PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 32896690-9 2020 In mice, ALN-F12 led to dose-dependent reductions in platelet and fibrin accumulation in the venous electrolytic-injury model and in the time to occlusion in the ferric chloride arterial thrombosis model. ferric chloride 162-177 coagulation factor XII (Hageman factor) Mus musculus 13-16 32994008-3 2020 For the in-situ polymerization of PPy-NPs, ferric chloride hexahydrate (FeCl3.6H2O) was introduced as an oxidant into the blended solution of PCL and pyrrole monomers. ferric chloride 43-70 polycystic kidney disease 2-like 1 Mus musculus 142-145 32143019-0 2020 Synthesis of 11,12-dihydro benzo[c]phenanthridines via a Pd-catalyzed unusual construction of isocoumarin ring/FeCl3-mediated intramolecular arene-allyl cyclization: First identification of a benzo[c]phenanthridine based PDE4 inhibitor. ferric chloride 111-116 phosphodiesterase 4A Homo sapiens 221-225 32205561-9 2020 CONCLUSION: DPP-4 inhibition appeared to improve the FeCl3-induced thrombosis in mice that received stress, possibly via the improvement of ADAMTS13 and oxidative stress, suggesting that DPP-4 could become a novel therapeutic target for chronic psychological stress-related thrombotic events in metabolic cardiovascular disorders. ferric chloride 53-58 dipeptidylpeptidase 4 Mus musculus 12-17 32205561-9 2020 CONCLUSION: DPP-4 inhibition appeared to improve the FeCl3-induced thrombosis in mice that received stress, possibly via the improvement of ADAMTS13 and oxidative stress, suggesting that DPP-4 could become a novel therapeutic target for chronic psychological stress-related thrombotic events in metabolic cardiovascular disorders. ferric chloride 53-58 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 Mus musculus 140-148 32205561-9 2020 CONCLUSION: DPP-4 inhibition appeared to improve the FeCl3-induced thrombosis in mice that received stress, possibly via the improvement of ADAMTS13 and oxidative stress, suggesting that DPP-4 could become a novel therapeutic target for chronic psychological stress-related thrombotic events in metabolic cardiovascular disorders. ferric chloride 53-58 dipeptidylpeptidase 4 Mus musculus 187-192 32144232-3 2019 The results indicated that the mixture solution of FeCl3- and AlCl3- modified CSB (Fe-Al/CSB) showed the best adsorption performance for NO3-N removal. ferric chloride 51-56 NBL1, DAN family BMP antagonist Homo sapiens 137-140 31383642-8 2019 Moreover, platelet recruitment and fibrin(ogen) accumulation were significantly higher in F8-/-/PN-1-/- mice than in F8-/-mice in the ferric chloride-induced mesenteric vessel injury model. ferric chloride 134-149 serine (or cysteine) peptidase inhibitor, clade E, member 2 Mus musculus 96-100 31289200-7 2020 The injection of oxLDL into wild type mice strongly promoted FeCl3 induced carotid thrombosis in vivo, which was prevented by pharmacological inhibition of PDE3A. ferric chloride 61-66 phosphodiesterase 3A, cGMP inhibited Mus musculus 156-161 30794417-3 2019 In contrast with Sn(OTf)2, the reaction of 3-( tert-butylperoxy)indolin-2-one derivatives with FeCl3 afforded the Hock fragmentation product via C-C bond cleavage. ferric chloride 95-100 POU class 2 homeobox 2 Homo sapiens 20-25 31248335-12 2019 Next, we assessed the effect of extracellular PAD4 on platelet-plug formation after ferric chloride-induced injury of mesenteric venules. ferric chloride 84-99 MMTV LTR integration site 4 Mus musculus 46-50 31027312-7 2019 MS-1 possessed markedly thrombolytic activity evaluated by plasminogen activator inhibitior-1, fibrin degradation products, and D-dimer levels using rats plasma, and recanalization rate by FeCl3-induced carotid artery thrombosis in mice. ferric chloride 189-194 actin-binding Rho activating protein Rattus norvegicus 0-4 31002695-4 2019 Here, using mice model and recombinant human gelsolin (rhuGSN), we demonstrate the antithrombotic effect of gelsolin in ferric chloride induced thrombosis in carotid artery and thrombin induced acute pulmonary thromboembolism. ferric chloride 120-135 gelsolin Homo sapiens 108-116 30967391-6 2019 Platelets from DGKzeta-KO mice accumulated faster on collagen-coated microfluidic surfaces under conditions of arterial shear and stopped blood flow faster after ferric chloride-induced carotid artery injury. ferric chloride 162-177 diacylglycerol kinase zeta Mus musculus 15-22 31475996-2 2019 By employing a FeCl3 and BF3 OEt2 co-catalytic strategy, the ring-opening of 1-tosyl-2,3-dihydro-1H-pyrroles by selective cleavage of the C(sp2)-N bond and subsequent annulation have been achieved to access 1-tosyl-2,3-dihydro-1H-azepines with excellent regioselectivity, offering a new avenue for cycloaddition through the ring-opening of non-strained-ring-based units. ferric chloride 15-20 Sp2 transcription factor Homo sapiens 138-143 31430934-2 2019 The optimal ratio of FeCl3/EDA was found to be close to 1/3 under the consideration of the electrocatalytic performance, such as better oxygen reduction reaction (ORR) and higher power density. ferric chloride 21-26 ectodysplasin A Homo sapiens 27-30 29390191-3 2019 RESULTS: Morphometric analysis of vascular lesions generated by 10% ferric chloride (FeCl3) revealed that tamoxifen-inducible endothelial PTP1B deletion (Tie2.ERT2-Cre x PTP1Bfl/fl; End.PTP1B knockout, KO) significantly increased neointima formation, and reduced numbers of (endothelial lectin-positive) luminal cells in End.PTP1B-KO mice suggested impaired lesion re-endothelialization. ferric chloride 68-83 protein tyrosine phosphatase, non-receptor type 1 Mus musculus 138-143 30425049-8 2019 TMX1-knockout mice had increased incorporation of platelets into a growing thrombus in an FeCl3-induced mesenteric arterial injury model, as well as shortened tail-bleeding times. ferric chloride 90-95 thioredoxin-related transmembrane protein 1 Mus musculus 0-4 30602303-5 2019 Approach and Results- Using a ferric chloride-induced thrombosis model, we found that the occlusion time was significantly reduced in conventional Klf11 knockout mice, whereas bone marrow transplantation could not rescue this phenotype, suggesting that vascular KLF11 is critical for inhibition of arterial thrombosis. ferric chloride 30-45 Kruppel-like factor 11 Mus musculus 147-152 30602303-5 2019 Approach and Results- Using a ferric chloride-induced thrombosis model, we found that the occlusion time was significantly reduced in conventional Klf11 knockout mice, whereas bone marrow transplantation could not rescue this phenotype, suggesting that vascular KLF11 is critical for inhibition of arterial thrombosis. ferric chloride 30-45 Kruppel-like factor 11 Mus musculus 262-267 30787021-12 2019 ELMO1-/- mice also exhibited a shorter time to occlusion using the ferric-chloride injury model and reduced bleeding times compared with WT littermate controls. ferric chloride 67-82 engulfment and cell motility 1 Mus musculus 0-5 29390191-3 2019 RESULTS: Morphometric analysis of vascular lesions generated by 10% ferric chloride (FeCl3) revealed that tamoxifen-inducible endothelial PTP1B deletion (Tie2.ERT2-Cre x PTP1Bfl/fl; End.PTP1B knockout, KO) significantly increased neointima formation, and reduced numbers of (endothelial lectin-positive) luminal cells in End.PTP1B-KO mice suggested impaired lesion re-endothelialization. ferric chloride 85-90 protein tyrosine phosphatase, non-receptor type 1 Mus musculus 138-143 29390191-3 2019 RESULTS: Morphometric analysis of vascular lesions generated by 10% ferric chloride (FeCl3) revealed that tamoxifen-inducible endothelial PTP1B deletion (Tie2.ERT2-Cre x PTP1Bfl/fl; End.PTP1B knockout, KO) significantly increased neointima formation, and reduced numbers of (endothelial lectin-positive) luminal cells in End.PTP1B-KO mice suggested impaired lesion re-endothelialization. ferric chloride 85-90 TEK receptor tyrosine kinase Mus musculus 154-158 30444570-8 2019 In a ferric chloride-induced mesenteric arteriole thrombosis model, megakaryocyte/platelet-specific Shp2-deficient mice showed less thrombi shedding than wild-type mice, although their occlusion times were comparable. ferric chloride 5-20 protein tyrosine phosphatase, non-receptor type 11 Mus musculus 100-104 30453345-6 2018 Furthermore, Coro1A-deficient mice displayed a defect in ferric chloride-induced arterial thrombosis with prolonged thrombus formation and reduced thrombus size. ferric chloride 57-72 coronin, actin binding protein 1A Mus musculus 13-19 30729213-8 2018 A synergistic effect was observed after iron chloride 1,000 muM plus nickel chloride 200 muM treatment in all assays. ferric chloride 40-53 latexin Homo sapiens 60-63 30729213-9 2018 Moreover, the same effect was observed in the pair iron chloride 200 muM plus nickel chloride 1,000 muM in the LDH and NRU assays. ferric chloride 51-64 latexin Homo sapiens 69-72 30729213-11 2018 Iron chloride at a concentration of 200 muM protects mitochondria from nickel chloride toxicity. ferric chloride 0-13 latexin Homo sapiens 40-43 30241044-3 2018 The experimental system received ferric chloride (FeCl3) dosing at 10 mgFe L-1 in the sewer reactor whereas the control system received none. ferric chloride 33-48 immunoglobulin kappa variable 1-16 Homo sapiens 75-78 30241044-3 2018 The experimental system received ferric chloride (FeCl3) dosing at 10 mgFe L-1 in the sewer reactor whereas the control system received none. ferric chloride 50-55 immunoglobulin kappa variable 1-16 Homo sapiens 75-78 30241044-5 2018 The FeCl3-dosed experimental system displayed a decreased sulfide concentration (by 4.3 +- 0.5 mgS L-1) in sewer effluent, decreased phosphate concentration (by 4.7 +- 0.5 mgP L-1) in biological treatment reactor effluent, and decreased hydrogen sulfide concentration in biogas (911.5 +- 189.9 ppm to 130.0 +- 5.9 ppm), as compared with the control system. ferric chloride 4-9 immunoglobulin kappa variable 1-16 Homo sapiens 99-102 30241044-5 2018 The FeCl3-dosed experimental system displayed a decreased sulfide concentration (by 4.3 +- 0.5 mgS L-1) in sewer effluent, decreased phosphate concentration (by 4.7 +- 0.5 mgP L-1) in biological treatment reactor effluent, and decreased hydrogen sulfide concentration in biogas (911.5 +- 189.9 ppm to 130.0 +- 5.9 ppm), as compared with the control system. ferric chloride 4-9 immunoglobulin kappa variable 1-16 Homo sapiens 176-179 30058211-0 2018 Elastin Stabilization Through Polyphenol and Ferric Chloride Combined Treatment for the Enhancement of Bioprosthetic Heart Valve Anticalcification. ferric chloride 45-60 elastin Homo sapiens 0-7 30058211-5 2018 We investigated the combined tannic acid (TA) or epigallocatechin gallate (EGCG) with ferric chloride to stabilize elastin and prevent calcification. ferric chloride 86-101 elastin Homo sapiens 115-122 30354235-10 2018 Transfusion of rADAMTS13-loaded platelets into Adamts13-/- mice dramatically reduces the rate of thrombus formation in the mesenteric arterioles after FeCl3 injury. ferric chloride 151-156 ADAM metallopeptidase with thrombospondin type 1 motif, 13 Rattus norvegicus 15-24 30354235-10 2018 Transfusion of rADAMTS13-loaded platelets into Adamts13-/- mice dramatically reduces the rate of thrombus formation in the mesenteric arterioles after FeCl3 injury. ferric chloride 151-156 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 Mus musculus 47-55 30077102-6 2018 In contrast, FeCl3 decreased cell wall-bound POD activity. ferric chloride 13-18 peroxidase Glycine max 45-48 30261531-7 2018 Furthermore, in the hyperlipidemic ApoE-deficient mouse model, TLR2 deficiency was shown to protect from ferric chloride-induced carotid artery thrombosis. ferric chloride 105-120 apolipoprotein E Mus musculus 35-39 30300909-10 2018 Aspirin treatment or depletion of the TXAS, TP or TXAS/TP gene significantly attenuated the exaggerated vascular reactivity by vasoconstrictors and vasodilators and efficiently reduced platelet adhesion to the mesenteric endothelium under FeCl3 stimulation. ferric chloride 239-244 thromboxane A synthase 1, platelet Mus musculus 38-42 30300909-10 2018 Aspirin treatment or depletion of the TXAS, TP or TXAS/TP gene significantly attenuated the exaggerated vascular reactivity by vasoconstrictors and vasodilators and efficiently reduced platelet adhesion to the mesenteric endothelium under FeCl3 stimulation. ferric chloride 239-244 thromboxane A synthase 1, platelet Mus musculus 50-54 29963675-3 2018 Here, we report a facile approach to prepare tough physical hydrogel films by spin-coating of a poly(acrylic acid-co-acrylamide) (P(AAc-co-AAm)) solution and subsequent gelation in FeCl3 solution to form carboxyl-Fe3+ coordination complexes. ferric chloride 181-186 spindlin 1 Homo sapiens 78-82 30185436-7 2018 VAMP2Delta3Delta mice showed no deficiency, whereas VAMP8-/- mice had attenuated formation of occlusive thrombi upon FeCl3-induced arterial injury but no excessive bleeding upon tail transection. ferric chloride 117-122 vesicle-associated membrane protein 8 Mus musculus 52-57 30150285-6 2018 EGF stimulated ex vivo adhesion of platelets to collagen-coated microfluidic channels, whereas systemic EGF injection increased initial platelet deposition in FeCl3-damaged murine carotid arteries. ferric chloride 159-164 epidermal growth factor Mus musculus 104-107 29974253-0 2018 Electronic properties of FeCl3 and CrO3 interacting with GaN nanotubes from density functional calculations. ferric chloride 25-30 gigaxonin Homo sapiens 57-60 29704172-4 2018 Vascular injury was induced by the application of 10% ferric chloride to the carotid artery for 3 min in ApoE-deficient mice. ferric chloride 54-69 apolipoprotein E Mus musculus 105-109 29636422-14 2018 Importantly, mrLTF (recombinant mouse LTF) reduced the cytotoxicity of lysed RBC and FeCl3 to brain cells in culture. ferric chloride 85-90 lactotransferrin Mus musculus 15-18 29941457-8 2018 In vivo, MEKK3-/- mice showed delayed thrombus formation following FeCl3-induced carotid artery injury. ferric chloride 67-72 mitogen-activated protein kinase kinase kinase 3 Mus musculus 9-14 29747503-2 2018 Reaction of FeCl3 with 2,5-dichloro-3,6-dihydroxy-1,4-benzoquinone (LH2) in the presence of (NMe4)Cl gave the compound (NMe4)2[LFeCl2]. ferric chloride 12-17 NME/NM23 nucleoside diphosphate kinase 4 Homo sapiens 93-97 29747503-2 2018 Reaction of FeCl3 with 2,5-dichloro-3,6-dihydroxy-1,4-benzoquinone (LH2) in the presence of (NMe4)Cl gave the compound (NMe4)2[LFeCl2]. ferric chloride 12-17 NME/NM23 nucleoside diphosphate kinase 4 Homo sapiens 120-124 29421655-5 2018 ADAMTS18 deficiency accelerated FeCl3-induced carotid artery thrombosis and aggravated postischemic cerebral infarction in mice. ferric chloride 32-37 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18 Mus musculus 0-8 29079502-2 2018 The aim of this study was to investigate the effects of a 12/15-LOX inhibitor, LOXBlock-1(LB1), in mice using a FeCl3-induced permanent distal MCAO model and FeCl3-induced ischemia/thrombolysis with tPA. ferric chloride 112-117 cytoskeleton associated protein 2 Mus musculus 90-93 29386206-11 2018 NCBE expression increased while IRP2 expression decreased after GMH/iron trichloride. ferric chloride 68-84 iron responsive element binding protein 2 Rattus norvegicus 32-36 29386206-12 2018 Deferoxamine ameliorated both the GMH-induced and iron trichloride-induced decrease of IRP2 and decreased NCBE expressions. ferric chloride 50-66 iron responsive element binding protein 2 Rattus norvegicus 87-91 29386206-12 2018 Deferoxamine ameliorated both the GMH-induced and iron trichloride-induced decrease of IRP2 and decreased NCBE expressions. ferric chloride 50-66 solute carrier family 4 member 10 Rattus norvegicus 106-110 29079502-5 2018 For FeCl3-induced ischemia/thrombolysis experiments, 10% FeCl3 was preferred so as to obtain reperfusion with tPA in CD1 mice. ferric chloride 57-62 CD1 antigen complex Mus musculus 117-120 29079502-8 2018 FeCl3-induced distal MCAO caused an increase in 12/15-LOX signal in the ischemic cortex with an increase in MDA2 and AIF immunoreactivity. ferric chloride 0-5 arachidonate 15-lipoxygenase Mus musculus 48-57 28826135-6 2017 Overall, leachate treated with coagulation +10.6 BV GAC +10.6 BV ion exchange showed the highest removal of C1 (39% - FeCl3, 8% - PACl), C2 (74% - FeCl3, 68% - PACl) and no C3 removal; whereas only 52% C2 and no C1 and C3 removal was observed in raw leachate treated with 10.6 BV GAC + 10.6 BV ion exchange only. ferric chloride 118-123 glutaminase Homo sapiens 52-55 29079502-14 2018 This study not only shows the effects of LB1 treatment in distal MCAO but also confirms that FeCl3-induced MCAO model can be a useful tool to screen novel treatment options in stroke. ferric chloride 93-98 cytoskeleton associated protein 2 Mus musculus 41-44 29215030-10 2017 Time to formation of thrombi in a FeCl3-induced thrombosis model was significantly shortened in the TRAF3 knockout mice. ferric chloride 34-39 TNF receptor-associated factor 3 Mus musculus 100-105 29087203-1 2017 The facile synthesis of a porous heterogeneous BINOL-derived chiral phosphoric acid BiCz-POF-1 using the mild, FeCl3-promoted oxidative polymerization is reported. ferric chloride 111-116 fragile X messenger ribonucleoprotein 1 Homo sapiens 89-94 28882875-6 2017 In a ferric chloride-induced mesenteric arteriolar thrombosis model, VPS34-/- mice exhibited a prolonged vessel occlusion time compared with wild-type mice (42.05+-4.09 versus 18.30+-2.47 minutes). ferric chloride 5-20 phosphatidylinositol 3-kinase catalytic subunit type 3 Mus musculus 69-74 28826135-6 2017 Overall, leachate treated with coagulation +10.6 BV GAC +10.6 BV ion exchange showed the highest removal of C1 (39% - FeCl3, 8% - PACl), C2 (74% - FeCl3, 68% - PACl) and no C3 removal; whereas only 52% C2 and no C1 and C3 removal was observed in raw leachate treated with 10.6 BV GAC + 10.6 BV ion exchange only. ferric chloride 147-152 glutaminase Homo sapiens 52-55 28815927-3 2017 The conformational changes of Tf mixed with FeCl3 , GdCl3 , C60 (OH)22 or Gd@C82 (OH)22 were obtained by SAXS. ferric chloride 44-49 transferrin Homo sapiens 30-32 28815927-4 2017 The results demonstrate that Tf homodimers can be decomposed into monomers in the presence of FeCl3 , GdCl3 or C60 (OH)22 , but associated into tetramers in the presence of Gd@C82 (OH)22 . ferric chloride 94-99 transferrin Homo sapiens 29-31 28815927-5 2017 The larger change of SAXS shapes between Tf+C60 (OH)22 and Tf+FeCl3 implies that C60 (OH)22 is bound to Tf, blocking the iron-binding site. ferric chloride 62-67 transferrin Homo sapiens 59-61 28815927-5 2017 The larger change of SAXS shapes between Tf+C60 (OH)22 and Tf+FeCl3 implies that C60 (OH)22 is bound to Tf, blocking the iron-binding site. ferric chloride 62-67 transferrin Homo sapiens 59-61 28550640-12 2017 Taken together, these data indicated that endogenous TFPI from VSMCs inhibited ferric chloride-induced arterial thrombosis without causing hemostatic effects. ferric chloride 79-94 tissue factor pathway inhibitor Mus musculus 53-57 28779890-9 2017 The activity of CT-K in the presence of FeCl3 was monitored fluorimetrically. ferric chloride 40-45 cathepsin K Homo sapiens 16-20 28779890-13 2017 Treating dentin with 1.8% FeCl3 was effective to preserve the structure of collagen against CT-K. ferric chloride 26-31 cathepsin K Homo sapiens 92-96 28779890-15 2017 FeCl3 at concentration of 0.08% was able to suppress CT-K activity. ferric chloride 0-5 cathepsin K Homo sapiens 53-57 28799234-15 2017 ARHGEF10 knockout resulted in prolonged tail bleeding time and inhibited the stable thrombus formation induced by FeCl3 in the carotid artery. ferric chloride 114-119 Rho guanine nucleotide exchange factor (GEF) 10 Mus musculus 0-8 28678391-9 2017 Consistently, we show in an in vivo model of FeCl3 -induced arterial thrombosis that IFN-lambda2/IL-28A exerts strong antithrombotic potential. ferric chloride 45-50 interferon lambda 2 Homo sapiens 85-96 28678391-9 2017 Consistently, we show in an in vivo model of FeCl3 -induced arterial thrombosis that IFN-lambda2/IL-28A exerts strong antithrombotic potential. ferric chloride 45-50 interferon lambda 2 Homo sapiens 97-103 28576878-3 2017 We generated a new conditional knockout mouse model and found that Tie2-Cre/ERp72fl/fl mice with blood and endothelial cells lacking ERp72 had prolonged tail bleeding times and decreased platelet accumulation in laser-induced cremaster arteriole injury and FeCl3-induced mesenteric arterial injury. ferric chloride 257-262 TEK receptor tyrosine kinase Mus musculus 67-71 28576878-3 2017 We generated a new conditional knockout mouse model and found that Tie2-Cre/ERp72fl/fl mice with blood and endothelial cells lacking ERp72 had prolonged tail bleeding times and decreased platelet accumulation in laser-induced cremaster arteriole injury and FeCl3-induced mesenteric arterial injury. ferric chloride 257-262 protein disulfide isomerase associated 4 Mus musculus 76-81 28576878-3 2017 We generated a new conditional knockout mouse model and found that Tie2-Cre/ERp72fl/fl mice with blood and endothelial cells lacking ERp72 had prolonged tail bleeding times and decreased platelet accumulation in laser-induced cremaster arteriole injury and FeCl3-induced mesenteric arterial injury. ferric chloride 257-262 protein disulfide isomerase associated 4 Mus musculus 133-138 28751543-8 2017 In a mouse model of ferric chloride-induced arterial thrombosis, GPVI-CD39 effectively delayed vascular thrombosis but did not increase tail bleeding time in vivo. ferric chloride 20-35 glycoprotein VI platelet Homo sapiens 65-69 28751543-8 2017 In a mouse model of ferric chloride-induced arterial thrombosis, GPVI-CD39 effectively delayed vascular thrombosis but did not increase tail bleeding time in vivo. ferric chloride 20-35 ectonucleoside triphosphate diphosphohydrolase 1 Homo sapiens 70-74 28530398-1 2017 Three novel pi-extended BF2 complexes of beta,beta-bisphenanthrene-fused azadipyrromethenes containing nine fused rings have been synthesized on the basis of a tandem Suzuki coupling reaction on readily available 2,6-dibromoazaBODIPYs followed by an intramolecular oxidative aromatic coupling mediated by iron(III) chloride. ferric chloride 305-323 forkhead box G1 Homo sapiens 24-27 28539835-0 2017 The Myosin II Inhibitor, Blebbistatin, Ameliorates FeCl3-induced Arterial Thrombosis via the GSK3beta-NF-kappaB Pathway. ferric chloride 51-56 glycogen synthase kinase 3 beta Mus musculus 93-101 28539835-8 2017 The present study demonstrates that blebbistatin may impede TF expression partly via the Akt/GSK3beta-NF-kappaB signalling pathways in the endothelium in a FeCl3 model, shedding new insights into the pathogenesis of arterial thrombosis and providing new clues for the development of antithrombotic drugs. ferric chloride 156-161 coagulation factor III Mus musculus 60-62 28539835-8 2017 The present study demonstrates that blebbistatin may impede TF expression partly via the Akt/GSK3beta-NF-kappaB signalling pathways in the endothelium in a FeCl3 model, shedding new insights into the pathogenesis of arterial thrombosis and providing new clues for the development of antithrombotic drugs. ferric chloride 156-161 thymoma viral proto-oncogene 1 Mus musculus 89-92 28539835-8 2017 The present study demonstrates that blebbistatin may impede TF expression partly via the Akt/GSK3beta-NF-kappaB signalling pathways in the endothelium in a FeCl3 model, shedding new insights into the pathogenesis of arterial thrombosis and providing new clues for the development of antithrombotic drugs. ferric chloride 156-161 glycogen synthase kinase 3 beta Mus musculus 93-101 28336561-7 2017 Interestingly, platelets from LAIR-1-deficient mice exhibit an enhanced reactivity to collagen and the glycoprotein VI-specific agonist collagen-related peptide despite not expressing LAIR-1, and mice showed enhanced thrombus formation in the carotid artery after ferric chloride injury. ferric chloride 264-279 leukocyte-associated Ig-like receptor 1 Mus musculus 30-36 26705390-6 2017 The BDNF Met allele predisposed to carotid artery thrombosis FeCl3-induced and to death after collagen/epinephrine injection. ferric chloride 61-66 brain derived neurotrophic factor Mus musculus 4-8 27022167-7 2017 Thus, a single short-term treatment with a high concentration of FeCl3 in the unilateral middle ear cavity can induce activation of intracellular signals for cJun protein and oxidative stress through the formation of reactive oxygen species and nitric oxide in vestibular sensory receptors, resulting in vestibular dysfunction. ferric chloride 65-70 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 158-162 28238438-4 2017 ARID2 depletion attenuated nucleotide excision repair (NER) of DNA damage sites introduced by exposure to UV as well as chemical compounds known as carcinogens for HCC, benzo[a]pyrene and FeCl3, since xeroderma pigmentosum complementation group G (XPG) could not accumulate without ARID2. ferric chloride 188-193 AT-rich interaction domain 2 Homo sapiens 0-5 28028021-13 2017 Deletion of Ask1 also reduces thrombosis as assessed by delayed vessel occlusion of carotid artery after FeCl3-induced injury and protects against collagen/epinephrine-induced pulmonary thromboembolism. ferric chloride 105-110 mitogen-activated protein kinase kinase kinase 5 Mus musculus 12-16 27560602-9 2017 Furthermore, ATL-2 and ATL-3 diminished the spreading of human platelets on immobilized fibrinogen (Fg), delayed clot retraction in platelet-depleted plasma containing human platelets, extended first occlusion time in a mouse model of ferric chloride (FeCl3)-induced carotid arterial thrombosis, and prolonged the bleeding time. ferric chloride 235-250 atlastin GTPase 2 Homo sapiens 13-18 27560602-9 2017 Furthermore, ATL-2 and ATL-3 diminished the spreading of human platelets on immobilized fibrinogen (Fg), delayed clot retraction in platelet-depleted plasma containing human platelets, extended first occlusion time in a mouse model of ferric chloride (FeCl3)-induced carotid arterial thrombosis, and prolonged the bleeding time. ferric chloride 235-250 atlastin GTPase 3 Homo sapiens 23-28 27560602-9 2017 Furthermore, ATL-2 and ATL-3 diminished the spreading of human platelets on immobilized fibrinogen (Fg), delayed clot retraction in platelet-depleted plasma containing human platelets, extended first occlusion time in a mouse model of ferric chloride (FeCl3)-induced carotid arterial thrombosis, and prolonged the bleeding time. ferric chloride 252-257 atlastin GTPase 2 Homo sapiens 13-18 27560602-9 2017 Furthermore, ATL-2 and ATL-3 diminished the spreading of human platelets on immobilized fibrinogen (Fg), delayed clot retraction in platelet-depleted plasma containing human platelets, extended first occlusion time in a mouse model of ferric chloride (FeCl3)-induced carotid arterial thrombosis, and prolonged the bleeding time. ferric chloride 252-257 atlastin GTPase 3 Homo sapiens 23-28 27764744-8 2017 The highest TOC, chemical oxygen demand (COD), and chromaticity reduction efficiencies, 81%, 82%, and 97%, respectively, were achieved at pH 4 using FeCl3 (5 g L-1) and polyacrylamide (PAM; 0.07 g L-1). ferric chloride 149-154 immunoglobulin kappa variable 1-16 Homo sapiens 160-163 27903531-4 2017 In a FeCl3-induced thrombosis model, we found that compared with wild-type (WT) control and nonhematopoietic DREAM knockout (KO) mice, DREAM KO control and hematopoietic DREAM KO mice showed a significant delay in time to occlusion. ferric chloride 5-10 Kv channel interacting protein 3, calsenilin Mus musculus 135-140 27903531-4 2017 In a FeCl3-induced thrombosis model, we found that compared with wild-type (WT) control and nonhematopoietic DREAM knockout (KO) mice, DREAM KO control and hematopoietic DREAM KO mice showed a significant delay in time to occlusion. ferric chloride 5-10 Kv channel interacting protein 3, calsenilin Mus musculus 135-140 27764744-8 2017 The highest TOC, chemical oxygen demand (COD), and chromaticity reduction efficiencies, 81%, 82%, and 97%, respectively, were achieved at pH 4 using FeCl3 (5 g L-1) and polyacrylamide (PAM; 0.07 g L-1). ferric chloride 149-154 immunoglobulin kappa variable 1-16 Homo sapiens 197-200 27764744-10 2017 The mole ratio of removed COD and Fe(III) (2.4 mol) at 5 g L-1 FeCl3 (pH 4, PAM 0.07 g L-1) was lower than that (3.8 mol) at 3 g L-1 FeCl3 (pH 4, PAM 0.07 g L-1); based on the cost and COD removal efficiency, the latter conditions were the best choice. ferric chloride 63-68 immunoglobulin kappa variable 1-16 Homo sapiens 59-62 27740661-2 2016 The solvothermal reaction of FeCl3 with urea in an ethylene glycol medium yielded a brown colored powder which was characterized employing a wide range of analytical techniques including high resolution powder X-ray diffraction (PXRD), scanning electron microscopy, thermal analysis, X-ray photo electron spectroscopy (XPS), elemental (C, H, N and S) analysis, UV-visible, photoluminescence spectroscopy measurements, BET surface area and pore-size analysis. ferric chloride 29-34 delta/notch like EGF repeat containing Homo sapiens 418-421 27631377-6 2016 GRIP1-/- mice had normal platelet counts, but a prolonged bleeding time and delayed thrombus formation in a FeCl3-induced vessel injury model. ferric chloride 108-113 glutamate receptor interacting protein 1 Mus musculus 0-5 27627652-7 2016 In a FeCl3 induced carotid artery thrombosis model, vessel occlusion in Wdr1-hypomorphic mice was prolonged significantly compared to wild-type mice (9.0 +- 10.5 minutes versus 5.8 +- 12.6 minutes (p = 0.041). ferric chloride 5-10 WD repeat domain 1 Mus musculus 72-76 27417582-6 2016 In response to 5% FeCl3, but not to 10% FeCl3, there was a significant decrease in the time to thrombosis in CD73-null mice compared with wild-type mice. ferric chloride 18-23 5' nucleotidase, ecto Mus musculus 109-113 27559095-5 2016 The most potent of these IgGs, C24 and DEF, inhibited clotting in whole human blood and prevented FeCl3-induced carotid artery occlusion in FXI-deficient mice reconstituted with human FXI and in thread-induced venous thrombosis in rabbits at clinically relevant doses. ferric chloride 98-103 UTP25 small subunit processome component Homo sapiens 39-42 27559095-5 2016 The most potent of these IgGs, C24 and DEF, inhibited clotting in whole human blood and prevented FeCl3-induced carotid artery occlusion in FXI-deficient mice reconstituted with human FXI and in thread-induced venous thrombosis in rabbits at clinically relevant doses. ferric chloride 98-103 coagulation factor XI Homo sapiens 140-143 27064509-3 2016 The addition of CrCl3 to 1-Cr, and FeCl3 to 2-Fe, afforded oxidatively triggered C-C bond formation as rac-2,2"-di(2,6-(i)Pr2C6H3N )2dicyclohexane (EA2) was produced in modest yields. ferric chloride 35-40 Rac family small GTPase 2 Homo sapiens 103-108 27417582-10 2016 FeCl3-induced arterial thrombosis in chimeric mice revealed a significant prolongation in the time to thrombosis in hCD39-Tg reconstituted wild-type mice, but not on wild-type reconstituted hCD39-Tg mice. ferric chloride 0-5 ectonucleoside triphosphate diphosphohydrolase 1 Homo sapiens 116-121 27064509-3 2016 The addition of CrCl3 to 1-Cr, and FeCl3 to 2-Fe, afforded oxidatively triggered C-C bond formation as rac-2,2"-di(2,6-(i)Pr2C6H3N )2dicyclohexane (EA2) was produced in modest yields. ferric chloride 35-40 calcium voltage-gated channel subunit alpha1 A Homo sapiens 148-151 26782808-3 2016 Using thrombelastography, we compared the coagulation kinetic profiles of plasma exposed to 0-10 microM ferric chloride after activation of coagulation with thrombin generated by contact activation of plasma with the plastic sample cup or by exposure to 1 microg/ml of Calloselasma rhodostoma venom (rich in ancrod activity), which causes coagulation via polymerization of alpha chain monomers. ferric chloride 104-119 coagulation factor II, thrombin Homo sapiens 157-165 26611629-1 2016 This study evaluates the efficacy of a sanitary sewage treatment system, proposing post-treatment of the effluent generated by the upflow anaerobic sludge blanket UASB reactor, through a Fenton coagulation/oxidation ((ferric chloride (FC) or ferrous sulfate (FS) and peracetic acid (PAA)), followed by a double filtration system, composed of a gravel ascending drainage filter and a sand descending filter. ferric chloride 218-233 solute carrier family 35 member G1 Homo sapiens 83-87 26391610-5 2016 We show specifically that anti-beta2-glycoprotein I (anti-beta2GPI) antibodies, a subset of aPL, accelerated thrombus formation in C57BL/6 wild-type, but not TLR4-deficient, mice in a ferric chloride-induced carotid artery injury model. ferric chloride 184-199 apolipoprotein H Mus musculus 31-51 26765360-3 2016 15 mg L(-1) of ferric chloride provided the greatest enhancement of approximately 10-fold, using 20% acetic acid combined with 4% formic acid with 30 s ultraviolet irradiation at 200 mL min(-1) Ar/H2 flow rate. ferric chloride 15-30 CD59 molecule (CD59 blood group) Homo sapiens 186-192 26598717-4 2016 In a model of ferric chloride-induced mesenteric arteriolar thrombosis, vessel occlusion times were twice as long in MINK1(-/-) mice as in WT mice. ferric chloride 14-29 misshapen-like kinase 1 (zebrafish) Mus musculus 117-122 26391610-5 2016 We show specifically that anti-beta2-glycoprotein I (anti-beta2GPI) antibodies, a subset of aPL, accelerated thrombus formation in C57BL/6 wild-type, but not TLR4-deficient, mice in a ferric chloride-induced carotid artery injury model. ferric chloride 184-199 apolipoprotein H Mus musculus 58-66 27838691-6 2016 FeCl3 significantly increased NFkappaB p65, 3-nitrotyrosine, CHOP and ICAM-1 expression, and decreased nuclear Nrf2 translocation and induces arterial thrombus formation. ferric chloride 0-5 synaptotagmin 1 Rattus norvegicus 39-42 26840286-2 2016 These monomers were chemically polymerized using FeCl3 as oxidizing agent to give the corresponding oligomers TPO1-5) and they were electrochemically polymerized to obtain the corresponding polymer films deposited onto ITO. ferric chloride 49-54 serine incorporator 5 Homo sapiens 110-116 27838691-6 2016 FeCl3 significantly increased NFkappaB p65, 3-nitrotyrosine, CHOP and ICAM-1 expression, and decreased nuclear Nrf2 translocation and induces arterial thrombus formation. ferric chloride 0-5 DNA-damage inducible transcript 3 Rattus norvegicus 61-65 27838691-6 2016 FeCl3 significantly increased NFkappaB p65, 3-nitrotyrosine, CHOP and ICAM-1 expression, and decreased nuclear Nrf2 translocation and induces arterial thrombus formation. ferric chloride 0-5 intercellular adhesion molecule 1 Rattus norvegicus 70-76 27838691-6 2016 FeCl3 significantly increased NFkappaB p65, 3-nitrotyrosine, CHOP and ICAM-1 expression, and decreased nuclear Nrf2 translocation and induces arterial thrombus formation. ferric chloride 0-5 NFE2 like bZIP transcription factor 2 Rattus norvegicus 111-115 26508731-6 2015 In an FeCl3 injury-induced carotid artery thrombosis model, thrombus growth rate and the time to occlusion were prolonged in Fn-EDA(-/-)Apoe(-/-) mice (P<0.05 versus Apoe(-/-) mice). ferric chloride 6-11 apolipoprotein E Mus musculus 136-140 27386990-0 2016 Effects of FeCl3 addition on the operation of a staged anaerobic fluidized membrane bioreactor (SAF-MBR). ferric chloride 11-16 FAS antisense RNA 1 Homo sapiens 96-99 27386990-2 2016 Total sulfur removal in the SAF-MBR was 42-59% without FeCl(3) addition, but increased to 87-95% with FeCl(3) addition. ferric chloride 55-62 FAS antisense RNA 1 Homo sapiens 28-31 27386990-2 2016 Total sulfur removal in the SAF-MBR was 42-59% without FeCl(3) addition, but increased to 87-95% with FeCl(3) addition. ferric chloride 102-109 FAS antisense RNA 1 Homo sapiens 28-31 26399659-8 2015 Tail bleeding times and times to occlusion in an FeCl3-induced thrombosis model were prolonged in the VPS33B knockout mice. ferric chloride 49-54 vacuolar protein sorting 33B Mus musculus 102-108 26437694-1 2015 We have synthesized a new family of directly-fused bisBODIPY BBP 1 through a key FeCl3-mediated intramolecular oxidative cyclodehydrogenation reaction and its derivatives 2 and 3 from the Knoevenagel reaction. ferric chloride 81-86 transmembrane protein 158 Homo sapiens 61-64 26263882-8 2015 Our results indicated that FeCl3 and MnO2 could be efficient in reducing sediment P release during algal decomposition, with the strongest effect found for FeCl3; large amounts of NO3 (-) were removed from the aquatic ecosystem through denitrification during algal decomposition. ferric chloride 27-32 NBL1, DAN family BMP antagonist Homo sapiens 180-183 26282541-2 2015 Paradoxically, in a FeCl3 injury model, occlusion, but not initiation of thrombus formation, is delayed in GPVI-deficient and GPVI-depleted mice. ferric chloride 20-25 glycoprotein 6 (platelet) Mus musculus 107-111 26390010-8 2015 The antithrombotic activity of prothrombin ASOs was demonstrated in a FeCl3-induced thrombosis mouse model, and as predicted for this target, the doses required for antithrombotic activity were also associated with increased bleeding. ferric chloride 70-75 coagulation factor II Mus musculus 31-42 26405223-6 2015 In the ferric-chloride vasculature injury model, Abcc4 KO mice exhibited markedly impaired thrombus formation. ferric chloride 7-22 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 Mus musculus 49-54 26434364-4 2015 Key elements in these total syntheses include: (1) FeCl3-catalyzed cationic cascade cyclization to construct podocarpane-type skeleton; (2) Mn(III)/Co(II)-catalyzed radical hydroxylation of alkene with high regio-, diastereo-, and chemoselectivities; (3) and a ketal-deprotection/lactone-opening/deprotonation/lactonization cascade. ferric chloride 51-56 mitochondrially encoded cytochrome c oxidase II Homo sapiens 148-153 26418160-7 2015 Because the internal elastic lamina was lacerated in our FeCl3-induced model, we assume that the interaction between CLEC-2 and its ligands in VSMCs induces thrombus formation. ferric chloride 57-62 C-type lectin domain family 1 member B Homo sapiens 117-123 26282541-2 2015 Paradoxically, in a FeCl3 injury model, occlusion, but not initiation of thrombus formation, is delayed in GPVI-deficient and GPVI-depleted mice. ferric chloride 20-25 glycoprotein 6 (platelet) Mus musculus 126-130 26045608-4 2015 COMP deficiency shortened tail-bleeding and clotting time and accelerated ferric-chloride-induced thrombosis in mice. ferric chloride 74-89 cartilage oligomeric matrix protein Mus musculus 0-4 25427855-5 2015 FeCl3-induced arterial thrombosis in carotid and mesenteric artery revealed that the occlusion time was significantly increased in FSAP-/- mice (p< 0.01) and that some FSAP-/- mice did not occlude at all. ferric chloride 0-5 hyaluronic acid binding protein 2 Mus musculus 131-135 25691157-7 2015 To confirm that HRG modulates the contact system, we used DNase, RNase, and antisense oligonucleotides to characterize the FeCl3 model. ferric chloride 123-128 histidine-rich glycoprotein Mus musculus 16-19 25691157-8 2015 Whereas DNase or FVII knockdown had no effect, carotid occlusion was abrogated with RNase or FXII knockdown, confirming that FeCl3-induced thrombosis is triggered by RNA in a FXII-dependent fashion. ferric chloride 125-130 coagulation factor XII (Hageman factor) Mus musculus 93-97 25691157-8 2015 Whereas DNase or FVII knockdown had no effect, carotid occlusion was abrogated with RNase or FXII knockdown, confirming that FeCl3-induced thrombosis is triggered by RNA in a FXII-dependent fashion. ferric chloride 125-130 coagulation factor XII (Hageman factor) Mus musculus 175-179 25845931-6 2015 Neointimal hyperplasia and vascular inflammation in the common carotid artery were significantly curtailed 4 weeks after FeCl3 injury in fat-1 mice (n=6). ferric chloride 121-126 FAT atypical cadherin 1 Mus musculus 137-142 25944668-7 2015 In vivo adhesion after carotis ligation was significantly decreased in platelets lacking SGK1 and occlusive thrombus formation after FeCl3 -induced vascular injury was significantly diminished in sgk1(-/-) mice. ferric chloride 133-138 serum/glucocorticoid regulated kinase 1 Mus musculus 196-200 25860622-1 2015 A novel oxidative C-H/C-H cross-coupling reaction between electron-rich arenes and alkenes is established utilizing FeCl3 as the catalyst and DDQ as the oxidant. ferric chloride 116-121 churchill domain containing 1 Homo sapiens 18-25 25427855-5 2015 FeCl3-induced arterial thrombosis in carotid and mesenteric artery revealed that the occlusion time was significantly increased in FSAP-/- mice (p< 0.01) and that some FSAP-/- mice did not occlude at all. ferric chloride 0-5 hyaluronic acid binding protein 2 Mus musculus 171-175 25550208-3 2015 APPROACH AND RESULTS: Inhibition of extracellular CyPA through a novel specific inhibitor MM284 reduced thrombus after ferric chloride-induced injury in vivo. ferric chloride 119-134 peptidylprolyl isomerase A Mus musculus 50-54 25520375-7 2015 DUSP3-deficient mice were more resistant to collagen- and epinephrine-induced thromboembolism compared with wild-type mice and showed severely impaired thrombus formation on ferric chloride-induced carotid artery injury. ferric chloride 174-189 dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) Mus musculus 0-5 25648746-1 2015 A high-performance N-doped carbon catalyst with a fog-like, fluffy structure was prepared through pyrolyzing a mixture of polyacrylonitrile, melamine and iron chloride. ferric chloride 154-167 zinc finger protein, FOG family member 1 Homo sapiens 50-53 25339356-2 2015 Klkb1(-/-) mice have delayed carotid artery occlusion times on the rose bengal and ferric chloride thrombosis models. ferric chloride 83-98 kallikrein B, plasma 1 Mus musculus 0-5 25266363-13 2014 MIF reduced thrombus formation under arterial flow conditions in vitro and retarded thrombotic occlusion after FeCl3-induced arterial injury in vivo, an effect mediated through CXCR7. ferric chloride 111-116 macrophage migration inhibitory factor (glycosylation-inhibiting factor) Mus musculus 0-3 25591759-6 2015 TSLPR KO mice exhibited defective carotid artery thrombus formation after exposure to FeCl3. ferric chloride 86-91 cytokine receptor-like factor 2 Mus musculus 0-5 25476391-4 2015 This complexing capacity was used to improve the specific detection of EDTA directly on a concrete matrix by doping the solvent spray of DESI with a solution of FeCl3 to selectively create the complex between EDTA and Fe(III). ferric chloride 161-166 desumoylating isopeptidase 2 Homo sapiens 137-141 26202365-7 2015 Reactive oxygen species (ROS) production in cells treated with FeCl3 or thrombopoietin (TPO) was monitored by using the fluorescent probe H2DCFDA. ferric chloride 63-68 thrombopoietin like 1 Rattus norvegicus 88-91 25266363-13 2014 MIF reduced thrombus formation under arterial flow conditions in vitro and retarded thrombotic occlusion after FeCl3-induced arterial injury in vivo, an effect mediated through CXCR7. ferric chloride 111-116 atypical chemokine receptor 3 Mus musculus 177-182 25313303-2 2014 FeCl3 that has rarely been utilized before is introduced not only as a catalyst but also as an efficient transforming agent which converts boron powder into boron chloride (BCl3) vapor in situ. ferric chloride 0-5 BCL3 transcription coactivator Homo sapiens 173-177 25229306-2 2014 In this study, a methoxyazulitripyrrane condensed with a pyrrole dialdehyde in the presence of TFA, followed by oxidation with ferric chloride, to give a tropone-fused carbaporphyrin following a spontaneous demethylation. ferric chloride 127-142 coagulation factor III, tissue factor Homo sapiens 95-98 24093153-8 2014 Consistent with these findings, GPx1/catalase double-deficiency accelerated the thrombotic response in FeCl3-injured carotid arteries. ferric chloride 103-108 glutathione peroxidase 1 Mus musculus 32-36 25244094-8 2014 Consistent with secretion and cargo deficiencies, Stxbp5 KO mice showed dramatic bleeding in the tail transection model and defective hemostasis in the FeCl3-induced carotid injury model. ferric chloride 152-157 syntaxin binding protein 5 (tomosyn) Mus musculus 50-56 24451386-4 2014 Thrombosis after ferric chloride injury was delayed in MR-EC mice compared with controls as well as in wild-type FVB/NRj mice treated with aldosterone (60 mug/kg/d for 21 d). ferric chloride 17-32 nuclear receptor subfamily 3, group C, member 2 Mus musculus 55-57 24233488-8 2014 In vitro thrombus formation at shear rates of 1700 s(-1) and in vivo thrombus formation after FeCl3 injury were significantly blunted in Smpd1(-/-) mice while bleeding time was unaffected. ferric chloride 94-99 sphingomyelin phosphodiesterase 1, acid lysosomal Mus musculus 137-142 24408325-7 2014 fXII-deficient mice are resistant to ferric chloride-induced arterial thrombosis, and this resistance can be reversed by infusion of human fXII. ferric chloride 37-52 coagulation factor XII (Hageman factor) Mus musculus 0-4 24408325-7 2014 fXII-deficient mice are resistant to ferric chloride-induced arterial thrombosis, and this resistance can be reversed by infusion of human fXII. ferric chloride 37-52 coagulation factor XII (Hageman factor) Mus musculus 139-143 24323317-6 2014 METHODS AND RESULTS: Inhibiting in vivo the receptor EP3 for PGE2 with the blocking agent DG-041 reduced murine thrombosis triggered by local delivery of arachidonic acid or ferric chloride on healthy arteries. ferric chloride 174-189 prostaglandin E receptor 3 (subtype EP3) Mus musculus 53-56 24485401-5 2014 METHODS: Both photochemical injury and ferric chloride vascular injury models demonstrated arterial thrombosis formation in ApoE deficient mice. ferric chloride 39-54 apolipoprotein E Mus musculus 124-128 24440583-5 2014 Radiolabeled scFv was incubated with in vitro formed platelet clots and injected into mice with FeCl(3) induced thrombus in the left carotid artery. ferric chloride 96-103 immunglobulin heavy chain variable region Homo sapiens 13-17 24473150-3 2014 In this work, metal salts aluminum chloride, calcium chloride, cupric chloride, ferric chloride, potassium chloride, magnesium chloride and sodium chloride were tested for their ability to inhibit AChE. ferric chloride 80-95 acetylcholinesterase (Cartwright blood group) Homo sapiens 197-201 24940514-0 2014 Interleukin-17A Exacerbates Ferric Chloride-Induced Arterial Thrombosis in Rat Carotid Artery. ferric chloride 28-43 interleukin 17A Rattus norvegicus 0-15 23940756-7 2013 Both pharmacologic inhibition of cathepsin G and its congenital absence prolonged the time for platelet thrombus to form in ferric chloride-injured mouse mesenteric arterioles. ferric chloride 124-139 cathepsin G Mus musculus 33-44 24152424-10 2013 Mice lacking both FIX and FXI were more resistant to ferric chloride-induced carotid artery occlusion than FXI-deficient or FIX-deficient mice. ferric chloride 53-68 coagulation factor XI Mus musculus 26-29 23790832-2 2013 Actomyosin isolated from pork muscle then suspended in 0.1M NaCl at pH 6.2 was oxidatively stressed with 10 muM FeCl3/0.1mM ascorbate/1mM H2O2 for 6 or 12h at 4 C. Protein oxidation was evidenced by the loss of myosin and actin, the concomitant formation of disulphide-cross-linked polymers, and elevated myosin ATPase activity. ferric chloride 112-117 myosin heavy chain 14 Homo sapiens 4-10 24184271-6 2013 Similarly, hemin or FeCl3 treatments resulted in increase in HFE expression by reducing nuclear PARP1 pool via its apoptosis induced cleavage, leading to upregulation of the iron regulatory hormone hepcidin mRNA. ferric chloride 20-25 homeostatic iron regulator Homo sapiens 61-64 24184271-6 2013 Similarly, hemin or FeCl3 treatments resulted in increase in HFE expression by reducing nuclear PARP1 pool via its apoptosis induced cleavage, leading to upregulation of the iron regulatory hormone hepcidin mRNA. ferric chloride 20-25 poly(ADP-ribose) polymerase 1 Homo sapiens 96-101 24184271-6 2013 Similarly, hemin or FeCl3 treatments resulted in increase in HFE expression by reducing nuclear PARP1 pool via its apoptosis induced cleavage, leading to upregulation of the iron regulatory hormone hepcidin mRNA. ferric chloride 20-25 hepcidin antimicrobial peptide Homo sapiens 198-206 23165433-5 2013 Irradiation of the FeCl(3)/H(4)L red DMF solution in the visible region of the spectrum resulted in its complete discoloration and from which the unknown colorless salt [Fe(II)(DMF)(6)][Fe(II)Cl(4)] and the neutral ligand have been identified by single crystal diffraction. ferric chloride 19-26 H4 clustered histone 7 Homo sapiens 27-32 23766558-6 2013 Accordingly, ferric-chloride-induced arteriolar thrombus formation, which was already increased by SHP-1 inhibition, was further enhanced in the setting of TNFalpha -induced inflammation. ferric chloride 13-28 protein tyrosine phosphatase, non-receptor type 6 Mus musculus 99-104 23172304-5 2013 The intravenous administration of rPN2KPI into mice dramatically decreased thrombus formation in a murine model of FeCl(3)-induced carotid injury, whereas rPN2KPI-R(15)K,M(17)K failed to inhibit thrombus formation. ferric chloride 115-122 ribophorin II Rattus norvegicus 34-38 23766558-6 2013 Accordingly, ferric-chloride-induced arteriolar thrombus formation, which was already increased by SHP-1 inhibition, was further enhanced in the setting of TNFalpha -induced inflammation. ferric chloride 13-28 tumor necrosis factor Mus musculus 156-164 22720736-3 2013 GPIbalpha-vWF participation in FeCl(3)-induced thrombus formation was evaluated in the inferior vena cava (IVC). ferric chloride 31-38 glycoprotein 1b, alpha polypeptide Mus musculus 0-9 22720736-3 2013 GPIbalpha-vWF participation in FeCl(3)-induced thrombus formation was evaluated in the inferior vena cava (IVC). ferric chloride 31-38 Von Willebrand factor Mus musculus 10-13 22720736-10 2013 The chimeric protein GPIbalpha(2V)-Fc prevented occlusion, demonstrating that GPIbalpha-vWF A1 domain interaction is required for FeCl(3)-induced stable thrombus formation in the IVC. ferric chloride 130-137 glycoprotein Ib platelet subunit alpha Homo sapiens 21-30 22720736-10 2013 The chimeric protein GPIbalpha(2V)-Fc prevented occlusion, demonstrating that GPIbalpha-vWF A1 domain interaction is required for FeCl(3)-induced stable thrombus formation in the IVC. ferric chloride 130-137 glycoprotein Ib platelet subunit alpha Homo sapiens 78-87 22720736-10 2013 The chimeric protein GPIbalpha(2V)-Fc prevented occlusion, demonstrating that GPIbalpha-vWF A1 domain interaction is required for FeCl(3)-induced stable thrombus formation in the IVC. ferric chloride 130-137 Von Willebrand factor Mus musculus 88-91 22720736-11 2013 Therefore, FeCl(3)-induced stable, occlusive thrombus formation in the IVC is platelet, and apparently GPIbalpha-vWF interaction dependent, despite the large diameter and low venous flow rate in the IVC. ferric chloride 11-18 glycoprotein 1b, alpha polypeptide Mus musculus 103-112 22720736-11 2013 Therefore, FeCl(3)-induced stable, occlusive thrombus formation in the IVC is platelet, and apparently GPIbalpha-vWF interaction dependent, despite the large diameter and low venous flow rate in the IVC. ferric chloride 11-18 Von Willebrand factor Mus musculus 113-116 23079185-5 2012 RESULTS: In wildtype mice, stimulation with TNFalpha significantly accelerated thrombotic vessel occlusion in vivo upon ferric chloride injury. ferric chloride 120-135 tumor necrosis factor Mus musculus 44-52 23178924-5 2013 The thrombogenic potential of acute and extended elevation of circulating FVIII levels was assessed using ferric chloride induced injury of the cremaster arterioles. ferric chloride 106-121 coagulation factor VIII Mus musculus 74-79 22782575-9 2012 We observed that, similar to r-tPA, r-ADAMTS13 can dissolve occlusive thrombi induced by FeCl(3) injury in venules. ferric chloride 89-96 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 Mus musculus 38-46 23082924-0 2012 Timosaponin-BII inhibits the up-regulation of BACE1 induced by ferric chloride in rat retina. ferric chloride 63-78 beta-secretase 1 Rattus norvegicus 46-51 22865892-2 2012 METHODS AND RESULTS: We found that ferric chloride-induced arterial thrombus formation was significantly greater in COX-2 knockout compared with wild-type mice. ferric chloride 35-50 cytochrome c oxidase II, mitochondrial Mus musculus 116-121 22616778-1 2012 An efficient access to 1,1-diarylethylenes of biological interest by coupling functionalized aryl Grignard reagents and 1-arylvinyl halides in the presence of FeCl(3)/CuTC is described. ferric chloride 159-166 cutC copper transporter Homo sapiens 167-171 22588534-9 2012 P2Y1 deletion significantly reduced (p < 0.001) venous thrombus weight by 74 % in 3.5 % FeCl(3) injury compared to P2Y1(+/+) littermates. ferric chloride 91-98 purinergic receptor P2Y, G-protein coupled 1 Mus musculus 0-4 22588534-12 2012 In the more severe 5 % FeCl(3)-induced injury model, thrombus weight significantly (p < 0.001) decreased 68 % in P2Y1(-/-) mice versus P2Y1(+/+) mice, and MRS2500 (2 mg/kg) was also beneficial (54 % decrease, p < 0.01). ferric chloride 23-30 purinergic receptor P2Y, G-protein coupled 1 Mus musculus 116-120 22588534-12 2012 In the more severe 5 % FeCl(3)-induced injury model, thrombus weight significantly (p < 0.001) decreased 68 % in P2Y1(-/-) mice versus P2Y1(+/+) mice, and MRS2500 (2 mg/kg) was also beneficial (54 % decrease, p < 0.01). ferric chloride 23-30 purinergic receptor P2Y, G-protein coupled 1 Mus musculus 138-142 22889519-5 2012 Ferric chloride was also demonstrated to induce aggregation of purified fibrinogen at the same molar concentrations that were used for the generation of hydroxyl radicals. ferric chloride 0-15 fibrinogen beta chain Homo sapiens 72-82 22362759-9 2012 PKCepsilon knockout mice exhibited shorter times to occlusion in an FeCl(3)-induced arterial injury model and shorter bleeding times in tail-bleeding experiments. ferric chloride 68-75 protein kinase C, epsilon Mus musculus 0-10 22401798-7 2012 Genetic deletion of P2X7 signaling attenuates FeCl(3)-induced carotid artery thrombosis in mice, indicating that TF prothrombotic activity is regulated by specific cell signaling pathways in vivo. ferric chloride 46-53 purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus 20-24 22552380-9 2012 Furthermore, using this system, we found that thrombin and clot aging impair the thrombolytic action of rtPA towards FeCl3-produced thrombi. ferric chloride 117-122 coagulation factor II Mus musculus 46-54 22401798-7 2012 Genetic deletion of P2X7 signaling attenuates FeCl(3)-induced carotid artery thrombosis in mice, indicating that TF prothrombotic activity is regulated by specific cell signaling pathways in vivo. ferric chloride 46-53 coagulation factor III Mus musculus 113-115 22156595-3 2012 FeCl(3) treatment resulted in intra-arterial occlusive thrombogenesis within 10 min in wild-type (WT) and C2/factor B-null mice. ferric chloride 0-7 host cell factor C2 Mus musculus 106-115 22450202-0 2012 Boat pressure washing wastewater treatment with calcium oxide and/or ferric chloride. ferric chloride 69-84 ataxin 1 like Homo sapiens 0-4 22156595-4 2012 In contrast, mannose-binding lectin (MBL)-null and MBL-associated serine protease (MASP)-1/-3 knockout (KO) mice had significantly decreased FeCl(3)-induced thrombogenesis. ferric chloride 141-148 mannose-binding lectin (protein C) 2 Mus musculus 13-35 22156595-4 2012 In contrast, mannose-binding lectin (MBL)-null and MBL-associated serine protease (MASP)-1/-3 knockout (KO) mice had significantly decreased FeCl(3)-induced thrombogenesis. ferric chloride 141-148 mannose-binding lectin (protein C) 2 Mus musculus 37-40 22156595-4 2012 In contrast, mannose-binding lectin (MBL)-null and MBL-associated serine protease (MASP)-1/-3 knockout (KO) mice had significantly decreased FeCl(3)-induced thrombogenesis. ferric chloride 141-148 mannan-binding lectin serine peptidase 1 Mus musculus 51-90 22156595-5 2012 Reconstitution with recombinant human (rh) MBL restored FeCl(3)-induced thrombogenesis in MBL-null mice to levels comparable to WT mice, suggesting a significant role of the MBL/MASP complex for in vivo coagulation. ferric chloride 56-63 mannose binding lectin 2 Homo sapiens 43-46 22156595-5 2012 Reconstitution with recombinant human (rh) MBL restored FeCl(3)-induced thrombogenesis in MBL-null mice to levels comparable to WT mice, suggesting a significant role of the MBL/MASP complex for in vivo coagulation. ferric chloride 56-63 mannose binding lectin 2 Homo sapiens 90-93 22156595-5 2012 Reconstitution with recombinant human (rh) MBL restored FeCl(3)-induced thrombogenesis in MBL-null mice to levels comparable to WT mice, suggesting a significant role of the MBL/MASP complex for in vivo coagulation. ferric chloride 56-63 mannose-binding lectin (protein C) 2 Mus musculus 90-93 21821713-9 2011 Importantly, Akt3(-/-) mice showed retardation in FeCl3-induced carotid artery thrombosis in vivo. ferric chloride 50-55 thymoma viral proto-oncogene 3 Mus musculus 13-17 21603885-8 2011 Iron-enriched S. aureus PDF was obtained by adding FeCl(3) to the growth medium for E. coli BL21 (DE3) cells and adding FeCl(3) and catalase to all reagents used for purification. ferric chloride 51-58 peptide deformylase, mitochondrial Homo sapiens 24-27 21603885-8 2011 Iron-enriched S. aureus PDF was obtained by adding FeCl(3) to the growth medium for E. coli BL21 (DE3) cells and adding FeCl(3) and catalase to all reagents used for purification. ferric chloride 120-127 peptide deformylase, mitochondrial Homo sapiens 24-27 21670495-7 2011 In addition, P2rx7-/- mice were protected from TF-dependent FeCl3-induced carotid artery thrombosis. ferric chloride 60-65 purinergic receptor P2X, ligand-gated ion channel, 7 Mus musculus 13-18 21799176-3 2011 METHODS AND RESULTS: Using recombinant proteins and a murine model, we demonstrated that an ADAMTS13 variant truncated after either the eighth thrombospondin type 1 repeat or the spacer domain inhibits ferric chloride-induced arterial thrombosis in ADAMTS13(-/-) mice with efficacy similar to that of full-length ADAMTS13. ferric chloride 202-217 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 Mus musculus 92-100 21670495-7 2011 In addition, P2rx7-/- mice were protected from TF-dependent FeCl3-induced carotid artery thrombosis. ferric chloride 60-65 coagulation factor III Mus musculus 47-49 21436072-6 2011 Heterozygous fII(WT/WE) mice were viable and fertile despite a shift toward an antithrombotic phenotype exemplified by prolonged tail-bleeding times and times-to-occlusion after FeCl3 vessel injury. ferric chloride 178-183 coagulation factor II Mus musculus 13-16 21420414-5 2011 We found that these mice are protected from Ang II-mediated neointima formation following iron chloride-induced vascular injury. ferric chloride 90-103 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus 44-50 21569335-7 2011 After carotid ferric chloride injury, EMILIN2 was abundantly expressed in the thrombus and inhibition of EMILIN2 increased platelet de-aggregation after ADP-stimulated platelet aggregation. ferric chloride 14-29 elastin microfibril interfacer 2 Mus musculus 38-45 21623316-1 2011 FeCl3-mediated oxidative cyclization was successfully used to construct an extended thiophene-pendant pyrene skeleton and synthesize a novel thiophene-fused polycyclic aromatic (THTP-C) with a tetracene core. ferric chloride 0-5 thiamine triphosphatase Homo sapiens 178-182 21569335-7 2011 After carotid ferric chloride injury, EMILIN2 was abundantly expressed in the thrombus and inhibition of EMILIN2 increased platelet de-aggregation after ADP-stimulated platelet aggregation. ferric chloride 14-29 elastin microfibril interfacer 2 Mus musculus 105-112 21605006-4 2011 In a cell-free media containing FeCl(3), LA bound #17 microg of Fe/mg of fiber and increased reactive oxygen species generation #3.5 fold, which was reduced by deferoxamine (DEF) treatment. ferric chloride 32-39 UTP25 small subunit processome component Rattus norvegicus 174-177 21186033-8 2011 The equilibrium isotherm showed that the adsorption of thiocyanate on LDHC was consistent with the Langmuir equation and the saturated adsorption capacity of LDHC for thiocyanate was 98.3 mg/g at 20 C. The regenerated LDHC in FeCl(3) solution can be used repeatedly in adsorption-regeneration cycles. ferric chloride 226-233 lactate dehydrogenase C Homo sapiens 158-162 21497778-0 2011 Intravenous low redox potential saline attenuates FeCl3-induced vascular dysfunction via downregulation of endothelial H2O2, CX3CL1, intercellular adhesion molecule-1, and p53 expression. ferric chloride 50-55 C-X3-C motif chemokine ligand 1 Rattus norvegicus 125-131 21497778-0 2011 Intravenous low redox potential saline attenuates FeCl3-induced vascular dysfunction via downregulation of endothelial H2O2, CX3CL1, intercellular adhesion molecule-1, and p53 expression. ferric chloride 50-55 intercellular adhesion molecule 1 Rattus norvegicus 133-166 21497778-0 2011 Intravenous low redox potential saline attenuates FeCl3-induced vascular dysfunction via downregulation of endothelial H2O2, CX3CL1, intercellular adhesion molecule-1, and p53 expression. ferric chloride 50-55 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 172-175 21497778-8 2011 FeCl(3) stimulation significantly enhanced vascular NADPH oxidase activity, ROS production, as well as CX3CL1, ICAM-1, p53, 3-nitrotyrosine, and 4-hydroxynonenal expression in the damaged arteries. ferric chloride 0-7 C-X3-C motif chemokine ligand 1 Rattus norvegicus 103-109 21497778-8 2011 FeCl(3) stimulation significantly enhanced vascular NADPH oxidase activity, ROS production, as well as CX3CL1, ICAM-1, p53, 3-nitrotyrosine, and 4-hydroxynonenal expression in the damaged arteries. ferric chloride 0-7 intercellular adhesion molecule 1 Rattus norvegicus 111-117 21497778-8 2011 FeCl(3) stimulation significantly enhanced vascular NADPH oxidase activity, ROS production, as well as CX3CL1, ICAM-1, p53, 3-nitrotyrosine, and 4-hydroxynonenal expression in the damaged arteries. ferric chloride 0-7 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 119-122 21158393-2 2011 FeCl(2) and CuCl showed, respectively, almost the same and slightly lower activities compared with FeCl(3) in the tert-butoxylation of N-phenylpyrrolidone (1a), whereas no tert-butoxylated product was obtained by use of Fe(OTf)(3), RuCl(3), or Zr(OTf)(4). ferric chloride 99-106 POU class 5 homeobox 1 Homo sapiens 244-254 21186033-8 2011 The equilibrium isotherm showed that the adsorption of thiocyanate on LDHC was consistent with the Langmuir equation and the saturated adsorption capacity of LDHC for thiocyanate was 98.3 mg/g at 20 C. The regenerated LDHC in FeCl(3) solution can be used repeatedly in adsorption-regeneration cycles. ferric chloride 226-233 lactate dehydrogenase C Homo sapiens 158-162 22016802-9 2011 However, the mice bearing Podxl-null platelets showed a significant retardation in the ferric chloride-induced occlusion of the carotid artery. ferric chloride 87-102 podocalyxin-like Mus musculus 26-31 20558612-5 2010 Moreover, rebleeding was more frequent in AMPKalpha2(-/-) mice, and the FeCl(3)-induced thrombi formed in AMPKalpha2(-/-) mice were unstable. ferric chloride 72-79 protein kinase, AMP-activated, alpha 2 catalytic subunit Mus musculus 106-116 20838746-9 2010 In a mouse model of arterial thrombosis, FeCl3-induced thrombus formation markedly enhanced lymphocyte adhesion and infiltration into platelet thrombi, which was abolished by GPIIb/IIIa inhibition. ferric chloride 41-46 integrin alpha 2b Mus musculus 175-180 20930120-4 2010 Par3(-/-) mice showed nearly complete protection against carotid artery thrombosis caused by low FeCl(3) injury. ferric chloride 97-104 pulmonary adenoma resistance 3 Mus musculus 0-4 20516367-9 2010 However, TFPI(Tie2) mice but not TFPI(LysM) mice had increased ferric chloride-induced arterial thrombosis. ferric chloride 63-78 tissue factor pathway inhibitor Mus musculus 9-13 20451958-5 2010 RESULTS: In comparison to control Apoe-/- mice exposed to filtered ambient air, smoke-exposed Apoe-/- mice displayed a 1.8+-0.3 fold enhanced ADP-induced fibrinogen binding ex vivo (P<0.001) and had a shorter time to thrombotic occlusion following ferric chloride injury of the carotid artery (median time to thrombosis of 8 vs. 13 min; P=0.015). ferric chloride 251-266 apolipoprotein E Mus musculus 94-98 20516367-9 2010 However, TFPI(Tie2) mice but not TFPI(LysM) mice had increased ferric chloride-induced arterial thrombosis. ferric chloride 63-78 TEK receptor tyrosine kinase Mus musculus 14-18 20345096-4 2010 An iron-binding assay showed that the rLF retained iron-binding activity and the binding capacity of 1 mg/mL rLF would be saturated by 100 microM of FeCl(3). ferric chloride 149-156 RLF zinc finger Rattus norvegicus 38-41 20583061-1 2010 FeCl(3)6 H(2)O- and FeBr(3)-catalyzed Prins cyclization/halogenation of alkynyl aldehyde acetals has been realized with acetyl chloride or bromide as halogen source in dichloromethane to afford 2-(1-halobenzylidene or alkylidene)-substituted five-membered carbo- and heterocycles, and thus provides an alternative route for vinylic C-Cl and C-Br bond formation. ferric chloride 0-14 carbonyl reductase 1 Homo sapiens 341-345 20700597-8 2010 Differences were found between B6 and A/J mice in vessel wall architecture and EMILIN2 protein in plasma, carotid vessel wall, and thrombi formed after ferric chloride injury. ferric chloride 152-167 elastin microfibril interfacer 2 Mus musculus 79-86 20432077-0 2010 An ellipsometry study on the effect of aluminium chloride and ferric chloride formulations on mucin layers adsorbed at hydrophobic surfaces. ferric chloride 62-77 LOC100508689 Homo sapiens 94-99 20371742-7 2010 Ferric chloride-induced injury to cremaster arterioles showed a marked reduction in thrombus development and platelet adhesion in the presence of circulating 2B VWF. ferric chloride 0-15 Von Willebrand factor Mus musculus 161-164 20400514-9 2010 When Cbl-b(-/-) mice were tested in the ferric chloride thrombosis model, occlusion time was increased and clot stability was reduced compared with wild type controls. ferric chloride 40-55 Casitas B-lineage lymphoma b Mus musculus 5-10 20446705-0 2010 FeCl3-catalyzed oxidative allylation of sp2 and sp3 C-H bond adjacent to a nitrogen atom: easy access to homoallyl tertiary amines. ferric chloride 0-5 Sp2 transcription factor Homo sapiens 40-43 20446705-0 2010 FeCl3-catalyzed oxidative allylation of sp2 and sp3 C-H bond adjacent to a nitrogen atom: easy access to homoallyl tertiary amines. ferric chloride 0-5 Sp3 transcription factor Homo sapiens 48-51 20345096-4 2010 An iron-binding assay showed that the rLF retained iron-binding activity and the binding capacity of 1 mg/mL rLF would be saturated by 100 microM of FeCl(3). ferric chloride 149-156 RLF zinc finger Rattus norvegicus 109-112 20401791-9 2010 Treatment of GFBS- or GFBS + FeCl(3)-exposed HUVEC with AE at 100 or 250 microg significantly decreased the level of LPO and returned the levels of antioxidants cytochrome c reductase and GST to near normal in a dose-dependent manner. ferric chloride 29-36 glutathione S-transferase kappa 1 Homo sapiens 188-191 20139097-7 2010 In vivo, lack of Cdc42 resulted in faster occlusion of ferric chloride-injured arterioles. ferric chloride 55-70 cell division cycle 42 Mus musculus 17-22 20038804-5 2010 Using FeCl3- or laser-induced injury and in vivo imaging that enabled observation of single platelet behavior and the multiple steps in thrombus formation, we determined that Lnk is an essential contributor to the stabilization of developing thrombi within vessels. ferric chloride 6-11 SH2B adaptor protein 3 Mus musculus 175-178 20065293-5 2010 In vivo studies showed that these mice have a normal bleeding time and are not protected from acute pulmonary thromboembolism but are resistant to thrombosis after FeCl(3) injury of the carotid, suggesting that PI3Kbeta is a potential target for antithrombotic drugs. ferric chloride 164-171 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Mus musculus 211-219 19357295-5 2009 These COX-2 knockdown mice displayed an increased propensity for thrombogenesis compared with their wild-type (COX-2(+/+)) littermates observed by intravital microscopy in cremaster muscle arterioles upon ferric chloride challenge. ferric chloride 205-220 prostaglandin-endoperoxide synthase 2 Mus musculus 6-11 19745198-5 2009 FeCl(3)-induced thrombosis was suppressed in the carotid arteries of IRAP(-/-) mice when compared with WT mice. ferric chloride 0-7 leucyl/cystinyl aminopeptidase Mus musculus 69-73 19572598-1 2009 When treated with Ac2O at rt in the presence of 4-6 mol % FeCl3, 2-alkylcinnamaldehydes are converted to 2-alkyl-1H-inden-1-yl acetates through the intermediacy of gem-diacetates. ferric chloride 58-63 adenylate cyclase 2 Homo sapiens 18-21 19740096-2 2009 METHODS AND RESULTS: Using intravital microscopy and ferric chloride (FeCl(3)) injury of mesenteric arterioles, we found that thrombi formed in CD151(+/-) and CD151(-/-) mice were smaller and less stable, than those formed in CD151(+/+) mice, with a tendency for embolization. ferric chloride 53-68 CD151 antigen Mus musculus 144-149 19740096-3 2009 Similarly, in Folt"s FeCl(3)-induced carotid injury model, both CD151(+/-) and CD151(-/-) mice showed more prolonged times to 95% vessel occlusion than CD151(+/+) mice. ferric chloride 21-28 CD151 antigen Mus musculus 64-69 19740096-3 2009 Similarly, in Folt"s FeCl(3)-induced carotid injury model, both CD151(+/-) and CD151(-/-) mice showed more prolonged times to 95% vessel occlusion than CD151(+/+) mice. ferric chloride 21-28 CD151 antigen Mus musculus 79-84 19740096-3 2009 Similarly, in Folt"s FeCl(3)-induced carotid injury model, both CD151(+/-) and CD151(-/-) mice showed more prolonged times to 95% vessel occlusion than CD151(+/+) mice. ferric chloride 21-28 CD151 antigen Mus musculus 79-84 19494325-5 2009 Furthermore, LPS-potentiated thrombin- and collagen-induced platelet aggregation and FeCl(3)-induced thrombus formation were abolished in MyD88 knockout mice. ferric chloride 85-92 myeloid differentiation primary response gene 88 Mus musculus 138-143 19109562-6 2009 Both in vivo thrombus formation in ferric chloride-injured arterioles and thrombocytopenia induced by collagen plus epinephrine challenge were more dramatic in Adamts13(S/S) than in Adamts13(L/L) but less than in Adamts13(-/-). ferric chloride 35-50 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 Mus musculus 160-168 19109562-6 2009 Both in vivo thrombus formation in ferric chloride-injured arterioles and thrombocytopenia induced by collagen plus epinephrine challenge were more dramatic in Adamts13(S/S) than in Adamts13(L/L) but less than in Adamts13(-/-). ferric chloride 35-50 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 Mus musculus 182-190 19109562-6 2009 Both in vivo thrombus formation in ferric chloride-injured arterioles and thrombocytopenia induced by collagen plus epinephrine challenge were more dramatic in Adamts13(S/S) than in Adamts13(L/L) but less than in Adamts13(-/-). ferric chloride 35-50 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 Mus musculus 182-190 19164598-8 2009 Finally, PKC-theta(-/-) mice displayed unstable thrombus formation and prolonged arterial occlusion in the FeCl(3) in vivo thrombosis model compared with wild-type mice. ferric chloride 107-114 protein kinase C, theta Mus musculus 9-18 19213940-10 2009 In a FeCl3-induced injury in vivo thrombosis model, PKCdelta-/- mice occluded similar to their wild-type littermates. ferric chloride 5-10 protein kinase C, delta Mus musculus 52-60 19192108-10 2009 CONCLUSIONS: In summary, the presence of circulating anti-HSP60 autoantibodies resulted in increased P-selectin and VWF expression and altered cell morphology in endothelial cells lining uninjured carotid arteries, and promoted thrombosis and inflammatory cell recruitment in FeCl3-injured carotid arteries. ferric chloride 276-281 heat shock protein 1 (chaperonin) Mus musculus 58-63 18957966-6 2009 Moreover, the mice expressing both ADAMTS13 and MDTCS showed a significant prolongation of ferric chloride-induced carotid arterial occlusion time as compared to the Adamts13(-/-) expressing eGFP. ferric chloride 91-106 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 Mus musculus 35-43 19141866-6 2009 The levels of plasma ADAMTS13 were sufficient to eliminate the ultralarge VWF multimers and offered systemic protection against ferric chloride-induced arterial thrombosis. ferric chloride 128-143 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 Mus musculus 21-29 18931346-0 2009 Vascular smooth muscle-derived tissue factor is critical for arterial thrombosis after ferric chloride-induced injury. ferric chloride 87-102 coagulation factor III Mus musculus 31-44 18931346-7 2009 Thrombus-mediated flow reduction in response to ferric chloride injury of the carotid arteries was significantly attenuated in VSMC-specific TF-deficient. ferric chloride 48-63 coagulation factor III Mus musculus 141-143 19008452-7 2009 Furthermore, using intravital microscopy to ferric chloride-injured mesenteric arterioles, we show that thrombi formed in vivo in ceacam1(-/-) mice were larger and were more stable than those in wild-type mice. ferric chloride 44-59 carcinoembryonic antigen-related cell adhesion molecule 1 Mus musculus 130-137 18448153-8 2008 RESULTS: Dose-dependent analysis demonstrated that 2 mg/kg, i.p., LPS provided a maximal prothrombotic effect in 2.5% ferric chloride-induced vena cava thrombosis, with a 60% increase in thrombus size (n=8, p<0.05) compared to vehicle treatment. ferric chloride 118-133 toll-like receptor 4 Mus musculus 66-69 18556568-6 2008 Importantly, transgene encoded plasma vWF restored proper platelet adhesion and aggregation in a FeCl(3) induced thrombosis model. ferric chloride 97-104 Von Willebrand factor Mus musculus 38-41 18642814-2 2008 The oxidation of alkanes by various peroxides ((t)BuOOH, H2O2, PhCH2C(CH3)2OOH) is efficiently catalyzed by [Os(VI)(N)Cl4](-)/Lewis acid (FeCl3 or Sc(OTf)3) in CH2Cl2/CH3CO2H to give alcohols and ketones. ferric chloride 138-143 POU class 5 homeobox 1 Homo sapiens 147-155 18094327-10 2008 SG-/- mice exhibited reduced carotid artery thrombus formation after exposure to FeCl3. ferric chloride 81-86 serglycin Mus musculus 0-2 17991876-5 2008 Using a flow chamber and the ferric-chloride injury model we found that EDA+ FN accelerates thrombosis both in vitro and in vivo at arterial shear rates. ferric chloride 29-44 ectodysplasin-A Mus musculus 72-75 17991876-5 2008 Using a flow chamber and the ferric-chloride injury model we found that EDA+ FN accelerates thrombosis both in vitro and in vivo at arterial shear rates. ferric chloride 29-44 fibronectin 1 Mus musculus 77-79 18254395-4 2008 It was observed that ferric chloride provides the best PCB removal efficiency from the extract. ferric chloride 21-36 pyruvate carboxylase Homo sapiens 55-58 18448153-10 2008 A similar prothrombotic effect was observed for LPS in 2.5% FeCl(3)-induced carotid arterial thrombosis model. ferric chloride 60-67 toll-like receptor 4 Mus musculus 48-51 17598016-3 2007 In ferric chloride-induced carotid artery lesions in chow-fed mice, uPA deficiency increased neointimal size (P = 0.015) and luminal stenosis (P = 0.014), while reducing media thickness (P = 0.002). ferric chloride 3-18 plasminogen activator, urokinase Mus musculus 68-71 18375638-4 2007 Topical administration of FeCl(3) (5 microL; 100 mM) into the sensorimotor cortex of rats showed an increase in the wet dog shake behavior, spike wave discharges together with an significant increase in antioxidant enzyme activity, such as superoxide dismutase and catalase, resulting in an increase in the level of lipid peroxidation in cerebral cortex. ferric chloride 26-33 catalase Canis lupus familiaris 265-273 17955138-3 2007 Oxidative coupling by FeCl(3) of the [nido-7,8-C(2)B(9)H(11)-9-Me](-) anion 1a with SMe(2) yields a mixture of four isomers of 9-(SMe(2))-nido-7,8-C(2)B(9)H(10)-X-Me, where X = 1, 2, 3 and 4 (compounds 2a, 2b, 2c and 2d respectively). ferric chloride 22-29 xenotropic and polytropic retrovirus receptor 1 Homo sapiens 173-190 17644153-7 2007 For FeCl(3), pre-ozonation acts as a coagulation aid at low dosage (1.0 mg L(-1) O(3)) for turbidity and UV(254) removal; while at higher dosage (2.0 mg L(-1) O(3)), pre-ozonation is detrimental to UV(254) removal although it is still beneficial for turbidity removal. ferric chloride 4-11 immunoglobulin kappa variable 1-16 Homo sapiens 75-85 17644153-7 2007 For FeCl(3), pre-ozonation acts as a coagulation aid at low dosage (1.0 mg L(-1) O(3)) for turbidity and UV(254) removal; while at higher dosage (2.0 mg L(-1) O(3)), pre-ozonation is detrimental to UV(254) removal although it is still beneficial for turbidity removal. ferric chloride 4-11 immunoglobulin kappa variable 1-16 Homo sapiens 153-163 17579181-5 2007 HS1-null mice displayed increased bleeding times and increased time to occlusion in the FeCl(3) in vivo thrombosis model compared with their wild-type littermates. ferric chloride 88-95 hematopoietic cell specific Lyn substrate 1 Mus musculus 0-3 17576811-6 2007 Further evaluation of mutant mice by the ferric chloride-induced arterial injury model suggests that the Capn1-/- mice are relatively resistant to thrombosis in vivo. ferric chloride 41-56 calpain 1 Mus musculus 105-110 16959404-6 2007 Percentage removals of 73, 95 and 97 for COD, TP and TSS, respectively, were achieved by the addition of 300mg/L FeCl(3).6H(2)O, whereas 91, 99 and 97% removal of COD, TP and TSS, respectively, were achieved with the addition of 25mg/L polyelectrolyte to 100mg/L ferric chloride. ferric chloride 263-278 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 41-44 17408599-0 2007 Effect of levetiracetam on molecular regulation of hippocampal glutamate and GABA transporters in rats with chronic seizures induced by amygdalar FeCl3 injection. ferric chloride 146-151 solute carrier family 1 member 3 Rattus norvegicus 63-94 17111204-0 2007 Deficiency in thrombin-activatable fibrinolysis inhibitor (TAFI) protected mice from ferric chloride-induced vena cava thrombosis. ferric chloride 85-100 carboxypeptidase B2 (plasma) Mus musculus 14-57 17119108-4 2007 Using gene-targeted mice, we show that in ferric chloride-injured veins platelet adhesion to subendothelium is decreased and thrombus growth is impaired in VWF(-/-) mice when compared with wild type (WT). ferric chloride 42-57 Von Willebrand factor Mus musculus 156-159 16507775-9 2006 In a model of FeCl(3)-induced injury in mesenteric arterioles, alpha(2A)(-/-) mice displayed a 2-fold increase in embolus formation, suggesting thrombus instability. ferric chloride 14-21 adrenergic receptor, alpha 2a Mus musculus 63-71 17075060-4 2006 Platelet adhesion to ferric chloride-treated mesenteric arterioles in IL4Ralpha/GPIbalpha-tg mice was virtually absent in contrast to avid adhesion in WT mice. ferric chloride 21-36 interleukin 4 receptor, alpha Mus musculus 70-79 17075060-4 2006 Platelet adhesion to ferric chloride-treated mesenteric arterioles in IL4Ralpha/GPIbalpha-tg mice was virtually absent in contrast to avid adhesion in WT mice. ferric chloride 21-36 glycoprotein 1b, alpha polypeptide Mus musculus 80-89 16386895-3 2007 Results indicated that ferric chloride was superior to the other coagulants and removed 94% of colour at an optimum dose of 800 mg/l at pH 4. ferric chloride 23-38 prolyl 4-hydroxylase, transmembrane Homo sapiens 136-140 16788103-7 2006 The requirement for Btk and TxA2 receptor function in GPIb-dependent arterial thrombosis was confirmed in vivo by characterizing blood flow in ferric chloride-treated mouse carotid arteries. ferric chloride 143-158 Bruton agammaglobulinemia tyrosine kinase Mus musculus 20-23 16788103-7 2006 The requirement for Btk and TxA2 receptor function in GPIb-dependent arterial thrombosis was confirmed in vivo by characterizing blood flow in ferric chloride-treated mouse carotid arteries. ferric chloride 143-158 thromboxane A2 receptor Mus musculus 28-41 15837262-10 2005 FeCl(3) application increased in vivo expressions of platelet P-selectin in P(+/+) mice but not in P(-/-) mice. ferric chloride 0-7 selectin, platelet Mus musculus 62-72 16140263-4 2005 Oxidation of LDL by the O2/cytochrome P450 cytochrome c reductase/NADPH/FeCl3 MFO system is only slightly higher (25%) in the bicarbonate/CO2 buffer as compared to phosphate buffer, but is dependent on all components except FeCl3. ferric chloride 72-77 cytochrome c, somatic Homo sapiens 43-55 16140263-4 2005 Oxidation of LDL by the O2/cytochrome P450 cytochrome c reductase/NADPH/FeCl3 MFO system is only slightly higher (25%) in the bicarbonate/CO2 buffer as compared to phosphate buffer, but is dependent on all components except FeCl3. ferric chloride 224-229 cytochrome c, somatic Homo sapiens 43-55 16129039-8 2005 Surprisingly, when cells treated with FeCl(3), there was not decline of TfR mRNA expression, but it increased lightly at 12 hours and peaked at 24 hours and declined drastically at 48 hours. ferric chloride 38-45 transferrin receptor Homo sapiens 72-75 16455953-7 2006 These data indicate a significant role for GPVI in FeCl(3)-induced thrombus formation. ferric chloride 51-58 glycoprotein 6 (platelet) Mus musculus 43-47 16506510-3 2006 The results showed that the values of concentrations found in supernatants obtained after settling of the flocs for two of the dependent variables studied, filtrate chemical oxygen demand (CODf) and total organic carbon (TOC), were significantly influenced by both the FeCl3 and MCP1 doses at an error lower than 5%. ferric chloride 269-274 C-C motif chemokine ligand 2 Homo sapiens 279-283 16274841-4 2005 CLB treatment was associated with an increase in the production of GLT-1 in the contra-lateral hippocampus of animals receiving amygdalar FeCl(3) and CLB treatment. ferric chloride 138-145 solute carrier family 1 member 2 Rattus norvegicus 67-72 16254207-6 2005 The physiological importance of this GPVI pathway was shown in a FeCl3-induced in vivo murine thrombosis model. ferric chloride 65-70 glycoprotein 6 (platelet) Mus musculus 37-41 16125204-5 2005 The increase of MGST1 activity by gallic acid was prevented by co-incubation with a stable radical, 1,1-diphenyl-2-picrylhydrazyl or ferric chloride. ferric chloride 133-148 microsomal glutathione S-transferase 1 Rattus norvegicus 16-21 15733058-2 2005 The purpose of this work was to evaluate FXI and FIX as potential therapeutic targets by means of a refined ferric chloride (FeCl(3))-induced arterial injury model in factor-deficient mice. ferric chloride 108-123 coagulation factor XI Mus musculus 41-44 15625672-3 2005 The experimental conditioner was an aqueous solution of 10% ascorbic acid and 5% ferric chloride (Exp). ferric chloride 81-96 muscleblind like splicing regulator 1 Homo sapiens 98-101 15733058-2 2005 The purpose of this work was to evaluate FXI and FIX as potential therapeutic targets by means of a refined ferric chloride (FeCl(3))-induced arterial injury model in factor-deficient mice. ferric chloride 125-132 coagulation factor XI Mus musculus 41-44 15733058-5 2005 In contrast, FXI- and FIX-deficient mice were fully protected from occlusion induced by 5% FeCl(3), and were partially protected against the effect of 7.5% FeCl(3). ferric chloride 91-97 coagulation factor XI Mus musculus 13-16 15608608-8 2004 RESULTS: The EW/Oil animals had enhanced endogenous and FeCl(3)-stimulated TBARS levels in the cerebellum and the hippocampus in a manner potentiated by bicuculline but inhibited by E2. ferric chloride 56-63 dihydrolipoamide S-succinyltransferase Rattus norvegicus 182-184 15624963-1 2005 The Diels-Alder reaction of 1,2-dimethylene[2.n]MCPs (MCP = metacyclophane) with suitable dienophiles followed by aromatization and photoinduced or FeCl(3)-induced transannular cyclization afforded phenanthrene-anellated polycyclic aromatic hydrocarbons, which were found to adopt helical chirality in the solid state. ferric chloride 148-155 CD46 molecule Homo sapiens 48-51 15535719-1 2004 Although the ion [Os(VIII)(N)(O)(3)](-) is a stable species and is not known to act as an oxidant for organic substrates, it is readily activated by FeCl(3) in CH(2)Cl(2)/CH(3)CO(2)H to oxidize alkanes efficiently at room temperature. ferric chloride 149-156 cytochrome c oxidase subunit 8A Homo sapiens 21-25 15358667-6 2004 Time to carotid artery occlusion after ferric chloride (FeCl3) was significantly reduced by 20% in cd73-/- mice (P<0.05). ferric chloride 39-54 5' nucleotidase, ecto Mus musculus 99-103 15358667-6 2004 Time to carotid artery occlusion after ferric chloride (FeCl3) was significantly reduced by 20% in cd73-/- mice (P<0.05). ferric chloride 56-61 5' nucleotidase, ecto Mus musculus 99-103 15351845-12 2004 Taken together, these data indicated that local VSMC-specific TFPI overexpression attenuated ferric chloride-induced thrombosis without systemic or hemostatic effects. ferric chloride 93-108 tissue factor pathway inhibitor Mus musculus 62-66 15039280-3 2004 Thus, activated mouse prothrombin R157A/R268A is similar to human meizothrombin in activity toward S-2238, fibrinogen, and protein C. The time to occlusion after FeCl(3)-induced carotid artery injury was delayed (11.8 +/- 3.6 minutes, n = 5) in Cf2(+/-) mice infused with prothrombin R157A/R268A compared with control mice infused with wild-type prothrombin (5.3 +/- 1.5 minutes, n = 3; P =.006). ferric chloride 162-169 coagulation factor II Mus musculus 22-33 14512369-2 2003 METHODS AND RESULTS: We used the ferric chloride model to induce carotid artery injury in apolipoprotein E knockout (apoE-/-) and wild-type (WT) mice. ferric chloride 33-48 apolipoprotein E Mus musculus 90-106 15239708-3 2004 The modified reagent (tentatively designated as the KMT reagent) was composed of 50 mmol l(-1) EDTA-2Na, 50 mmol l(-1) ferric chloride hexahydrate (FeCl(3).6H(2)O), 50 mmol l(-1) potassium iodide (KI) and 50% ethanol in 0.85% NaCl solution at pH 0.3. ferric chloride 119-146 calmodulin-lysine N-methyltransferase Homo sapiens 52-55 15081765-8 2004 Comparative evaluation of As(III) and As(V) removal by chemical coagulation (with ferric chloride) and electrocoagulation has been done. ferric chloride 82-97 SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens 38-43 15161023-4 2004 The cytotoxic activity of HK1 against HL-60 and HSC-2 cells was reduced in the presence of FeCl3, while that of HK3 was significantly increased by FeCl3. ferric chloride 91-96 hexokinase 1 Homo sapiens 26-29 15161023-4 2004 The cytotoxic activity of HK1 against HL-60 and HSC-2 cells was reduced in the presence of FeCl3, while that of HK3 was significantly increased by FeCl3. ferric chloride 147-152 hexokinase 1 Homo sapiens 26-29 15161023-4 2004 The cytotoxic activity of HK1 against HL-60 and HSC-2 cells was reduced in the presence of FeCl3, while that of HK3 was significantly increased by FeCl3. ferric chloride 147-152 hexokinase 3 Homo sapiens 112-115 15161023-9 2004 On the other hand, HK3 did not activate the caspase 3, 8 and 9 in HL-60 cells, but activated the caspase 3 only slightly in the presence of FeCl3. ferric chloride 140-145 hexokinase 3 Homo sapiens 19-22 15648447-3 2004 The time to thrombotic occlusion induced by FeCl3 in p38alpha+/- mice was prolonged compared to that in wild-type (WT) mice. ferric chloride 44-49 mitogen-activated protein kinase 14 Mus musculus 53-61 14594285-1 2003 A new strategy which uses very cheap FeCl3 as an effective catalyst in the presence of Me3SiCl has been developed for the conjugate addition of enones and chalcone with unactivated weakly nucleophilic carbamates. ferric chloride 37-42 malic enzyme 3 Homo sapiens 87-90 12431073-2 2002 This reaction, which is contingent upon the use of Lewis acid, can be conducted with a range of metal salts (Yb(OTf)3, AlCl3, Sn(OTf)2, Cu(OTf)2, MgBr2.Et2O, FeCl3, Zn(OTf)2) with catalyst loadings as low as 5 mol %. ferric chloride 158-163 POU class 2 homeobox 2 Homo sapiens 139-144 12444762-0 2002 Analysis of problematic complexing behavior of ferric chloride with N,N-dimethylformamide using combined techniques of FT-IR, XPS, and TGA/DTG. ferric chloride 47-62 T-box transcription factor 1 Homo sapiens 135-138 12444762-2 2002 From the compositional and structural analyses for the adduct of FeCl(3)/DMF using various techniques such as FTIR, elemental analysis, UV/vis, XPS, and TGA/DTG, it was found that the iron cation exists in the form of an Fe(3+) cation and coordinates via the carbonyl oxygen atom of amide bond in DMF. ferric chloride 65-72 T-box transcription factor 1 Homo sapiens 153-156 12878326-6 2003 The induction of lipid peroxidation due to the block in SeP protein expression or treatment with ferric chloride (FeCl(3)) up-regulated the expression levels of TNF-alpha mRNA and protein. ferric chloride 97-112 tumor necrosis factor Homo sapiens 161-170 12878326-6 2003 The induction of lipid peroxidation due to the block in SeP protein expression or treatment with ferric chloride (FeCl(3)) up-regulated the expression levels of TNF-alpha mRNA and protein. ferric chloride 114-121 tumor necrosis factor Homo sapiens 161-170 12132915-6 2002 The Fe(III) species Dipp(2)N(wedge)NFeCl(2), 6, was obtained cleanly from the reaction of FeCl(3) with Dipp(2)N(wedge)NLi. ferric chloride 90-97 nudix hydrolase 3 Homo sapiens 20-24 12384423-1 2002 The recent observation that knock-out of protease-activated receptor-4 (PAR4) ablates thrombin signaling in mouse platelets and protects against ferric chloride-induced thrombosis of mouse mesenteric arterioles suggests that thrombin"s actions on platelets can play an important role in thrombosis. ferric chloride 145-160 coagulation factor II (thrombin) receptor-like 3 Mus musculus 41-70 12384423-1 2002 The recent observation that knock-out of protease-activated receptor-4 (PAR4) ablates thrombin signaling in mouse platelets and protects against ferric chloride-induced thrombosis of mouse mesenteric arterioles suggests that thrombin"s actions on platelets can play an important role in thrombosis. ferric chloride 145-160 coagulation factor II (thrombin) receptor-like 3 Mus musculus 72-76 12384423-5 2002 We now report that Par3(-/-) mice were protected against ferric chloride-induced thrombosis of mesenteric arterioles and against thromboplastin-induced pulmonary embolism. ferric chloride 57-72 pulmonary adenoma resistance 3 Mus musculus 19-23 12529982-4 2002 The apoptosis, caused by deferoxamine mesylate, and gallium or indium bound to transferrin in the MCF-7 cells, can be completely inhibited by excess ferric chloride or equimolar iron-loaded transferrin. ferric chloride 149-164 transferrin Homo sapiens 79-90 12529982-6 2002 Deferoxamine mesylate induced a small increase in the endogenous expression of both the bcl-2 and bax genes in the MCF-7 cells and this can be prevented by ferric chloride. ferric chloride 156-171 BCL2 apoptosis regulator Homo sapiens 88-93 12529982-6 2002 Deferoxamine mesylate induced a small increase in the endogenous expression of both the bcl-2 and bax genes in the MCF-7 cells and this can be prevented by ferric chloride. ferric chloride 156-171 BCL2 associated X, apoptosis regulator Homo sapiens 98-101 12132915-6 2002 The Fe(III) species Dipp(2)N(wedge)NFeCl(2), 6, was obtained cleanly from the reaction of FeCl(3) with Dipp(2)N(wedge)NLi. ferric chloride 90-97 nudix hydrolase 3 Homo sapiens 103-107 12014960-2 2002 The correlations between the results of enzyme inhibition, ferric chloride tests, and the conformational analysis suggested that the tight binding between triketone-type inhibitors and 4-HPPD is likely due to chelation of the enzyme-bound ferric iron with the enol tautomer of 1,3-diketone moiety of the triketones. ferric chloride 59-74 4-hydroxyphenylpyruvate dioxygenase Homo sapiens 185-191 11425776-4 2001 METHODS AND RESULTS: Ferric chloride injury of the midportion of the common carotid arteries of apoE(-/-) mice (n=22) induced formation of a neointima that contained smooth muscle cells, foam cells, neutral lipid, tissue factor, and von Willebrand factor. ferric chloride 21-36 apolipoprotein E Mus musculus 96-100 12008966-0 2002 FXI is essential for thrombus formation following FeCl3-induced injury of the carotid artery in the mouse. ferric chloride 50-55 coagulation factor XI Mus musculus 0-3 11795261-3 2001 We found that leptin-deficient ob/ob mice had prolonged times to thrombosis after arterial injury with ferric chloride and that exogenously administered leptin corrected their phenotype in a dose-dependent manner. ferric chloride 103-118 leptin Mus musculus 14-20 11978060-6 2002 Addition of unhindered iron, in the form of iron chloride, to the treated-explants reversed the stimulatory effect on EVT outgrowth and HIF-1alpha expression. ferric chloride 44-57 hypoxia inducible factor 1 subunit alpha Homo sapiens 136-146 11767098-4 2001 In order to inhibit the binding of 67Ga to transferrin in the blood, FeCl3 was administered 5 min before the injection of 67Ga. ferric chloride 69-74 transferrin Rattus norvegicus 43-54 11767098-5 2001 The administration of FeCl3 decreased the uptake of 67Ga by the liver of the partially hepatectomized rats, suggesting that transferrin is involved in the uptake by the liver. ferric chloride 22-27 transferrin Rattus norvegicus 124-135 11435305-2 2001 Using an intravital microscopy mouse model, it was previously established that vWF plays a critical role in mediating platelet adhesion and thrombus formation following mesenteric arteriolar injury induced by ferric chloride. ferric chloride 209-224 Von Willebrand factor Mus musculus 79-82 11425776-4 2001 METHODS AND RESULTS: Ferric chloride injury of the midportion of the common carotid arteries of apoE(-/-) mice (n=22) induced formation of a neointima that contained smooth muscle cells, foam cells, neutral lipid, tissue factor, and von Willebrand factor. ferric chloride 21-36 coagulation factor III Mus musculus 214-227 11758967-6 2000 The interleukin-8 (IL-8) receptor knockout mice formed the slight thrombus in coronary arteries treated with ferric chloride. ferric chloride 109-124 chemokine (C-X-C motif) ligand 15 Mus musculus 4-17 11394286-4 2001 Considering the best conditions of coagulation/flotation (ferric chloride dose of 65 mg.L-1 and pH around 5.5), the ozone dose application of 6 mg.L-1 led to a significant level in the removal efficiency of COD (80.4%), BOD (79.0%), total phosphate (93.4%), apparent color (91.9%) and turbidity (97.0%), demonstrating that the system seems to be efficient and capable of promoting a high degree of sewage post-treatment, reducing the coagulant dose until 30%, with a consequent reduction in the sludge generation. ferric chloride 58-73 immunoglobulin kappa variable 1-16 Homo sapiens 88-91 11394286-4 2001 Considering the best conditions of coagulation/flotation (ferric chloride dose of 65 mg.L-1 and pH around 5.5), the ozone dose application of 6 mg.L-1 led to a significant level in the removal efficiency of COD (80.4%), BOD (79.0%), total phosphate (93.4%), apparent color (91.9%) and turbidity (97.0%), demonstrating that the system seems to be efficient and capable of promoting a high degree of sewage post-treatment, reducing the coagulant dose until 30%, with a consequent reduction in the sludge generation. ferric chloride 58-73 immunoglobulin kappa variable 1-16 Homo sapiens 147-150 10936501-0 2000 Z-335, a new thromboxane A(2) receptor antagonist, prevents arterial thrombosis induced by ferric chloride in rats. ferric chloride 91-106 thromboxane A2 receptor Rattus norvegicus 13-38 10958523-10 2000 GABA transporters GAT-1 and GAT-3 in the hippocampus were upregulated by FeCl3 injection into the amygdala. ferric chloride 73-78 solute carrier family 6 member 12 Rattus norvegicus 18-23 10958523-10 2000 GABA transporters GAT-1 and GAT-3 in the hippocampus were upregulated by FeCl3 injection into the amygdala. ferric chloride 73-78 solute carrier family 6 member 11 Rattus norvegicus 28-33 11406113-2 2001 In the presence of either Fe(2+) or Fe(3+) (100-200 microM of FeSO(4) or FeCl(3), respectively), 80-90% inhibition of ATP hydrolysis by PMA was observed. ferric chloride 73-80 membrane H(+)-ATPase 1 Zea mays 136-139 11758967-6 2000 The interleukin-8 (IL-8) receptor knockout mice formed the slight thrombus in coronary arteries treated with ferric chloride. ferric chloride 109-124 chemokine (C-X-C motif) ligand 15 Mus musculus 19-23 9536222-7 1998 The oxidizing agents FeCl3 and H2O2 up-regulated ICAM-1 expression in HaCaT cells but there was no clear relationship between the ability of agents to induce ICAM-1 expression and their ability to alter the levels of reduced glutathione. ferric chloride 21-26 intercellular adhesion molecule 1 Homo sapiens 49-55 10022010-8 1999 Supplementation with 50 microM of ferric chloride to the medium completely reversed the inhibitory effects of the antibodies and lactoferrin. ferric chloride 34-49 lactotransferrin Bos taurus 129-140 9604714-4 1998 Oxidation of the MMP-2 using a FeCl3/ascorbate system resulted in impaired ability to degrade [3H]gelatin compared to control. ferric chloride 31-36 matrix metallopeptidase 2 Homo sapiens 17-22 10545417-2 1999 We have examined the effects of the iron(III) chelator deferroxamine (DFO) and iron (FeCl(3)) on UVB (290-320 nm)-induced activator protein 1 (AP-1) signaling. ferric chloride 85-92 JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens 122-141 10545417-2 1999 We have examined the effects of the iron(III) chelator deferroxamine (DFO) and iron (FeCl(3)) on UVB (290-320 nm)-induced activator protein 1 (AP-1) signaling. ferric chloride 85-92 JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens 143-147 10545417-5 1999 Treatment with FeCl(3) a minimum of 6 h prior to UVB potentiated the UVB induction of AP-1 transactivation by 2-3-fold. ferric chloride 15-22 JunB proto-oncogene, AP-1 transcription factor subunit Homo sapiens 86-90 9851740-9 1998 The addition of FeCl3 to DFA diminished the augmenting effect on the release of IL-1-beta, suggesting that the mechanism of action involved iron chelation. ferric chloride 16-21 interleukin 1 beta Homo sapiens 80-89 9705206-1 1998 Exposure of intact rabbit erythrocytes or erythrocyte lysates to ascorbic acid/FeCl3 in a glucose-free saline promoted a rapid decline in reduced glutathione and this response was paralleled by inactivation of hexokinase. ferric chloride 79-84 hexokinase-2 Oryctolagus cuniculus 210-220 9977433-0 1995 Magnetic properties of CocMn1-cCl2-FeCl3 graphite bi-intercalation compounds. ferric chloride 35-40 C-C motif chemokine ligand 2 Homo sapiens 30-34 9409707-5 1997 Perfusion of FeCl3 (200 microM) along with MPP+ (2.5 mM) and DES (100 microM) on day 1 completely abolished on day 2 the neuroprotective effect found with MPP+ (2.5 mM) and DES (100 microM). ferric chloride 13-18 M-phase phosphoprotein 6 Homo sapiens 155-158 8662001-1 1996 Our experiments show that when MgCl2 is replaced by FeCl3, PNPase becomes able to synthesize deoxyheteropolymers using deoxyribonucleoside-5"-diphosphates (dNDPs). ferric chloride 52-57 polyribonucleotide nucleotidyltransferase 1 Homo sapiens 59-65 8036011-3 1994 We have studied the capacity of hydrogen peroxide plus ferric chloride (FeCl3) to induce base pair changes in the hotspot codons 248 and 249 of the p53 tumor suppressor gene in human fibroblasts. ferric chloride 55-70 tumor protein p53 Homo sapiens 148-151 8036011-3 1994 We have studied the capacity of hydrogen peroxide plus ferric chloride (FeCl3) to induce base pair changes in the hotspot codons 248 and 249 of the p53 tumor suppressor gene in human fibroblasts. ferric chloride 72-77 tumor protein p53 Homo sapiens 148-151 8036011-7 1994 It is evident that H2O2/FeCl3 possesses essentially the same mutagenic specificity for codons 249 and 250 of p53 as bulky carcinogens such as aflatoxin B1, benzo(a)pyrene or heterocyclic amines. ferric chloride 24-29 tumor protein p53 Homo sapiens 109-112 7887224-11 1994 When 10 microM ferric chloride was included in the ACL prestimulation phase, there was a marked depression in ADA integration into stem cells as compared to heme or non-heme controls. ferric chloride 15-30 adenosine deaminase Homo sapiens 110-113 8106324-6 1994 Complementation of the pvdA mutation was under stringent iron control; both pyoverdin synthesis and L-Orn N5-oxygenase activity were undetectable in cells of the trans-complemented mutant which had been grown in the presence of 100 microM FeCl3. ferric chloride 239-244 L-ornithine N5-oxygenase Pseudomonas aeruginosa PAO1 23-27 33940654-6 2022 Furthermore, the addition of ferric chloride (FeCl3) to plasma propagated thrombin generation in a FVIII and FIX-dependent manner suggesting that iron positively affects blood coagulation. ferric chloride 29-44 coagulation factor II, thrombin Homo sapiens 74-82 1627803-7 1992 Ferric chloride stimulated Tf-independent gallium uptake. ferric chloride 0-15 transferrin Homo sapiens 27-29 1928358-5 1991 In the presence of 20 microM FeCl3, both TGF-beta 1 and 80% O2 produced marked cellular desquamation from culture dishes. ferric chloride 29-34 transforming growth factor beta 1 Bos taurus 41-51 2303008-0 1990 Lipid peroxidation and glutathione peroxidase, glutathione reductase, superoxide dismutase, catalase, and glucose-6-phosphate dehydrogenase activities in FeCl3-induced epileptogenic foci in the rat brain. ferric chloride 154-159 glutathione-disulfide reductase Rattus norvegicus 47-68 2303008-0 1990 Lipid peroxidation and glutathione peroxidase, glutathione reductase, superoxide dismutase, catalase, and glucose-6-phosphate dehydrogenase activities in FeCl3-induced epileptogenic foci in the rat brain. ferric chloride 154-159 catalase Rattus norvegicus 92-100 2303008-0 1990 Lipid peroxidation and glutathione peroxidase, glutathione reductase, superoxide dismutase, catalase, and glucose-6-phosphate dehydrogenase activities in FeCl3-induced epileptogenic foci in the rat brain. ferric chloride 154-159 glucose-6-phosphate dehydrogenase Rattus norvegicus 106-139 8012290-4 1994 ethylenediaminetetra-acetic acid (EDTA)-FeCl3 and diethylenetriaminepenta-acetic acid (DTPA)-FeCl3 was dramatically higher than the enhancement in the reduction of cytochrome c and DCIP. ferric chloride 93-98 LOC106992390 Macaca mulatta 164-176 8012290-6 1994 Superoxide dismutase (SOD) decreased EDTA-FeCl3 enhanced reduction of cytochrome c by 15%, but had no effect on the NADPH oxidation and DCIP reduction, whereas it significantly enhanced DTPA-FeCl3 stimulated NADPH oxidation, decreased cytochrome c reduction by 8% and did not affect DCIP reduction. ferric chloride 42-47 LOC106992390 Macaca mulatta 70-82 1322122-5 1992 Addition of FeCl3 to the medium appeared to decrease the inhibitory effect of zinc on hypoxia-induced EPO synthesis, implying that zinc may interfere with an iron-dependent step in EPO regulation. ferric chloride 12-17 erythropoietin Homo sapiens 102-105 1322122-5 1992 Addition of FeCl3 to the medium appeared to decrease the inhibitory effect of zinc on hypoxia-induced EPO synthesis, implying that zinc may interfere with an iron-dependent step in EPO regulation. ferric chloride 12-17 erythropoietin Homo sapiens 181-184 1788827-4 1991 These findings indicate that thrombin plays a principle role in the platelet-dependent process of arterial thrombosis in FeCl3-damaged rat carotid arteries. ferric chloride 121-126 coagulation factor II Rattus norvegicus 29-37 1715897-7 1991 PLC/PRF/5 cells were also inhibited when maintained in medium containing equimolar concentrations of DFX and FeCl3 and in medium containing equimolar concentrations of DFX and FeSO4. ferric chloride 109-114 heparan sulfate proteoglycan 2 Homo sapiens 0-3 1986776-6 1991 Similar changes in all of these parameters occurred after exposure of surfactant to FeCl3/ASC. ferric chloride 84-89 PYD and CARD domain containing Homo sapiens 90-93 2124140-6 1990 HPLC and TLC analysis of the tyrosine-tyrosinase reaction in the presence of excess TU showed that the substrate is progressively consumed and a major hitherto unknown product (lambda max = 284 nm), positive to ninhydrin and ferric chloride, is concomitantly formed. ferric chloride 225-240 tyrosinase Homo sapiens 38-48 33940654-6 2022 Furthermore, the addition of ferric chloride (FeCl3) to plasma propagated thrombin generation in a FVIII and FIX-dependent manner suggesting that iron positively affects blood coagulation. ferric chloride 29-44 coagulation factor VIII Homo sapiens 99-104 34710451-3 2022 A novel biochar (KMCBC) derived from agriculture waste of corn cob was first time co-modified by potassium hydroxide (KOH), ferric chloride (FeCl3) and zinc chloride (ZnCl2), which showed the greater adsorption amount (410 mg g-1 at 298 K) for imidacloprid (IMI). ferric chloride 124-139 metabolism of cobalamin associated B Homo sapiens 63-66 3470755-0 1987 Ferric chloride-catalyzed activation of hydrogen peroxide for the demethylation of N,N-dimethylaniline, the epoxidation of olefins, and the oxidative cleavage of vicinal diols in acetonitrile: a reaction mimic for cytochrome P-450. ferric chloride 0-15 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 214-230 34731962-1 2022 Hybrid flocculant polyacrylamide-ferric chloride (PAM-FeCl3) was developed to improve the dewaterability of sewage sludge and the dewatering performance, properties of treated sludge, composition and morphology distribution of extracellular polymeric substance (EPS) were investigated. ferric chloride 33-48 peptidylglycine alpha-amidating monooxygenase Homo sapiens 50-53 34967109-1 2022 BACKGROUND: Previously, we showed that histidine-rich glycoprotein (HRG) binds factor (F) XIIa with high affinity, inhibits FXII autoactivation and FXIIa-mediated activation of FXI, and attenuates ferric chloride-induced arterial thrombosis in mice. ferric chloride 197-212 histidine-rich glycoprotein Mus musculus 39-66 34967109-1 2022 BACKGROUND: Previously, we showed that histidine-rich glycoprotein (HRG) binds factor (F) XIIa with high affinity, inhibits FXII autoactivation and FXIIa-mediated activation of FXI, and attenuates ferric chloride-induced arterial thrombosis in mice. ferric chloride 197-212 histidine-rich glycoprotein Mus musculus 68-71 2590168-7 1989 Finally, the haem precursors ALA and FeCl3, when injected together into the fluid surrounding embryos, inhibited both the elevations in ALA synthase mass and RNA concentration brought about by porphyrogenic agents in liver, kidney and intestine. ferric chloride 37-42 5'-aminolevulinate synthase 1 Gallus gallus 136-148 2590168-8 1989 Thus the results indicated that: (1) certain porphyrogenic agents increased ALA synthase mass and RNA in chick-embryo intestine and kidney, in addition to liver; (2) ALA and FeCl3 inhibited the elevations; and (3) the sizes of ALA synthase"s subunit as well as the enzyme"s mRNA appeared identical, in each case, in all tissues examined. ferric chloride 174-179 5'-aminolevulinate synthase 1 Gallus gallus 76-88 2590168-8 1989 Thus the results indicated that: (1) certain porphyrogenic agents increased ALA synthase mass and RNA in chick-embryo intestine and kidney, in addition to liver; (2) ALA and FeCl3 inhibited the elevations; and (3) the sizes of ALA synthase"s subunit as well as the enzyme"s mRNA appeared identical, in each case, in all tissues examined. ferric chloride 174-179 5'-aminolevulinate synthase 1 Gallus gallus 227-239 2543489-4 1989 The expression of transferrin- and lactoferrin-binding activity was induced by addition of ethylenediamine di-o-phenylacetic acid and reversed by excess FeCl3, indicating regulation by the level of available iron in the medium. ferric chloride 153-158 transferrin Homo sapiens 18-29 2459594-1 1988 Isolated and purified microsomal NADH-cytochrome b5 reductase (EC 1.6.2.2) was incubated with bleomycin (BLM) and FeCl3 in the presence of NADH. ferric chloride 114-119 cytochrome b5 type A Homo sapiens 38-51 2822020-7 1987 Further, in the presence of insulin, the insulin-receptor kinase activity was also observed to be more sensitive to oxidation by H2O2 and FeCl3/ascorbate compared with insulin receptors in the absence of insulin. ferric chloride 138-144 insulin Homo sapiens 28-35 2822020-7 1987 Further, in the presence of insulin, the insulin-receptor kinase activity was also observed to be more sensitive to oxidation by H2O2 and FeCl3/ascorbate compared with insulin receptors in the absence of insulin. ferric chloride 138-144 insulin Homo sapiens 41-48 2822020-7 1987 Further, in the presence of insulin, the insulin-receptor kinase activity was also observed to be more sensitive to oxidation by H2O2 and FeCl3/ascorbate compared with insulin receptors in the absence of insulin. ferric chloride 138-144 insulin Homo sapiens 41-48 2822020-7 1987 Further, in the presence of insulin, the insulin-receptor kinase activity was also observed to be more sensitive to oxidation by H2O2 and FeCl3/ascorbate compared with insulin receptors in the absence of insulin. ferric chloride 138-144 insulin Homo sapiens 41-48 34214595-8 2021 In ferric chloride (FeCl3)-induced carotid thrombus models, MnO2/uPA@pep-Fuco specifically targeted to the obstructive artery (3.43 times that of the normal artery) and significantly decreased the percentage of thrombus closure (5.99 +- 5.07%), demonstrating the superior thrombolysis ability. ferric chloride 3-18 proline rich acidic protein 1 Homo sapiens 65-68 35267019-7 2022 Rev-erbalpha deletion also reduced ferric chloride-induced carotid arterial occlusive thrombosis, prevented collagen/epinephrine-induced pulmonary thromboembolism, and protected against microvascular microthrombi obstruction and infarct expansion in an acute myocardial infarction model. ferric chloride 35-50 nuclear receptor subfamily 1, group D, member 1 Mus musculus 0-12 2462531-1 1987 When NADPH-cytochrome P-450 reductase isolated from rat liver microsomes was aerobically incubated with bleomycin, FeCl3, NADPH and DNA parallel NADPH and oxygen were consumed and malondialdehyde was formed. ferric chloride 115-120 cytochrome p450 oxidoreductase Rattus norvegicus 5-37 3566276-4 1987 When delta-aminolevulinic acid (ALA) and FeCl3 were added into the culture medium (1 mM and 5 microM, respectively), the increase in ALA synthase mRNA brought on by AIA was also inhibited. ferric chloride 41-46 5'-aminolevulinate synthase 1 Gallus gallus 133-145 6477639-1 1984 GABA-transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSA-DH) activities were measured in the mitochondrial fractions from the cobalt- and FeCl3-induced chronic epileptogenic foci in the rat brain. ferric chloride 153-158 4-aminobutyrate aminotransferase Rattus norvegicus 0-17 3722204-1 1986 Incubation of human plasma fibronectin in the presence of low concentrations of FeCl3 or CuSO4 led to the formation of disulfide-bonded multimers as revealed by analysis in sodium dodecyl sulfate-polyacrylamide gel electrophoresis under nonreducing or reducing conditions. ferric chloride 80-85 fibronectin 1 Homo sapiens 27-38 3722204-5 1986 When incubated in the presence of FeCl3, the Mr 30,000 NH2-terminal, Mr 40,000 gelatin-binding, and the Mr 120,000-140,000 COOH-terminal fragments of fibronectin formed disulfide-bonded polymers, whereas only the Mr 140,000 fragment was polymerized in the presence of CuSO4. ferric chloride 34-39 fibronectin 1 Homo sapiens 150-161 3722204-6 1986 Disulfide-bonded polymers were also formed in the presence of FeCl3 but not CuSO4 when the free sulfhydryl groups of fibronectin were blocked by N-ethylmaleimide. ferric chloride 62-67 fibronectin 1 Homo sapiens 117-128 3722204-7 1986 The results suggest that in the presence of CuSO4, disulfide-bonded polymerization of fibronectin may involve predominantly the free sulfhydryl groups, whereas in the presence of FeCl3, also the intramolecular disulfides may exchange to form disulfides between separate fibronectin molecules. ferric chloride 179-184 fibronectin 1 Homo sapiens 86-97 6477639-1 1984 GABA-transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSA-DH) activities were measured in the mitochondrial fractions from the cobalt- and FeCl3-induced chronic epileptogenic foci in the rat brain. ferric chloride 153-158 4-aminobutyrate aminotransferase Rattus norvegicus 19-25 6477639-1 1984 GABA-transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSA-DH) activities were measured in the mitochondrial fractions from the cobalt- and FeCl3-induced chronic epileptogenic foci in the rat brain. ferric chloride 153-158 aldehyde dehydrogenase 5 family, member A1 Rattus norvegicus 68-74 6477639-6 1984 The measurements of the enzyme activities in the mirror (secondary) foci showed that, except for a brief stimulation of SSA-DH activity in the mirror focus in FeCl3 epileptic animals, the enzyme activities remained unchanged. ferric chloride 159-164 aldehyde dehydrogenase 5 family, member A1 Rattus norvegicus 120-126 6655517-3 1983 Within 5 minutes of giving of 5.6 micrograms Fe (FeCl3), in 0.50 ml 0.01 M HCl, 0.9% NaCl, the pH of the lumen had climbed above pH 4, where Fe3+ is insoluble; reached 6.8 by 10-15 minutes. ferric chloride 45-47 prolyl 4-hydroxylase, transmembrane Rattus norvegicus 129-133 6655517-3 1983 Within 5 minutes of giving of 5.6 micrograms Fe (FeCl3), in 0.50 ml 0.01 M HCl, 0.9% NaCl, the pH of the lumen had climbed above pH 4, where Fe3+ is insoluble; reached 6.8 by 10-15 minutes. ferric chloride 49-54 prolyl 4-hydroxylase, transmembrane Rattus norvegicus 129-133 7296013-2 1981 In intestinal mucosal tissue a transferrin-like immunoreactivity (TLIR) was determined after loading with 59Fe-(FeCl3) in vivo. ferric chloride 112-117 transferrin Rattus norvegicus 31-42 6628443-5 1983 Results of equilibrium dialysis, showed that binding of 67Ga to transferrin was inhibited by the administration of FeCl3. ferric chloride 115-120 transferrin Homo sapiens 64-75 7053127-1 1981 Enhancement of spin-lattice relaxation using oral ferric chloride and using inhaled oxygen is illustrated. ferric chloride 50-65 spindlin 1 Homo sapiens 15-19 7053127-2 1981 A 0.06% solution of ferric chloride reduced the spin-lattice relaxation time in the fundus of the stomach from 730 ms to 285 ms. Ferric chloride may be useful as a bowel-labeling agent. ferric chloride 20-35 spindlin 1 Homo sapiens 48-52 7053127-2 1981 A 0.06% solution of ferric chloride reduced the spin-lattice relaxation time in the fundus of the stomach from 730 ms to 285 ms. Ferric chloride may be useful as a bowel-labeling agent. ferric chloride 129-144 spindlin 1 Homo sapiens 48-52 17743969-2 1965 At 5 x 10(-7)M ferric chloride or 10(-8)M cupric chloride, breakdown of hiydrogen peroxide was significant at -11 degrees and -18 degrees but negligible at +1 degrees C. Ascorbic acid oxidation was faster in ice both with or without added metalion. ferric chloride 15-30 carboxylesterase 2 Homo sapiens 208-211 6106903-1 1980 Sensitivity of glutamine synthetase assay by the hydroxamate method can be doubled by replacing ferric chloride with ferric nitrate of ferric perchlorate, each with the appropriate acid. ferric chloride 96-111 glutamate-ammonia ligase Homo sapiens 15-35 1174530-8 1975 Fe(NH4)2(SO4)2 and especially FeCl3 were found to yield nonspecifically bound iron when added to transferrin or serum. ferric chloride 30-35 serotransferrin Oryctolagus cuniculus 97-108 4345350-12 1972 The addition of FeCl(3) to anaerobic particles caused an oxidation of cytochrome b when this region of the respiratory chain was isolated by treatment with rotenone and antimycin A. ferric chloride 16-23 mitochondrially encoded cytochrome b Homo sapiens 70-82 239854-1 1975 Endotoxin (lipopolysaccharide, LPS) treated with ferric chloride was tested for its potential as a non-toxic agent for enhancement of non-specific host resistance. ferric chloride 49-64 toll-like receptor 4 Mus musculus 31-34 33512448-7 2021 Importantly, FVIII-QQ demonstrated approximately 5-fold increased procoagulant function relative to FVIII-WT in the tail clip and ferric chloride injury models in hemophilia A (HA) mice. ferric chloride 130-145 coagulation factor VIII Mus musculus 13-18 13437463-0 1957 Interference of bromide in the Zak ferric chloride-sulfuric acid cholesterol method, and means of eliminating this interference. ferric chloride 35-50 mitogen-activated protein kinase kinase kinase 20 Homo sapiens 31-34 33830628-5 2021 RESULTS: The time to ferric chloride-induced occlusion of the carotid artery in CD248 KO mice was significantly longer than in WT mice. ferric chloride 21-36 CD248 antigen, endosialin Mus musculus 80-85 33866501-7 2021 Phosphate can inhibit the formation of FeOH2+ and Fe(OH)2+ in the ferric chloride hydrolysis but promote the formation of FeOOH and Fe(OH)2+ in the ferrate decomposition. ferric chloride 66-81 general transcription factor IIE subunit 1 Homo sapiens 50-57