PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
16460014-4	2006	UV/vis absorbance spectra of P450(eryF) demonstrated that binding occurs with apparent negative homotropic cooperativity for TST and positive homotropic cooperativity for 9-AP with Hill-equation-derived dissociation constants of K(S) = 4 and 200 microM, respectively.	9-aminophenanthrene	171-175	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	29-39
16460014-3	2006	Here, we use UV/vis and heteronuclear nuclear magnetic resonance (NMR) spectroscopic techniques to study the mechanism and thermodynamics of the binding of two 9-aminophenanthrene (9-AP) and testosterone (TST) molecules to the erythromycin-metabolizing bacterial P450(eryF).	9-aminophenanthrene	160-179	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	263-273
16460014-3	2006	Here, we use UV/vis and heteronuclear nuclear magnetic resonance (NMR) spectroscopic techniques to study the mechanism and thermodynamics of the binding of two 9-aminophenanthrene (9-AP) and testosterone (TST) molecules to the erythromycin-metabolizing bacterial P450(eryF).	9-aminophenanthrene	181-185	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	263-273
15237852-7	2004	Furthermore, the results provide proof of principle for NMR as a method for studying CYP allosterism, and demonstrate that the model ligand 9-aminophenanthrene binds in two discrete events to individual subsites within the active site of CYP(eryF).	9-aminophenanthrene	140-159	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	85-88
15237852-7	2004	Furthermore, the results provide proof of principle for NMR as a method for studying CYP allosterism, and demonstrate that the model ligand 9-aminophenanthrene binds in two discrete events to individual subsites within the active site of CYP(eryF).	9-aminophenanthrene	140-159	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	238-241
12642459-6	2003	A comparative study with CYP3A4 revealed a similar increase in the binding affinity of 9-AP for the enzyme at low ANF concentrations but some competition at higher ANF concentrations.	9-aminophenanthrene	87-91	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	25-31