PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 19198839-0 2009 Inhibition of drug metabolizing cytochrome P450s by the aromatase inhibitor drug letrozole and its major oxidative metabolite 4,4"-methanol-bisbenzonitrile in vitro. 4,4'-methanol-bisbenzonitrile 126-155 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 32-47 19198839-1 2009 PURPOSE: To determine the inhibitory potency of letrozole and its main human metabolite, 4,4"-methanol-bisbenzonitrile, on the activities of eight cytochrome P450 (CYP) enzymes. 4,4'-methanol-bisbenzonitrile 89-118 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 147-162 19198839-1 2009 PURPOSE: To determine the inhibitory potency of letrozole and its main human metabolite, 4,4"-methanol-bisbenzonitrile, on the activities of eight cytochrome P450 (CYP) enzymes. 4,4'-methanol-bisbenzonitrile 89-118 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 164-167