7172416-4 1982 It is concluded that 9-OHE may also act as an inducer of the hepatic microsomal mixed function oxidases, selectively inducing the synthesis of cytochrome P-448. 9-hydroxyellipticine 21-26 cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus 143-159 7285236-3 1981 9-Hydroxyellipticine (9-OHE) interacts with human liver cytochrome P-450 exhibiting a type II spectrum (lambda max: 428 nm, Ks = 1.1 microM). 9-hydroxyellipticine 0-20 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 56-72 7285236-3 1981 9-Hydroxyellipticine (9-OHE) interacts with human liver cytochrome P-450 exhibiting a type II spectrum (lambda max: 428 nm, Ks = 1.1 microM). 9-hydroxyellipticine 22-27 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 56-72 7428105-0 1980 Inhibition of cytochrome P-448 mixed function oxidase activity following administration of 9-hydroxyellipticine to rats. 9-hydroxyellipticine 91-111 cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus 14-30 7428105-1 1980 The in vitro inhibitor of mixed-function oxidation, 9-hydroxyellipticine, non-competitively inhibited the binding of the type II substrate, aniline, to cytochrome P-448 of hepatic microsomal preparations from rats pretreated with 3-methylcholanthrene. 9-hydroxyellipticine 52-72 cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus 152-168 7428105-3 1980 Following the pretreatment of rats intraperitoneally with 9-hydroxyellipticine and phenobarbitone, the cytochrome P-448-specific enzyme activity, ethoxyresorufin O-deethylase, was 50% inhibited in vitro but cytochrome P-450, cytochrome P-450 reductase, and other mixed function oxidase activities were unaffected. 9-hydroxyellipticine 58-78 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 207-251 7428105-4 1980 With rats pretreated with 9-hydroxyellipticine and 3-methylcholanthrene, inhibition of ethoxyresorufin O-deethylase was 90%, and cytochrome P-450/P-448, cytochrome P-450 reductase, biphenyl 2- and 4-hydroxylase were inhibited by 30, 15, 50 and 40% respectively. 9-hydroxyellipticine 26-46 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 129-145 7428105-4 1980 With rats pretreated with 9-hydroxyellipticine and 3-methylcholanthrene, inhibition of ethoxyresorufin O-deethylase was 90%, and cytochrome P-450/P-448, cytochrome P-450 reductase, biphenyl 2- and 4-hydroxylase were inhibited by 30, 15, 50 and 40% respectively. 9-hydroxyellipticine 26-46 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 153-169 7428105-5 1980 It is concluded that 9-hydroxyellipticine administered in vivo markedly inhibits mixed-function oxidations which are specific to cytochrome P-448, but has no effect on cytochrome P-450-catalysed microsomal oxidation. 9-hydroxyellipticine 21-41 cytochrome P450, family 1, subfamily a, polypeptide 2 Rattus norvegicus 129-145 498356-0 1979 Interaction of 9-hydroxyellipticine with two forms of partially purified rabbit lung cytochrome P-450. 9-hydroxyellipticine 15-35 cytochrome P-450 Oryctolagus cuniculus 85-101