PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 18646720-13 2008 The numbers of Foxp3+ CD4 CD25+ regulatory T cells were higher in the fodrin groups than in the PBS and GST control groups (all P < 0.05). pbs 96-99 forkhead box P3 Mus musculus 15-20 18004403-8 2008 Following I-R, AAV/TGFbeta(1)(ACT)-overexpressing rats had much smaller infarct size (P<0.01 vs PBS group), which was also related to reduced activation of NADPH oxidase and NF-kappaB, and lower levels of malondialdehyde in I-R tissues. pbs 99-102 transforming growth factor, beta 1 Mus musculus 19-29 18709950-9 2008 On the 7th and 14th days after the burning, the expression of integrin beta1 in the cornea epithelial cells of TGF-beta1 group was remarkably higher than that of the PBS group (P < 0.05). pbs 166-169 LOC100009173 Oryctolagus cuniculus 62-76 17971079-7 2008 When we used late AD markers such as the conformational Tau-66 epitope and MN423 (cleavage at site E(391)) in Pick bodies (PBs), the overlap was significantly less. pbs 123-126 protein interacting with PRKCA 1 Homo sapiens 110-114 18158957-6 2008 The proliferation and number of donor T cells were significantly lower at day 30 post-BMT in the PBS-treated B6.IL-7(-/-) recipients compared with the IL-7-treated B6.IL-7(-/-) mice. pbs 97-100 interleukin 7 Homo sapiens 112-116 17971079-8 2008 Furthermore, following morphological quantification, we found significantly higher numbers of phosphorylated tau in PBs. pbs 116-119 microtubule associated protein tau Homo sapiens 109-112 17665443-9 2007 The expression and activity of matrix metalloproteinases 2 and 9, which participate in angiogenesis, was impaired in response to IL-13 as compared with AxCANI and PBS treatment. pbs 163-166 matrix metallopeptidase 2 Rattus norvegicus 31-64 19111193-4 2008 PBs also contain mRNA and eIF4E but lack other preinitiation factors and contain instead a number of proteins associated with mRNA decay such as DCP1a, DCP2, hedls/GE-1, p54/RCK. pbs 0-3 eukaryotic translation initiation factor 4E Homo sapiens 26-31 19111193-4 2008 PBs also contain mRNA and eIF4E but lack other preinitiation factors and contain instead a number of proteins associated with mRNA decay such as DCP1a, DCP2, hedls/GE-1, p54/RCK. pbs 0-3 decapping mRNA 1A Homo sapiens 145-150 19111193-4 2008 PBs also contain mRNA and eIF4E but lack other preinitiation factors and contain instead a number of proteins associated with mRNA decay such as DCP1a, DCP2, hedls/GE-1, p54/RCK. pbs 0-3 decapping mRNA 2 Homo sapiens 152-156 19111193-4 2008 PBs also contain mRNA and eIF4E but lack other preinitiation factors and contain instead a number of proteins associated with mRNA decay such as DCP1a, DCP2, hedls/GE-1, p54/RCK. pbs 0-3 enhancer of mRNA decapping 4 Homo sapiens 158-163 19111193-4 2008 PBs also contain mRNA and eIF4E but lack other preinitiation factors and contain instead a number of proteins associated with mRNA decay such as DCP1a, DCP2, hedls/GE-1, p54/RCK. pbs 0-3 enhancer of mRNA decapping 4 Homo sapiens 164-168 19111193-4 2008 PBs also contain mRNA and eIF4E but lack other preinitiation factors and contain instead a number of proteins associated with mRNA decay such as DCP1a, DCP2, hedls/GE-1, p54/RCK. pbs 0-3 interferon induced protein with tetratricopeptide repeats 2 Homo sapiens 170-173 19111193-4 2008 PBs also contain mRNA and eIF4E but lack other preinitiation factors and contain instead a number of proteins associated with mRNA decay such as DCP1a, DCP2, hedls/GE-1, p54/RCK. pbs 0-3 mitogen-activated protein kinase kinase kinase 19 Homo sapiens 174-177 19111193-5 2008 Many other proteins (e.g., argonaute, FAST, RAP-55, TTP) and microRNAs are present in both SGs and PBs, sometimes shepherding specific mRNA transcripts between the translation and decay machineries. pbs 99-102 LSM14A mRNA processing body assembly factor Homo sapiens 44-50 19111193-5 2008 Many other proteins (e.g., argonaute, FAST, RAP-55, TTP) and microRNAs are present in both SGs and PBs, sometimes shepherding specific mRNA transcripts between the translation and decay machineries. pbs 99-102 SH3 domain binding protein 4 Homo sapiens 52-55 18476520-14 2007 Rev-caspase-3 treatment significantly prolonged survival, the mean survival duration was (213 +/- 16) days, and suppressed tumor growth (tumor growth suppression rate was 70%), when compared with treatment with phosphate buffered saline (PBS). pbs 238-241 REV3 like, DNA directed polymerase zeta catalytic subunit Mus musculus 0-3 18371631-4 2007 Cyt c shows a couple of quasi-reversible and well-defined cyclic voltammetry peaks with a formal potential (E(0")) of -0.16 V (versus Ag/AgCl) in pH 7.0 phosphate buffer solution (PBS). pbs 180-183 cytochrome c, somatic Homo sapiens 0-5 18087238-12 2007 Transcripts for the CCR7 ligands, CCL19 and CCL21b, were found after LPS or PBS injection but not in naive iris-ciliary bodies. pbs 76-79 chemokine (C-C motif) receptor 7 Mus musculus 20-24 18087238-12 2007 Transcripts for the CCR7 ligands, CCL19 and CCL21b, were found after LPS or PBS injection but not in naive iris-ciliary bodies. pbs 76-79 chemokine (C-C motif) ligand 19 Mus musculus 34-39 18087238-12 2007 Transcripts for the CCR7 ligands, CCL19 and CCL21b, were found after LPS or PBS injection but not in naive iris-ciliary bodies. pbs 76-79 chemokine (C-C motif) ligand 21B (leucine) Mus musculus 44-50 18361482-4 2008 IGF-1-incorporated mineralized scaffolds demonstrated slow controlled release over a 30 day period when they were incubated in phosphate-buffered saline (PBS) at 37 degrees C. Bone marrow stromal cell (BMSC) function on three different types of scaffolds, such as control (non-mineralized) scaffolds, mineralized scaffolds, and IGF-1-incorporated mineralized scaffolds was also investigated. pbs 154-157 insulin like growth factor 1 Homo sapiens 0-5 18261307-8 2007 Another 40 mice underwent intraperitoneal injection of AO cells to establish intraperitoneal transplanted tumor models, 21 days later the rats were divided into 4 equal groups to be injected intraperitoneally with AdHT-rev-casp3, Ad-rev-casp3, Ad-EGFG, or PBS, the survival rate was observed, and the blood levels of alanine transaminase (ALT) and aspartate transaminase (AST) were detected. pbs 256-259 REV3 like, DNA directed polymerase zeta catalytic subunit Mus musculus 219-222 17923087-4 2007 We have partially purified a large PBS-mediated silencing complex and identified TRIM28 (Kap-1), a known transcriptional silencer, as an integral component of the complex. pbs 35-38 tripartite motif containing 28 Homo sapiens 81-87 17923087-4 2007 We have partially purified a large PBS-mediated silencing complex and identified TRIM28 (Kap-1), a known transcriptional silencer, as an integral component of the complex. pbs 35-38 tripartite motif containing 28 Homo sapiens 89-94 17923087-5 2007 We show that RNAi-mediated knockdown of TRIM28 in EC and ES cells relieves the restriction and that TRIM28 is bound to the PBS in vivo when restriction takes place. pbs 123-126 tripartite motif containing 28 Homo sapiens 100-106 17883721-12 2007 The transfer of CD4+ T cells from mesenteric lymph nodes of OVA-sensitized and OVA-challenged mice triggered airway hyperreactivity and eosinophilic airway inflammation in recipients aerosol challenged with OVA, but not with PBS. pbs 225-228 CD4 antigen Mus musculus 16-19 17883721-12 2007 The transfer of CD4+ T cells from mesenteric lymph nodes of OVA-sensitized and OVA-challenged mice triggered airway hyperreactivity and eosinophilic airway inflammation in recipients aerosol challenged with OVA, but not with PBS. pbs 225-228 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 60-63 17883721-12 2007 The transfer of CD4+ T cells from mesenteric lymph nodes of OVA-sensitized and OVA-challenged mice triggered airway hyperreactivity and eosinophilic airway inflammation in recipients aerosol challenged with OVA, but not with PBS. pbs 225-228 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 79-82 17883721-12 2007 The transfer of CD4+ T cells from mesenteric lymph nodes of OVA-sensitized and OVA-challenged mice triggered airway hyperreactivity and eosinophilic airway inflammation in recipients aerosol challenged with OVA, but not with PBS. pbs 225-228 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 79-82 17727773-10 2007 (3) Quantitation by densitometry showed that the relative density of iNOS mRNA bands normalized to beta-actin was significantly higher in the OVA control than the PBS control (1.0 +/- 0.07 vs 0.48 +/- 0.07, P < 0.01). pbs 163-166 nitric oxide synthase 2 Rattus norvegicus 69-73 17603843-6 2007 Intranasal immunization of mice with rRF-255 overall induced higher concentrations of anti-RSV F-specific antibodies in both serum and saliva as compared with mice immunized intranasally with RSV or phosphate-buffered saline (PBS). pbs 226-229 mitochondrial ribosome recycling factor Rattus norvegicus 37-40 17804539-3 2007 We administered daily injections of murine IL-2 (0.4 mug in phosphate-buffered saline [PBS]) to pregnant mice during mid-gestation, and analyzed their offspring (IL-2 pups) in comparison to offspring of pregnant mice injected with vehicle only (PBS pups). pbs 87-90 interleukin 2 Mus musculus 43-47 17767052-11 2007 The levels of I-Abeta(g7), IFN-gamma, IL-1beta and Fas mRNA transcription in islets and IFN-gamma mRNA transcription in Peyer"s patch were both lower in the insulin group, and IL-4, TGF-beta mRNA levels were higher than those in the PBS group (P<0.05). pbs 233-236 insulin Homo sapiens 157-164 17368706-3 2007 We constructed an HIV-1 provirus in which the primer-binding site (PBS) was altered to be complementary to the 3" terminal 18-nucleotides of E. coli tRNA(Lys,3), which shares many bases with mammalian tRNA(Lys,3), and demonstrated that infectious virus was obtained only if the provirus was co-transfected with the plasmid encoding E. coli tRNA(Lys,3). pbs 67-70 mitochondrially encoded tRNA glycine Homo sapiens 201-211 17368706-3 2007 We constructed an HIV-1 provirus in which the primer-binding site (PBS) was altered to be complementary to the 3" terminal 18-nucleotides of E. coli tRNA(Lys,3), which shares many bases with mammalian tRNA(Lys,3), and demonstrated that infectious virus was obtained only if the provirus was co-transfected with the plasmid encoding E. coli tRNA(Lys,3). pbs 67-70 mitochondrially encoded tRNA glycine Homo sapiens 201-211 17262792-11 2007 Immunohistochemical analysis showed PBs" positive reaction on vimentin, CD45R0, and LCA markers, while in their vicinity, as well as inside them, numerous T-cells were observed. pbs 36-39 vimentin Homo sapiens 62-70 16872916-3 2007 In 0.10 M, pH 7.0 phosphate buffer solution (PBS), Cyt c showed a quasi-reversible electrochemical redox behavior with E(pc)=0.180 V, E(pa)=0.208 V (versus Ag/AgCl). pbs 45-48 cytochrome c, somatic Homo sapiens 51-56 17324393-9 2007 ASB activity was markedly reduced when phosphate-buffered saline (PBS) was used as buffer, consistent with inhibition of sulfatase activity by phosphate. pbs 66-69 arylsulfatase B Homo sapiens 0-3 17336273-13 2007 After transplantation of NTN-expressing cells, DA content in the lesioned striatum was significantly higher in the transgenic group than that in the void vector group or the PBS group (P<0.05). pbs 174-177 neurturin Rattus norvegicus 25-28 17368869-2 2007 Here, we report on the transport enhancing properties of mixtures of an anionic surfactant, sodium lauroylsarcosinate (NLS) and a non-ionic surfactant, sorbitan monolaurate (S20) in 1:1 phosphate buffered saline (PBS):ethanol (EtOH) solvent. pbs 213-216 ribosomal protein S20 Homo sapiens 174-177 17461494-12 2007 In the tumor metastasis model, the number and weight of disseminated tumors of mice treated with rvAdCMV/NK4 were much lower than those of the control groups (tumor number: 6.2 +/- 3.3 in rvAdCMV/NK4 group vs 22.9 +/- 7.6 in PBS group or 19.8 +/- 8.5 in Ad-LacZ group, P < 0.05; tumor weight: 324 +/- 176 mg in rvAdCMV/NK4 group vs 962 +/- 382 mg in PBS group or 1116 +/- 484 mg in Ad-LacZ group, P < 0.05). pbs 225-228 interleukin 32 Homo sapiens 105-108 17461494-12 2007 In the tumor metastasis model, the number and weight of disseminated tumors of mice treated with rvAdCMV/NK4 were much lower than those of the control groups (tumor number: 6.2 +/- 3.3 in rvAdCMV/NK4 group vs 22.9 +/- 7.6 in PBS group or 19.8 +/- 8.5 in Ad-LacZ group, P < 0.05; tumor weight: 324 +/- 176 mg in rvAdCMV/NK4 group vs 962 +/- 382 mg in PBS group or 1116 +/- 484 mg in Ad-LacZ group, P < 0.05). pbs 353-356 interleukin 32 Homo sapiens 105-108 17369404-2 2007 Here we present evidence that in human cells the proteins Tristetraprolin (TTP) and BRF-1 deliver ARE-mRNAs to processing bodies (PBs), cytoplasmic assemblies of mRNAs, and associated factors that promote translational silencing and mRNA decay. pbs 130-133 ZFP36 ring finger protein Homo sapiens 58-73 17369404-2 2007 Here we present evidence that in human cells the proteins Tristetraprolin (TTP) and BRF-1 deliver ARE-mRNAs to processing bodies (PBs), cytoplasmic assemblies of mRNAs, and associated factors that promote translational silencing and mRNA decay. pbs 130-133 ZFP36 ring finger protein Homo sapiens 75-78 17369404-2 2007 Here we present evidence that in human cells the proteins Tristetraprolin (TTP) and BRF-1 deliver ARE-mRNAs to processing bodies (PBs), cytoplasmic assemblies of mRNAs, and associated factors that promote translational silencing and mRNA decay. pbs 130-133 BRF1 RNA polymerase III transcription initiation factor subunit Homo sapiens 84-89 17369404-3 2007 First, depletion of endogenous TTP and BRF proteins, or overexpression of dominant-negative mutant TTP proteins, impairs the localization of reporter ARE-mRNAs in PBs. pbs 163-166 ZFP36 ring finger protein Homo sapiens 99-102 17369404-4 2007 Second, TTP and BRF-1 localize tethered mRNAs to PBs. pbs 49-52 ZFP36 ring finger protein Homo sapiens 8-11 17369404-4 2007 Second, TTP and BRF-1 localize tethered mRNAs to PBs. pbs 49-52 BRF1 RNA polymerase III transcription initiation factor subunit Homo sapiens 16-21 17369404-6 2007 ARE-mRNA localization in PBs is mediated by the TTP N- and C-terminal domains and occurs downstream from mRNA polysome release, which in itself is not sufficient for mRNA PB localization. pbs 25-28 ZFP36 ring finger protein Homo sapiens 48-51 17369404-7 2007 The accumulation of ARE-mRNAs in PBs is strongly enhanced when the mRNA decay machinery is rendered limiting by mRNA decay enzyme depletion or TTP/BRF-1 overexpression. pbs 33-36 ZFP36 ring finger protein Homo sapiens 143-146 17369404-7 2007 The accumulation of ARE-mRNAs in PBs is strongly enhanced when the mRNA decay machinery is rendered limiting by mRNA decay enzyme depletion or TTP/BRF-1 overexpression. pbs 33-36 BRF1 RNA polymerase III transcription initiation factor subunit Homo sapiens 147-152 17923231-6 2007 PBs are associated with mRNA decay and contain the decapping enzymes DCP1/2, the 5" to 3" exonuclease Xrn1, the Lsm proteins (1-7), and the scaffolding proteins hedls/GE-1 and GW182. pbs 0-3 decapping mRNA 1B Homo sapiens 69-75 16850182-4 2007 Starving of control fibroblasts resulted in lysosomal alkalinisation, relocation of cathepsin D to the cytosol, caspase-3 activation and, finally, cell death, which became evident 72 h after the start of exposure to PBS. pbs 216-219 cathepsin D Homo sapiens 84-95 16850182-4 2007 Starving of control fibroblasts resulted in lysosomal alkalinisation, relocation of cathepsin D to the cytosol, caspase-3 activation and, finally, cell death, which became evident 72 h after the start of exposure to PBS. pbs 216-219 caspase 3 Homo sapiens 112-121 17963321-2 2007 Infusion of TNF-alpha into the third cerebral ventricle in doses of 1 to 4 mug/rat suppressed 24-hour cumulative food and water intake dose-dependently, compared to an infusion of phosphate-buffered saline (PBS) (p < 0.05 for each). pbs 207-210 tumor necrosis factor Rattus norvegicus 12-21 17963321-3 2007 The infusion of 2 microg/rat TNF-alpha into the third cerebral ventricle elevated rectal temperature compared to PBS controls (p < 0.05). pbs 113-116 tumor necrosis factor Rattus norvegicus 29-38 16908068-5 2007 The results suggested that, the CD4(+)/CD8(+) ratio decreased over time in piglets inoculated with phosphate buffer saline (PBS) alone, however, it was stable in CpG ODN-inoculated piglets; the use of CpG ODN can prevent effectively the reduction of the proportion of CD4(+) T lymphocytes. pbs 124-127 CD4 antigen Mus musculus 32-35 17923231-6 2007 PBs are associated with mRNA decay and contain the decapping enzymes DCP1/2, the 5" to 3" exonuclease Xrn1, the Lsm proteins (1-7), and the scaffolding proteins hedls/GE-1 and GW182. pbs 0-3 5'-3' exoribonuclease 1 Homo sapiens 102-106 17923231-6 2007 PBs are associated with mRNA decay and contain the decapping enzymes DCP1/2, the 5" to 3" exonuclease Xrn1, the Lsm proteins (1-7), and the scaffolding proteins hedls/GE-1 and GW182. pbs 0-3 enhancer of mRNA decapping 4 Homo sapiens 167-181 17041149-2 2006 We previously showed that a fusion between the Phaseolus vulgaris vacuolar storage protein phaseolin and the N-terminal half of the Zea mays prolamin gamma-zein forms ER-located PBs. pbs 178-181 prolamin 50 kDa gamma zein Zea mays 150-160 17047197-15 2006 Intratumoral injection of Ad-deltaE1B-RLX inhibited the formation of lung metastases in mice (PBS = 268 mg of metastatic tumor per mouse and Ad-deltaE1B-RLX = 10 mg; difference = 258 mg, 95% CI = 94 to 426; P = .003, Mann-Whitney test). pbs 94-97 relaxin 1 Mus musculus 38-41 17047197-16 2006 Systemic treatment with Ad-deltaE1B-RLX completely inhibited the growth of Hep1 hepatocellular carcinomas (PBS = 20.2 mg of tumor per mouse and Ad-deltaE1B-RLX = 0 mg; difference = 20.2 mg, 95% CI = 3.7 to 36.7; P = .004, Mann-Whitney test). pbs 107-110 relaxin 1 Mus musculus 36-39 17201168-7 2006 As compared to tumors of control mice with intratumoral phosphate-buffered saline (PBS) injections, tumors of the ME-A and ME-M treated groups showed a decreased cell proliferation rate, as well as an increased cell necrosis and apoptosis rate. pbs 83-86 meander tail Mus musculus 114-118 16919835-4 2006 The results suggested that, the CD4(+)/CD8(+) ratio decreased significantly in weaned piglets inoculated with phosphate buffer saline (PBS) alone, however, it was stable in CpG ODN-inoculated piglets. pbs 135-138 CD4 antigen Mus musculus 32-35 16691201-6 2006 In contrast, the lesional skin of MCP-1-/- mice exhibited a dermal architecture similar to phosphate-buffered saline (PBS)-injected control and normal skin, with few inflammatory cells. pbs 118-121 chemokine (C-C motif) ligand 2 Mus musculus 34-39 16777417-4 2006 Evaluation in cytotoxicity assays, Boc-lysinated-betulonic acid dissolved in phosphate-buffered saline (PBS) containing 22% ethanol and 4% human serum albumin, has shown 95.7% inhibition of LNCaP prostate cancer cells in culture after 72 h incubation at a concentration of 100 microM, but with little effect on normally proliferating fibroblast cells. pbs 104-107 BOC cell adhesion associated, oncogene regulated Homo sapiens 35-38 16844973-5 2006 PBE-T provides facility to transform any PDB file into sequences of PBs. pbs 68-71 enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase Homo sapiens 0-3 16844973-7 2006 PBE-ALIGNm is a facility for mining SCOP database for similar structures based on the alignment of PBs. pbs 99-102 enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase Homo sapiens 0-3 16483370-12 2006 Neuropeptide Y (NPY) levels of corresponding brain extracts were measured by ELISA (OD) using anti-NPY antibody and showed an 18% decrease upon insulin injection (0.093 +/- 0.019) and a 50% increase upon glucagon injection (0.226 +/- 0.084) as compared to controls injected with PBS (0.114 +/- 0.040). pbs 279-282 neuropeptide Y Mus musculus 0-14 16730499-5 2006 RESULTS: The effect of an alpha-casein on fetal resorption rate was assessed following the unilateral injection of 150 microL of alpha-casein (1 mg/mL in PBS) and compared with the effect obtained following the contralateral injection of 150 microL PBS. pbs 154-157 casein alpha s1 Rattus norvegicus 26-38 16730499-6 2006 The unilateral injection of alpha-casein on day L(5) caused a significant increase in fetal resorption rate as compared with the contralateral uterine horn injected with PBS (p<.00001). pbs 170-173 casein alpha s1 Rattus norvegicus 28-40 16741053-6 2006 After incubation with 10 microM ET-1 for 5 mins, we observed a reduction of HTM cell area with respect to PBS-treated cells: 2425 +/- 876 microm2 versus 3125 +/- 987 microm2 (P < 0.001); and cells exhibited a retraction in shape and a reduction in number of indented profiles. pbs 106-109 endothelin 1 Homo sapiens 32-36 16765251-9 2006 RESULTS: Conductance showed a significant stimulatory effect of GM-CSF on arteriogenesis (collateral conductance [mL/min/mm Hg]: PBS, 37.7 +/- 5.4; GM-CSF continuous, 69.2 +/- 12.5; GM-CSF intermittent, 71.5 +/- 11.1). pbs 129-132 colony stimulating factor 2 Homo sapiens 64-70 16289506-2 2006 The results suggested that, the CD4+/CD8+ ratio decreased with age in piglets inoculated with vaccine alone or GpC ODN with vaccine or phosphate buffer saline (PBS), however, it was stable in piglets co-inoculated with CpG ODN and PRRS vaccine (p>0.05), the use of CpG ODN can prevent effectively the reduction of the proportion of CD4+ T lymphocytes. pbs 160-163 glycophorin C (Gerbich blood group) Homo sapiens 111-114 16483370-12 2006 Neuropeptide Y (NPY) levels of corresponding brain extracts were measured by ELISA (OD) using anti-NPY antibody and showed an 18% decrease upon insulin injection (0.093 +/- 0.019) and a 50% increase upon glucagon injection (0.226 +/- 0.084) as compared to controls injected with PBS (0.114 +/- 0.040). pbs 279-282 neuropeptide Y Mus musculus 16-19 16226779-4 2006 The results showed that MP2 was able to effectively restrict packaging of spliced viral RNA into viruses containing either NC mutations R10A and K11A or mutated 5" UTR sequence, such as DeltaGU3 that lacked the 112-GUCUGUUGUGUG-123 sequence of U5, D1 that was deleted of a 27 nt fragment immediately downstream of the primer binding site (PBS), Delta(306-325) that had the SL3 RNA element removed and MD2 that was missing the 328-GGAG-331 sequence. pbs 339-342 tryptase pseudogene 1 Homo sapiens 24-27 16472260-4 2006 METHODS: Review of published studies and analysis of the PBS criteria for the prescription of TNF inhibitors for the treatment of AS to assess whether the published criteria are evidence based. pbs 57-60 tumor necrosis factor Homo sapiens 94-97 16472260-7 2006 CONCLUSION: The current PBS criteria that need to be fulfilled for patients to receive subsidised treatment with TNF inhibitors for AS are not evidence based and will lead to the selection of patients with established disease while excluding patients with early disease. pbs 24-27 tumor necrosis factor Homo sapiens 113-116 16051303-4 2005 Initially, we investigated the ability of the molecular adjuvant C3d to enhance antibody responses to variant gp120 glycoproteins in phosphate-buffered saline (PBS). pbs 160-163 endogenous retrovirus group K member 13 Homo sapiens 65-68 16364915-7 2005 These observations suggest that multiple proteins involved in human decapping are important subunits of PBs and are activated on ARE-mRNAs by the protein TTP. pbs 104-107 SH3 domain binding protein 4 Homo sapiens 154-157 16247677-1 2005 cDNA encoding mature human placental variant growth hormone (HGH-V) was synthesized by retro-transcription polymerase chain reaction (RT-PCR) from total RNA recovered from human term-placenta and cloned in pBluescript plasmid (pBS) in Escherichia coli. pbs 227-230 growth hormone 1 Homo sapiens 45-59 16247677-1 2005 cDNA encoding mature human placental variant growth hormone (HGH-V) was synthesized by retro-transcription polymerase chain reaction (RT-PCR) from total RNA recovered from human term-placenta and cloned in pBluescript plasmid (pBS) in Escherichia coli. pbs 227-230 growth hormone 2 Homo sapiens 61-66 16246897-5 2005 In PBS-treated mice, GPx4 activities in lung, liver, kidney, and testes of GPx4+/- mice were 24-39% lower (P < 0.05) than in WT mice. pbs 3-6 glutathione peroxidase 4 Mus musculus 21-25 16246897-5 2005 In PBS-treated mice, GPx4 activities in lung, liver, kidney, and testes of GPx4+/- mice were 24-39% lower (P < 0.05) than in WT mice. pbs 3-6 glutathione peroxidase 4 Mus musculus 75-79 16051303-6 2005 In PBS, the gp120DeltaC1/C5(C3d)(2) proteins are able to elicit gp120 binding antibodies more efficiently than gp120 lacking C3d moieties. pbs 3-6 T cell receptor gamma constant 1 Homo sapiens 12-27 16051303-6 2005 In PBS, the gp120DeltaC1/C5(C3d)(2) proteins are able to elicit gp120 binding antibodies more efficiently than gp120 lacking C3d moieties. pbs 3-6 endogenous retrovirus group K member 13 Homo sapiens 28-31 16051303-6 2005 In PBS, the gp120DeltaC1/C5(C3d)(2) proteins are able to elicit gp120 binding antibodies more efficiently than gp120 lacking C3d moieties. pbs 3-6 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 12-17 16051303-6 2005 In PBS, the gp120DeltaC1/C5(C3d)(2) proteins are able to elicit gp120 binding antibodies more efficiently than gp120 lacking C3d moieties. pbs 3-6 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 64-69 16051303-8 2005 In the presence of the Ribi, which contains the TLR-4 agonist monophospholipid A (MPL), antibodies elicited by the gp120DeltaC1/C5(C3d)(2) were of higher titer than those elicited by the identical protein in PBS. pbs 208-211 toll like receptor 4 Homo sapiens 48-53 16051303-8 2005 In the presence of the Ribi, which contains the TLR-4 agonist monophospholipid A (MPL), antibodies elicited by the gp120DeltaC1/C5(C3d)(2) were of higher titer than those elicited by the identical protein in PBS. pbs 208-211 T cell receptor gamma constant 1 Homo sapiens 115-130 16051303-8 2005 In the presence of the Ribi, which contains the TLR-4 agonist monophospholipid A (MPL), antibodies elicited by the gp120DeltaC1/C5(C3d)(2) were of higher titer than those elicited by the identical protein in PBS. pbs 208-211 endogenous retrovirus group K member 13 Homo sapiens 131-134 16143573-1 2005 beta-Lactoglobulin (beta-LG) denatured with 6 M guanidine hydrochloride (GdnHCl) containing a reducing agent and subsequently dialysed against phosphate-buffered saline (PBS) resulted in incomplete refolding of this protein despite the fact that the biological activity for retinol-binding was recovered to almost the same degree as that of the native molecule [Hattori, M., Ametani, A., Katakura, Y., Shimizu, M., Kaminogawa, S. J., Biol. pbs 170-173 beta-lactoglobulin Bos taurus 0-18 16143573-5 2005 We reveal in this present work that complete refolding could be attained by diluting denatured beta-LG with PBS containing a reducing agent, before slow reoxidation of the sulfhydryl groups upon dialysis for gradient removal of the reducing agent in 6 steps. pbs 108-111 beta-lactoglobulin Bos taurus 95-102 16135898-6 2005 RESULTS: Of 18 cats vaccinated with subtype B HIV-1 (HIV-1LAI/LAV, HIV-1UCD1) p24 in Ribi/cytokine adjuvant 14 (78%) were protected against FIV challenges (subtype Agag and Bgag) that infected all 15 adjuvant- or PBS-immunized cats. pbs 213-216 transmembrane p24 trafficking protein 2 Homo sapiens 78-81 15849810-10 2005 RESULTS: Cells treated with Ad/TRAIL-F/RGD and Ad/gTRAIL showed a significantly reduced cell viability in comparison to PBS and Ad/CMV-GFP treatment in both cell lines. pbs 120-123 TNF superfamily member 10 Homo sapiens 31-36 15909296-4 2005 Impregnation of EGF and bFGF into the dried hydrogels was carried out by use of phosphate buffered saline solution (PBS, pH = 7.4) containing 0.5 microg mL(-1) EGF and 0.1 microg mL(-1) bFGF, respectively. pbs 116-119 epidermal growth factor like 1 Rattus norvegicus 16-19 15909296-4 2005 Impregnation of EGF and bFGF into the dried hydrogels was carried out by use of phosphate buffered saline solution (PBS, pH = 7.4) containing 0.5 microg mL(-1) EGF and 0.1 microg mL(-1) bFGF, respectively. pbs 116-119 fibroblast growth factor 2 Rattus norvegicus 24-28 15967811-6 2005 In contrast, eIF3, G3BP, eIF4G, and PABP-1 are restricted to SGs, whereas DCP1a and 2 are confined to PBs. pbs 102-105 decapping mRNA 1A Homo sapiens 74-85 15967811-7 2005 SGs and PBs also can harbor the same species of mRNA and physically associate with one another in vivo, an interaction that is promoted by the related mRNA decay factors TTP and BRF1. pbs 8-11 BRF1 RNA polymerase III transcription initiation factor subunit Homo sapiens 178-182 16039282-10 2005 Of the tested cytokines, only MCP-1 stimulates arteriogenesis, as assessed by collateral conductance measurements ((ml/(min 100 mmHg)): PBS, 50.70+/-5.15; MCP-1, 216.30+/-12.30; IL-8, 58.91+/-5.56; NAP-2, 66.83+/-8.72; Ltn, 52.80+/-5.37) and angiographic findings. pbs 136-139 C-C motif chemokine 2 Oryctolagus cuniculus 30-35 15905702-5 2005 RESULTS: Rats with TNBS-induced colitis given human HGF showed a significant reduction in colonic ulcer coverage and large intestinal shortening compared with those treated with PBS. pbs 178-181 hepatocyte growth factor Homo sapiens 52-55 15759128-5 2005 PBs, containing mainly three-repeat (3R) tau, were positive for CS but not for GAL and its affinity to TR was, at most, weak. pbs 0-3 microtubule associated protein tau Homo sapiens 41-44 15541978-15 2004 In addition, Adeno-beta2AR therapy enhanced beta agonist stimulated LV dP/dtmax (5348+/-121 vs 4337+/-405 mmHg/s; P<0.05) and heart rate (209+/-6.9 vs 173+/-11.0 bpm; P<0.05), and reduced LVEDP (2.1+/-0.4 vs 6.4+/-1.8 mmHg; P<0.05) compared to PBS treatment. pbs 253-256 adrenoceptor beta 2 Homo sapiens 19-26 15640846-3 2005 The Plks have well conserved 30-amino-acid elements, designated polo boxes (PBs), located in their carboxyl-termini, which with their flanking regions constitute a functional Polo-box domain (PBD). pbs 76-79 polo Drosophila melanogaster 175-179 15527848-10 2004 A proviral genome containing a PBS complementary to tRNAHis that encodes an siRNA molecule complementary to the wild-type PBS under control of a U6 promoter within the nef gene was as infectious as the parent HIV-1 genome containing no insert in nef. pbs 31-34 Nef Human immunodeficiency virus 1 168-171 15527848-12 2004 At later times of infection, viruses with the PBS complementary to tRNAHis and the siRNA exhibited a rapid increase in p24 antigen in the culture. pbs 46-49 transmembrane p24 trafficking protein 2 Homo sapiens 119-122 15744783-7 2005 Mucin-treated composites showed generally lower methylene blue staining compared to serum and PBS groups. pbs 94-97 LOC100508689 Homo sapiens 0-5 15892613-7 2005 Incubation of GRY (25 microM) for 4-14 days at 37 degrees C in phosphate buffered saline (PBS), pH 7.0, or in PBS containing urea (0.8 M), pH 6.5, leads to amyloid fibril formation. pbs 90-93 trafficking protein particle complex subunit 11 Homo sapiens 14-17 15892613-7 2005 Incubation of GRY (25 microM) for 4-14 days at 37 degrees C in phosphate buffered saline (PBS), pH 7.0, or in PBS containing urea (0.8 M), pH 6.5, leads to amyloid fibril formation. pbs 110-113 trafficking protein particle complex subunit 11 Homo sapiens 14-17 15640846-3 2005 The Plks have well conserved 30-amino-acid elements, designated polo boxes (PBs), located in their carboxyl-termini, which with their flanking regions constitute a functional Polo-box domain (PBD). pbs 76-79 polo Drosophila melanogaster 64-68 15567301-5 2005 Both prodrugs were converted into CsA within the first minute in the presence of rabbit tears with rate constants of k=5.9x10(-3)min(-1) and k=3.8x10(-3)min(-1), respectively, for UNIL088 and UNIL089, whereas chemical conversion in PBS was negligible (k=0.5x10(-3)min(-1) for both molecules). pbs 232-235 ERCC excision repair 8, CSA ubiquitin ligase complex subunit Homo sapiens 34-37 17038834-6 2005 Relative to vaccination with either gB or pp65 pDNA delivered alone, vaccination with gB and pp65 pDNAs delivered together in phosphate-buffered saline (PBS) elicited reduced antibody and T cell responses to each antigen. pbs 153-156 lymphocyte cytosolic protein 1 Mus musculus 93-97 15123771-11 2004 In contrast, plasma MIP-2 was significantly elevated at both doses compared with the PBS-treated controls. pbs 85-88 chemokine (C-X-C motif) ligand 2 Mus musculus 20-25 15519362-4 2004 By semiquantitative RT-PCR analysis, long-lasting enhanced expression of the beta-CGRP mRNA was shown in the lungs of the AI rats (14.5-fold enhancement at 6 hr, 8.1-fold at 24 hr, and 3.7-fold at 120 hr after OVA-challenge compared to the level in the lungs of phosphate-buffered saline (PBS)-challenged control rats). pbs 289-292 calcitonin-related polypeptide alpha Rattus norvegicus 82-86 15241613-10 2004 Compared to the PBS-treated mice, numbers of CD3, CD11b, GR-1 and F4/80-positive cells were reduced in the DMF group of mice. pbs 16-19 CD3 antigen, epsilon polypeptide Mus musculus 45-48 15241613-10 2004 Compared to the PBS-treated mice, numbers of CD3, CD11b, GR-1 and F4/80-positive cells were reduced in the DMF group of mice. pbs 16-19 integrin subunit alpha M Homo sapiens 50-55 15093220-3 2004 The characterization of the SOD electrodes showed a quasi-reversible electrochemical redox behavior with a formal potential of 80 + 5 mV (versus SCE) in 50 mmol l(-1) phosphate buffer solution (PBS), pH 7.0. pbs 194-197 superoxide dismutase 1 Homo sapiens 28-31 15147343-11 2004 The frequencies of CD4(+)CD25(+) regulatory T cells in the spleen were significantly decreased in neonatal thymectomized mice administered with poly I:C compared to PBS-treated neonatal thymectomized mice (P < 0.01). pbs 165-168 CD4 antigen Mus musculus 19-22 15190942-9 2004 Concentrations of lactoferrin in secretions were increased by rboGM-CSF and rbolL-1beta compared with control PBS quarters. pbs 110-113 lactotransferrin Bos taurus 18-29 15071458-10 2004 Message analysis in whole-graft lysates at 1 week showed that MCP-1 message expression increased in the Lip-Clod group compared with the PBS group (P=.02), but no significant differences among groups for TGF-beta message levels. pbs 137-140 C-C motif chemokine ligand 2 Rattus norvegicus 62-67 15086694-11 2004 From the 3 months post-release to the 3 months post-PBS listing, a period of 13 months, COX-2 use in rheumatology patients increased from 18 to 57%. pbs 52-55 prostaglandin-endoperoxide synthase 2 Homo sapiens 88-93 15144568-3 2004 In the SW620 xenograft tumor model, various treatment groups showed marked differences at week 11, with the tumor volume for the phosphate-buffered saline (PBS) treatment group >1700 mm3, for 5-FU > 1300 mm3, for ONYX015 1051.3 mm3, for ZD55-hTRAIL 600.05 mm3, and for ZD55-hTRAIL plus 5-FU 230.2 mm3. pbs 156-159 TNF superfamily member 10 Homo sapiens 248-254 15144568-3 2004 In the SW620 xenograft tumor model, various treatment groups showed marked differences at week 11, with the tumor volume for the phosphate-buffered saline (PBS) treatment group >1700 mm3, for 5-FU > 1300 mm3, for ONYX015 1051.3 mm3, for ZD55-hTRAIL 600.05 mm3, and for ZD55-hTRAIL plus 5-FU 230.2 mm3. pbs 156-159 TNF superfamily member 10 Homo sapiens 280-286 15093181-5 2004 MDA-7/IL-24 inhibited migration and invasion by down-regulating the production of phosphatidylinositol 3-kinase/protein kinase B, focal adhesion kinase, and matrix metalloproteinase-2 and -9 relative to PBS and Ad-Luc. pbs 203-206 interleukin 24 Homo sapiens 0-5 15093181-5 2004 MDA-7/IL-24 inhibited migration and invasion by down-regulating the production of phosphatidylinositol 3-kinase/protein kinase B, focal adhesion kinase, and matrix metalloproteinase-2 and -9 relative to PBS and Ad-Luc. pbs 203-206 interleukin 24 Homo sapiens 6-11 14654682-2 2003 The O3 stem and three stem-loops (O3SLa, O3SLb and O3SLc) form the minimal packaging signal that is located downstream of the primer binding site (PBS). pbs 147-150 Src like adaptor Homo sapiens 36-39 14654682-8 2003 The PBS/O3SLa interaction may be formed in vivo since the sequences are highly conserved in ASLV strains. pbs 4-7 Src like adaptor Homo sapiens 10-13 14654682-9 2003 The PBS/O3SLa interaction may regulate the processes of primer tRNA annealing, packaging and initiation of Gag translation through its involvement in leader tertiary structure. pbs 4-7 Src like adaptor Homo sapiens 10-13 12565895-2 2003 HIV-1 reverse transcription is initiated when its cognate primer tRNA (Lys-3) binds to the primer binding site (PBS) of the viral RNA template. pbs 112-115 mitochondrially encoded tRNA glycine Homo sapiens 65-76 14610254-8 2003 In rats pretreated with saline and stimulated with leptin (saline/LEPTIN group), food intake diminished to about 50% of that of the saline/PBS group (P < 0.005). pbs 139-142 leptin Rattus norvegicus 51-57 12809772-2 2003 About 20% of the FGF-2molecules were released from the FGF-2-incorporated chitosan hydrogel into phosphate buffered saline (PBS) within 1 day, after which no further significant release occurred under in vitro non-degradation conditions of the hydrogel. pbs 124-127 fibroblast growth factor 2 Mus musculus 17-22 12809772-2 2003 About 20% of the FGF-2molecules were released from the FGF-2-incorporated chitosan hydrogel into phosphate buffered saline (PBS) within 1 day, after which no further significant release occurred under in vitro non-degradation conditions of the hydrogel. pbs 124-127 fibroblast growth factor 2 Mus musculus 55-60 12954204-3 2003 We have previously described a mutant HIV-1 with a primer binding site (PBS) complementary to yeast tRNA(Phe) (psHIV-Phe) that relies on transfection of yeast tRNA(Phe) for infectivity. pbs 72-75 mitochondrially encoded tRNA glycine Homo sapiens 100-109 12954204-3 2003 We have previously described a mutant HIV-1 with a primer binding site (PBS) complementary to yeast tRNA(Phe) (psHIV-Phe) that relies on transfection of yeast tRNA(Phe) for infectivity. pbs 72-75 mitochondrially encoded tRNA glycine Homo sapiens 159-168 12954204-7 2003 Increasing the cytoplasmic levels of tRNA(Phe) resulted in increased encapsidation of tRNA(Phe) in viruses with a PBS complementary to tRNA(Phe) (psHIV-Phe) or tRNA(Lys,3) (wild-type HIV-1). pbs 114-117 mitochondrially encoded tRNA glycine Homo sapiens 37-46 12954204-7 2003 Increasing the cytoplasmic levels of tRNA(Phe) resulted in increased encapsidation of tRNA(Phe) in viruses with a PBS complementary to tRNA(Phe) (psHIV-Phe) or tRNA(Lys,3) (wild-type HIV-1). pbs 114-117 mitochondrially encoded tRNA glycine Homo sapiens 86-95 12954204-7 2003 Increasing the cytoplasmic levels of tRNA(Phe) resulted in increased encapsidation of tRNA(Phe) in viruses with a PBS complementary to tRNA(Phe) (psHIV-Phe) or tRNA(Lys,3) (wild-type HIV-1). pbs 114-117 mitochondrially encoded tRNA glycine Homo sapiens 86-95 12914799-3 2003 In our approach for the analysis of the composition of tau inclusions, we detected the intense binding of anti-diacylglycerol kinase-zeta (DGK-zeta) antibodies to Pick bodies (PBs), which represent tau inclusions in Pick"s disease. pbs 176-179 diacylglycerol kinase zeta Homo sapiens 106-137 12914799-3 2003 In our approach for the analysis of the composition of tau inclusions, we detected the intense binding of anti-diacylglycerol kinase-zeta (DGK-zeta) antibodies to Pick bodies (PBs), which represent tau inclusions in Pick"s disease. pbs 176-179 diacylglycerol kinase zeta Homo sapiens 139-147 12914799-3 2003 In our approach for the analysis of the composition of tau inclusions, we detected the intense binding of anti-diacylglycerol kinase-zeta (DGK-zeta) antibodies to Pick bodies (PBs), which represent tau inclusions in Pick"s disease. pbs 176-179 protein interacting with PRKCA 1 Homo sapiens 163-167 12914799-6 2003 Our results suggest that sequestration of the N-terminal fragment of proSAAS in intracellular PBs may cause a functional disturbance of neurons in Pick"s disease. pbs 94-97 proprotein convertase subtilisin/kexin type 1 inhibitor Homo sapiens 69-76 12125080-6 2002 Animals receiving GDNF treatment showed significant improvement over phosphate-buffered saline (PBS)-treated controls on the Basso Beattie Bresnahan (BBB) locomotor rating scale (P < 0.01-0.001). pbs 96-99 glial cell derived neurotrophic factor Rattus norvegicus 18-22 12532154-15 2003 were significantly increased to the level seen in the saline/PBS group at 12 and 24 h time points (P<0.05, and P<0.005 vs the saline/leptin group, respectively). pbs 61-64 leptin Rattus norvegicus 139-145 12881637-2 2002 Using two viral RNA probes, one overlapping the primer-binding site (PBS) and the other representing the ribosomal frameshifting signal (FS) of HIV-1 RNA, we found that recombinant full-length Nef protein (NefLAI) increased the affinity of reverse transcriptase (RT) for RNA in vitro, and interacted directly with RT in protein co-precipitation assays. pbs 69-72 Nef Human immunodeficiency virus 1 193-196 12410393-3 2002 Numerous PBs were distributed widely, and were occasionally immunoreactive for alpha-S and beta-S, but not for gamma-S in all three cases. pbs 9-12 synuclein alpha Homo sapiens 79-86 12410393-6 2002 These findings suggest that alpha-S and beta-S are up-regulated in the neuronal perikarya but they are not incorporated into the constituent filaments of PBs, and that the preferential distribution of alpha-S- and beta-S-positive PBs in the dentate gyrus may represent the cellular response to PB formation in this particular system. pbs 230-233 synuclein alpha Homo sapiens 201-208 12428251-9 2002 Lower steady-state messenger RNA (mRNA) levels for TNFalpha, interferon-gamma (IFNgamma), IL-18, and IL-6 were observed in the joints of anti-C5-treated mice, and for IFNgamma and IL-6 in mice receiving Crry-Ig, all in comparison with PBS-treated mice. pbs 235-238 hemolytic complement Mus musculus 142-144 27407422-4 2002 Taking PBS positivity as a gold standard of diagnostic criteria, OCT had a sensitivity of 83% and specificity of 86% with a high positive predictive value of 88% as compared to ALT which had a lower sensitivity of 55% and specificity of 80%. pbs 7-10 ornithine transcarbamylase Homo sapiens 65-68 27407422-5 2002 The clinical response rate in PBS negative cases of fever having high OCT level was 83% as compared to 35% in cases with normal OCT level, making OCT a good surrogate marker of malaria. pbs 30-33 ornithine transcarbamylase Homo sapiens 70-73 12151304-8 2002 Furthermore, an adenovirus encoding the cystic fibrosis transmembrane regulator (CFTR) gene (AdCFTR) formulated in TS was more efficient in correcting the chloride transport defect in cystic fibrosis airway epithelia than AdCFTR formulated in PBS. pbs 243-246 CF transmembrane conductance regulator Homo sapiens 40-79 12151304-8 2002 Furthermore, an adenovirus encoding the cystic fibrosis transmembrane regulator (CFTR) gene (AdCFTR) formulated in TS was more efficient in correcting the chloride transport defect in cystic fibrosis airway epithelia than AdCFTR formulated in PBS. pbs 243-246 CF transmembrane conductance regulator Homo sapiens 81-85 12483648-8 2002 Similarly, the percentage of the tubules at stage III (containing round spermatids) in the hCG-treated group was significantly increased, from 25% to 71%, compared with the PBS-treated group (P <.01). pbs 173-176 chorionic gonadotropin subunit beta 5 Homo sapiens 91-94 12512896-4 2002 Group 1 animals (n = 5) underwent direct placement of FGF-1 in phosphate buffered saline (PBS) (20 pg/mL) soaked Gelfoam pledgets to the right round window membrane. pbs 90-93 fibroblast growth factor 1 Cavia porcellus 54-59 12125080-7 2002 GDNF treatment increased the remaining neuronal fibers with calcitonin gene-related peptide, neurofilament, and growth-associated protein 43 immunoreactivity in injured spinal tissues compared with PBS-treated controls. pbs 198-201 glial cell derived neurotrophic factor Rattus norvegicus 0-4 12003495-1 2002 Reverse transcription of the HIV-1 RNA genome is primed by the cellular tRNA(lys3) molecule that anneals to a complementary sequence in the viral genome, the primer-binding site (PBS). pbs 179-182 mitochondrially encoded tRNA glycine Homo sapiens 72-81 12010247-3 2002 They were then treated by an intracavernosal injection with 4 microg of VEGF in phosphate-buffered saline (PBS) or PBS alone. pbs 107-110 vascular endothelial growth factor A Rattus norvegicus 72-76 12010247-7 2002 RESULTS: Microarray analysis detected nNOS, eNOS and iNOS at very low expression levels in PBS-treated rats; expression levels were higher for eNOS and iNOS in all VEGF-treated rats. pbs 91-94 nitric oxide synthase 1 Rattus norvegicus 38-42 12010247-7 2002 RESULTS: Microarray analysis detected nNOS, eNOS and iNOS at very low expression levels in PBS-treated rats; expression levels were higher for eNOS and iNOS in all VEGF-treated rats. pbs 91-94 nitric oxide synthase 3 Rattus norvegicus 44-48 12010247-7 2002 RESULTS: Microarray analysis detected nNOS, eNOS and iNOS at very low expression levels in PBS-treated rats; expression levels were higher for eNOS and iNOS in all VEGF-treated rats. pbs 91-94 nitric oxide synthase 2 Rattus norvegicus 53-57 11997159-12 2002 The streptococcal adherence rates to pharyngeal epithelial cells were significantly decreased by pretreatment with pharyngeal washings from the mice immunized with LTA and CT-B as compared with pretreatment with those from either mice with PBS or mice with LTA alone. pbs 240-243 phosphate cytidylyltransferase 1, choline, beta isoform Mus musculus 172-176 12133417-9 2002 (3) Serum VEGF level in SKOV3/Rg3 group [(14.6 +/- 0.7) pg/ml] was lower significantly than those of SKOV3 group and SKOV3/PBS group [(18.5 +/- 2.1) and (20.5 +/- 1.7) pg/ml, respectively, P < 0.05]. pbs 123-126 vascular endothelial growth factor A Mus musculus 10-14 12091442-6 2002 RESULTS: Upregulation of TRX and HNE-modified protein, decrease of GSH, and nuclear translocation of NF-kappaB were noted after light exposure in PBS-treated mice. pbs 146-149 thioredoxin 1 Mus musculus 25-28 11833745-6 2002 Moreover, A beta-induced cytotoxicity assays showed A beta incubated in PBS to be more cytotoxic than that incubated in PB. pbs 72-75 amyloid beta precursor protein Homo sapiens 10-16 11810176-1 2002 In corticobasal degeneration (CBD), tau-positive cytoplasmic inclusions resembling Pick bodies (PBs) appear in the cerebral cortex. pbs 96-99 microtubule associated protein tau Homo sapiens 36-39 11810176-1 2002 In corticobasal degeneration (CBD), tau-positive cytoplasmic inclusions resembling Pick bodies (PBs) appear in the cerebral cortex. pbs 96-99 protein interacting with PRKCA 1 Homo sapiens 83-87 11810176-2 2002 Tau immunoreactivity in PBs is expressed mainly on filamentous elements, whereas that of PB-like inclusions in CBD is expressed on granules, which are densely packed mainly in the periphery of inclusions. pbs 24-27 microtubule associated protein tau Homo sapiens 0-3 11810176-3 2002 PBs are clearly detectable by conventional Bodian silver impregnation but negative for the Gallyas-Braak (G-B) method and for PS262, which recognizes phosphorylation at Ser 262 of the entire tau sequence. pbs 0-3 microtubule associated protein tau Homo sapiens 191-194 11810176-4 2002 Almost all PBs are negative for Ex10, which recognizes 4-repeat tau specifically. pbs 11-14 microtubule associated protein tau Homo sapiens 64-67 11791902-4 2002 When collagen sponges incorporating 125I-labeled TGF-beta1 were placed in phosphate-buffered saline (PBS) solution at 37 degrees C, a small amount of TGF-beta1 was released for the first hour, but no further release was observed thereafter, irrespective of the amount of cross-linking time the sponges had received. pbs 101-104 LOW QUALITY PROTEIN: transforming growth factor beta-1 Oryctolagus cuniculus 49-58 11791902-4 2002 When collagen sponges incorporating 125I-labeled TGF-beta1 were placed in phosphate-buffered saline (PBS) solution at 37 degrees C, a small amount of TGF-beta1 was released for the first hour, but no further release was observed thereafter, irrespective of the amount of cross-linking time the sponges had received. pbs 101-104 LOW QUALITY PROTEIN: transforming growth factor beta-1 Oryctolagus cuniculus 150-159 11833745-6 2002 Moreover, A beta-induced cytotoxicity assays showed A beta incubated in PBS to be more cytotoxic than that incubated in PB. pbs 72-75 amyloid beta precursor protein Homo sapiens 52-58 11497252-3 2001 Bone morphogenetic protein-2 (BMP-2) has recently been proposed to be involved in the calcification of tumor cells and recent electron microscopic studies demonstrated the presence of type IV collagen in PBs. pbs 204-207 bone morphogenetic protein 2 Homo sapiens 0-28 11580244-2 2001 In the case of human immunodeficiency virus type 1 (HIV-1), the 3" 18 nucleotides of human tRNA(Lys,3) are annealed to a complementary sequence on the RNA genome known as the primer binding site (PBS). pbs 196-199 mitochondrially encoded tRNA glycine Homo sapiens 91-101 11580244-8 2001 A mutant form of NC (SSHS NC), which lacks the zinc finger structures, is able to anneal tRNA(Lys,3) efficiently to the PBS, and to destabilize the tRNA tertiary core, albeit less effectively than wild-type NC. pbs 120-123 mitochondrially encoded tRNA glycine Homo sapiens 89-99 11559799-2 2001 tRNA(Lys)(3) interacts directly with HIV-1 reverse transcriptase (RT), is packaged into viral particles, and anneals to the primer-binding site (PBS) of the HIV-1 genome in order to initiate reverse transcription. pbs 145-148 mitochondrially encoded tRNA glycine Homo sapiens 0-11 11559799-3 2001 Residue A58 of tRNA(Lys)(3), which lies outside the PBS-complementary region, is posttranscriptionally methylated to form 1-methyladenosine 58 (M(1)A58). pbs 52-55 mitochondrially encoded tRNA glycine Homo sapiens 15-26 11433020-1 2001 Human immunodeficiency virus type 2 (HIV-2) reverse transcription is initiated from cellular tRNA(Lys3) partially annealed to the RNA viral genome at the primer binding site (PBS). pbs 175-178 mitochondrially encoded tRNA glycine Homo sapiens 93-102 11433020-7 2001 In addition to the canonical contacts between the viral PBS and the 3" end acceptor stem of tRNA(Lys3), we identified two additional interacting domains: (i) the U-rich region of the anticodon loop with the A-rich sequence of the internal loop within the U5-prePBS region; (ii) nucleotides 48-54 from the TPsiC domain of tRNA(Lys3) and the 240-247 region of viral U5-RNA. pbs 56-59 mitochondrially encoded tRNA glycine Homo sapiens 92-101 11433020-7 2001 In addition to the canonical contacts between the viral PBS and the 3" end acceptor stem of tRNA(Lys3), we identified two additional interacting domains: (i) the U-rich region of the anticodon loop with the A-rich sequence of the internal loop within the U5-prePBS region; (ii) nucleotides 48-54 from the TPsiC domain of tRNA(Lys3) and the 240-247 region of viral U5-RNA. pbs 56-59 mitochondrially encoded tRNA glycine Homo sapiens 321-330 11413227-3 2001 The fact that the four-line spectrum obtained for the Abeta/PBN in PBS was completely abolished in the presence of the iron-chelating agent Desferal demonstrated the observed four-line spectrum to be iron-dependent. pbs 67-70 amyloid beta precursor protein Homo sapiens 54-59 11413227-5 2001 Both a thioflavine-T (Th-T) fluorometric assay and circular dichroism (CD) spectroscopy showed the amyloid fibril formation of Abeta in PBS to be much higher than that of Abeta in PB. pbs 136-139 amyloid beta precursor protein Homo sapiens 127-132 11413227-6 2001 Moreover, Abeta-induced cytotoxicity assays showed Abeta incubated in PBS to be more cytotoxic than that incubated in PB. pbs 70-73 amyloid beta precursor protein Homo sapiens 10-15 11413227-6 2001 Moreover, Abeta-induced cytotoxicity assays showed Abeta incubated in PBS to be more cytotoxic than that incubated in PB. pbs 70-73 amyloid beta precursor protein Homo sapiens 51-56 11682699-4 2001 Exposure to 400, 500, or 600 mOsm phosphate-buffered saline (PBS) caused cell shrinkage and an osmolality-dependent increase in p38 activity to 175%, 409%, or 518%, respectively, compared with cells maintained in control conditions (290 mOsm). pbs 61-64 mitogen activated protein kinase 14 Rattus norvegicus 128-131 11682699-5 2001 Likewise, hyposmotic conditions ranging from 250 to 57 mOsm PBS caused the same activation of p38 (approximately 300% of the control value within 10 min). pbs 60-63 mitogen activated protein kinase 14 Rattus norvegicus 94-97 11672586-7 2001 Phosphate-buffered saline (PBS), instead of plasma, was used to obtain the initial level of coated undigested VWF. pbs 27-30 von Willebrand factor Homo sapiens 110-113 11497252-4 2001 Based on this evidence, we postulated a possibe role for BMP-2 and type IV collagen in the formation of PBs in ovarian cancer. pbs 104-107 bone morphogenetic protein 2 Homo sapiens 57-62 11497252-10 2001 PBs-forming NK-211 was intensively positive for both BMP-2 and type IV collagen. pbs 0-3 bone morphogenetic protein 2 Homo sapiens 53-58 11497252-13 2001 In PBs themselves, 100% (20 out of 20) positivity for BMP-2 and 80% (16 out of 20) for type IV collagen was shown. pbs 3-6 bone morphogenetic protein 2 Homo sapiens 54-59 11497252-14 2001 These results raise the possibility that BMP-2 and type IV collagen-producing slow growing tumor cells form PBs in ovarian cancer. pbs 108-111 bone morphogenetic protein 2 Homo sapiens 41-46 11312362-1 2001 A mutant human immunodeficiency virus type 1 (HIV-1) with a primer binding site (PBS) complementary to yeast tRNA(Phe) (psHIV-Phe), which relies on exogenous yeast tRNA(Phe) as reverse transcription primer, was used to investigate elements in the tRNA acceptor stem and T(Psi)C stem-loop required for the tRNA primer selection and use in HIV-1 replication. pbs 81-84 mitochondrially encoded tRNA glycine Homo sapiens 109-118 11312362-1 2001 A mutant human immunodeficiency virus type 1 (HIV-1) with a primer binding site (PBS) complementary to yeast tRNA(Phe) (psHIV-Phe), which relies on exogenous yeast tRNA(Phe) as reverse transcription primer, was used to investigate elements in the tRNA acceptor stem and T(Psi)C stem-loop required for the tRNA primer selection and use in HIV-1 replication. pbs 81-84 mitochondrially encoded tRNA glycine Homo sapiens 164-173 11166274-4 2001 RESULTS: Collateral conductance index significantly increased when MCP-1 treatment started directly after femoral artery ligation (acute occlusion: 0.94+/-0.19; without occlusion: 168.56+/-15.99; PBS: 4.10+/-0.48; MCP-1: 33.96+/-1.76 ml/min/100 mmHg). pbs 196-199 C-C motif chemokine 2 Oryctolagus cuniculus 67-72 11085758-7 2000 Low CD4+ counts were consistently associated with more Health and Depression-Anxiety symptoms on the PBS. pbs 101-104 CD4 molecule Homo sapiens 4-7 11887856-5 2001 During dialysis with PBS+G, the inflammatory response was suppressed as compared with the first dialysis with PBS (cell count, p < 0.001; Ne:Ma, p < 0.05; TNFalpha, p < 0.001; total protein, p < 0.001). pbs 21-24 tumor necrosis factor Rattus norvegicus 161-169 11134546-3 2001 Here we report on the activity of NF-kappaB in cells exposed to subcytotoxic concentrations of smoke-bubbled PBS. pbs 109-112 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 34-43 11134073-13 2000 Analysis of the deduced amino acid sequence of actopaxin reveals a 42-kD protein with two calponin homology domains and a paxillin-binding subdomain (PBS). pbs 150-153 parvin alpha Homo sapiens 47-56 11134073-13 2000 Analysis of the deduced amino acid sequence of actopaxin reveals a 42-kD protein with two calponin homology domains and a paxillin-binding subdomain (PBS). pbs 150-153 paxillin Homo sapiens 122-130 11134073-19 2000 An actopaxin PBS mutant incapable of binding paxillin in vitro cannot target to focal adhesions when expressed in fibroblasts. pbs 13-16 parvin alpha Homo sapiens 3-12 11134073-19 2000 An actopaxin PBS mutant incapable of binding paxillin in vitro cannot target to focal adhesions when expressed in fibroblasts. pbs 13-16 paxillin Homo sapiens 45-53 11033124-5 2000 RESULTS: The levels of constitutive expression of MMP-2 and TIMP-1 mRNA persisted, whereas MMP-9 mRNA in the PBS-treated side was expressed temporarily after surgical removal. pbs 109-112 matrix metalloproteinase-9 Oryctolagus cuniculus 91-96 10766870-2 2000 The vRNA and the primer tRNA(3)(Lys) form several intermolecular interactions in addition to annealing of the primer 3" end to the primer binding site (PBS). pbs 152-155 vault RNA 1-1 Homo sapiens 4-8 10871360-7 2000 Almost all mismatch-deficient cell colonies analyzed (cell lines HCT 116 and PMS2-/-) contained both the wild-type and mutated PBS, therefore, mismatches within retroviral double-strand DNA could not be repaired by the mismatch-deficient cells. pbs 127-130 PMS1 homolog 2, mismatch repair system component Homo sapiens 77-81 10931921-1 2000 Reverse transcription of human immunodeficiency virus type-1 is primed by cellular tRNA(Lys3), which is selectively packaged into viral particles where it is bound at its 3" terminus to a complementary sequence of viral RNA termed the primer binding site (PBS). pbs 256-259 mitochondrially encoded tRNA glycine Homo sapiens 83-92 10774791-5 2000 Morphometric analysis of serial tissue sections at 4 weeks after vascular injury showed that in 75% of the EGF-Gen-treated mice, the maximal stenosis index was only 0.44 +/- 0.13, whereas in 75% of phosphate-buffered saline (PBS)-treated mice, the maximal stenosis index was 1.20 +/- 0.25. pbs 225-228 epidermal growth factor Mus musculus 107-110 10737539-12 2000 CONCLUSIONS: Suppression of PPF and impairment of the potentiation by PBS in CA1 hippocampal neurons was observed in castrated male mice and these changes were reversed by testosterone injection. pbs 70-73 carbonic anhydrase 1 Mus musculus 77-80 10670033-9 1999 Using the citric acid technique the average concentration of RANTES in middle turbinates was 1.3 ng/mg, in inferior turbinates 1.6 ng/mg and in polyps 2.6 ng/mg tissue, using the PBS technique respectively 0.6 ng/mg, 0.5 ng/mg and 0.8 ng/mg tissue. pbs 179-182 C-C motif chemokine ligand 5 Homo sapiens 61-67 10661504-6 2000 AR-LI was significantly higher on the BDNF-treated side than on the contralateral side treated with phosphate-buffered saline (PBS) for all three doses of BDNF (1.45, 2.9, and 5.8 mg/ml) and was higher than in rats treated bilaterally with PBS. pbs 127-130 brain-derived neurotrophic factor Rattus norvegicus 155-159 10661504-6 2000 AR-LI was significantly higher on the BDNF-treated side than on the contralateral side treated with phosphate-buffered saline (PBS) for all three doses of BDNF (1.45, 2.9, and 5.8 mg/ml) and was higher than in rats treated bilaterally with PBS. pbs 240-243 brain-derived neurotrophic factor Rattus norvegicus 38-42 10535404-5 1999 In two separate experiments, a single ip injection of 200 microg/g body weight (BW) hFSH-beta-(90-95) in phosphate buffered saline (PBS, vehicle) administered to mice on day 28 delayed first vaginal estrus by 3 days in 50% (4/8) and 62.5% (6/8) when compared to mice given vehicle alone on day 28. pbs 132-135 follicle stimulating hormone subunit beta Homo sapiens 84-93 11721480-4 1999 RESULTS: The IL-8 treatment significantly enhanced airway responsiveness to histamine in a dose-dependent manner (P < 0.05 or P < 0.01) and induced a significant influx of neutrophils in BALF (P < 0.01), and a great number of neutrophils were seen within the airway wall, but not within the control animals treated with phosphate buffered saline (PBS). pbs 356-359 interleukin-8 Cavia porcellus 13-17 10951865-7 1999 Correlation analysis (Pearson"s correlation coefficient and Mann-Whitney"s test, p0.05) revealed in both groups a significant relationship of both CAM assessed in PBS and BMA (sVCAM-1 p-0.0000 and p-0.012, sICAM-1 p-0.0000 and p-0.0011). pbs 163-166 calmodulin 3 Homo sapiens 147-150 10951865-10 1999 In the group of 39 patients examined when the diagnosis of MM was made a relationship was found of sVCAM-1 in PBS to S-B2M) (p - 0.0000), S-TK (p-0.0000) and to S-creatinine (p -0.005), in BMA there was only a relationship with B2M (p - 0.020). pbs 110-113 beta-2-microglobulin Homo sapiens 119-122 10073950-4 1999 A rapid, cellular immune response to HSP-65 was evident in mice immunized with HSP-65 or with MT but not in the animals immunized with phosphate-buffered saline (PBS) alone. pbs 162-165 heat shock protein 1 (chaperonin) Mus musculus 37-43 10524939-9 1999 RESULTS: The subcutaneous tumor mean volume at 5 weeks for the p53-specific CTL treatment group was significantly lower than for both the control CTL or the PBS group (32 mm.3 versus 185 mm.3, p = 0.04 and 32 mm.3 versus 418 mm.3, p = 0.0001). pbs 157-160 transformation related protein 53, pseudogene Mus musculus 63-66 10096624-5 1999 Administration of 1 mg per milliliter AII in PBS did not affect the viability of random flaps (1.2 x 7 cm) in this animal model. pbs 45-48 angiotensinogen Rattus norvegicus 38-41 10096624-6 1999 However, a single administration of a higher dose of AII in PBS (10 mg per milliliter) or 1 mg per milliliter AII in the CMC vehicle resulted in 67% of the grafts being fully viable at postsurgical day 12, in contrast to vehicle-treated control flaps, none of which were fully viable at day 12. pbs 60-63 angiotensinogen Rattus norvegicus 53-56 10073950-7 1999 Immunohistochemical analysis of atherosclerotic lesions from the HSP-65- and MT-immunized mice revealed infiltration of CD4 lymphocytes compared with the relatively lymphocyte-poor lesions in the PBS-treated or nonimmunized mice. pbs 196-199 heat shock protein 1 (chaperonin) Mus musculus 65-71 10205635-5 1999 Steady-state fluxes with a donor solution of phosphate-buffered saline (PBS) were 0.34 +/- 0.01 microgram/cm2h for M-TRH and 0.27 +/- 0.01 microgram/cm2h for TRH. pbs 72-75 thyrotropin releasing hormone Homo sapiens 117-120 10024591-4 1999 The number of bacteria recovered in the spleens and in the livers of rTGF-beta1-treated mice 2 and 5 days after infection was significantly smaller than that found in the same organs after phosphate-buffered saline (PBS) inoculation. pbs 216-219 transforming growth factor, beta 1 Rattus norvegicus 69-79 10024591-11 1999 Moreover, we demonstrated that 5 days after infection, the IFN-gamma titer was significantly greater in the sera of rTGF-beta-treated mice than in those of PBS-treated mice. pbs 156-159 interferon gamma Mus musculus 59-68 9635460-6 1998 The phosphate-buffered saline (PBS)-inoculated group exhibited a transient increase of IL-6 message, which indicates that this cytokine is a sensitive marker of the acute response to trauma. pbs 31-34 interleukin 6 Rattus norvegicus 87-91 9748533-5 1998 Key features are the Pick bodies (PBs) which contain an argyrophilic material. pbs 34-37 protein interacting with PRKCA 1 Homo sapiens 21-25 9686644-1 1998 Previous studies using in vitro chemical and enzyme methods demonstrated that, in addition to the primer-binding site (PBS), two regions upstream of the PBS in U5 of HIV-1 RNA interact with tRNA(Lys,3) during the initiation of reverse transcription. pbs 119-122 mitochondrially encoded tRNA glycine Homo sapiens 190-200 9686644-1 1998 Previous studies using in vitro chemical and enzyme methods demonstrated that, in addition to the primer-binding site (PBS), two regions upstream of the PBS in U5 of HIV-1 RNA interact with tRNA(Lys,3) during the initiation of reverse transcription. pbs 153-156 mitochondrially encoded tRNA glycine Homo sapiens 190-200 9452816-5 1998 Diffuse cytoplasmic immunoreactivity for apoE was found in only a few limbic system neurons without PBs in both cases. pbs 100-103 apolipoprotein E Homo sapiens 41-45 9533409-1 1998 An anti-heparan sulfate proteoglycan (HSPG) monoclonal antibody (3G10) recognized irregular round structures (IRSs) of various sizes adjacent to tau-positive intracellular Pick bodies (PBs) in the granular cell layer of the dentate gyrus and the superficial layers of the parahippocampal and other temporal gyri in Pick"s disease. pbs 185-188 syndecan 2 Homo sapiens 3-36 9533409-1 1998 An anti-heparan sulfate proteoglycan (HSPG) monoclonal antibody (3G10) recognized irregular round structures (IRSs) of various sizes adjacent to tau-positive intracellular Pick bodies (PBs) in the granular cell layer of the dentate gyrus and the superficial layers of the parahippocampal and other temporal gyri in Pick"s disease. pbs 185-188 syndecan 2 Homo sapiens 38-42 9452816-6 1998 In conclusion, it is considered that apoE may not be positively involved in the process of PB formation and that the preferential distribution of apoE-immunoreactive PBs in the limbic system may reflect the presence of certain regional factors associated with the synthesis or metabolism of apoE in this particular system. pbs 166-169 apolipoprotein E Homo sapiens 146-150 9452816-6 1998 In conclusion, it is considered that apoE may not be positively involved in the process of PB formation and that the preferential distribution of apoE-immunoreactive PBs in the limbic system may reflect the presence of certain regional factors associated with the synthesis or metabolism of apoE in this particular system. pbs 166-169 apolipoprotein E Homo sapiens 146-150 9400600-0 1997 Insights into the interaction between tRNA and primer binding site from characterization of a unique HIV-1 virus which stably maintains dual PBS complementary to tRNA(Gly) and tRNA(His). pbs 141-144 mitochondrially encoded tRNA glycine Homo sapiens 162-171 9400600-2 1997 From the analysis of the virus obtained after long-term culture, we identified an unusual proviral DNA in which the U5-PBS region contained a dual PBS complementary to tRNA(Gly) and tRNA(His), respectively, separated by a 21-nucleotide intervening sequence. pbs 119-122 mitochondrially encoded tRNA glycine Homo sapiens 168-177 9400600-8 1997 The results of this assay demonstrated that either the PBS complementary to tRNA(Gly) or tRNA(His) could be used for the initiation of reverse transcription. pbs 55-58 mitochondrially encoded tRNA glycine Homo sapiens 76-85 9396229-7 1997 The proliferation response of lymph node cells from TGF-beta 1 injected mice with IRBP-induced EAU was suppressed compared with phosphate buffered saline (PBS)-injected mice. pbs 155-158 transforming growth factor, beta 1 Mus musculus 52-62 9396229-7 1997 The proliferation response of lymph node cells from TGF-beta 1 injected mice with IRBP-induced EAU was suppressed compared with phosphate buffered saline (PBS)-injected mice. pbs 155-158 retinol binding protein 3, interstitial Mus musculus 82-86 9176516-3 1997 of Ad.RSV-hAAT were approximately four-fold higher in macrophage-depleted animals than in control animals pretreated with liposome-encapsulated phosphate-buffered saline (PBS). pbs 171-174 serpin family A member 1 Homo sapiens 10-14 10374452-4 1997 RESULTS: The IL-8 treatment significantly enhanced airway responsiveness to histamine in a dose-dependent manner (P < 0.05 or 0.01) and induced a significant influx of neutrophils in BALF (P < 0.01), and there are many neutrophils within airway wall but not control animals treated with phosphate buffered saline (PBS). pbs 320-323 interleukin-8 Cavia porcellus 13-17 9261348-4 1997 Sequence analysis of the U5 and PBS regions of integrated provirus from a cell culture infected with virus derived from pHXB2(His-AC-TGT) revealed a G-to-A change in CCTGT at nucleotide 181 after limited in vitro culture, suggesting that this nucleotide change represented an adaptation by the virus to efficiently utilize tRNA(His) to initiate reverse transcription. pbs 32-35 queuine tRNA-ribosyltransferase catalytic subunit 1 Homo sapiens 133-136 9415040-8 1997 Moreover, MCP-1 protein was found in the supernatant from homogenized granuloma tissues and the levels of MCP-1 were higher in the LPS-treated animals, while they were lower in the dexamethasone group, compared with the granulomas from the PBS-treated groups (control). pbs 240-243 C-C motif chemokine ligand 2 Rattus norvegicus 10-15 9415040-8 1997 Moreover, MCP-1 protein was found in the supernatant from homogenized granuloma tissues and the levels of MCP-1 were higher in the LPS-treated animals, while they were lower in the dexamethasone group, compared with the granulomas from the PBS-treated groups (control). pbs 240-243 C-C motif chemokine ligand 2 Rattus norvegicus 106-111 9415040-9 1997 The generation of MCP-1 was also found in minced granuloma tissue incubated for 18 hr (overnight) from treated (LPS or dexamethasone) and untreated (PBS) rats. pbs 149-152 C-C motif chemokine ligand 2 Rattus norvegicus 18-23 9415040-11 1997 Analysing blood serum from LPS, dexamethasone or PBS-treated rats, we found that MCP-1 was also present. pbs 49-52 C-C motif chemokine ligand 2 Rattus norvegicus 81-86 9129656-8 1997 These results suggest that HIV uses both tRNA(Lys3) and tRNA(Lys5) molecules as primer, causing a switch of the PBS sequence. pbs 112-115 mitochondrially encoded tRNA glycine Homo sapiens 41-50 9129656-8 1997 These results suggest that HIV uses both tRNA(Lys3) and tRNA(Lys5) molecules as primer, causing a switch of the PBS sequence. pbs 112-115 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Mus musculus 56-65 9231243-9 1997 Plasma levels of oxytocin at 4 h intervals remained similar (P > 0.05) during the pretreatment period and throughout continuous infusion of pRLX and PBS. pbs 152-155 oxytocin/neurophysin I prepropeptide Homo sapiens 17-25 9124589-5 1997 GLP-2 increased small bowel weight in either 12% gelatin or phosphate-buffered saline (PBS) formulations (P < 0.01 vs. P < 0.05, gelatin vs. PBS, respectively), and GLP-2 was intestinotrophic following either intramuscular, intraperitoneal, or subcutaneous administration (P < 0.05 for im and ip, P < 0.001 for sc, GLP-2 vs. control). pbs 87-90 glucagon-like peptide 2 receptor Mus musculus 0-5 9124589-5 1997 GLP-2 increased small bowel weight in either 12% gelatin or phosphate-buffered saline (PBS) formulations (P < 0.01 vs. P < 0.05, gelatin vs. PBS, respectively), and GLP-2 was intestinotrophic following either intramuscular, intraperitoneal, or subcutaneous administration (P < 0.05 for im and ip, P < 0.001 for sc, GLP-2 vs. control). pbs 147-150 glucagon-like peptide 2 receptor Mus musculus 0-5 9231243-10 1997 Mean concentrations of oxytocin in PBS control heifers peaked at 0.95 pgml-1 during the corresponding infusion of 700 Uh-1 pRLX, which peaked at 0.77 pgml-1. pbs 35-38 oxytocin/neurophysin I prepropeptide Homo sapiens 23-31 7576435-9 1995 The specificity of the biosensor was demonstrated by showing that no irreversible impedance decreases occurred when the sensor was exposed to 100 ng/ml kappa-casein, or alpha-lactalbumin, in PBS. pbs 191-194 lactalbumin alpha Homo sapiens 169-186 9049044-5 1997 It was found that the production of interleukin-2 in the cells of mice treated with the antibodies was significantly lower than in the cells of PBS-treated mice. pbs 144-147 interleukin 2 Mus musculus 36-49 8978658-6 1997 In vitro release of OP-1 was also faster in PBS than in serum. pbs 44-47 bone morphogenetic protein 7 Homo sapiens 20-24 8978658-7 1997 Release kinetics of OP-1 in PBS and serum were represented by second-order polynomials. pbs 28-31 bone morphogenetic protein 7 Homo sapiens 20-24 8841663-7 1996 PBs expressed chromogranin B and secretoneurin strongly, but chromogranin A only weakly. pbs 0-3 chromogranin B Homo sapiens 14-28 8841663-7 1996 PBs expressed chromogranin B and secretoneurin strongly, but chromogranin A only weakly. pbs 0-3 secretogranin II Homo sapiens 33-46 8764006-2 1996 We have investigated the roles of NCp7 in annealing of primer tRNA(Lys3) to the PBS and in reverse transcriptase (RT) activity, using a cell-free reverse transcription reaction mixture consisting of various 5" viral RNA templates, natural primer tRNA(Lys3) or synthetic primer, human immunodeficiency virus type I (HIV-1) nucleocapsid protein (NCp7), and HIV-1 RT. pbs 80-83 mitochondrially encoded tRNA glycine Homo sapiens 62-71 8764006-9 1996 Since NCp7 appears to exert opposite effects (annealing versus dissociation) on tRNA(Lys3) and rPR substrates, the non-PBS binding regions of the tRNA(Lys3) molecule may play a role in the annealing of tRNA to the template. pbs 119-122 mitochondrially encoded tRNA glycine Homo sapiens 146-155 8551637-1 1996 The initiation of human immunodeficiency virus type 1 reverse transcription occurs by extension of a tRNA(Lys3) primer bound near the 5" end of the viral RNA genome which is designated the primer binding site (PBS). pbs 210-213 mitochondrially encoded tRNA glycine Homo sapiens 101-110 8551637-2 1996 Sequences within the viral genome upstream of the PBS which are complementary to the anticodon loop (USUU) and the T psi C loop and arm (AGGGTm psi) of tRNA(Lys3) are postulated to play a role in maintaining the selective use of tRNA(Lys3) in reverse transcription. pbs 50-53 mitochondrially encoded tRNA glycine Homo sapiens 152-161 8551637-2 1996 Sequences within the viral genome upstream of the PBS which are complementary to the anticodon loop (USUU) and the T psi C loop and arm (AGGGTm psi) of tRNA(Lys3) are postulated to play a role in maintaining the selective use of tRNA(Lys3) in reverse transcription. pbs 50-53 mitochondrially encoded tRNA glycine Homo sapiens 229-238 8551637-7 1996 A DNA sequence analysis of the PBS region from integrated proviruses revealed that by day 15 of culture, the PBS of viruses derived from pHXB2(His) and pHXB2(His-T psi C) reverted back to the wild-type PBS complementary to tRNA(Lys3). pbs 31-34 mitochondrially encoded tRNA glycine Homo sapiens 223-232 8611645-5 1996 Within 30-60 min incubation at 37 degrees C in water or in phosphate-buffered saline solution (PBS), beta 25-35 was almost fully converted to a beta-sheet structure. pbs 95-98 amyloid beta precursor protein Rattus norvegicus 142-148 9058654-4 1997 RESULTS: Compared with PBS, sera from controls and 24 patients with SLE suppressed IL-6 release from IL-1beta pretreated cells. pbs 23-26 interleukin 6 Homo sapiens 83-87 9058654-4 1997 RESULTS: Compared with PBS, sera from controls and 24 patients with SLE suppressed IL-6 release from IL-1beta pretreated cells. pbs 23-26 interleukin 1 beta Homo sapiens 101-109 9008650-6 1997 Two micrograms of TGF beta-1 in 0.1 ml phosphate-buffered saline (PBS) or 0.1 ml PBS alone was administered intraperitoneally at 8 hours after LPS injection. pbs 66-69 transforming growth factor, beta 1 Mus musculus 18-28 9051630-11 1997 Similarly, LPS-treated mice given PBS every 3 hours (n = 20) had injection-to-delivery intervals comparable to LPS-treated mice (n = 13) (median 15.5 hours, range 9.8-92 versus median 13.5 hours, range 10-105, respectively). pbs 34-37 toll-like receptor 4 Mus musculus 11-14 8948662-1 1996 We investigated the influence of different buffers (Tris-buffer and phosphate buffered saline (PBS)/Tween-20 buffer) on anti-prothrombin antibody (aPT) measurement by enzyme-linked immunosorbent assay (ELISA), employing a gamma-ray-irradiated plate. pbs 95-98 coagulation factor II, thrombin Homo sapiens 125-136 9046484-2 1996 Egg and larval production linearly increased with bovine serum albumin concentration in PBS. pbs 88-91 albumin Cavia porcellus 57-70 8974002-1 1996 As in vivo experimental system involving the local induction of interferon-alpha/beta (IFN-alpha/beta) responses was established in mice by injecting s.c. ultraviolet (UV)-inactivated herpes simplex virus (HSV) in the right ears, the left ears receiving phosphate-buffered saline (PBS) as a control. pbs 281-284 interferon alpha B Mus musculus 64-85 8949936-1 1996 The effectiveness of theta pattern primed-bursts (PBs) on development of primed-burst (PB) potentiation was investigated in hippocampal CA1 of pentylenetetrazol-kindled rats. pbs 50-53 carbonic anhydrase 1 Rattus norvegicus 136-139 8879188-3 1996 Balb-c mice were treated with phosphate-buffered saline (PBS) alone or with PBS containing 5 micrograms TNF alpha or IFN gamma through intranasal instillation. pbs 76-79 tumor necrosis factor Mus musculus 104-113 8826970-5 1996 By performing two-color immunostaining of cell surface antigens and intracellular IFN-gamma, we found that IFN-gamma positive cells in islet grafts from CFA- and PBS-injected mice were approximately equally divided between CD4+ and CD8+ T-cell subsets. pbs 162-165 interferon gamma Mus musculus 82-91 8826970-5 1996 By performing two-color immunostaining of cell surface antigens and intracellular IFN-gamma, we found that IFN-gamma positive cells in islet grafts from CFA- and PBS-injected mice were approximately equally divided between CD4+ and CD8+ T-cell subsets. pbs 162-165 interferon gamma Mus musculus 107-116 8826970-5 1996 By performing two-color immunostaining of cell surface antigens and intracellular IFN-gamma, we found that IFN-gamma positive cells in islet grafts from CFA- and PBS-injected mice were approximately equally divided between CD4+ and CD8+ T-cell subsets. pbs 162-165 CD4 antigen Mus musculus 223-226 8621554-7 1996 These findings imply that through interactions involving its p51 subunit, RT may be required to disrupt additional tRNA-viral RNA duplexes outside the pbs to proceed into productive(-)-strand DNA synthesis. pbs 151-154 tumor protein p63 Homo sapiens 61-64 8675204-4 1996 Again, flow cytometric analyses have further confirmed the significant increase in the expression of Ia antigen on dendritic cells, isolated from transgenic mice treated with IFN-gamma compared with the same from the untreated or phosphate-buffered saline (PBS)-treated transgenic mice. pbs 257-260 interferon gamma Mus musculus 175-184 8838607-2 1996 Before the hyperbaric experiment, an intracerebroventricular (ICV) injection of phosphate saline-buffered solution (PBS) or adenosine deaminase (ADA, 100 U.ml-1) in PBS was performed. pbs 165-168 adenosine deaminase Rattus norvegicus 124-143 7588564-1 1995 Human prostate-specific antigen (PSA), a 33 kDa kallikrein-like serine protease, occurring in the prostate, in seminal plasma and in blood, was prepared under nonreducing conditions in an enzymatically active form from seminal plasma by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), followed by fast copper staining, electroelution from gel slices and dialysis against isotonic phosphate-buffered saline (PBS). pbs 429-432 kallikrein related peptidase 3 Homo sapiens 6-31 7588564-1 1995 Human prostate-specific antigen (PSA), a 33 kDa kallikrein-like serine protease, occurring in the prostate, in seminal plasma and in blood, was prepared under nonreducing conditions in an enzymatically active form from seminal plasma by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), followed by fast copper staining, electroelution from gel slices and dialysis against isotonic phosphate-buffered saline (PBS). pbs 429-432 kallikrein related peptidase 3 Homo sapiens 33-36 8194630-10 1994 Animals undergoing surgery who were treated with IL-10, with or without a preoperative dose, had significantly lower postoperative adhesion scores than did control animals who postoperatively received PBS only. pbs 201-204 interleukin 10 Mus musculus 49-54 7749731-4 1995 The saline treated groups received a single 2 microliters intranigral injection of phosphate buffered saline (PBS) while the GDNF treated rats received 10 micrograms/2 microliters GDNF in PBS. pbs 188-191 glial cell derived neurotrophic factor Rattus norvegicus 180-184 7533725-1 1995 Reverse transcription of human immunodeficiency virus type 1 (HIV-1) is primed by tRNA(Lys3), which forms an 18 base pair RNA homoduplex with its 3" terminus and the primer binding site (PBS) of the viral genome. pbs 187-190 mitochondrially encoded tRNA glycine Homo sapiens 82-91 7533725-3 1995 tRNA(Lys3) was hybridized to a PBS-containing RNA template and extended by addition of deoxynucleoside triphosphates (dNTPs). pbs 31-34 mitochondrially encoded tRNA glycine Homo sapiens 0-9 7533725-7 1995 Kinetic studies comparing cleavage rates of an analogous DNA primer/PBS heteroduplex and the tRNA(Lys3)/PBS homoduplex showed that while the former is cleaved as rapidly as RT polymerizes, the latter proceeds 30-fold slower. pbs 104-107 mitochondrially encoded tRNA glycine Homo sapiens 93-102 8093036-1 1994 Cisplatin [cis-Diamminedichloroplatinum (II), DDP] generated superoxide anion (O2-), as measured by chemiluminescence from a Cypridina luciferin analog (CLA), by interaction with calf thymus DNA (ct-DNA) in phosphate-buffered saline (PBS) at pH 7.6. pbs 234-237 DD%P Bos taurus 46-49 7610763-2 1995 Most antibodies which label intracellular neurofibrillary tangles (NFTs) in AD were found to stain Pick bodies (PBs). pbs 112-115 protein interacting with PRKCA 1 Homo sapiens 99-103 7610763-5 1995 However, PBs, in contrast to NFTs, showed a paucity of staining for heparan sulfate glycosaminoglycan and basic fibroblast growth factor (bFGF). pbs 9-12 fibroblast growth factor 2 Homo sapiens 138-142 2082652-1 1990 A study of Pick bodies (PBs) was performed using immunohistochemical, ultrastructural and immunoelectron microscopic techniques. pbs 24-27 protein interacting with PRKCA 1 Homo sapiens 11-15 7514178-9 1994 Decreases in the R region on the donor template also caused a drop in initiation of transcription that was primed by tRNA(Lys-3) from the PBS. pbs 138-141 mitochondrially encoded tRNA glycine Homo sapiens 117-127 7514178-11 1994 We conclude that a transcriptional complex of tRNA(Lys-3) and RT may be associated not only with the PBS but also with other cis RNA sequences and secondary structures in a manner essential for efficient priming and template switching. pbs 101-104 mitochondrially encoded tRNA glycine Homo sapiens 46-56 7511112-12 1994 Furthermore, we found PBS-mutants to be replication-incompetent, again suggesting that HIV-1 solely uses tRNA(Lys,3) as primer. pbs 22-25 mitochondrially encoded tRNA glycine Homo sapiens 105-115 8243564-5 1993 Continuous infusion of IL-6 for 7 days resulted in elevated levels of circulating IL-6 (mean: 1872 pg/mL vs. 100 pg/mL for phosphate-buffered saline [PBS]-treated controls) and in an accelerated reconstitution of platelets starting at day 12 after irradiation. pbs 150-153 interleukin 6 Mus musculus 23-27 8128795-6 1993 Somatic cell counts (SCC) in mammary glands infused with IL-1 or IL-2 remained significantly elevated over PBS-infused control glands through day 4 after treatment. pbs 107-110 interleukin 2 Bos taurus 65-69 18613052-5 1993 During a brief harvesting phase the medium was replaced by phosphate buffered saline (PBS) containing 10 mU/mL of PI-PLC and the GPI anchored protein was cleaved from the cell surface and recovered in soluble form at up to 30% purity. pbs 86-89 phospholipase C gamma 1 Homo sapiens 114-120 8361777-2 1993 The administration of anti-IL-5 strongly depressed peripheral, cerebrospinal fluid (CSF) and medullary eosinophilic responses in mice infected with A. cantonensis, when compared with groups treated with phosphate-buffered saline solution (PBS) alone or isotype-matched rat IgG. pbs 239-242 interleukin 5 Mus musculus 27-31 8506753-3 1993 IL-2 in the serum became undetectable by 6h after a subcutaneous injection of 1 x 10(6) unit of IL-2 in phosphate-buffered saline (PBS). pbs 131-134 interleukin 2 Mus musculus 0-4 8506753-3 1993 IL-2 in the serum became undetectable by 6h after a subcutaneous injection of 1 x 10(6) unit of IL-2 in phosphate-buffered saline (PBS). pbs 131-134 interleukin 2 Mus musculus 96-100 8506753-7 1993 This activation was not observed following a single subcutaneous injection of the same amount of IL-2 in PBS. pbs 105-108 interleukin 2 Mus musculus 97-101 1723560-7 1991 GP-49 was resistant to centrifuging at 400 g for 5 min up to seven times and the treatment with 1M NaCl in PBS. pbs 107-110 leukocyte immunoglobulin-like receptor, subfamily B, member 4B Mus musculus 0-5 2021961-5 1991 The treatment of IL-2 plus cimetidine increased NK and LAK cell activities significantly and synergistically at the end of the treatment (i.e. on day 18) as well as 1 week after the treatment (i.e. on day 25), in comparison with those of the control groups (PBS, cimetidine alone, IL-2 alone). pbs 258-261 interleukin 2 Mus musculus 17-21 2021961-8 1991 A significant increase in asialo GM1-positive cells and IL-2-receptor-positive cells was detected in the group treated with IL-2 plus cimetidine in comparison with the PBS and IL-2 control groups. pbs 168-171 interleukin 2 Mus musculus 124-128 2021961-8 1991 A significant increase in asialo GM1-positive cells and IL-2-receptor-positive cells was detected in the group treated with IL-2 plus cimetidine in comparison with the PBS and IL-2 control groups. pbs 168-171 interleukin 2 Mus musculus 124-128 8151729-5 1994 In animals where LIF was administered neuronal loss was significantly reduced: 2 days after LIF treatment neuronal loss was 19.5% compared to 43% in PBS-treated animals; 3 days after LIF treatment neuronal loss was 20.4% compared to 40.2% in PBS-treated animals; however, 7 days after LIF treatment there was no significant reduction in the number of neurons lost. pbs 149-152 LIF, interleukin 6 family cytokine Rattus norvegicus 17-20 8151729-5 1994 In animals where LIF was administered neuronal loss was significantly reduced: 2 days after LIF treatment neuronal loss was 19.5% compared to 43% in PBS-treated animals; 3 days after LIF treatment neuronal loss was 20.4% compared to 40.2% in PBS-treated animals; however, 7 days after LIF treatment there was no significant reduction in the number of neurons lost. pbs 242-245 LIF, interleukin 6 family cytokine Rattus norvegicus 17-20 8109618-5 1994 Then EGF in phosphate buffered saline (PBS) was applied to the Gelfoam pledget (50 microL of 0.5 mg EGF/mL PBS). pbs 39-42 epidermal growth factor Homo sapiens 5-8 8331927-8 1993 Mean serum IL-6 levels 3 hr after intraperitoneal IL-1 alpha (10 micrograms/kg) were: PBS, 3730 +/- 526 (mean +/- SEM pg/ml); IL-1ra (LD), 1156 +/- 398; and IL-1ra (HD), 594 +/- 30 (P < 0.01, IL-1ra HD or LD vs PBS). pbs 86-89 interleukin 6 Mus musculus 11-15 8383213-5 1993 Another region from PBS to the 5"-terminal 60 residues of the gag gene, partially overlapping the dimer region, likely provides essential elements for the MA(p15) binding reaction, although the presence of either the 3" or 5" neighboring sequences increases the complex-forming efficiency significantly, and each of the substructures predicted within the core region has, if any, only very weak affinity to MA(p15). pbs 20-23 cyclin dependent kinase inhibitor 2B Homo sapiens 158-161 8449215-5 1993 In the absence of GSH there was an overall 20-fold reduction of the number of IFN-gamma pc in splenocyte cultures of normal or PBS-injected rats, which was further reduced to a 60- to 70-fold-lower level in cultures of rats exposed to HgCl2. pbs 127-130 interferon gamma Rattus norvegicus 78-87 8095432-1 1993 We have studied the induction of c-fos immunoreactivity (c-fos IR) in catecholaminergic and vasopressinergic immunoreactive neurons after repeated phosphate-buffered saline (PBS) loading or after repeated elicitation of the baroreceptor reflex via repeated infusion of the vasoconstrictor agent L-phenylephrine. pbs 174-177 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 33-38 8095432-1 1993 We have studied the induction of c-fos immunoreactivity (c-fos IR) in catecholaminergic and vasopressinergic immunoreactive neurons after repeated phosphate-buffered saline (PBS) loading or after repeated elicitation of the baroreceptor reflex via repeated infusion of the vasoconstrictor agent L-phenylephrine. pbs 174-177 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 57-62 8094341-1 1993 Long-term potentiation (LTP) of the basal dendritic population excitatory postsynaptic potential (EPSP) in hippocampal CA1 was readily elicited in behaving rats, without afterdischarges (ADs), by theta-frequency-patterned primed bursts (PBs) delivered to the contralateral CA1. pbs 237-240 carbonic anhydrase 1 Rattus norvegicus 119-122 1369829-2 1992 To elucidate the mechanisms involved with IL-1 alpha-induced promotion of alloengraftment and hematopoietic recovery, we performed sequential splenic FACS studies on transplanted mice and secondary transfer studies in syngeneic mice given IL-1 alpha or PBS. pbs 253-256 interleukin 1 alpha Mus musculus 42-52 1424718-4 1992 Significantly larger endothelial wounds were present six days after wounding when the eyes were treated with 10 micrograms of bFGF/eye compared with controls treated with PBS only. pbs 171-174 fibroblast growth factor 2 Homo sapiens 126-130 1714513-5 1991 An additional mutation in the PBS was created in which the second nine nucleotides were deleted and nine additional nucleotides were substituted [Lys(1-9)]. pbs 30-33 CD8b molecule Homo sapiens 146-153 1714513-9 1991 The transfection of plasmids containing HIV-1 proviral genomes with the delta PBS and PBS (delta 1-9) mutations did not produce infectious virus. pbs 86-89 delta like canonical Notch ligand 4 Homo sapiens 91-100 1714513-10 1991 In contrast, the HIV-1 proviral genomes with the delta 10-18, delta 7-18, and Lys(1-9) mutations in the PBS produced infectious virus upon transfection, although the kinetics of appearance was significantly delayed for the mutant viruses compared with the wild type. pbs 104-107 lymphocyte antigen 9 Homo sapiens 78-85 1781077-6 1991 Dissolution of argon gas in the PBS before exposure enhanced the SSB effect and the H2O2 production. pbs 32-35 lupus La protein Cricetulus griseus 65-68 1781077-7 1991 Addition of catalase to the cavitated PBS before cell treatment eliminated the H2O2 and the SSB gamma effect. pbs 38-41 lupus La protein Cricetulus griseus 92-95 2339923-12 1990 Neurotensin stimulates pancreaticobiliary secretions (PBS), which are known to stimulate gut growth. pbs 54-57 neurotensin Rattus norvegicus 0-11 33822096-9 2021 Phosphate buffer saline (PBS) injection also upregulated the expression levels of abaecin, defensin, and domeless in A. mellifera and A. cerana larvae. pbs 25-28 abaecin Apis mellifera 82-89 34939294-5 2021 A range of novel targeted therapies now exist and are Pharmaceutical Benefits Scheme (PBS)-subsidised for targets such as EGFR, ALK and ROS1, with many others, such as KRAS G12C, NTRK, MET, RET and HER2, also with therapies rapidly being developed. pbs 86-89 epidermal growth factor receptor Homo sapiens 122-126 34942204-4 2022 The GMP size in PDI-abd-6 was not significantly different from that in WT, whereas the accumulation of protein bodies (PBs) increased during grain development. pbs 119-122 prolyl 4-hydroxylase subunit beta Homo sapiens 16-19 24763891-10 2014 Compared to PBS-treated psoriatic animals, treatment with anti-FGF10, like hydrocortisone butyrate, greatly inhibited the severity of psoriasis-like lesions by reducing the Baker"s scores, the thickness of epidermis, and the numbers of monocyte infiltrates in the dermis of animals. pbs 12-15 fibroblast growth factor 10 Homo sapiens 63-68 34665905-12 2022 On Days 3, 7, and 14 after wounding, immunohistochemical staining showed the infiltration of neutrophils and macrophages, and the expression of inflammation-related proteins (IL-1beta, TNF-alpha, and NLRP3) were upregulated in gouty ulcers compared with those of PBS controls. pbs 263-266 NLR family, pyrin domain containing 3 Rattus norvegicus 200-205 34939294-5 2021 A range of novel targeted therapies now exist and are Pharmaceutical Benefits Scheme (PBS)-subsidised for targets such as EGFR, ALK and ROS1, with many others, such as KRAS G12C, NTRK, MET, RET and HER2, also with therapies rapidly being developed. pbs 86-89 ALK receptor tyrosine kinase Homo sapiens 128-131 34939294-5 2021 A range of novel targeted therapies now exist and are Pharmaceutical Benefits Scheme (PBS)-subsidised for targets such as EGFR, ALK and ROS1, with many others, such as KRAS G12C, NTRK, MET, RET and HER2, also with therapies rapidly being developed. pbs 86-89 ROS proto-oncogene 1, receptor tyrosine kinase Homo sapiens 136-140 34834039-6 2021 After immobilizing specific antibodies in the channel, the FET can detect the SARS-CoV-2 spike protein in 15 min at a concentration of 1 pg/mL in phosphate-buffered saline (PBS) and 1 ng/mL in human serum. pbs 173-176 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 89-94 34916764-5 2021 Results: The PBS values for SAP (p < .05) were higher than those for CP and were not influenced by the root third and resin cement (p > .05). pbs 13-16 amyloid P component, serum Bos taurus 28-31 34517645-6 2021 Under the optimal conditions of 30 mM K3(Fe(CN)6), OD600 = 1 cell concentration, and 50 mM phosphate-buffered solution (PBS), the half-maximal inhibitory concentration (IC50) values measured for Cd2+, Cu2+ and Ni2+ were 3.99 mg/L, 1.16 mg/L and 2.37 mg/L, respectively. pbs 120-123 CD2 molecule Homo sapiens 195-198 34839596-26 2022 On PID 1, the wound sizes of nude mice were almost the same in PBS alone group, ADM alone group, ESC alone group, and ESC/ADM group. pbs 63-66 phosphotyrosine interaction domain containing 1 Mus musculus 3-8 34660997-9 2021 PBS washing for 10 consecutive cycles at 50 mV/s did not improve the electrode performance, except for CNF/ta-C, which performed better after PBS washing. pbs 142-145 NPHS1 adhesion molecule, nephrin Homo sapiens 103-106 34086965-8 2021 Transmission electron microscopy indicated that gfs9-5 hyperaccumulated structures corresponding to autophagosomes and PBs. pbs 119-122 CLEC16A-like protein Arabidopsis thaliana 48-52 34086965-12 2021 In gfs9-5, the YFP-ATG8e proteins and PBs could be delivered to the vacuole and autophagic flux was increased. pbs 38-41 CLEC16A-like protein Arabidopsis thaliana 3-7 34823320-9 2021 (2) The mRNA and protein expression levels of MMP-2, Slug and CXCR4 in HTR-8/SVneo cells of TNF-alpha group were significantly lower than those in PBS control group (P<0.05) and those in TNF-alpha along with ETA group (P<0.05). pbs 147-150 matrix metallopeptidase 2 Homo sapiens 46-51 34823320-9 2021 (2) The mRNA and protein expression levels of MMP-2, Slug and CXCR4 in HTR-8/SVneo cells of TNF-alpha group were significantly lower than those in PBS control group (P<0.05) and those in TNF-alpha along with ETA group (P<0.05). pbs 147-150 snail family transcriptional repressor 2 Homo sapiens 53-57 34823320-9 2021 (2) The mRNA and protein expression levels of MMP-2, Slug and CXCR4 in HTR-8/SVneo cells of TNF-alpha group were significantly lower than those in PBS control group (P<0.05) and those in TNF-alpha along with ETA group (P<0.05). pbs 147-150 C-X-C motif chemokine receptor 4 Homo sapiens 62-67 34821625-7 2021 The PBS-Cu-Ni working electrodes enabled detection of glucose with a limit of detection (LOD) of 4.2 nM, a dynamic response from 5 nM to 20 mM, and sensitivity of 5.47 +- 0.45 muA cm-2/log10(mole.L-1) at an applied potential of 0.2 V. In addition to the ultralow LOD, the sensors are selective toward glucose in the presence of physiologically relevant concentrations of ascorbic acid and uric acid spiked in artificial saliva. pbs 4-7 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Homo sapiens 101-103 34821625-7 2021 The PBS-Cu-Ni working electrodes enabled detection of glucose with a limit of detection (LOD) of 4.2 nM, a dynamic response from 5 nM to 20 mM, and sensitivity of 5.47 +- 0.45 muA cm-2/log10(mole.L-1) at an applied potential of 0.2 V. In addition to the ultralow LOD, the sensors are selective toward glucose in the presence of physiologically relevant concentrations of ascorbic acid and uric acid spiked in artificial saliva. pbs 4-7 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Homo sapiens 131-133 34720748-9 2021 The O2 + PBS mice exhibited significantly higher kidney injury scores, 8-hydroxy-2"-deoxyguanosine (8-OHdG) and nuclear factor-kappaB (NF-kappaB) expression, and cytokine levels than did the RA + PBS mice or RA + anti-Tn mice. pbs 9-12 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 112-133 34720748-9 2021 The O2 + PBS mice exhibited significantly higher kidney injury scores, 8-hydroxy-2"-deoxyguanosine (8-OHdG) and nuclear factor-kappaB (NF-kappaB) expression, and cytokine levels than did the RA + PBS mice or RA + anti-Tn mice. pbs 9-12 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 135-144 34696934-5 2021 PBs composed of the alpha-helical domain of pneumococcal surface protein A (PspAalpha) provided superior protection against colonization with S. pneumoniae compared to soluble PspAalpha. pbs 0-3 pneumococcal surface protein A Streptococcus pneumoniae 44-74 34702739-5 2021 Multiagent molecular MRI performed to assess oxidative stress (targeting myeloperoxidase (MPO) using MPO-bis-5-hydroxytryptamide diethylenetriaminepentaacetate gadolinium (Gd)) and phagocytosis (using cross-linked iron oxide (CLIO) nanoparticles) in vivo revealed that d-mannose-treated mice had smaller total MPO-Gd+ areas than those of PBS-control mice, consistent with decreased MPO-mediated oxidative stress. pbs 338-341 myeloperoxidase Mus musculus 73-88 34702739-5 2021 Multiagent molecular MRI performed to assess oxidative stress (targeting myeloperoxidase (MPO) using MPO-bis-5-hydroxytryptamide diethylenetriaminepentaacetate gadolinium (Gd)) and phagocytosis (using cross-linked iron oxide (CLIO) nanoparticles) in vivo revealed that d-mannose-treated mice had smaller total MPO-Gd+ areas than those of PBS-control mice, consistent with decreased MPO-mediated oxidative stress. pbs 338-341 myeloperoxidase Mus musculus 382-385 34454177-7 2021 Furthermore, compared with non-irradiated mice, mice in the 25 Gy + PBS group showed a high senescence-associated-beta-galactosidase-positive cell number and upregulated senescence-related gene (p16INK4a, p19Arf, p21) and senescence-associated secretory phenotypic factor (MMP3, IL-6, PAI-1, NF-kappaB, and TGF-beta) expression, all of which were downregulated in the hDPSC-sEV group. pbs 68-71 cyclin dependent kinase inhibitor 2A Mus musculus 195-203 34454177-7 2021 Furthermore, compared with non-irradiated mice, mice in the 25 Gy + PBS group showed a high senescence-associated-beta-galactosidase-positive cell number and upregulated senescence-related gene (p16INK4a, p19Arf, p21) and senescence-associated secretory phenotypic factor (MMP3, IL-6, PAI-1, NF-kappaB, and TGF-beta) expression, all of which were downregulated in the hDPSC-sEV group. pbs 68-71 cyclin dependent kinase inhibitor 2A Mus musculus 205-211 34454177-7 2021 Furthermore, compared with non-irradiated mice, mice in the 25 Gy + PBS group showed a high senescence-associated-beta-galactosidase-positive cell number and upregulated senescence-related gene (p16INK4a, p19Arf, p21) and senescence-associated secretory phenotypic factor (MMP3, IL-6, PAI-1, NF-kappaB, and TGF-beta) expression, all of which were downregulated in the hDPSC-sEV group. pbs 68-71 cyclin-dependent kinase inhibitor 1A (P21) Mus musculus 213-216 34454177-7 2021 Furthermore, compared with non-irradiated mice, mice in the 25 Gy + PBS group showed a high senescence-associated-beta-galactosidase-positive cell number and upregulated senescence-related gene (p16INK4a, p19Arf, p21) and senescence-associated secretory phenotypic factor (MMP3, IL-6, PAI-1, NF-kappaB, and TGF-beta) expression, all of which were downregulated in the hDPSC-sEV group. pbs 68-71 matrix metallopeptidase 3 Mus musculus 273-277 34454177-7 2021 Furthermore, compared with non-irradiated mice, mice in the 25 Gy + PBS group showed a high senescence-associated-beta-galactosidase-positive cell number and upregulated senescence-related gene (p16INK4a, p19Arf, p21) and senescence-associated secretory phenotypic factor (MMP3, IL-6, PAI-1, NF-kappaB, and TGF-beta) expression, all of which were downregulated in the hDPSC-sEV group. pbs 68-71 interleukin 6 Mus musculus 279-283 34454177-7 2021 Furthermore, compared with non-irradiated mice, mice in the 25 Gy + PBS group showed a high senescence-associated-beta-galactosidase-positive cell number and upregulated senescence-related gene (p16INK4a, p19Arf, p21) and senescence-associated secretory phenotypic factor (MMP3, IL-6, PAI-1, NF-kappaB, and TGF-beta) expression, all of which were downregulated in the hDPSC-sEV group. pbs 68-71 serine (or cysteine) peptidase inhibitor, clade E, member 1 Mus musculus 285-290 34454177-7 2021 Furthermore, compared with non-irradiated mice, mice in the 25 Gy + PBS group showed a high senescence-associated-beta-galactosidase-positive cell number and upregulated senescence-related gene (p16INK4a, p19Arf, p21) and senescence-associated secretory phenotypic factor (MMP3, IL-6, PAI-1, NF-kappaB, and TGF-beta) expression, all of which were downregulated in the hDPSC-sEV group. pbs 68-71 transforming growth factor alpha Mus musculus 307-315 34412756-23 2021 Compared with PBS control group, co-culture with neutrophils could inhibit the secretion of IL-2 by T lymphocytes (ng/L: 1 938.00+-68.45 vs. 2 547.00+-218.00, P < 0.05), and the inhibitory effect of neutrophils stimulated by LPS was more obvious (ng/L: 1 073.00+-34.39 vs. 2 547.00+-218.00, P < 0.05). pbs 14-17 interleukin 2 Mus musculus 92-96 34575510-8 2021 In the LCP-EGFR siRNA+LCP Pyro PA without light group and LCP EGFR siRNA + PBS with light group, SCC4 and SAS tumor volumes were reduced by ~140% and ~150%, respectively, compared to the PBS group. pbs 75-78 colon tumor susceptibility 4 Mus musculus 97-101 34575510-8 2021 In the LCP-EGFR siRNA+LCP Pyro PA without light group and LCP EGFR siRNA + PBS with light group, SCC4 and SAS tumor volumes were reduced by ~140% and ~150%, respectively, compared to the PBS group. pbs 187-190 colon tumor susceptibility 4 Mus musculus 97-101 34575510-9 2021 The LCP EGFR siRNA+PDT group of SCC4 and SAS tumor volumes were reduced by ~205% and ~220%, respectively, compared to the PBS group. pbs 122-125 colon tumor susceptibility 4 Mus musculus 32-36 34543130-5 2021 BMP-2 significantly increased in MSCs recipients 3 weeks postfracture and increased in all groups 8 weeks postfracture with significant increases in MSC recipients than the fixation and PBS groups. pbs 186-189 bone morphogenetic protein 2 Mus musculus 0-5 34311580-4 2021 In this study, we discovered that XRN1 and nonstructural protein 1 (NS1) of IAV are directly associated and colocalize in the PBs. pbs 126-129 5'-3' exoribonuclease 1 Homo sapiens 34-38 34311580-4 2021 In this study, we discovered that XRN1 and nonstructural protein 1 (NS1) of IAV are directly associated and colocalize in the PBs. pbs 126-129 influenza virus NS1A binding protein Homo sapiens 68-71 34463232-10 2022 Serum E2, LH, SOD, CAT levels were significantly decreased, FSH levels were remarkably increased in D-gal group than PBS group (p<0.05). pbs 117-120 catalase Mus musculus 19-22 34463232-10 2022 Serum E2, LH, SOD, CAT levels were significantly decreased, FSH levels were remarkably increased in D-gal group than PBS group (p<0.05). pbs 117-120 follicle stimulating hormone beta Mus musculus 60-63 34253659-1 2021 OBJECTIVES: In Australia, therapeutic interchange of angiotensin-converting enzyme (ACE) inhibitors could generate savings for patients and the Pharmaceutical Benefits Scheme (PBS). pbs 176-179 angiotensin I converting enzyme Homo sapiens 53-82 34253659-1 2021 OBJECTIVES: In Australia, therapeutic interchange of angiotensin-converting enzyme (ACE) inhibitors could generate savings for patients and the Pharmaceutical Benefits Scheme (PBS). pbs 176-179 angiotensin I converting enzyme Homo sapiens 84-87 34383816-11 2021 The prices of insulin products were much lower than PBS prices of Australian in this study, with the MPRs less than 1 (0.32 to 0.71 in 2016 vs. 0.30 to 0.68 in 2018) for all insulin types. pbs 52-55 insulin Homo sapiens 174-181 34182569-4 2021 Circulating IgG- and IgA-secreting PBs targeting the S protein peaked one week after the second immunization then declined, becoming undetectable three weeks later. pbs 35-38 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 53-54 34149899-6 2021 Compared with the PBS control group, the A549, A549/DDP and A549/Taxol cells treated with NaI131, GA or a combination of the drugs exhibited G2/M arrest and increased percentages of total apoptotic cells, as well as significantly decreased protein levels of CDK1, cyclin B, mtp53, HSP90, Bcl-2 and P-gp, increased protein levels of Bax and decreased mRNA levels of p53 and HSP90. pbs 18-21 cyclin dependent kinase 1 Homo sapiens 258-262 34149899-6 2021 Compared with the PBS control group, the A549, A549/DDP and A549/Taxol cells treated with NaI131, GA or a combination of the drugs exhibited G2/M arrest and increased percentages of total apoptotic cells, as well as significantly decreased protein levels of CDK1, cyclin B, mtp53, HSP90, Bcl-2 and P-gp, increased protein levels of Bax and decreased mRNA levels of p53 and HSP90. pbs 18-21 BCL2 apoptosis regulator Homo sapiens 288-293 34149899-6 2021 Compared with the PBS control group, the A549, A549/DDP and A549/Taxol cells treated with NaI131, GA or a combination of the drugs exhibited G2/M arrest and increased percentages of total apoptotic cells, as well as significantly decreased protein levels of CDK1, cyclin B, mtp53, HSP90, Bcl-2 and P-gp, increased protein levels of Bax and decreased mRNA levels of p53 and HSP90. pbs 18-21 ATP binding cassette subfamily B member 1 Homo sapiens 298-302 34149899-6 2021 Compared with the PBS control group, the A549, A549/DDP and A549/Taxol cells treated with NaI131, GA or a combination of the drugs exhibited G2/M arrest and increased percentages of total apoptotic cells, as well as significantly decreased protein levels of CDK1, cyclin B, mtp53, HSP90, Bcl-2 and P-gp, increased protein levels of Bax and decreased mRNA levels of p53 and HSP90. pbs 18-21 BCL2 associated X, apoptosis regulator Homo sapiens 332-335 34149899-6 2021 Compared with the PBS control group, the A549, A549/DDP and A549/Taxol cells treated with NaI131, GA or a combination of the drugs exhibited G2/M arrest and increased percentages of total apoptotic cells, as well as significantly decreased protein levels of CDK1, cyclin B, mtp53, HSP90, Bcl-2 and P-gp, increased protein levels of Bax and decreased mRNA levels of p53 and HSP90. pbs 18-21 tumor protein p53 Homo sapiens 365-368 34149899-6 2021 Compared with the PBS control group, the A549, A549/DDP and A549/Taxol cells treated with NaI131, GA or a combination of the drugs exhibited G2/M arrest and increased percentages of total apoptotic cells, as well as significantly decreased protein levels of CDK1, cyclin B, mtp53, HSP90, Bcl-2 and P-gp, increased protein levels of Bax and decreased mRNA levels of p53 and HSP90. pbs 18-21 heat shock protein 90 alpha family class A member 1 Homo sapiens 373-378 34071825-4 2021 Our data show that IL-16 expression is significantly increased in the brain and spinal cord tissues of EAE mice compared to phosphate buffered saline (PBS) immunised controls. pbs 151-154 interleukin 16 Mus musculus 19-24 34181385-5 2021 The sensor is created by functionalizing the WSe2 monolayers with a monoclonal antibody against the SARS-CoV-2 spike protein and exhibits a detection limit of down to 25 fg/muL in 0.01X phosphate-buffered saline (PBS). pbs 213-216 tripartite motif containing 37 Homo sapiens 173-176 34672292-8 2021 Abeta3-10-KLH and Abeta1-42 inoculations reduced Abeta load and suppressed astrocytes and microglia proliferation in the cortex compared with the PBS group. pbs 146-149 amyloid beta (A4) precursor protein Mus musculus 49-54 34672292-9 2021 While there was no significant difference between the two groups, Abeta3-10-KLH and Abeta1-42 vaccines decreased the brain levels of IL-1beta and TNF-alpha as compared with the PBS group, but without difference between the two vaccines. pbs 177-180 interleukin 1 alpha Mus musculus 133-141 34672292-9 2021 While there was no significant difference between the two groups, Abeta3-10-KLH and Abeta1-42 vaccines decreased the brain levels of IL-1beta and TNF-alpha as compared with the PBS group, but without difference between the two vaccines. pbs 177-180 tumor necrosis factor Mus musculus 146-155 35482593-8 2022 Under optimum conditions, the linear detection range of the immunosensor for CD44 antigen is 5.0 fg mL-1 to 50.0 mug mL-1 and the limit of detection is 2.0 and 1.90 fg mL-1 as observed via DPV and EIS, respectively, in PBS. pbs 219-222 L1 cell adhesion molecule Mus musculus 100-104 35617799-9 2022 We demonstrated the detection of recombinant GFAP protein in phosphate-buffered saline (PBS) and in mouse blood samples (detection limit 0.01 ng/mL) and of physiological GFAP in blood and plasma samples (detection limit 1.0 ng/mL) obtained from acute stroke patients. pbs 88-91 glial fibrillary acidic protein Mus musculus 45-49 35482593-8 2022 Under optimum conditions, the linear detection range of the immunosensor for CD44 antigen is 5.0 fg mL-1 to 50.0 mug mL-1 and the limit of detection is 2.0 and 1.90 fg mL-1 as observed via DPV and EIS, respectively, in PBS. pbs 219-222 L1 cell adhesion molecule Mus musculus 168-172 35604834-4 2022 In the model group, spleen-derived CD4 + T cells of normal rats were treated with 5-azacytidine (5-Aza), complete Freund"s adjuvant and Phosphate Buffered Saline (PBS), then transferred into naive immunocompetent rats. pbs 163-166 Cd4 molecule Rattus norvegicus 35-38 35306709-4 2022 Consequently, Ni2 P-Ni12 P5 @Ni3 S2 /NF required only 32, 46 and 34 mV overpotentials to drive 10 mA cm-2 in 1.0 M KOH, 0.5 M H2 SO4 and 1.0 M phosphate-buffered saline (PBS) electrolytes, respectively, exceeding almost all the previously reported non-noble metal-based electrocatalysts. pbs 170-173 neurofascin Homo sapiens 37-39 35403650-5 2022 In a standard phosphate buffered saline (PBS) environment, PDA@Ag could reach a low detection limit of 0.01 ng mL-1 cardiac troponin I (cTn I) with a good linear relationship. pbs 41-44 troponin I3, cardiac type Homo sapiens 136-141 35108420-6 2022 As a result, fundus examination suggests that after intravitreous injection of anti-FBN2 protein, there were a large patchy yellow white degeneration region and numerous pigmentations in the retina in anti-FBN2-treated mice; by contrast, there was no apparent change in mice from the NC and PBS groups. pbs 291-294 fibrillin 2 Mus musculus 84-88 35108420-6 2022 As a result, fundus examination suggests that after intravitreous injection of anti-FBN2 protein, there were a large patchy yellow white degeneration region and numerous pigmentations in the retina in anti-FBN2-treated mice; by contrast, there was no apparent change in mice from the NC and PBS groups. pbs 291-294 fibrillin 2 Mus musculus 206-210 35496265-12 2022 Differences in concentrations of interleukin-6 in the amniotic fluid were found among the subgroups of the gestational sacs (with lipopolysaccharide: median 762 pg/ml; without lipopolysaccharide: median 35.6 pg/ml; with PBS: median 35.6 pg/ml; and without PBS: median 35.6 pg/ml; p < 0.0001). pbs 220-223 interleukin 6 Rattus norvegicus 33-46 35394760-3 2022 When operated in a 0.1 M phosphate-buffered saline (PBS) solution with 0.1 M NaNO3, FeOOH/CP is able to obtain a large NH3 yield of 2419 mug h-1 cm-2 and a surprisingly high Faradic efficiency of 92% with excellent stability. pbs 52-55 ceruloplasmin Homo sapiens 90-92 35443010-4 2022 On days 0 and 14, the mice were administered PBS or sensitized to OVA in PBS. pbs 73-76 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 66-69 35108359-6 2022 Our results highlight a cell-autonomous function that links kinase activity to the PBs" newly acquired secretion ability and the adaptability observed in both normal and malignant PCs, and finally should prompt the reconsideration of PIM2 as a therapeutic target in multiple myeloma. pbs 83-86 Pim-2 proto-oncogene, serine/threonine kinase Homo sapiens 234-238 35297932-11 2022 The microfluidic immunosensing device exhibited a linear detection range of 10-1000 pg mL-1 for the detection of GFAP within 30 min, with a limit of detection (LoD) and sensitivity of 3 pg mL-1 and 39 mL pg-1 mm-2 in PBS, respectively. pbs 217-220 L1 cell adhesion molecule Mus musculus 87-91 35081773-1 2022 Attenuated total reflection-far-ultraviolet (ATR-FUV) spectra in the 145 - 250 nm region were studied for four kinds of proteins (two alpha-helix rich proteins; bovine serum albumin (BSA) and lysozyme, and two beta-sheet rich proteins; concanavalin A and gamma-globulin) in different solutions (pure water and phosphate buffered saline (PBS)) with different concentrations. pbs 337-340 ATR serine/threonine kinase Homo sapiens 45-48 35425642-9 2022 Results: Peritumoral brain edema grade, AP grade, PTFV, and MIB-LI grade were statistically associated with PBS. pbs 108-111 MIB E3 ubiquitin protein ligase 1 Homo sapiens 60-63 35443857-8 2022 The expression of Sirt6 was lower in RAW264.7 cells of the lipopolysaccharides (LPS) + interferon-gamma (IFN-gamma) group compared with the phosphate buffer saline (PBS) group, but higher than in the IL-4 group. pbs 165-168 sirtuin 6 Mus musculus 18-23 34996003-3 2022 Herein, an ascorbic acid (AA)-mediated organic photoelectrochemical transistor (OPECT) sensing strategy was reported for the detection of H-FABP in phosphate buffer saline (PBS) solution and human serum. pbs 173-176 fatty acid binding protein 3 Homo sapiens 138-144 35178861-11 2022 Evaluation of components of the NLRP3 inflammasome revealed an increased percentage of apoptosis-associated speck-like protein containing a CARD domain (ASC)-expressing, caspase-1-expressing, and interleukin-1beta-expressing cells in the myocardium and in the spleen of CVB3 + PBS vs. control mice, which was reduced in CVB3 + colchicine compared with CVB3 + PBS mice. pbs 277-280 NLR family pyrin domain containing 3 Homo sapiens 32-37 35178861-11 2022 Evaluation of components of the NLRP3 inflammasome revealed an increased percentage of apoptosis-associated speck-like protein containing a CARD domain (ASC)-expressing, caspase-1-expressing, and interleukin-1beta-expressing cells in the myocardium and in the spleen of CVB3 + PBS vs. control mice, which was reduced in CVB3 + colchicine compared with CVB3 + PBS mice. pbs 277-280 PYD and CARD domain containing Homo sapiens 153-156 35178861-11 2022 Evaluation of components of the NLRP3 inflammasome revealed an increased percentage of apoptosis-associated speck-like protein containing a CARD domain (ASC)-expressing, caspase-1-expressing, and interleukin-1beta-expressing cells in the myocardium and in the spleen of CVB3 + PBS vs. control mice, which was reduced in CVB3 + colchicine compared with CVB3 + PBS mice. pbs 359-362 NLR family pyrin domain containing 3 Homo sapiens 32-37 35178861-11 2022 Evaluation of components of the NLRP3 inflammasome revealed an increased percentage of apoptosis-associated speck-like protein containing a CARD domain (ASC)-expressing, caspase-1-expressing, and interleukin-1beta-expressing cells in the myocardium and in the spleen of CVB3 + PBS vs. control mice, which was reduced in CVB3 + colchicine compared with CVB3 + PBS mice. pbs 359-362 PYD and CARD domain containing Homo sapiens 153-156 35178861-13 2022 A 1.9-fold (P < 0.05) and 4.6-fold (P < 0.001) reduced cardiac gene expression of the fibrotic markers, Col1a1 and lysyl oxidase, respectively, was detected in CVB3 + colchicine mice compared with CVB3 + PBS animals, and reflected by a 2.2-fold (P < 0.05) decreased Collagen I/III protein ratio. pbs 204-207 collagen type I alpha 1 chain Homo sapiens 104-110 35347312-7 2022 We show that these interactions disrupt genome packaging, and additionally show that the PBS-SL1 interaction unexpectedly couples the PBS with dimerization and Pr55Gag binding. pbs 89-92 Pr55(Gag) Human immunodeficiency virus 1 160-167 35347312-7 2022 We show that these interactions disrupt genome packaging, and additionally show that the PBS-SL1 interaction unexpectedly couples the PBS with dimerization and Pr55Gag binding. pbs 134-137 Pr55(Gag) Human immunodeficiency virus 1 160-167 35406194-7 2022 The electrochemically regulated bioanode (MWCNT/ZnS/AgNWs/PANI/Frt/GOx) obtained an open-circuit voltage of 0.55 V and produced a maximal current density of 7.6 mA cm-2 at a glucose concentration of 50 mM prepared in phosphate buffer solution (PBS) (pH 7.0) as a supporting electrolyte at a scan rate of 100 mV s-1. pbs 244-247 hydroxyacid oxidase 1 Homo sapiens 67-70 34978758-6 2022 This insight was further revealed by the visualization of the pH gradient near the electrode surface during NARR and confirmed by the DFT calculations, that PBS notably facilitated the proton transport and active mitigation over the proton transfer barrier. pbs 157-160 ras-related protein Rab-34 Homo sapiens 108-112 35325966-22 2022 After stimulation of 12 h, the protein expression of iNOS of RAW264.7 cells in LPS alone group was significantly higher than that in PBS group and LPS+ADSCs-Exos group, respectively (with t values of 11.20 and 5.06, respectively, P<0.05 or P<0.01), and the protein expression of Arg1 was significantly lower than that in LPS+ADSCs-Exos group (t=15.01, P<0.01). pbs 133-136 nitric oxide synthase 2, inducible Mus musculus 53-57 35325966-23 2022 On PID 1, the serum concentrations of IL-1beta and TNF-alpha and the mRNA expressions of IL-1beta, TNF-alpha, and IL-6 in wound tissue of mice in ADSCs-Exos group were significantly those in lower than PBS group (with t values of 15.44, 12.24, 9.24, 7.12, and 10.62, respectively, P<0.01). pbs 202-205 interleukin 1 alpha Mus musculus 89-97 35257841-15 2022 The BMD of the proximal femur and lumbar spine and the PBS of the proximal femur were significantly higher in the OPLL group than in the non-OPLL group. pbs 55-58 OPLL Homo sapiens 114-118 35257841-17 2022 However, the BMD and PBS of the proximal femur and lumbar spine were significantly higher in the OPLL females than in the non-OPLL females. pbs 21-24 OPLL Homo sapiens 97-101 35496265-12 2022 Differences in concentrations of interleukin-6 in the amniotic fluid were found among the subgroups of the gestational sacs (with lipopolysaccharide: median 762 pg/ml; without lipopolysaccharide: median 35.6 pg/ml; with PBS: median 35.6 pg/ml; and without PBS: median 35.6 pg/ml; p < 0.0001). pbs 256-259 interleukin 6 Rattus norvegicus 33-46 35069853-8 2022 The expression levels of Src mRNA in the control, PBS, empty vector and siRNA groups were 110+-30.7x103, 253+-55.4x103, 254+-41.3x103 and 180+-50.9x103, respectively. pbs 50-53 SRC proto-oncogene, non-receptor tyrosine kinase Rattus norvegicus 25-28 2453331-8 1988 These observations suggest that SPKs and PBs in CA1 represent population EPSPs and multiple population spikes, respectively and that these CA1 events are triggered by brief, high frequency burst discharges of CA3 pyramidal cells via the Schaffer collateral and commissural pathway. pbs 41-44 carbonic anhydrase 1 Rattus norvegicus 48-51 34949712-5 2022 Down-regulation of RHA or the anomalous shape of the PBS segment abrogated hypermethylated caps and derepressed eIF4E binding for virion protein translation during global down-regulation of host translation. pbs 53-56 eukaryotic translation initiation factor 4E Homo sapiens 112-117 35200804-4 2022 Results show that a compact PBS with a coupling length of 6.45 microm is achieved, together with the extinction ratio (ER) of 27.54/31.88 dB, the insertion loss of 0.12/0.14 dB, and the reflection loss of -43.67/-30.50dB, respectively, for TE/TM mode at the wavelength of 1.55 microm. pbs 28-31 epiregulin Homo sapiens 119-121 35371413-6 2022 As proof-of-principle studies, we demonstrate the detection of SARS-CoV-2 spike protein in both phosphate-buffered saline (PBS) buffer and universal transport medium (UTM) (limit of detection (LoD): 100 fg/mL). pbs 123-126 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 74-79 35371413-8 2022 Our spike protein IgG antibody tests exhibit excellent detection limits in both PBS and human whole blood ((LoD): 1 pg/mL). pbs 80-83 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 4-9 2693495-12 1989 The mean PBS at 24 weeks was 1.48 for PVP-I, 1.62 for H2O2, 1.88 for H2O and 1.34 for PVP-I/H2O2, a reduction from baseline of 31%, 27%, 18%, and 38% respectively. pbs 9-12 H1.5 linker histone, cluster member Homo sapiens 69-78 3195800-2 1988 To identify the mechanism by which PAF-induced bronchoconstriction occurs in humans, bronchoprovocation testing was performed in 7 subjects (3 normal, 4 with mild asthma) after pretreatment with phosphate-buffered saline (PBS), atropine, chlorpheniramine, or indomethacin. pbs 222-225 PCNA clamp associated factor Homo sapiens 35-38 3356043-4 1988 SAMs are generated by subjecting attached cells to a shearing force by rinsing with phosphate-buffered saline (PBS). pbs 111-114 methionine adenosyltransferase 1A Homo sapiens 0-4 3264378-6 1988 Use of phosphate buffered saline (PBS) resulted in higher levels of bacteremia than PBS containing 0.5% bovine serum albumin (PBS-BSA) (P less than 0.001), i.e. the BSA apparently acted to protect the rats from H. influenzae infection. pbs 84-87 albumin Rattus norvegicus 111-124 3264378-6 1988 Use of phosphate buffered saline (PBS) resulted in higher levels of bacteremia than PBS containing 0.5% bovine serum albumin (PBS-BSA) (P less than 0.001), i.e. the BSA apparently acted to protect the rats from H. influenzae infection. pbs 84-87 albumin Rattus norvegicus 111-124 3973981-1 1985 We analyzed the putative tRNA primer binding site (PBS) present in several cloned copies of the murine retrovirus-like VL30 family. pbs 51-54 RIKEN cDNA A130040M12 gene Mus musculus 119-123 3023500-1 1986 The effects of postburn serum (PBS) on the production of colony-stimulating factor (CSF) was evaluated in 13 burned patients by adding PBS to normal peripheral blood mononuclear cells (MNC) and assaying the MNC-conditioned media for CSF content. pbs 31-34 colony stimulating factor 2 Homo sapiens 57-82 3023500-1 1986 The effects of postburn serum (PBS) on the production of colony-stimulating factor (CSF) was evaluated in 13 burned patients by adding PBS to normal peripheral blood mononuclear cells (MNC) and assaying the MNC-conditioned media for CSF content. pbs 31-34 colony stimulating factor 2 Homo sapiens 84-87 3023500-1 1986 The effects of postburn serum (PBS) on the production of colony-stimulating factor (CSF) was evaluated in 13 burned patients by adding PBS to normal peripheral blood mononuclear cells (MNC) and assaying the MNC-conditioned media for CSF content. pbs 135-138 colony stimulating factor 2 Homo sapiens 57-82 3023500-1 1986 The effects of postburn serum (PBS) on the production of colony-stimulating factor (CSF) was evaluated in 13 burned patients by adding PBS to normal peripheral blood mononuclear cells (MNC) and assaying the MNC-conditioned media for CSF content. pbs 135-138 colony stimulating factor 2 Homo sapiens 84-87 3023500-2 1986 PBS inhibited CSF production by at least 50%. pbs 0-3 colony stimulating factor 2 Homo sapiens 14-17 3023500-3 1986 PBS from non-survivors significantly inhibited CSF production more than PBS from survivors. pbs 0-3 colony stimulating factor 2 Homo sapiens 47-50 3023500-4 1986 The addition of lithium chloride restored production of CSF in the presence of day 15 PBS but could not overcome the inhibitory effects of day 1 or day 8 PBS. pbs 86-89 colony stimulating factor 2 Homo sapiens 56-59 3446083-1 1987 CEA and NCA, which behave as dimeric molecules in SDS-polyacrylamide gel electrophoresis, were submitted to gel filtration on the Superose 12HR column in phosphate-buffered saline (PBS) pH 7.0 or in 6 M guanidine hydrochloride. pbs 181-184 CEA cell adhesion molecule 3 Homo sapiens 0-3 3973981-2 1985 In the five VL30 DNA clones analyzed, we identified PBS sequences corresponding to three different tRNA species: tRNAPro, tRNAGly, and tRNAGln. pbs 52-55 RIKEN cDNA A130040M12 gene Mus musculus 12-16 3973981-4 1985 A unique situation was observed in which PBS sequences complementary to two different tRNA species were flanked by otherwise identical VL30 sequences. pbs 41-44 RIKEN cDNA A130040M12 gene Mus musculus 135-139 6540666-3 1984 CST, CS, PR, PS, and PBS yielded 76, 72, 72, 87, and 97% of Vo2 max (PCC) respectively. pbs 21-24 crystallin gamma D Homo sapiens 69-72 34053493-15 2021 (2) Experiment 2: the results of in vitro experiment showed that the mRNA expression of HAVCR2 after high-dose LPS stimulation was down-regulated as compared with PBS group, and the mRNA expression of HAVCR2 in ET group was significantly higher than that in LPS group (2-DeltaDeltaCT: 1.10+-0.10 vs. 0.60+-0.10, P < 0.05). pbs 163-166 hepatitis A virus cellular receptor 2 Mus musculus 88-94 33977872-7 2021 The swelling and weight loss studies in phosphate buffer saline (PBS) indicated a subsequent release of beta-CD from the EMs. pbs 65-68 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 104-111 33949235-1 2021 BACKGROUND: Albumin is important for the transport of protein-bound substances (PBS). pbs 80-83 albumin Homo sapiens 12-19 33949235-5 2021 To evaluate HDx for the improvement of ABiC and removal of PBS, HDx was compared to hemodiafiltration (Fresenius-FX80, HDF). pbs 59-62 highly divergent homeobox Homo sapiens 12-15 33888401-9 2021 On day 6, the mRNA expression level of IL-17A was lower in the skin of fingolimod-treated mice than in that of PBS-treated mice, whereas it was higher in the inguinal lymph nodes of fingolimod-treated mice than in those of PBS-treated mice. pbs 111-114 interleukin 17A Mus musculus 39-45 33888401-9 2021 On day 6, the mRNA expression level of IL-17A was lower in the skin of fingolimod-treated mice than in that of PBS-treated mice, whereas it was higher in the inguinal lymph nodes of fingolimod-treated mice than in those of PBS-treated mice. pbs 223-226 interleukin 17A Mus musculus 39-45 33978756-4 2021 Because the molecular details of the interactions have yet to be defined, we solved the solution structure of the PBS-segment preferentially bound by RHA. pbs 114-117 DExH-box helicase 9 Homo sapiens 150-153 33978756-8 2021 Mutagenesis and phylogenetic analyses provide evidence for conservation of the PBS-segment three-way junction structure that is preferentially bound by RHA in support of efficient reverse transcription, the hallmark step of HIV-1 replication. pbs 79-82 DExH-box helicase 9 Homo sapiens 152-155 34041282-8 2021 The ratio of F4/80-positive macrophages or CD3-positive T lymphocytes area to the lesion area was significantly higher in AngII-PBS than in PBS-PBS, and was significantly decreased in AngII-alphaGC. pbs 128-131 adhesion G protein-coupled receptor E1 Mus musculus 13-18 34041282-8 2021 The ratio of F4/80-positive macrophages or CD3-positive T lymphocytes area to the lesion area was significantly higher in AngII-PBS than in PBS-PBS, and was significantly decreased in AngII-alphaGC. pbs 128-131 CD3 antigen, epsilon polypeptide Mus musculus 43-46 34041282-8 2021 The ratio of F4/80-positive macrophages or CD3-positive T lymphocytes area to the lesion area was significantly higher in AngII-PBS than in PBS-PBS, and was significantly decreased in AngII-alphaGC. pbs 140-143 adhesion G protein-coupled receptor E1 Mus musculus 13-18 34041282-8 2021 The ratio of F4/80-positive macrophages or CD3-positive T lymphocytes area to the lesion area was significantly higher in AngII-PBS than in PBS-PBS, and was significantly decreased in AngII-alphaGC. pbs 140-143 CD3 antigen, epsilon polypeptide Mus musculus 43-46 33678101-1 2021 Purpose: This pilot feasibility study aimed to gain preliminary insight into the acceptability and usefulness of the FAB-PBS program for providing behavior support to families following acquired brain injury (ABI) in community settings. pbs 121-124 FA complementation group B Homo sapiens 117-120 33678101-2 2021 The FAB-PBS program is based on a Positive Behavior Support (PBS) framework and principles of Family-Centered Care and Family-Directed Intervention. pbs 8-11 FA complementation group B Homo sapiens 4-7 33678101-4 2021 Findings also suggested an increase in desired behaviors and a decrease in challenging behaviors presented by family members with ABI.Conclusions: The FAB-PBS program may be an acceptable and feasible approach to increasing the capability of family caregivers in providing behavior support following ABI. pbs 155-158 FA complementation group B Homo sapiens 151-154 34053493-15 2021 (2) Experiment 2: the results of in vitro experiment showed that the mRNA expression of HAVCR2 after high-dose LPS stimulation was down-regulated as compared with PBS group, and the mRNA expression of HAVCR2 in ET group was significantly higher than that in LPS group (2-DeltaDeltaCT: 1.10+-0.10 vs. 0.60+-0.10, P < 0.05). pbs 163-166 hepatitis A virus cellular receptor 2 Mus musculus 201-207 33731683-3 2021 In this study, we investigated Ddx6, an essential component of processing bodies (PBs) that executes RNA decay and translational repression in the cytoplasm and participates in the cellular transition of reprogramming. pbs 82-85 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 Mus musculus 31-35 33731683-4 2021 Upon adipogenic induction, Ddx6 dynamically accumulated to form PBs with a binding partner, 4E-T, at the early phase prior to emergence of intracellular lipid droplets. pbs 64-67 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 Mus musculus 27-31 33128181-8 2021 From the TEM data, we showed the fibril spacing of SPEG samples was more similar to fresh control than PBS. pbs 103-106 striated muscle enriched protein kinase Homo sapiens 51-55 33039554-3 2021 Tpk2 and Tpk3 isoforms localize to PBs upon glucose starvation showing different mechanisms and kinetics of accumulation. pbs 35-38 cAMP-dependent protein kinase catalytic subunit TPK2 Saccharomyces cerevisiae S288C 0-4 33566163-8 2021 Intra-peritoneal injections of PBS or hAFSC-EV were given on P6-7. pbs 31-34 CD33 molecule Homo sapiens 61-65 33470868-4 2021 Our results proved that 8-oxo-Gsn rather than 8-oxo-dGsn was significantly increased after challenged with V. parahaemolyticus in urine and tissue samples of SD rats compared with the PBS control group. pbs 184-187 gelsolin Rattus norvegicus 30-33 33572333-6 2021 The fluorescence titration of 2b (10 mM) with Cd2+ showed that the limit of detection (LOD) of the Cd2+-selective 2b was 158 nM in PBS (phosphate-buffered saline) (10 mM, pH 7.2) containing 50% MeOH. pbs 131-134 CD2 molecule Homo sapiens 99-102 33161292-4 2021 For this purpose, two different PBs derived from Albumin Binding Domain (ABDwt) of streptococcal protein G, so called REX and ARS ligands with proved high affinity and selectivity to the human interleukin-23 (IL-23R) and IL-17 receptor A were used. pbs 32-35 RIEG2 Homo sapiens 126-129 33161292-4 2021 For this purpose, two different PBs derived from Albumin Binding Domain (ABDwt) of streptococcal protein G, so called REX and ARS ligands with proved high affinity and selectivity to the human interleukin-23 (IL-23R) and IL-17 receptor A were used. pbs 32-35 interleukin 37 Homo sapiens 193-207 33161292-4 2021 For this purpose, two different PBs derived from Albumin Binding Domain (ABDwt) of streptococcal protein G, so called REX and ARS ligands with proved high affinity and selectivity to the human interleukin-23 (IL-23R) and IL-17 receptor A were used. pbs 32-35 interleukin 23 receptor Homo sapiens 209-215 33161292-4 2021 For this purpose, two different PBs derived from Albumin Binding Domain (ABDwt) of streptococcal protein G, so called REX and ARS ligands with proved high affinity and selectivity to the human interleukin-23 (IL-23R) and IL-17 receptor A were used. pbs 32-35 interleukin 17 receptor A Homo sapiens 221-237 33419925-2 2021 Positively selected GC B cells recirculate between LZs and dark zones (DZs) and ultimately differentiate into plasmablasts (PBs) and memory B cells (MBCs). pbs 124-127 natriuretic peptide receptor 2 Homo sapiens 20-24 33283832-6 2021 Moreover, label-free, continuous, and selective measurement of S. aureus in 0.01x PBS was demonstrated, showing good linearity between the relative changes in electrical conductance of the SWCNTs and logarithmic S. aureus concentrations, a capture/detection time of 35 min, and a limit of detection of 150 CFU mL-1, as well as high specificity through electrical manipulation and biological interaction. pbs 82-85 L1 cell adhesion molecule Mus musculus 310-314 33039554-3 2021 Tpk2 and Tpk3 isoforms localize to PBs upon glucose starvation showing different mechanisms and kinetics of accumulation. pbs 35-38 cAMP-dependent protein kinase catalytic subunit TPK3 Saccharomyces cerevisiae S288C 9-13 33218690-6 2021 PBS was injected into the bulla in the AR and control groups. pbs 0-3 ferredoxin reductase Mus musculus 39-41 32889490-6 2020 The sAA activity was relatively stable if saliva samples were diluted with a NaCl solution or PBS in glass tubes. pbs 94-97 serum amyloid A1 cluster Homo sapiens 4-7 33379854-31 2020 (4) After 24 hours of culture, the phosphorylation levels of Akt of cells in simple NE group and propranolol+ NE group were significantly higher than the level in PBS group (t=8.186, 5.996, P<0.01). pbs 163-166 thymoma viral proto-oncogene 1 Mus musculus 61-64 33238687-23 2020 (2) After 48 hours of culture, Western blotting detection showed that the expression of FAS protein in cells in high glucose alone group was significantly less than that in PBS control group, and the expressions of FAS protein in cells in high glucose+ 5 mug/mL maggot ES group and high glucose+ 10 mug/mL maggot ES group were significantly higher than the expression in high glucose alone group. pbs 173-176 fatty acid synthase Homo sapiens 88-91 33105942-30 2020 The protein expression of IGF-I in the epidermis tissue of wound margin of mice in DETC group was significantly higher than that in PBS group (t=11.71, P<0.01). pbs 132-135 insulin-like growth factor 1 Mus musculus 26-31 33105942-31 2020 (3) On PID 3, the percentage of DETCs expressing IGF-I in the epidermis tissue of wound margin of mice in PBS group was significantly lower than that in WT control group and DETC group (t=24.95, 27.23, P<0.01). pbs 106-109 insulin-like growth factor 1 Mus musculus 49-54 33105942-32 2020 (4) On PID 12, the number of keratin 15 positive cells in the epidermis tissue of wound margin of mice in PBS group was significantly lower than that in WT control group, DETC group, and IGF-I group (t=17.97, 11.95, 7.63, P<0.01). pbs 106-109 keratin 15 Mus musculus 29-39 33105942-32 2020 (4) On PID 12, the number of keratin 15 positive cells in the epidermis tissue of wound margin of mice in PBS group was significantly lower than that in WT control group, DETC group, and IGF-I group (t=17.97, 11.95, 7.63, P<0.01). pbs 106-109 insulin-like growth factor 1 Mus musculus 187-192 33105942-33 2020 (5) The number of keratin 10 positive cells in the epidermis tissue of wound margin of mice in PBS group was significantly higher than that in WT control group, DETC group, and IGF-I group (t=11.59, 9.51, 3.48, P<0.05 or P<0.01). pbs 95-98 keratin 10 Mus musculus 18-28 33105944-12 2020 Results: (1) After culture of 6 hours, compared with those in PBS control group, the expression levels of IL-1beta and IL-23 mRNA in cells in IL-17A stimulation group were significantly increased (t=13.46, 6.72, P<0.01). pbs 62-65 interleukin 1 alpha Mus musculus 106-114 33105944-12 2020 Results: (1) After culture of 6 hours, compared with those in PBS control group, the expression levels of IL-1beta and IL-23 mRNA in cells in IL-17A stimulation group were significantly increased (t=13.46, 6.72, P<0.01). pbs 62-65 interleukin 23, alpha subunit p19 Mus musculus 119-124 33105944-12 2020 Results: (1) After culture of 6 hours, compared with those in PBS control group, the expression levels of IL-1beta and IL-23 mRNA in cells in IL-17A stimulation group were significantly increased (t=13.46, 6.72, P<0.01). pbs 62-65 interleukin 17A Mus musculus 142-148 32923485-8 2020 Furthermore, the mRNA expression of tumour necrosis factor-alpha (TNF-alpha) and the receptor activator of nuclear factor kappa-B ligand (RANKL) were decreased in DPP-4 inhibitor-treated mice compared with those receiving PBS and control animals. pbs 222-225 tumor necrosis factor Mus musculus 66-75 33116526-8 2020 Patients with PBS with right-side symptoms showed right-side-predominant rCBF asymmetry in the parietal region and left-side-predominant rCBF asymmetry in the thalamus, and vice versa. pbs 14-17 CCAAT/enhancer binding protein zeta Rattus norvegicus 73-77 33116526-8 2020 Patients with PBS with right-side symptoms showed right-side-predominant rCBF asymmetry in the parietal region and left-side-predominant rCBF asymmetry in the thalamus, and vice versa. pbs 14-17 CCAAT/enhancer binding protein zeta Rattus norvegicus 137-141 33116526-11 2020 There are two types of symmetrical and asymmetrical rCBF patterns in the pathophysiology of PBS despite similar clinical manifestations. pbs 92-95 CCAAT/enhancer binding protein zeta Rattus norvegicus 52-56 33277869-9 2020 Rescue experimental results manifested that insulin-like growth factor 1 (IGF-1) supplementation remarkably elevated the expressions of PI3K, p-Akt and p-mTOR compared with phosphate-buffered saline (PBS) supplementation. pbs 200-203 insulin like growth factor 1 Homo sapiens 44-72 33277869-9 2020 Rescue experimental results manifested that insulin-like growth factor 1 (IGF-1) supplementation remarkably elevated the expressions of PI3K, p-Akt and p-mTOR compared with phosphate-buffered saline (PBS) supplementation. pbs 200-203 insulin like growth factor 1 Homo sapiens 74-79 32799354-2 2020 Mean axial elongation was reduced in the eyes injected with the EGF/EGFR-antibody compared with the contralateral control eyes injected with PBS (phosphate-buffered solution) (0.43 +- 0.13 mm vs 0.53 +- 0.13 mm; P < .001). pbs 141-144 pro-epidermal growth factor Cavia porcellus 64-67 32992901-5 2020 Later, TDP-43 foci associate less with SGs and more with PBs, though independent TDP-43 foci also accumulate. pbs 57-60 TAR DNA binding protein Homo sapiens 7-13 32479341-4 2020 The electrical resistance of the sensor varied linearly (R2 = 0.986) with respect to concentrations of the target miRNA-21 in the range from 10 pM to 100 nM in phosphate-buffered saline (PBS); the limit of detection was 14.6 pM. pbs 187-190 microRNA 21 Homo sapiens 114-122 32923485-8 2020 Furthermore, the mRNA expression of tumour necrosis factor-alpha (TNF-alpha) and the receptor activator of nuclear factor kappa-B ligand (RANKL) were decreased in DPP-4 inhibitor-treated mice compared with those receiving PBS and control animals. pbs 222-225 tumor necrosis factor (ligand) superfamily, member 11 Mus musculus 138-143 32923485-8 2020 Furthermore, the mRNA expression of tumour necrosis factor-alpha (TNF-alpha) and the receptor activator of nuclear factor kappa-B ligand (RANKL) were decreased in DPP-4 inhibitor-treated mice compared with those receiving PBS and control animals. pbs 222-225 dipeptidylpeptidase 4 Mus musculus 163-168 32265078-12 2020 Compared to PBS-injected mice, they displayed a dramatic decrease in glomerular deposits of IgG, C1q and PTX3, as well as in the amount of EDD (p = 0.006) and podocyte effacement (p = 0.043). pbs 12-15 pentraxin related gene Mus musculus 105-109 32922594-2 2020 Current reports have assessed the toxicity of oligomeric alpha-Syn (o-alpha-Syn) mostly in vitro after the incubation with PBS, which leaves o-alpha-Syn non-phosphorylated and does not reflect actual physiologic conditions in PD patients. pbs 123-126 synemin Homo sapiens 63-66 32922594-2 2020 Current reports have assessed the toxicity of oligomeric alpha-Syn (o-alpha-Syn) mostly in vitro after the incubation with PBS, which leaves o-alpha-Syn non-phosphorylated and does not reflect actual physiologic conditions in PD patients. pbs 123-126 synemin Homo sapiens 76-79 32752710-12 2020 In the case of the MetHb solution in PBS, the hydration of the solvent ions and their interaction with charges on the protein"s surface are also taken into consideration. pbs 37-40 hemoglobin subunit gamma 2 Homo sapiens 19-24 32527549-5 2020 111In-DOTA-F56 shows good stability in 0.01 M Phosphate Buffered Saline (PBS) and 5% Human Serum Albumin (HSA). pbs 73-76 DLEC1 cilia and flagella associated protein Homo sapiens 11-14 33335764-5 2020 Western blotting and immunofluorescence staining showed that mTFEB protein levels were significantly increased in the brain tissue samples of mice injected with mTFEB-overexpressing vectors compared with those injected with PBS or GFP-overexpressing vectors. pbs 224-227 transcription factor EB Mus musculus 61-66 32443803-6 2020 Using GPS-PBS, we predicted 371,018 mammalian p-sites that potentially interact with at least one PPBD, and revealed that various PPBD-containing proteins (PPCPs) and protein kinases (PKs) can simultaneously regulate the same p-sites to orchestrate important pathways, such as the PI3K-Akt signaling pathway. pbs 10-13 AKT serine/threonine kinase 1 Homo sapiens 286-289 32250935-8 2020 Differential pulse voltammetry (DPV) analysis detected 3 CFU mL-1 and 5 CFU mL-1 of S. aureus in phosphate buffer saline (PBS) and milk, respectively, within 30 min at neutral pH and showed stability over 6-weeks at 4 C. The biosensor showed high specificity for S. aureus, both in pure and mixed cultures of non-host bacteria, and effectively discriminated live S. aureus in a mixture of live/dead cells. pbs 122-125 2'-5' oligoadenylate synthetase 1B Mus musculus 61-71 32336543-6 2020 Furthermore, quantitative real-time polymerase chain reaction (qRT-PCR) and enzyme-linked immunosorbent assay (ELISA) analyses revealed that ApoL1-treated mice exhibited enhanced expression of various inflammation markers in the kidney and serum compared to the PBS-treated mice. pbs 262-265 apolipoprotein L1 Homo sapiens 141-146 32599804-4 2020 The limit of detection (LOD) was achieved in a range of 100 ng mL-1 and 1 fg mL-1 in both phosphate buffered saline (PBS) and human serum (hs). pbs 117-120 L1 cell adhesion molecule Mus musculus 63-73 32599804-4 2020 The limit of detection (LOD) was achieved in a range of 100 ng mL-1 and 1 fg mL-1 in both phosphate buffered saline (PBS) and human serum (hs). pbs 117-120 L1 cell adhesion molecule Mus musculus 63-67 32599804-5 2020 Furthermore, a significant change in the electrochemical impedance from 45% to 70% (hs) and 38% to 60% (PBS) over the loading range of CRP was achieved. pbs 104-107 C-reactive protein Homo sapiens 135-138 32547538-4 2020 We found that Hspa13 mRNA was increased in PCs from atacicept-treated lupus-prone mice and in LPS-stimulated plasmablasts (PBs) and PCs. pbs 123-126 heat shock protein 70 family, member 13 Mus musculus 14-20 32547538-5 2020 A critical finding was that PBs and PCs [but not naive B cells and germinal center (GC) B cells] expressed high levels of Hspa13. pbs 28-31 heat shock protein 70 family, member 13 Mus musculus 122-128 32258829-4 2020 And its degradation behavior in phosphate buffer saline (PBS) containing bovine serum albumin (BSA) was investigated and compared with that of the uncoated alloy. pbs 57-60 albumin Homo sapiens 80-93 32456371-20 2020 (5) On ID 7, p62 mRNA expression in the skin tissue of mice in bleomycin group was significantly lower than that in simple PBS group (t=0.93, P<0.05). pbs 123-126 nucleoporin 62 Mus musculus 13-16 32456371-22 2020 On ID 28, the mRNA expressions of p62 and Beclin-1 in the skin tissue of mice in bleomycin group were significantly lower than those in blank control group (t=0.50, 0.44, P<0.05) and simple PBS group (t=0.97, 0.55, P<0.05), and that of LC3 II was significantly higher than that in blank control group and simple PBS group, respectively (t=0.51, 0.98, P <0.01). pbs 190-193 nucleoporin 62 Mus musculus 34-37 32456371-22 2020 On ID 28, the mRNA expressions of p62 and Beclin-1 in the skin tissue of mice in bleomycin group were significantly lower than those in blank control group (t=0.50, 0.44, P<0.05) and simple PBS group (t=0.97, 0.55, P<0.05), and that of LC3 II was significantly higher than that in blank control group and simple PBS group, respectively (t=0.51, 0.98, P <0.01). pbs 190-193 beclin 1, autophagy related Mus musculus 42-50 32456371-22 2020 On ID 28, the mRNA expressions of p62 and Beclin-1 in the skin tissue of mice in bleomycin group were significantly lower than those in blank control group (t=0.50, 0.44, P<0.05) and simple PBS group (t=0.97, 0.55, P<0.05), and that of LC3 II was significantly higher than that in blank control group and simple PBS group, respectively (t=0.51, 0.98, P <0.01). pbs 312-315 nucleoporin 62 Mus musculus 34-37 32456371-24 2020 On ID 14, the protein expressions of p62 and Beclin-1 in the skin tissue of mice in bleomycin group were significantly higher than those in blank control group (t=0.86, 0.89, P<0.05) and simple PBS group (t=0.42, 0.89, P<0.05). pbs 194-197 nucleoporin 62 Mus musculus 37-40 32456371-24 2020 On ID 14, the protein expressions of p62 and Beclin-1 in the skin tissue of mice in bleomycin group were significantly higher than those in blank control group (t=0.86, 0.89, P<0.05) and simple PBS group (t=0.42, 0.89, P<0.05). pbs 194-197 beclin 1, autophagy related Mus musculus 45-53 32384631-10 2020 This experimental evidence shows that the ADH biosensor is ultrasensitive and highly selective towards ADH in PBS buffer and ADH-spiked in human serum. pbs 110-113 arginine vasopressin Homo sapiens 42-45 32384631-10 2020 This experimental evidence shows that the ADH biosensor is ultrasensitive and highly selective towards ADH in PBS buffer and ADH-spiked in human serum. pbs 110-113 arginine vasopressin Homo sapiens 103-106 32384631-10 2020 This experimental evidence shows that the ADH biosensor is ultrasensitive and highly selective towards ADH in PBS buffer and ADH-spiked in human serum. pbs 110-113 arginine vasopressin Homo sapiens 103-106 31350800-6 2020 Alkaline phosphatase (ALP) activity in cell constructs was maintained by freeze drying in 10% sucrose-containing PBS, whereas cell constructs treated with PBS without sucrose or with sucrose-containing SCB showed significant reductions of ALP activity. pbs 113-116 alkaline phosphatase, placental Homo sapiens 0-20 31350800-6 2020 Alkaline phosphatase (ALP) activity in cell constructs was maintained by freeze drying in 10% sucrose-containing PBS, whereas cell constructs treated with PBS without sucrose or with sucrose-containing SCB showed significant reductions of ALP activity. pbs 113-116 alkaline phosphatase, placental Homo sapiens 22-25 31350800-6 2020 Alkaline phosphatase (ALP) activity in cell constructs was maintained by freeze drying in 10% sucrose-containing PBS, whereas cell constructs treated with PBS without sucrose or with sucrose-containing SCB showed significant reductions of ALP activity. pbs 155-158 alkaline phosphatase, placental Homo sapiens 239-242 32241050-27 2020 (7) On the 8th day post transplantation, the percentages of CD4(+) CD25(+) Foxp3(+) Treg in spleen of mice in BMSCs alone group and BMSCs+ IL-17 group were significantly higher than the percentage of PBS control group (P<0.01), and the percentage of CD4(+) CD25(+) Foxp3(+) Treg in spleen of mice in BMSCs+ IL-17 group was significantly higher than that of BMSCs alone group (P<0.01). pbs 200-203 CD4 antigen Mus musculus 60-63 33480731-2 2020 Despite intensive study over the years, the correlation between the structural properties of NPs (or PBs) and the NP-PB interactions is still to be well unveiled. pbs 101-104 natriuretic peptide B Homo sapiens 114-119 32193477-8 2020 The electrochemical assessment demonstrates that the ZnO/PIn-MWCNT/Frt/GOx nanobiocatalyst exhibits much higher electrocatalytic activity towards the oxidation of glucose with a maximum current density of 4.9 mA cm-2 by consuming 50 mM glucose concentration in phosphate buffer saline (PBS) (pH 7.4) as the testing solution by applying 100 mVs-1 scan rates. pbs 286-289 hydroxyacid oxidase 1 Homo sapiens 71-74 32309171-9 2020 LRG1 group upregulated the levels of VEGF and the vascular endothelial growth factor receptor (VEGFR) family when compared with the phosphate-buffered saline (PBS) control group. pbs 159-162 leucine-rich alpha-2-glycoprotein 1 Mus musculus 0-4 33480731-9 2020 Our work not only helps us to understand the applicability of previous theories on the NP-PB system but also reveals the key factors that impact the NP-PB interaction in a series of probable conditions, which may provide valuable guidelines for designing and engineering novel nanomaterials based on functional NPs and PBs. pbs 319-322 natriuretic peptide B Homo sapiens 149-154 31891812-9 2020 Although a high amount of biological variability in response to pIC was evident across all treatments, rearing temperature significantly influenced transcript abundance and/or fold-changes comparing time- and temperature-matched pIC- and PBS-injected fish for several genes (tlr3, lgp2, stat1b, isg15a, rsad2 and ifng) at 24 hpi. pbs 238-241 toll-like receptor 3 Salmo salar 275-279 29985056-11 2020 A statistically significant difference was observed in the NAC 1 mM group compared with the PBS group ( P = 0.0255). pbs 92-95 nucleus accumbens associated 1 Homo sapiens 59-64 32275005-6 2020 RESULTS: Compared with the PBS group, the levels of LDH and inflammatory factors such as interleukin (IL-1beta, IL-18) and tumor necrosis factor-alpha (TNF-alpha) were significantly increased after LPS stimulation group. pbs 27-30 interleukin 1 alpha Mus musculus 102-110 32275005-6 2020 RESULTS: Compared with the PBS group, the levels of LDH and inflammatory factors such as interleukin (IL-1beta, IL-18) and tumor necrosis factor-alpha (TNF-alpha) were significantly increased after LPS stimulation group. pbs 27-30 tumor necrosis factor Mus musculus 152-161 31545380-8 2019 RESULTS: The OMOP-CDM mappings identified 2.6%, 15.2%, and 24.4% more drugs than the PBS mappings in the A10, N02A and N06A groups respectively. pbs 85-88 immunoglobulin kappa variable 6D-21 (non-functional) Homo sapiens 105-108 31751251-11 2019 The overall sensor system successfully detects the VEGF in both phosphate-buffered saline (PBS) and human blood serum. pbs 91-94 vascular endothelial growth factor A Homo sapiens 51-55 31751251-12 2019 Without the use of precision instruments, this work achieves a resolution of 15 fM [Formula: see text] in range of 0.1 to 1000 pM and denotes the clear VEGF selectivity at 40x in PBS and 5x in the blood serum compared to other proteins (IgG, Con A, and cholera toxin). pbs 179-182 vascular endothelial growth factor A Homo sapiens 152-156 31452481-9 2019 In addition, expression levels of the oestrogen receptor Ealpha/beta (ERalpha, ERbeta) and progesterone receptor (PR) detected by western blot and enzyme-linked immunosorbent assay (ELISA) were higher in the ADSCs group than in the PBS group. pbs 232-235 estrogen receptor 1 Rattus norvegicus 70-77 31452481-9 2019 In addition, expression levels of the oestrogen receptor Ealpha/beta (ERalpha, ERbeta) and progesterone receptor (PR) detected by western blot and enzyme-linked immunosorbent assay (ELISA) were higher in the ADSCs group than in the PBS group. pbs 232-235 estrogen receptor 2 Rattus norvegicus 79-85 31452481-9 2019 In addition, expression levels of the oestrogen receptor Ealpha/beta (ERalpha, ERbeta) and progesterone receptor (PR) detected by western blot and enzyme-linked immunosorbent assay (ELISA) were higher in the ADSCs group than in the PBS group. pbs 232-235 progesterone receptor Rattus norvegicus 91-112 31385067-2 2019 The interaction of dinuclear Pd1-Pd3 complexes with calf thymus DNA (CT-DNA) has been monitored by viscosity measurements, UV-Vis and fluorescence emission spectroscopy in aqueous phosphate buffer solution (PBS) at pH 7.40 and 37 C. In addition, these experimental conditions have been applied to investigate the binding affinities of Pd1-Pd3 complexes to the bovine serum albumin (BSA) by fluorescence emission spectroscopy. pbs 207-210 programmed cell death 1 Bos taurus 29-32 31647203-12 2019 The expression of Jak1 and Jak3 mRNA and pSTAT3, MMP2 and MMP9 proteins in the anti-IL-9 group was lower than that of the PBS or IgG groups (p < 0.05), but the STAT3 and VEGF protein levels showed no significant difference (p < 0.05). pbs 122-125 Janus kinase 1 Mus musculus 18-22 31504691-4 2019 Pick bodies (PBs) positive for Bodian and Bielshowsky staining and 3-repeat-tau were detected in frontal and temporal lobes and limbic regions. pbs 13-16 protein interacting with PRKCA 1 Homo sapiens 0-4 29447086-6 2019 Results: The expression of IL-17, IL-23 P19, IL-23 P40, CCL20, CCL22 and CCR4 in spinal cord and serum IL-17 and IL-23 levels in PBS-administrated EAE mice were significantly increased compared with healthy group. pbs 129-132 interleukin 17A Mus musculus 27-32 29447086-6 2019 Results: The expression of IL-17, IL-23 P19, IL-23 P40, CCL20, CCL22 and CCR4 in spinal cord and serum IL-17 and IL-23 levels in PBS-administrated EAE mice were significantly increased compared with healthy group. pbs 129-132 chemokine (C-C motif) ligand 20 Mus musculus 56-61 29447086-6 2019 Results: The expression of IL-17, IL-23 P19, IL-23 P40, CCL20, CCL22 and CCR4 in spinal cord and serum IL-17 and IL-23 levels in PBS-administrated EAE mice were significantly increased compared with healthy group. pbs 129-132 chemokine (C-C motif) ligand 22 Mus musculus 63-68 29447086-6 2019 Results: The expression of IL-17, IL-23 P19, IL-23 P40, CCL20, CCL22 and CCR4 in spinal cord and serum IL-17 and IL-23 levels in PBS-administrated EAE mice were significantly increased compared with healthy group. pbs 129-132 chemokine (C-C motif) receptor 4 Mus musculus 73-77 29447086-6 2019 Results: The expression of IL-17, IL-23 P19, IL-23 P40, CCL20, CCL22 and CCR4 in spinal cord and serum IL-17 and IL-23 levels in PBS-administrated EAE mice were significantly increased compared with healthy group. pbs 129-132 interleukin 17A Mus musculus 103-108 31328366-2 2019 Here, we report the cases of three CF-negative children, who carry rare mutations in the CF transmembrane conductance regulator (CFTR) gene, and, for whom, PBS was the only manifestation of CFTR protein dysfunction. pbs 156-159 CF transmembrane conductance regulator Homo sapiens 89-127 31328366-2 2019 Here, we report the cases of three CF-negative children, who carry rare mutations in the CF transmembrane conductance regulator (CFTR) gene, and, for whom, PBS was the only manifestation of CFTR protein dysfunction. pbs 156-159 CF transmembrane conductance regulator Homo sapiens 129-133 31328366-2 2019 Here, we report the cases of three CF-negative children, who carry rare mutations in the CF transmembrane conductance regulator (CFTR) gene, and, for whom, PBS was the only manifestation of CFTR protein dysfunction. pbs 156-159 CF transmembrane conductance regulator Homo sapiens 190-194 31328366-11 2019 CONCLUSION: We suggest that PBS as the sole manifestation of CFTR dysfunction might be considered a CFTR-related disorder of infancy. pbs 28-31 CF transmembrane conductance regulator Homo sapiens 61-65 31771729-7 2019 RESULTS: Compared with the PBS control group, the MCP-1 mRNA expression significantly increased at 6 hours and 12 hours after LPS stimulation and peaked at 6 hours, then decreased gradually, but remained significantly higher than the PBS control group at 12 hours [2-DeltaDeltaCt: 16.41 (15.03, 18.00) vs. 1.00 (0.80, 1.26) at 6 hours, 9.27 (8.11, 9.85) vs. 1.00 (0.84, 1.20) at 12 hours, both P < 0.05]. pbs 27-30 C-C motif chemokine ligand 2 Homo sapiens 50-55 31771729-7 2019 RESULTS: Compared with the PBS control group, the MCP-1 mRNA expression significantly increased at 6 hours and 12 hours after LPS stimulation and peaked at 6 hours, then decreased gradually, but remained significantly higher than the PBS control group at 12 hours [2-DeltaDeltaCt: 16.41 (15.03, 18.00) vs. 1.00 (0.80, 1.26) at 6 hours, 9.27 (8.11, 9.85) vs. 1.00 (0.84, 1.20) at 12 hours, both P < 0.05]. pbs 234-237 C-C motif chemokine ligand 2 Homo sapiens 50-55 31210331-8 2019 According to the WB results, the protein expression levels of beta-catenin and Wnt3a in exosome treatment group were significantly higher than those in the blank control group and PBS injection group (p<0.01). pbs 180-183 catenin beta 1 Rattus norvegicus 62-74 30464333-11 2019 MMP-2 and MMP-9 in BALF and CTGF, TGF-beta, and TSLP in lungs significantly decreased in OVA + anti-TSLP and PBS groups compared with OVA group. pbs 109-112 matrix metallopeptidase 2 Homo sapiens 0-5 30464333-11 2019 MMP-2 and MMP-9 in BALF and CTGF, TGF-beta, and TSLP in lungs significantly decreased in OVA + anti-TSLP and PBS groups compared with OVA group. pbs 109-112 matrix metallopeptidase 9 Homo sapiens 10-15 30464333-11 2019 MMP-2 and MMP-9 in BALF and CTGF, TGF-beta, and TSLP in lungs significantly decreased in OVA + anti-TSLP and PBS groups compared with OVA group. pbs 109-112 cellular communication network factor 2 Homo sapiens 28-32 30464333-11 2019 MMP-2 and MMP-9 in BALF and CTGF, TGF-beta, and TSLP in lungs significantly decreased in OVA + anti-TSLP and PBS groups compared with OVA group. pbs 109-112 transforming growth factor alpha Homo sapiens 34-42 30464333-11 2019 MMP-2 and MMP-9 in BALF and CTGF, TGF-beta, and TSLP in lungs significantly decreased in OVA + anti-TSLP and PBS groups compared with OVA group. pbs 109-112 thymic stromal lymphopoietin Mus musculus 48-52 31422817-1 2019 The human RNA helicase DDX6 is an essential component of membrane-less organelles called processing bodies (PBs). pbs 108-111 helicase for meiosis 1 Homo sapiens 14-22 31422817-1 2019 The human RNA helicase DDX6 is an essential component of membrane-less organelles called processing bodies (PBs). pbs 108-111 DEAD-box helicase 6 Homo sapiens 23-27 31539106-16 2019 The results of the biomechanical test of femur specimens at 7 weeks after operation showed that in miR-25 mimics group, the maximum load, fracture energy and stiffness increased by 188%, 333% and 90%, respectively, compared with those in the PBS group (p<0.01). pbs 242-245 microRNA 25 Rattus norvegicus 99-105 31142572-4 2019 Immunohistochemical staining revealed that the BDNF-injected group had a significant increase in the level of synaptophysin, which is a presynaptic vesicle protein, in the innermost IPL compared with the phosphate-buffered saline (PBS)-injected group. pbs 231-234 brain-derived neurotrophic factor Rattus norvegicus 47-51 31105058-6 2019 The fraction of PAC-1 binding to fXe-PLTs suspended in either phosphate-buffered saline (PBS) or plasma was larger than that to Aph-PLTs in a resting state. pbs 89-92 dual specificity phosphatase 2 Homo sapiens 16-21 30955246-4 2019 Next, we successfully established tibia fracture (TF) models of C57BL/6J and Col2a1-ICAT mice and the effect of silencing lncRNA MEG3 on fracture healing was detected after TF mice were treated with phosphate buffer saline (PBS), MEG3 siRNA and scramble siRNA. pbs 224-227 maternally expressed 3 Mus musculus 129-133 31131155-6 2019 Results: Mice cohorts injected with untargeted or ICAM2-targeted GNR demonstrated increased lesion-associated photothermal signal during subsequent imaging relative to phosphate-buffered saline (PBS)-injected controls. pbs 195-198 intercellular adhesion molecule 2 Mus musculus 50-55 31133639-3 2019 The alpha-isoform of PI3K which is a pivotal modulator of PI3K/AKT/mTOR signaling pathway, responsible for neurological disorders like epilepsy, found as a potential target molecule against these 17 semi-synthesized PBS compounds using in silico ligand-based pharmacophore mapping and target screening. pbs 216-219 mechanistic target of rapamycin kinase Danio rerio 67-71 30407111-6 2018 RESULTS: Box A versus PBS prophylactic treatment significantly reduced clinical scores, MPO activity, bacterial load, and expression of TLR4, RAGE, IL-1beta, CXCL2, and TNF-alpha in the infected cornea. pbs 22-25 myeloperoxidase Mus musculus 88-91 30716195-3 2019 Density functional theory calculations and experimental results reveal that the electron transfer from CoP to Co-MOF through N-P/N-Co bonds could lead to the optimized adsorption energy of H2 O (DeltaG H 2 O * ) and hydrogen (DeltaGH* ), which, together with the unique porous structure of Co-MOF, contributes to the remarkable HER performance with an overpotential of 49 mV at a current density of 10 mA cm-2 in 1 m phosphate buffer solution (PBS, pH 7.0). pbs 448-451 caspase recruitment domain family member 16 Homo sapiens 103-106 30683555-5 2019 18F-CA IX-P1-4-10 had good stability in phosphate buffered saline (PBS), but about 51% peptide degradation was detected in new-born calf serum (NBCS) after incubation. pbs 67-70 carbonic anhydrase 9 Homo sapiens 4-9 30648970-6 2019 Overall, our results uncover a function of Pat1 in promoting the multimerization of Dhh1 on mRNA, thereby aiding the assembly of large multivalent mRNP granules that are PBs. pbs 170-173 amyloid beta precursor protein binding protein 2 Homo sapiens 43-47 30799470-7 2019 The use of Centrix or endo tip reduced the porosity and increased the PBS in the apical third compared with the use of endodontic files. pbs 70-73 TOR signaling pathway regulator Homo sapiens 27-30 32655858-2 2019 Diffusion through the proteinaceous ASM yielded a significantly lower diffusion coefficient compared to PBS, which is attributed to both the physical obstruction by the mucin mesh and reactive nature of NO radicals towards the biological compounds in ASM. pbs 104-107 LOC100508689 Homo sapiens 169-174 30002472-10 2019 RESULTS: The expression of BDNF and TrkB in the SCI-TT/PBS group was 1.46 +- 0.09 and 1.70 +- 0.22, respectively, higher than that in SCI/PBS group (0.51 +- 0.04 and 0.76 +- 0.07, respectively), relative to the Sham group. pbs 55-58 brain-derived neurotrophic factor Rattus norvegicus 27-31 30002472-10 2019 RESULTS: The expression of BDNF and TrkB in the SCI-TT/PBS group was 1.46 +- 0.09 and 1.70 +- 0.22, respectively, higher than that in SCI/PBS group (0.51 +- 0.04 and 0.76 +- 0.07, respectively), relative to the Sham group. pbs 55-58 neurotrophic receptor tyrosine kinase 2 Rattus norvegicus 36-40 30002472-10 2019 RESULTS: The expression of BDNF and TrkB in the SCI-TT/PBS group was 1.46 +- 0.09 and 1.70 +- 0.22, respectively, higher than that in SCI/PBS group (0.51 +- 0.04 and 0.76 +- 0.07, respectively), relative to the Sham group. pbs 138-141 brain-derived neurotrophic factor Rattus norvegicus 27-31 30002472-10 2019 RESULTS: The expression of BDNF and TrkB in the SCI-TT/PBS group was 1.46 +- 0.09 and 1.70 +- 0.22, respectively, higher than that in SCI/PBS group (0.51 +- 0.04 and 0.76 +- 0.07, respectively), relative to the Sham group. pbs 138-141 neurotrophic receptor tyrosine kinase 2 Rattus norvegicus 36-40 30002472-14 2019 The number of NeuN+ neurons, the cell body area of motor neurons, PSD-95, and SYP expression in the SCI-TT/PBS group was significantly higher than that in the SCI/PBS, SCI/TrkB-IgG, and SCI-TT/TrkB-IgG groups. pbs 107-110 synaptophysin Rattus norvegicus 78-81 31083581-7 2019 These results were further verified in metastatic PHEO, where the intratumoral injections of mannan-BAM, toll-like receptor ligands, and anti-CD40 into subcutaneous tumors resulted in significantly less intense bioluminescence signals of liver metastatic lesions induced by tail vein injection compared to the PBS-treated group. pbs 310-313 CD40 antigen Mus musculus 142-146 31070337-5 2019 The B2M sample was analyzed on a TSKgel SuperSW2000 column (30 cmx4.6 mm, 4 mum) by an Agilent 1200 Series HPLC using 0.01 mol/L PBS (pH 7.2-7.4) as the mobile phase at a flow rate of 0.5 mL/min. pbs 129-132 beta-2-microglobulin Homo sapiens 4-7 31070337-10 2019 The limit of quantitation for the B2M monomer in PBS was 0.08 g/L (S/N=10). pbs 49-52 beta-2-microglobulin Homo sapiens 34-37 30979922-6 2019 The relative resistance change of this sensor owing to the attachment of cTnT was quantified as the cTnT concentration decreased from 10 ng/mL to 1 pg/mL in phosphate buffered saline (PBS) and 10-fold diluted human serum in PBS, with the limits of detection being 1.2 pg/mL and 1.7 pg/mL, respectively, which is sufficiently sensitive for clinical applications. pbs 184-187 troponin T2, cardiac type Homo sapiens 73-77 30979922-6 2019 The relative resistance change of this sensor owing to the attachment of cTnT was quantified as the cTnT concentration decreased from 10 ng/mL to 1 pg/mL in phosphate buffered saline (PBS) and 10-fold diluted human serum in PBS, with the limits of detection being 1.2 pg/mL and 1.7 pg/mL, respectively, which is sufficiently sensitive for clinical applications. pbs 184-187 troponin T2, cardiac type Homo sapiens 100-104 30979922-6 2019 The relative resistance change of this sensor owing to the attachment of cTnT was quantified as the cTnT concentration decreased from 10 ng/mL to 1 pg/mL in phosphate buffered saline (PBS) and 10-fold diluted human serum in PBS, with the limits of detection being 1.2 pg/mL and 1.7 pg/mL, respectively, which is sufficiently sensitive for clinical applications. pbs 224-227 troponin T2, cardiac type Homo sapiens 73-77 30947720-1 2019 BACKGROUND: Reverse transcription (RT) of HIV and SIV is initiated by the binding of the acceptor stem of tRNALys3 to the primer binding site (PBS) of the viral RNA genome. pbs 143-146 IV Homo sapiens 50-53 30947720-4 2019 We found that in humans there are low but measurable levels of viral RNA genomes harboring a PBS containing the noncanonical T at position 8 (PBS-Lys5) corresponding to the tRNAlys5 sequence and representing an average of 0.52% (range 0.07-1.6%) of the total viral population. pbs 93-96 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Homo sapiens 146-150 30947720-4 2019 We found that in humans there are low but measurable levels of viral RNA genomes harboring a PBS containing the noncanonical T at position 8 (PBS-Lys5) corresponding to the tRNAlys5 sequence and representing an average of 0.52% (range 0.07-1.6%) of the total viral population. pbs 142-145 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Homo sapiens 146-150 30947720-5 2019 This value is remarkably consistent with the proportion of PBS-Lys5 we identified in a cross-sectional assessment of the LANL HIV database (0.51%). pbs 59-62 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Homo sapiens 63-67 30947720-6 2019 In macaques chronically infected with SIVmac239, the PBS-Lys5 was also detected but at a frequency 1-log less than seen for HIV, with an average of 0.056% (range 0.01-0.09%). pbs 53-56 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Homo sapiens 57-61 30947720-7 2019 At this proportion, PBS-Lys5 was comparable to other transition mutations, making it impossible to determine whether the mutation observed is a result of use of tRNALys5 as an RT primer at very low levels or merely the product of in vitro cDNA synthesis/PCR error. pbs 20-23 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Homo sapiens 24-28 30947720-8 2019 We also identified two novel PBS sequences in HIV and SIV at low levels in vivo corresponding to tRNALys6 and tRNALys1,2, suggesting that these tRNAs may rarely also be used to prime RT. pbs 29-32 IV Homo sapiens 54-57 30947720-9 2019 In vivo reversion of the PBS-Lys5 found in SIVmac239 was rapid and reached background levels by 30 days post-infection. pbs 25-28 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Homo sapiens 29-33 30575930-14 2018 Immunohistochemistry results showed a significant deposition of IL-9+ cells in the lung tissues of the PBS group. pbs 103-106 interleukin 9 Mus musculus 64-68 30575930-15 2018 Meanwhile, the mRNA and protein levels of IL-9, sIL-9R, and p-STAT3 in the PBS group were also remarkably higher than those of the IL-9 antibody group. pbs 75-78 interleukin 9 Mus musculus 42-46 30575930-15 2018 Meanwhile, the mRNA and protein levels of IL-9, sIL-9R, and p-STAT3 in the PBS group were also remarkably higher than those of the IL-9 antibody group. pbs 75-78 Scl/Tal1 interrupting locus Mus musculus 48-51 30575930-15 2018 Meanwhile, the mRNA and protein levels of IL-9, sIL-9R, and p-STAT3 in the PBS group were also remarkably higher than those of the IL-9 antibody group. pbs 75-78 signal transducer and activator of transcription 3 Mus musculus 62-67 30575930-15 2018 Meanwhile, the mRNA and protein levels of IL-9, sIL-9R, and p-STAT3 in the PBS group were also remarkably higher than those of the IL-9 antibody group. pbs 75-78 interleukin 9 Mus musculus 49-53 30463715-12 2018 Negative regulators of beta-adrenergic signaling, G protein-coupled receptor kinase-2, and beta-arrestin 1 and 2 were all upregulated in PBS-treated samples compared to normal control; however, PEG treatment led to decreased expression. pbs 137-140 arrestin, beta 1 Rattus norvegicus 91-112 30407111-6 2018 RESULTS: Box A versus PBS prophylactic treatment significantly reduced clinical scores, MPO activity, bacterial load, and expression of TLR4, RAGE, IL-1beta, CXCL2, and TNF-alpha in the infected cornea. pbs 22-25 toll-like receptor 4 Mus musculus 136-140 30407111-6 2018 RESULTS: Box A versus PBS prophylactic treatment significantly reduced clinical scores, MPO activity, bacterial load, and expression of TLR4, RAGE, IL-1beta, CXCL2, and TNF-alpha in the infected cornea. pbs 22-25 MOK protein kinase Mus musculus 142-146 30407111-6 2018 RESULTS: Box A versus PBS prophylactic treatment significantly reduced clinical scores, MPO activity, bacterial load, and expression of TLR4, RAGE, IL-1beta, CXCL2, and TNF-alpha in the infected cornea. pbs 22-25 interleukin 1 beta Mus musculus 148-156 30407111-6 2018 RESULTS: Box A versus PBS prophylactic treatment significantly reduced clinical scores, MPO activity, bacterial load, and expression of TLR4, RAGE, IL-1beta, CXCL2, and TNF-alpha in the infected cornea. pbs 22-25 chemokine (C-X-C motif) ligand 2 Mus musculus 158-163 30407111-6 2018 RESULTS: Box A versus PBS prophylactic treatment significantly reduced clinical scores, MPO activity, bacterial load, and expression of TLR4, RAGE, IL-1beta, CXCL2, and TNF-alpha in the infected cornea. pbs 22-25 tumor necrosis factor Mus musculus 169-178 30407111-9 2018 Box A versus PBS therapeutic treatment significantly reduced clinical scores, MPO activity, bacterial load, and protein levels of IL-1beta, CXCL2, and IL-6 in the infected cornea. pbs 13-16 myeloperoxidase Mus musculus 78-81 30407111-9 2018 Box A versus PBS therapeutic treatment significantly reduced clinical scores, MPO activity, bacterial load, and protein levels of IL-1beta, CXCL2, and IL-6 in the infected cornea. pbs 13-16 interleukin 1 beta Mus musculus 130-138 30407111-9 2018 Box A versus PBS therapeutic treatment significantly reduced clinical scores, MPO activity, bacterial load, and protein levels of IL-1beta, CXCL2, and IL-6 in the infected cornea. pbs 13-16 chemokine (C-X-C motif) ligand 2 Mus musculus 140-145 30407111-9 2018 Box A versus PBS therapeutic treatment significantly reduced clinical scores, MPO activity, bacterial load, and protein levels of IL-1beta, CXCL2, and IL-6 in the infected cornea. pbs 13-16 interleukin 6 Mus musculus 151-155 29684862-6 2018 The levels of nuclear factor erythroid 2-related factor 2 (Nrf2) and thioredoxin reductase (TrxR1) mRNA were decreased in PBS-treated mice compared with controls but increased remarkably in LBP-treated mice. pbs 122-125 nuclear factor, erythroid derived 2, like 2 Mus musculus 14-57 30200274-8 2018 The detection limit (DL) was calculated in a linear concentration range of 2-10 microg/mL miRNA-34a target, and it was found to be 0.772 microg/mL (109 nM) in phosphate buffer solution (PBS) and 0.826 microg/mL (117 nM) in diluted fetal bovine serum (FBS). pbs 186-189 microRNA 34a Homo sapiens 90-99 29684862-6 2018 The levels of nuclear factor erythroid 2-related factor 2 (Nrf2) and thioredoxin reductase (TrxR1) mRNA were decreased in PBS-treated mice compared with controls but increased remarkably in LBP-treated mice. pbs 122-125 nuclear factor, erythroid derived 2, like 2 Mus musculus 59-63 29684862-6 2018 The levels of nuclear factor erythroid 2-related factor 2 (Nrf2) and thioredoxin reductase (TrxR1) mRNA were decreased in PBS-treated mice compared with controls but increased remarkably in LBP-treated mice. pbs 122-125 thioredoxin reductase 1 Mus musculus 92-97 29684862-7 2018 The mRNA levels of the DNA repair gene Poly (ADP-ribose) polymerase (PARP14) was increased in PBS-treated mice but decreased significantly in the LBP-treated mice. pbs 94-97 poly (ADP-ribose) polymerase family, member 1 Mus musculus 39-67 29684862-7 2018 The mRNA levels of the DNA repair gene Poly (ADP-ribose) polymerase (PARP14) was increased in PBS-treated mice but decreased significantly in the LBP-treated mice. pbs 94-97 poly (ADP-ribose) polymerase family, member 14 Mus musculus 69-75 29925181-18 2018 (3) Cardiac expressions of miR-21, COL1-A1 and COL3-A1 mRNA: The cardiac expressions of miR-21, COL1-A1 mRNA, COL3-A1mRNA in CVMC group and CVMC+isotype control group were markedly higher than those in PBS group (all P<0.05), which were significantly downregulated in CVMC+miR-21 inhibitor group (all P<0.05 vs. CVMC group and CVMC+isotype control group). pbs 202-205 microRNA 21a Mus musculus 27-33 29251403-9 2018 However, conjunctival TNF-alpha level was significantly lower in the rebamipide-treated group compared with the PBS-treated group. pbs 112-115 tumor necrosis factor Mus musculus 22-31 29510552-4 2018 After 1 year of hydrolytic degradation, though monomers coming from the hydrolytic cleavage of PCL diffused towards the PBS medium, the pH was barely affected, and the rGO nanoplatelets mainly remained in the membranes which envisaged low cytotoxic effect. pbs 120-123 PHD finger protein 1 Homo sapiens 95-98 29925181-19 2018 (4) The cardiac expressions of TGF-beta1 and Smad7 protein: The cardiac expressions of TGF-beta1 protein in CVMC group and CVMC+isotype control group were markedly higher, whereas the cardiac Smad7 protein expressions were significantly lower (all P<0.05) than those in PBS group (all P<0.05), these changes could be reversed in CVMC+miR-21 inhibitor group (P<0.05 vs. CVMC group and CVMC+isotype control group). pbs 273-276 SMAD family member 7 Mus musculus 45-50 29925181-19 2018 (4) The cardiac expressions of TGF-beta1 and Smad7 protein: The cardiac expressions of TGF-beta1 protein in CVMC group and CVMC+isotype control group were markedly higher, whereas the cardiac Smad7 protein expressions were significantly lower (all P<0.05) than those in PBS group (all P<0.05), these changes could be reversed in CVMC+miR-21 inhibitor group (P<0.05 vs. CVMC group and CVMC+isotype control group). pbs 273-276 SMAD family member 7 Mus musculus 192-197 29337123-10 2018 The number of terminal deoxynucleotidyl transferase dUTP nick end labeling-positive neuron cells in the spinal cord and the ratio of Bax to Bcl2 were significantly larger (p < 0.05) in the PBS group than in the MSC group. pbs 192-195 DNA nucleotidylexotransferase Rattus norvegicus 14-51 29337123-10 2018 The number of terminal deoxynucleotidyl transferase dUTP nick end labeling-positive neuron cells in the spinal cord and the ratio of Bax to Bcl2 were significantly larger (p < 0.05) in the PBS group than in the MSC group. pbs 192-195 BCL2 associated X, apoptosis regulator Rattus norvegicus 133-136 29337123-10 2018 The number of terminal deoxynucleotidyl transferase dUTP nick end labeling-positive neuron cells in the spinal cord and the ratio of Bax to Bcl2 were significantly larger (p < 0.05) in the PBS group than in the MSC group. pbs 192-195 BCL2, apoptosis regulator Rattus norvegicus 140-144 29460012-9 2018 Staining intensities for ionized calcium-binding adaptor molecule-1 and calcitonin gene-related peptide in rat DRGs of the GDF6 group were significantly lower than those of the PBS group. pbs 177-180 growth differentiation factor 6 Rattus norvegicus 123-127 31044212-3 2017 We compare Australia"s Pharmaceutical Benefits Scheme (PBS) dispensing claims of HER2-positive early breast cancer patients with medicines prescribed and administered to determine the accuracy of dispensing data to identify treatment protocols, number of treatment cycles and durations of therapy. pbs 55-58 erb-b2 receptor tyrosine kinase 2 Homo sapiens 81-85 29487808-6 2018 RESULTS: The OH rats and PBS-injected rats had increased expression levels of Notch1, Bax, caspase-3, and GAP-43, decreased expression levels of Bcl-2, and increased RGC apoptosis, with severer macular edema and RGCs more loosely aligned, when compared with the normal rats. pbs 25-28 notch receptor 1 Rattus norvegicus 78-84 29487808-6 2018 RESULTS: The OH rats and PBS-injected rats had increased expression levels of Notch1, Bax, caspase-3, and GAP-43, decreased expression levels of Bcl-2, and increased RGC apoptosis, with severer macular edema and RGCs more loosely aligned, when compared with the normal rats. pbs 25-28 BCL2 associated X, apoptosis regulator Rattus norvegicus 86-89 29487808-6 2018 RESULTS: The OH rats and PBS-injected rats had increased expression levels of Notch1, Bax, caspase-3, and GAP-43, decreased expression levels of Bcl-2, and increased RGC apoptosis, with severer macular edema and RGCs more loosely aligned, when compared with the normal rats. pbs 25-28 caspase 3 Rattus norvegicus 91-100 29487808-6 2018 RESULTS: The OH rats and PBS-injected rats had increased expression levels of Notch1, Bax, caspase-3, and GAP-43, decreased expression levels of Bcl-2, and increased RGC apoptosis, with severer macular edema and RGCs more loosely aligned, when compared with the normal rats. pbs 25-28 growth associated protein 43 Rattus norvegicus 106-112 29487808-6 2018 RESULTS: The OH rats and PBS-injected rats had increased expression levels of Notch1, Bax, caspase-3, and GAP-43, decreased expression levels of Bcl-2, and increased RGC apoptosis, with severer macular edema and RGCs more loosely aligned, when compared with the normal rats. pbs 25-28 BCL2, apoptosis regulator Rattus norvegicus 145-150 29804359-9 2018 Compared with the PBS injection group, the transplantation group had significant upregulation in the protein expression of HGF and significant downregulation in the protein expression of alpha-SMA (both P < 0.05). pbs 18-21 actin gamma 2, smooth muscle Rattus norvegicus 187-196 29352308-3 2018 The SDS-PAGE and Western blot results confirmed that the rHSA was secreted into the transgenic silkworm cocoon, and the rHSA could be easily extracted with phosphate-buffered saline (PBS). pbs 183-186 CD24 molecule Rattus norvegicus 57-61 29352308-3 2018 The SDS-PAGE and Western blot results confirmed that the rHSA was secreted into the transgenic silkworm cocoon, and the rHSA could be easily extracted with phosphate-buffered saline (PBS). pbs 183-186 CD24 molecule Rattus norvegicus 120-124 29133242-9 2018 The time course of in vivo near-infrared fluorescence imaging of topical EGF gels on the wound sites were consistent with the in vitro release profiles measured with PBS as the release media. pbs 166-169 epidermal growth factor Homo sapiens 73-76 28877986-3 2017 Ssd1 subsequently targets mRNAs acquired in the nucleus either to daughter cells for translation or to stress granules (SGs) and P-bodies (PBs) for mRNA storage or decay. pbs 139-142 mRNA-binding translational repressor SSD1 Saccharomyces cerevisiae S288C 0-4 28860303-3 2017 tRNALys3 must be released from hLysRS in order to anneal to the PBS, and this process is proposed to be facilitated by the interaction of hLysRS with a tRNA-like element (TLE) first identified in the HIV-1 5"-untranslated region (5"-UTR) of the subtype B NL4-3 virus. pbs 64-67 lysyl-tRNA synthetase 1 Homo sapiens 31-37 28860303-3 2017 tRNALys3 must be released from hLysRS in order to anneal to the PBS, and this process is proposed to be facilitated by the interaction of hLysRS with a tRNA-like element (TLE) first identified in the HIV-1 5"-untranslated region (5"-UTR) of the subtype B NL4-3 virus. pbs 64-67 lysyl-tRNA synthetase 1 Homo sapiens 138-144 28860303-6 2017 hLysRS bound to a 229-nt MAL RNA containing the PBS domain with high affinity (Kd = 47 nM), and to a 98-nt truncated construct with ~10-fold reduced affinity. pbs 48-51 lysyl-tRNA synthetase 1 Homo sapiens 0-6 28986376-6 2017 MS2 in phosphate-buffered saline (PBS) demonstrated approximately 5 times less adhesion force to glass (0.54 nN) than to PVC (2.87 nN) (P < 0.0001). pbs 34-37 MS2 Homo sapiens 0-3 28707305-6 2017 bFGF released from devices incubated in phosphate-buffered saline (PBS) enhanced the growth of fibroblasts, indicating bioactivity of bFGF after release. pbs 67-70 fibroblast growth factor 2 Rattus norvegicus 0-4 28707305-6 2017 bFGF released from devices incubated in phosphate-buffered saline (PBS) enhanced the growth of fibroblasts, indicating bioactivity of bFGF after release. pbs 67-70 fibroblast growth factor 2 Rattus norvegicus 134-138 28798033-11 2017 Conclusion:18F-NaF PET/CT and whole-body SPECT/CT resulted in a significant reduction of equivocal readings compared with pBS, which implies an improved diagnostic confidence. pbs 122-125 C-X-C motif chemokine ligand 8 Homo sapiens 15-18 28877986-5 2017 In the absence of import into the nucleus, Ssd1 fails to associate with PBs in the cytoplasm but rather is targeted to cytosolic insoluble protein deposits (IPODs). pbs 72-75 mRNA-binding translational repressor SSD1 Saccharomyces cerevisiae S288C 43-47 28513723-10 2017 However, only the PMAO-BHMT coating provided an effective protection against the dissolution of the UCNPs and long-term colloidal stability in PBS, and did not show cytotoxicity in EAhy926 endothelial cells. pbs 143-146 betaine--homocysteine S-methyltransferase Homo sapiens 23-27 29043827-8 2017 Set 2 DTT-treated RBCs were stored in pH 7.3 PBS. pbs 45-48 SET domain containing 2, histone lysine methyltransferase Homo sapiens 0-5 28650005-7 2017 ssDNA aptamer functionalized molybdenum disulfide (MoS2) for selective and specific capture of thrombin was demonstrated both in phosphate buffered saline (PBS) and human serum. pbs 156-159 coagulation factor II, thrombin Homo sapiens 95-103 29045428-5 2017 TPK2 deletion leads to a robust translational arrest, an increase in SGs/PBs aggregation and translational hypersensitivity to heat stress, whereas TPK3 deletion represses SGs/PBs formation, translational arrest and response for the analyzed mRNAs. pbs 73-76 cAMP-dependent protein kinase catalytic subunit TPK2 Saccharomyces cerevisiae S288C 0-4 29045428-5 2017 TPK2 deletion leads to a robust translational arrest, an increase in SGs/PBs aggregation and translational hypersensitivity to heat stress, whereas TPK3 deletion represses SGs/PBs formation, translational arrest and response for the analyzed mRNAs. pbs 176-179 cAMP-dependent protein kinase catalytic subunit TPK2 Saccharomyces cerevisiae S288C 0-4 29045428-5 2017 TPK2 deletion leads to a robust translational arrest, an increase in SGs/PBs aggregation and translational hypersensitivity to heat stress, whereas TPK3 deletion represses SGs/PBs formation, translational arrest and response for the analyzed mRNAs. pbs 176-179 cAMP-dependent protein kinase catalytic subunit TPK3 Saccharomyces cerevisiae S288C 148-152 28139016-8 2017 Collagen and cartilage degeneration were decreased by APS treatment, resulting in a significantly improved total joint score in APS-treated rats compared to those treated with the PBS control. pbs 180-183 SH2B adaptor protein 2 Rattus norvegicus 54-57 28139016-8 2017 Collagen and cartilage degeneration were decreased by APS treatment, resulting in a significantly improved total joint score in APS-treated rats compared to those treated with the PBS control. pbs 180-183 SH2B adaptor protein 2 Rattus norvegicus 128-131 28400013-5 2017 After three months and for all PBS aw levels tested, M120 and DK1 spores showed a ~1 decimal reduction in colony formation but this was not the case when kept in beef jerky suggesting a protective food matrix effect. pbs 31-34 immunoglobulin heavy diversity 5-12 Homo sapiens 62-65 28463531-4 2017 Reactome analysis demonstrated a significant enrichment of genes involved in HIF1alpha and HIF2alpha transcription factor network, metabolism and MYC related pathways in hypoxic compared with normoxic PBs. pbs 201-204 hypoxia inducible factor 1 subunit alpha Homo sapiens 77-86 28463531-4 2017 Reactome analysis demonstrated a significant enrichment of genes involved in HIF1alpha and HIF2alpha transcription factor network, metabolism and MYC related pathways in hypoxic compared with normoxic PBs. pbs 201-204 endothelial PAS domain protein 1 Homo sapiens 91-100 28463531-4 2017 Reactome analysis demonstrated a significant enrichment of genes involved in HIF1alpha and HIF2alpha transcription factor network, metabolism and MYC related pathways in hypoxic compared with normoxic PBs. pbs 201-204 MYC proto-oncogene, bHLH transcription factor Homo sapiens 146-149 28463531-7 2017 According to the role of hypoxia in supporting PBs generation through cell cycle induction, c-MYC activation and metabolism alteration, it could be involved in plasma cell tumorigenesis. pbs 47-50 MYC proto-oncogene, bHLH transcription factor Homo sapiens 92-97 28129516-14 2017 PRG4 production was elevated in the rhPRG4 group synovial fluid compared with the PBS group ( P = .033). pbs 82-85 proteoglycan 4 Homo sapiens 0-4 28406644-9 2017 In addition, whereas [2b]PF6 was photostable in PBS, [2a]PF6 quantitatively isomerized to [2b]PF6 upon light irradiation. pbs 48-51 sperm associated antigen 17 Homo sapiens 25-28 28423667-4 2017 The results demonstrated that PBS, when reacted with annexin V binding buffer, produced nano-sized vesicles even when there were no MVs in the sample. pbs 30-33 annexin A5 Homo sapiens 53-62 28423667-6 2017 Annexin V positive rate increased significantly when PBS was used as the buffer, compared to saline and water. pbs 53-56 annexin A5 Homo sapiens 0-9 27943400-5 2017 The injection of HMGB1 into the IMQ-treated skin further aggravated the psoriasis-like disease, enhanced the infiltration of CD3+ T cells, myeloperoxidase+ neutrophils and CD11c+ dendritic cells, increased the number of gammadelta T cells, and upregulated the mRNA expression of interleukin (IL)-6, tumor necrosis factor (TNF)-alpha, interferon (IFN)-gamma and IL-17 compared with the PBS injection. pbs 385-388 high mobility group box 1 Homo sapiens 17-22 28213255-3 2017 Cyclic voltammetric results reveal direct electron transfer of the immobilized GOx, indicated by two quasi-reversible redox peaks at a potential of 0.37V (vs. Ag/AgCl) in phosphate buffered solution (PBS) (0.10M, pH 7). pbs 200-203 hydroxyacid oxidase 1 Homo sapiens 79-82 28387583-3 2017 Here, we characterized the binding stoichiometry and sizes of soluble TNF-antagonist complexes for adalimumab, infliximab, and etanercept that were formed in human serum and in phosphate-buffered saline (PBS). pbs 204-207 tumor necrosis factor Homo sapiens 70-73 28387583-6 2017 The emergence of peaks with higher sedimentation coefficients than the adalimumab monomer as a function of added human serum albumin (HSA) concentration in PBS suggested weak reversible interactions between HSA and immunoglobulins. pbs 156-159 albumin Homo sapiens 119-132 27529414-6 2017 In addition, the max contact area and swing speed in the OCT/bFGF group were significantly recovered compared to the OCT/PBS and Defect groups at 8 weeks. pbs 121-124 fibroblast growth factor 2 Rattus norvegicus 61-65 27890571-5 2017 CTS/TPP NPs quickly aggregate in PBS (phosphate buffered saline) and DMEM (Dulbecco"s modified Eagle"s medium). pbs 33-36 transthyretin Homo sapiens 0-3 28244521-5 2017 At a current density of 10 mA cm-2, FeP NPs@NPC displays overpotentials of 130, 386 and 214 mV in 0.5 M H2SO4, 1.0 M phosphate buffer solution (PBS) and 1.0 M KOH, respectively. pbs 144-147 NPC intracellular cholesterol transporter 1 Homo sapiens 44-47 27836362-8 2017 RESULTS: Compared to controls, MS+PBS mice had shorter crypt lengths, fewer goblet cells per crypt, reduced glutathione peroxidase activity, increased expression of thiobarbituric acid reactive substances and inducible nitric oxide synthase mRNA, as well as increased IL-6, TNFalpha and myeloperoxidase. pbs 34-37 interleukin 6 Mus musculus 268-272 27836362-8 2017 RESULTS: Compared to controls, MS+PBS mice had shorter crypt lengths, fewer goblet cells per crypt, reduced glutathione peroxidase activity, increased expression of thiobarbituric acid reactive substances and inducible nitric oxide synthase mRNA, as well as increased IL-6, TNFalpha and myeloperoxidase. pbs 34-37 tumor necrosis factor Mus musculus 274-282 27836362-8 2017 RESULTS: Compared to controls, MS+PBS mice had shorter crypt lengths, fewer goblet cells per crypt, reduced glutathione peroxidase activity, increased expression of thiobarbituric acid reactive substances and inducible nitric oxide synthase mRNA, as well as increased IL-6, TNFalpha and myeloperoxidase. pbs 34-37 myeloperoxidase Mus musculus 287-302 27733488-21 2017 Fetuin-B ASO-treated females had 12.1 +- 3.1% of the liver Fetub mRNA level seen in PBS-treated females. pbs 84-87 fetuin beta Mus musculus 0-8 27733488-21 2017 Fetuin-B ASO-treated females had 12.1 +- 3.1% of the liver Fetub mRNA level seen in PBS-treated females. pbs 84-87 fetuin beta Mus musculus 59-64 26746670-10 2017 Partially silencing the expression of SOD3 using siRNA prior to LIF treatment counteracted the protective effect of LIF-alone PBS treatment. pbs 126-129 superoxide dismutase 3 Rattus norvegicus 38-42 26746670-10 2017 Partially silencing the expression of SOD3 using siRNA prior to LIF treatment counteracted the protective effect of LIF-alone PBS treatment. pbs 126-129 LIF, interleukin 6 family cytokine Rattus norvegicus 116-119 27560658-7 2016 After 28 d of injection, administration of only PBS into the site of muscle injury caused up-regulation in the levels of interleukins IL-1beta, IL-6, tumor necrosis factor alpha (TNF-alpha), transforming growth factor beta (TGF-beta1), interferon alpha (IFN-alpha) and down-regulate the level of IL-10 in muscular tissue comparing to the untreated control. pbs 48-51 interleukin 1 beta Rattus norvegicus 134-142 27894122-5 2017 RESULTS: In the Bcl-2-BMSCs group, the average times of erection, rate of erection, peak intra-cavernous pressure (ICP) and peak ICP/mean arterial pressure were higher than those in the null-BMSCs, BMSCs and PBS groups, but were lower than those in the normal control group. pbs 208-211 BCL2, apoptosis regulator Rattus norvegicus 16-21 28001241-2 2016 The authors conducted an in vitro evaluation of the amount of TGF-b1 released from dentin slices after treatment with 10% ethylenediaminetetraacetic acid (EDTA), 2.5% sodium hypochlorite (NaOCl) or phosphate-buffered saline (PBS), and the effect of this growth factor on stem cell migration from human exfoliated deciduous teeth (SHED). pbs 225-228 transforming growth factor beta 1 Homo sapiens 62-68 28003971-14 2016 Compared with PBS-injected group, the extended IOP elevation was associated with the degeneration of optic nerve, the reduction of RGC axons (47.16%, P<0.05) and the increased GFAP expression in the retina (4.74+-1.10 vs 1.00+-0.46, P<0.05). pbs 14-17 glial fibrillary acidic protein Oryctolagus cuniculus 179-183 27560658-7 2016 After 28 d of injection, administration of only PBS into the site of muscle injury caused up-regulation in the levels of interleukins IL-1beta, IL-6, tumor necrosis factor alpha (TNF-alpha), transforming growth factor beta (TGF-beta1), interferon alpha (IFN-alpha) and down-regulate the level of IL-10 in muscular tissue comparing to the untreated control. pbs 48-51 interleukin 6 Rattus norvegicus 144-148 27560658-7 2016 After 28 d of injection, administration of only PBS into the site of muscle injury caused up-regulation in the levels of interleukins IL-1beta, IL-6, tumor necrosis factor alpha (TNF-alpha), transforming growth factor beta (TGF-beta1), interferon alpha (IFN-alpha) and down-regulate the level of IL-10 in muscular tissue comparing to the untreated control. pbs 48-51 tumor necrosis factor Rattus norvegicus 150-177 27560658-7 2016 After 28 d of injection, administration of only PBS into the site of muscle injury caused up-regulation in the levels of interleukins IL-1beta, IL-6, tumor necrosis factor alpha (TNF-alpha), transforming growth factor beta (TGF-beta1), interferon alpha (IFN-alpha) and down-regulate the level of IL-10 in muscular tissue comparing to the untreated control. pbs 48-51 tumor necrosis factor Rattus norvegicus 179-188 27560658-7 2016 After 28 d of injection, administration of only PBS into the site of muscle injury caused up-regulation in the levels of interleukins IL-1beta, IL-6, tumor necrosis factor alpha (TNF-alpha), transforming growth factor beta (TGF-beta1), interferon alpha (IFN-alpha) and down-regulate the level of IL-10 in muscular tissue comparing to the untreated control. pbs 48-51 transforming growth factor, beta 1 Rattus norvegicus 224-233 27560658-7 2016 After 28 d of injection, administration of only PBS into the site of muscle injury caused up-regulation in the levels of interleukins IL-1beta, IL-6, tumor necrosis factor alpha (TNF-alpha), transforming growth factor beta (TGF-beta1), interferon alpha (IFN-alpha) and down-regulate the level of IL-10 in muscular tissue comparing to the untreated control. pbs 48-51 interleukin 10 Rattus norvegicus 296-301 27560658-8 2016 Bone marrow MSCs + PBS injected at the site of muscle injury significantly down-regulate the inflammatory cytokines levels IL-1beta and IL-6 and TNF-alpha, TGF-beta1 and IFN-alpha and up-regulate the level of IL-10. pbs 19-22 interleukin 1 beta Rattus norvegicus 123-131 27560658-8 2016 Bone marrow MSCs + PBS injected at the site of muscle injury significantly down-regulate the inflammatory cytokines levels IL-1beta and IL-6 and TNF-alpha, TGF-beta1 and IFN-alpha and up-regulate the level of IL-10. pbs 19-22 interleukin 6 Rattus norvegicus 136-140 27560658-8 2016 Bone marrow MSCs + PBS injected at the site of muscle injury significantly down-regulate the inflammatory cytokines levels IL-1beta and IL-6 and TNF-alpha, TGF-beta1 and IFN-alpha and up-regulate the level of IL-10. pbs 19-22 tumor necrosis factor Rattus norvegicus 145-154 27560658-8 2016 Bone marrow MSCs + PBS injected at the site of muscle injury significantly down-regulate the inflammatory cytokines levels IL-1beta and IL-6 and TNF-alpha, TGF-beta1 and IFN-alpha and up-regulate the level of IL-10. pbs 19-22 transforming growth factor, beta 1 Rattus norvegicus 156-165 27560658-8 2016 Bone marrow MSCs + PBS injected at the site of muscle injury significantly down-regulate the inflammatory cytokines levels IL-1beta and IL-6 and TNF-alpha, TGF-beta1 and IFN-alpha and up-regulate the level of IL-10. pbs 19-22 interleukin 10 Rattus norvegicus 209-214 27560658-11 2016 Microvasculature of skeletal muscle was decreased as demonstrated by immunostaining technique for CD34 in PBS group from untreated control. pbs 106-109 CD34 molecule Rattus norvegicus 98-102 27733621-4 2016 We show that one of these interactors, matrin-3 (matr3), localizes to mRNA processing bodies (PBs), where we have previously shown a nesprin-1 isoform to localize. pbs 94-97 matrin 3 Homo sapiens 39-54 27852925-4 2016 Recently, a tRNA-like element (TLE) within the HIV-1 gRNA was shown to mimic the global tRNA fold and bind competitively to hLysRS, suggesting a mechanism of tRNA targeting to the primer binding site (PBS) and release from the synthetase. pbs 201-204 lysyl-tRNA synthetase 1 Homo sapiens 124-130 27805598-9 2016 Furthermore, in order to imitate the human physiology, mechanical tests were also performed in phosphate buffered saline (PBS) solution at 37 C. The method herein presented provides a high control of porosity, pore size distribution and mechanical performance, thus offering the possibility to fabricate three-layered scaffolds with tailored properties by following a simple and eco-friendly route. pbs 122-125 ciliogenesis associated kinase 1 Homo sapiens 380-383 27733621-4 2016 We show that one of these interactors, matrin-3 (matr3), localizes to mRNA processing bodies (PBs), where we have previously shown a nesprin-1 isoform to localize. pbs 94-97 spectrin repeat containing nuclear envelope protein 1 Homo sapiens 133-142 27140104-4 2016 An ultrashort (~8.13 mum long) PBS is designed based on a silicon-on-insulator nanowire with a loading refractive index of 2.0 and a gap width of 200 nm. pbs 32-35 latexin Homo sapiens 22-25 27181906-8 2016 RESULTS: PCR examination revealed that the lipopolysaccharide-injected mice showed a significant up-regulation of macrophage migration inhibitory factor in both the middle ear and inner ear as compared with the PBS-injected control mice. pbs 211-214 macrophage migration inhibitory factor (glycosylation-inhibiting factor) Mus musculus 114-152 26912505-5 2016 Children and adolescents supported with PBS showed improvement in challenging behaviours and social and communication skills, at a total weekly cost of GBP 1909 (and GBP 1951 including carer-related costs). pbs 40-43 transmembrane protein 132A Homo sapiens 152-155 26912505-5 2016 Children and adolescents supported with PBS showed improvement in challenging behaviours and social and communication skills, at a total weekly cost of GBP 1909 (and GBP 1951 including carer-related costs). pbs 40-43 transmembrane protein 132A Homo sapiens 166-169 27588134-5 2016 The correlation of oxidative stress with Abeta levels was lower in the hAMMSCs-injected group than in the phosphate-buffered saline (PBS)-injected group, as indicated by the increased level of antioxidative enzymes and the decreased level of lipid peroxidation product. pbs 133-136 amyloid beta precursor protein Homo sapiens 41-46 27578149-1 2016 BACKGROUND: Eukaryotic translation initiation factor 4E (eIF4E) plays a pivotal role in the control of cap-dependent translation initiation, modulates the fate of specific mRNAs, occurs in processing bodies (PBs) and is required for formation of stress granules (SGs). pbs 208-211 eukaryotic translation initiation factor 4E Homo sapiens 12-55 27578149-1 2016 BACKGROUND: Eukaryotic translation initiation factor 4E (eIF4E) plays a pivotal role in the control of cap-dependent translation initiation, modulates the fate of specific mRNAs, occurs in processing bodies (PBs) and is required for formation of stress granules (SGs). pbs 208-211 eukaryotic translation initiation factor 4E Homo sapiens 57-62 27247266-7 2016 Depletion of PRMT5, the primary protein arginine methyltransferase responsible for symmetric arginine dimethylation, including Lsm4, resulted in loss of PBs. pbs 153-156 protein arginine methyltransferase 5 Homo sapiens 13-18 27247266-7 2016 Depletion of PRMT5, the primary protein arginine methyltransferase responsible for symmetric arginine dimethylation, including Lsm4, resulted in loss of PBs. pbs 153-156 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated Homo sapiens 127-131 27179870-6 2016 Both, PBS and LPS infusions induced subclinical endometritis, which was accompanied by increased endometrial mRNA abundance of proinflammatory cytokines IL1beta, IL8, and tumor necrosis factor alpha. pbs 6-9 interleukin 1 beta Bos taurus 153-160 27179870-6 2016 Both, PBS and LPS infusions induced subclinical endometritis, which was accompanied by increased endometrial mRNA abundance of proinflammatory cytokines IL1beta, IL8, and tumor necrosis factor alpha. pbs 6-9 C-X-C motif chemokine ligand 8 Bos taurus 162-165 27179870-6 2016 Both, PBS and LPS infusions induced subclinical endometritis, which was accompanied by increased endometrial mRNA abundance of proinflammatory cytokines IL1beta, IL8, and tumor necrosis factor alpha. pbs 6-9 tumor necrosis factor Bos taurus 171-198 27107641-0 2016 DHX9/RHA Binding to the PBS-Segment of the Genomic RNA during HIV-1 Assembly Bolsters Virion Infectivity. pbs 24-27 DExH-box helicase 9 Homo sapiens 0-4 27107641-0 2016 DHX9/RHA Binding to the PBS-Segment of the Genomic RNA during HIV-1 Assembly Bolsters Virion Infectivity. pbs 24-27 DExH-box helicase 9 Homo sapiens 5-8 27107641-6 2016 The structure of the large molecular mass complex was dependent on RHA binding to a double-stranded region of the primer binding site (PBS)-segment of the 5"-UTR. pbs 135-138 DExH-box helicase 9 Homo sapiens 67-70 27107641-9 2016 The support of progeny virion infectivity by RHA is attributable to structure-dependent binding at the PBS-segment of the HIV-1 5"-UTR during virus assembly. pbs 103-106 DExH-box helicase 9 Homo sapiens 45-48 27259948-9 2016 The expression of Iba1 and CD68 in the optic nerve was lower in the etanercept-treated groups than in the PBS-treated groups. pbs 106-109 allograft inflammatory factor 1 Rattus norvegicus 18-22 27259948-9 2016 The expression of Iba1 and CD68 in the optic nerve was lower in the etanercept-treated groups than in the PBS-treated groups. pbs 106-109 Cd68 molecule Rattus norvegicus 27-31 27259948-10 2016 Immunohistochemical staining using rabbit anti-Iba1 antibody showed that the amount of microglia at the optic nerve head was noticeably lower in the etanercept-treated groups than in the PBS-treated groups. pbs 187-190 allograft inflammatory factor 1 Rattus norvegicus 47-51 27082164-10 2016 Furthermore, in the Per2 overexpression group, MTA-1 protein expression was significantly reduced when compared with the phosphate-buffered saline (PBS) control and empty plasmid groups, while nm23-H1 protein expression was significantly higher when compared with those two groups. pbs 148-151 period circadian clock 2 Mus musculus 20-24 27082164-11 2016 The expression levels of PI3K and PKB kinase, which are marker proteins of the autophagy associated signaling pathway PI3K/PKB, were significantly downregulated, when compared with the PBS control and empty plasmid groups (P<0.001). pbs 185-188 thymoma viral proto-oncogene 1 Mus musculus 34-37 27242885-2 2016 PBs can also be induced to form in leaves when foreign proteins are produced at high levels in the endoplasmic reticulum (ER) and when fused to one of three tags: Zera , elastin-like polypeptides (ELP), or hydrophobin-I (HFBI). pbs 0-3 nuclear receptor subfamily 5 group A member 1 Homo sapiens 170-195 27242885-2 2016 PBs can also be induced to form in leaves when foreign proteins are produced at high levels in the endoplasmic reticulum (ER) and when fused to one of three tags: Zera , elastin-like polypeptides (ELP), or hydrophobin-I (HFBI). pbs 0-3 nuclear receptor subfamily 5 group A member 1 Homo sapiens 197-200 27084642-13 2016 Pencil beam scanning dosimetric gains in the bowel (V15, V20) over VMAT suggest that using PBS to treat rectal cancer may reduce radiation treatment-related toxicity. pbs 91-94 immunoglobulin lambda variable 2-18 Homo sapiens 52-55 27582587-10 2016 RESULTS: The PEDF protein level in the group with NSC-based administration of PEDF increased compared with that in the groups with injections of PEDF and PBS (P<0.05). pbs 154-157 serpin family F member 1 Rattus norvegicus 13-17 27176485-13 2016 Both HA and PBS induced acute tendon injury and inflammation, sequential histopathological changes, ED1+ and ED2+ macrophage accumulation, IL-1beta expression, and neovascularization until post-injection day 42.HA induced more-severe injury than did PBS. pbs 12-15 interleukin 1 beta Rattus norvegicus 139-147 26801818-4 2016 First, the molarities of phosphate buffer saline (PBS) and concentrations of KCl as ionic strength adjuster were optimized to maximize the GOx glucose-based enzymatic reactions in a beaker for signal amplification measured by change in the voltage shift with an EIS device (using 20 mul of solution) and validated with a commercial pH meter (using 3 ml of solution). pbs 50-53 hydroxyacid oxidase 1 Homo sapiens 139-142 26801818-6 2016 These optimized buffer conditions were further verified for GOx immobilized on silicon chips, and similar trends with decreased PBS molarity were obtained; however, the voltage shift values obtained on chip reaction were lower as compared to the reactions occurring in the beaker. pbs 128-131 hydroxyacid oxidase 1 Homo sapiens 60-63 26987291-7 2016 In C3H mice bearing synergic SCCVII tumors, the growth of tumors injected with the supernatant of RH2-infected cells was less than that of tumors injected with phosphate-buffered saline (PBS). pbs 187-190 Rh associated glycoprotein Homo sapiens 98-101 26694855-7 2016 CD spectroscopy, FTIR, and transmission electron microscopy reveal that pufferfish IAPP forms amyloid and does so more rapidly than human IAPP in tris buffer at pH 7.4, but does so more slowly in phosphate buffered saline (PBS) at pH 7.4. pbs 223-226 islet amyloid polypeptide Homo sapiens 83-87 26671457-7 2016 Further, using species-specific PRDM9 sequences to predict potential binding sites (PBS), we show higher predicted PRDM9 binding in recombination hotspots as compared to matched cold spot regions in multiple great ape species, including at least one chimpanzee subspecies. pbs 84-87 PRDM9 Pan troglodytes 32-37 26671457-7 2016 Further, using species-specific PRDM9 sequences to predict potential binding sites (PBS), we show higher predicted PRDM9 binding in recombination hotspots as compared to matched cold spot regions in multiple great ape species, including at least one chimpanzee subspecies. pbs 84-87 PRDM9 Pan troglodytes 115-120 26978070-6 2016 The protein-protein interactions apparently take place in processing bodies (PBs) and stress granules (SGs), because AtTZF5, MARD1 and RD21A could interact and co-localize with each other and they all can co-localize with the same PB and SG markers in plant cells. pbs 77-80 Zinc finger C-x8-C-x5-C-x3-H type family protein Arabidopsis thaliana 117-123 26978070-6 2016 The protein-protein interactions apparently take place in processing bodies (PBs) and stress granules (SGs), because AtTZF5, MARD1 and RD21A could interact and co-localize with each other and they all can co-localize with the same PB and SG markers in plant cells. pbs 77-80 mediator of aba-regulated dormancy protein (DUF581) Arabidopsis thaliana 125-130 26978070-6 2016 The protein-protein interactions apparently take place in processing bodies (PBs) and stress granules (SGs), because AtTZF5, MARD1 and RD21A could interact and co-localize with each other and they all can co-localize with the same PB and SG markers in plant cells. pbs 77-80 Granulin repeat cysteine protease family protein Arabidopsis thaliana 135-140 26909090-7 2016 While the zein portion used to induce protein body formation was only weakly immunogenic, our results indicate that zein-induced PBs are promising production and delivery vehicles for subunit vaccines. pbs 129-132 zein Zea mays 116-120 26459017-14 2015 FGF10 significantly induced the mRNA expression of Muc1 in the corneal epithelial cells, compared with the normal control group, and induced higher mRNA expression levels of Muc1 in the Cj-ECs, compared with the PBS control group. pbs 212-215 fibroblast growth factor 10 Oryctolagus cuniculus 0-5 26448173-9 2015 In the anti-IL-6R group, the expression levels of matrix metalloproteinase-13, monocyte chemotactic protein-1, and C-C motif ligand-22 were downregulated compared with those in the PBS group. pbs 181-184 interleukin 6 receptor, alpha Mus musculus 12-17 26491048-6 2016 CUGBP1 overexpression in Caco-2 cells inhibited E-cadherin translation by increasing the recruitment of E-cadherin mRNA to processing bodies (PBs), thus resulting in an increase in paracellular permeability. pbs 142-145 CUGBP Elav-like family member 1 Homo sapiens 0-6 26491048-7 2016 Overexpression of HuR exhibited an opposite effect on E-cadherin expression by preventing the translocation of E-cadherin mRNA to PBs and therefore prevented CUGBP1-induced repression of E-cadherin expression. pbs 130-133 ELAV like RNA binding protein 1 Homo sapiens 18-21 26491048-7 2016 Overexpression of HuR exhibited an opposite effect on E-cadherin expression by preventing the translocation of E-cadherin mRNA to PBs and therefore prevented CUGBP1-induced repression of E-cadherin expression. pbs 130-133 cadherin 1 Homo sapiens 54-64 26491048-9 2016 These findings indicate that CUGBP1 and HuR negate each other"s effects in regulating E-cadherin translation by altering the recruitment of E-cadherin mRNA to PBs and play an important role in the regulation of intestinal barrier integrity under various pathophysiological conditions. pbs 159-162 CUGBP Elav-like family member 1 Homo sapiens 29-35 26491048-9 2016 These findings indicate that CUGBP1 and HuR negate each other"s effects in regulating E-cadherin translation by altering the recruitment of E-cadherin mRNA to PBs and play an important role in the regulation of intestinal barrier integrity under various pathophysiological conditions. pbs 159-162 ELAV like RNA binding protein 1 Homo sapiens 40-43 26491048-9 2016 These findings indicate that CUGBP1 and HuR negate each other"s effects in regulating E-cadherin translation by altering the recruitment of E-cadherin mRNA to PBs and play an important role in the regulation of intestinal barrier integrity under various pathophysiological conditions. pbs 159-162 cadherin 1 Homo sapiens 86-96 26491048-9 2016 These findings indicate that CUGBP1 and HuR negate each other"s effects in regulating E-cadherin translation by altering the recruitment of E-cadherin mRNA to PBs and play an important role in the regulation of intestinal barrier integrity under various pathophysiological conditions. pbs 159-162 cadherin 1 Homo sapiens 140-150 26870205-6 2016 Furthermore, the apoptosis rate and the mRNA and protein expression levels of hIFN-lambda1 were higher in pAd-hIFN-lambda1-transfected cells, compared with the pAd-LacZ and PBS control groups. pbs 173-176 interferon lambda 1 Homo sapiens 78-90 26099467-5 2015 The release profile of Fab1, measured in phosphate-buffered saline (PBS), showed a lag phase followed by sustained-release phase for close to 80 days. pbs 68-71 phosphoinositide kinase, FYVE-type zinc finger containing Homo sapiens 23-27 25923925-8 2015 The bovine serum albumin (BSA) binding behaviours of the studied quaternized ionic zinc(ii) phthalocyanines were also described in PBS solutions. pbs 131-134 albumin Homo sapiens 11-24 26417948-2 2015 ZFP809 is known to inhibit the expression of transduced genes driven by Moloney murine leukemia virus (MoMLV)-typed retroviral vectors by binding to the primer binding site (PBS) located downstream of the MLV-long terminal repeat (LTR) of the vectors and recruiting protein complexes that introduce epigenetic silencing marks such as histone modifications and DNA methylation at the MLV-LTR. pbs 174-177 zinc finger protein 809 Mus musculus 0-6 26417948-4 2015 In this study, we assessed subcellular localization, gene silencing ability, and binding ability to the PBS of a series of truncated and mutated ZFP809 proteins. pbs 104-107 zinc finger protein 809 Mus musculus 145-151 25950938-2 2015 In this work we fabricated immunosensors by depositing layer-by-layer (LbL) films made with an antigenic peptide (p17-1) sequence (H2N-LSGGELDRWEKIRLRPGG-OH) and lignin on interdigitated gold electrodes, which could detect anti-p17 (HIV, human immune deficiency virus) antibodies (Ab) in phosphate buffered solutions (PBS). pbs 318-321 family with sequence similarity 72 member B Homo sapiens 114-117 26166725-9 2015 Collectively, these results demonstrate that intranasal administration of GDNF in liposomes or PBS achieves significant increases in GDNF in target brain areas, supporting use of intranasal administration as a non-invasive means of delivering GDNF to the brain to protect dopamine neurons and arrest disease progression in PD. pbs 95-98 glial cell derived neurotrophic factor Rattus norvegicus 133-137 26166725-9 2015 Collectively, these results demonstrate that intranasal administration of GDNF in liposomes or PBS achieves significant increases in GDNF in target brain areas, supporting use of intranasal administration as a non-invasive means of delivering GDNF to the brain to protect dopamine neurons and arrest disease progression in PD. pbs 95-98 glial cell derived neurotrophic factor Rattus norvegicus 133-137 25640969-9 2015 We propose to use this property of PBs as a tool to increase the accumulation levels of erythropoietin and human interleukin-10 by co-expression with PB-inducing proteins. pbs 35-38 erythropoietin Homo sapiens 88-102 25640969-9 2015 We propose to use this property of PBs as a tool to increase the accumulation levels of erythropoietin and human interleukin-10 by co-expression with PB-inducing proteins. pbs 35-38 interleukin 10 Homo sapiens 113-127 26255110-8 2015 In Abeta1-42-injected rat brain, CXCR2 and IL-8 showed time-dependent increases in expression, concomitant with enhanced gliosis, relative to controls phosphate-buffered saline (PBS) or reverse peptide Abeta42-1 injection. pbs 178-181 C-X-C motif chemokine receptor 2 Rattus norvegicus 33-38 26178579-5 2015 Results found that compared to the phosphate-buffered saline (PBS)-treated or the negative control (NC) siRNA-treated mice tumour xenograft weight and volume were significantly decreased in the NF-kappaB p65 siRNA-treated mice. pbs 62-65 RELA proto-oncogene, NF-kB subunit Homo sapiens 194-207 26178579-7 2015 Compared to the PBS or the NC mice, levels of Bcl-2 mRNA and protein in tumour xenografts were significantly downregulated in p65 siRNA-treated mice. pbs 16-19 B cell leukemia/lymphoma 2 Mus musculus 46-51 26178579-7 2015 Compared to the PBS or the NC mice, levels of Bcl-2 mRNA and protein in tumour xenografts were significantly downregulated in p65 siRNA-treated mice. pbs 16-19 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 126-129 26120273-10 2015 The production of HO-1 protein in the 100 muM fasudil group was 1.52+-0.34 times more than in the PBS group (n=5 sample, p<0.05). pbs 98-101 heme oxygenase 1 Mus musculus 18-22 32262789-4 2015 After the addition of GSH (2 mM), DATS-MSN (100 mug mL-1) steadily releases moderate amounts of H2S (peaking at the 4th hour, ~60 muM) in phosphate buffer solution (PBS). pbs 165-168 L1 cell adhesion molecule Mus musculus 52-56 25142552-10 2015 Lung histology showed a significant reduction in cellular infiltrate in mice treated with P-2-2 and P-3-2 compared to PBS. pbs 118-121 dynein cytoplasmic 1 heavy chain 1 Mus musculus 90-105 25601926-7 2015 In iGB culture, JNK inhibitor SP600125 augmented the differentiation of C57BL/6 B1a cells into PBs. pbs 95-98 mitogen-activated protein kinase 8 Mus musculus 16-19 25601926-8 2015 Furthermore, B1a cells from G5PR transgenic mice markedly differentiated into IgM and IgG autoantibody-secreting PBs. pbs 113-116 protein phosphatase 2, regulatory subunit B'', gamma Mus musculus 28-32 25601926-9 2015 In conclusion, JNK regulation is critical to suppress autoantibody-secreting PBs from peritoneal B1a cells. pbs 77-80 mitogen-activated protein kinase 8 Mus musculus 15-18 25385769-11 2015 Consistent with this, we found that viral recovery induced increased PB formation and that a decapping mutant (DCP2) showed increased VIGS and virus RNA accumulation, indicating an important role for PBs in eliminating viral RNA. pbs 200-203 decapping mRNA 2 Homo sapiens 111-115 25243540-1 2015 PURPOSE: To compare the occurrence of several central sulcus variants and to assess the reproducibility of a sulcal pattern named the power button sign (PBS) in patients with type 2 focal cortical dysplasia (FCD2) and healthy control subjects. pbs 153-156 FECD3 Homo sapiens 208-212 25243540-7 2015 The PBS was found in 23 (62%) of 37 total patients with FCD2, in six (46%) of 13 with negative MR imaging findings, and in only one control subject. pbs 4-7 FECD3 Homo sapiens 56-60 25243540-10 2015 CONCLUSION: Given its excellent reproducibility and specificity, the PBS, when present, could become a useful qualitative diagnostic MR criterion of FCD2 in the central region. pbs 69-72 FECD3 Homo sapiens 149-153 24862572-3 2014 Here, we characterize p50(Nesp1), a 50-kD isoform that localizes to processing bodies (PBs), where it acts as a microtubule-associated protein capable of linking mRNP complexes to microtubules. pbs 87-90 nuclear factor kappa B subunit 1 Homo sapiens 22-25 26554246-6 2015 The assay sensitivity was determined by measuring the quenched fluorescence intensity of AKR1B10 at 0.5, 1, 2, 5, or 10 ng/mL in phosphate-buffered solution (PBS) or 0.25%, 0.5%, 1.0%, 2.0%, or 5% human serum diluted in PBS. pbs 158-161 aldo-keto reductase family 1 member B10 Homo sapiens 89-96 24880451-4 2015 RESULTS: standards curves generated with the use of phosphate-buffered saline (PBS) demonstrated best adjustment for cytokines IL-1ss, IL-6 and TNF- alpha levels, when using Tris-HCl (p<0.05). pbs 79-82 interleukin 1 beta Homo sapiens 127-131 24880451-4 2015 RESULTS: standards curves generated with the use of phosphate-buffered saline (PBS) demonstrated best adjustment for cytokines IL-1ss, IL-6 and TNF- alpha levels, when using Tris-HCl (p<0.05). pbs 79-82 interleukin 6 Homo sapiens 135-139 24880451-4 2015 RESULTS: standards curves generated with the use of phosphate-buffered saline (PBS) demonstrated best adjustment for cytokines IL-1ss, IL-6 and TNF- alpha levels, when using Tris-HCl (p<0.05). pbs 79-82 tumor necrosis factor Homo sapiens 144-154 24967754-4 2014 The immobilized CAT shows a couple of reversible and well-defined cyclic voltammetry peaks with a formal potential (E(0)) of -0.471 V (vs. Ag/AgCl) in a pH 6.5 phosphate buffer solution (PBS). pbs 187-190 catalase Homo sapiens 16-19 25234602-10 2014 Confocal immunofluorescence demonstrated that MSCs survive and are associated with expression of connexin-43 (Cx43) for either PBS (control), 1%, or 2% alginate. pbs 127-130 gap junction protein alpha 1 Sus scrofa 97-108 25234602-10 2014 Confocal immunofluorescence demonstrated that MSCs survive and are associated with expression of connexin-43 (Cx43) for either PBS (control), 1%, or 2% alginate. pbs 127-130 gap junction protein alpha 1 Sus scrofa 110-114 24879591-5 2014 A detail EIS study was conducted on the bioelectrode towards the quantitative detection of the target Ag-CRP in phosphate-buffered saline (PBS). pbs 139-142 C-reactive protein Homo sapiens 105-108 24879591-7 2014 The bioelectrode exhibited a linear response of CRP detection in the range of 10 ng mL(-1) to 10 mug mL(-1) with a sensitivity of 92.86 Omegacm(2) per decade CRP in pH 7.4 PBS. pbs 172-175 C-reactive protein Homo sapiens 48-51 24879591-7 2014 The bioelectrode exhibited a linear response of CRP detection in the range of 10 ng mL(-1) to 10 mug mL(-1) with a sensitivity of 92.86 Omegacm(2) per decade CRP in pH 7.4 PBS. pbs 172-175 C-reactive protein Homo sapiens 158-161 24845869-7 2014 Both intranasal GDNF treatments induced a neurotrophic effect in the SN insofar as the number of tyrosine hydroxylase (TH)-positive neurons was significantly higher than in controls given intranasal PBS liposomes. pbs 199-202 glial cell derived neurotrophic factor Rattus norvegicus 16-20 24845869-9 2014 Most importantly, intranasal GDNF provided significant neuroprotective efficacy indicated by greater TH immunostaining density in the lesioned versus intact SN of rats given single 50-mug doses of GDNF in PBS, or 150-mug doses of liposomal GDNF, compared to lesioned rats given PBS liposomes. pbs 205-208 glial cell derived neurotrophic factor Rattus norvegicus 29-33 24845869-9 2014 Most importantly, intranasal GDNF provided significant neuroprotective efficacy indicated by greater TH immunostaining density in the lesioned versus intact SN of rats given single 50-mug doses of GDNF in PBS, or 150-mug doses of liposomal GDNF, compared to lesioned rats given PBS liposomes. pbs 278-281 glial cell derived neurotrophic factor Rattus norvegicus 29-33 25131477-8 2014 The concentrations in PBS/ox-LDL taken as repeated measurements, and adjusted for age and gender, the repeated general linear models showed: IL-10 was significantly lower for those overweight (BMI >= 26 kg/m(2)) than for those normal weight (P = 0.007), and IL-6/IL-10 was significantly higher in those overweight (P = 0.003). pbs 22-25 interleukin 10 Homo sapiens 141-146 25333196-5 2015 The majority of the inflammatory cells present in the corneas of the phosphate-buffered saline (PBS)-treated mice were neutrophils that expressed matrix metalloproteinase (MMP)-9. pbs 96-99 matrix metallopeptidase 9 Mus musculus 146-178 25463133-8 2014 The MPO/PON1 ratio amount was significantly higher in HSP65-immunized group than in normal or PBS-immunized group. pbs 94-97 myeloperoxidase Mus musculus 4-7 25463133-8 2014 The MPO/PON1 ratio amount was significantly higher in HSP65-immunized group than in normal or PBS-immunized group. pbs 94-97 paraoxonase 1 Mus musculus 8-12 25463133-9 2014 In addition, compared with normal or PBS-immunized group, cholesterol efflux rate and the expression of regulating proteins were markedly decreased in HSP65-immunized group. pbs 37-40 heat shock protein 1 (chaperonin) Mus musculus 151-156 25463133-10 2014 The mice immunized with HSP65 developed significantly larger aorta atherosclerotic plaques when compared with PBS-treated littermates. pbs 110-113 heat shock protein 1 (chaperonin) Mus musculus 24-29 25260727-6 2014 On day 5, dentin sialophosphoprotein and nestin were first recovered in the 3Mix group, whereas expression levels for alkaline phosphatase, osteopontin, and osteocalcin increased in the PBS group. pbs 186-189 secreted phosphoprotein 1 Mus musculus 140-151 25260727-6 2014 On day 5, dentin sialophosphoprotein and nestin were first recovered in the 3Mix group, whereas expression levels for alkaline phosphatase, osteopontin, and osteocalcin increased in the PBS group. pbs 186-189 bone gamma-carboxyglutamate protein 2 Mus musculus 157-168 24789780-3 2014 The nucleic acid (NA) chaperone function of the nucleocapsid (NC) domain of HIV-1 Gag is responsible for annealing tRNA(Lys3) to the genomic RNA (gRNA) primer binding site (PBS). pbs 173-176 Pr76 polyprotein precursor Rous sarcoma virus 82-85 24789780-10 2014 Importance: Mounting evidence suggests that the Gag polyprotein is responsible for annealing primer tRNAs to the PBS to initiate reverse transcription in retroviruses, but only HIV-1 Gag chaperone activity has been demonstrated in vitro. pbs 113-116 Pr55(Gag) Human immunodeficiency virus 1 48-51 25028550-2 2014 This study showed that when coated on tissue culture polystyrene, lubricin, a nanostructured mucinous glycoprotein found in the synovial fluid of joints, decreased fibroblast density for up to 2 days of culture compared to controls treated with phosphate buffered saline (PBS). pbs 272-275 proteoglycan 4 Bos taurus 66-74 24837681-8 2014 After Shh-BMSCs treatment of SCI via the subarachnoid, we detected significantly greater damage recovery compared with that seen in rats treated with phosphate-buffered saline (PBS) and BMSCs. pbs 177-180 sonic hedgehog signaling molecule Rattus norvegicus 6-9 24862572-3 2014 Here, we characterize p50(Nesp1), a 50-kD isoform that localizes to processing bodies (PBs), where it acts as a microtubule-associated protein capable of linking mRNP complexes to microtubules. pbs 87-90 spectrin repeat containing nuclear envelope protein 1 Homo sapiens 26-31 24634448-8 2014 RESULTS: Treatment with LR-PRP resulted in significantly greater synoviocyte death (4.9% +- 3.1%) compared with LP-PRP (0.72% +- 0.70%; P = .035), phosphate-buffered saline (PBS) (0.39% +- 0.27%; P = .018), and PPP (0.26% +- 0.30%; P = .013). pbs 174-177 complement component 4 binding protein alpha Homo sapiens 27-30 24524272-3 2014 The release of insulin from nanoparticles was studied in vitro in phosphate buffer solution (PBS) pH 7.4. pbs 93-96 insulin Oryctolagus cuniculus 15-22 24216203-5 2013 The laminated PBS consists of a PIM sensing disc (2mm in diameter) attached to the centre of a circular hydrophilic zone (7 mm in diameter) pretreated with 0.01 M HCl. pbs 14-17 Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens 32-35 24068615-3 2014 We recently demonstrated that laforin is a phosphatase of muscle glycogen synthase (GS1) in PBs, and that laforin recruits malin, together reducing PBs. pbs 92-95 EPM2A glucan phosphatase, laforin Homo sapiens 30-37 24068615-3 2014 We recently demonstrated that laforin is a phosphatase of muscle glycogen synthase (GS1) in PBs, and that laforin recruits malin, together reducing PBs. pbs 92-95 pseudouridine 5'-phosphatase Homo sapiens 84-87 24068615-3 2014 We recently demonstrated that laforin is a phosphatase of muscle glycogen synthase (GS1) in PBs, and that laforin recruits malin, together reducing PBs. pbs 148-151 EPM2A glucan phosphatase, laforin Homo sapiens 106-113 24068615-3 2014 We recently demonstrated that laforin is a phosphatase of muscle glycogen synthase (GS1) in PBs, and that laforin recruits malin, together reducing PBs. pbs 148-151 NHL repeat containing E3 ubiquitin protein ligase 1 Homo sapiens 123-128 24068615-5 2014 Once GS1-synthesized polyglucosan accumulates into PBs, laforin recruits malin to the PBs where laforin dephosphorylates, and malin degrades the GS1 in concert with GPBB and AGL1, resulting in a breakdown of polyglucosan. pbs 51-54 pseudouridine 5'-phosphatase Homo sapiens 5-8 24068615-5 2014 Once GS1-synthesized polyglucosan accumulates into PBs, laforin recruits malin to the PBs where laforin dephosphorylates, and malin degrades the GS1 in concert with GPBB and AGL1, resulting in a breakdown of polyglucosan. pbs 86-89 pseudouridine 5'-phosphatase Homo sapiens 5-8 24068615-5 2014 Once GS1-synthesized polyglucosan accumulates into PBs, laforin recruits malin to the PBs where laforin dephosphorylates, and malin degrades the GS1 in concert with GPBB and AGL1, resulting in a breakdown of polyglucosan. pbs 86-89 EPM2A glucan phosphatase, laforin Homo sapiens 56-63 24068615-5 2014 Once GS1-synthesized polyglucosan accumulates into PBs, laforin recruits malin to the PBs where laforin dephosphorylates, and malin degrades the GS1 in concert with GPBB and AGL1, resulting in a breakdown of polyglucosan. pbs 86-89 NHL repeat containing E3 ubiquitin protein ligase 1 Homo sapiens 73-78 24068615-5 2014 Once GS1-synthesized polyglucosan accumulates into PBs, laforin recruits malin to the PBs where laforin dephosphorylates, and malin degrades the GS1 in concert with GPBB and AGL1, resulting in a breakdown of polyglucosan. pbs 86-89 EPM2A glucan phosphatase, laforin Homo sapiens 96-103 24068615-6 2014 Without fountional laforin-malin complex assembled on PBs, GPBB and AGL1 together are unable to efficiently breakdown polyglucosan. pbs 54-57 EPM2A glucan phosphatase, laforin Homo sapiens 19-26 24068615-6 2014 Without fountional laforin-malin complex assembled on PBs, GPBB and AGL1 together are unable to efficiently breakdown polyglucosan. pbs 54-57 NHL repeat containing E3 ubiquitin protein ligase 1 Homo sapiens 27-32 24292556-5 2014 In live cells, SRSF3 colocalized with PDCD4 mRNA in P-bodies (PBs), where translationally silenced mRNAs are deposited, and this localization was abrogated upon SRSF3 silencing. pbs 62-65 serine and arginine rich splicing factor 3 Homo sapiens 15-20 24292556-5 2014 In live cells, SRSF3 colocalized with PDCD4 mRNA in P-bodies (PBs), where translationally silenced mRNAs are deposited, and this localization was abrogated upon SRSF3 silencing. pbs 62-65 programmed cell death 4 Homo sapiens 38-43 23815277-4 2014 Peptide-binding site (PBS) of Bogr-DRA and Bogr x BoLA-DRA was highly reserved in the alpha1 domain among all species investigated. pbs 22-25 solute carrier family 26 member 3 Homo sapiens 35-38 23815277-4 2014 Peptide-binding site (PBS) of Bogr-DRA and Bogr x BoLA-DRA was highly reserved in the alpha1 domain among all species investigated. pbs 22-25 solute carrier family 26 member 3 Homo sapiens 55-58 24227866-3 2014 We have previously shown that a PBS DNA-binding repressor complex contains ZFP809 and TRIM28. pbs 32-35 tripartite motif containing 28 Homo sapiens 86-92 24227866-4 2014 Here, we identified ErbB3-binding protein 1 (EBP1) to be a novel component of the ZFP809-TRIM28 silencing complex and show that EBP1 depletion reduces PBS-mediated retroviral silencing. pbs 151-154 proliferation-associated 2G4 Homo sapiens 20-43 24227866-4 2014 Here, we identified ErbB3-binding protein 1 (EBP1) to be a novel component of the ZFP809-TRIM28 silencing complex and show that EBP1 depletion reduces PBS-mediated retroviral silencing. pbs 151-154 proliferation-associated 2G4 Homo sapiens 45-49 24227866-4 2014 Here, we identified ErbB3-binding protein 1 (EBP1) to be a novel component of the ZFP809-TRIM28 silencing complex and show that EBP1 depletion reduces PBS-mediated retroviral silencing. pbs 151-154 tripartite motif containing 28 Homo sapiens 89-95 24227866-4 2014 Here, we identified ErbB3-binding protein 1 (EBP1) to be a novel component of the ZFP809-TRIM28 silencing complex and show that EBP1 depletion reduces PBS-mediated retroviral silencing. pbs 151-154 proliferation-associated 2G4 Homo sapiens 128-132 24672780-6 2014 Newborn cells differentiated into doublecortin (DCX-) positive neuroblasts and Neuronal Nuclei (NeuN-) positive mature neurons in the subventricular zone and ischemic boundary at higher rates in animals with MSCs-BDNF compared with treatment using solely phosphate buffered saline (PBS) or MSCs. pbs 282-285 brain derived neurotrophic factor Homo sapiens 213-217 24333060-4 2014 MATERIALS AND METHODS: We compared the binding ability of alpha-N-acetylgalactosaminidase/alpha-galactosidase with red blood cells (RBC) in different reaction buffers, such as normal saline, phosphate-buffered saline (PBS), a disodium hydrogen phosphate-based buffer (PCS), and 5% commercial glucose solution. pbs 218-221 alpha-N-acetylgalactosaminidase Homo sapiens 58-89 25430443-12 2014 Expression of NF-kappaB mRNA in the PBS group exposed to hyperoxia for 48 and 72 hours was significantly higher than the r-OPN group (P < 0.05). pbs 36-39 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 14-23 25430443-12 2014 Expression of NF-kappaB mRNA in the PBS group exposed to hyperoxia for 48 and 72 hours was significantly higher than the r-OPN group (P < 0.05). pbs 36-39 secreted phosphoprotein 1 Mus musculus 123-126 25430443-13 2014 With 72-hour exposure, expression of TIMP-1 mRNA in the r-OPN group was significantly higher than that of the PBS group (P < 0.05). pbs 110-113 tissue inhibitor of metalloproteinase 1 Mus musculus 37-43 25430443-14 2014 Expression of TIMP-2 mRNA in the r-OPN group at 48 and 72 hours was significantly higher than those in the PBS group (P < 0.05). pbs 107-110 tissue inhibitor of metalloproteinase 2 Mus musculus 14-20 25430443-15 2014 After 72-hour exposure, expression of NF-kappaB protein in airway epithelium in the PBS group was significantly higher than that in the r-OPN group (P < 0.05). pbs 84-87 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 38-47 23421766-3 2013 We have demonstrated previously that Arabidopsis AtTZF1 can localize to processing bodies (PBs) and stress granules (SGs), and affects abscisic acid (ABA)- and gibberellic acid (GA)-mediated growth, stress and gene expression responses. pbs 91-94 Zinc finger C-x8-C-x5-C-x3-H type family protein Arabidopsis thaliana 49-55 23960173-3 2013 In this study, we show that annealing of tRNA(Lys3) or a DNA oligomer complementary to sequences within the primer binding site (PBS) loop of the 5" UTR enhances its dimerization in vitro. pbs 129-132 mitochondrially encoded tRNA glycine Homo sapiens 41-50 24406137-3 2013 Tumor-bearing nude mice were assigned randomizely to three groups: Lenti-RhoA-sh group, Lenti- negative control (NC) group and phosphate buffered saline (PBS) group.lentivirus mediated RhoA shRNA, negative control lentivirus and PBS were respectively injected in the three groups. pbs 154-157 ras homolog family member A Mus musculus 185-189 23754615-6 2013 Additionally, when the mice were immunized with the Eps8 vaccine, this resulted in a regression of 4T1 breast tumors and significantly prolonged survival time in the tumor-bearing mice compared with that in the phosphate-buffered saline (PBS) control group. pbs 238-241 epidermal growth factor receptor pathway substrate 8 Mus musculus 52-56 23754615-7 2013 The Eps8 vaccine induced higher CTL responses in the splenocytes of mice vaccinated against the 4T1 cells; the ratio of CD4+/CD8+ T cells was increased in the Eps8 group; and the percentage of CD4+CD25+ FoxP3+ regulatory T (Treg) cells in the Eps8 group was significantly lower compared with that of the PBS group. pbs 304-307 epidermal growth factor receptor pathway substrate 8 Mus musculus 4-8 23421766-8 2013 Specifically, AtTZF6 can be assembled into PBs and SGs in embryos with the induction of stress hormone methyl jasmonate under the control of native AtTZF6 promoter. pbs 43-46 Zinc finger C-x8-C-x5-C-x3-H type family protein Arabidopsis thaliana 14-20 23421766-8 2013 Specifically, AtTZF6 can be assembled into PBs and SGs in embryos with the induction of stress hormone methyl jasmonate under the control of native AtTZF6 promoter. pbs 43-46 Zinc finger C-x8-C-x5-C-x3-H type family protein Arabidopsis thaliana 148-154 23833191-8 2013 Finally, we demonstrate that by fusing AtCRY2 to the TopBP1 DNA damage checkpoint protein, light-induced AtCRY2 PBs can be used to activate DNA damage signaling pathway in the absence of DNA damage. pbs 112-115 cryptochrome 2 Arabidopsis thaliana 39-45 23833191-8 2013 Finally, we demonstrate that by fusing AtCRY2 to the TopBP1 DNA damage checkpoint protein, light-induced AtCRY2 PBs can be used to activate DNA damage signaling pathway in the absence of DNA damage. pbs 112-115 DNA topoisomerase II binding protein 1 Homo sapiens 53-59 23833191-8 2013 Finally, we demonstrate that by fusing AtCRY2 to the TopBP1 DNA damage checkpoint protein, light-induced AtCRY2 PBs can be used to activate DNA damage signaling pathway in the absence of DNA damage. pbs 112-115 cryptochrome 2 Arabidopsis thaliana 105-111 23706196-5 2013 In phosphate buffer solution (PBS) of pH8.0, the oxidation current increased linearly with two concentration intervals of D-PA, one is 1.0 to 10.0 muM and, the other is 10.0 to 800.0 muM. pbs 30-33 latexin Homo sapiens 147-150 23706196-5 2013 In phosphate buffer solution (PBS) of pH8.0, the oxidation current increased linearly with two concentration intervals of D-PA, one is 1.0 to 10.0 muM and, the other is 10.0 to 800.0 muM. pbs 30-33 latexin Homo sapiens 183-186 23463546-4 2013 In every case, responses for muM-level proteins in PBS improve from the situation of not permitting molecular weight determinations to values that are precise to better than +-10 Da, without internal standards, with relative improvements in the signal-to-background ratios (S/B) on the order of 3,000x. pbs 51-54 latexin Homo sapiens 29-32 23376101-5 2013 The entrapped GOx could preserve its bioactivity and exhibited an excellent electrochemical behavior with a formal potential of -0.548 V in phosphate buffer solution (PBS) (pH=7). pbs 167-170 hydroxyacid oxidase 1 Homo sapiens 14-17 23618181-4 2013 Cyt c shows a couple of quasi-reversible and well-defined cyclic voltammetry (CV) peaks with a formal potential (E(0")) of -0.27 V (versus Ag/AgCl) in pH 7.0 phosphate buffer solution (PBS). pbs 185-188 cytochrome c, somatic Homo sapiens 0-5 23762248-1 2013 The initiation of reverse transcription of the human immunodeficiency virus type 1 (HIV-1) requires the opening of the three-dimensional structure of the primer tRNA(Lys) 3 for its annealing to the viral RNA at the primer binding site (PBS). pbs 236-239 mitochondrially encoded tRNA glycine Homo sapiens 161-172 23240585-8 2013 Hypoxic exposure increased PH, vascular remodeling, and NALP3 inflammasome activation in PBS-treated mice, while mice treated with MnTE-2-PyP showed an attenuation in each of these endpoints. pbs 89-92 NLR family, pyrin domain containing 3 Mus musculus 56-61 23274197-3 2013 L13 photonic crystal microcavities, coupled to W1 photonic crystal waveguides, are employed in which resonances show high Q in the bio-ambient phosphate buffered saline (PBS). pbs 170-173 mitochondrial ribosomal protein L13 Homo sapiens 0-3 22888964-2 2013 The annealing of 3" terminal 18 nucleotides of tRNA(3)(Lys) with the primer binding site (PBS) of viral RNA (vRNA) is crucial for reverse transcription. pbs 90-93 vault RNA 1-1 Homo sapiens 109-113 23325838-6 2013 Mice treated with VIPhyb or transplanted with VIP-KO allografts had significantly lower viral loads, increased numbers of mCMV-M45-peptide-MHC-tetramer(+) CD8(+) T-cells, with lower PD-1 expression, and enhanced primary and secondary cellular immune responses after mCMV infection than did PBS-treated mice. pbs 290-293 vasoactive intestinal peptide Homo sapiens 18-21 23223274-10 2013 The C-CP tips provided significantly higher recoveries for myoglobin in a 150 mM PBS matrix in comparison to a commercially available protein SPE product, with the added advantages of low cost, rapid processing, and reusability. pbs 81-84 myoglobin Homo sapiens 59-68 23016839-6 2013 All of the evaluated ligands were recognized by MPO at the same site, which was identified by the Q-Site Finder as being one of the principal sites and named herein as the "principal binding site" (PBS). pbs 198-201 myeloperoxidase Homo sapiens 48-51 22144226-9 2013 BC with PBs was characterized by papillary pattern of malignant cells, mucin in the background, infiltration by macrophages, cellular degeneration, overexpression of estrogen receptor (ER), and progesterone receptor (PR) and moderate positivity (2+) for Her2/neu. pbs 8-11 LOC100508689 Homo sapiens 71-76 22144226-9 2013 BC with PBs was characterized by papillary pattern of malignant cells, mucin in the background, infiltration by macrophages, cellular degeneration, overexpression of estrogen receptor (ER), and progesterone receptor (PR) and moderate positivity (2+) for Her2/neu. pbs 8-11 estrogen receptor 1 Homo sapiens 166-183 22144226-9 2013 BC with PBs was characterized by papillary pattern of malignant cells, mucin in the background, infiltration by macrophages, cellular degeneration, overexpression of estrogen receptor (ER), and progesterone receptor (PR) and moderate positivity (2+) for Her2/neu. pbs 8-11 estrogen receptor 1 Homo sapiens 185-187 22144226-9 2013 BC with PBs was characterized by papillary pattern of malignant cells, mucin in the background, infiltration by macrophages, cellular degeneration, overexpression of estrogen receptor (ER), and progesterone receptor (PR) and moderate positivity (2+) for Her2/neu. pbs 8-11 progesterone receptor Homo sapiens 194-215 22144226-9 2013 BC with PBs was characterized by papillary pattern of malignant cells, mucin in the background, infiltration by macrophages, cellular degeneration, overexpression of estrogen receptor (ER), and progesterone receptor (PR) and moderate positivity (2+) for Her2/neu. pbs 8-11 progesterone receptor Homo sapiens 217-219 22144226-9 2013 BC with PBs was characterized by papillary pattern of malignant cells, mucin in the background, infiltration by macrophages, cellular degeneration, overexpression of estrogen receptor (ER), and progesterone receptor (PR) and moderate positivity (2+) for Her2/neu. pbs 8-11 erb-b2 receptor tyrosine kinase 2 Homo sapiens 254-262 23480182-5 2013 Mice treated with PLP-cIBR had a higher secretion of cytokines related to regulatory and/or suppressor cells compared to phosphate-buffered saline (PBS)-treated mice. pbs 148-151 proteolipid protein (myelin) 1 Mus musculus 18-21 22959204-6 2013 By using label-free hairpin DNA or double-stranded DNA containing two PBS as probe, we could detect as low as 1 pg/muL of NF-kappaB in HeLa nuclear extracts, which is 10000-fold more sensitive than the previously reported methods. pbs 70-73 nuclear factor kappa B subunit 1 Homo sapiens 122-131 23260232-8 2013 Molecules in signaling cascades downstream of these cytokines were phosphorylated earlier and more robustly in the hPLT group than in the PBS group. pbs 138-141 N-acylethanolamine acid amidase Homo sapiens 115-119 23264568-4 2013 The mechanism by which tRNA(Lys3) is targeted to the PBS and released from hLysRS prior to annealing is unknown. pbs 53-56 mitochondrially encoded tRNA glycine Homo sapiens 23-32 23264568-5 2013 Here, we show that hLysRS specifically binds to a tRNA anti-codon-like element (TLE) in the HIV-1 genome, which mimics the anti-codon loop of tRNA(Lys) and is located proximal to the PBS. pbs 183-186 lysyl-tRNA synthetase 1 Homo sapiens 19-25 22900481-8 2013 In vivo, intrathecal infusion of ephrin-B3-Fc increased the proliferation of endogenous ependymal cells and the proportion of proliferating cells that expressed the glial fibrillary acidic protein astrocytic marker in the injured spinal cord compared with the infusion of PBS (P<0.05). pbs 272-275 ephrin B3 Rattus norvegicus 33-42 23245897-5 2013 A pair of quasi-reversible redox peaks of SOD with a formal potential of 0.257V was observed at SOD/GNPs-CS-IL/GCE in phosphate buffer solution (PBS, 0.1M, pH 7.0). pbs 145-148 superoxide dismutase 1 Homo sapiens 42-45 23245897-5 2013 A pair of quasi-reversible redox peaks of SOD with a formal potential of 0.257V was observed at SOD/GNPs-CS-IL/GCE in phosphate buffer solution (PBS, 0.1M, pH 7.0). pbs 145-148 superoxide dismutase 1 Homo sapiens 96-99 22888964-5 2013 It has been observed that the PNA oligomer targeted to PBS of vRNA destabilized the crucial interactions between primer and template due to which the reverse transcription is inhibited. pbs 55-58 vault RNA 1-1 Homo sapiens 62-66 22888964-8 2013 The analyses have revealed the structural changes in PBS region of vRNA which might be another strong reason for the inability of RT binding to 7F helix for its normal functioning of reverse transcription. pbs 53-56 vault RNA 1-1 Homo sapiens 67-71 22488927-5 2012 RESULTS: Compared to healthy donors the average frequency of PBs among total peripheral blood lymphocytes is increased 30-fold during severe UC activity, and positively correlates with Pediatric Ulcerative Colitis Activity Index score, C-reactive protein level, and erythrocyte sedimentation rate. pbs 61-64 C-reactive protein Homo sapiens 236-254 23025713-9 2012 IL-1beta levels were 99.71 +- 85.22 and 230.76 +- 102.67 pg/ml in the UCS and PBS groups, respectively (p = 0.03). pbs 78-81 interleukin 1 beta Mus musculus 0-8 22488927-6 2012 A greater percent of PBs in severe patients express the gut-homing receptors alpha4beta7 and CCR10, and the inflammatory homing molecule P-selectin ligand (P-sel lig). pbs 21-24 C-C motif chemokine receptor 10 Homo sapiens 93-98 22488927-6 2012 A greater percent of PBs in severe patients express the gut-homing receptors alpha4beta7 and CCR10, and the inflammatory homing molecule P-selectin ligand (P-sel lig). pbs 21-24 selectin P ligand Homo sapiens 156-165 22488927-8 2012 Furthermore, expression of the small intestine TR CCR9 is decreased on alpha4beta7(high) PBs, and on alpha4beta7(high) /CCR10(high) PBs and MBCs in these patients, consistent with preferential cell targeting to the colon. pbs 89-92 C-C motif chemokine receptor 9 Homo sapiens 50-54 22488927-8 2012 Furthermore, expression of the small intestine TR CCR9 is decreased on alpha4beta7(high) PBs, and on alpha4beta7(high) /CCR10(high) PBs and MBCs in these patients, consistent with preferential cell targeting to the colon. pbs 132-135 C-C motif chemokine receptor 9 Homo sapiens 50-54 22488927-9 2012 CONCLUSIONS: Peripheral blood PBs with a colon-homing phenotype (alpha4beta7/CCR10/P-sel lig) are elevated in children with severe UC. pbs 30-33 C-C motif chemokine receptor 10 Homo sapiens 77-82 22488927-9 2012 CONCLUSIONS: Peripheral blood PBs with a colon-homing phenotype (alpha4beta7/CCR10/P-sel lig) are elevated in children with severe UC. pbs 30-33 selectin P ligand Homo sapiens 83-92 22705082-5 2012 The recovery of MS2 from cellulose sponges using beef extract was significantly higher (P=0.001) than tryptose phosphate glycine broth which was significantly higher (P=0.0001) than PBS. pbs 182-185 MS2 Homo sapiens 16-19 22966201-2 2012 PBs concentrate nontranslated mRNAs and several factors involved in mRNA decay and translational repression, including the eukaryotic translation initiation factor 4E-transporter (4E-T). pbs 0-3 eukaryotic translation initiation factor 4E nuclear import factor 1 Homo sapiens 180-184 22966201-5 2012 We show that the c-Jun N-terminal kinase (JNK) is targeted to PBs in response to oxidative stress and promotes the phosphorylation of 4E-T. pbs 62-65 mitogen-activated protein kinase 8 Homo sapiens 17-40 22966201-5 2012 We show that the c-Jun N-terminal kinase (JNK) is targeted to PBs in response to oxidative stress and promotes the phosphorylation of 4E-T. pbs 62-65 mitogen-activated protein kinase 8 Homo sapiens 42-45 22966201-5 2012 We show that the c-Jun N-terminal kinase (JNK) is targeted to PBs in response to oxidative stress and promotes the phosphorylation of 4E-T. pbs 62-65 eukaryotic translation initiation factor 4E nuclear import factor 1 Homo sapiens 134-138 22966201-7 2012 We have developed an image-based computational method to quantify the size, number, and density of PBs in cells, and we find that while 4E-T is required for steady-state PB assembly, its phosphorylation facilitates the formation of larger PBs upon oxidative stress. pbs 99-102 eukaryotic translation initiation factor 4E nuclear import factor 1 Homo sapiens 136-140 22907799-3 2012 Comparative studies revealed that the catalytic activity of tyrosinase for phenol in phosphate buffer solution (PBS) containing EMIM[Ala] was about ten times higher than that in pure PBS. pbs 112-115 tyrosinase Homo sapiens 60-70 22907799-3 2012 Comparative studies revealed that the catalytic activity of tyrosinase for phenol in phosphate buffer solution (PBS) containing EMIM[Ala] was about ten times higher than that in pure PBS. pbs 183-186 tyrosinase Homo sapiens 60-70 22426154-3 2012 Additionally, urotensin II induced c-Fos-like-immunoreactivity (c-FLI) in the paraventricular nucleus (PVN) as compared with that in the control (phosphate buffered saline [PBS]-treated) group. pbs 173-176 urotensin 2 Rattus norvegicus 14-26 22868612-4 2012 The collagen fibrils in the IL-1Ra groups were morphologically more similar to those in the control group than to those in the PBS groups. pbs 127-130 interleukin 1 receptor antagonist Rattus norvegicus 28-34 22868612-7 2012 The MMP-1 level increased dramatically after stress shielding and increased less in the 2-week IL-1Ra group than in the 2-week PBS group. pbs 127-130 matrix metallopeptidase 1 Rattus norvegicus 4-9 22868612-8 2012 The degree of decrease of MMP-3 in the IL-1Ra groups was significantly less than that in the PBS groups. pbs 93-96 matrix metallopeptidase 3 Rattus norvegicus 26-31 23157908-15 2012 Compared with Ad-LRIG1 group and PBS group, the mRNA expression of LRIG1 was obviously up-regulated and that of EGFR was down-regulated in Ad-Surp-LRIG1 group (P < 0.01). pbs 33-36 leucine rich repeats and immunoglobulin like domains 1 Homo sapiens 67-72 23157908-15 2012 Compared with Ad-LRIG1 group and PBS group, the mRNA expression of LRIG1 was obviously up-regulated and that of EGFR was down-regulated in Ad-Surp-LRIG1 group (P < 0.01). pbs 33-36 epidermal growth factor receptor Homo sapiens 112-116 23157908-15 2012 Compared with Ad-LRIG1 group and PBS group, the mRNA expression of LRIG1 was obviously up-regulated and that of EGFR was down-regulated in Ad-Surp-LRIG1 group (P < 0.01). pbs 33-36 leucine rich repeats and immunoglobulin like domains 1 Homo sapiens 67-72 22487850-7 2012 Tumor necrosis factor-alpha mRNA transcripts, but not interferon-gamma, were detected early in spleen cells of pretreated mice after infection; however, the nitric oxide contents in the bloodstream were decreased in comparison to the PBS group. pbs 234-237 tumor necrosis factor Mus musculus 0-27 22883203-6 2012 RESULTS: The expression of TLR4 in hPBMC treated with rBCG or wBCG were stronger than that treat with PBS (all P < 0.05). pbs 102-105 toll like receptor 4 Homo sapiens 27-31 22883203-7 2012 In TLR4 non-blocking groups the expressions of hTNF-alpha and hIFN-gamma were rBCG group > wBCG group > hIFN-alpha-2b group > PBS group, the expressions of hIL-12 was hIFN-alpha-2b group > PBS group > rBCG group > wBCG group (all P < 0.05). pbs 135-138 toll like receptor 4 Homo sapiens 3-7 22883203-7 2012 In TLR4 non-blocking groups the expressions of hTNF-alpha and hIFN-gamma were rBCG group > wBCG group > hIFN-alpha-2b group > PBS group, the expressions of hIL-12 was hIFN-alpha-2b group > PBS group > rBCG group > wBCG group (all P < 0.05). pbs 201-204 toll like receptor 4 Homo sapiens 3-7 22883203-7 2012 In TLR4 non-blocking groups the expressions of hTNF-alpha and hIFN-gamma were rBCG group > wBCG group > hIFN-alpha-2b group > PBS group, the expressions of hIL-12 was hIFN-alpha-2b group > PBS group > rBCG group > wBCG group (all P < 0.05). pbs 201-204 tumor necrosis factor Homo sapiens 47-57 22883203-7 2012 In TLR4 non-blocking groups the expressions of hTNF-alpha and hIFN-gamma were rBCG group > wBCG group > hIFN-alpha-2b group > PBS group, the expressions of hIL-12 was hIFN-alpha-2b group > PBS group > rBCG group > wBCG group (all P < 0.05). pbs 201-204 interferon gamma Homo sapiens 62-72 22579916-10 2012 Compared to ACLT + exercise and PBS-treated ACLT + exercise, lubricin intra-articular treatment resulted in a significant increase (P < 0.001) in cartilage lubricin gene expression and a reduction (P < 0.05) in uCTXII levels. pbs 32-35 proteoglycan 4 Homo sapiens 61-69 22537808-4 2012 As C(60) molecules conjugated to GC increased to 0.16 molecules per one repeating unit of GC, GC-g-C(60) started to form supramolecular assemblies (~30 nm) stabilized in phosphate buffer saline (PBS, 150 mM, pH 7.4). pbs 195-198 glucagon Mus musculus 94-98 22522742-2 2012 L13 photonic crystal microcavities are employed which show high Q values (~9300) in the bio-ambient phosphate buffered saline (PBS) as well as high sensitivity, experimentally demonstrated to ~98 atto-grams. pbs 127-130 mitochondrial ribosomal protein L13 Homo sapiens 0-3 22247403-11 2012 A Spearman rho correlation of .700 indicated a statistical association between PBS and ASKp postintervention scores (P=.003). pbs 79-82 arylsulfatase family member K Homo sapiens 87-91 22127873-9 2012 RESULTS: Increased immunostaining for lubricin in the superficial zone and on the surface of cartilage was observed in lubricin-treated and control animals but not in PBS-treated or untreated animals with ACLT. pbs 167-170 proteoglycan 4 Rattus norvegicus 38-46 22127873-11 2012 Animals with ACLT treated with human synoviocyte lubricin and control animals distributed their weight equally between hind limbs compared to PBS-treated or untreated animals (P < 0.01). pbs 142-145 proteoglycan 4 Homo sapiens 49-57 25745457-10 2012 (3) By comparing the staining intensity in the vasculature of COH retina in LBP-fed group with PBS-fed group, there was a decrease in the expression of ET-1 and ETA and an increase in ETB. pbs 95-98 endothelin 1 Rattus norvegicus 152-164 25745457-10 2012 (3) By comparing the staining intensity in the vasculature of COH retina in LBP-fed group with PBS-fed group, there was a decrease in the expression of ET-1 and ETA and an increase in ETB. pbs 95-98 endothelin receptor type B Rattus norvegicus 184-187 22566872-9 2011 Removal of CpG ODN during differentiation induced a decrease in the CD20+ plasmablastic population, and, conversely, stimulation of CD40L-induced pre-plasmablasts with CpG ODN increased the population of CD20+CD38+ PBs. pbs 215-218 CD40 ligand Homo sapiens 132-137 22490699-8 2012 The levels of mRNA and protein of eNOS were higher in the 100 microg IGF-1 treatment group versus the PBS-only group at Week 4 (0.62 +- 0.16 vs 0.25 +- 0.08, 0.71 +- 0.19 vs 0.27 +- 0.09, both P < 0.05, respectively). pbs 102-105 nitric oxide synthase 3 Rattus norvegicus 34-38 22490699-8 2012 The levels of mRNA and protein of eNOS were higher in the 100 microg IGF-1 treatment group versus the PBS-only group at Week 4 (0.62 +- 0.16 vs 0.25 +- 0.08, 0.71 +- 0.19 vs 0.27 +- 0.09, both P < 0.05, respectively). pbs 102-105 insulin-like growth factor 1 Rattus norvegicus 69-74 21672073-1 2012 Progressive aggregation of alpha-synuclein (alphaS) from pale bodies (PBs) and extension from Lewy neurites (LNs) are candidate mechanisms for Lewy body (LB) formation. pbs 70-73 synuclein alpha Homo sapiens 27-42 22590546-8 2012 We found that, in several cell lines, including U2OS, WI38, SK-N-SH and HCT116, the Pab 1801 puncta strictly colocalize with PBs identified with specific antibodies against the PB components Hedls, Dcp1a, Xrn1 or Rck/p54. pbs 125-128 decapping mRNA 1A Homo sapiens 198-203 22590546-8 2012 We found that, in several cell lines, including U2OS, WI38, SK-N-SH and HCT116, the Pab 1801 puncta strictly colocalize with PBs identified with specific antibodies against the PB components Hedls, Dcp1a, Xrn1 or Rck/p54. pbs 125-128 5'-3' exoribonuclease 1 Homo sapiens 205-209 22590546-8 2012 We found that, in several cell lines, including U2OS, WI38, SK-N-SH and HCT116, the Pab 1801 puncta strictly colocalize with PBs identified with specific antibodies against the PB components Hedls, Dcp1a, Xrn1 or Rck/p54. pbs 125-128 mitogen-activated protein kinase kinase kinase 19 Homo sapiens 213-216 22590546-8 2012 We found that, in several cell lines, including U2OS, WI38, SK-N-SH and HCT116, the Pab 1801 puncta strictly colocalize with PBs identified with specific antibodies against the PB components Hedls, Dcp1a, Xrn1 or Rck/p54. pbs 125-128 interferon induced protein with tetratricopeptide repeats 2 Homo sapiens 217-220 22566872-9 2011 Removal of CpG ODN during differentiation induced a decrease in the CD20+ plasmablastic population, and, conversely, stimulation of CD40L-induced pre-plasmablasts with CpG ODN increased the population of CD20+CD38+ PBs. pbs 215-218 keratin 20 Homo sapiens 204-208 21613289-8 2011 CS-A microspheres with a core-shell structure showed a significant decrease in the burst release of proteins, maintaining sustained release profile in phosphate-buffered saline (PBS) at both pH 7.4 and 4.3, compared with the controls. pbs 178-181 chorionic somatomammotropin hormone 1 Homo sapiens 0-4 22360827-6 2011 Ovariectomized mice with AAT treatment had higher uterus weight, lower serum osteocalcin levels, fewer bone marrow tartrate-resistant acid phosphatase-positive osteoclasts, and less expression of calcitonin receptor in bone than that in PBS-injected mice. pbs 237-240 serine (or cysteine) preptidase inhibitor, clade A, member 1B Mus musculus 25-28 21859890-7 2011 This search identified miR-494 as a microRNA that potently inhibited nucleolin expression, enhanced NCL mRNA association with argonaute-containing complexes, and induced NCL RNA transport to PBs. pbs 191-194 microRNA 494 Homo sapiens 23-30 21812471-1 2011 A bienzymatic electrode incorporating trehalase (Tre) and glucose oxidase (GOx) covalently bound to the surface of Pt through a functionalized thiol linker (Tre GOx Pt) has been designed and assembled and its catalytic properties examined by chemical and electrochemical methods in aqueous phosphate buffer solutions (PBS, pH 7.4). pbs 318-321 trehalase Homo sapiens 38-47 21812471-1 2011 A bienzymatic electrode incorporating trehalase (Tre) and glucose oxidase (GOx) covalently bound to the surface of Pt through a functionalized thiol linker (Tre GOx Pt) has been designed and assembled and its catalytic properties examined by chemical and electrochemical methods in aqueous phosphate buffer solutions (PBS, pH 7.4). pbs 318-321 hydroxyacid oxidase 1 Homo sapiens 58-73 21812471-1 2011 A bienzymatic electrode incorporating trehalase (Tre) and glucose oxidase (GOx) covalently bound to the surface of Pt through a functionalized thiol linker (Tre GOx Pt) has been designed and assembled and its catalytic properties examined by chemical and electrochemical methods in aqueous phosphate buffer solutions (PBS, pH 7.4). pbs 318-321 hydroxyacid oxidase 1 Homo sapiens 75-78 21812471-2 2011 Exposure of Tre GOx Pt to PBS containing trehalose (Tr) and subsequent polarization at 0.6 V versus Ag/AgCl yielded after a few minutes well-defined steady-state currents ascribed to the oxidation of hydrogen peroxide generated by the GOx-mediated oxidation of glucose (Gl) produced by the Tre-mediated dissociation of Tr. pbs 26-29 trehalase Homo sapiens 12-15 21812471-2 2011 Exposure of Tre GOx Pt to PBS containing trehalose (Tr) and subsequent polarization at 0.6 V versus Ag/AgCl yielded after a few minutes well-defined steady-state currents ascribed to the oxidation of hydrogen peroxide generated by the GOx-mediated oxidation of glucose (Gl) produced by the Tre-mediated dissociation of Tr. pbs 26-29 hydroxyacid oxidase 1 Homo sapiens 16-19 21859890-7 2011 This search identified miR-494 as a microRNA that potently inhibited nucleolin expression, enhanced NCL mRNA association with argonaute-containing complexes, and induced NCL RNA transport to PBs. pbs 191-194 nucleolin Homo sapiens 170-173 21562126-11 2011 Gal-9 down-regulated CD14 on pDC-like macrophages from PBS-treated mice independently of Gal-9/Tim-3 (T-cell immunoglobulin- and mucin domain-containing molecule-3) interaction, resulting in the acquisition of suppressive function, suggesting that the loss of CD14 by Gal-9 is critical for the suppression of pDC-like macrophages. pbs 55-58 lectin, galactose binding, soluble 9 Mus musculus 0-5 21671795-3 2011 Behavioral analysis and electrophysiological H-reflex recordings revealed that mice transplanted with GFAP-L1 NSCs showed enhanced locomotor recovery in comparison to mice injected with wild type (WT) NSCs or control mice injected with phosphate-buffered saline (PBS). pbs 263-266 glial fibrillary acidic protein Mus musculus 102-106 21562126-7 2011 CD11b(+)Gr-1(+) cells were increased in the spleen of both Gal-9-treated and phosphate-buffered saline (PBS)-treated ALI mice, but only Gal-9 increased the ability of CCR2-expressing macrophages to migrate toward monocyte chemoattractant protein-1. pbs 104-107 integrin subunit alpha M Homo sapiens 0-5 21562126-11 2011 Gal-9 down-regulated CD14 on pDC-like macrophages from PBS-treated mice independently of Gal-9/Tim-3 (T-cell immunoglobulin- and mucin domain-containing molecule-3) interaction, resulting in the acquisition of suppressive function, suggesting that the loss of CD14 by Gal-9 is critical for the suppression of pDC-like macrophages. pbs 55-58 CD14 antigen Mus musculus 21-25 21501850-5 2011 Fasudil treatment was associated with a significant reduction in secretion of IFN-gamma; by contrast, secretion of IL-4 was almost the same in the fasudil- and PBS-treated groups. pbs 160-163 interleukin 4 Rattus norvegicus 115-119 21501850-6 2011 As a result, the IFN-gamma/IL-4 ratio in the supernatant was significantly deceased in fasudil-treated rats compared with PBS-treated ones. pbs 122-125 interferon gamma Rattus norvegicus 17-26 21501850-6 2011 As a result, the IFN-gamma/IL-4 ratio in the supernatant was significantly deceased in fasudil-treated rats compared with PBS-treated ones. pbs 122-125 interleukin 4 Rattus norvegicus 27-31 21894256-10 2011 RESULTS: Compared to both the PBS-treated and untreated control groups, statistically significant (p < 0.05) upregulation of MMP8 was observed in the 6-hour time point. pbs 30-33 matrix metallopeptidase 8 Mus musculus 128-132 21702950-6 2011 RESULTS: We show for the first time that the Rev/RRE system can augment RNA encapsidation independent of all cis elements from the 5" UTR (R, U5, PBS, and psi). pbs 146-149 Rev Human immunodeficiency virus 1 45-48 21392113-7 2011 Mice receiving CD4(+) CD25(+) cells from mice vaccinated with PDT-induced apoptotic MPhi showed smaller lesions 3 weeks after infection and lower parasitic burdens than mice that received Tregs from mice of thaw-frozen necrotic MPhi or PBS groups. pbs 236-239 CD4 antigen Mus musculus 15-18 21268025-2 2011 A sufficient glucose sensitivity of the copolymer was accomplished by the glucose-induced volume changes of the nanoparticles and release profiles of insulin in phosphate buffered saline (PBS, pH 7.4) with different glucose concentrations, which occurred in a remarkable glucose concentration-dependent manner. pbs 188-191 insulin Homo sapiens 150-157 20616358-5 2011 EMAPII significantly increased compaction rate and decreased overall cohesion of PBs composed of both epithelial and mesenchymal cells. pbs 81-84 aminoacyl tRNA synthetase complex interacting multifunctional protein 1 Homo sapiens 0-6 21148147-2 2011 Human Argonaute 2 (hAgo2), the catalytic core component of the RNA-induced silencing complex (RISC), can be recruited to SGs as well as P-bodies (PBs) indicating that the dynamic intracellular distribution of hAgo2 in SGs, in PBs or at other sub-cellular sites could be related to the efficiency of the RNA interference (RNAi) machinery. pbs 146-149 argonaute RISC catalytic component 2 Homo sapiens 6-17 21148147-2 2011 Human Argonaute 2 (hAgo2), the catalytic core component of the RNA-induced silencing complex (RISC), can be recruited to SGs as well as P-bodies (PBs) indicating that the dynamic intracellular distribution of hAgo2 in SGs, in PBs or at other sub-cellular sites could be related to the efficiency of the RNA interference (RNAi) machinery. pbs 146-149 argonaute RISC catalytic component 2 Homo sapiens 19-24 21148147-2 2011 Human Argonaute 2 (hAgo2), the catalytic core component of the RNA-induced silencing complex (RISC), can be recruited to SGs as well as P-bodies (PBs) indicating that the dynamic intracellular distribution of hAgo2 in SGs, in PBs or at other sub-cellular sites could be related to the efficiency of the RNA interference (RNAi) machinery. pbs 226-229 argonaute RISC catalytic component 2 Homo sapiens 6-17 21148147-2 2011 Human Argonaute 2 (hAgo2), the catalytic core component of the RNA-induced silencing complex (RISC), can be recruited to SGs as well as P-bodies (PBs) indicating that the dynamic intracellular distribution of hAgo2 in SGs, in PBs or at other sub-cellular sites could be related to the efficiency of the RNA interference (RNAi) machinery. pbs 226-229 argonaute RISC catalytic component 2 Homo sapiens 19-24 21521205-17 2011 Both IS and PBS increased expression of mRNAs encoding CGRP, RAMP1, RCP, and CLR in the trigeminal ganglion in males, but in females, only CLR and RCP were increased. pbs 12-15 calcitonin-related polypeptide alpha Rattus norvegicus 55-59 21521205-17 2011 Both IS and PBS increased expression of mRNAs encoding CGRP, RAMP1, RCP, and CLR in the trigeminal ganglion in males, but in females, only CLR and RCP were increased. pbs 12-15 receptor activity modifying protein 1 Rattus norvegicus 61-66 21521205-18 2011 In the medulla both IS and PBS increased expression of CGRP, CLR in males and CLR and RCP in females. pbs 27-30 calcitonin-related polypeptide alpha Rattus norvegicus 55-59 21521205-20 2011 Instead, CGRP-related genes were upregulated by both IS and PBS applications. pbs 60-63 calcitonin-related polypeptide alpha Rattus norvegicus 9-13 21521205-22 2011 In addition, there were prominent baseline sex differences in expression of CGRP and its receptor in both the trigeminal ganglion and medulla, but the majority of changes in expression of CGRP and its receptor were present in both the IS and PBS treated rats. pbs 242-245 calcitonin-related polypeptide alpha Rattus norvegicus 188-192 21354778-6 2011 On the other hand, the quantification of glucose in 0.1M PBS (pH 7.4) containing 0.1M NaCl offered an extended linear range from 10 muM to 11 mM with a sensitivity of 66.0 muA mM(-1)cm(-2) and a low detection limit of 8.7 muM (signal-to-noise ratio of 3) at a detection potential of 0.2V. pbs 57-60 latexin Homo sapiens 132-135 21354778-6 2011 On the other hand, the quantification of glucose in 0.1M PBS (pH 7.4) containing 0.1M NaCl offered an extended linear range from 10 muM to 11 mM with a sensitivity of 66.0 muA mM(-1)cm(-2) and a low detection limit of 8.7 muM (signal-to-noise ratio of 3) at a detection potential of 0.2V. pbs 57-60 latexin Homo sapiens 222-225 21285021-13 2011 Additionally, alpha-smooth muscle actin immunopositivity was found significantly decreased in anastomosed arteries from ZA group (ZA: 2.33+-0.52 vs. PBS: 3.50+-0.5, p<0.05). pbs 149-152 actin, aortic smooth muscle Oryctolagus cuniculus 14-39 21600178-12 2011 And the level of IFN-gamma was significantly higher in LPS group than that in PBS, RAPA and LPS + RAPA groups by co-culture (P < 0.05). pbs 78-81 interferon gamma Mus musculus 17-26 21600178-14 2011 However, the mRNA of IFN-gamma was higher in LPS group than that in PBS and RAPA groups (P < 0.05). pbs 68-71 interferon gamma Mus musculus 21-30 21285021-14 2011 Moreover, intensive gelatinase (MMP-2 and MMP-9) immunoreactivities were clearly seen in anastomosed arteries compared to control arteries from PBS group. pbs 144-147 72 kDa type IV collagenase Oryctolagus cuniculus 32-37 21285021-14 2011 Moreover, intensive gelatinase (MMP-2 and MMP-9) immunoreactivities were clearly seen in anastomosed arteries compared to control arteries from PBS group. pbs 144-147 matrix metalloproteinase-9 Oryctolagus cuniculus 42-47 20665697-10 2011 These findings suggest that seizing entails lasting changes in hippocampus area CA1 so that LTP induction by PBs is masked due to intensive adenosine release which in turn prevents TPS to induce PS LTD in epileptic CA1 network. pbs 109-112 carbonic anhydrase 1 Rattus norvegicus 80-83 21221728-3 2011 Albumin increased significantly corrosion of both alloys in PBS solutions while its effect in NaCl was smaller. pbs 60-63 albumin Homo sapiens 0-7 21525716-3 2011 Using biophysical methods, we investigated the interaction between the 32-kDa enamelin and recombinant pig amelogenin 148 (rP148) at pH 6.5 in phosphate-buffered saline (PBS). pbs 170-173 enamelin Sus scrofa 78-86 21456131-2 2011 The PArg/MWCNTs/GCE exhibited high electro-catalytic activities towards the oxidation of 3,4-dihydroxyphenylacetic acid (DOPAC), uric acid (UA), and ascorbic acid (AA), and could be sensitively used for simultaneous determination of DOPAC, AA, and UA in pH 7.4 phosphate-buffered solution (PBS).The linear ranges were 7 microM to 2.7 mM for DOPAC, 3 microM to 1.2 mM for UA, and 70 microM to 1.4 mM for AA. pbs 290-293 poly(ADP-ribose) glycohydrolase Homo sapiens 4-8 21525716-7 2011 Our results demonstrate that the 32-kDa enamelin has a close association with amelogenin at pH 6.5 in PBS buffer. pbs 102-105 enamelin Sus scrofa 40-48 21525716-7 2011 Our results demonstrate that the 32-kDa enamelin has a close association with amelogenin at pH 6.5 in PBS buffer. pbs 102-105 amelogenin Sus scrofa 78-88 20592225-5 2010 RESULTS: Injection of B6 mice with VIP compared with PBS resulted in significant downregulation of intercellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule (VCAM)-1, platelet-endothelial cell adhesion molecule-1, and P-selectin and L-selectin mRNA expression. pbs 53-56 vasoactive intestinal polypeptide Mus musculus 35-38 20717888-7 2011 PBS as the reaction buffer resulted in higher amounts of VEGF and Ang1 immobilized (ELISA), higher cell proliferation rates (XTT) and increased lactate metabolism compared to water and MES as the reaction buffers. pbs 0-3 vascular endothelial growth factor A Rattus norvegicus 57-61 20717888-7 2011 PBS as the reaction buffer resulted in higher amounts of VEGF and Ang1 immobilized (ELISA), higher cell proliferation rates (XTT) and increased lactate metabolism compared to water and MES as the reaction buffers. pbs 0-3 angiopoietin 1 Rattus norvegicus 66-70 20720575-4 2010 At 1 month post-treatment, the levels of nuclear NF-kappaB in locally treated muscle were decreased by gene transfer with either AAV-CMV-IKKalpha-dn or AAV-CMV-IKKbeta-dn, but not by IKK wild-type controls (IKKalpha and beta) or phosphate-buffered saline (PBS). pbs 256-259 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 49-58 21789200-4 2011 Ovalbumin (OVA)-sensitized mice were treated with live A. baumannii or phosphate buffered saline (PBS), then intranasally challenged with OVA. pbs 98-101 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 0-9 20813405-6 2010 Experiments in a collagen-induced arthritis mouse model demonstrated that the magnitudes of therapeutic effects, as judged by clinical scores and histology, were significantly enhanced by the sustained delivery of PEG-TRAIL, with the order of nanocomplex in 1% HA>nanocomplex in PBS>PEG-TRAIL in PBS. pbs 282-285 tumor necrosis factor (ligand) superfamily, member 10 Mus musculus 214-223 20813405-6 2010 Experiments in a collagen-induced arthritis mouse model demonstrated that the magnitudes of therapeutic effects, as judged by clinical scores and histology, were significantly enhanced by the sustained delivery of PEG-TRAIL, with the order of nanocomplex in 1% HA>nanocomplex in PBS>PEG-TRAIL in PBS. pbs 282-285 tumor necrosis factor (ligand) superfamily, member 10 Mus musculus 218-223 20813405-6 2010 Experiments in a collagen-induced arthritis mouse model demonstrated that the magnitudes of therapeutic effects, as judged by clinical scores and histology, were significantly enhanced by the sustained delivery of PEG-TRAIL, with the order of nanocomplex in 1% HA>nanocomplex in PBS>PEG-TRAIL in PBS. pbs 302-305 tumor necrosis factor (ligand) superfamily, member 10 Mus musculus 214-223 20813405-6 2010 Experiments in a collagen-induced arthritis mouse model demonstrated that the magnitudes of therapeutic effects, as judged by clinical scores and histology, were significantly enhanced by the sustained delivery of PEG-TRAIL, with the order of nanocomplex in 1% HA>nanocomplex in PBS>PEG-TRAIL in PBS. pbs 302-305 tumor necrosis factor (ligand) superfamily, member 10 Mus musculus 218-223 20592225-5 2010 RESULTS: Injection of B6 mice with VIP compared with PBS resulted in significant downregulation of intercellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule (VCAM)-1, platelet-endothelial cell adhesion molecule-1, and P-selectin and L-selectin mRNA expression. pbs 53-56 intercellular adhesion molecule 1 Mus musculus 99-139 20592225-5 2010 RESULTS: Injection of B6 mice with VIP compared with PBS resulted in significant downregulation of intercellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule (VCAM)-1, platelet-endothelial cell adhesion molecule-1, and P-selectin and L-selectin mRNA expression. pbs 53-56 vascular cell adhesion molecule 1 Mus musculus 141-181 20592225-5 2010 RESULTS: Injection of B6 mice with VIP compared with PBS resulted in significant downregulation of intercellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule (VCAM)-1, platelet-endothelial cell adhesion molecule-1, and P-selectin and L-selectin mRNA expression. pbs 53-56 platelet/endothelial cell adhesion molecule 1 Mus musculus 183-228 20592225-7 2010 Immunofluorescence staining further confirmed the effects of VIP treatment, showing reduced corneal expression of ICAM-1/leukocyte function-associated antigen (LFA-1) and VCAM-1/very late antigen-4 (VLA-4) at select time points compared with PBS-treated animals. pbs 242-245 vasoactive intestinal polypeptide Mus musculus 61-64 20141586-16 2010 Neuronal nitric oxide synthase (nNOS)-positive nerve fibers and endothelial cells were fewer in HR + PBS than in HR + ADSC. pbs 101-104 nitric oxide synthase 1 Rattus norvegicus 0-30 20652561-7 2010 In both PBS and urine, mOPN was attached to the {021} faces of pre-formed iCOM crystals as well as to the {100}/{010} edges, but was concentrated at the intersection points of the {100} and {121} faces at the crystal tips. pbs 8-11 secreted phosphoprotein 1 Mus musculus 23-27 20854734-4 2010 RESULTS: Compared with PBS control group, the TNF-alpha content (ng/L) in LPS treated group was significantly increased (650.26+-40.53 vs. 6.23+-1.76, P<0.01), and miRNA-146a in LPS treated group increased by about (5.33+-0.81) folds (P<0.01). pbs 23-26 tumor necrosis factor Rattus norvegicus 46-55 20610036-6 2010 The number of new neurons co-stained with BrdU and betaIII-tubulin was also significantly increased in the neostriata of BDNF/EGF-treated mice, compared with PBS group. pbs 158-161 brain derived neurotrophic factor Mus musculus 121-125 20610036-6 2010 The number of new neurons co-stained with BrdU and betaIII-tubulin was also significantly increased in the neostriata of BDNF/EGF-treated mice, compared with PBS group. pbs 158-161 epidermal growth factor Mus musculus 126-129 20610036-9 2010 When evaluated post-surgical 8 weeks, BDNF/EGF-treated mice exhibited significantly longer rotarod latencies at constant speed (48 rpm) and under accelerating condition (4-80 rpm), relative to PBS and untreated controls. pbs 193-196 brain derived neurotrophic factor Mus musculus 38-42 20610036-9 2010 When evaluated post-surgical 8 weeks, BDNF/EGF-treated mice exhibited significantly longer rotarod latencies at constant speed (48 rpm) and under accelerating condition (4-80 rpm), relative to PBS and untreated controls. pbs 193-196 epidermal growth factor Mus musculus 43-46 20466563-9 2010 Infarct size and fibrotic area decreased significantly (p < 0.05) in the chitosan+bFGF group (39.64 +/- 1.75% and 25.09 +/- 3.31%, respectively) compared with the PBS+bFGF group (48.91 +/- 1.39% and 48.0 +/- 3.83%, respectively; n = 8 per group). pbs 166-169 fibroblast growth factor 2 Rattus norvegicus 85-89 20618702-11 2010 Lastly, it was demonstrated that immunoprecipitation of Annexin-A1 from proteins extracted from PBS-treated oral epithelial cells resulted in abrogation of inhibitory activity. pbs 96-99 annexin A1 Homo sapiens 56-66 20367582-4 2010 MAIN OUTCOME MEASURES: Prevalence of CD and PCD in patients attending different IBD centres; eligibility of PCD patients for PBS-subsidised anti-TNFalpha medication. pbs 125-128 tumor necrosis factor Homo sapiens 145-153 20444326-9 2010 The number of viable neurons in the CA1 field of the rhEPO-treated (103.57 +- 27.90 cells/mm) and asialoEPO-treated (144.99 +- 34.87 cells/mm) animals was higher than that of the PBS-treated animals (19.53 +- 3.79 cells/mm). pbs 179-182 carbonic anhydrase 1 Homo sapiens 36-39 20600853-3 2010 However, the PDE4 inhibitor rolipram decreases arsenite-induced SGs and increases the amount of PBs, while arsenite challenge ablates rolipram-induced PDE4A4 aggregates. pbs 96-99 phosphodiesterase 4A Homo sapiens 13-17 20232361-8 2010 RESULTS: Throughout the entire course, the average size of PC3 tumors in ADSC-treated mice was larger than in PBS-treated mice. pbs 110-113 chromobox 8 Mus musculus 59-62 20232361-12 2010 VEGF expression was similar but FGF2 expression was significantly higher in tumors of ADSC-treated mice than in the tumors of PBS-tread mice. pbs 126-129 fibroblast growth factor 2 Mus musculus 32-36 20514637-12 2010 CONCLUSIONS: The PBS presence in MCI patients is associated with ATD progression with or without ApoE epsilon4 allele. pbs 17-20 apolipoprotein E Homo sapiens 97-101 20141586-16 2010 Neuronal nitric oxide synthase (nNOS)-positive nerve fibers and endothelial cells were fewer in HR + PBS than in HR + ADSC. pbs 101-104 nitric oxide synthase 1 Rattus norvegicus 32-36 19897605-4 2010 Human TZF binds AU-rich elements at the 3" untranslated region and recruits decapping, deadenylation, and exonucleolytic enzymes to PBs for RNA turnover. pbs 132-135 zinc finger protein 318 Homo sapiens 6-9 20023317-4 2010 The bioconjugated clusters show excellent stability over a wide range of pH from 4 to 14 and fluorescence efficiency of approximately 5.7% at pH 7.4 in phosphate buffer saline (PBS), indicating effective protection of nanoclusters by serum albumin during the bioconjugation reaction and cell-cluster interaction. pbs 177-180 albumin Homo sapiens 234-247 19897605-11 2010 AtTZF1 colocalizes with markers of PBs, and the morphology of these cytoplasmic foci resembles that of mammalian PBs and stress granules. pbs 35-38 Zinc finger C-x8-C-x5-C-x3-H type family protein Arabidopsis thaliana 0-6 19897605-11 2010 AtTZF1 colocalizes with markers of PBs, and the morphology of these cytoplasmic foci resembles that of mammalian PBs and stress granules. pbs 113-116 Zinc finger C-x8-C-x5-C-x3-H type family protein Arabidopsis thaliana 0-6 20047725-4 2010 Microinjection of KRT18 double-stranded RNA into the cytoplasm of zygotes resulted in reduced KRT18 mRNA (76% reduction) and protein expression at the blastocyst stage and a lower developmental competence (41% reduction in the percentage of blastocyst formation) compared with non-injected and phosphate-buffered saline (PBS)-injected controls. pbs 321-324 keratin 18 Bos taurus 18-23 19911811-4 2009 The sensor performance for CA15-3 detection was first characterized in phosphate-buffered saline (PBS) buffer and in fetal calf serum. pbs 98-101 mucin 1, cell surface associated Homo sapiens 27-33 19911811-6 2009 It was found that the OFRR was capable of detecting approximately 1 unit/mL CA15-3 in both PBS buffer and diluted serum within approximately 30 min. pbs 91-94 mucin 1, cell surface associated Homo sapiens 76-82 19603006-5 2009 CXCR4 + RED group also significantly prevented bone loss compared to OVX + PBS group (2.7% versus -6.2%, P < 0.05). pbs 75-78 chemokine (C-X-C motif) receptor 4 Mus musculus 0-5 19825938-7 2009 Simultaneous knockdown of dynein and kinesin reverted the effect of single knockdowns on both SGs and PBs, suggesting that a balance between opposing movements driven by these molecular motors governs foci formation and dissolution. pbs 102-105 Dynein heavy chain 64C Drosophila melanogaster 26-32 19825938-7 2009 Simultaneous knockdown of dynein and kinesin reverted the effect of single knockdowns on both SGs and PBs, suggesting that a balance between opposing movements driven by these molecular motors governs foci formation and dissolution. pbs 102-105 Kinesin light chain Drosophila melanogaster 37-44 19837760-8 2009 RESULTS: The treatment of mice with trastuzumab, compared with control mice treated with PBS, resulted in a significant decrease in tumor uptake of (18)F-FDG in HER2-overexpressing MDA-MB-361 xenografts after 16 d of treatment (2.6 +/- 0.8 %ID/g vs. 4.6 +/- 1.8 %ID/g, respectively; P < 0.03) but not after 2 or 9 d of treatment (P = 0.28-0.32). pbs 89-92 erb-b2 receptor tyrosine kinase 2 Mus musculus 161-165 19801846-5 2009 In rounded cells on TNX, phosphorylation of focal adhesion kinase (FAK) was diminished compared with that in cells on control phosphate buffered saline (PBS). pbs 153-156 tenascin XB Mus musculus 20-23 19353525-9 2009 Treatment with Akt-MSCs spared phosphocreatine stores and significantly limited the increase in 2-DG uptake in the residual intact myocardium compared with the PBS- or the MSC-treated animals. pbs 160-163 AKT serine/threonine kinase 1 Rattus norvegicus 15-18 19705882-4 2009 The nanogels were gradually degraded within days in a phosphate buffer solution (PBS) at 37 degrees C. Temperature-responsive biodegradable nanogel systems consisting of biocompatible PEG may have potential utility for high biocompatibility temperature-responsive nanodevices such as microreactor systems, molecular-chaperones, and drug delivery vehicles. pbs 81-84 progestagen associated endometrial protein Homo sapiens 184-187 19616817-1 2009 During tRNA(Lys3) annealing in HIV-1, tRNA(Lys3) binds to both the primer binding site (PBS) and to an 8 nucleotide base-paired sequence upstream of the PBS known as the primer activation signal (PAS). pbs 88-91 mitochondrially encoded tRNA glycine Homo sapiens 7-16 19616817-1 2009 During tRNA(Lys3) annealing in HIV-1, tRNA(Lys3) binds to both the primer binding site (PBS) and to an 8 nucleotide base-paired sequence upstream of the PBS known as the primer activation signal (PAS). pbs 88-91 mitochondrially encoded tRNA glycine Homo sapiens 38-47 19616817-1 2009 During tRNA(Lys3) annealing in HIV-1, tRNA(Lys3) binds to both the primer binding site (PBS) and to an 8 nucleotide base-paired sequence upstream of the PBS known as the primer activation signal (PAS). pbs 153-156 mitochondrially encoded tRNA glycine Homo sapiens 7-16 19616817-1 2009 During tRNA(Lys3) annealing in HIV-1, tRNA(Lys3) binds to both the primer binding site (PBS) and to an 8 nucleotide base-paired sequence upstream of the PBS known as the primer activation signal (PAS). pbs 153-156 mitochondrially encoded tRNA glycine Homo sapiens 38-47 19458189-4 2009 In the present study, we show that heat-shock protein (Hsp) 90 activity is required for efficient targeting of hAgo2 to PBs and SGs. pbs 120-123 heat shock protein 90 alpha family class A member 1 Homo sapiens 35-62 19458189-4 2009 In the present study, we show that heat-shock protein (Hsp) 90 activity is required for efficient targeting of hAgo2 to PBs and SGs. pbs 120-123 argonaute RISC catalytic component 2 Homo sapiens 111-116 19630844-8 2009 CONCLUSIONS AND IMPLICATIONS: The reduction in the both prescription counts and DDD/1,000/day observed for combination asthma medicines, PPIs and statins, which all remained above co-payment thresholds, suggests the increase in PBS co-payments has affected utilisation of these subsidised medicines. pbs 228-231 keratin 5 Homo sapiens 80-85 19136695-7 2009 RESULTS: Toxin-mediated lysis of erythrocytes was inhibited up to 16,000-fold in the presence of CD-cholesterol compared with CD or PBS. pbs 132-135 AT695_RS01930 Staphylococcus aureus 9-14 19616817-7 2009 This suggests that in addition to facilitating annealing of tRNA(Lys3) to the PBS and possible denaturation of the PAS, other functions of NCp7 involved in annealing are required. pbs 78-81 mitochondrially encoded tRNA glycine Homo sapiens 60-69 19760898-5 2009 Repeated PBs and kindling both induced large potentiation of the CA1 basal dendritic synapse, but only hippocampal kindling disrupted the retention of spatial task on the radial arm maze. pbs 9-12 carbonic anhydrase 1 Homo sapiens 65-68 19617342-10 2009 There was also a 2-fold decreased tumor uptake in trastuzumab- versus PBS-treated mice by image volume-of-interest analysis (P = 0.05), suggesting trastuzumab-mediated HER2 downregulation. pbs 70-73 erb-b2 receptor tyrosine kinase 2 Mus musculus 168-172 19394899-4 2009 Cyclic voltammetric results showed that a pair of well-defined quasi-reversible redox peaks appeared in the pH 7.0 phosphate buffer solution (PBS), which was attributed to the direct electron transfer of Mb heme Fe(III)/Fe(II) redox couples with the modified electrode. pbs 142-145 myoglobin Homo sapiens 204-206 18947194-7 2008 With the optimal fabrication parameters, the detection limit for IL-5 was 10 fg/mL in phosphate buffered saline (PBS) and 1 pg/mL in 1% human serum with good specificity and a dynamic range of 3 orders of magnitude. pbs 113-116 interleukin 5 Homo sapiens 65-69 18611437-6 2008 Thus, in the LS, a separate population of neurons is covered by VGLUT3-ir PBs. pbs 74-77 solute carrier family 17 member 8 Homo sapiens 64-70 18823773-3 2009 Experimentally, this fiber-optic biosensor is able to detect AFP concentration in phosphate buffered saline (PBS) solution from 0.1ng/mL to 100ng/mL whereas the linear relationship between the AFP concentrations and the fluorescence signals is shown. pbs 109-112 alpha fetoprotein Homo sapiens 61-64 18823773-3 2009 Experimentally, this fiber-optic biosensor is able to detect AFP concentration in phosphate buffered saline (PBS) solution from 0.1ng/mL to 100ng/mL whereas the linear relationship between the AFP concentrations and the fluorescence signals is shown. pbs 109-112 alpha fetoprotein Homo sapiens 193-196 19105718-11 2009 By tailoring the PPO block length and the number of polymer chains on the surface, flocculation of the magnetite complexes in PBS was avoided. pbs 126-129 protoporphyrinogen oxidase Homo sapiens 17-20 19144318-4 2009 Here, we show that transforming growth factor beta1 (TGFbeta1) and interleukin 21 (IL-21), produced by follicular helper T cells (Tfh), synergized to generate abundant IgA-plasmablasts (PBs). pbs 186-189 transforming growth factor beta 1 Homo sapiens 19-51 19144318-4 2009 Here, we show that transforming growth factor beta1 (TGFbeta1) and interleukin 21 (IL-21), produced by follicular helper T cells (Tfh), synergized to generate abundant IgA-plasmablasts (PBs). pbs 186-189 transforming growth factor beta 1 Homo sapiens 53-61 19144318-4 2009 Here, we show that transforming growth factor beta1 (TGFbeta1) and interleukin 21 (IL-21), produced by follicular helper T cells (Tfh), synergized to generate abundant IgA-plasmablasts (PBs). pbs 186-189 interleukin 21 Homo sapiens 67-81 19144318-4 2009 Here, we show that transforming growth factor beta1 (TGFbeta1) and interleukin 21 (IL-21), produced by follicular helper T cells (Tfh), synergized to generate abundant IgA-plasmablasts (PBs). pbs 186-189 interleukin 21 Homo sapiens 83-88 19144318-4 2009 Here, we show that transforming growth factor beta1 (TGFbeta1) and interleukin 21 (IL-21), produced by follicular helper T cells (Tfh), synergized to generate abundant IgA-plasmablasts (PBs). pbs 186-189 CD79a molecule Homo sapiens 168-171 19144318-7 2009 This was supported by the presence of CCR10(+)IgA(+)PBs in tonsil GCs. pbs 52-55 C-C motif chemokine receptor 10 Homo sapiens 38-43 19144318-7 2009 This was supported by the presence of CCR10(+)IgA(+)PBs in tonsil GCs. pbs 52-55 CD79a molecule Homo sapiens 46-49 19082426-1 2008 To test the hypothesis that exogenous purified angiotensin II (ANG) might cause apoptosis of alveolar epithelial cells (AECs) and acute lung injury, male Wistar rats were intratracheally instilled with purified ANG (10 mumol/L), ANG plus the caspase inhibitor ZVAD-fmk (60 mumol/L), ANG plus the ANG receptor AT1 antagonist losartan (LOS, 100 mumol/L) or sterile phosphate-buffered saline (PBS) vehicle alone. pbs 390-393 angiotensinogen Rattus norvegicus 47-61 19082426-3 2008 Terminal deoxynucleotidyl transferase-mediated nick-end labeling (TUNEL) revealed that instillation of ANG, but not PBS alone, increased labeling of fragmented DNA in bronchiolar epithelial cells and in AECs (P<0.05) at 6 h post-ANG. pbs 116-119 angiotensinogen Rattus norvegicus 103-106 18643965-3 2008 We identified PBs and SGs in plant cells by detection of DCP1, DCP2 and XRN4, as marker proteins for the 5"-->3" mRNA degradation pathway, and eIF4E, as well as the RNA binding proteins RBP47 and UBP1, as marker proteins for stored mRNPs in SGs. pbs 14-17 upstream binding protein 1 Homo sapiens 199-203 18779327-6 2008 Furthermore, the complex formed between hMex-3B and Argonaute proteins is excluded from PBs when the interaction with 14-3-3 is disrupted, whereas the recruitment to SG is not affected. pbs 88-91 mex-3 RNA binding family member B Homo sapiens 40-47 18643965-3 2008 We identified PBs and SGs in plant cells by detection of DCP1, DCP2 and XRN4, as marker proteins for the 5"-->3" mRNA degradation pathway, and eIF4E, as well as the RNA binding proteins RBP47 and UBP1, as marker proteins for stored mRNPs in SGs. pbs 14-17 decapping mRNA 1B Homo sapiens 57-61 18572413-11 2008 Tissue endothelin-1 levels were significantly reduced (6.29+/-1.90 pg/100mg PBS, 3.55+/-1.15 pg/100mg DXS p=0.030) as well as thrombin-anti-thrombin formation (20.7+/-1.0 microg/ml PBS, 12.8+/-4.1 microg/ml DXS, p=0.043). pbs 76-79 endothelin-1 Sus scrofa 7-19 18942671-5 2008 RESULTS: Following the January 2005 increase in PBS co-payments, significant decrease in dispensing volumes were observed in 12 of the 17 medicine categories (range: 3.2-10.9%), namely anti-epileptics, anti-Parkinson"s treatments, combination asthma medicines, eye-drops, glaucoma treatments, HmgCoA reductase inhibitors, insulin, muscle relaxants, non-aspirin antiplatelets, osteoporosis treatments, proton-pump inhibitors (PPIs) and thyroxine. pbs 48-51 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens 293-309 18942671-5 2008 RESULTS: Following the January 2005 increase in PBS co-payments, significant decrease in dispensing volumes were observed in 12 of the 17 medicine categories (range: 3.2-10.9%), namely anti-epileptics, anti-Parkinson"s treatments, combination asthma medicines, eye-drops, glaucoma treatments, HmgCoA reductase inhibitors, insulin, muscle relaxants, non-aspirin antiplatelets, osteoporosis treatments, proton-pump inhibitors (PPIs) and thyroxine. pbs 48-51 insulin Homo sapiens 322-329 18572413-11 2008 Tissue endothelin-1 levels were significantly reduced (6.29+/-1.90 pg/100mg PBS, 3.55+/-1.15 pg/100mg DXS p=0.030) as well as thrombin-anti-thrombin formation (20.7+/-1.0 microg/ml PBS, 12.8+/-4.1 microg/ml DXS, p=0.043). pbs 181-184 endothelin-1 Sus scrofa 7-19 19087701-14 2008 (3) The serum IFN-alpha levels of the alpha-Fodrin and submaxillary gland homogenate groups were (81.6 +/- 7.1) and (90.5 +/- 4.9) pg/ml respectively, both significantly higher than those of the GST and PBS groups [(30.1 +/- 5.9) and (19.3 +/- 6.4) pg/ml respectively, both P < 0.05]. pbs 203-206 interferon alpha Mus musculus 14-23 18590911-1 2008 Using a quartz crystal resonator system operating at 5 MHz the shear wave propagating properties of bovine serum albumin (BSA) have been monitored as it is adsorbed on a gold surface from a phosphate buffered saline (PBS) solution. pbs 217-220 albumin Homo sapiens 107-120 19087701-15 2008 The serum IL-2 levels of the alpha-Fodrin and submaxillary gland homogenate groups were (18.7 +/- 2.3) and (19.8 +/- 0.9) pg/ml respectively, both significantly higher than those of the GST and PBS groups [(4.9 +/- 1.1) and (3.5 +/- 1.6) pg/ml respectively, both P < 0.05]. pbs 194-197 interleukin 2 Mus musculus 10-14 19080481-8 2008 RESULTS: 17, 24, and 31 days after the immunization, the RGC density of the Cop-1 Group were (2617 +/- 17)/mm(2), (2588 +/- 206)/mm(2), and (2394 +/- 15)/mm(2) respectively, all significantly higher than those of the PBS Group [(2357 +/- 37)/mm(2), (2277 +/- 340)/mm(2), and (2129 +/- 17)/mm(2) respectively, all P < 0.05]. pbs 217-220 COP1, E3 ubiquitin ligase Rattus norvegicus 76-81 18643965-3 2008 We identified PBs and SGs in plant cells by detection of DCP1, DCP2 and XRN4, as marker proteins for the 5"-->3" mRNA degradation pathway, and eIF4E, as well as the RNA binding proteins RBP47 and UBP1, as marker proteins for stored mRNPs in SGs. pbs 14-17 decapping mRNA 2 Homo sapiens 63-67 19080481-9 2008 10, 17, 24, and 31 days after the immunization the numbers of T cells in the retina of Cop-1 Group were (11.3 +/- 2.8)/mm(2), (36.7 +/- 5.2)/mm(2), (33.9 +/- 3.0)/mm(2), and (21.4 +/- 5.9)/mm(2), all significantly higher than those of PBS Group (4.7 +/- 3.6)/mm(2), (19.7 +/- 2.4)/mm(2), (15.3 +/- 4.0)/mm(2), and (13.3 +/- 4.4)/mm(2) respectively, all P < 0.01). pbs 235-238 COP1, E3 ubiquitin ligase Rattus norvegicus 87-92 18509865-3 2008 RESULTS: We have shown a significant decrease in claudin-5 mRNA levels 24 and 48 hours post-delivery of siRNA, with levels of protein expression decreasing up to 48 hours post-injection compared to uninjected, phosphate-buffered saline (PBS)-injected and non-targeting siRNA-injected mice. pbs 237-240 claudin 5 Mus musculus 49-58 18067924-7 2008 Echocardiographic analysis at 4 wk post-MI to assess left ventricular (LV) function revealed that LV ejection fraction was increased in the HGF treated group compared with the phosphate-buffered saline (PBS) control group. pbs 203-206 hepatocyte growth factor Rattus norvegicus 140-143 18067924-8 2008 Likewise, LV end diastolic dimension was reduced in the HGF treated group compared with the PBS control group. pbs 92-95 hepatocyte growth factor Rattus norvegicus 56-59 18067924-9 2008 Similarly, invasive hemodynamics at 12 wk showed improved contractility and relaxation in the HGF treated group compared with the PBS control group. pbs 130-133 hepatocyte growth factor Rattus norvegicus 94-97 18067924-12 2008 IFS was decreased 4.2-fold in the HGF treated group compared with the PBS control group. pbs 70-73 hepatocyte growth factor Rattus norvegicus 34-37 18714441-6 2008 RESULTS: Hepatitis E virus isolates in albumin solutions were inactivated slowly at 60 degrees C for 5 h and the resultant log reduction factor (LRF) was from 1.0 to > or = 2.2, whereas the virus in PBS was inactivated quickly to below the detection limit and the LRF was > or = 2.4 to > or = 3.7. pbs 202-205 CREB3 regulatory factor Homo sapiens 145-148 18568516-6 2008 RESULTS: Concentrations of MIF in the endotoxin group at 1 day and 3 days were significantly higher than in the PBS control group. pbs 112-115 macrophage migration inhibitory factor (glycosylation-inhibiting factor) Mus musculus 27-30 18410469-8 2008 METHOD OF STUDY: Pharmaceutical grade bioactive TGF-beta3 with a bovine serum albumin (BSA) carrier 0.1-1% in phosphate-buffered saline (PBS) was given into the vaginal tract of CBA/J female mice at the time of mating with DBA/2 males. pbs 137-140 transforming growth factor, beta 3 Mus musculus 48-57 18410469-11 2008 RESULTS: Two nanogram of intravaginal TGF-beta3 in 0.1% BSA-PBS or 20 ng in 1% BSA-PBS reduced abortion rates. pbs 60-63 transforming growth factor, beta 3 Mus musculus 38-47 18410469-11 2008 RESULTS: Two nanogram of intravaginal TGF-beta3 in 0.1% BSA-PBS or 20 ng in 1% BSA-PBS reduced abortion rates. pbs 83-86 transforming growth factor, beta 3 Mus musculus 38-47