PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
18164204-4	2008	Further modification resulted in the discovery of 2-hydroxymethylimidazo[1,2-a]pyridine 2e (FXa IC(50)=0.0090 microM), which was found to be a selective and orally bioavailable FXa inhibitor with reduced CYP3A4 inhibition.	2-hydroxymethylimidazo[1,2-a]pyridine 2e	50-90	coagulation factor X	Homo sapiens	92-95
18164204-4	2008	Further modification resulted in the discovery of 2-hydroxymethylimidazo[1,2-a]pyridine 2e (FXa IC(50)=0.0090 microM), which was found to be a selective and orally bioavailable FXa inhibitor with reduced CYP3A4 inhibition.	2-hydroxymethylimidazo[1,2-a]pyridine 2e	50-90	coagulation factor X	Homo sapiens	177-180
18164204-4	2008	Further modification resulted in the discovery of 2-hydroxymethylimidazo[1,2-a]pyridine 2e (FXa IC(50)=0.0090 microM), which was found to be a selective and orally bioavailable FXa inhibitor with reduced CYP3A4 inhibition.	2-hydroxymethylimidazo[1,2-a]pyridine 2e	50-90	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	204-210