PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 18790752-4 2008 N-&-N1 shows exquisite selectivity for CDKs, with 2- to 3-fold enhanced potency compared with (R)-roscovitine. n-& 0-6 cyclin dependent kinase 2 Homo sapiens 43-47 18790752-5 2008 Inhibition of retinoblastoma protein phosphorylation and RNA polymerase II Ser2 phosphorylation in neuroblastoma SH-SY5Y cells exposed to N-&-N1 indicates that N-&-N1 is able to inhibit CDKs in a cellular context. n-& 138-144 cyclin dependent kinase 2 Homo sapiens 194-198 18790752-5 2008 Inhibition of retinoblastoma protein phosphorylation and RNA polymerase II Ser2 phosphorylation in neuroblastoma SH-SY5Y cells exposed to N-&-N1 indicates that N-&-N1 is able to inhibit CDKs in a cellular context. n-& 138-144 jagged canonical Notch ligand 2 Homo sapiens 75-79 18790752-5 2008 Inhibition of retinoblastoma protein phosphorylation and RNA polymerase II Ser2 phosphorylation in neuroblastoma SH-SY5Y cells exposed to N-&-N1 indicates that N-&-N1 is able to inhibit CDKs in a cellular context. n-& 164-170 jagged canonical Notch ligand 2 Homo sapiens 75-79 18790752-5 2008 Inhibition of retinoblastoma protein phosphorylation and RNA polymerase II Ser2 phosphorylation in neuroblastoma SH-SY5Y cells exposed to N-&-N1 indicates that N-&-N1 is able to inhibit CDKs in a cellular context. n-& 164-170 cyclin dependent kinase 2 Homo sapiens 194-198 18790752-8 2008 A competitive assay shows that, compared with (R)-roscovitine, N-&-N1 has reduced affinity for Erk2 and pyridoxal kinase. n-& 63-69 mitogen-activated protein kinase 1 Homo sapiens 99-103