PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
21954340-7	2011	Further investigation of these processes revealed that 2-BP directly promotes ROS generation, loss of mitochondrial membrane potential (MMP), and activation of caspase-3, whereas resveratrol effectively blocks 2-BP-induced ROS production and the accompanying apoptotic biochemical changes.	2-bp	55-59	caspase 3	Mus musculus	160-169
20554630-5	2010	2-BP significantly increased the TUNEL-positive cells and the activation of caspase-3 and decreased the genes and proteins expression of Bax, Bcl-2 and p53.	2-bp	0-4	caspase 3	Rattus norvegicus	76-85
20554630-5	2010	2-BP significantly increased the TUNEL-positive cells and the activation of caspase-3 and decreased the genes and proteins expression of Bax, Bcl-2 and p53.	2-bp	0-4	BCL2 associated X, apoptosis regulator	Rattus norvegicus	137-140
20554630-5	2010	2-BP significantly increased the TUNEL-positive cells and the activation of caspase-3 and decreased the genes and proteins expression of Bax, Bcl-2 and p53.	2-bp	0-4	BCL2, apoptosis regulator	Rattus norvegicus	142-147
20554630-5	2010	2-BP significantly increased the TUNEL-positive cells and the activation of caspase-3 and decreased the genes and proteins expression of Bax, Bcl-2 and p53.	2-bp	0-4	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	152-155
11437647-0	2001	Involvement of Bcl-2 family genes and Fas signaling system in primary and secondary male germ cell apoptosis induced by 2-bromopropane in rat.	2-bp	120-134	BCL2, apoptosis regulator	Rattus norvegicus	15-20
11437647-9	2001	Downregulation of Bcl-2 after the first or second injection of 2-BP and upregulation of Bax after the first treatment contributed to the initiation of primary apoptosis of spermatogonia.	2-bp	63-67	BCL2, apoptosis regulator	Rattus norvegicus	18-23
11437647-12	2001	Our results indicate that 2-BP resulted in apoptotic death of testicular germ cells and that this process involves the Bcl-2 family genes and the Fas signaling system.	2-bp	26-30	BCL2, apoptosis regulator	Rattus norvegicus	119-124