PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 12419536-3 2002 Here we show that, in contrast to APP(V717F) Tg mice expressing apoE, APP(V717F) Tg mice deficient in apoE develop anti-Abeta immunoreactive multifocal aggregates, which contain the beta-cleaved C-terminal fragments (beta-CTFs) of APP. beta-ctfs 217-226 apolipoprotein E Mus musculus 102-106 12419536-4 2002 Tg mice deficient in apoE also display altered levels of mature full-length APP, increased amounts of beta-CTFs, as well as elevated levels of Abeta(1-40) and Abeta(1-42) in an age- and region-dependent manner when compared to Tg mice expressing apoE. beta-ctfs 102-111 apolipoprotein E Mus musculus 21-25