMP pretreated with ascorbate and KCN to reduce the high potential components (iron-sulfur protein (ISP) and cytochrome c(1)) of complex III, addition of succinate reduced heme b(H) followed by a slow and partial reduction of heme b(L).	Potassium Cyanide	122-125	cytochrome c1	Bos taurus	197-212
12006386-6	2002	Pretreatment of VSMCs with DPI but not allopurinol or potassium cyanide (KCN) abrogated the activation of ERK1/2.	Potassium Cyanide	73-76	mitogen activated protein kinase 3	Rattus norvegicus	106-112
11045596-4	2000	The IL-1alpha activity reached the highest levels 2 hr after the same KCN treatment.	Potassium Cyanide	70-73	interleukin 1 alpha	Rattus norvegicus	4-13
11045596-6	2000	However, IL-1alpha mRNA induction by KCN was not altered under calcium-free conditions in PC12 cells, indicating its induction was Ca2+-independent.	Potassium Cyanide	37-40	interleukin 1 alpha	Rattus norvegicus	9-18
11045596-7	2000	However, the phosphatidylcholine (PC)-specific phospholipase C (PLC) inhibitor D609 decreased the KCN-induced IL-1alpha mRNA and protein in PC12 cells suggests that PC-PLC might play a role in cytokine induction during hypoxia.	Potassium Cyanide	98-101	interleukin 1 alpha	Rattus norvegicus	110-119
11004581-5	2000	The efficiency of MPO inhibitors to prevent LDL damage increased in the series benzohydroxamic acid < salicylhydroxamic acid < 3-amino-1,2,4-triazole < sodium azide < potassium cyanide < p-hydroxy-benzoic acid hydrazide, while for the HOCl traps the protective efficiency increased in the series glycine < taurine < methionine.	Potassium Cyanide	179-196	myeloperoxidase	Homo sapiens	18-21
10869362-1	2000	In the present work, by titrating cytochrome c oxidase (COX) with the specific inhibitor KCN, the flux control coefficient and the metabolic reserve capacity of COX have been determined in human saponin-permeabilized muscle fibers.	Potassium Cyanide	89-92	cytochrome c oxidase subunit 8A	Homo sapiens	56-59
10869362-1	2000	In the present work, by titrating cytochrome c oxidase (COX) with the specific inhibitor KCN, the flux control coefficient and the metabolic reserve capacity of COX have been determined in human saponin-permeabilized muscle fibers.	Potassium Cyanide	89-92	cytochrome c oxidase subunit 8A	Homo sapiens	161-164
10683583-2	2000	Antibodies against lipocortin-1 identified activated and phagocytic cells that were abundant in a slice after the plating of a culture: cells of the intermediate form at the later time-points of culturing, resting ramified microglia beginning from the seventh day of culturing, as well as activated and phagocytic cells that appeared in the slice after experimental toxic hypoxia induced by potassium cyanide treatment.	Potassium Cyanide	391-408	annexin A1	Homo sapiens	19-31
10723097-5	2000	Brief exposure of cells to potassium cyanide to simulate chemical hypoxia induced 9-fold and 7-fold transient increases in c-fos and zif268 expression, respectively, but did not affect c-myc or nur77 expression.	Potassium Cyanide	27-44	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	123-128
10723097-5	2000	Brief exposure of cells to potassium cyanide to simulate chemical hypoxia induced 9-fold and 7-fold transient increases in c-fos and zif268 expression, respectively, but did not affect c-myc or nur77 expression.	Potassium Cyanide	27-44	early growth response 1	Rattus norvegicus	133-139
10770954-7	2000	In contrast, both of these compounds are oxidized at C-7 by a xanthine oxidase variant form, which is inactivated by KCN, but is insensitive to allopurinol.	Potassium Cyanide	117-120	xanthine oxidase	Danio rerio	62-78
10805448-7	2000	Anaerobic conditions or addition of potassium cyanide caused a decrease in PSII yield, providing evidence for operation of the ascorbate-dependent Mehler-peroxidase reaction.	Potassium Cyanide	36-53	peroxidase 1	Zea mays	154-164
10374822-7	1999	In the glucose-free DMEM, selective PKC isozyme inhibitor Go 6976 at 10 nM completely inhibited KCN-induced LDH release and at higher concentrations (1 microM) inhibited the basal levels of LDH release.	Potassium Cyanide	96-99	protein kinase C, gamma	Rattus norvegicus	36-39
10440270-1	1999	PURPOSE: To investigate the neuroprotective effects of brain-derived neurotrophic factor (BDNF) against potassium cyanide (KCN)-induced retinal damage.	Potassium Cyanide	104-121	brain-derived neurotrophic factor	Rattus norvegicus	55-88
10440270-1	1999	PURPOSE: To investigate the neuroprotective effects of brain-derived neurotrophic factor (BDNF) against potassium cyanide (KCN)-induced retinal damage.	Potassium Cyanide	104-121	brain-derived neurotrophic factor	Rattus norvegicus	90-94
10440270-1	1999	PURPOSE: To investigate the neuroprotective effects of brain-derived neurotrophic factor (BDNF) against potassium cyanide (KCN)-induced retinal damage.	Potassium Cyanide	123-126	brain-derived neurotrophic factor	Rattus norvegicus	55-88
10440270-1	1999	PURPOSE: To investigate the neuroprotective effects of brain-derived neurotrophic factor (BDNF) against potassium cyanide (KCN)-induced retinal damage.	Potassium Cyanide	123-126	brain-derived neurotrophic factor	Rattus norvegicus	90-94
10440270-11	1999	When eyes injected with either phosphate-buffered saline (PBS) or BDNF were subjected to treatment with KCN, the number of INL cells was 186 +/- 5 in the PBS-treated controls and 253 +/- 8 in eyes treated with BDNF.	Potassium Cyanide	104-107	brain derived neurotrophic factor	Homo sapiens	66-70
10440270-11	1999	When eyes injected with either phosphate-buffered saline (PBS) or BDNF were subjected to treatment with KCN, the number of INL cells was 186 +/- 5 in the PBS-treated controls and 253 +/- 8 in eyes treated with BDNF.	Potassium Cyanide	104-107	brain derived neurotrophic factor	Homo sapiens	210-214
10440270-12	1999	Also, BDNF increased the number of calretinin-positive cells in the INL and reduced the KCN-induced elevation of intravitreal glutamate levels.	Potassium Cyanide	88-91	brain-derived neurotrophic factor	Rattus norvegicus	6-10
10440270-13	1999	CONCLUSIONS: BDNF injected intravitreally reaches the retina and attenuates the INL cell death caused by KCN-induced metabolic insult.	Potassium Cyanide	105-108	brain-derived neurotrophic factor	Rattus norvegicus	13-17
10215936-2	1999	Hypoxia and metabolic poisoning with KCN rapidly inhibited INa by reducing the number of Na+ channels available for opening during depolarization.	Potassium Cyanide	37-40	internexin neuronal intermediate filament protein, alpha	Mus musculus	59-62
10349873-3	1999	In adult rats, the inhibition of mitochondrial ATP production with KCN (5 mM), oligomycin (10 microM), or rotenone (10 microM) reduced the incorporation of [3H]palmitate into fatty acyl-CoA and glycerolipids by 50-60%, whereas the labeling of PLP was unaltered.	Potassium Cyanide	67-70	proteolipid protein 1	Rattus norvegicus	243-246
10374822-11	1999	Although only the levels in the nuclear PKC-gamma but not other PKC isozymes were increased significantly following KCN, the levels of cPKC-alpha and -gamma in the membrane mainly- and those and PKC-epsilon in the nucleus-were increased when KCN was combined with TPA.	Potassium Cyanide	116-119	protein kinase C, gamma	Rattus norvegicus	40-49
10374822-11	1999	Although only the levels in the nuclear PKC-gamma but not other PKC isozymes were increased significantly following KCN, the levels of cPKC-alpha and -gamma in the membrane mainly- and those and PKC-epsilon in the nucleus-were increased when KCN was combined with TPA.	Potassium Cyanide	116-119	protein kinase C, gamma	Rattus norvegicus	40-43
10374822-13	1999	Taking the results together, differential activation/translocation of PKC isozymes by KCN and TPA is important in the regulation of chemical hypoxia-induced cell injury in PC12 cells.	Potassium Cyanide	86-89	protein kinase C, gamma	Rattus norvegicus	70-73
9988735-6	1999	Flow cytometric analysis showed that mitochondrial PHGPx suppressed the generation of hydroperoxide, the loss of mitochondrial membrane potential, and the loss of plasma membrane integrity that are induced by KCN.	Potassium Cyanide	209-212	glutathione peroxidase 4	Rattus norvegicus	51-56
10334200-11	1999	Mucosal esophageal flux of MNAN and dimethyl-NAm was reduced by >90% on enzymic removal of the stratum corneum, was unaffected by 0.1 mM verapamil and was inhibited 67-94% by 1.0 mM KCN and 82-93% by 0.23% ethanol.	Potassium Cyanide	185-188	SH3 and cysteine rich domain 3	Homo sapiens	45-48
10197422-5	1999	The cell-free extract of Clostridium sporogenes had debrominating activity in the presence of both FMN and NADH (or NADPH), and this activity was inhibited by sodium arsenite and potassium cyanide.	Potassium Cyanide	179-196	2,4-dienoyl-CoA reductase 1	Homo sapiens	116-121
9825399-9	1998	High post-dialytic rebounds (and low Kcn values) were associated with erythropoietin use (p < 0.05) and occurrence of end-dialytic hypotension (p < 0.02).	Potassium Cyanide	37-40	erythropoietin	Homo sapiens	70-84
9803413-10	1998	The haem ligands NaN3 and KCN caused a 50% inhibition of catalase activity at 9 and 19 microM, respectively.	Potassium Cyanide	26-29	catalase	Bos taurus	57-65
9724695-2	1998	The respiratory inhibitors antimycin A and KCN also induced Aox transcript accumulation and resistance to TMV but did not induce PR-1 accumulation.	Potassium Cyanide	44-47	acyl-CoA oxidase 1	Homo sapiens	61-64
9826433-2	1998	Incubation of MPTP with mitochondrial fraction gave exclusively 1-methyl-4-phenylpyridinium (MPP+); this reaction was inhibited by deprenyl, a monoamine oxidase (MAO)-B inhibitor, and KCN.	Potassium Cyanide	184-187	monoamine oxidase B	Mus musculus	143-168
9556634-5	1998	In fact, an increase of KCN-dependent O2 consumption accompanied the expression of Bax.	Potassium Cyanide	24-27	BCL2 associated X, apoptosis regulator	Homo sapiens	83-86
9536016-4	1998	Using selective enzyme inhibitors, it was shown that both protein kinase C and phospholipase A2 are involved in KCN-stimulated generation of NO and ROS.	Potassium Cyanide	112-115	phospholipase A2 group IB	Homo sapiens	79-95
11672106-2	1998	The methodology involves the use of 4,4-disubstituted-N-Boc beta-lactams as acylating agents, which upon coupling with amino acid esters, promoted by potassium cyanide, give rise to dipeptides with no appreciable racemization.	Potassium Cyanide	150-167	BOC cell adhesion associated, oncogene regulated	Homo sapiens	56-59
9536016-7	1998	Pretreatment with NS398 (COX-2 inhibitor) significantly decreased ROS generation indicating the involvement of COX-2 in KCN-induced oxidant generation.	Potassium Cyanide	120-123	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	25-30
9536016-7	1998	Pretreatment with NS398 (COX-2 inhibitor) significantly decreased ROS generation indicating the involvement of COX-2 in KCN-induced oxidant generation.	Potassium Cyanide	120-123	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	111-116
9536016-11	1998	Pretreatment with inhibitors of protein kinase C, phospholipase A2 or COX, LOX, COX-2 partially blocked KCN-induced formation of thiobarbituric acid reactive substance, whereas coincubation of L-NAME with the inhibitors decreased lipid peroxidation by 60 to 90%.	Potassium Cyanide	104-107	phospholipase A2 group IB	Homo sapiens	50-66
9536016-11	1998	Pretreatment with inhibitors of protein kinase C, phospholipase A2 or COX, LOX, COX-2 partially blocked KCN-induced formation of thiobarbituric acid reactive substance, whereas coincubation of L-NAME with the inhibitors decreased lipid peroxidation by 60 to 90%.	Potassium Cyanide	104-107	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	80-85
9489022-5	1998	Aggravated photodamage was observed upon illumination of barley leaves infiltrated with KCN, which inhibits Cu,Zn-superoxide dismutase and ascorbate peroxidase.	Potassium Cyanide	88-91	prx7	Hordeum vulgare	149-159
9602861-8	1998	In contrast, DNA fragments induced by Triton X-100 and KCN peaked below 0.5 Mbp, implicating activation of DNA-degrading enzymes.	Potassium Cyanide	55-58	myelin basic protein	Homo sapiens	76-79
33863099-2	1998	Mitochondrial and peroxisomal isoforms of SOD could be distinguished in nondenaturing polyacrylamide gels by their differential sensitivities to KCN and/or H2 O2 .	Potassium Cyanide	145-148	superoxide dismutase [Mn], mitochondrial	Cucumis sativus	42-45
9462835-6	1998	In addition, the NADH oxidase activity of the NDI1-overexpressed membranes was also inhibited by KCN as well as the control membranes.	Potassium Cyanide	97-100	NADH-ubiquinone reductase (H(+)-translocating) NDI1	Saccharomyces cerevisiae S288C	46-50
9214581-6	1997	The decrease of glutathione was prevented by added catalase, or by addition of NaN3 or KCN which inhibits myeloperoxidase (MPO).	Potassium Cyanide	87-90	myeloperoxidase	Rattus norvegicus	106-121
9316090-1	1997	L-2,4-Diamino[4-11C]butyric acid (DAB) was synthesized by an enzyme catalysed carrier added (0.1 micromol KCN) reaction of hydrogen [11C]cyanide with O-acetyl-L-serine followed by reduction.	Potassium Cyanide	106-109	immunoglobulin kappa variable 3-15	Homo sapiens	0-3
9105692-13	1997	KCN, DNP and FCCP inhibited [Ca2+]i responses to tolbutamide to a much greater extent than those to A-4166.	Potassium Cyanide	0-3	carbonic anhydrase 2	Rattus norvegicus	29-32
9209397-5	1997	The anti-apoptotic proteins Bcl-2 and Bcl-xL effectively inhibit KCN-induced cell death which is characterized by necrotic features including apparently intact chromatin, remarkable mitochondrial swelling with loss of crista structure and loss of plasma membrane integrity.	Potassium Cyanide	65-68	BCL2 apoptosis regulator	Homo sapiens	28-33
9209397-5	1997	The anti-apoptotic proteins Bcl-2 and Bcl-xL effectively inhibit KCN-induced cell death which is characterized by necrotic features including apparently intact chromatin, remarkable mitochondrial swelling with loss of crista structure and loss of plasma membrane integrity.	Potassium Cyanide	65-68	BCL2 like 1	Homo sapiens	38-44
8897823-2	1996	In this study, we have quantitated HIF-1 DNA-binding activity and protein levels of the HIF-1 alpha and HIF-1 beta subunits in human HeLa cells exposed to O2 concentrations ranging from 0 to 20% in the absence or presence of 1 mM KCN to inhibit oxidative phosphorylation and cellular O2 consumption.	Potassium Cyanide	230-233	hypoxia inducible factor 1 subunit alpha	Homo sapiens	88-99
9214581-6	1997	The decrease of glutathione was prevented by added catalase, or by addition of NaN3 or KCN which inhibits myeloperoxidase (MPO).	Potassium Cyanide	87-90	myeloperoxidase	Rattus norvegicus	123-126
8752110-10	1996	Exposure of cells to 0.1 mM KCN produced a rapid generation of oxidants that was blocked approximately 50% by ascorbate or catalase.	Potassium Cyanide	28-31	catalase	Rattus norvegicus	123-131
8619232-3	1996	However, the cytotoxicity and intracellular accumulation of As(V) were dramatically enhanced, equalling those of As(III) when cells were grown in phosphate-free RPMI medium, As(V) uptake was dose-dependently inhibited by phosphate, mersalyl acid (a membrane sulfhydryl agent), and energy poisons, such as sodium azide and potassium cyanide.	Potassium Cyanide	322-339	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	60-65
8649764-5	1996	Induction of necrotic cell death by KCN also induces activation of ICE(-like) proteases but not of CPP32/Yama(-like) proteases, and Bcl-2 and Bcl-xL inhibit the activation and the cell death, suggesting that the functional site of Bcl-2 and Bcl-xL is also upstream of ICE(-like) proteases in at least some forms of necrosis.	Potassium Cyanide	36-39	carboxylesterase 2	Homo sapiens	67-70
8649764-5	1996	Induction of necrotic cell death by KCN also induces activation of ICE(-like) proteases but not of CPP32/Yama(-like) proteases, and Bcl-2 and Bcl-xL inhibit the activation and the cell death, suggesting that the functional site of Bcl-2 and Bcl-xL is also upstream of ICE(-like) proteases in at least some forms of necrosis.	Potassium Cyanide	36-39	BCL2 apoptosis regulator	Homo sapiens	132-137
8649764-5	1996	Induction of necrotic cell death by KCN also induces activation of ICE(-like) proteases but not of CPP32/Yama(-like) proteases, and Bcl-2 and Bcl-xL inhibit the activation and the cell death, suggesting that the functional site of Bcl-2 and Bcl-xL is also upstream of ICE(-like) proteases in at least some forms of necrosis.	Potassium Cyanide	36-39	BCL2 like 1	Homo sapiens	142-148
8649764-5	1996	Induction of necrotic cell death by KCN also induces activation of ICE(-like) proteases but not of CPP32/Yama(-like) proteases, and Bcl-2 and Bcl-xL inhibit the activation and the cell death, suggesting that the functional site of Bcl-2 and Bcl-xL is also upstream of ICE(-like) proteases in at least some forms of necrosis.	Potassium Cyanide	36-39	BCL2 apoptosis regulator	Homo sapiens	231-236
8649764-5	1996	Induction of necrotic cell death by KCN also induces activation of ICE(-like) proteases but not of CPP32/Yama(-like) proteases, and Bcl-2 and Bcl-xL inhibit the activation and the cell death, suggesting that the functional site of Bcl-2 and Bcl-xL is also upstream of ICE(-like) proteases in at least some forms of necrosis.	Potassium Cyanide	36-39	BCL2 like 1	Homo sapiens	241-247
8649764-5	1996	Induction of necrotic cell death by KCN also induces activation of ICE(-like) proteases but not of CPP32/Yama(-like) proteases, and Bcl-2 and Bcl-xL inhibit the activation and the cell death, suggesting that the functional site of Bcl-2 and Bcl-xL is also upstream of ICE(-like) proteases in at least some forms of necrosis.	Potassium Cyanide	36-39	carboxylesterase 2	Homo sapiens	268-271
8613912-2	1996	KCN produced a concentration-dependent (25-200 microM) generation of intracellular oxidant species that was blocked by N-methyl-D-aspartate receptor antagonists (MK-801 or AP5) or by removal of extracellular Ca++ from the incubation medium.	Potassium Cyanide	0-3	adaptor related protein complex 5 subunit beta 1	Homo sapiens	172-175
8613912-6	1996	Combination of SOD with hemoglobin or L-NAME provided additional attenuation of the fluorescence and it was concluded that both NO and ROS are generated concurrently after KCN.	Potassium Cyanide	172-175	superoxide dismutase 1	Homo sapiens	15-18
8613912-9	1996	Treatment with a combination of SOD/catalase and L-NAME blocked the KCN-induced lipid peroxidation.	Potassium Cyanide	68-71	superoxide dismutase 1	Homo sapiens	32-35
8613912-9	1996	Treatment with a combination of SOD/catalase and L-NAME blocked the KCN-induced lipid peroxidation.	Potassium Cyanide	68-71	catalase	Homo sapiens	36-44
8696257-9	1996	Treatment of cultured lens epithelial cells or rabbit lenses with 3-aminotriazole or potassium cyanide, inhibitors of catalase, reduced or abolished the histochemical reaction product.	Potassium Cyanide	85-102	catalase	Oryctolagus cuniculus	118-126
12226312-3	1996	This led to a large increase in the capacity for AOX respiration, defined as the amount of salicylhydroxamic acid-sensitive O2 uptake by cells in the presence of potassium cyanide.	Potassium Cyanide	162-179	ubiquinol oxidase 1, mitochondrial	Nicotiana tabacum	49-52
8645214-6	1996	The catalase activity was not inhibited by 3-amino-1,2,4-triazole but by KCN and NaN3 (apparent Ki values 19.3 +/- 0.84 and 20.2 +/- 0.95 microM respectively).	Potassium Cyanide	73-76	pfam00199	Synechococcus elongatus PCC 7942	4-12
8619232-3	1996	However, the cytotoxicity and intracellular accumulation of As(V) were dramatically enhanced, equalling those of As(III) when cells were grown in phosphate-free RPMI medium, As(V) uptake was dose-dependently inhibited by phosphate, mersalyl acid (a membrane sulfhydryl agent), and energy poisons, such as sodium azide and potassium cyanide.	Potassium Cyanide	322-339	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	174-179
7729487-4	1995	In all cases, this was accounted for predominantly by CuZn SOD, assessed by potassium cyanide inhibition.	Potassium Cyanide	76-93	superoxide dismutase 1	Homo sapiens	59-62
7881866-6	1994	Bovine kidney rhodanese (0.40 mg/ml protein) was reacted with 4 mM KCN and SCN- production determined spectrophotometrically following the method of Westley (1981).	Potassium Cyanide	67-70	thiosulfate sulfurtransferase	Bos taurus	14-23
7796171-1	1995	The effect of potassium cyanide-induced chemical hypoxia on protein kinase C (PKC) translocation and cell injury was studied in differentiated PC12 cells.	Potassium Cyanide	14-31	protein kinase C, gamma	Rattus norvegicus	60-76
7796171-1	1995	The effect of potassium cyanide-induced chemical hypoxia on protein kinase C (PKC) translocation and cell injury was studied in differentiated PC12 cells.	Potassium Cyanide	14-31	protein kinase C, gamma	Rattus norvegicus	78-81
7796171-2	1995	The cellular distribution of PKC in control cells and cells exposed to 100 microM and 1 mM KCN for 30 min.	Potassium Cyanide	91-94	protein kinase C, gamma	Rattus norvegicus	29-32
7796171-9	1995	PKC activation plays a role in hypoxic damage, since PKC down-regulation (by overnight exposure to PMA) or inhibition (with chelerythrine or staurosporine) conferred protection against KCN-induced cytotoxicity.	Potassium Cyanide	185-188	protein kinase C, gamma	Rattus norvegicus	0-3
7796171-9	1995	PKC activation plays a role in hypoxic damage, since PKC down-regulation (by overnight exposure to PMA) or inhibition (with chelerythrine or staurosporine) conferred protection against KCN-induced cytotoxicity.	Potassium Cyanide	185-188	protein kinase C, gamma	Rattus norvegicus	53-56
7706272-5	1995	Stoichiometric equivalent increases of AdK-catalyzed phosphotransfer and anaerobic ATP production also occurred up to more than 20-fold when oxidative phosphorylation was impaired by either O2 deprivation or treatment with KCN or p-(trifluoromethoxy)-phenylhydrazone.	Potassium Cyanide	223-226	adenosine kinase	Rattus norvegicus	39-42
12228374-5	1995	From experiments with KCN and salicylhydroxamic acid, it was estimated that the capacity of the cytochrome pathway was at least 100 nmol O2 mg-1 protein min-1 and the capacity of the alternative oxidase was at least 50 nmol O2 mg-1 protein min-1.	Potassium Cyanide	22-25	uncharacterized protein	Chlamydomonas reinhardtii	153-158
12228374-5	1995	From experiments with KCN and salicylhydroxamic acid, it was estimated that the capacity of the cytochrome pathway was at least 100 nmol O2 mg-1 protein min-1 and the capacity of the alternative oxidase was at least 50 nmol O2 mg-1 protein min-1.	Potassium Cyanide	22-25	uncharacterized protein	Chlamydomonas reinhardtii	240-245
7770068-6	1995	Besides the nuclear delta 5 desaturase has an optimal pH of 7.6 and is inhibited by 1 or 10 mM KCN.	Potassium Cyanide	95-98	fatty acid desaturase 1	Rattus norvegicus	20-38
7813471-7	1994	This was achieved by measuring the effects of KCN (or malonate or N,N,N",N"-tetramethyl-p-phenylenediamine) on system flux when intermediates were allowed to relax and on local flux when intermediates were held constant.	Potassium Cyanide	46-49	neurogenin 3	Rattus norvegicus	158-163
7881866-7	1994	Preincubating rhodanese with 20 or 100 ng of purified PKC (alpha, beta, gamma isozymes) for 5 min before initiating the reaction with 4 mM KCN as the substrate increased SCN- production by 17 or 40%, respectively, over the control (P < 0.05).	Potassium Cyanide	139-142	thiosulfate sulfurtransferase	Bos taurus	14-23
7881182-5	1994	The purified CMP-Neu5Ac hydroxylase is activated by FeSO4 and inhibited by iron-binding reagents such as o-phenanthroline, KCN, Tiron and ferrozine.	Potassium Cyanide	123-126	cytidine monophospho-N-acetylneuraminic acid hydroxylase	Sus scrofa	13-35
8086173-5	1994	MnSOD activity was measured by inhibition of cytochrome c reduction in the presence of 1 mM KCN, MnSOD protein content was measured on immunoblots, and MnSOD mRNA was quantified on slot blot autoradiograms.	Potassium Cyanide	92-95	SOD-2	Oryctolagus cuniculus	0-5
8075245-5	1994	Superoxide dismutase as well as KCN suppressed the radical production, thus being suggestive of the generation of superoxide radicals in the bc1 complex, while the mechanism of O2- production is the same as was suggested for isolated mitochondria.	Potassium Cyanide	32-35	brain cytoplasmic RNA 1	Rattus norvegicus	141-144
12232282-7	1994	The inhibition of respiration by KCN or antimycin A was more in GCP than that in MCP.	Potassium Cyanide	33-36	CD46 molecule	Homo sapiens	81-84
8209387-7	1994	In poisoned heart mitochondria (1 mM KCN) simultaneous estimations of ATP synthesis and COx activity in a closed oxygraph chamber showed a recovery of only 6% of both activities upon the addition of 12 mM pyruvate.	Potassium Cyanide	37-40	coproporphyrinogen oxidase	Rattus norvegicus	88-91
7910563-6	1994	Calcein accumulation was also increased in Pgp-expressing cells by the addition of the Pgp substrate vincristine and the metabolic inhibitor potassium cyanide, KCN.	Potassium Cyanide	141-158	ATP binding cassette subfamily B member 1	Homo sapiens	43-46
7910563-6	1994	Calcein accumulation was also increased in Pgp-expressing cells by the addition of the Pgp substrate vincristine and the metabolic inhibitor potassium cyanide, KCN.	Potassium Cyanide	160-163	ATP binding cassette subfamily B member 1	Homo sapiens	43-46
8126749-1	1994	Murine carrier erythrocytes containing bovine rhodanese and sodium thiosulfate are being explored as a new approach to antagonize the lethal effects of potassium cyanide in mice.	Potassium Cyanide	152-169	thiosulfate sulfurtransferase	Bos taurus	46-55
7925244-7	1994	Treatment with EDTA produces 1-2 additional, slightly higher pI isoforms, whereas treatment with KCN generates a number of higher pI components, reaching pI values as high as pH 7, with nearly complete disappearance of the three major SOD isoforms.	Potassium Cyanide	97-100	superoxide dismutase 1	Homo sapiens	235-238
8303757-6	1994	RESULTS: 2-Deoxyglucose/potassium cyanide incubation resulted in dose-dependent, regionally selective neuronal injury in CA1 and the dentate hilus, which began slowly after 2 to 6 hours of recovery.	Potassium Cyanide	24-41	carbonic anhydrase 1	Rattus norvegicus	121-124
8122272-2	1994	This prompted a study of the effects of KCN on phospholipase A2 (PLA2), an enzyme which catalyzes breakdown of membrane phospholipids.	Potassium Cyanide	40-43	phospholipase A2 group IB	Rattus norvegicus	47-63
8122272-2	1994	This prompted a study of the effects of KCN on phospholipase A2 (PLA2), an enzyme which catalyzes breakdown of membrane phospholipids.	Potassium Cyanide	40-43	phospholipase A2 group IB	Rattus norvegicus	65-69
8122272-7	1994	The PLA2 inhibitors dibucaine (50 microM) and mepacrine (50 microM) inhibited KCN-mediated [3H]AA release.	Potassium Cyanide	78-81	phospholipase A2 group IB	Rattus norvegicus	4-8
8387330-7	1993	Conversely, in ANP-treated SHRs, CC was significantly increased compared with untreated SHRs under basal conditions (p < 0.03) and after potassium cyanide poisoning (p < 0.02).	Potassium Cyanide	140-157	natriuretic peptide A	Rattus norvegicus	15-18
8122272-9	1994	These data indicate that in PC12 cells KCN activates a Ca(2+)- and pH-dependent PLA2 which may contribute to cyanide-induced cell damage.	Potassium Cyanide	39-42	phospholipase A2 group IB	Rattus norvegicus	80-84
8136492-5	1993	SOD activity from H37Rv extract was not affected by 1 mM KCN or by 5 mM H2O2 and was only 20% inhibited by 10 mM NaN3, suggesting that it is a Mn-containing enzyme.	Potassium Cyanide	57-60	superoxide dismutase	Mycobacterium tuberculosis H37Rv	0-3
8139769-3	1994	Treatment with KCN, an in vitro model of hypoxia decreased ATP and elevated [Ca2+]i and PDHa.	Potassium Cyanide	15-18	pyruvate dehydrogenase E1 subunit alpha 1	Homo sapiens	88-92
8139769-4	1994	Furthermore, in the presence of KCN, PDHa became more sensitive to K+ depolarization as indicated by larger changes in PDHa than in [Ca2+]i.	Potassium Cyanide	32-35	pyruvate dehydrogenase E1 subunit alpha 1	Homo sapiens	37-41
8139769-4	1994	Furthermore, in the presence of KCN, PDHa became more sensitive to K+ depolarization as indicated by larger changes in PDHa than in [Ca2+]i.	Potassium Cyanide	32-35	pyruvate dehydrogenase E1 subunit alpha 1	Homo sapiens	119-123
1322110-9	1992	Addition of catalase inhibitor KCN prior to H2O2 treatment increased the yield of cross-linking over the level observed with H2O2 treatment alone.	Potassium Cyanide	31-34	catalase	Homo sapiens	12-20
8461316-1	1993	A concentration-dependent inactivation of 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase was found on preincubation of rat liver microsomal preparations with H2O2 and at lower concentrations in the presence of KCN which inhibited the contaminating catalase.	Potassium Cyanide	215-218	3-hydroxy-3-methylglutaryl-CoA reductase	Rattus norvegicus	42-93
1326560-5	1992	The concentrated cytochrome b558 showed an EPR signal at a g value of 3.26 with a bandwidth of 100 G at 10 K. Addition of 2 mM KCN had no effect on the low spin signal at g = 3.26 but caused disappearance of a minor high spin signal.	Potassium Cyanide	127-130	cytochrome b	Sus scrofa	17-29
1786300-4	1991	Perifusion of caput tubules with 0.1 mM dinitrophenol or potassium cyanide or 100 micrograms/ml cyclohexamide significantly reduced proluminal 3H-androgen movement, but tubules perifused with control medium would not support antigrade 3H-androgen movement in the absence of native lumen fluids which contain androgen-binding protein.	Potassium Cyanide	57-74	sex hormone binding globulin	Rattus norvegicus	308-332
1537807-6	1992	High concentrations of potassium cyanide inactivated histidase in the absence of its substrate or histidinol phosphate, suggesting that, as in other histidases, dehydroalanine plays an important role in catalysis.	Potassium Cyanide	23-40	histidine ammonia-lyase	Homo sapiens	53-62
1662908-23	1991	Intracellular ATP depletion, using KCN or replacement of glucose by a nonmetabolizable glucose analogue, reduced pHi recovery by 70-75% relative to control values.	Potassium Cyanide	35-38	glucose-6-phosphate isomerase	Homo sapiens	113-116
1314493-5	1992	Also, metabolic inhibition by absence of substrate, 10(-4) M KCN, or 5 x 10(-4) M iodoacetic acid inhibited amiloride-insensitive pHi recovery.	Potassium Cyanide	61-64	glucose-6-phosphate isomerase	Rattus norvegicus	130-133
1317456-6	1992	Pre-exposure of the tubules to 30 mM fructose, 0.5 mM iodoacetate and 1 mM KCN (to deplete intracellular ATP) prevented a pHi recovery in Na(+)-free media; readdition of Na+ led to an immediate pHi recovery.	Potassium Cyanide	75-78	glucose-6-phosphate isomerase	Rattus norvegicus	122-125
1317456-6	1992	Pre-exposure of the tubules to 30 mM fructose, 0.5 mM iodoacetate and 1 mM KCN (to deplete intracellular ATP) prevented a pHi recovery in Na(+)-free media; readdition of Na+ led to an immediate pHi recovery.	Potassium Cyanide	75-78	glucose-6-phosphate isomerase	Rattus norvegicus	194-197
1600191-3	1992	Phenoloxidase inhibitors such as potassium cyanide and sodium fluoride inhibited the enzyme activity drastically, but phenylthiourea showed marginal inhibition only.	Potassium Cyanide	33-50	Phox	Drosophila melanogaster	0-13
2009301-6	1991	(b) The delta 9-desaturase, present in microsomes from rats fed a fat-free diet, was totally inhibited by 4 mM KCN; beta-ketopalmitoyl-CoA or malonyl-CoA stimulated the reoxidation rate of cytochrome b5 but this increase was also inhibited by 4 mM KCN.	Potassium Cyanide	111-114	cytochrome b5 type A	Rattus norvegicus	189-202
2043677-2	1991	Incubation of BMAA with L-AAO in the presence of semicarbazide led to the formation of a semicarbazone, indicating intermediate iminium ion formation; when potassium cyanide (5 mM) was added, semicarbazone formation was blocked.	Potassium Cyanide	156-173	interleukin 4 induced 1	Homo sapiens	24-29
1707675-4	1991	S1 nuclease analysis illustrated that pretreatment of Hep G2 cells with KCN, a copper specific chelator and uptake inhibitor, suppressed 5-azacytidine- and copper-inducible MT-IG gene expression.	Potassium Cyanide	72-75	DNL-type zinc finger	Homo sapiens	54-57
1707675-4	1991	S1 nuclease analysis illustrated that pretreatment of Hep G2 cells with KCN, a copper specific chelator and uptake inhibitor, suppressed 5-azacytidine- and copper-inducible MT-IG gene expression.	Potassium Cyanide	72-75	metallothionein 1G	Homo sapiens	173-178
2249624-6	1990	Binding studies at 15 C in the presence of potassium cyanide revealed that this effect was associated with an increase in insulin receptor affinity.	Potassium Cyanide	43-60	insulin receptor	Rattus norvegicus	122-138
1899571-3	1991	Loss of cell viability and phospholipase A2 activity measured by arachidonic acid release increased in parallel during metabolic inhibition with KCN and iodoacetate (chemical hypoxia).	Potassium Cyanide	145-148	phospholipase A2 group IB	Rattus norvegicus	27-43
2145772-7	1990	Dose-dependent reductions in ATP levels and in the rate of pHi recovery were obtained in the presence of KCN (50% inhibition, 10(-4) M).	Potassium Cyanide	105-108	glucose-6-phosphate isomerase	Homo sapiens	59-62
2256111-3	1990	KCN (1-10 mM) rapidly decreased intracellular pH (pHi) of cultured pheochromocytoma (PC12) cells as indicated by the pH-sensitive fluorescent dye 2",7-bis(carboxyethyl)-5(6)-carboxyfluorescein.	Potassium Cyanide	0-3	glucose-6-phosphate isomerase	Rattus norvegicus	46-48
2256111-3	1990	KCN (1-10 mM) rapidly decreased intracellular pH (pHi) of cultured pheochromocytoma (PC12) cells as indicated by the pH-sensitive fluorescent dye 2",7-bis(carboxyethyl)-5(6)-carboxyfluorescein.	Potassium Cyanide	0-3	glucose-6-phosphate isomerase	Rattus norvegicus	50-53
2256111-3	1990	KCN (1-10 mM) rapidly decreased intracellular pH (pHi) of cultured pheochromocytoma (PC12) cells as indicated by the pH-sensitive fluorescent dye 2",7-bis(carboxyethyl)-5(6)-carboxyfluorescein.	Potassium Cyanide	0-3	glucose-6-phosphate isomerase	Rattus norvegicus	50-52
2171158-4	1990	The basis for this age-related difference in in vivo toxicity was examined by studying biotransformation of KCN to thiocyanate by liver and brain rhodanese (RHO), as well as activity of liver and brain cytochrome oxidase (C-OX), inhibition of C-OX by KCN, and activity of beta-mercaptopyruvate transsulfurase (MT).	Potassium Cyanide	108-111	thiosulfate sulfurtransferase, mitochondrial	Mus musculus	146-155
2470761-4	1989	In addition, a 2-3-fold increase in the binding of monoclonal antibody 2C6, which recognizes a component of the alpha 2M receptor, was found in cells treated at 37 degrees C with insulin and then KCN to inhibit receptor endocytosis.	Potassium Cyanide	196-199	alpha-2-macroglobulin	Homo sapiens	112-120
34514925-4	2021	We asked how many of the five sod genes are actually making active SOD enzymes in C. elegans through usage of in-gel SOD activity analysis and by using KCN as a selective inhibitor against Cu-ZnSOD enzyme(s).	Potassium Cyanide	152-155	Superoxide dismutase [Mn] 1, mitochondrial	Caenorhabditis elegans	30-33
34514925-4	2021	We asked how many of the five sod genes are actually making active SOD enzymes in C. elegans through usage of in-gel SOD activity analysis and by using KCN as a selective inhibitor against Cu-ZnSOD enzyme(s).	Potassium Cyanide	152-155	Superoxide dismutase [Mn] 1, mitochondrial	Caenorhabditis elegans	67-70
2760616-2	1989	The cytosolic and particulate isoenzymes of SOD were differentiated by the inclusion of potassium cyanide which selectively inhibits cytosolic copper/zinc-dependent SOD activity.	Potassium Cyanide	88-105	superoxide dismutase 1	Homo sapiens	44-47
2760616-2	1989	The cytosolic and particulate isoenzymes of SOD were differentiated by the inclusion of potassium cyanide which selectively inhibits cytosolic copper/zinc-dependent SOD activity.	Potassium Cyanide	88-105	superoxide dismutase 1	Homo sapiens	165-168
34268805-6	2021	Indeed, potassium cyanide abruptly stops oxygen uptake, indicating that the cytochrome c pathway is likely to be engaged.	Potassium Cyanide	8-25	cytochrome c	Solanum lycopersicum	76-88
2619068-2	1989	The specificity is based on the selective oxidation of PLP to 4-pyridoxic acid 5"-phosphate with potassium cyanide.	Potassium Cyanide	97-114	pyridoxal phosphatase	Homo sapiens	55-58
24201664-2	1989	Addition of 0.5-5 mM KCN to these samples resulted in a large increase in the slow electrochromic rise originating from the electrogenic activity of the cytochrome b/f complex.	Potassium Cyanide	21-24	cytochrome b	Nicotiana tabacum	153-165
2758038-5	1989	Mitochondrial inhibitors (KCN and carbonylcyanide p-trifluoromethoxyphenylhydrazone) preferentially suppressed the gastrin response.	Potassium Cyanide	26-29	gastrin	Rattus norvegicus	115-122
2734799-5	1989	Thirty minutes after KCN, brain catalase (CA), glutathione peroxidase (GPX) and glutathione reductase (GR) activities were significantly reduced (percent inhibition compared to control: CA 44%, GPX 30%, and GR 41%).	Potassium Cyanide	21-24	catalase	Mus musculus	32-40
2734799-5	1989	Thirty minutes after KCN, brain catalase (CA), glutathione peroxidase (GPX) and glutathione reductase (GR) activities were significantly reduced (percent inhibition compared to control: CA 44%, GPX 30%, and GR 41%).	Potassium Cyanide	21-24	catalase	Mus musculus	186-188
2552203-8	1989	Dicyclohexylcarbodiimide (DCCD), an inhibitor of a plasma membrane proton ATPase, and the depletion of cellular ATP induced by 2 mM potassium cyanide (KCN) also partially inhibited the rate of pHi recovery after cell acidification with a NH4Cl load.	Potassium Cyanide	132-149	glucose-6-phosphate isomerase	Rattus norvegicus	193-196
2548756-2	1989	FDP is able to inhibit Ca++ entry into the myocardial tissue with an IC50 value of 11.5 mM and in addition, it is bound by rat heart slices, the binding being activated by Zn and conditions of chemical hypoxia induced by KCN and iodoacetate.	Potassium Cyanide	221-224	fructose-bisphosphatase 1	Rattus norvegicus	0-3
2744000-3	1989	In the presence of KCNS and a high concentration of CaCl2 brain myosin and its rod precipitated in a form of segments displaying both bipolar and unipolar arrangement characteristic of the myosin filaments.	Potassium Cyanide	19-23	myosin heavy chain 14	Homo sapiens	64-70
2730881-2	1989	As compared with horseradish peroxidase (HRP), the values of the dissociation constant, Kd, of LPO-donor complexes were found to be 4-720-fold larger and were not greatly changed in the presence of KCN and by changes in pH in the range 4-9.	Potassium Cyanide	198-201	lactoperoxidase	Homo sapiens	95-98
2552203-8	1989	Dicyclohexylcarbodiimide (DCCD), an inhibitor of a plasma membrane proton ATPase, and the depletion of cellular ATP induced by 2 mM potassium cyanide (KCN) also partially inhibited the rate of pHi recovery after cell acidification with a NH4Cl load.	Potassium Cyanide	151-154	glucose-6-phosphate isomerase	Rattus norvegicus	193-196
2435723-4	1987	Brilliant cresyl blue and KCN inhibited both enzyme activation and hepatic cyclic GMP accumulation caused by agents that generate nitric oxide.	Potassium Cyanide	26-29	5'-nucleotidase, cytosolic II	Mus musculus	82-85
3421992-6	1988	The inhibition curves with clorgyline, deprenyl, semicarbazide and KCN, measuring the remaining activity towards 1 microM of benzylamine, indicated that in mitochondria 5% of the total activity is due to the presence of SSAO activity whereas in microsomes this activity represents about 20%.	Potassium Cyanide	67-70	amine oxidase, copper containing 3	Rattus norvegicus	220-224
2954159-2	1987	After the cells were incubated with insulin and/or GH, the recycling of IGF-II receptors was metabolically inhibited by treating the cells with KCN.	Potassium Cyanide	144-147	gonadotropin releasing hormone receptor	Rattus norvegicus	51-53
2954159-2	1987	After the cells were incubated with insulin and/or GH, the recycling of IGF-II receptors was metabolically inhibited by treating the cells with KCN.	Potassium Cyanide	144-147	insulin-like growth factor 2	Rattus norvegicus	72-78
3576625-1	1987	Pyridoxal 5"-phosphate (PLP), the active form of vitamin B6, readily forms complexes with a wide variety of potentially toxic substances, including cyanide (KCN), spermine (SPM), gentamicin (GM), and dopamine (DOP).	Potassium Cyanide	157-160	pyridoxal phosphatase	Homo sapiens	24-27
3576625-4	1987	For KCN, PLP increased the LD50 from 0.088 to 0.188 mmol/kg and extended the survival time at the highest dose employed from a median of 3 min to a median of 60 min.	Potassium Cyanide	4-7	pyridoxal phosphatase	Homo sapiens	9-12
2427122-1	1986	Cytochrome-c oxidase of bovine heart mitochondria was depleted of copper A by dialysis against 1 M KCN in the presence of dodecylmaltoside.	Potassium Cyanide	99-102	cytochrome c oxidase subunit 6A1, mitochondrial	Bos taurus	0-20
3026308-8	1986	Furthermore, by choosing a high pH for the assay medium, a 4-fold increase in sensitivity compared with the classical SOD assay, carried out at pH 7.8, was gained as well as a more precise resolution of Cu/Zn-SOD and Mn-SOD by 2 mM-KCN in samples with a high ratio of Mn-SOD to Cu/Zn-SOD, such as mitochondria.	Potassium Cyanide	232-235	superoxide dismutase 1	Rattus norvegicus	203-212
3026308-8	1986	Furthermore, by choosing a high pH for the assay medium, a 4-fold increase in sensitivity compared with the classical SOD assay, carried out at pH 7.8, was gained as well as a more precise resolution of Cu/Zn-SOD and Mn-SOD by 2 mM-KCN in samples with a high ratio of Mn-SOD to Cu/Zn-SOD, such as mitochondria.	Potassium Cyanide	232-235	superoxide dismutase 2	Rattus norvegicus	217-223
3026308-8	1986	Furthermore, by choosing a high pH for the assay medium, a 4-fold increase in sensitivity compared with the classical SOD assay, carried out at pH 7.8, was gained as well as a more precise resolution of Cu/Zn-SOD and Mn-SOD by 2 mM-KCN in samples with a high ratio of Mn-SOD to Cu/Zn-SOD, such as mitochondria.	Potassium Cyanide	232-235	superoxide dismutase 2	Rattus norvegicus	268-274
3026308-8	1986	Furthermore, by choosing a high pH for the assay medium, a 4-fold increase in sensitivity compared with the classical SOD assay, carried out at pH 7.8, was gained as well as a more precise resolution of Cu/Zn-SOD and Mn-SOD by 2 mM-KCN in samples with a high ratio of Mn-SOD to Cu/Zn-SOD, such as mitochondria.	Potassium Cyanide	232-235	superoxide dismutase 1	Rattus norvegicus	278-287
3015634-3	1986	Reproducible measurement of O2- formation required the presence of 0.2 mmol l-1 KCN to inhibit a cytochrome oxidase activity found in the cytochrome C preparation used.	Potassium Cyanide	80-83	cytochrome c, somatic	Homo sapiens	138-150
3030588-7	1987	PMA treatment of purified human myeloperoxidase (MPO) produced OPD oxidation which is inhibited by superoxide dismutase or 1 mM KCN.	Potassium Cyanide	128-131	myeloperoxidase	Homo sapiens	32-47
3030588-7	1987	PMA treatment of purified human myeloperoxidase (MPO) produced OPD oxidation which is inhibited by superoxide dismutase or 1 mM KCN.	Potassium Cyanide	128-131	myeloperoxidase	Homo sapiens	49-52
3525562-18	1986	HO-1 and HO-2 had similar requirements for cofactor and flavoprotein reductase and were inhibited by heme-ligands (CO, KCN, NaN3).	Potassium Cyanide	119-122	heme oxygenase 1	Rattus norvegicus	0-4
3525562-18	1986	HO-1 and HO-2 had similar requirements for cofactor and flavoprotein reductase and were inhibited by heme-ligands (CO, KCN, NaN3).	Potassium Cyanide	119-122	heme oxygenase 2	Rattus norvegicus	9-13
3516226-1	1986	The bimolecular binding reaction between mono[TyrA14-125I]iodoinsulin and the insulin receptor was investigated at 37 degrees C in intact isolated rat adipocytes in which membrane traffic was inhibited by 1 mM KCN.	Potassium Cyanide	210-213	insulin receptor	Rattus norvegicus	78-94
2418058-9	1986	Depletion of greater than 95% of cellular ATP content by poisoning with KCN in the absence of glucose inhibited pHi recovery.	Potassium Cyanide	72-75	glucose-6-phosphate isomerase	Oryctolagus cuniculus	112-115
3456651-4	1986	The addition of potassium cyanide (50 mM) to intact, rhodanese-loaded erythrocytes containing sodium thiosulfate resulted in its metabolism to thiocyanate.	Potassium Cyanide	16-33	thiosulfate sulfurtransferase, mitochondrial	Mus musculus	53-62
2983715-3	1985	This cytochrome c oxidase activity can be inhibited by low (0.2 mM) concentrations of KCN.	Potassium Cyanide	86-89	cytochrome c, somatic	Homo sapiens	5-17
3004685-4	1985	There appeared to be a relationship between high endogenous catalase levels and the high H2O2 evolution and KCN insensitivity of B. coagulans respiration.	Potassium Cyanide	108-111	catalase	Bos taurus	60-68
3930476-6	1985	KCN also inhibits 5-lipoxygenase at 4 mM, suggesting the presence of a metal-containing prosthetic group.	Potassium Cyanide	0-3	arachidonate 5-lipoxygenase	Homo sapiens	18-32
4044661-4	1985	Transferrin endocytosis was less susceptible to the effects of metabolic inhibitors such as sodium fluoroacetate, potassium cyanide, 2,4, dinitrophenol or carbonylcyanide M-chlorophenyl hydrazone (CCCP) than was iron uptake.	Potassium Cyanide	114-131	transferrin	Rattus norvegicus	0-11
6432695-4	1984	However, treatment of this association with 2,4-dinitrophenol and KCN caused much less inhibition of this phospholipase A activity than did treatment of the rickettsiae with these agents before centrifugation onto the L-cells.	Potassium Cyanide	66-69	phospholipase A and acyltransferase 1	Mus musculus	106-121
6209003-7	1984	Only KCN was comparably effective as an inhibitor of the reaction of cisplatin with alpha 2-macroglobulin; however, KCN was significantly less reactive with preformed platinum(II)-protein bonds than was diethyldithiocarbamate.	Potassium Cyanide	5-8	alpha-2-macroglobulin	Homo sapiens	84-105
2981163-1	1985	In this new method for determining serum guanase activity by use of the Hitachi 736-40 automated analyzer, serum is incubated with a mixture of xanthine oxidase, superoxide dismutase, and catalase; a reagent containing KCN, guanine, nitrotetrazolium blue, and Triton X-100 is added; and the increase in absorbance at 570 and 660 nm is measured for 2.4 min.	Potassium Cyanide	219-222	guanine deaminase	Homo sapiens	41-48
3928536-10	1985	The same was true for slide preparations of cyanomethemoglobin, easily derived from methemoglobin on addition of potassium cyanide.	Potassium Cyanide	113-130	hemoglobin subunit gamma 2	Homo sapiens	49-62
2863291-0	1985	Effects of hydroxyl radical scavengers KCN and CO on ultraviolet light-induced activation of crude soluble guanylate cyclase.	Potassium Cyanide	39-42	guanylate cyclase	Bos taurus	107-124
6330110-5	1984	In contrast, in the presence of KCN, IGF-II binding is decreased by 95% and its apparent affinity increased to 0.21 nM-1.	Potassium Cyanide	32-35	insulin like growth factor 2	Homo sapiens	37-43
6330110-7	1984	In either the absence or presence of KCN, approximately 20% of the cell"s total IGF-II receptors are present in the plasma membranes and approximately 80% in the low density microsomes.	Potassium Cyanide	37-40	insulin like growth factor 2	Homo sapiens	80-86
6330110-8	1984	Insulin induces a 5-fold increase in cell surface IGF-II receptors without a change in affinity when IGF-II binding is measured in the presence of KCN.	Potassium Cyanide	147-150	insulin	Homo sapiens	0-7
6330110-8	1984	Insulin induces a 5-fold increase in cell surface IGF-II receptors without a change in affinity when IGF-II binding is measured in the presence of KCN.	Potassium Cyanide	147-150	insulin like growth factor 2	Homo sapiens	101-107
6330110-11	1984	Addition of KCN prior to insulin abolishes all of these effects of insulin.	Potassium Cyanide	12-15	insulin	Homo sapiens	67-74
6282273-5	1982	The inhibition increased with the concentration of cytochrome c and it was reverted by KCN.	Potassium Cyanide	87-90	cytochrome c, somatic	Homo sapiens	51-63
16663333-4	1983	Ca movement across the tip was also strongly retarded in roots pretreated with 2,4-dinitrophenol or potassium cyanide.	Potassium Cyanide	100-117	NAC domain-containing protein 74	Zea mays	23-26
6307386-2	1983	The process of inactivation is impeded by the addition of inhibitors of myeloperoxidase (KCN, NaN3), of catalase, of methionine but not by the addition of superoxide dismutase, indicating that the mechanism of inactivation is the oxidation of methionine residue by myeloperoxidase-H2O2-halide system.	Potassium Cyanide	89-92	myeloperoxidase	Homo sapiens	72-87
6301583-10	1983	Both KCN and ATZ decreased the oxidation of FMLP by PMN.	Potassium Cyanide	5-8	formyl peptide receptor 1	Homo sapiens	44-48
6196337-4	1983	The reaction was inhibited by pCMB (surface sulfhydryl group specific reagent), by heating, by anaerobic incubation and by catalase (H2O2 scavenger), but it was not inhibited by KCN or NaN3.	Potassium Cyanide	178-181	catalase	Rattus norvegicus	123-131
6386168-8	1984	It is concluded that the actin fibrils of the primary cells and the established line behave differently to changing metabolic conditions and to application of KCN.	Potassium Cyanide	159-162	actin like 6A S homeolog	Xenopus laevis	25-30
6301583-4	1983	At subsaturating concentrations of 3H-FMLP (20 nM), 1 mM cyanide (KCN) increased the binding of 3H-FMLP to human neutrophils (PMN) by 51% +/- 12%.	Potassium Cyanide	66-69	formyl peptide receptor 1	Homo sapiens	38-42
6301583-4	1983	At subsaturating concentrations of 3H-FMLP (20 nM), 1 mM cyanide (KCN) increased the binding of 3H-FMLP to human neutrophils (PMN) by 51% +/- 12%.	Potassium Cyanide	66-69	formyl peptide receptor 1	Homo sapiens	99-103
6684455-2	1983	The influence of oral cytidine diphosphate choline (CDP-choline, citicoline, Somazina) on the experimental toxicity induced by potassium cyanide is investigated.	Potassium Cyanide	127-144	cut like homeobox 1	Homo sapiens	52-55
6293557-1	1982	A kinetic study on ubiquinol-cytochrome c reductase (EC 1.10.2.2) has been undertaken either in situ in KCN-inhibited mitochondria and submitochondrial particles, or in the isolated cytochrome b-c1 complex using ubiquinol-1 and exogenous cytochrome c as substrates.	Potassium Cyanide	104-107	LOC104968582	Bos taurus	29-41
6119752-4	1981	The haloalkane mediated enhancement of the oxidation of cytochrome b-5 in hepatic microsomes from rats fed a high carbohydrate diet was diminished by KCN and the inhibitors of cytochrome P-450, CO and/or metyrapone, as well as by fasting of the experimental animals.	Potassium Cyanide	150-153	cytochrome b5 type A	Rattus norvegicus	56-70
6119752-4	1981	The haloalkane mediated enhancement of the oxidation of cytochrome b-5 in hepatic microsomes from rats fed a high carbohydrate diet was diminished by KCN and the inhibitors of cytochrome P-450, CO and/or metyrapone, as well as by fasting of the experimental animals.	Potassium Cyanide	150-153	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	176-192
6119752-5	1981	The I50 values for KCN inhibition of the effects of the haloalkanes on the re-oxidation of cytochrome b-5 (01 mM) were identical to the I50 for KCN inhibition of stearate desaturase (Oshino et al., 1966).	Potassium Cyanide	19-22	cytochrome b5 type A	Rattus norvegicus	91-105
6452896-7	1981	One Co(II) ion can be removed preferentially by incubation with KCN at high pH, indicating the two ions not to be in an identical environment.	Potassium Cyanide	64-67	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
16661947-5	1981	Low levels of aqueous HCN (2.6 micromoles HCN per gram, corresponding to 0.16 millimolar) injected into sealed dishes gave maximal inhibition of germination, suggesting that the effectiveness of KCN was due to formation of HCN in KCN solutions.	Potassium Cyanide	195-198	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	22-25
16661947-5	1981	Low levels of aqueous HCN (2.6 micromoles HCN per gram, corresponding to 0.16 millimolar) injected into sealed dishes gave maximal inhibition of germination, suggesting that the effectiveness of KCN was due to formation of HCN in KCN solutions.	Potassium Cyanide	230-233	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	22-25
7003100-6	1980	The addition of potassium cyanide (2 mM) significantly inhibited the release of renin from these tissue slices.	Potassium Cyanide	16-33	renin	Rattus norvegicus	80-85
6789499-4	1980	The hemoglobin fraction eluted with the second eluant was applied onto a DEAE-cellulose column and eluted with 0.2 M glycine containing 0.01 percent KCN, resulting in complete isolation of CA-C at high recovery rate.	Potassium Cyanide	149-152	carbonic anhydrase 2	Homo sapiens	189-193
6257667-4	1980	In the difference spectra of the KCN-treated minus the untreated states and of the reduced minus the oxidized states, the cellular and granular fractions of PMN showed sharp absorption maxima identical with the absorption bands of myeloperoxidase (MPO).	Potassium Cyanide	33-36	myeloperoxidase	Oryctolagus cuniculus	231-246
6257667-4	1980	In the difference spectra of the KCN-treated minus the untreated states and of the reduced minus the oxidized states, the cellular and granular fractions of PMN showed sharp absorption maxima identical with the absorption bands of myeloperoxidase (MPO).	Potassium Cyanide	33-36	myeloperoxidase	Oryctolagus cuniculus	248-251
6989357-4	1980	Inhibition of enhanced oxygen uptake by KCN (2mM) and 4-methylpyrazole (0.8 mM) suggested the involvement of the mitochondrial respiratory chain and alcohol dehydrogenase in this phenomenon.	Potassium Cyanide	40-43	aldo-keto reductase family 1 member A1	Rattus norvegicus	149-170
16660162-5	1977	In contrast, the half-maximal inhibition of O(2) uptake rate was obtained at greater KCN concentration in the normal cells (20 muM) compared to copper-deficient cells (2 muM).	Potassium Cyanide	85-88	latexin	Homo sapiens	127-130
7355775-2	1980	B12 values in a cottage cheese meal were lower than controls when concentrations of ascorbic acid greater than but not equal or less than 0.5 mg/ml were added and if KCN was not used during extraction, but when 70 micrograms/ml KCN was added after ascorbic acid exposure B12 was quantitatively recovered.	Potassium Cyanide	166-169	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	0-3
7355775-2	1980	B12 values in a cottage cheese meal were lower than controls when concentrations of ascorbic acid greater than but not equal or less than 0.5 mg/ml were added and if KCN was not used during extraction, but when 70 micrograms/ml KCN was added after ascorbic acid exposure B12 was quantitatively recovered.	Potassium Cyanide	228-231	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	0-3
7355775-3	1980	Serum B12 was variably decreased by lesser concentrations of ascorbic acid but was also quantitatively restored by increasing KCN concentration during extraction.	Potassium Cyanide	126-129	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	6-9
16660664-3	1979	mg Chl) at 21 C. In the presence of the catalase inhibitor KCN, methylviologen catalyzed a Mehler reaction at a rate of 120 to 180 mueq/hr .	Potassium Cyanide	59-62	chloroplastic lipocalin	Zea mays	3-6
32876-0	1978	The reactions of Pseudomonas cytochrome c-551 oxidase with potassium cyanide.	Potassium Cyanide	59-76	cytochrome c, somatic	Homo sapiens	29-41
23176-6	1978	The effects of reagents such as KCN, 2,4-dichlorophenol and aminotriazole on the O-2 generation in this fraction are examined and the nature of the O-2 generating system is discussed.	Potassium Cyanide	32-35	immunoglobulin kappa variable 1D-39	Homo sapiens	81-84
1148252-3	1975	The effect of KCN on cytochrome b-562 was reversed by pentachlorophenol, though the effect of KCN on cytochromes c+c1 and a+a3 was not reversed by this uncoupler.2.	Potassium Cyanide	14-17	cytochrome b, mitochondrial	Rattus norvegicus	21-33
893678-6	1977	Urinary i-PTH per 100 ml GF rose from 8+/-4 ng/min (control) to 170+/-45 ng/min after potassium cyanide.	Potassium Cyanide	86-103	parathyroid hormone	Canis lupus familiaris	10-13
828961-7	1976	In healthy subjects and in pregnant women, correlation was found between the values of ceruloplasmin obtained using both enzymatic and KCN methods.	Potassium Cyanide	135-138	ceruloplasmin	Homo sapiens	87-100
1052169-0	1976	Separation of human hemoglobins by DEAE-cellulose chromatography using glycine-KCN-NaC1 developers.	Potassium Cyanide	79-82	nucleus accumbens associated 1	Homo sapiens	83-87
1052169-1	1976	This chromatographic procedure uses DEAE-cellulose as ion exchanger and glycine-KCN-NaC1 solutions as developers.	Potassium Cyanide	80-83	nucleus accumbens associated 1	Homo sapiens	84-88
188481-5	1977	The KCN difference spectrum of granules from both resting and phagocytizing leukocytes was in agreement with the KCN difference spectrum of myeloperoxidase.	Potassium Cyanide	4-7	myeloperoxidase	Homo sapiens	140-155
188481-5	1977	The KCN difference spectrum of granules from both resting and phagocytizing leukocytes was in agreement with the KCN difference spectrum of myeloperoxidase.	Potassium Cyanide	113-116	myeloperoxidase	Homo sapiens	140-155
188481-6	1977	The affinity of KCN for myeloperoxidase was the same in both resting and phagocytizing leukocytes.	Potassium Cyanide	16-19	myeloperoxidase	Homo sapiens	24-39
188481-7	1977	The KCN-sensitive portion of NAD(P)H oxidase of granules from phagocytizing leukocytes seems to be identical with isolated myeloperoxidase and the myeloperoxidase of resting leukocytes.	Potassium Cyanide	4-7	myeloperoxidase	Homo sapiens	123-138
188481-7	1977	The KCN-sensitive portion of NAD(P)H oxidase of granules from phagocytizing leukocytes seems to be identical with isolated myeloperoxidase and the myeloperoxidase of resting leukocytes.	Potassium Cyanide	4-7	myeloperoxidase	Homo sapiens	147-162
177074-4	1976	In the second place, at higher concentrations of cytochrome c a stimulation of NADH-consuming respiration occurs, which is antimycin-A-resistant, but KCN-sensitive.	Potassium Cyanide	150-153	cytochrome c	Solanum tuberosum	49-61
16659381-4	1975	Under red light, striking photoactivation of NAD kinase was obtained with ATP and subsequently CTP.In the presence of exogenous Mg(2+), which is required for NAD kinase activity, alpha-nitroso-beta-naphthol, cyanide, and dimethylglyoxime, strongly inhibited the activation by red light without affecting the level of NAD kinase in the dark.Of the divalent cations tested with the KCN-treated phytochrome preparation, only Co(2+) was effective for photoactivation of NAD kinase.	Potassium Cyanide	380-383	NAD kinase	Homo sapiens	45-55
1176817-4	1975	Elution of Hb-A2 with a glycine-KCN developer is much less sensitive to minor change in pH of the developer, but is greatly dependent on the pH of the ion exchanger.	Potassium Cyanide	32-35	hemoglobin subunit alpha 2	Homo sapiens	11-16
1148252-3	1975	The effect of KCN on cytochrome b-562 was reversed by pentachlorophenol, though the effect of KCN on cytochromes c+c1 and a+a3 was not reversed by this uncoupler.2.	Potassium Cyanide	94-97	Cardiac cell morphology QTL 1	Rattus norvegicus	113-117
1148252-4	1975	Addition of ATP to aerobic, rat liver mitochondria inhibited with 500 muM KCN under conditions were cytochromes b-562, c+c1 and a+a3 were reduced, caused reduction of cytochrome b-566.	Potassium Cyanide	74-77	Cardiac cell morphology QTL 1	Rattus norvegicus	119-123
1148252-4	1975	Addition of ATP to aerobic, rat liver mitochondria inhibited with 500 muM KCN under conditions were cytochromes b-562, c+c1 and a+a3 were reduced, caused reduction of cytochrome b-566.	Potassium Cyanide	74-77	cytochrome b, mitochondrial	Rattus norvegicus	167-179
170082-2	1975	In the presence of antimycin and KCN the reduction of cytochrome b in phosphorylating submitochondrial particles followed a biphasic first-order kinetics.	Potassium Cyanide	33-36	cytochrome b, mitochondrial	Rattus norvegicus	54-66
237755-6	1975	To examine stereospecific transfer of the hydrogen from NADPH to androstenedione by the purified 17 beta-hydroxysteroid dehydrogenase, the following tritiated cofactors were synthesized: [4-3-H]NADP+ was prepared by catalytic replacement from non-radioactive NADP+ and 3H2O in the presence of potassium cyanide.	Potassium Cyanide	293-310	hydroxysteroid 17-beta dehydrogenase 13	Homo sapiens	97-133
123767-8	1975	(3) With partially inhibitory concentrations of KCN, cytochrome c in either the X- or the KC1 extracted X-fragments showed uncoupler-sensitive, biphasic reduction kinetics upon the addition of NADH to the oligomycin-supplemented system.	Potassium Cyanide	48-51	cytochrome c, somatic	Homo sapiens	53-65
16658941-12	1974	Finally, the nitrate reductase will exhibit a diaphorase activity and reduce the artificial electron acceptor mammalian cytochrome c in flavin-adeninedinucleotide-dependent reaction.Inhibition studies with potassium cyanide, sodium azide, and o-phenanthroline have yielded indirect evidence for metal component (s) of the enzyme.The inhibition of the NADH-requiring enzyme activities by p-hydroxymercuribenzoate has shown that an essential sulfhydryl group is involved in the initial portion of the electron transport.	Potassium Cyanide	206-223	cytochrome c, somatic	Homo sapiens	120-132
29889646-10	2019	In addition, DSP-1053 TDI of CYP1A2 in human liver microsomes was drastically reduced not only by addition of a CYP3A4 inhibitor, but also by addition of potassium cyanide (KCN), which is a trapping agent for iminium ions.	Potassium Cyanide	154-171	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	29-35
4335248-11	1972	Cells treated with 10(-4)M KCN show a decrease in cytochrome oxidase activity to about one-third of control value and an elevated amount of cytochrome c.	Potassium Cyanide	27-30	cytochrome c, somatic	Homo sapiens	140-152
29889646-10	2019	In addition, DSP-1053 TDI of CYP1A2 in human liver microsomes was drastically reduced not only by addition of a CYP3A4 inhibitor, but also by addition of potassium cyanide (KCN), which is a trapping agent for iminium ions.	Potassium Cyanide	173-176	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	29-35
30359465-0	2019	Asymmetric Carboxycyanation of Aldehydes by Cooperative AlF/Onium Salt Catalysts: from Cyanoformate to KCN as Cyanide Source.	Potassium Cyanide	103-106	afamin	Homo sapiens	56-59
30116485-8	2018	It was shown that expression of Bax, Bcl-2, and SOD-2 genes did not significantly differ between groups, while expression of SOD-1 gene and cytochrome c was lower in the KCN group.	Potassium Cyanide	170-173	superoxide dismutase 1	Rattus norvegicus	125-130
29913563-9	2018	In respirometry assays, complex I- and II-driven, coupled and uncoupled respirations and complex IV KCN-sensitive respiration were reduced in Hint2-/- mitochondria.	Potassium Cyanide	100-103	histidine triad nucleotide binding protein 2	Homo sapiens	142-147
30591824-2	2018	To the best of our knowledge, the current synthetic route leading to decyanated products will be the first in terms of a decyanation process which allows the transformation of trisubstituted acetonitriles into alkanes by the incorporation of KCN with the association of in situ-formed HCN and most likely through the extrusion of cyanogen which could not be detected or isolated.	Potassium Cyanide	242-245	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	285-288
30467571-2	2018	The reaction between WO3 and KCN led to the formation of the cluster complex [{W6(mu4-O)2(mu3-CCN)4}(CN)16]10-.	Potassium Cyanide	29-32	adaptor related protein complex 4 subunit mu 1	Homo sapiens	82-85
30467571-4	2018	A similar complex [{W6(mu4-O)2(mu3-As)4}(CN)16]10- containing mu3-As3- ligands instead of mu3-CCN3- ones has been synthesized by the reaction between WO3, As and KCN.	Potassium Cyanide	162-165	adaptor related protein complex 4 subunit mu 1	Homo sapiens	23-26
28623432-6	2017	However, only one candidate homologue for CYS-C1 and NIT4 showed a remarkable up-regulation during KCN exposure.	Potassium Cyanide	99-102	cysteine synthase C1	Arabidopsis thaliana	42-48
29171870-2	2017	To investigate this regulatory mechanism, we studied the interactions of CytcO with potassium cyanide (KCN) upon removal of Rcf1.	Potassium Cyanide	84-101	Rcf1p	Saccharomyces cerevisiae S288C	124-128
29171870-2	2017	To investigate this regulatory mechanism, we studied the interactions of CytcO with potassium cyanide (KCN) upon removal of Rcf1.	Potassium Cyanide	103-106	Rcf1p	Saccharomyces cerevisiae S288C	124-128
28623432-6	2017	However, only one candidate homologue for CYS-C1 and NIT4 showed a remarkable up-regulation during KCN exposure.	Potassium Cyanide	99-102	nitrilase 4	Arabidopsis thaliana	53-57
26676712-4	2016	In particular, with the help of ATP-Red 1, we successfully observed not only the decreased mitochondrial ATP levels in the presence of KCN and starvation state, but also the increased mitochondrial ATP levels in the early stage of cell apoptosis.	Potassium Cyanide	135-138	adenosine deaminase RNA specific B1	Homo sapiens	36-41
27170682-11	2016	An increase in fatty acid-binding protein 3 was observed at 11.5 mg/kg KCN in adult but not in juvenile mice.	Potassium Cyanide	71-74	fatty acid binding protein 3, muscle and heart	Mus musculus	15-43
28318118-6	2017	The expression of NKX2-1 in IL-5+ NPs was significantly lower than KCN NPs and normal controls (p < 0.05).	Potassium Cyanide	67-70	NK2 homeobox 1	Homo sapiens	18-24
26698328-7	2016	When cytochrome c was added, the supercomplex exhibited KCN-sensitive NADH oxidation; thus, the purified supercomplex was active.	Potassium Cyanide	56-59	LOC104968582	Bos taurus	5-17
25918547-4	2015	In in vitro study, protective effects of NAC on KCN cytotoxicity in F3.Olig2 OPCs were investigated via MTT assay and apoptotic signal analysis.	Potassium Cyanide	48-51	X-linked Kx blood group	Homo sapiens	41-44
25918547-4	2015	In in vitro study, protective effects of NAC on KCN cytotoxicity in F3.Olig2 OPCs were investigated via MTT assay and apoptotic signal analysis.	Potassium Cyanide	48-51	oligodendrocyte transcription factor 2	Homo sapiens	71-76
25918547-7	2015	NAC decreased KCN cytotoxicity in F3.Olig2 cells and especially suppressed apoptosis by regulating Bcl2 and p-ERK.	Potassium Cyanide	14-17	X-linked Kx blood group	Homo sapiens	0-3
25918547-7	2015	NAC decreased KCN cytotoxicity in F3.Olig2 cells and especially suppressed apoptosis by regulating Bcl2 and p-ERK.	Potassium Cyanide	14-17	oligodendrocyte transcription factor 2	Homo sapiens	37-42
25070895-6	2014	Inhibition of mitochondria with CCCP, KCN, or rotenone blocked intracellular ATP production, ATP release, intracellular Ca(2+) signaling, induction of the early activation marker CD69, and IL-2 transcription in response to cell stimulation.	Potassium Cyanide	38-41	CD69 molecule	Homo sapiens	179-183
25186256-4	2014	Potassium cyanide decreased ciliary beat frequency in healthy nasal brushings (n = 6) after 60 min (150 muM: 47% fall, p<0.0012; 75 muM: 32% fall, p<0.0001).	Potassium Cyanide	0-17	latexin	Homo sapiens	104-107
25186256-4	2014	Potassium cyanide decreased ciliary beat frequency in healthy nasal brushings (n = 6) after 60 min (150 muM: 47% fall, p<0.0012; 75 muM: 32% fall, p<0.0001).	Potassium Cyanide	0-17	latexin	Homo sapiens	135-138
25070895-6	2014	Inhibition of mitochondria with CCCP, KCN, or rotenone blocked intracellular ATP production, ATP release, intracellular Ca(2+) signaling, induction of the early activation marker CD69, and IL-2 transcription in response to cell stimulation.	Potassium Cyanide	38-41	interleukin 2	Homo sapiens	189-193
24425765-7	2014	Potassium cyanide chemically reduced COX activity, decreasing GSIS and thus reinforcing the link between islet COX activity and GSIS.	Potassium Cyanide	0-17	coproporphyrinogen oxidase	Rattus norvegicus	37-40
24425765-7	2014	Potassium cyanide chemically reduced COX activity, decreasing GSIS and thus reinforcing the link between islet COX activity and GSIS.	Potassium Cyanide	0-17	coproporphyrinogen oxidase	Rattus norvegicus	111-114
24308563-5	2014	Pre-treatment of rats with MECP inhibited KCN-induced increases in LPO, NO, and glutamate levels and AChE activity as well as decreases in brain GSH level and SOD and CAT activities.	Potassium Cyanide	42-45	acetylcholinesterase	Rattus norvegicus	101-105
24308563-5	2014	Pre-treatment of rats with MECP inhibited KCN-induced increases in LPO, NO, and glutamate levels and AChE activity as well as decreases in brain GSH level and SOD and CAT activities.	Potassium Cyanide	42-45	catalase	Rattus norvegicus	167-170
24308563-3	2014	Intraperitoneal injection of the sublethal dose of KCN (3 mg/Kg bwt) into rats increased, 24 hrs later, lipid peroxidation (LPO), nitric oxide (NO), glutamate levels and acetylcholinesterase (AChE) activity in hippocampus, striatum and cerebral cortex.	Potassium Cyanide	51-54	acetylcholinesterase	Rattus norvegicus	192-196
24308563-4	2014	KCN also decreased brain glutathione (GSH) level and superoxide dismutase (SOD) and catalase (CAT) activities in these animals.	Potassium Cyanide	0-3	catalase	Rattus norvegicus	84-92
23929717-4	2013	Hepatic and renal TST activity increased by 0.5 LD50 KCN but diminished by >=2.0 LD50.	Potassium Cyanide	53-56	thiosulfate sulfurtransferase, mitochondrial	Mus musculus	18-21
24308563-4	2014	KCN also decreased brain glutathione (GSH) level and superoxide dismutase (SOD) and catalase (CAT) activities in these animals.	Potassium Cyanide	0-3	catalase	Rattus norvegicus	94-97
23929717-1	2013	We assessed the dose-dependent effect of potassium cyanide (KCN) on thiosulfate sulfurtransferase (TST), 3-mercaptopyruvate sulfurtransferase (3-MPST), and cystathionine lambda-lyase (CST) activities in mice.	Potassium Cyanide	60-63	thiosulfate sulfurtransferase, mitochondrial	Mus musculus	68-97
23929717-1	2013	We assessed the dose-dependent effect of potassium cyanide (KCN) on thiosulfate sulfurtransferase (TST), 3-mercaptopyruvate sulfurtransferase (3-MPST), and cystathionine lambda-lyase (CST) activities in mice.	Potassium Cyanide	60-63	thiosulfate sulfurtransferase, mitochondrial	Mus musculus	99-102
23924851-5	2013	OH-Cbl can be released from mAb and Fc-fusion proteins by conversion with potassium cyanide to CN-Cbl, which does not bind.	Potassium Cyanide	74-91	Cbl proto-oncogene	Homo sapiens	3-6
23868305-4	2013	In this study, we investigated whether NNMT expression in SH-SY5Y conferred protection against mitotoxicity induced by rotenone, potassium cyanide (KCN), 2,4-dinitrophenol, and 6-hydroxydopamine, and whether any effects observed were mediated via increased MeN production.	Potassium Cyanide	129-146	nicotinamide N-methyltransferase	Homo sapiens	39-43
23868305-4	2013	In this study, we investigated whether NNMT expression in SH-SY5Y conferred protection against mitotoxicity induced by rotenone, potassium cyanide (KCN), 2,4-dinitrophenol, and 6-hydroxydopamine, and whether any effects observed were mediated via increased MeN production.	Potassium Cyanide	148-151	nicotinamide N-methyltransferase	Homo sapiens	39-43
23868305-5	2013	NNMT expression abolished the toxic effects of KCN, 2,4-dinitrophenol, and 6-hydroxydopamine, and reduced that of rotenone.	Potassium Cyanide	47-50	nicotinamide N-methyltransferase	Homo sapiens	0-4
23230142-5	2013	Antimycin A and potassium cyanide effectively induced nonspecific autophagy, but not mitophagy, in a wild-type strain of Saccharomyces cerevisiae; however, low or no autophagic activity was measured in strains deficient for genes that encode proteins involved in mitophagy, including ATG32, ATG11 and BCK1.	Potassium Cyanide	16-33	mitophagy protein ATG32	Saccharomyces cerevisiae S288C	284-289
23605642-4	2013	Molecular docking tool was used to elucidate a comparative binding mode of the crab and rat SOD with potent inhibitors of SOD such as hydrogen peroxide (H2O2), potassium cyanide (KCN) and sodium dodecyl sulphate (SDS).	Potassium Cyanide	160-177	superoxide dismutase 2	Rattus norvegicus	92-95
23605642-4	2013	Molecular docking tool was used to elucidate a comparative binding mode of the crab and rat SOD with potent inhibitors of SOD such as hydrogen peroxide (H2O2), potassium cyanide (KCN) and sodium dodecyl sulphate (SDS).	Potassium Cyanide	160-177	superoxide dismutase 2	Rattus norvegicus	122-125
23605642-4	2013	Molecular docking tool was used to elucidate a comparative binding mode of the crab and rat SOD with potent inhibitors of SOD such as hydrogen peroxide (H2O2), potassium cyanide (KCN) and sodium dodecyl sulphate (SDS).	Potassium Cyanide	179-182	superoxide dismutase 2	Rattus norvegicus	92-95
23605642-4	2013	Molecular docking tool was used to elucidate a comparative binding mode of the crab and rat SOD with potent inhibitors of SOD such as hydrogen peroxide (H2O2), potassium cyanide (KCN) and sodium dodecyl sulphate (SDS).	Potassium Cyanide	179-182	superoxide dismutase 2	Rattus norvegicus	122-125
23605642-5	2013	The predicted valid structure of crab MnSOD did not show any interaction with KCN but close interaction with H2O2 and SDS.	Potassium Cyanide	78-81	superoxide dismutase 2	Rattus norvegicus	38-43
22369111-8	2013	Accordingly, the expression of a dominant negative form of DRP1 (K38A mutant) reduced the biogenic response in fibroblasts challenged with 6 muM KCN.	Potassium Cyanide	145-148	collapsin response mediator protein 1	Homo sapiens	59-63
23419198-13	2013	Our data imply that hemin dicyanide formed in the presence of KCN remains weakly bound to denatured beta-globin, thereby counteracting aggregation, such that the refolding yield is enhanced.	Potassium Cyanide	62-65	hemoglobin subunit beta	Bos taurus	100-111
23230142-5	2013	Antimycin A and potassium cyanide effectively induced nonspecific autophagy, but not mitophagy, in a wild-type strain of Saccharomyces cerevisiae; however, low or no autophagic activity was measured in strains deficient for genes that encode proteins involved in mitophagy, including ATG32, ATG11 and BCK1.	Potassium Cyanide	16-33	autophagy protein ATG11	Saccharomyces cerevisiae S288C	291-296
23230142-5	2013	Antimycin A and potassium cyanide effectively induced nonspecific autophagy, but not mitophagy, in a wild-type strain of Saccharomyces cerevisiae; however, low or no autophagic activity was measured in strains deficient for genes that encode proteins involved in mitophagy, including ATG32, ATG11 and BCK1.	Potassium Cyanide	16-33	mitogen-activated protein kinase kinase kinase BCK1	Saccharomyces cerevisiae S288C	301-305
23026561-4	2013	Primary cultures of cortical neurons were challenged with toxic concentrations of Abeta upon chemical inhibition of COX with potassium cyanide (KCN).	Potassium Cyanide	125-142	amyloid beta precursor protein	Homo sapiens	82-87
23159310-7	2013	In addition, 17 of these leptin responsive neurons were excited by the intra-carotid injections of KCN (80 mug/0.1 ml).	Potassium Cyanide	99-102	leptin	Rattus norvegicus	25-31
23159310-8	2013	Furthermore, the excitatory response of these single units to KCN was potentiated (59-83%) immediately following the leptin injection.	Potassium Cyanide	62-65	leptin	Rattus norvegicus	117-123
23026561-4	2013	Primary cultures of cortical neurons were challenged with toxic concentrations of Abeta upon chemical inhibition of COX with potassium cyanide (KCN).	Potassium Cyanide	125-142	cytochrome c oxidase subunit 8A	Homo sapiens	116-119
23026561-4	2013	Primary cultures of cortical neurons were challenged with toxic concentrations of Abeta upon chemical inhibition of COX with potassium cyanide (KCN).	Potassium Cyanide	144-147	amyloid beta precursor protein	Homo sapiens	82-87
23026561-7	2013	KCN pre-treatment was also shown to enhance the rise of cytosolic Ca(2+) levels triggered by Abeta and thapsigargin, a widely used ER stressor.	Potassium Cyanide	0-3	amyloid beta precursor protein	Homo sapiens	93-98
23026561-9	2013	Similarly, the increase in GRP78 and XBP-1 protein levels was shown to be higher in neurons treated with Abeta or thapsigargin in the presence of KCN in comparison with levels determined in neurons treated with the neurotoxins alone.	Potassium Cyanide	146-149	heat shock protein family A (Hsp70) member 5	Homo sapiens	27-32
23026561-9	2013	Similarly, the increase in GRP78 and XBP-1 protein levels was shown to be higher in neurons treated with Abeta or thapsigargin in the presence of KCN in comparison with levels determined in neurons treated with the neurotoxins alone.	Potassium Cyanide	146-149	X-box binding protein 1	Homo sapiens	37-42
23026561-9	2013	Similarly, the increase in GRP78 and XBP-1 protein levels was shown to be higher in neurons treated with Abeta or thapsigargin in the presence of KCN in comparison with levels determined in neurons treated with the neurotoxins alone.	Potassium Cyanide	146-149	amyloid beta precursor protein	Homo sapiens	105-110
23026561-10	2013	Although the decrease in cell survival, the activation of caspase-9- and -3-mediated apoptotic cell death observed in Abeta- and thapsigargin-treated neurons were also potentiated by KCN, this effect is less pronounced than that observed in Ca(2+) signalling and UPR.	Potassium Cyanide	183-186	caspase 9	Homo sapiens	58-75
23026561-10	2013	Although the decrease in cell survival, the activation of caspase-9- and -3-mediated apoptotic cell death observed in Abeta- and thapsigargin-treated neurons were also potentiated by KCN, this effect is less pronounced than that observed in Ca(2+) signalling and UPR.	Potassium Cyanide	183-186	amyloid beta precursor protein	Homo sapiens	118-123
22763120-3	2012	Cell surface biotinylation studies reveal that plasma membrane GLUT1 levels are increased two- to threefold by cellular glucose depletion, AICAR or KCN treatment, and that these increases are prevented by Compound C and by AMPK alpha1- or alpha2-knockdown.	Potassium Cyanide	148-151	solute carrier family 2 (facilitated glucose transporter), member 1	Mus musculus	63-68
22554042-3	2012	The results showed that pretreatment with 20 microM KCN alleviated stress-induced oxidative damage in plant cells and clearly induced the activity of alternative oxidase (AOX) and the ethylene production.	Potassium Cyanide	52-55	ubiquinol oxidase 4, chloroplastic/chromoplastic	Cucumis sativus	150-169
22554042-3	2012	The results showed that pretreatment with 20 microM KCN alleviated stress-induced oxidative damage in plant cells and clearly induced the activity of alternative oxidase (AOX) and the ethylene production.	Potassium Cyanide	52-55	ubiquinol oxidase 4, chloroplastic/chromoplastic	Cucumis sativus	171-174