PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
25974050-7	2015	The reactions involving the OH radical are predicted to have the highest rates among the five abstracting radicals, while those initiated by HO2 are expected to be the lowest.	oh radical	28-38	heme oxygenase 2	Homo sapiens	141-144
26021696-6	2015	These results suggest that VOSO4-induced  OH radical, which is a signaling species, promotes glucose uptake via the IR/Akt signaling pathway.	oh radical	42-52	insulin receptor	Homo sapiens	116-118
26021696-6	2015	These results suggest that VOSO4-induced  OH radical, which is a signaling species, promotes glucose uptake via the IR/Akt signaling pathway.	oh radical	42-52	AKT serine/threonine kinase 1	Homo sapiens	119-122
25965106-1	2015	High level coupled-cluster theory, with spin-orbit coupling evaluated via the Breit-Pauli operator in the interacting-states approach, is used to investigate the OH radical reaction with Cl2 and the subsequent reaction HOCl + Cl.	oh radical	162-172	endogenous retrovirus group W member 5	Homo sapiens	187-190
25207959-1	2014	The X-abstraction (X = H, I) pathways in the reaction of CHI3 with OH radical, a possible iodoform removal process relevant to the Earth"s atmosphere and conditions prevailing in the case of a nuclear accident, have been studied applying highly correlated ab initio quantum chemistry methods and canonical transition-state theory to obtain reaction energy profiles and rate constants.	oh radical	67-77	chitinase 1	Homo sapiens	57-61
25854242-7	2015	This interpretation is motivated by the separation between the Q(3/2) and R(3/2) transitions in the infrared spectrum of the helium-solvated (2)Pi3/2 OH radical.	oh radical	150-160	peptidase inhibitor 3	Homo sapiens	144-149
25207959-5	2014	The overall rate constant at 298 K based on our ab initio calculations is 4.90 x 10(-11) cm(3) molecule(-1) s(-1), with the I-abstraction pathway being the major channel over the temperature range of 250-2000 K. The CHI3 atmospheric lifetime with respect to the removal reaction with OH radical is predicted to be about 6 h, very short compared to that of other halomethanes.	oh radical	284-294	chitinase 1	Homo sapiens	216-220
25781275-7	2014	However, SPL had the highest DPPH, H2O2 and OH radical scavenging abilitie, while the reducing power of the extracts followed the order SPR > SPL > SPS at 1000 microg/ml.	oh radical	44-54	sphingosine-1-phosphate lyase 1	Rattus norvegicus	9-12
25324649-13	2014	These novel results demonstrate that  OH radical-mediated changes in SOD present unique neo-epitopes that might contribute to antigen-driven antibody induction in AA.	oh radical	38-48	superoxide dismutase 1	Homo sapiens	69-72
23354476-1	2013	Theoretical investigations are carried out on reaction mechanism of the reactions of CF3CH2NH2 (TFEA) with the OH radical by means of ab initio and DFT methods.	oh radical	111-121	transcription factor binding to IGHM enhancer 3	Homo sapiens	96-100
24410212-5	2014	The torsional barrier of the methyl top is fairly large in syn-CH3CHOO, implying a significant interaction between the terminal oxygen and the protons of the methyl moiety, which may be responsible for the high production yields of the OH radical from energized alkyl-substituted Criegee intermediates.	oh radical	236-246	synemin	Homo sapiens	59-62
23414832-2	2013	Dihydroxybenzoic acid (DHBA) concentration as index of OH radical generation was 13 and 115 muM at 10 min in the sonocatalytic reaction and Fenton reaction, respectively.	oh radical	55-65	latexin	Homo sapiens	92-95
23656398-3	2013	In the present study, the reaction of OH radical with dimethylphenol isomers is studied using density functional theory methods, B3LYP, M06-2X, and MPW1K, and also at the MP2 level of theory using 6-31G(d,p) and 6-31+G(d,p) basis sets.	oh radical	38-48	tryptase pseudogene 1	Homo sapiens	171-174
20827960-0	2010	[LIF spectroscopic study of OH radical].	oh radical	28-38	LIF interleukin 6 family cytokine	Homo sapiens	1-4
22562169-1	2012	The mechanism, kinetics and thermochemistry of the gas-phase reactions between CHF(2)OCHF(2) (HFE-134) and OH radical are investigated using the high level ab initio G2(MP2) and hybrid density functional model MPWB1K quantum chemical methods.	oh radical	107-117	tryptase pseudogene 1	Homo sapiens	169-172
22652964-8	2012	APCPP-gamma-S proved to be more efficient than ascorbic acid and GSH in reducing OH radical production in Fe(2+)/H(2)O(2) system (IC(50) values 85, 216 and, 92 muM, respectively).	oh radical	81-91	latexin	Homo sapiens	160-163
21879770-1	2011	Rate coefficients, k, for the gas-phase reaction of the OH radical with (Z)-CF(3)CH CHCF(3) (cis-1,1,1,4,4,4-hexafluoro-2-butene) were measured under pseudo-first-order conditions in OH using pulsed laser photolysis (PLP) to produce OH and laser-induced fluorescence (LIF) to detect it.	oh radical	56-66	proteolipid protein 1	Homo sapiens	217-220
21879770-1	2011	Rate coefficients, k, for the gas-phase reaction of the OH radical with (Z)-CF(3)CH CHCF(3) (cis-1,1,1,4,4,4-hexafluoro-2-butene) were measured under pseudo-first-order conditions in OH using pulsed laser photolysis (PLP) to produce OH and laser-induced fluorescence (LIF) to detect it.	oh radical	56-66	LIF interleukin 6 family cytokine	Homo sapiens	268-271
21879770-5	2011	OH radical rate coefficients were also measured at 296, 345, and 375 K using a relative rate technique and found to be in good agreement with the PLP-LIF results.	oh radical	0-10	proteolipid protein 1	Homo sapiens	146-149
21879770-5	2011	OH radical rate coefficients were also measured at 296, 345, and 375 K using a relative rate technique and found to be in good agreement with the PLP-LIF results.	oh radical	0-10	LIF interleukin 6 family cytokine	Homo sapiens	150-153
22411110-1	2012	Several possible mechanisms underlying isoguanine formation when OH radical attacks the C(2) position of adenine (A C 2) are investigated theoretically for the first time.	oh radical	65-75	adenylate cyclase 2	Homo sapiens	114-119
23216635-9	2012	Catalase inhibited  OH generation, indicating that H(2)O(2) was generated from cells stimulated by Cr(VI) and that H(2)O(2) functioned as a precursor of  OH radical generation.	oh radical	154-164	catalase	Homo sapiens	0-8
20853389-0	2010	Kinetic study of OH radical reactions with CF3CCl=CCl2, CF3CCl=CClCF3 and CF3CF=CFCF3.	oh radical	17-27	C-C motif chemokine ligand 2	Homo sapiens	50-54
20225809-1	2010	Rate coefficients, k, for the gas-phase reaction of the OH radical with CH(2)=CHF (k(1)) and CH(2)=CF(2) (k(2)) were measured under pseudo-first-order conditions in OH using pulsed laser photolysis to produce OH and laser-induced fluorescence (PLP-LIF) to detect it.	oh radical	56-66	proteolipid protein 1	Homo sapiens	244-247
20345179-5	2010	From a comparison of the chamber reaction product profiles with ambient air samples, the ratios of 2-methyl-4-nitronaphthalene/1-methyl-5-nitronaphthalene and of 2,7DM4NN/1,7DM5NN are proposed to be sensitive markers of nitroarene formation from NO3 versus OH radical chemistry.	oh radical	257-267	NBL1, DAN family BMP antagonist	Homo sapiens	246-249
20225809-1	2010	Rate coefficients, k, for the gas-phase reaction of the OH radical with CH(2)=CHF (k(1)) and CH(2)=CF(2) (k(2)) were measured under pseudo-first-order conditions in OH using pulsed laser photolysis to produce OH and laser-induced fluorescence (PLP-LIF) to detect it.	oh radical	56-66	LIF interleukin 6 family cytokine	Homo sapiens	248-251
16834202-1	2005	The hydrogen abstraction reaction of the OH radical with CH(3)CHF(2) (HFC152-a) has been studied theoretically over a wide temperature range, 200-3000 K. Two different reactive sites of the molecule, CH(3) and CHF(2) groups have been investigated precisely, and results confirm that CHF(2) position of the molecule is a highly reactive site.	oh radical	41-51	hes related family bHLH transcription factor with YRPW motif 1	Homo sapiens	62-67
19162521-4	2009	It was found that the degradation of the dye was accelerated with increased concentrations of CCl(4) via the accumulation of reactive chlorine species and the hindrance of OH radical combination reactions with atomic hydrogen.	oh radical	172-182	C-C motif chemokine ligand 4	Homo sapiens	94-100
17719074-6	2008	Ozonation at high pH and O(3)/H(2)O(2) AOP will be highly efficient for the treatment of all chemicals in this study except RDX, which shows the lowest OH radical reactivity.	oh radical	152-162	radixin	Homo sapiens	124-127
17506535-0	2007	Mechanism of OH radical reactions with HCN and CH3CN: OH regeneration in the presence of O2.	oh radical	13-23	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	39-42
16846707-5	2006	The extract also inhibited OH radical induced oxidation of protein (BSA) and LPO in murine hepatic microsomes.	oh radical	27-37	lactoperoxidase	Mus musculus	77-80
16846707-6	2006	The determination of metal chelating capacity of the extract indicated chelating of metal ions (Fe2+) to be a putative mechanism implicated in the inhibition of OH radical-induced BSA oxidation and LPO.	oh radical	161-171	lactoperoxidase	Mus musculus	198-201
16526636-0	2006	Kinetics of OH radical reaction with anthracene and anthracene-d10.	oh radical	12-22	CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion	Homo sapiens	63-66
19950919-1	2010	A dual-level direct dynamic method is employed to study the reaction mechanisms of CF(3)CHFOCF(3) (HFE-227 mc) with the OH radical and Cl atom.	oh radical	120-130	homeostatic iron regulator	Homo sapiens	99-102
18780357-8	2009	In addition, the mechanisms of subsequent reactions of product radicals and OH radical are further investigated at the G3(MP2)//B3LYP/6-311G(d,p) level, and the main products are predicted in the this article.	oh radical	76-86	tryptase pseudogene 1	Homo sapiens	122-125
18780357-8	2009	In addition, the mechanisms of subsequent reactions of product radicals and OH radical are further investigated at the G3(MP2)//B3LYP/6-311G(d,p) level, and the main products are predicted in the this article.	oh radical	76-86	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	130-133
18986671-1	2008	Biodegradable organic carbon (BDOC) from OH radical oxidation (UV-H2O2) of the recalcitrant industrial anti-foaming agents and flame retardants, tri-n-butyl phosphate (TBP) and tris(2-chloroethyl) phosphate (TCEP), was quantified with respect to the fraction of the TBP or TCEP photooxidized.	oh radical	41-51	TATA-box binding protein	Homo sapiens	168-171
18986671-1	2008	Biodegradable organic carbon (BDOC) from OH radical oxidation (UV-H2O2) of the recalcitrant industrial anti-foaming agents and flame retardants, tri-n-butyl phosphate (TBP) and tris(2-chloroethyl) phosphate (TCEP), was quantified with respect to the fraction of the TBP or TCEP photooxidized.	oh radical	41-51	TATA-box binding protein	Homo sapiens	266-269
16834202-1	2005	The hydrogen abstraction reaction of the OH radical with CH(3)CHF(2) (HFC152-a) has been studied theoretically over a wide temperature range, 200-3000 K. Two different reactive sites of the molecule, CH(3) and CHF(2) groups have been investigated precisely, and results confirm that CHF(2) position of the molecule is a highly reactive site.	oh radical	41-51	hes related family bHLH transcription factor with YRPW motif 1	Homo sapiens	210-215
16834202-1	2005	The hydrogen abstraction reaction of the OH radical with CH(3)CHF(2) (HFC152-a) has been studied theoretically over a wide temperature range, 200-3000 K. Two different reactive sites of the molecule, CH(3) and CHF(2) groups have been investigated precisely, and results confirm that CHF(2) position of the molecule is a highly reactive site.	oh radical	41-51	hes related family bHLH transcription factor with YRPW motif 1	Homo sapiens	210-215
21782712-7	2004	Interestingly, when the cells were exposed to 100mU/ml GO for 4h, the DNA-binding activity of nuclear factor-kappa B (NF-kappaB) was increased 4.15-fold (P<0.01) compared to the control, whereas 40mug/ml SNL glycoprotein completely blocked the DNA-binding activity of OH radical-induced NF-kappaB by electrophoretic mobility shift assays (EMSAs).	oh radical	271-281	nuclear factor kappa B subunit 1	Homo sapiens	94-116
21782712-7	2004	Interestingly, when the cells were exposed to 100mU/ml GO for 4h, the DNA-binding activity of nuclear factor-kappa B (NF-kappaB) was increased 4.15-fold (P<0.01) compared to the control, whereas 40mug/ml SNL glycoprotein completely blocked the DNA-binding activity of OH radical-induced NF-kappaB by electrophoretic mobility shift assays (EMSAs).	oh radical	271-281	nuclear factor kappa B subunit 1	Homo sapiens	118-127
12384526-4	2002	The scavenging of UV-generated H(2)O(2) by N-acety-L-cyteine (a general antioxidant) or catalase (a specific H(2)O(2) scavenger) inhibited p70(S6k) phosphorylation at Thr(389) and Thr(421)/Ser(424), whereas pretreatment of cells with sodium formate (an.OH radical scavenger) or superoxide dismutase (an O( minus sign, dot below )(2) radical scavenger) did not show any inhibitory effects.	oh radical	253-263	ubiquitin associated and SH3 domain containing B	Homo sapiens	139-142
10942736-13	2000	NADPH, which accelerated the one-electron reduction of Cr(VI) to Cr(V) and increased.OH radical generation, dramatically enhanced p53 activation.	oh radical	85-95	tumor protein p53	Homo sapiens	130-133
10942736-14	2000	Thus.OH radical generated from Cr(VI) reduction in A549 cells is responsible for Cr(VI)-induced p53 activation.	oh radical	5-15	tumor protein p53	Homo sapiens	96-99
10909729-2	2000	The rate of OH radical formation from water is 19.8 microM min-1 under argon and 14.7 microM min-1 under air in the same sonolysis conditions.	oh radical	12-22	CD59 molecule (CD59 blood group)	Homo sapiens	59-64
10909729-2	2000	The rate of OH radical formation from water is 19.8 microM min-1 under argon and 14.7 microM min-1 under air in the same sonolysis conditions.	oh radical	12-22	CD59 molecule (CD59 blood group)	Homo sapiens	93-98
26368635-11	2000	Activation of AP-1 by asbestos or silica was inhibited in both in vitro and in vivo systems by aspirin, which exhibits OH radical scavenging properties.	oh radical	119-129	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	14-18
10929380-5	2000	The rate coefficients and the efficiencies of the .OH radical inducing SSB were deduced.	oh radical	51-61	small RNA binding exonuclease protection factor La	Homo sapiens	71-74
2722888-1	1989	The interaction between superoxide dismutase (SOD) and peroxide, under anaerobic conditions in the presence of an OH radical scavenger, formate, and an indicator, nitro blue tetrazolium, involves five reactions and an equilibrium: (table; see text) Reaction 3 occurs at a rate that is proportional to both peroxide and enzyme with no kinetic evidence for any intermediate peroxide-enzyme complex.	oh radical	114-124	superoxide dismutase 1	Homo sapiens	24-44
10391125-18	1999	Antioxidants, which scavenge *OH radical or its precursors, inhibit NF-kappaB activation.	oh radical	30-40	nuclear factor kappa B subunit 1	Homo sapiens	68-77
8244994-3	1993	In lipopolysaccharide-stimulated human whole blood, the OH radical scavenger dimethyl sulfoxide (Me2SO) dramatically inhibited (approximately 90%) IL-8 production, but had minimal effects on the production of tumor necrosis factor, interleukin 1 beta (IL-1), and IL-6.	oh radical	56-66	C-X-C motif chemokine ligand 8	Homo sapiens	147-151
8244994-3	1993	In lipopolysaccharide-stimulated human whole blood, the OH radical scavenger dimethyl sulfoxide (Me2SO) dramatically inhibited (approximately 90%) IL-8 production, but had minimal effects on the production of tumor necrosis factor, interleukin 1 beta (IL-1), and IL-6.	oh radical	56-66	interleukin 1 beta	Homo sapiens	232-250
8244994-3	1993	In lipopolysaccharide-stimulated human whole blood, the OH radical scavenger dimethyl sulfoxide (Me2SO) dramatically inhibited (approximately 90%) IL-8 production, but had minimal effects on the production of tumor necrosis factor, interleukin 1 beta (IL-1), and IL-6.	oh radical	56-66	interleukin 1 beta	Homo sapiens	252-256
8244994-3	1993	In lipopolysaccharide-stimulated human whole blood, the OH radical scavenger dimethyl sulfoxide (Me2SO) dramatically inhibited (approximately 90%) IL-8 production, but had minimal effects on the production of tumor necrosis factor, interleukin 1 beta (IL-1), and IL-6.	oh radical	56-66	interleukin 6	Homo sapiens	263-267
8216610-1	1993	Both phenylbutazon and mofebutazon inhibit oxidative fragmentation of the methionine derivative, 2-keto-4-methylthio-butyric acid (KMB) by xanthine oxidase--or diaphorase mediated OH radical production.	oh radical	180-190	dihydrolipoamide dehydrogenase	Homo sapiens	160-170
34445313-5	2021	The ortho compounds MnTE-2-PyP5+ (BMX-010, AEOL10113), MnTnBuOE-2-PyP5+ (BMX-001) and MnTnHex-2-PyP5+ are able to redox cycle with ascorbate whereby producing H2O2 which is subsequently coupled with Cu(I) to produce the  OH radical essential for HA degradation.	oh radical	221-231	BMX non-receptor tyrosine kinase	Homo sapiens	73-76
2485127-5	1989	Effects of SOD and catalase as well as pH on the ESR signal of the spin adduct have identified a set of reactions that eventually leads to .OH radical formation by [Cu(PMA)]+.	oh radical	140-150	superoxide dismutase 1	Homo sapiens	11-14
2485127-5	1989	Effects of SOD and catalase as well as pH on the ESR signal of the spin adduct have identified a set of reactions that eventually leads to .OH radical formation by [Cu(PMA)]+.	oh radical	140-150	catalase	Homo sapiens	19-27
10665959-17	2000	The number of ssb saturates at intermediate concentrations of H2O2 suggesting that a limited amount of chromatin-bound metal ions is available for OH radical generation.	oh radical	147-157	lupus La protein	Cricetulus griseus	14-17
12075427-3	2000	Moreover, the rate coefficients and the efficiencies of the.OH radical inducing SSB and alphaDSB were deduced.	oh radical	60-70	small RNA binding exonuclease protection factor La	Homo sapiens	80-83
10402675-13	1999	The results show that Cr(IV) can cause NF-kappa B activation, DNA strand breaks and dG hydroxylation through .OH radical-initiated reactions.	oh radical	110-120	nuclear factor kappa B subunit 1	Homo sapiens	39-49
8978742-5	1997	In the presence of H2O2 and Fe2+, the addition of TH increases the production of the highly reactive.OH radical, probably via a Fenton type of reaction.	oh radical	101-111	tyrosine hydroxylase	Homo sapiens	50-52
8138187-1	1993	In the present study, using the technique of EPR spin trapping with DMPO a spin trap, we demonstrated formation of thiyl radicals from thiol-containing angiotensin converting enzyme (ACE) inhibitor captopril (CAP) and from its stereoisomer epicaptopril (EPICAP), a non-ACE inhibitor, in the process of .OH radical scavenging.	oh radical	303-313	angiotensin I converting enzyme	Homo sapiens	152-181
8138187-1	1993	In the present study, using the technique of EPR spin trapping with DMPO a spin trap, we demonstrated formation of thiyl radicals from thiol-containing angiotensin converting enzyme (ACE) inhibitor captopril (CAP) and from its stereoisomer epicaptopril (EPICAP), a non-ACE inhibitor, in the process of .OH radical scavenging.	oh radical	303-313	angiotensin I converting enzyme	Homo sapiens	183-186
1660479-6	1991	These results indicate that: 1) .OH radical was most likely the ultimate O2 species responsible for DNA damage and activation of poly(ADP)ribose polymerase; 2) both H2O2 and .OH radicals were involved in the other cytotoxic effects (inhibition of protein synthesis and reduction of NAD and ATP stores); and 3) NAD and ATP depletion did not result solely from activation of poly(ADP)ribose polymerase, but other mechanisms are likely to be involved.	oh radical	33-43	poly(ADP-ribose) polymerase 1	Homo sapiens	129-155
1660479-6	1991	These results indicate that: 1) .OH radical was most likely the ultimate O2 species responsible for DNA damage and activation of poly(ADP)ribose polymerase; 2) both H2O2 and .OH radicals were involved in the other cytotoxic effects (inhibition of protein synthesis and reduction of NAD and ATP stores); and 3) NAD and ATP depletion did not result solely from activation of poly(ADP)ribose polymerase, but other mechanisms are likely to be involved.	oh radical	33-43	poly(ADP-ribose) polymerase 1	Homo sapiens	373-399
1847890-4	1991	The results show that caffeine effectively scavenges .OH with a reaction rate constant of approximately 5.9 x 10(9) M-1 sec-1 that is comparable with those of other efficient .OH radical scavengers.	oh radical	176-186	secretory blood group 1, pseudogene	Homo sapiens	120-125
2287636-5	1990	For comparison, the number of ssb per OH radical reacting with dsDNA is 0.22.	oh radical	38-48	small RNA binding exonuclease protection factor La	Bos taurus	30-33
2178178-4	1990	Superoxide dismutase (SOD) causes only a minor effect on the .OH radical and Cr(V) formation, indicating that the O2- is not significantly involved in the reaction mechanism.	oh radical	62-72	superoxide dismutase 1	Homo sapiens	0-20
2178178-4	1990	Superoxide dismutase (SOD) causes only a minor effect on the .OH radical and Cr(V) formation, indicating that the O2- is not significantly involved in the reaction mechanism.	oh radical	62-72	superoxide dismutase 1	Homo sapiens	22-25
1967291-3	1990	At low nucleotide concentrations (0.05 mol dm-3) the spin-trapped radicals produced by sonolysis are due to H atom and OH radical reactions, typically addition to the 5,6 double bond of the base moiety.	oh radical	119-129	spindlin 1	Homo sapiens	53-57
21898467-1	2011	A beta-hairpin peptide (PDB ID 1UAO) was modeled to explore the backbone oxidation of a protein by an OH radical to abstract one alpha-H atom with ab initio calculation at the B3LYB/6-31G(d) without any constraint.	oh radical	102-112	amyloid beta precursor protein	Homo sapiens	0-6
2550081-2	1989	All three drugs stimulated 2--4-fold OH radical formation in cardiac microsomes which was inhibited by SOD and catalase.	oh radical	37-47	catalase	Rattus norvegicus	111-119
2722888-1	1989	The interaction between superoxide dismutase (SOD) and peroxide, under anaerobic conditions in the presence of an OH radical scavenger, formate, and an indicator, nitro blue tetrazolium, involves five reactions and an equilibrium: (table; see text) Reaction 3 occurs at a rate that is proportional to both peroxide and enzyme with no kinetic evidence for any intermediate peroxide-enzyme complex.	oh radical	114-124	superoxide dismutase 1	Homo sapiens	46-49
32186188-2	2020	Co(II) or Co(III) can activate PAA to produce acetyloxyl (CH3C(O)O ) and acetylperoxyl (CH3C(O)OO ) radicals with little  OH radical formation, and Co(II)/Co(III) is cycled.	oh radical	122-132	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	0-6
814406-3	1976	The enzymatic destruction of oxidizing products produced during metabolic reduction of oxygen in the cell (such as singlet oxygen, H2O2 and OH radical) involves the concerted action of superoxide dismutase-which removes O-2 and yields H2O2-and H2O2 removing enzymes such as catalase and glutathione peroxidase.	oh radical	140-150	catalase	Homo sapiens	274-282
4546241-1	1974	V. Phosphate elimination from ribose-5-phosphate after OH radical attack at C-4.	oh radical	55-65	complement C4A (Rodgers blood group)	Homo sapiens	76-79
33646781-2	2021	In the present research, the spin dynamics of the organic radicals generated by the  OH radical was investigated by means of a time-resolved electron spin resonance (TR-ESR) method with the pulsed laser irradiation on H2O2 in aqueous solution.	oh radical	85-95	coagulation factor II thrombin receptor	Homo sapiens	166-168
32593823-5	2020	Integrating the trapping experiments and electrochemical analysis, we found the oxygen vacancy on B-TiO2-x capturing the electrons to promote the separation of photogenerated charges, meanwhile the Co(II) in the composite decomposed hydrogen peroxide (H2O2) to produce more  OH radical.	oh radical	275-285	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	198-204
3713815-4	1986	However, nitro-PAH may also be formed during source-receptor transport by atmospheric reactions of adsorbed or gas-phase PAH with oxides of nitrogen, nitric acid and other atmospherically important species such as the OH radical.	oh radical	218-228	Henna	Drosophila melanogaster	15-18
3713815-4	1986	However, nitro-PAH may also be formed during source-receptor transport by atmospheric reactions of adsorbed or gas-phase PAH with oxides of nitrogen, nitric acid and other atmospherically important species such as the OH radical.	oh radical	218-228	Henna	Drosophila melanogaster	121-124
4052410-9	1985	Its mechanism of formation is believed to involve OH radical addition to the C-8 position of guanine followed by oxidation of the radical adduct.	oh radical	50-60	homeobox C8	Homo sapiens	77-80
34056355-8	2021	As a mechanism, linoleate hydroperoxide formation and its decomposition in the presence of myoglobin (or heme) to generate the OH radical seem to be involved in the ethanol-to-AcAld conversion.	oh radical	127-137	myoglobin	Homo sapiens	91-100
33338722-5	2021	The overall reaction rate coefficient for camphene + OH radical is 2.1 10-12 cm3 molecule-1 sec-1 at 298 K and 1 atm which agree well with the experimental reaction rate coefficient (5.58 10-11 cm3 molecule-1 sec-1) for the reaction of camphene with OH radical.	oh radical	53-63	secretory blood group 1, pseudogene	Homo sapiens	92-97
33338722-5	2021	The overall reaction rate coefficient for camphene + OH radical is 2.1 10-12 cm3 molecule-1 sec-1 at 298 K and 1 atm which agree well with the experimental reaction rate coefficient (5.58 10-11 cm3 molecule-1 sec-1) for the reaction of camphene with OH radical.	oh radical	53-63	secretory blood group 1, pseudogene	Homo sapiens	209-214
33338722-5	2021	The overall reaction rate coefficient for camphene + OH radical is 2.1 10-12 cm3 molecule-1 sec-1 at 298 K and 1 atm which agree well with the experimental reaction rate coefficient (5.58 10-11 cm3 molecule-1 sec-1) for the reaction of camphene with OH radical.	oh radical	250-260	secretory blood group 1, pseudogene	Homo sapiens	92-97
33338722-5	2021	The overall reaction rate coefficient for camphene + OH radical is 2.1 10-12 cm3 molecule-1 sec-1 at 298 K and 1 atm which agree well with the experimental reaction rate coefficient (5.58 10-11 cm3 molecule-1 sec-1) for the reaction of camphene with OH radical.	oh radical	250-260	secretory blood group 1, pseudogene	Homo sapiens	209-214
33338722-6	2021	The branching ratio for the addition of OH radical to the C10 position of camphene is 68.32%, and the C7 position of camphene is 31.68% at 298 K. The calculated lifetime reveals that camphene degrades quickly in the atmosphere owing to its short lifetime of 5.3 h. The obtained mechanistic and kinetic results reveal that the addition of OH radical to the C10 position is more dominant than the C7 position, and it is more stable and spontaneous in the atmosphere.	oh radical	40-50	homeobox C10	Homo sapiens	58-61
33338722-6	2021	The branching ratio for the addition of OH radical to the C10 position of camphene is 68.32%, and the C7 position of camphene is 31.68% at 298 K. The calculated lifetime reveals that camphene degrades quickly in the atmosphere owing to its short lifetime of 5.3 h. The obtained mechanistic and kinetic results reveal that the addition of OH radical to the C10 position is more dominant than the C7 position, and it is more stable and spontaneous in the atmosphere.	oh radical	40-50	homeobox C10	Homo sapiens	356-359
33338722-6	2021	The branching ratio for the addition of OH radical to the C10 position of camphene is 68.32%, and the C7 position of camphene is 31.68% at 298 K. The calculated lifetime reveals that camphene degrades quickly in the atmosphere owing to its short lifetime of 5.3 h. The obtained mechanistic and kinetic results reveal that the addition of OH radical to the C10 position is more dominant than the C7 position, and it is more stable and spontaneous in the atmosphere.	oh radical	338-348	homeobox C10	Homo sapiens	58-61
33052996-0	2020	On the propagation of the OH radical produced by Cu-amyloid beta peptide model complexes.	oh radical	26-36	amyloid beta precursor protein	Homo sapiens	52-64
33052996-5	2020	In the present paper, we investigate on the basis of molecular modelling computations the mechanism of OH radical propagation toward the Abeta peptide, starting from the end-product of OH radical generation by Cu(ii) Abeta.	oh radical	103-113	amyloid beta precursor protein	Homo sapiens	137-142
33052996-5	2020	In the present paper, we investigate on the basis of molecular modelling computations the mechanism of OH radical propagation toward the Abeta peptide, starting from the end-product of OH radical generation by Cu(ii) Abeta.	oh radical	103-113	amyloid beta precursor protein	Homo sapiens	217-222
33052996-5	2020	In the present paper, we investigate on the basis of molecular modelling computations the mechanism of OH radical propagation toward the Abeta peptide, starting from the end-product of OH radical generation by Cu(ii) Abeta.	oh radical	185-195	amyloid beta precursor protein	Homo sapiens	137-142
33052996-5	2020	In the present paper, we investigate on the basis of molecular modelling computations the mechanism of OH radical propagation toward the Abeta peptide, starting from the end-product of OH radical generation by Cu(ii) Abeta.	oh radical	185-195	amyloid beta precursor protein	Homo sapiens	217-222
32186188-2	2020	Co(II) or Co(III) can activate PAA to produce acetyloxyl (CH3C(O)O ) and acetylperoxyl (CH3C(O)OO ) radicals with little  OH radical formation, and Co(II)/Co(III) is cycled.	oh radical	122-132	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	10-17
32186188-2	2020	Co(II) or Co(III) can activate PAA to produce acetyloxyl (CH3C(O)O ) and acetylperoxyl (CH3C(O)OO ) radicals with little  OH radical formation, and Co(II)/Co(III) is cycled.	oh radical	122-132	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	10-16
29763558-1	2018	In the present work, the reaction mechanism of two segregated hydrofluoroethers (HFEs), CH3OCF3 (HFE-143a) and CH3OCHF2 (HFE-152a), and a nonsegregated HFE, CHF2OCH2CF3 (HFE-245fa2), with OH radical is studied using electronic structure calculations.	oh radical	188-198	homeostatic iron regulator	Homo sapiens	81-84
31052893-1	2019	A ground-based system for measuring tropospheric OH radical based on laser-induced fluorescence (AIOFM-LIF) was developed in this work.	oh radical	49-59	LIF interleukin 6 family cytokine	Homo sapiens	103-106
31052893-12	2019	The deployment of AIOFM-LIF system in STORM campaign has demonstrated its capability of measuring tropospheric OH radical with high sensitivity and accuracy in a polluted environment.	oh radical	111-121	LIF interleukin 6 family cytokine	Homo sapiens	24-27
30192520-6	2018	Observed C10-RO2 radicals from alpha-pinene ozonolysis were O,O-C10H15(O2) xO2 with x = 0, 1, 2, 3 and from the OH radical reaction HO-C10H16(O2)alphaO2 with alpha = 0, 1, 2.	oh radical	112-122	chromosome 12 open reading frame 57	Homo sapiens	9-12
30137992-1	2018	The reaction of the OH radical with isoprene, C5H8 (R1), has been studied over the temperature range 298-794 K and bath gas pressures of nitrogen from 50 to 1670 Torr using laser flash photolysis (LFP) to generate OH and laser-induced fluorescence (LIF) to observe OH removal.	oh radical	20-30	CD1b molecule	Homo sapiens	46-54
29442654-5	2018	It demonstrated the mechanism of photodegration was that  OH radical generated by graphene-CdS composite plays a vital role by adding dimethyl sulfoxide (DMSO).	oh radical	58-68	CDP-diacylglycerol synthase 1	Homo sapiens	91-94
31627442-7	2019	On X-ray irradiation, the cells enhanced their  OH radical generation, which subsequently induced gammaH2AX, a marker of DNA double-strand breaks in their nuclei, but decreased mitochondrial membrane potential.	oh radical	48-58	H2A.X variant histone	Mus musculus	98-107
30801172-6	2019	The electrochemical analysis for the electron transfers on Cu xP and CoP showed that the number of electrons transferred to O2 is 3 and 2, respectively, which explains why OH radical is generated on Cu xP, not on CoP.	oh radical	172-182	caspase recruitment domain family member 16	Homo sapiens	69-72
30596495-1	2019	A reaction class transition state theory (RC-TST) augmented with structure-activity relationship (SAR) methodology is applied to predict high-pressure limit thermal rate constants for hydrogen abstraction by  OH radical from polycyclic aromatic hydrocarbons (PAHs) reaction class in the temperature range of 300-3000 K. The rate constants for the reference reaction of C6H6 +  OH   C6H5 + H2O is calculated by the canonical variational transition state theory (CVT) with small curvature tunneling (SCT).	oh radical	209-219	thiosulfate sulfurtransferase	Homo sapiens	45-48
29763558-1	2018	In the present work, the reaction mechanism of two segregated hydrofluoroethers (HFEs), CH3OCF3 (HFE-143a) and CH3OCHF2 (HFE-152a), and a nonsegregated HFE, CHF2OCH2CF3 (HFE-245fa2), with OH radical is studied using electronic structure calculations.	oh radical	188-198	homeostatic iron regulator	Homo sapiens	97-100
29763558-1	2018	In the present work, the reaction mechanism of two segregated hydrofluoroethers (HFEs), CH3OCF3 (HFE-143a) and CH3OCHF2 (HFE-152a), and a nonsegregated HFE, CHF2OCH2CF3 (HFE-245fa2), with OH radical is studied using electronic structure calculations.	oh radical	188-198	homeostatic iron regulator	Homo sapiens	97-100
29763558-1	2018	In the present work, the reaction mechanism of two segregated hydrofluoroethers (HFEs), CH3OCF3 (HFE-143a) and CH3OCHF2 (HFE-152a), and a nonsegregated HFE, CHF2OCH2CF3 (HFE-245fa2), with OH radical is studied using electronic structure calculations.	oh radical	188-198	homeostatic iron regulator	Homo sapiens	97-100
29763558-2	2018	The initial reaction between HFE and OH radical is studied by considering two (three for CHF2OCH2CF3) pathways, H-atom abstraction and C-O bond breaking, OH addition reaction and C-C bond breaking, and OH addition reaction, which leads to the formation of alkyl radical intermediate.	oh radical	37-47	homeostatic iron regulator	Homo sapiens	29-32
30474033-1	2016	The inhibition effect of tert-butyl alcohol (TBA), identified as the  OH radical inhibitor, on the TiO2 nano assays (TNA) photoelectrocatalytic oxidation of different organics such as glucose and phthalate was reported.	oh radical	70-80	telomerase reverse transcriptase	Homo sapiens	25-29
29513990-6	2018	Consistent with experiment, our calculations indicate that the reactivity toward OH radical addition is reduced as ( Z)-CHF2CF CHCl > ( E)-CHF2CF CHCl > ( E)-CF3CF CHCl > ( Z)-CF3CF CHCl, where the ( E)/( Z) reactivity is reversed for CF3CF CHCl and CHF2CF CHCl.	oh radical	81-91	hes related family bHLH transcription factor with YRPW motif 1	Homo sapiens	120-124
26139411-5	2015	It demonstrated that Adda chain was cleaved from the MC-LR cyclic peptide by OH radical attack after plasma discharge in the presence of catalysts, and the generated nontoxic products can be further easily degraded in the biological treatment.	oh radical	77-87	adducin 1	Homo sapiens	21-25