PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 2587125-2 1989 SOD activity in PMN was measured with nitroblue tetrazolium reduction assay on PAGE, and the SOD content in PMN was determined with an ELISA using a monoclonal antibody against human copper and zinc-containing SOD. Nitroblue Tetrazolium 38-59 superoxide dismutase 1 Homo sapiens 0-3 2625004-0 1989 Binding of nitroblue tetrazolium to human serum albumin in a fructosamine test. Nitroblue Tetrazolium 11-32 albumin Homo sapiens 42-55 2529540-4 1989 Loss of MYC seems to be associated with granulocytic differentiation because the time course of its loss was similar to that of appearance of nitroblue tetrazolium-positive cells, mature granulocytes, and its loss was not observed on differentiation of HL-60 cells into macrophages induced by phorbol 12-myristate 13-acetate or teleocidin. Nitroblue Tetrazolium 142-163 MYC proto-oncogene, bHLH transcription factor Homo sapiens 8-11 2474569-4 1989 Incubation of human monocytes with anti-CD36 MAbs or IRBC resulted in stimulation of the respiratory burst as measured by reduction of nitroblue tetrazolium and generation of chemiluminescence. Nitroblue Tetrazolium 135-156 CD36 molecule Homo sapiens 40-44 2722888-1 1989 The interaction between superoxide dismutase (SOD) and peroxide, under anaerobic conditions in the presence of an OH radical scavenger, formate, and an indicator, nitro blue tetrazolium, involves five reactions and an equilibrium: (table; see text) Reaction 3 occurs at a rate that is proportional to both peroxide and enzyme with no kinetic evidence for any intermediate peroxide-enzyme complex. Nitroblue Tetrazolium 163-185 superoxide dismutase 1 Homo sapiens 24-44 2722888-1 1989 The interaction between superoxide dismutase (SOD) and peroxide, under anaerobic conditions in the presence of an OH radical scavenger, formate, and an indicator, nitro blue tetrazolium, involves five reactions and an equilibrium: (table; see text) Reaction 3 occurs at a rate that is proportional to both peroxide and enzyme with no kinetic evidence for any intermediate peroxide-enzyme complex. Nitroblue Tetrazolium 163-185 superoxide dismutase 1 Homo sapiens 46-49 2472158-8 1989 When the lower adherence was corrected for, IFN-alpha enhanced NBT reduction. Nitroblue Tetrazolium 63-66 interferon alpha 1 Homo sapiens 44-53 2497971-3 1989 Assessing suspension cultures containing cells from patients with acute myeloid leukemia (11 patients) or myeloid blast crisis of chronic myeloid leukemia (5 patients), it was found that recombinant human TNF-alpha and IFN-gamma significantly enhanced the number of cells reducing nitroblue tetrazolium, as compared to control cultures containing no cytokine (P less than 0.001 and P less than 0.001, respectively). Nitroblue Tetrazolium 281-302 tumor necrosis factor Homo sapiens 205-214 2497971-3 1989 Assessing suspension cultures containing cells from patients with acute myeloid leukemia (11 patients) or myeloid blast crisis of chronic myeloid leukemia (5 patients), it was found that recombinant human TNF-alpha and IFN-gamma significantly enhanced the number of cells reducing nitroblue tetrazolium, as compared to control cultures containing no cytokine (P less than 0.001 and P less than 0.001, respectively). Nitroblue Tetrazolium 281-302 interferon gamma Homo sapiens 219-228 2547045-1 1989 When a liver perfusion with nitro blue tetrazolium (NBT) and phorbol myristate acetate (PMA) was performed in carbon tetrachloride (CCl4)-intoxicated rats, formazan deposition was remarkable in macrophages in the necrotic areas of the liver, its intensity varying with the extent of injury. Nitroblue Tetrazolium 28-50 C-C motif chemokine ligand 4 Rattus norvegicus 132-136 2722807-6 1989 Human DIF-A was found to induce maturation of human and murine leukemic cells into both macrophage-like cells with nitro blue tetrazolium reducing activity and phagocytic cells, but was found to suppress proliferation of these leukemic cells. Nitroblue Tetrazolium 115-137 LIF interleukin 6 family cytokine Homo sapiens 6-9 2547324-5 1989 The inclusion of BCS in the NBT assay system was shown to make the accurate measurement of SOD activity in tissues with interferences possible. Nitroblue Tetrazolium 28-31 superoxide dismutase 1 Homo sapiens 91-94 2547045-3 1989 The formazan content after incubation with NBT and PMA was higher in macrophages isolated from CCl4-intoxicated liver than in those from normal liver, though their PMA-induced chemiluminescence did not differ. Nitroblue Tetrazolium 43-46 C-C motif chemokine ligand 4 Rattus norvegicus 95-99 2558980-2 1989 NAD[P]H + phenazine + O2 was found to reduce nitroblue tetrazolium, iodonitrotetrazolium, and thiazolyl blue in a manner sensitive to agents that dismutase O2-., viz., SOD and Mn(II). Nitroblue Tetrazolium 45-66 superoxide dismutase 1 Homo sapiens 168-171 3136768-1 1988 Porcine kidney diamine oxidase, a PQQ-enzyme, can be directly measured by formazan production with putrescine and nitroblue tetrazolium. Nitroblue Tetrazolium 114-135 amine oxidase copper containing 1 Homo sapiens 15-30 2586142-5 1989 If the leukemia cells were pretreated with a kind of PKC inhibitor such as trifluoperazine, the increase of PKC activity was inhibited, and the rate of nitroblue tetrazolium reduction decreased from 89.9 +/- 7.7% to 62 +/- 25% (n = 6, p less than 0.01) and the mature cells reduced from 63.1 +/- 11.7% to 19.7 +/- 12.2% (p less than 0.01). Nitroblue Tetrazolium 152-173 proline rich transmembrane protein 2 Homo sapiens 53-56 3278750-6 1988 Subpopulation recruitment by GM-CSF treatment was also demonstrated by the FMLP-elicited NBT test. Nitroblue Tetrazolium 89-92 colony stimulating factor 2 Homo sapiens 29-35 2843172-9 1988 Myeloperoxidase catalytically inhibited O2- -dependent reduction of Nitro Blue Tetrazolium. Nitroblue Tetrazolium 68-90 myeloperoxidase Homo sapiens 0-15 2459585-3 1988 The enhancement of NBT reduction by tyrosine phosphate was blocked by superoxide dismutase (SOD). Nitroblue Tetrazolium 19-22 superoxide dismutase 1 Homo sapiens 70-90 2459585-3 1988 The enhancement of NBT reduction by tyrosine phosphate was blocked by superoxide dismutase (SOD). Nitroblue Tetrazolium 19-22 superoxide dismutase 1 Homo sapiens 92-95 3209423-6 1988 This compared to a non-linear reduction of NBT during the initial stages of the reactions (SDH and "nothing dehydrogenase") when using PMS and cyanide. Nitroblue Tetrazolium 43-46 succinate dehydrogenase complex iron sulfur subunit B Homo sapiens 91-94 3278750-6 1988 Subpopulation recruitment by GM-CSF treatment was also demonstrated by the FMLP-elicited NBT test. Nitroblue Tetrazolium 89-92 formyl peptide receptor 1 Homo sapiens 75-79 3132023-2 1988 We reported a modified procedure for histochemical demonstration of guanase in human tissues involving hydrolytic deamination of the substrate guanine to xanthine via guanase, and then oxidation of xanthine to uric acid, with concomitant reduction of nitrotetrazolium blue (NBT). Nitroblue Tetrazolium 251-272 guanine deaminase Homo sapiens 68-75 3349599-1 1988 This assay for superoxide dismutase (SOD, EC 1.15.1.1) activity involves inhibition of nitroblue tetrazolium reduction, with xanthine-xanthine oxidase used as a superoxide generator. Nitroblue Tetrazolium 87-108 superoxide dismutase 1 Homo sapiens 15-35 3349599-1 1988 This assay for superoxide dismutase (SOD, EC 1.15.1.1) activity involves inhibition of nitroblue tetrazolium reduction, with xanthine-xanthine oxidase used as a superoxide generator. Nitroblue Tetrazolium 87-108 superoxide dismutase 1 Homo sapiens 37-40 3132023-2 1988 We reported a modified procedure for histochemical demonstration of guanase in human tissues involving hydrolytic deamination of the substrate guanine to xanthine via guanase, and then oxidation of xanthine to uric acid, with concomitant reduction of nitrotetrazolium blue (NBT). Nitroblue Tetrazolium 274-277 guanine deaminase Homo sapiens 68-75 2820533-5 1987 In a dose-dependent fashion, TNF enhanced HL-60 cell nonspecific esterase activity, H2O2 production, NBT reduction, and acid phosphatase content. Nitroblue Tetrazolium 101-104 tumor necrosis factor Homo sapiens 29-32 2838494-4 1988 A test for fructosamine quantification is based on nitroblue tetrazolium (NBT) reduction, in which O2- is involved, the reduction being inhibited in the presence of superoxide dismutase (SOD). Nitroblue Tetrazolium 51-72 superoxide dismutase 1 Homo sapiens 165-185 2838494-4 1988 A test for fructosamine quantification is based on nitroblue tetrazolium (NBT) reduction, in which O2- is involved, the reduction being inhibited in the presence of superoxide dismutase (SOD). Nitroblue Tetrazolium 51-72 superoxide dismutase 1 Homo sapiens 187-190 2838494-4 1988 A test for fructosamine quantification is based on nitroblue tetrazolium (NBT) reduction, in which O2- is involved, the reduction being inhibited in the presence of superoxide dismutase (SOD). Nitroblue Tetrazolium 74-77 superoxide dismutase 1 Homo sapiens 165-185 2838494-4 1988 A test for fructosamine quantification is based on nitroblue tetrazolium (NBT) reduction, in which O2- is involved, the reduction being inhibited in the presence of superoxide dismutase (SOD). Nitroblue Tetrazolium 74-77 superoxide dismutase 1 Homo sapiens 187-190 2838494-9 1988 Reduction of NBT by the Amadori compounds formed is inhibited by SOD. Nitroblue Tetrazolium 13-16 superoxide dismutase 1 Homo sapiens 65-68 2848181-4 1988 Peritoneal exudate macrophages (PEM) of guinea pigs exposed in vitro to various doses of CRP for 72 hr resulted in the development of O2- production dose-dependently, measured by increases in superoxide dismutase-inhibitable nitro blue tetrazolium reduction. Nitroblue Tetrazolium 225-247 C-reactive protein Cavia porcellus 89-92 3123808-5 1988 In the responsive patients morphologic changes consistent with monocytic maturation, as well as a strong increase of alpha-naphthyl acetate esterase activity and of nitroblue tetrazolium reducing capability were observed upon culture with rIFN-gamma. Nitroblue Tetrazolium 165-186 interferon gamma Rattus norvegicus 239-249 3498485-2 1987 Concomitantly, IL-1 stimulated the prostaglandin E2 synthesis and nitroblue tetrazolium dye-reducing capacity of JOSK-I cells. Nitroblue Tetrazolium 66-87 interleukin 1 alpha Homo sapiens 15-19 3607277-2 1987 Normal human eosinophils were found to respond to formyl-methionyl-leucyl-phenylalanine (fMLP) at concentrations greater than 10(-7) mol/L with an increase in the concentration of intracellular free calcium, oxygen consumption, nitroblue tetrazolium reduction, and chemiluminescence. Nitroblue Tetrazolium 228-249 formyl peptide receptor 1 Homo sapiens 89-93 3663400-1 1987 It has been established that the pyrogallol autoxidation method for the estimation of the activity of superoxide dismutase (SOD) (EC 1.15.1.1) is superior in precision and sensitivity to a superoxide-generating method (NADH/phenazine methosulfate linked to nitroblue tetrazolium reduction). Nitroblue Tetrazolium 257-278 superoxide dismutase 1 Homo sapiens 102-122 3663400-1 1987 It has been established that the pyrogallol autoxidation method for the estimation of the activity of superoxide dismutase (SOD) (EC 1.15.1.1) is superior in precision and sensitivity to a superoxide-generating method (NADH/phenazine methosulfate linked to nitroblue tetrazolium reduction). Nitroblue Tetrazolium 257-278 superoxide dismutase 1 Homo sapiens 124-127 3801673-2 1987 Buffy coat granulocytes incubated with as little as 0.5 ng/mL of recombinant TNF (rTNF) showed a dose-related increase in nitroblue tetrazolium dye reduction, in granulocyte polarization, in superoxide anion release, and in visually apparent aggregation. Nitroblue Tetrazolium 122-143 tumor necrosis factor Homo sapiens 77-80 3109415-1 1987 Natural or recombinant human tumor necrosis factor (TNF) induced NBT-reducing activity of ML-1 cells in a dose-dependent manner. Nitroblue Tetrazolium 65-68 tumor necrosis factor Homo sapiens 29-50 3109415-1 1987 Natural or recombinant human tumor necrosis factor (TNF) induced NBT-reducing activity of ML-1 cells in a dose-dependent manner. Nitroblue Tetrazolium 65-68 tumor necrosis factor Homo sapiens 52-55 3109415-2 1987 Interferon-gamma (IFN-gamma) induced NBT-reducing activity only marginally. Nitroblue Tetrazolium 37-40 interferon gamma Homo sapiens 0-27 3109415-3 1987 However, when IFN-gamma was combined with TNF, induction of NBT-reducing activity was remarkably increased. Nitroblue Tetrazolium 60-63 interferon gamma Homo sapiens 14-23 3109415-3 1987 However, when IFN-gamma was combined with TNF, induction of NBT-reducing activity was remarkably increased. Nitroblue Tetrazolium 60-63 tumor necrosis factor Homo sapiens 42-45 3109415-5 1987 Treatment with both TNF and IFN-gamma synergistically enhanced morphological changes, growth inhibition and activity of Fc receptors, and NBT reduction in ML-1 cells, but not phagocytic activity. Nitroblue Tetrazolium 138-141 tumor necrosis factor Homo sapiens 20-23 3109415-5 1987 Treatment with both TNF and IFN-gamma synergistically enhanced morphological changes, growth inhibition and activity of Fc receptors, and NBT reduction in ML-1 cells, but not phagocytic activity. Nitroblue Tetrazolium 138-141 interferon gamma Homo sapiens 28-37 3099861-7 1987 Based on units of antiviral activity, rIFN-gamma is tenfold more active than rIFN-alpha D in inducing EA rosettes and 40-fold more active in inducing nitroblue tetrazolium reduction and immunophagocytosis. Nitroblue Tetrazolium 150-171 interferon gamma Rattus norvegicus 38-48 3606573-4 1987 The induction of P47 by retinoic acid preceded cessation of cell proliferation and development of the capacity to reduce Nitro Blue Tetrazolium, indicating that its expression is an early event in the myeloid differentiation of HL-60 cells. Nitroblue Tetrazolium 121-143 pleckstrin Homo sapiens 17-20 2441083-4 1987 These results suggest that cytochrome c is directly reduced by the cuprous ion released from bleomycin-Cu (II) in a reducing reaction with cysteine and nitroblue tetrazolium chloride is reduced by the superoxide anion formed in the reaction of the cuprous ion with oxygen. Nitroblue Tetrazolium 152-182 cytochrome c, somatic Homo sapiens 27-39 3102606-4 1987 Appearance of the monocytic phenotype was manifested within 24 hr of IFN-gamma exposure by: increased nitroblue tetrazolium reduction; increased cell surface expression of the HLA-DR, Mo1, and MY4 antigens; and induction of transcripts for the second component of complement (C2) and tumor necrosis factor. Nitroblue Tetrazolium 102-123 interferon gamma Homo sapiens 69-78 3098042-0 1986 Effect of fibroblast interferon and recombinant gamma interferon on zymosan-induced nitroblue tetrazolium reduction in mouse peritoneal macrophages. Nitroblue Tetrazolium 84-105 interferon gamma Mus musculus 48-64 2946400-3 1986 The number of cells with the ability to reduce nitroblue tetrazolium increased in the TPA-treated cell lines HL-60, ML-3, THP-1, and U-937, whereas the cell lines KG-1 and KLM-2 remained nitroblue tetrazolium negative. Nitroblue Tetrazolium 47-68 GLI family zinc finger 2 Homo sapiens 122-127 3027925-2 1986 The appearance of superoxide anion radical in cerebral extracellular space during VIP application was examined by measuring the rate of superoxide dismutase (SOD)-inhibitable reduction of nitroblue tetrazolium (NBT). Nitroblue Tetrazolium 188-209 vasoactive intestinal peptide Felis catus 82-85 3027925-2 1986 The appearance of superoxide anion radical in cerebral extracellular space during VIP application was examined by measuring the rate of superoxide dismutase (SOD)-inhibitable reduction of nitroblue tetrazolium (NBT). Nitroblue Tetrazolium 211-214 vasoactive intestinal peptide Felis catus 82-85 3027925-3 1986 Although VIP (1 and 10 micrograms/ml) caused substantial reduction of NBT, the rate of the SOD-inhibitable portion was not significantly different from zero. Nitroblue Tetrazolium 70-73 vasoactive intestinal peptide Felis catus 9-12 2836672-6 1987 Zymosan-induced NBT reduction increased slightly during monocyte to macrophage differentiation and was further enhanced by continuous presence of IFN gamma. Nitroblue Tetrazolium 16-19 interferon gamma Homo sapiens 146-155 3025874-5 1987 and reduce nitroblue tetrazolium dye on appropriate stimulation; they respond chemotactically to erythrocytes destroyed by laser microirradiation or to the specific chemoattractants fMet-Leu-Phe (10 nM) and C5a (zymosan-activated serum); and they ingest and kill staphylococci. Nitroblue Tetrazolium 11-32 complement C5a receptor 1 Homo sapiens 207-210 3096330-2 1986 Both IFN-gamma and rTNF-alpha induced the appearance of the monocytic phenotype in a dose- and time-dependent manner as assessed by morphology, reduction of nitroblue tetrazolium and the induction of alpha-naphthyl butyrate esterase. Nitroblue Tetrazolium 157-178 interferon gamma Homo sapiens 5-14 3096330-2 1986 Both IFN-gamma and rTNF-alpha induced the appearance of the monocytic phenotype in a dose- and time-dependent manner as assessed by morphology, reduction of nitroblue tetrazolium and the induction of alpha-naphthyl butyrate esterase. Nitroblue Tetrazolium 157-178 tumor necrosis factor Rattus norvegicus 19-29 3093627-2 1986 After 5 d of culture in the presence of rTNF and LT, a significant proportion of the myeloid cell lines express monocyte differentiation antigens and ANAE activity, and become able to reduce nitroblue tetrazolium (NBT) and mediate low levels of ADCC against tumor target cells. Nitroblue Tetrazolium 191-212 tumor necrosis factor Rattus norvegicus 40-51 3093627-2 1986 After 5 d of culture in the presence of rTNF and LT, a significant proportion of the myeloid cell lines express monocyte differentiation antigens and ANAE activity, and become able to reduce nitroblue tetrazolium (NBT) and mediate low levels of ADCC against tumor target cells. Nitroblue Tetrazolium 214-217 tumor necrosis factor Rattus norvegicus 40-51 3017475-8 1986 The percentage of depolarizing PMNs in response to FMLP was significantly correlated with the percentage of NBT-positive cells from both purified PMNs and from whole blood (r = .849, P less than .0005, r = .857, P less than .05, respectively), and with the amount of superoxide produced, expressed as a percentage of that amount produced by cytochalasin B (cyto-B)-pretreated cells (r = .565, P less than .01). Nitroblue Tetrazolium 108-111 formyl peptide receptor 1 Homo sapiens 51-55 2411582-1 1985 The monoblastlike leukemia cell line, U-937, is induced to differentiate into monocytelike cells by incubation with 200-500 U/ml of recombinant human immune interferon (IFN-gamma) judging from capacity to reduce nitroblue tetrazolium. Nitroblue Tetrazolium 212-233 interferon gamma Homo sapiens 150-178 3955232-8 1986 Stimulated nitroblue tetrazolium (NBT) tests performed on PMNs from mothers of CGD patients indicated that cytochrome b deficiency was associated with X-linked inheritance, except in one case in which probable autosomal recessive inheritance was demonstrated. Nitroblue Tetrazolium 11-32 mitochondrially encoded cytochrome b Homo sapiens 107-119 2417997-5 1985 Next the D-glyceraldehyde-3-phosphate is oxidized by exogenous and endogenous glyceraldehyde-3-phosphate dehydrogenase and the electrons are transported concomitantly via NAD+, phenazine methosulphate and menadione to nitro-BT. Nitroblue Tetrazolium 218-226 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 78-118 4052375-5 1985 ETF-QO catalyzes the transfer of electrons from electron-transfer flavoprotein (ETF) to nitro blue tetrazolium, with a sluggish reaction turnover number of about 10-30 min-1. Nitroblue Tetrazolium 88-110 ETF dehydrogenase Sus scrofa 0-6 4030398-2 1985 The tetrazolium salt tetranitro blue tetrazolium is recommended for the localization of MAO activity, rather than nitro blue tetrazolium or BPST [2-(2-benzothiazolyl)-3-(4-phthalhydrazidyl)-5-styryl-tetrazolium] . Nitroblue Tetrazolium 26-48 monoamine oxidase A Rattus norvegicus 88-91 2990646-4 1985 The cell lysis by the superoxide-generating xanthine oxidase system was not significantly increased by SOD, but was significantly decreased by nitroblue tetrazolium and completely abolished by catalase. Nitroblue Tetrazolium 143-164 xanthine dehydrogenase Mus musculus 44-60 3886800-12 1985 The results of experiments with scavengers of oxygen reduction intermediates and of nitroblue tetrazolium reduction tests indicated that H2O2, O2- and 1O2 were involved in the killing of AMA by LF-treated MPM. Nitroblue Tetrazolium 84-105 heme oxygenase 2 Homo sapiens 137-154 2991135-0 1985 NBT dye reduction test & myeloperoxidase activity of neutrophils in pregnant & non-pregnant women. Nitroblue Tetrazolium 0-3 myeloperoxidase Homo sapiens 29-44 3922297-5 1985 Bovine liver catalase enhanced the rate of nitroblue tetrazolium reduction and decreased the maximal velocity of the reaction proportionately to catalase concentration. Nitroblue Tetrazolium 43-64 catalase Bos taurus 13-21 6607753-5 1984 DIF induced maturation of HL-60 into phagocytizing nitro blue tetrazolium reducing cells with the morphological characteristics of myelomonocytic or monocyte-like cells. Nitroblue Tetrazolium 51-73 tumor necrosis factor Homo sapiens 0-3 2981163-1 1985 In this new method for determining serum guanase activity by use of the Hitachi 736-40 automated analyzer, serum is incubated with a mixture of xanthine oxidase, superoxide dismutase, and catalase; a reagent containing KCN, guanine, nitrotetrazolium blue, and Triton X-100 is added; and the increase in absorbance at 570 and 660 nm is measured for 2.4 min. Nitroblue Tetrazolium 233-254 guanine deaminase Homo sapiens 41-48 6327830-5 1984 NBT reduction by visible light could be slightly inhibited by SOD, but a 12% decrease of NBT reduction by UV radiation could be shown with the addition of SOD. Nitroblue Tetrazolium 0-3 superoxide dismutase 1 Homo sapiens 62-65 6327830-5 1984 NBT reduction by visible light could be slightly inhibited by SOD, but a 12% decrease of NBT reduction by UV radiation could be shown with the addition of SOD. Nitroblue Tetrazolium 89-92 superoxide dismutase 1 Homo sapiens 155-158 6723060-0 1984 Isolation of human fibrinogen using nitroblue tetrazolium (NBT). Nitroblue Tetrazolium 36-57 fibrinogen beta chain Homo sapiens 19-29 6723060-0 1984 Isolation of human fibrinogen using nitroblue tetrazolium (NBT). Nitroblue Tetrazolium 59-62 fibrinogen beta chain Homo sapiens 19-29 6495349-5 1984 Microspectrophotometric measurements of matched controls and NBT/acetone preincubated sections show that the preincubation step may slightly decrease lactate dehydrogenase (LDH) and glucose-6-phosphate dehydrogenase (G6PDH) activities. Nitroblue Tetrazolium 61-64 glucose-6-phosphate dehydrogenase Homo sapiens 182-215 6495349-5 1984 Microspectrophotometric measurements of matched controls and NBT/acetone preincubated sections show that the preincubation step may slightly decrease lactate dehydrogenase (LDH) and glucose-6-phosphate dehydrogenase (G6PDH) activities. Nitroblue Tetrazolium 61-64 glucose-6-phosphate dehydrogenase Homo sapiens 217-222 6607753-6 1984 An activity, co-chromatographing with DIF, acts synergistically with retinoic acid to induce maturation not only of HL-60, but also of the monoblast-like cell line U-937 (measured as percentage of cells reducing NBT). Nitroblue Tetrazolium 212-215 tumor necrosis factor Homo sapiens 38-41 6362847-5 1983 Nitroblue tetrazolium (NBT) reduction by resting granulocytes was slightly, although not significantly, increased by preincubation with IFN for 30 min, but their NBT reduction during phagocytosis of E. coli was significantly increased. Nitroblue Tetrazolium 0-21 interferon alpha 1 Homo sapiens 136-139 6196020-2 1983 Monoamine-oxidase (MAO) activity was detected in rat pineal gland with dopamine, 5-hydroxytryptamine (5-HT), norepinephrine and tryptamine as substrates, and nitroblue tetrazolium salt as electron acceptor. Nitroblue Tetrazolium 158-184 monoamine oxidase A Rattus norvegicus 0-17 6196020-2 1983 Monoamine-oxidase (MAO) activity was detected in rat pineal gland with dopamine, 5-hydroxytryptamine (5-HT), norepinephrine and tryptamine as substrates, and nitroblue tetrazolium salt as electron acceptor. Nitroblue Tetrazolium 158-184 monoamine oxidase A Rattus norvegicus 19-22 6365781-4 1984 During prolonged treatment with interferon alpha, 1 week to 1 year, granulocytes activated with bacteria exhibited a reduced Nitro Blue Tetrazolium activity in most patients. Nitroblue Tetrazolium 125-147 interferon alpha 1 Homo sapiens 32-51 6229496-8 1984 The phagocytic activity of granulocytes was not altered during IFN therapy, whereas the capacity of these cells to reduce nitroblue tetrazolium (NBT) increased after the first injection of IFN. Nitroblue Tetrazolium 122-143 interferon alpha 1 Homo sapiens 189-192 6229496-8 1984 The phagocytic activity of granulocytes was not altered during IFN therapy, whereas the capacity of these cells to reduce nitroblue tetrazolium (NBT) increased after the first injection of IFN. Nitroblue Tetrazolium 145-148 interferon alpha 1 Homo sapiens 189-192 6324308-3 1984 When cytochrome c and NBT are simultaneously present the reduction of each is about the same as when either cytochrome c or NBT is present. Nitroblue Tetrazolium 22-25 cytochrome c, somatic Homo sapiens 108-120 6324308-3 1984 When cytochrome c and NBT are simultaneously present the reduction of each is about the same as when either cytochrome c or NBT is present. Nitroblue Tetrazolium 124-127 cytochrome c, somatic Homo sapiens 5-17 6886073-2 1983 The method involves staining for newly synthesized GABA-T by the previously established nitro blue tetrazolium technique in animals killed 8-48 hours after administration of gabaculine, an irreversible inhibitor of GABA-T. Nitroblue Tetrazolium 88-110 4-aminobutyrate aminotransferase Rattus norvegicus 51-57 6301892-2 1983 delta 5-3 beta-Hydroxysteroid dehydrogenase (delta 5-3 beta-HSD) and 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) activities were detected by Dickmann and Dey"s reaction medium consisting of 1.8 mg substrate (pregnenolone or 17 beta-estradiol [E2]), 4 mg nicotinamide-adenine dinucleotide, 2 mg nitro-blue tetrazolium, 10 ml 0.1 M phosphate buffer. Nitroblue Tetrazolium 301-323 hydroxysteroid 17-beta dehydrogenase 13 Homo sapiens 69-105 6301892-2 1983 delta 5-3 beta-Hydroxysteroid dehydrogenase (delta 5-3 beta-HSD) and 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) activities were detected by Dickmann and Dey"s reaction medium consisting of 1.8 mg substrate (pregnenolone or 17 beta-estradiol [E2]), 4 mg nicotinamide-adenine dinucleotide, 2 mg nitro-blue tetrazolium, 10 ml 0.1 M phosphate buffer. Nitroblue Tetrazolium 301-323 hydroxysteroid 17-beta dehydrogenase 1 Homo sapiens 107-118 6362847-5 1983 Nitroblue tetrazolium (NBT) reduction by resting granulocytes was slightly, although not significantly, increased by preincubation with IFN for 30 min, but their NBT reduction during phagocytosis of E. coli was significantly increased. Nitroblue Tetrazolium 23-26 interferon alpha 1 Homo sapiens 136-139 6184578-5 1982 Succinate dehydrogenase and glucose-6-phosphate dehydrogenase were localized with the nitroblue tetrazolium staining reaction. Nitroblue Tetrazolium 86-107 glucose-6-phosphate dehydrogenase Homo sapiens 28-61 6291507-6 1982 gamma-Butyrobetaine hydroxylase was inhibited by a number of low-molecular-weight compounds, such as tetranitromethane, Nitro Blue Tetrazolium, adrenaline and Tiron, which may act as scavengers of superoxide anion. Nitroblue Tetrazolium 120-142 gamma-butyrobetaine hydroxylase 1 Homo sapiens 0-31 7047381-7 1982 Both ELP-Fab and ELP-Fc increase the spontaneous reduction of nitroblue-tetrazolium (NBT) in granulocytes dose-dependent in a homologous as well as in an autologous system. Nitroblue Tetrazolium 62-83 nuclear receptor subfamily 5 group A member 1 Homo sapiens 5-8 7047381-7 1982 Both ELP-Fab and ELP-Fc increase the spontaneous reduction of nitroblue-tetrazolium (NBT) in granulocytes dose-dependent in a homologous as well as in an autologous system. Nitroblue Tetrazolium 62-83 FA complementation group B Homo sapiens 9-12 7097752-0 1982 Fibronectin increases the motility, phagocytosis and NBT (nitroblue tetrazolium)-reduction of granulocytes. Nitroblue Tetrazolium 53-56 fibronectin 1 Homo sapiens 0-11 7097752-0 1982 Fibronectin increases the motility, phagocytosis and NBT (nitroblue tetrazolium)-reduction of granulocytes. Nitroblue Tetrazolium 58-79 fibronectin 1 Homo sapiens 0-11 7097752-1 1982 Neutrophilic granulocytes preincubated in vitro with human plasma fibronectin (0-1.25 mg/ml) for 30 minutes showed increased spontaneous and chemotactic migration, increased uptake of fluorescein labelled yeast particles as well as higher NBT-reduction both with and without E. coli stimulation. Nitroblue Tetrazolium 239-242 fibronectin 1 Homo sapiens 66-77 7047381-7 1982 Both ELP-Fab and ELP-Fc increase the spontaneous reduction of nitroblue-tetrazolium (NBT) in granulocytes dose-dependent in a homologous as well as in an autologous system. Nitroblue Tetrazolium 62-83 nuclear receptor subfamily 5 group A member 1 Homo sapiens 17-20 7047381-7 1982 Both ELP-Fab and ELP-Fc increase the spontaneous reduction of nitroblue-tetrazolium (NBT) in granulocytes dose-dependent in a homologous as well as in an autologous system. Nitroblue Tetrazolium 85-88 nuclear receptor subfamily 5 group A member 1 Homo sapiens 5-8 7047381-7 1982 Both ELP-Fab and ELP-Fc increase the spontaneous reduction of nitroblue-tetrazolium (NBT) in granulocytes dose-dependent in a homologous as well as in an autologous system. Nitroblue Tetrazolium 85-88 FA complementation group B Homo sapiens 9-12 7047381-7 1982 Both ELP-Fab and ELP-Fc increase the spontaneous reduction of nitroblue-tetrazolium (NBT) in granulocytes dose-dependent in a homologous as well as in an autologous system. Nitroblue Tetrazolium 85-88 nuclear receptor subfamily 5 group A member 1 Homo sapiens 17-20 6284006-4 1982 Ceruloplasmin, at concentrations present in normal plasma, inhibited reduction of both cytochrome c and nitroblue tetrazolium (NBT) mediated by the aerobic action of xanthine oxidase on hypoxanthine (a superoxide-generating system). Nitroblue Tetrazolium 104-125 ceruloplasmin Homo sapiens 0-13 6284006-4 1982 Ceruloplasmin, at concentrations present in normal plasma, inhibited reduction of both cytochrome c and nitroblue tetrazolium (NBT) mediated by the aerobic action of xanthine oxidase on hypoxanthine (a superoxide-generating system). Nitroblue Tetrazolium 127-130 ceruloplasmin Homo sapiens 0-13 6284006-6 1982 Furthermore, in an experimental system in which contact between ceruloplasmin and indicator was prevented by a relatively impermeable lipid membrane barrier, ceruloplasmin inhibited reduction of NBT trapped within liposomes exposed to xanthine oxidase and hypoxanthine. Nitroblue Tetrazolium 195-198 ceruloplasmin Homo sapiens 158-171 6284006-6 1982 Furthermore, in an experimental system in which contact between ceruloplasmin and indicator was prevented by a relatively impermeable lipid membrane barrier, ceruloplasmin inhibited reduction of NBT trapped within liposomes exposed to xanthine oxidase and hypoxanthine. Nitroblue Tetrazolium 195-198 ceruloplasmin Homo sapiens 64-77 6284006-7 1982 Ceruloplasmin also inhibited reduction of cytochrome c and NBT mediated by the aerobic action of xanthine oxidase on acetaldehyde (another superoxide-generating system) and mimicked the activity of purified human erythrocyte SOD by inhibiting photoreduction of NBT and by accelerating aerobic photooxidation of dianisidine. Nitroblue Tetrazolium 59-62 ceruloplasmin Homo sapiens 0-13 6284006-7 1982 Ceruloplasmin also inhibited reduction of cytochrome c and NBT mediated by the aerobic action of xanthine oxidase on acetaldehyde (another superoxide-generating system) and mimicked the activity of purified human erythrocyte SOD by inhibiting photoreduction of NBT and by accelerating aerobic photooxidation of dianisidine. Nitroblue Tetrazolium 261-264 ceruloplasmin Homo sapiens 0-13 6895053-3 1981 The hydrogen in the NADH generated is transferred by diaphorase (EC 1.6.4.3) to nitrotetrazolium blue to yield diformazan 540 nm). Nitroblue Tetrazolium 80-101 dihydrolipoamide dehydrogenase Homo sapiens 53-63 6975849-2 1981 Mononuclear blood cells, when stimulated with various mitogens, produced DIF, which induced differentiation of HL-60 into phagocytizing nitro blue tetrazolium reducing cells with the morphologic characteristic of granulopoietic or myelomonocytic cells. Nitroblue Tetrazolium 136-158 tumor necrosis factor Homo sapiens 73-76 422251-7 1979 These rather poor results are not surprising if one considers that NBT is only taken up by granulocytes as macrocomplex containing heparin or fibrinogen. Nitroblue Tetrazolium 67-70 fibrinogen beta chain Homo sapiens 142-152 6160210-3 1980 When the NBT stain was combined with the Karnovsky acetylcholinesterase (AChE) procedure the blue-coloured nerve terminal processes were vividly outlined by the brown copper ferrocyanide-AChE reaction product. Nitroblue Tetrazolium 9-12 acetylcholinesterase (Cartwright blood group) Homo sapiens 73-77 6160210-3 1980 When the NBT stain was combined with the Karnovsky acetylcholinesterase (AChE) procedure the blue-coloured nerve terminal processes were vividly outlined by the brown copper ferrocyanide-AChE reaction product. Nitroblue Tetrazolium 9-12 acetylcholinesterase (Cartwright blood group) Homo sapiens 187-191 6160210-9 1980 The powerful experimental advantage of the NBT-AChE stain for neuromuscular junctions resulted from the sharp colour contrast which made possible accurate determinations of the relationship between the presynaptic nerve terminal arborization and the postsynaptic junctional AChE activity. Nitroblue Tetrazolium 43-46 acetylcholinesterase (Cartwright blood group) Homo sapiens 47-51 6160210-9 1980 The powerful experimental advantage of the NBT-AChE stain for neuromuscular junctions resulted from the sharp colour contrast which made possible accurate determinations of the relationship between the presynaptic nerve terminal arborization and the postsynaptic junctional AChE activity. Nitroblue Tetrazolium 43-46 acetylcholinesterase (Cartwright blood group) Homo sapiens 274-278 6160211-2 1980 Presynaptic nerve terminals and postsynaptic acetylcholinesterase (AChE) activity simultaneously demonstrated at these developing junctions using the NBT-AChE method. Nitroblue Tetrazolium 150-153 acetylcholinesterase (Cartwright blood group) Homo sapiens 67-71 6160211-2 1980 Presynaptic nerve terminals and postsynaptic acetylcholinesterase (AChE) activity simultaneously demonstrated at these developing junctions using the NBT-AChE method. Nitroblue Tetrazolium 150-153 acetylcholinesterase (Cartwright blood group) Homo sapiens 154-158 7448746-0 1980 The effect of VP 16-213 on NBT reduction in the normal polymorphonuclear neutrophil. Nitroblue Tetrazolium 27-30 host cell factor C1 Homo sapiens 14-19 7448746-1 1980 VP 16-213, an antineoplastic, semisynthetic podophyllotoxin derivative, inhibits NBT reduction in the polymorphonuclear neutrophil (PMN). Nitroblue Tetrazolium 81-84 host cell factor C1 Homo sapiens 0-5 7448746-5 1980 VP 16-213 may alter normal respiratory function in the PMN as reflected by inhibition of NBT reduction. Nitroblue Tetrazolium 89-92 host cell factor C1 Homo sapiens 0-5 226386-1 1979 The higher superoxide dismutase (SOD) levels found in human blood cells when Nitro Blue Tetrazolium (NBT) rather than Cytochrome C was used as the colorimetric detector of superoxide (O-2) was investigated. Nitroblue Tetrazolium 101-104 immunoglobulin kappa variable 1D-39 Homo sapiens 184-187 396798-3 1979 Togheter NBT and vitamin E blockedaggregation by epinephrine, collagen, and thrombin, but permitted a small first wave stimulated by ADP. Nitroblue Tetrazolium 9-12 coagulation factor II, thrombin Homo sapiens 76-84 475666-1 1979 Leucocytes from purified protein derivative (PPD) skin test positive individuals, after exposure to PPD in vitro, show a significant increase in nitroblue tetrazolium (NBT) dye reduction when compared to leucocytes from PPD negative donors. Nitroblue Tetrazolium 145-166 cellular communication network factor 6 Homo sapiens 45-48 475666-1 1979 Leucocytes from purified protein derivative (PPD) skin test positive individuals, after exposure to PPD in vitro, show a significant increase in nitroblue tetrazolium (NBT) dye reduction when compared to leucocytes from PPD negative donors. Nitroblue Tetrazolium 145-166 cellular communication network factor 6 Homo sapiens 100-103 475666-1 1979 Leucocytes from purified protein derivative (PPD) skin test positive individuals, after exposure to PPD in vitro, show a significant increase in nitroblue tetrazolium (NBT) dye reduction when compared to leucocytes from PPD negative donors. Nitroblue Tetrazolium 145-166 cellular communication network factor 6 Homo sapiens 100-103 475666-1 1979 Leucocytes from purified protein derivative (PPD) skin test positive individuals, after exposure to PPD in vitro, show a significant increase in nitroblue tetrazolium (NBT) dye reduction when compared to leucocytes from PPD negative donors. Nitroblue Tetrazolium 168-171 cellular communication network factor 6 Homo sapiens 45-48 475666-1 1979 Leucocytes from purified protein derivative (PPD) skin test positive individuals, after exposure to PPD in vitro, show a significant increase in nitroblue tetrazolium (NBT) dye reduction when compared to leucocytes from PPD negative donors. Nitroblue Tetrazolium 168-171 cellular communication network factor 6 Homo sapiens 100-103 475666-1 1979 Leucocytes from purified protein derivative (PPD) skin test positive individuals, after exposure to PPD in vitro, show a significant increase in nitroblue tetrazolium (NBT) dye reduction when compared to leucocytes from PPD negative donors. Nitroblue Tetrazolium 168-171 cellular communication network factor 6 Homo sapiens 100-103 486607-4 1979 In measuring SOD activity, the serum factor has a great effect, and serum contains a substance that inhibits NBT reduction. Nitroblue Tetrazolium 109-112 superoxide dismutase 1 Homo sapiens 13-16 916943-10 1977 In comparison between the NBT value and the simultaneously examined ALP it was found that ALP is a more sensitive parameter but that an increased ALP is not indicative of an active stage. Nitroblue Tetrazolium 26-29 ATHS Homo sapiens 90-93 916943-10 1977 In comparison between the NBT value and the simultaneously examined ALP it was found that ALP is a more sensitive parameter but that an increased ALP is not indicative of an active stage. Nitroblue Tetrazolium 26-29 ATHS Homo sapiens 90-93 879276-6 1977 Together NBT and vitamin E blocked aggregation by epinephrine, collagen, and thrombin, but permitted a small first wave stimulated by ADP. Nitroblue Tetrazolium 9-12 coagulation factor II, thrombin Homo sapiens 77-85 1254941-4 1976 Antigenic luteinizing hormone was subsequently localized with hydrogen peroxide-3,3"-diaminobenzidine as substrate for peroxidase, and growth hormone was localized with a glucose-phenazine methosulfate-nitroblue tetrazolium mixture as a substrate for glucose oxidase. Nitroblue Tetrazolium 202-223 gonadotropin releasing hormone receptor Rattus norvegicus 135-149 181277-2 1976 G6PD was localized in the cells of cortical stroma and hilus using a histochemical technique for the reduction of the tetrazolium salt, Nitro-Blue tetrazolium. Nitroblue Tetrazolium 136-158 glucose-6-phosphate dehydrogenase Homo sapiens 0-4 184979-1 1976 The rate of nitrobluetetrazolium reduction by extracts from rodent and human kidney tissue has been measured in the presence and absence of exogeneous superoxide dismutase and catalase. Nitroblue Tetrazolium 12-32 catalase Homo sapiens 176-184 1155373-6 1975 Increased NBT reductions by PMN"s was found when leukocytes were incubated with heparin, CSA, and CSB, but these compounds had no effect on the HMPS activity of PMN"s unless NBT was added. Nitroblue Tetrazolium 10-13 chorionic somatomammotropin hormone 2 Homo sapiens 98-101 1248624-0 1976 Inhibition of nitroblue tetrazolium reduction by cuprein (superoxide dismutase), Cu(tyr)2 and Cu(lys)2. Nitroblue Tetrazolium 14-35 aminoadipate-semialdehyde dehydrogenase Homo sapiens 94-102 5539768-0 1971 Nitroblue tetrazolium dye test as an aid in the differential diagnosis of febrile disorders. Nitroblue Tetrazolium 0-21 activation induced cytidine deaminase Homo sapiens 37-40 4133405-0 1973 [NBT test, a diagnostic aid in differentiation of pathogenetically different leukocytes and febrile diseases]. Nitroblue Tetrazolium 1-4 activation induced cytidine deaminase Homo sapiens 24-27 13974734-2 1963 Succinic dehydrogenase (SDH) was localized in the mitochondria of Sarcoma 37 ascites tumor cells by the use of tetranitro-BT (TNBT) and nitro-BT (NBT) in smear preparations. Nitroblue Tetrazolium 116-124 succinate dehydrogenase complex iron sulfur subunit B Homo sapiens 0-22 4295240-3 1968 LDH activity was maximal at the end of the exponential growth period and was measured spectrophotometrically by reduction of p-nitro-blue tetrazolium, with phenazine methosulfate as a coupling agent. Nitroblue Tetrazolium 125-149 AT695_RS04475 Staphylococcus aureus 0-3 13974734-2 1963 Succinic dehydrogenase (SDH) was localized in the mitochondria of Sarcoma 37 ascites tumor cells by the use of tetranitro-BT (TNBT) and nitro-BT (NBT) in smear preparations. Nitroblue Tetrazolium 116-124 succinate dehydrogenase complex iron sulfur subunit B Homo sapiens 24-27 13974734-2 1963 Succinic dehydrogenase (SDH) was localized in the mitochondria of Sarcoma 37 ascites tumor cells by the use of tetranitro-BT (TNBT) and nitro-BT (NBT) in smear preparations. Nitroblue Tetrazolium 127-130 succinate dehydrogenase complex iron sulfur subunit B Homo sapiens 0-22 13974734-2 1963 Succinic dehydrogenase (SDH) was localized in the mitochondria of Sarcoma 37 ascites tumor cells by the use of tetranitro-BT (TNBT) and nitro-BT (NBT) in smear preparations. Nitroblue Tetrazolium 127-130 succinate dehydrogenase complex iron sulfur subunit B Homo sapiens 24-27 13563553-1 1958 A histochemical method is described for the localization of triphosphopyridine nucleotide diaphorase using a recently synthesized tetrazolium salt (Nitro-BT). Nitroblue Tetrazolium 148-156 dihydrolipoamide dehydrogenase Homo sapiens 90-100 33273578-2 2020 It is thought that the catalytic activity of NOS promotes NADPH-dependent reduction of nitro-blue tetrazolium (NBT) to diformazan. Nitroblue Tetrazolium 87-109 2,4-dienoyl-CoA reductase 1 Homo sapiens 58-63 32935604-5 2021 Our work revealed that the NBT/PMS assay with some modifications can be used to measure the activity of LDH-B and other dehydrogenases in a high-throughput screening format at the early stages of drug discovery. Nitroblue Tetrazolium 27-30 lactate dehydrogenase B Homo sapiens 104-109 33273578-2 2020 It is thought that the catalytic activity of NOS promotes NADPH-dependent reduction of nitro-blue tetrazolium (NBT) to diformazan. Nitroblue Tetrazolium 111-114 2,4-dienoyl-CoA reductase 1 Homo sapiens 58-63 33273578-6 2020 Our results suggest that NADPH diaphorase in aldehyde-fixed tissues is not enzymatic but is due to the presence of NO-containing factors (free SNOs or nitrosated proteins such as NOS), which promote NADPH-dependent reduction of NBT to diformazan. Nitroblue Tetrazolium 228-231 2,4-dienoyl-CoA reductase 1 Homo sapiens 25-30 31442385-3 2019 Using the interaction of recombinant hCD40 ligand with HEK-Blue sensor cells expressing the CD40 receptor as example, we show that such an assay can be developed based on BCIP/NBT (5-bromo-4-chloro-3-indolyl phosphate/nitroblue tetrazolium chloride) as substrate. Nitroblue Tetrazolium 176-179 CD40 molecule Homo sapiens 37-42 32850864-10 2020 The proportions of NBT stained area in the matured oocytes and cumulus cells was found significantly lesser in the control as compared to the IL-7 (1 and 5 ng/ml) treated groups. Nitroblue Tetrazolium 19-22 interleukin 7 Homo sapiens 142-146 32083866-8 2020 Diosmin reduced LPS-induced total ROS production (DCFDA assay) and superoxide anion production (NBT assay and NBT-positive cells). Nitroblue Tetrazolium 96-99 toll-like receptor 4 Mus musculus 16-19 32083866-8 2020 Diosmin reduced LPS-induced total ROS production (DCFDA assay) and superoxide anion production (NBT assay and NBT-positive cells). Nitroblue Tetrazolium 110-113 toll-like receptor 4 Mus musculus 16-19 32850864-13 2020 The NBT staining patterns of the oocytes and cumulus cells following the combined treatment with IL-7 (5 ng/ml) and Tempol (10 and 25 mM) were comparable with that of the control. Nitroblue Tetrazolium 4-7 interleukin 7 Homo sapiens 97-101 32227083-7 2020 NBT staining and pharmacological experiments indicate that ILA induces superoxide formation of the wild type and of an SA-deficient (NahG sid2) line. Nitroblue Tetrazolium 0-3 ILITYHIA Arabidopsis thaliana 59-62 32271339-5 2020 These results indicate that NBT-xCT:Sm3+ piezo-luminescent ceramics show great potential applications in white LEDs, as well as novel optical-electronic multifunctional devices. Nitroblue Tetrazolium 28-31 solute carrier family 7 member 11 Homo sapiens 32-35 31442385-3 2019 Using the interaction of recombinant hCD40 ligand with HEK-Blue sensor cells expressing the CD40 receptor as example, we show that such an assay can be developed based on BCIP/NBT (5-bromo-4-chloro-3-indolyl phosphate/nitroblue tetrazolium chloride) as substrate. Nitroblue Tetrazolium 176-179 CD40 molecule Homo sapiens 38-42 30606139-11 2019 CONCLUSIONS: These results suggest that the Oct4 gene may regulate NBT pathogenic differentiation pathways, and should thus be considered as a target for knockdown when developing novel therapies for high-risk NBT patients. Nitroblue Tetrazolium 67-70 POU class 5 homeobox 1 Homo sapiens 44-48 30431398-8 2019 No differences in heart rate, blood glucose and blood lactate responses were apparent, but overall RPE was higher in NBT compared with BT (17.8 +- 0.9 vs 16.7 +- 0.7 au, p < .05). Nitroblue Tetrazolium 117-120 ribulose-5-phosphate-3-epimerase Homo sapiens 99-102 29702544-3 2018 The CGD patients were diagnosed according to clinical features and biochemical tests, including nitroblue tetrazolium and dihydrorhodamine-1, 2, 3 tests, performed on patients and their mothers. Nitroblue Tetrazolium 96-117 cytochrome b-245 beta chain Homo sapiens 4-7 30289902-8 2018 In deletion PML-RARA-transduced cells, the CD11b expression levels and NBT reducing ability were significantly decreased compared with control cells and the formation of PML nuclear bodies was rarely observed after RA treatment. Nitroblue Tetrazolium 71-74 retinoic acid receptor alpha Homo sapiens 16-20 30289902-8 2018 In deletion PML-RARA-transduced cells, the CD11b expression levels and NBT reducing ability were significantly decreased compared with control cells and the formation of PML nuclear bodies was rarely observed after RA treatment. Nitroblue Tetrazolium 71-74 PML nuclear body scaffold Homo sapiens 12-15 29886170-3 2018 The purified superoxide dismutase was optimally active at pH 9.0 and displayed stability over a broad pH range of 7.0-10.0 and was stable up to 70 C. SOD was localized in polyacrylamide gel by activity staining, based on the reduction of nitroblue tetrazolium (NBT) by superoxide ion. Nitroblue Tetrazolium 239-260 superoxide dismutase Anoxybacillus gonensis 13-33 29886170-3 2018 The purified superoxide dismutase was optimally active at pH 9.0 and displayed stability over a broad pH range of 7.0-10.0 and was stable up to 70 C. SOD was localized in polyacrylamide gel by activity staining, based on the reduction of nitroblue tetrazolium (NBT) by superoxide ion. Nitroblue Tetrazolium 262-265 superoxide dismutase Anoxybacillus gonensis 13-33 29888123-12 2018 We found that PRF in combination with NBT increased beta-EP levels and decreased plasma IL-6 and SP, thereby alleviating pain and hyperalgesia in PHN patients. Nitroblue Tetrazolium 38-41 proopiomelanocortin Homo sapiens 52-59 29888123-12 2018 We found that PRF in combination with NBT increased beta-EP levels and decreased plasma IL-6 and SP, thereby alleviating pain and hyperalgesia in PHN patients. Nitroblue Tetrazolium 38-41 interleukin 6 Homo sapiens 88-99 29445224-7 2018 NBT induced cell cycle arrest in the G0/G1 phase by decreasing the expression of cyclin D1. Nitroblue Tetrazolium 0-3 cyclin D1 Homo sapiens 81-90 29445224-10 2018 The experiments inferred that the combination of NBT and CQ significantly promoted MCF-7 cell mitochondria to divide and Cyt C to be released from mitochondria to the cytoplasm, resulting in an increased apoptosis rate. Nitroblue Tetrazolium 49-52 cytochrome c, somatic Homo sapiens 121-126 29087184-6 2017 The superoxide dismutase (SOD) activities of the Cu2+/Cu2+ and Cu2+/Zn2+ complexes of L1 and L2 have been evaluated using nitro blue tetrazolium assays at pH 7.4. Nitroblue Tetrazolium 122-144 superoxide dismutase 1 Homo sapiens 26-29 29443080-3 2018 It works by soaking the acrylamide or agarose DNA gel in a solution of 1x (equivalent to 2.0 microM) SYBR Green I (SG I) and 0.20 mM nitro blue tetrazolium that produces a purple precipitate of formazan when exposed to sunlight or specifically blue light. Nitroblue Tetrazolium 133-155 semenogelin 1 Homo sapiens 115-119 29594441-5 2017 After exposure to the sample, a substrate for ALP (5-bromo-4-chloro-3-indolyl phosphate/nitro blue tetrazolium) was dropped on the test strip. Nitroblue Tetrazolium 88-110 alkaline phosphatase, placental Homo sapiens 46-49 29087184-6 2017 The superoxide dismutase (SOD) activities of the Cu2+/Cu2+ and Cu2+/Zn2+ complexes of L1 and L2 have been evaluated using nitro blue tetrazolium assays at pH 7.4. Nitroblue Tetrazolium 122-144 L1 cell adhesion molecule Homo sapiens 86-95 28984335-4 2017 The SOD activity was determined by a xanthine-xanthine oxidase-nitro blue tetrazolium assay and the IC50 values were determined to be 1.53 and 2.09 muM, respectively. Nitroblue Tetrazolium 63-85 superoxide dismutase 1 Homo sapiens 4-7 28471113-8 2017 The activating effect and chemotactic activity of HMGN2 on neutrophils were determined using a nitroblue tetrazolium (NBT) reduction assay and Transwell chamber cell migration assay, respectively. Nitroblue Tetrazolium 95-116 high mobility group nucleosomal binding domain 2 Homo sapiens 50-55 28471113-8 2017 The activating effect and chemotactic activity of HMGN2 on neutrophils were determined using a nitroblue tetrazolium (NBT) reduction assay and Transwell chamber cell migration assay, respectively. Nitroblue Tetrazolium 118-121 high mobility group nucleosomal binding domain 2 Homo sapiens 50-55 26628755-9 2015 RESULTS: Significantly impaired phagocytic function as indicated by lower phagocytic, lytic indices and decreased NBT reduction of neutrophils was seen in COPD subjects compared to normal healthy controls (P < .001). Nitroblue Tetrazolium 114-117 COPD Homo sapiens 155-159 27836260-2 2017 Here we develop two chromogenic methods for the detection of glucan phosphatase activity in situ after non denaturing poliacrylamide gel electrophoresis; one method uses pNPP and the second one applies BCIP/NBT. Nitroblue Tetrazolium 207-210 EPM2A glucan phosphatase, laforin Homo sapiens 61-79 26394634-11 2016 We recommend the X-gal/nitroblue tetrazolium staining mixture as the first choice for the detection of beta-galactosidase activity on histological sections. Nitroblue Tetrazolium 23-44 galactosidase, beta 1 Mus musculus 103-121 26232605-7 2015 RESULTS: Increased mRNA expression of VEGF-A, IGF-I, and IGF-IR was significantly higher in TNBC (65.1%, 65.1%, and 72.1%) than non-TNBC (28.1%, 33.96% and 28.3%) and NBT (0.00%) (P<0.001). Nitroblue Tetrazolium 167-170 vascular endothelial growth factor A Homo sapiens 38-44 26232605-7 2015 RESULTS: Increased mRNA expression of VEGF-A, IGF-I, and IGF-IR was significantly higher in TNBC (65.1%, 65.1%, and 72.1%) than non-TNBC (28.1%, 33.96% and 28.3%) and NBT (0.00%) (P<0.001). Nitroblue Tetrazolium 167-170 insulin like growth factor 1 receptor Homo sapiens 57-63 26348407-4 2015 Under physiological conditions, AQP1-/- mice develop normally; however, in the setting of MI, they exhibit cardioprotective properties, as shown by reduced cardiac infarct size determined via NBT staining, improved cardiac function determined via left ventricular catheter measurements, decreased AQP1-dependent myocardial edema determined via water content assays, and decreased apoptosis determined via TUNEL analysis. Nitroblue Tetrazolium 192-195 aquaporin 1 Mus musculus 32-36 28155600-7 2017 In addition, suppression in cytosolic superoxide-dismutase (Cu-Zn isoform/SOD1; NBT reduction-test) and an insufficient protection through catalase activity culminate free radical-related damages. Nitroblue Tetrazolium 80-83 superoxide dismutase 1 Rattus norvegicus 74-78 27173532-2 2016 Superoxide radicals (O2(*-)) and their protonated form (hydroperoxyl radicals, HO2(*)) were detected by the reduction of nitroblue tetrazolium into formazan, and hydroxyl radicals (OH(*)) were detected by the hydroxylation of terephthalate. Nitroblue Tetrazolium 121-142 heme oxygenase 2 Homo sapiens 79-82 27588133-7 2016 Nitroblue tetrazolium (NBT) reduction assays showed decreased NBT reduction activity in the CRT overexpression group and increased NBT reduction in the CRT siRNA group. Nitroblue Tetrazolium 0-21 calreticulin Homo sapiens 92-95 27588133-7 2016 Nitroblue tetrazolium (NBT) reduction assays showed decreased NBT reduction activity in the CRT overexpression group and increased NBT reduction in the CRT siRNA group. Nitroblue Tetrazolium 0-21 calreticulin Homo sapiens 152-155 27588133-7 2016 Nitroblue tetrazolium (NBT) reduction assays showed decreased NBT reduction activity in the CRT overexpression group and increased NBT reduction in the CRT siRNA group. Nitroblue Tetrazolium 62-65 calreticulin Homo sapiens 92-95 27588133-7 2016 Nitroblue tetrazolium (NBT) reduction assays showed decreased NBT reduction activity in the CRT overexpression group and increased NBT reduction in the CRT siRNA group. Nitroblue Tetrazolium 62-65 calreticulin Homo sapiens 92-95 27618921-6 2016 RESULTS: Phagocytosis rate was reduced in antigen treated monocytes whereas nitroblue tetrazolium (NBT) reduction was more in apical membrane antigen-1 (AMA-1) and merozoite surface protein-7 (MSP7) treated than in untreated and von Willebrand factor A domain-related protein (WARP) treated monocytes. Nitroblue Tetrazolium 76-97 von Willebrand factor A domain containing 1 Homo sapiens 229-275 27618921-6 2016 RESULTS: Phagocytosis rate was reduced in antigen treated monocytes whereas nitroblue tetrazolium (NBT) reduction was more in apical membrane antigen-1 (AMA-1) and merozoite surface protein-7 (MSP7) treated than in untreated and von Willebrand factor A domain-related protein (WARP) treated monocytes. Nitroblue Tetrazolium 76-97 von Willebrand factor A domain containing 1 Homo sapiens 277-281 27618921-6 2016 RESULTS: Phagocytosis rate was reduced in antigen treated monocytes whereas nitroblue tetrazolium (NBT) reduction was more in apical membrane antigen-1 (AMA-1) and merozoite surface protein-7 (MSP7) treated than in untreated and von Willebrand factor A domain-related protein (WARP) treated monocytes. Nitroblue Tetrazolium 99-102 von Willebrand factor A domain containing 1 Homo sapiens 229-275 27618921-6 2016 RESULTS: Phagocytosis rate was reduced in antigen treated monocytes whereas nitroblue tetrazolium (NBT) reduction was more in apical membrane antigen-1 (AMA-1) and merozoite surface protein-7 (MSP7) treated than in untreated and von Willebrand factor A domain-related protein (WARP) treated monocytes. Nitroblue Tetrazolium 99-102 von Willebrand factor A domain containing 1 Homo sapiens 277-281 26896642-5 2016 PDI"s inhibitors bacitracin and nitroblue tetrazolium reduced the percent of infected cells and small amounts of recTgPDI proteins interfered with the invasion step. Nitroblue Tetrazolium 32-53 protein disulfide isomerase family A member 2 Homo sapiens 0-3 26407339-6 2016 Our results show that FOE reports were strongly correlated with arithmetic errors and numerical properties of the NBT, suggesting that the FOE accurately represents the error. Nitroblue Tetrazolium 114-117 WAPL cohesin release factor Homo sapiens 22-25 26407339-6 2016 Our results show that FOE reports were strongly correlated with arithmetic errors and numerical properties of the NBT, suggesting that the FOE accurately represents the error. Nitroblue Tetrazolium 114-117 WAPL cohesin release factor Homo sapiens 139-142 22969967-7 2012 The results of the NBT reduction test and CD11b antigen detection by FCM indicated that IFN-gamma induces the differentiation of NB4 and NB4-R1 cells to some extent. Nitroblue Tetrazolium 19-22 interferon gamma Homo sapiens 88-97 26207760-6 2015 Myoadenylate deaminase (MAD) activity was determined using p-nitro blue tetrazolium staining in muscle cryostat sections. Nitroblue Tetrazolium 59-83 adenosine monophosphate deaminase 3 Homo sapiens 0-22 26207760-6 2015 Myoadenylate deaminase (MAD) activity was determined using p-nitro blue tetrazolium staining in muscle cryostat sections. Nitroblue Tetrazolium 59-83 adenosine monophosphate deaminase 3 Homo sapiens 24-27 24357020-7 2014 Treatment with an inhibitor of ERK (PD98059) blocked the nitrotetrazolium blue chloride (NBT) reducing activity and CD11b expression in the N. chinensis-treated HL-60 cells, whereas treatment with an inhibitor of p38 MAPK (SB203580) had no significant effect on NBT reducing activity and CD11b expression. Nitroblue Tetrazolium 57-87 mitogen-activated protein kinase 1 Homo sapiens 31-34 24357020-7 2014 Treatment with an inhibitor of ERK (PD98059) blocked the nitrotetrazolium blue chloride (NBT) reducing activity and CD11b expression in the N. chinensis-treated HL-60 cells, whereas treatment with an inhibitor of p38 MAPK (SB203580) had no significant effect on NBT reducing activity and CD11b expression. Nitroblue Tetrazolium 89-92 mitogen-activated protein kinase 1 Homo sapiens 31-34 24357020-7 2014 Treatment with an inhibitor of ERK (PD98059) blocked the nitrotetrazolium blue chloride (NBT) reducing activity and CD11b expression in the N. chinensis-treated HL-60 cells, whereas treatment with an inhibitor of p38 MAPK (SB203580) had no significant effect on NBT reducing activity and CD11b expression. Nitroblue Tetrazolium 262-265 mitogen-activated protein kinase 1 Homo sapiens 31-34 24288134-10 2014 Redox reactions induced by DA/Cu2+ were observed in multimer regions of alpha-synuclein oligomers through NBT assay. Nitroblue Tetrazolium 106-109 synuclein alpha Homo sapiens 72-87 22750339-5 2012 Synthesized complexes have been tested for their SOD mimic activity using NBT/NADH/PMS system. Nitroblue Tetrazolium 74-77 superoxide dismutase 1 Homo sapiens 49-52 25737734-10 2015 Treatment with 4ME led to significant induction of NBT-reducing activity of PMA stimulated THP-1 cells and upregulation expression of differentiation-associated surface antigen CD11b. Nitroblue Tetrazolium 51-54 GLI family zinc finger 2 Homo sapiens 91-96 24563327-10 2014 Further investigation showed that cytoplasm TARBP2 expression in non-TNBC was higher than that of their adjacent normal breast tissues (NBT), and TNBC was the highest of the three groups. Nitroblue Tetrazolium 136-139 TARBP2 subunit of RISC loading complex Homo sapiens 44-50 24563327-11 2014 The positive expression of cytoplasm TARBP2 in stage III breast cancer, stage I-II breast cancer, and NBT decreased gradually. Nitroblue Tetrazolium 102-105 TARBP2 subunit of RISC loading complex Homo sapiens 37-43 24175985-2 2014 METHODS: Glycation of nail proteins was assessed using a modified photometric nitroblue tetrazolium-based assay, which provides information about average glucose values of the last 6-9 months. Nitroblue Tetrazolium 78-99 CD244 molecule Homo sapiens 22-26 23395717-9 2013 Inhibition of ERK activation using PD98059 significantly decreased NBT+HL60 cells induced by XC treatment. Nitroblue Tetrazolium 67-70 mitogen-activated protein kinase 1 Homo sapiens 14-17 23888688-9 2013 HL-60 cells became more mature in morphology after transfected to HDAC1 siRNA at a concentration of 30-60 nmol x L(-1) for 24 h. NBT reduction ability of HDAC1 siRNA with 30 nmol x L(-1) was 0.31 +/- 0.09, compared with negative control (0.20 +/- 0.02) (t = -3.1, P < 0.01), and with 60 nmol x L(-1) was 0.25 +/- 0.02 in comparison with negative control (0.21 +/- 0.04) (t = -2.12, P < 0.05). Nitroblue Tetrazolium 129-132 histone deacetylase 1 Homo sapiens 66-71 23888688-9 2013 HL-60 cells became more mature in morphology after transfected to HDAC1 siRNA at a concentration of 30-60 nmol x L(-1) for 24 h. NBT reduction ability of HDAC1 siRNA with 30 nmol x L(-1) was 0.31 +/- 0.09, compared with negative control (0.20 +/- 0.02) (t = -3.1, P < 0.01), and with 60 nmol x L(-1) was 0.25 +/- 0.02 in comparison with negative control (0.21 +/- 0.04) (t = -2.12, P < 0.05). Nitroblue Tetrazolium 129-132 histone deacetylase 1 Homo sapiens 154-159 23456281-4 2013 The generation of superoxides during the oxidation of phenylhydrazine by tyrosinase was monitored by nitroblue tetrazolium (NBT) assay. Nitroblue Tetrazolium 101-122 tyrosinase Homo sapiens 73-83 23456281-4 2013 The generation of superoxides during the oxidation of phenylhydrazine by tyrosinase was monitored by nitroblue tetrazolium (NBT) assay. Nitroblue Tetrazolium 124-127 tyrosinase Homo sapiens 73-83 23490067-5 2013 Furthermore, activation of extracellular-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) by TPA+AA was identified in HL-60 cells, and the ERK inhibitor, PD98059, but not the JNK inhibitor, SP600125, inhibited TPA+AA-induced NBT-positive cells. Nitroblue Tetrazolium 233-236 mitogen-activated protein kinase 1 Homo sapiens 27-57 23490067-5 2013 Furthermore, activation of extracellular-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) by TPA+AA was identified in HL-60 cells, and the ERK inhibitor, PD98059, but not the JNK inhibitor, SP600125, inhibited TPA+AA-induced NBT-positive cells. Nitroblue Tetrazolium 233-236 mitogen-activated protein kinase 1 Homo sapiens 59-62 23490067-5 2013 Furthermore, activation of extracellular-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) by TPA+AA was identified in HL-60 cells, and the ERK inhibitor, PD98059, but not the JNK inhibitor, SP600125, inhibited TPA+AA-induced NBT-positive cells. Nitroblue Tetrazolium 233-236 mitogen-activated protein kinase 8 Homo sapiens 68-91 23490067-5 2013 Furthermore, activation of extracellular-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) by TPA+AA was identified in HL-60 cells, and the ERK inhibitor, PD98059, but not the JNK inhibitor, SP600125, inhibited TPA+AA-induced NBT-positive cells. Nitroblue Tetrazolium 233-236 mitogen-activated protein kinase 8 Homo sapiens 93-96 22947512-5 2012 Pharmacological approach using mammalian NOS inhibitors, NBT (300 muM) and l-NAME (5 mM), showed significant inhibition (100% and 67% respectively) supporting that the BjNOSla operates via the oxidative pathway. Nitroblue Tetrazolium 57-60 latexin Homo sapiens 66-69 22676437-10 2012 CONCLUSIONS: ALP expression detected using BCIP/NBT substrate applied to previously stained cells is useful in differentiating canine OSA from other mesenchymal neoplasms. Nitroblue Tetrazolium 48-51 alkaline phosphatase, biomineralization associated Canis lupus familiaris 13-16 22437533-5 2012 Using nitroblue tetrazolium and hydrogen peroxide assays, we showed that sugar ligand-bound conglutinin stimulated the production of superoxide and H2O2 in granulocytes whereas the non-sugar-bound form of conglutinin inhibited these processes. Nitroblue Tetrazolium 6-27 conglutinin Bos taurus 92-103 22143245-15 2011 Those cells with dysfunctional COX will therefore not be saturated by the DAB product, allowing for the visualization of SDH activity by reduction of nitroblue tetrazolium (NBT), an electron acceptor, to a blue formazan end product (9,24). Nitroblue Tetrazolium 150-171 succinate dehydrogenase complex iron sulfur subunit B Homo sapiens 121-124 22101193-5 2012 In the present study, we developed and validated an in situ PREP intracellular activity assay in primary rat cortical neurons, using nitroblue tetrazolium chloride salt (NBT) and a PREP specific substrate (S)-benzyl 2-(2-(4-hydroxynaphthalen-l-ylcarbanoyl)pyrrolidin-l-yl)-2-oxoethylcarbamate (UAMC-00682). Nitroblue Tetrazolium 170-173 prolyl endopeptidase Rattus norvegicus 60-64 22085718-3 2011 Upon gene silencing of PCGF2 with lentiviral short hairpin RNA, granulocytic differentiation was induced as assessed by differentiation marker gene expression, nitroblue tetrazolium staining, Wright-Giemsa staining, and cell cycle analysis. Nitroblue Tetrazolium 160-181 polycomb group ring finger 2 Homo sapiens 23-28 22143245-15 2011 Those cells with dysfunctional COX will therefore not be saturated by the DAB product, allowing for the visualization of SDH activity by reduction of nitroblue tetrazolium (NBT), an electron acceptor, to a blue formazan end product (9,24). Nitroblue Tetrazolium 173-176 succinate dehydrogenase complex iron sulfur subunit B Homo sapiens 121-124 20583870-2 2011 The superoxide dismutase (SOD) like activity of the complexes were measured using an NBT/NADH/PMS system, these were expressed in terms of the concentration of complex which termianates the formation of formazan by 50% (IC50 value) and found to range from 0.781 to 1.354 muM. Nitroblue Tetrazolium 85-88 superoxide dismutase 1 Homo sapiens 4-24 20583870-2 2011 The superoxide dismutase (SOD) like activity of the complexes were measured using an NBT/NADH/PMS system, these were expressed in terms of the concentration of complex which termianates the formation of formazan by 50% (IC50 value) and found to range from 0.781 to 1.354 muM. Nitroblue Tetrazolium 85-88 superoxide dismutase 1 Homo sapiens 26-29 21086135-7 2010 In addition, in cells induced to differentiate by ATRA or VD3, Nitroblue-tetrazolium (NBT) reduction and esterase activity, were blocked either by LY294002, a PI3K inhibitor, or by BIM, a PKC inhibitor, without affecting cell surface markers such as CD11b or CD14. Nitroblue Tetrazolium 63-84 protein kinase C alpha Homo sapiens 188-191 21086135-7 2010 In addition, in cells induced to differentiate by ATRA or VD3, Nitroblue-tetrazolium (NBT) reduction and esterase activity, were blocked either by LY294002, a PI3K inhibitor, or by BIM, a PKC inhibitor, without affecting cell surface markers such as CD11b or CD14. Nitroblue Tetrazolium 86-89 protein kinase C alpha Homo sapiens 188-191 21086135-7 2010 In addition, in cells induced to differentiate by ATRA or VD3, Nitroblue-tetrazolium (NBT) reduction and esterase activity, were blocked either by LY294002, a PI3K inhibitor, or by BIM, a PKC inhibitor, without affecting cell surface markers such as CD11b or CD14. Nitroblue Tetrazolium 86-89 integrin subunit alpha M Homo sapiens 250-255 21086135-7 2010 In addition, in cells induced to differentiate by ATRA or VD3, Nitroblue-tetrazolium (NBT) reduction and esterase activity, were blocked either by LY294002, a PI3K inhibitor, or by BIM, a PKC inhibitor, without affecting cell surface markers such as CD11b or CD14. Nitroblue Tetrazolium 86-89 CD14 molecule Homo sapiens 259-263 21086135-8 2010 Intriguingly, the silencing of Rictor by its siRNA also suppressed the reducing ability of NBT following VD3-induced cell differentiation. Nitroblue Tetrazolium 91-94 RPTOR independent companion of MTOR complex 2 Homo sapiens 31-37 19907057-9 2010 The nitro blue tetrazolium reduction assay shows that INH is activated by the reaction of LPO-H(2)O(2) with INH. Nitroblue Tetrazolium 4-26 lactoperoxidase Bos taurus 90-93 20878073-4 2010 Immunohistochemical analysis in 172 cases of breast tissues showed that the positive rate of CacyBP protein expression in normal breast tissues (NBT) (89.3%) was higher than that in invasive ductal carcinoma (IDC) (56.1%) (P<0.05). Nitroblue Tetrazolium 145-148 calcyclin binding protein Homo sapiens 93-99 20889731-0 2010 The quassinoid derivative NBT-272 targets both the AKT and ERK signaling pathways in embryonal tumors. Nitroblue Tetrazolium 26-29 AKT serine/threonine kinase 1 Homo sapiens 51-54 20889731-5 2010 These findings also suggested that the depleting effect of NBT-272 on MYC protein expression occurred via indirect mechanisms, rather than selective inhibition. Nitroblue Tetrazolium 59-62 MYC proto-oncogene, bHLH transcription factor Homo sapiens 70-73 20400306-2 2010 The SOD-like activity of parent ligands and complexes were determined by the inhibition of nitroblue tetrazolium (NBT) reduction method, using xanthine/xanthine oxidase as the superoxide radical generator. Nitroblue Tetrazolium 91-112 superoxide dismutase 1 Homo sapiens 4-7 20400306-2 2010 The SOD-like activity of parent ligands and complexes were determined by the inhibition of nitroblue tetrazolium (NBT) reduction method, using xanthine/xanthine oxidase as the superoxide radical generator. Nitroblue Tetrazolium 114-117 superoxide dismutase 1 Homo sapiens 4-7 20137124-5 2010 The alteration of NB4R2 cell differentiation with the interference of pkm2 gene was also validated by nitroblue tetrazolium (NBT) reduction test. Nitroblue Tetrazolium 102-123 pyruvate kinase M1/2 Homo sapiens 70-74 20137124-5 2010 The alteration of NB4R2 cell differentiation with the interference of pkm2 gene was also validated by nitroblue tetrazolium (NBT) reduction test. Nitroblue Tetrazolium 125-128 pyruvate kinase M1/2 Homo sapiens 70-74 20649094-2 2010 The present study is designed to compare and correlate modified NBT reduction method for the estimation of Glycated protein (Glycated Haemoglobin) with HbA1C estimated on DCA+2000Analyzer. Nitroblue Tetrazolium 64-67 hemoglobin subunit alpha 1 Homo sapiens 152-156 17315258-1 2007 Mammalian mitochondrial dihydrolipoamide dehydrogenase (DLDH, EC 1.8.1.4) catalyzes NAD(+)-dependent oxidation of dihydrolipoamide in vivo and can also act as a diaphorase catalyzing in vitro nicotinamide adenine dinucleotide (reduced form) (NADH)-dependent reduction of electron-accepting molecules such as ubiquinone and nitroblue tetrazolium (NBT). Nitroblue Tetrazolium 323-344 dihydrolipoamide dehydrogenase Homo sapiens 56-60 19349119-3 2009 In this study the polyacrylamide gel electrophoresis (PAGE) and nitroblue tetrazolium (NBT) photoreduction methods were used to analyze the effects of GSNO on the activities of lactate dehydrogenase (LDH), glucose-6-phosphate dehydrogenase (G6PD), aconitase and superoxide dismutase (SOD). Nitroblue Tetrazolium 64-85 ETH_00005300 Eimeria tenella 200-203 19349119-3 2009 In this study the polyacrylamide gel electrophoresis (PAGE) and nitroblue tetrazolium (NBT) photoreduction methods were used to analyze the effects of GSNO on the activities of lactate dehydrogenase (LDH), glucose-6-phosphate dehydrogenase (G6PD), aconitase and superoxide dismutase (SOD). Nitroblue Tetrazolium 87-90 ETH_00005300 Eimeria tenella 177-198 18469441-8 2008 AT1R activation-mediated oxidative stress was assessed by changes in NADPH oxidase expression, and the level of superoxide production was determined by nitroblue tetrazolium (NBT) assay. Nitroblue Tetrazolium 175-178 angiotensin II receptor, type 1b Rattus norvegicus 0-4 18407056-2 2008 The PCR-RFLP technique was applied to analyze the correlation between the polymorphisms of Nramp1 gene and immune function [value of Polymorphonuclear Leukocytes (PMN) obtained by Nitroblue Tetrazolium (NBT) Reduction and effect of Cytotoxin in Monocyte] and production performance in 165 Large White pigs. Nitroblue Tetrazolium 180-201 natural resistance associated-macrophage protein 1 Sus scrofa 91-97 18407056-2 2008 The PCR-RFLP technique was applied to analyze the correlation between the polymorphisms of Nramp1 gene and immune function [value of Polymorphonuclear Leukocytes (PMN) obtained by Nitroblue Tetrazolium (NBT) Reduction and effect of Cytotoxin in Monocyte] and production performance in 165 Large White pigs. Nitroblue Tetrazolium 203-206 natural resistance associated-macrophage protein 1 Sus scrofa 91-97 17884519-3 2007 SOD activity was measured by the method based on nitrobluetetrazolium reduction rate. Nitroblue Tetrazolium 49-69 superoxide dismutase 1 Homo sapiens 0-3 17501721-10 2007 Thus NOX4 probably generates O(2)(-) within an intracellular compartment that is accessible to NBT (Nitro Blue Tetrazolium), but not to DHE or ACP. Nitroblue Tetrazolium 95-98 NADPH oxidase 4 Homo sapiens 5-9 17501721-10 2007 Thus NOX4 probably generates O(2)(-) within an intracellular compartment that is accessible to NBT (Nitro Blue Tetrazolium), but not to DHE or ACP. Nitroblue Tetrazolium 100-122 NADPH oxidase 4 Homo sapiens 5-9 20113600-4 2009 G-6-PD activities were measured using the NBT method. Nitroblue Tetrazolium 42-45 glucose-6-phosphate dehydrogenase Homo sapiens 0-6 19181672-1 2009 We recently identified the X-chromosomal four and a half LIM domain gene FHL1 as the causative gene for reducing body myopathy, a disorder characterized by progressive weakness and intracytoplasmic aggregates in muscle that exert reducing activity on menadione nitro-blue-tetrazolium (NBT). Nitroblue Tetrazolium 285-288 four and a half LIM domains 1 Homo sapiens 73-77 18300502-3 2007 RESULTS: The morphological changes showed cell differentiation characteristics; NBT reductant was significantly increased, and the number of NBT positive cells were related to dose of SPGL (in dose-dependent manner); Expression of CD11b and CD14 increased obviously. Nitroblue Tetrazolium 141-144 integrin subunit alpha M Homo sapiens 231-236 17315258-1 2007 Mammalian mitochondrial dihydrolipoamide dehydrogenase (DLDH, EC 1.8.1.4) catalyzes NAD(+)-dependent oxidation of dihydrolipoamide in vivo and can also act as a diaphorase catalyzing in vitro nicotinamide adenine dinucleotide (reduced form) (NADH)-dependent reduction of electron-accepting molecules such as ubiquinone and nitroblue tetrazolium (NBT). Nitroblue Tetrazolium 346-349 dihydrolipoamide dehydrogenase Homo sapiens 56-60 17254356-5 2007 In neuroblastoma--an embryonal tumor with biological similarities to MB--the quassinoid NBT-272 has been demonstrated to inhibit cellular proliferation and to down-regulate c-MYC protein expression. Nitroblue Tetrazolium 88-92 MYC proto-oncogene, bHLH transcription factor Homo sapiens 173-178 17286914-4 2007 The effects of TBP and TRBP on the functions of human monocytes activated by TNF-alpha and IFN-gamma in vitro were detected by nitrotetrazolium blue chloride (NBT) reduction assay for evaluating respiratory burst and by RT-PCR for evaluating IL-1beta and IL-8 mRNA transcription. Nitroblue Tetrazolium 127-157 tumor necrosis factor Homo sapiens 77-86 17286914-4 2007 The effects of TBP and TRBP on the functions of human monocytes activated by TNF-alpha and IFN-gamma in vitro were detected by nitrotetrazolium blue chloride (NBT) reduction assay for evaluating respiratory burst and by RT-PCR for evaluating IL-1beta and IL-8 mRNA transcription. Nitroblue Tetrazolium 127-157 interferon gamma Homo sapiens 91-100 17286914-4 2007 The effects of TBP and TRBP on the functions of human monocytes activated by TNF-alpha and IFN-gamma in vitro were detected by nitrotetrazolium blue chloride (NBT) reduction assay for evaluating respiratory burst and by RT-PCR for evaluating IL-1beta and IL-8 mRNA transcription. Nitroblue Tetrazolium 159-162 interferon gamma Homo sapiens 91-100 18217407-9 2007 RESULTS: It was found that granulocyte-colony stimulating factor activates phagocytic functions of neutrophils by normalizing low values of phagocytic index and number of granulocytes, reducing dye nitroblue tetrazolium reduction and increasing the number of phagocytic cells. Nitroblue Tetrazolium 198-219 colony stimulating factor 3 Homo sapiens 27-64 17504458-6 2007 Exogenous CaCl2 increased NBT reduction at the pollen tube tip, suggesting that Ca2+ increases the activity of pollen NOX in vivo. Nitroblue Tetrazolium 26-29 respiratory burst oxidase homolog protein A-like Nicotiana tabacum 118-121 16809015-6 2006 Additionally, PYY (10(-6)M) decreases NBT reduction in macrophages from 3 and 8 months old rats, and suppresses NO production in cells from 24 months old rats, albeit regardless of absence of in vivo effect of PYY on inflammation in aged rats. Nitroblue Tetrazolium 38-41 peptide YY Rattus norvegicus 14-17 16763214-4 2006 Inhibition of cross-linking activity of TG2 by monodansylcadaverin in these cells led to diminished nitroblue tetrazolium (NBT) positivity, production of less superoxide anion, and decreased expression of GP91PHOX, the membrane-associated subunit of NADPH oxidase. Nitroblue Tetrazolium 100-121 transglutaminase 2, C polypeptide Mus musculus 40-43 16763214-4 2006 Inhibition of cross-linking activity of TG2 by monodansylcadaverin in these cells led to diminished nitroblue tetrazolium (NBT) positivity, production of less superoxide anion, and decreased expression of GP91PHOX, the membrane-associated subunit of NADPH oxidase. Nitroblue Tetrazolium 123-126 transglutaminase 2, C polypeptide Mus musculus 40-43 16763214-5 2006 Neutrophils isolated from TG2(-/-) mice showed diminished NBT reduction capacity, reduced superoxide anion formation, and down-regulation of the gp91phox subunit of NADPH oxidase, compared with wild-type cells. Nitroblue Tetrazolium 58-61 transglutaminase 2, C polypeptide Mus musculus 26-29 16861049-7 2007 In addition, the vasoconstrictor actions of AVP and phenylephrine were markedly suppressed after administration of PHMBA or nitroblue tetrazolium. Nitroblue Tetrazolium 124-145 arginine vasopressin Rattus norvegicus 44-47 16650894-5 2006 When cells were treated with realgar in the presence of an inhibitor of PP1 and 2A or an inhibitor of PP2B, the differentiation of the cells was partially suppressed as revealed by NBT reduction assay and the expression of CD14. Nitroblue Tetrazolium 181-184 neuropeptide Y receptor Y4 Homo sapiens 72-75 16885501-8 2006 JAK2 inhibitor suppressed induction of NBT-reducing activity in ML-1 cells treated with both reagents. Nitroblue Tetrazolium 39-42 Janus kinase 2 Homo sapiens 0-4 16513102-3 2006 METHODS: We adapted the nitroblue tetrazolium assay to measure in micro-well plates the fructosamine content of transferrin isolated from serum by immunocomplexation. Nitroblue Tetrazolium 24-45 transferrin Homo sapiens 112-123 16513102-8 2006 CONCLUSIONS: These results indicate that the adapted nitroblue tetrazolium assay combined with immunocomplexation of serum transferrin is suitable to detect differences in in vivo transferrin glycation between non-diabetic, type 1 and type 2 diabetic subjects. Nitroblue Tetrazolium 53-74 transferrin Homo sapiens 180-191 16824780-6 2006 The induction of nitroblue tetrazolium reduction and adhesion abilities in THP-1 cells was closely correlated with the concentrations of interleukin-6 protein in the culture supernatants. Nitroblue Tetrazolium 17-38 interleukin 6 Homo sapiens 137-150 16677835-8 2006 Based on cell morphology and NBT reduction, Tbeta4 and AcSDKP induced differentiation of HL-60 cells. Nitroblue Tetrazolium 29-32 thymosin beta 4 X-linked Homo sapiens 44-50 16595161-2 2006 The expression of heat shock protein was measured using a secreted alkaline phosphatase (SEAP) reporter gene transformed into HeLa cell strain, the levels of superoxide anion (O(2)(-)) and hydrogen peroxide (H(2)O(2)) were determined by NBT reduction assay and DCFH staining flow cytometry (FCM), respectively. Nitroblue Tetrazolium 237-240 heat shock protein 90 beta family member 2, pseudogene Homo sapiens 18-36 16800923-10 2006 Various concentrations (50, 75, 100 microg/ml) of bestatin combined with 10 nmol/L ATRA down-regulated the expression of c-Myc protein, which was negatively correlated with the NBT reduction activity of NB4 cells induced by 10 nmol/L ATRA alone or plus bestatin at various concentrations (r = -0.940, P = 0.017). Nitroblue Tetrazolium 177-180 MYC proto-oncogene, bHLH transcription factor Homo sapiens 121-126 16573735-5 2006 The combined treatment of the cells with PPARgamma ligand and all-trans retinoic acid (ATRA) synergistically induced myelocytic differentiation, as determined by nitroblue tetrazolium reducing ability and cell morphology. Nitroblue Tetrazolium 162-183 peroxisome proliferator activated receptor gamma Homo sapiens 41-50 16129031-8 2005 This rapid down-regulation of VEGF gene expression, during ATRA-induced NB4 cell differentiation, was accompanied by the up-regulation of CD11b expression and an increased NBT reduction rate. Nitroblue Tetrazolium 172-175 vascular endothelial growth factor A Homo sapiens 30-34 16468360-8 2005 SDS-PAGE showed that the target protein rhSOD (19 kD) was purified homogeneously and NBT activity identification proved that the purified and renatured rhSOD had very strong SOD activity. Nitroblue Tetrazolium 85-88 superoxide dismutase 1 Homo sapiens 42-45 16142418-3 2005 In three types of SSs, monophasic fibrous, biphasic and poorly differentiated, NBT/BCIP signals corresponding to SYT-SSX mRNA were uniformly and predominantly positive in the sarcoma cell cytoplasm. Nitroblue Tetrazolium 79-82 synaptotagmin 1 Homo sapiens 113-116 16142418-3 2005 In three types of SSs, monophasic fibrous, biphasic and poorly differentiated, NBT/BCIP signals corresponding to SYT-SSX mRNA were uniformly and predominantly positive in the sarcoma cell cytoplasm. Nitroblue Tetrazolium 79-82 SSX family member 2B Homo sapiens 117-120 16532971-2 2005 METHODS: G6PD deficiency was screened by NBT method, G6PD mutations identified by amplification refractory mutation system (ARMS), mismatch-PCR with a restriction endonuclease, PCR-SSCP and DNA sequencing. Nitroblue Tetrazolium 41-44 glucose-6-phosphate dehydrogenase Homo sapiens 9-13 16410947-6 2005 A trend towards a positive correlation was noted, with increasing percentage of NBT positive neutrophils and levels of IFN-gamma. Nitroblue Tetrazolium 80-83 interferon gamma Homo sapiens 119-128 16410947-7 2005 The high IFN-gamma producing HTLV-1 patient group had significantly greater NBT than healthy controls, 43+/-24% and 17+/-4.8% respectively (p< 0.001), while no significant difference was observed between healthy controls and the low IFN-gamma-producing HTLV-1 patient group (30+/-20%). Nitroblue Tetrazolium 76-79 interferon gamma Homo sapiens 9-18 16422374-6 2005 GCD was suggested and confirmed by the NBT test. Nitroblue Tetrazolium 39-42 guanylate cyclase 2E, pseudogene Homo sapiens 0-3 16316409-8 2005 As CRABPI was elevated far more than any other genes, we observed that the retinoids, all-trans retinoic acid and 9-cis retinoic acid, that bind CRABPI, promoted nitroblue tetrazolium-associated functional cell differentiation in p75NTR PC-3 cells, but not in neo control PC-3 cells. Nitroblue Tetrazolium 162-183 cellular retinoic acid binding protein 1 Homo sapiens 3-9 16316409-8 2005 As CRABPI was elevated far more than any other genes, we observed that the retinoids, all-trans retinoic acid and 9-cis retinoic acid, that bind CRABPI, promoted nitroblue tetrazolium-associated functional cell differentiation in p75NTR PC-3 cells, but not in neo control PC-3 cells. Nitroblue Tetrazolium 162-183 cellular retinoic acid binding protein 1 Homo sapiens 145-151 16316409-8 2005 As CRABPI was elevated far more than any other genes, we observed that the retinoids, all-trans retinoic acid and 9-cis retinoic acid, that bind CRABPI, promoted nitroblue tetrazolium-associated functional cell differentiation in p75NTR PC-3 cells, but not in neo control PC-3 cells. Nitroblue Tetrazolium 162-183 nerve growth factor receptor Homo sapiens 230-236 16081252-5 2005 Incubation of SDS-PAGE gel with BCIP/NBT dye clearly showed that the expression of ALP in tumor renal BBM was markedly reduced as compared to normal kidney. Nitroblue Tetrazolium 37-40 ATHS Homo sapiens 83-86 15738610-7 2005 Nitroblue tetrazolium dye test was used for G6PD deficiency screening and quantitative assay for measurement of G6PD enzyme activity. Nitroblue Tetrazolium 0-21 glucose-6-phosphate dehydrogenase Homo sapiens 44-48 15750262-5 2004 Treatment with genistein also remarkably reduced the Ang II-induced superoxide by the reduction of nitroblue tetrazolium, inhibited nitrotyrosine formation, and attenuated endothelin-1 production by ELISA via the stimulation of Ang II. Nitroblue Tetrazolium 99-120 angiotensinogen Rattus norvegicus 53-59 15476381-11 2004 The complexes exhibit high SOD activity, as shown by the low IC(50) values obtained with the xanthine/xanthine oxidase/NBT assay: 0.13 microM for compound 1; 0.17 microM for compound 2. Nitroblue Tetrazolium 119-122 superoxide dismutase 1 Homo sapiens 27-30 15711098-5 2005 METHODS: The total plasma SOD activity was determined by the nitroblue tetrazolium method, plasma SOD contents by ELISA, and SOD mRNA levels in leukocytes by RT-PCR. Nitroblue Tetrazolium 61-82 superoxide dismutase 1 Homo sapiens 26-29 15634573-5 2004 When ATRA + SQ22536 group compared with ATRA group, the positivity of CD11b decreased from (95.9 +/- 2.5)% to (60.3 +/- 7.1)%, while the A(540) in NBT reduction assay decreased from 0.585 +/- 0.092 to 0.170 +/- 0.028 (P < 0.05). Nitroblue Tetrazolium 147-150 integrin subunit alpha M Homo sapiens 70-75 15634573-7 2004 When ATRA + forskolin group compared with ATRA group, the positivity of CD11b increased from (34.3 +/- 5.3)% to (94.6 +/- 2.4)%, while the A(540) in NBT reduction assay increased from 0.110 +/- 0.028 to 0.395 +/- 0.049 (P < 0.05). Nitroblue Tetrazolium 149-152 integrin subunit alpha M Homo sapiens 72-77 14718401-5 2004 Myocardial ET-1 peptide levels were significantly increased in binary transgenic (BT, ET+/tTA+) compared with nonbinary transgenic (NBT, ET+/tTA-; ET-/tTA+; ET-/tTA-) or DOX-treated BT littermates (40.1+/-4.7 versus 2.6+/-1.2 fmol/mL, P<0.003). Nitroblue Tetrazolium 132-135 endothelin 1 Mus musculus 11-15 15129738-3 2004 SOD activity was evaluated by both the nitroblue tetrazolium (NBT) reduction assay and electron paramagnetic resonance (EPR) with 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) as a spin trapping agent. Nitroblue Tetrazolium 39-60 superoxide dismutase 1 Homo sapiens 0-3 15129738-3 2004 SOD activity was evaluated by both the nitroblue tetrazolium (NBT) reduction assay and electron paramagnetic resonance (EPR) with 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) as a spin trapping agent. Nitroblue Tetrazolium 62-65 superoxide dismutase 1 Homo sapiens 0-3 14712293-5 2004 Phenotypic characterization of the clones revealed that BCR/ABL induces a slight decrease in the proliferation and viability, without a marked effect on cell cycle distribution, the rate of apoptosis or on cellular differentiation, as judged by several cell surface markers and capacity to reduce nitro blue tetrazolium. Nitroblue Tetrazolium 297-319 ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens 56-63 14732485-4 2004 The transient decrease in the nuclear PARG activity by TPA treatment was accompanied by differentiation as measured by the nitroblue tetrazolium (NBT) reducing activity and adhesion to the culture dishes. Nitroblue Tetrazolium 123-144 poly(ADP-ribose) glycohydrolase Homo sapiens 38-42 14732485-4 2004 The transient decrease in the nuclear PARG activity by TPA treatment was accompanied by differentiation as measured by the nitroblue tetrazolium (NBT) reducing activity and adhesion to the culture dishes. Nitroblue Tetrazolium 146-149 poly(ADP-ribose) glycohydrolase Homo sapiens 38-42 12951068-3 2003 Computer-assisted morphometry of the ischaemic reperfused hearts stained with nitroblue tetrazolium showed the extension of damaged myocardium (area at risk and infarct size) significantly reduced in rats treated with histaminase, in comparison with the non-treated rats, whereas no protection was found with the semicarbazide inactivated histaminase. Nitroblue Tetrazolium 78-99 amine oxidase, copper containing 1 Rattus norvegicus 218-229 12951068-3 2003 Computer-assisted morphometry of the ischaemic reperfused hearts stained with nitroblue tetrazolium showed the extension of damaged myocardium (area at risk and infarct size) significantly reduced in rats treated with histaminase, in comparison with the non-treated rats, whereas no protection was found with the semicarbazide inactivated histaminase. Nitroblue Tetrazolium 78-99 amine oxidase, copper containing 1 Rattus norvegicus 339-350 12811016-4 2003 The nitrocellulose sheet was successively incubated with human sera known to contain IgE that binds to rapeseed proteins, alkaline phosphatase-conjugated goat anti-human IgE and 5-bromo-4-chloro-3-indolyl phosphate and nitroblue tetrazolium. Nitroblue Tetrazolium 219-240 immunoglobulin heavy constant epsilon Homo sapiens 85-88 13678532-4 2003 Ang II significantly stimulated superoxide formation in monocytes, as measured by nitro blue tetrazolium reduction assay, as well as the chemotactic response to MCP-1 with the increased expression of CCR2 determined by RT-PCR and western blotting analysis. Nitroblue Tetrazolium 82-104 angiotensinogen Homo sapiens 0-6 14642183-2 2003 METHODS: By using U937 cell line as a model, the induced differentiation of MTX or GM-CSF or their combination was detected by NBT reduction test, morphological observation and CD(14) expression. Nitroblue Tetrazolium 127-130 metaxin 1 Homo sapiens 76-79 14642183-2 2003 METHODS: By using U937 cell line as a model, the induced differentiation of MTX or GM-CSF or their combination was detected by NBT reduction test, morphological observation and CD(14) expression. Nitroblue Tetrazolium 127-130 colony stimulating factor 2 Homo sapiens 83-89 12880368-5 2003 NaF at subtoxic concentrations (<0.5 mM) significantly up-regulated activities of several intracellular enzymes (lactate dehydrogenase, beta-glucuronidase, acid phosphatase), cellular reduction of nitroblue tetrazolium, and nitric oxide (NO) production; which are all accepted as general differentiation markers. Nitroblue Tetrazolium 200-221 C-X-C motif chemokine ligand 8 Homo sapiens 0-3 12677525-3 2003 The ability of HL-60 cells to reduce nitroblue tetrazolium (NBT) was significantly increased after APC treatment for 72 h. In these differentiating HL-60 cells, cell surface differentiation markers CD11b (for myeloid cells) and CD14 (for monocytic cells) were detected in 90.3 % and 70.1 % of the cells, respectively. Nitroblue Tetrazolium 37-58 CD14 molecule Homo sapiens 228-232 12677525-3 2003 The ability of HL-60 cells to reduce nitroblue tetrazolium (NBT) was significantly increased after APC treatment for 72 h. In these differentiating HL-60 cells, cell surface differentiation markers CD11b (for myeloid cells) and CD14 (for monocytic cells) were detected in 90.3 % and 70.1 % of the cells, respectively. Nitroblue Tetrazolium 60-63 integrin subunit alpha M Homo sapiens 198-203 12677525-3 2003 The ability of HL-60 cells to reduce nitroblue tetrazolium (NBT) was significantly increased after APC treatment for 72 h. In these differentiating HL-60 cells, cell surface differentiation markers CD11b (for myeloid cells) and CD14 (for monocytic cells) were detected in 90.3 % and 70.1 % of the cells, respectively. Nitroblue Tetrazolium 60-63 CD14 molecule Homo sapiens 228-232 12045229-12 2002 Finally, coexpression of active Rac1 and active MEK1 induced the motility of NBT-II cells, suggesting that Ras mediates NBT-II cell scattering through the coordinate activation of Rac and the Raf/MAPK pathway. Nitroblue Tetrazolium 77-80 Rac family small GTPase 1 Rattus norvegicus 32-36 12399974-6 2002 SS (400 microg/ml, 6 days) induced 60% and 55% of NBT-positive cells in HL-60 and U937 cell lines, which were augmented in the presence of GM-CSF (25 ng/ml) to levels (85% and 81%, respectively) comparable to those induced by ATRA. Nitroblue Tetrazolium 50-53 colony stimulating factor 2 Homo sapiens 139-145 12324654-7 2002 Retinoic acid also induced a higher percentage of functionally differentiated blr1 transfectants as assessed by nitroblue tetrazolium reduction. Nitroblue Tetrazolium 112-133 C-X-C motif chemokine receptor 5 Homo sapiens 78-82 12389121-5 2002 SOD-like activity was measured as the inhibition of nitroblue tetrazolium reduction due to superoxide anion generation by xanthine plus xanthine oxidase. Nitroblue Tetrazolium 52-73 superoxide dismutase 1 Homo sapiens 0-3 12624657-6 2003 With the addition of THP at 500 nM, there was a significant decrease in the release of LDH and the production of MDA and NBT. Nitroblue Tetrazolium 121-124 uromodulin Canis lupus familiaris 21-24 12225656-3 2002 Superoxide dismutase (SOD)-inhibitable nitroblue tetrazolium (NBT) reduction was determined as an index of O(-)(2) generation. Nitroblue Tetrazolium 39-60 superoxide dismutase 1 Homo sapiens 0-20 12225656-3 2002 Superoxide dismutase (SOD)-inhibitable nitroblue tetrazolium (NBT) reduction was determined as an index of O(-)(2) generation. Nitroblue Tetrazolium 39-60 superoxide dismutase 1 Homo sapiens 22-25 12225656-3 2002 Superoxide dismutase (SOD)-inhibitable nitroblue tetrazolium (NBT) reduction was determined as an index of O(-)(2) generation. Nitroblue Tetrazolium 62-65 superoxide dismutase 1 Homo sapiens 0-20 12225656-3 2002 Superoxide dismutase (SOD)-inhibitable nitroblue tetrazolium (NBT) reduction was determined as an index of O(-)(2) generation. Nitroblue Tetrazolium 62-65 superoxide dismutase 1 Homo sapiens 22-25 12225656-5 2002 FPI increased SOD-inhibitable NBT reduction, but pretreatment with norbinaltorphimine, a dynorphin antagonist, or NS398, a COX-2 inhibitor, blunted such reduction (1 +/- 1 vs. 19 +/- 3 vs. 4 +/- 1 vs. 4 +/- 1 pmol/mm(2) for control, FPI, FPI-norbinaltorphimine and FPI-NS398, respectively). Nitroblue Tetrazolium 30-33 superoxide dismutase 1 Homo sapiens 14-17 12225656-6 2002 Under non-brain injury conditions, dynorphin, in a concentration observed in CSF after FPI, also increased SOD-inhibitable NBT reduction, which was blunted by NS398. Nitroblue Tetrazolium 123-126 superoxide dismutase 1 Homo sapiens 107-110 12045229-12 2002 Finally, coexpression of active Rac1 and active MEK1 induced the motility of NBT-II cells, suggesting that Ras mediates NBT-II cell scattering through the coordinate activation of Rac and the Raf/MAPK pathway. Nitroblue Tetrazolium 77-80 mitogen activated protein kinase kinase 1 Rattus norvegicus 48-52 12045229-12 2002 Finally, coexpression of active Rac1 and active MEK1 induced the motility of NBT-II cells, suggesting that Ras mediates NBT-II cell scattering through the coordinate activation of Rac and the Raf/MAPK pathway. Nitroblue Tetrazolium 120-123 Rac family small GTPase 1 Rattus norvegicus 32-36 12045229-12 2002 Finally, coexpression of active Rac1 and active MEK1 induced the motility of NBT-II cells, suggesting that Ras mediates NBT-II cell scattering through the coordinate activation of Rac and the Raf/MAPK pathway. Nitroblue Tetrazolium 120-123 mitogen activated protein kinase kinase 1 Rattus norvegicus 48-52 12545210-3 2002 From the square-wave voltammetry of native PPO II, peroxide-PPO II complex and azide-PPO II complex, the reduction of nitro blue tetrazolium by the enzymes and activation of PPO II by peroxide it follows that the binding of azide to PPO II induces the formation of CuO(2)(2-)Cu in the active site of PPO II from CuO(2)(-)Cu in native PPO II. Nitroblue Tetrazolium 118-140 protoporphyrinogen oxidase, mitochondrial Nicotiana tabacum 43-49 12545210-3 2002 From the square-wave voltammetry of native PPO II, peroxide-PPO II complex and azide-PPO II complex, the reduction of nitro blue tetrazolium by the enzymes and activation of PPO II by peroxide it follows that the binding of azide to PPO II induces the formation of CuO(2)(2-)Cu in the active site of PPO II from CuO(2)(-)Cu in native PPO II. Nitroblue Tetrazolium 118-140 protoporphyrinogen oxidase, mitochondrial Nicotiana tabacum 60-66 12545210-3 2002 From the square-wave voltammetry of native PPO II, peroxide-PPO II complex and azide-PPO II complex, the reduction of nitro blue tetrazolium by the enzymes and activation of PPO II by peroxide it follows that the binding of azide to PPO II induces the formation of CuO(2)(2-)Cu in the active site of PPO II from CuO(2)(-)Cu in native PPO II. Nitroblue Tetrazolium 118-140 protoporphyrinogen oxidase, mitochondrial Nicotiana tabacum 60-66 12545210-3 2002 From the square-wave voltammetry of native PPO II, peroxide-PPO II complex and azide-PPO II complex, the reduction of nitro blue tetrazolium by the enzymes and activation of PPO II by peroxide it follows that the binding of azide to PPO II induces the formation of CuO(2)(2-)Cu in the active site of PPO II from CuO(2)(-)Cu in native PPO II. Nitroblue Tetrazolium 118-140 protoporphyrinogen oxidase, mitochondrial Nicotiana tabacum 60-66 12545210-3 2002 From the square-wave voltammetry of native PPO II, peroxide-PPO II complex and azide-PPO II complex, the reduction of nitro blue tetrazolium by the enzymes and activation of PPO II by peroxide it follows that the binding of azide to PPO II induces the formation of CuO(2)(2-)Cu in the active site of PPO II from CuO(2)(-)Cu in native PPO II. Nitroblue Tetrazolium 118-140 protoporphyrinogen oxidase, mitochondrial Nicotiana tabacum 60-66 12545210-3 2002 From the square-wave voltammetry of native PPO II, peroxide-PPO II complex and azide-PPO II complex, the reduction of nitro blue tetrazolium by the enzymes and activation of PPO II by peroxide it follows that the binding of azide to PPO II induces the formation of CuO(2)(2-)Cu in the active site of PPO II from CuO(2)(-)Cu in native PPO II. Nitroblue Tetrazolium 118-140 protoporphyrinogen oxidase, mitochondrial Nicotiana tabacum 60-66 12545210-3 2002 From the square-wave voltammetry of native PPO II, peroxide-PPO II complex and azide-PPO II complex, the reduction of nitro blue tetrazolium by the enzymes and activation of PPO II by peroxide it follows that the binding of azide to PPO II induces the formation of CuO(2)(2-)Cu in the active site of PPO II from CuO(2)(-)Cu in native PPO II. Nitroblue Tetrazolium 118-140 protoporphyrinogen oxidase, mitochondrial Nicotiana tabacum 60-66 11750096-5 2001 The effect of introduction of p16(INK4A) on capacity for induced differentiation, assayed by capacity to reduce nitroblue tetrazolium, was determined. Nitroblue Tetrazolium 112-133 cyclin dependent kinase inhibitor 2A Homo sapiens 30-33 11750096-5 2001 The effect of introduction of p16(INK4A) on capacity for induced differentiation, assayed by capacity to reduce nitroblue tetrazolium, was determined. Nitroblue Tetrazolium 112-133 cyclin dependent kinase inhibitor 2A Homo sapiens 34-39 11250656-7 2001 In addition, HOXB4 antisense partially blocked 1,25-(OH)2D(3)-mediated decrease in c-myc levels (46+/-6% inhibition) and promotion of HL-60 cell differentiation (20+/-2% and 25+/-3% inhibition as assessed by nitroblue tetrazolium and non-specific esterase assays respectively). Nitroblue Tetrazolium 208-229 homeobox B4 Homo sapiens 13-18 20954153-3 2001 Activity can be measured as described in this unit by a number of indirect competitive inhibition assays based on the principle that the superoxide anion radical will reduce an inhibitory substrate [such as nitroblue tetrazolium (NBT) or cytochrome c] and SOD activity will reduce the rate of reduction in a competitive fashion. Nitroblue Tetrazolium 230-233 superoxide dismutase 2 Homo sapiens 256-259 11290591-7 2001 After overexpression of PU.1, MEL cells became adherent and phagocytic and showed enhanced nitroblue tetrazolium reduction activity. Nitroblue Tetrazolium 91-112 spleen focus forming virus (SFFV) proviral integration oncogene Mus musculus 24-28 11686491-3 2001 Under non-brain injury conditions, topical ET-1 (10(-10) M, the concentration present in CSF following FPI) increased SOD-inhibitable NBT reduction from 1 +/- 1 to 17 +/- 3 pmol/mm2. Nitroblue Tetrazolium 134-137 endothelin-1 Sus scrofa 43-47 11489250-3 2001 Under non-brain injury conditions, topical vasopressin (40 pg/ml, the concentration present in CSF following FPI) increased SOD inhibitable NBT reduction from 1+/-1 to 25+/-4 pmol/mm(2). Nitroblue Tetrazolium 140-143 vasopressin Sus scrofa 43-54 11500544-3 2001 Addition of PA promoted the synthesis of superoxide in the PLD alpha-depleted plants, as measured by chemiluminescence and superoxide dismutase-inhibitable, NADPH-dependent reduction of cytochrome c and nitroblue tetrazolium. Nitroblue Tetrazolium 203-224 phospholipase D alpha 1 Arabidopsis thaliana 59-62 11387506-8 2001 RESULTS: Under sham injury conditions, topical vasopressin (40 pg/mL, the concentration present in CSF after FPI) increased superoxide dismutase-inhibitable NBT reduction from 1+/-1 to 23+/-4 pmol/mm(2). Nitroblue Tetrazolium 157-160 vasopressin Sus scrofa 47-58 10893205-5 2000 Additionally, neutrophils recovered from the lung lavage fluid of rats given IL-1 intratracheally reduced more nitro blue tetrazolium (NBT) in vitro than neutrophils recovered from control rats or rats that had been given WEB-2086 and then IL-1. Nitroblue Tetrazolium 111-133 interleukin 1 alpha Homo sapiens 77-81 11054668-5 2000 As measured by expressions of differentiation markers and the functional assessment of the ability to reduce nitroblue-tetrazolium, our results further showed that over-expression of nucleophosmin/B23 decreased the response of the cells to RA-induced differentiation. Nitroblue Tetrazolium 109-130 nucleophosmin 1 Homo sapiens 183-196 11054668-5 2000 As measured by expressions of differentiation markers and the functional assessment of the ability to reduce nitroblue-tetrazolium, our results further showed that over-expression of nucleophosmin/B23 decreased the response of the cells to RA-induced differentiation. Nitroblue Tetrazolium 109-130 nucleophosmin 1 Homo sapiens 197-200 11374170-5 2000 About 56% of HL-60 cells exposed to c-myc AS-ODN/lipofectin complex were NBT-positive and showed morphological changes with differentiated phenotype compared with 29% of untreated cells. Nitroblue Tetrazolium 73-76 MYC proto-oncogene, bHLH transcription factor Homo sapiens 36-41 10893205-5 2000 Additionally, neutrophils recovered from the lung lavage fluid of rats given IL-1 intratracheally reduced more nitro blue tetrazolium (NBT) in vitro than neutrophils recovered from control rats or rats that had been given WEB-2086 and then IL-1. Nitroblue Tetrazolium 135-138 interleukin 1 alpha Homo sapiens 77-81 10848831-9 2000 All NADPH oxidase subunits were constitutively present, but nitroblue tetrazolium reduction was only detectable upon activation with IFN-gamma. Nitroblue Tetrazolium 60-81 interferon gamma Homo sapiens 133-142 11108571-5 2000 G-CSF caused the transformants expressing G-CSFR to display a morphological characteristic of mature granulocytes, upregulated CD11b on the cell surface, and improved NBT reduction activity. Nitroblue Tetrazolium 167-170 colony stimulating factor 3 Homo sapiens 0-5 11108571-5 2000 G-CSF caused the transformants expressing G-CSFR to display a morphological characteristic of mature granulocytes, upregulated CD11b on the cell surface, and improved NBT reduction activity. Nitroblue Tetrazolium 167-170 colony stimulating factor 3 receptor Homo sapiens 42-48 10394165-12 1999 In a comparison of patient groups across the CEAP classes, the NBT-positive granulocyte counts were significantly greater in classes 4, 5, and 6 than in classes 2 and 3 (P <.001). Nitroblue Tetrazolium 63-66 biogenesis of lysosomal organelles complex 1 subunit 2 Homo sapiens 45-49 10696106-3 2000 NBT altered the frequency distribution of BK channel open times from a two exponential to a single exponential form. Nitroblue Tetrazolium 0-3 potassium calcium-activated channel subfamily M alpha 1 Rattus norvegicus 42-52 10696106-7 2000 The combined effects of internal NBT on mean open and closed times resulted in the suppression of BK channel open probability when measured at positive membrane potentials. Nitroblue Tetrazolium 33-36 potassium calcium-activated channel subfamily M alpha 1 Rattus norvegicus 98-108 10696106-10 2000 Externally applied NBT suppressed BK channel open probability at concentrations which also inhibit nitric oxide synthase (NOS). Nitroblue Tetrazolium 19-22 potassium calcium-activated channel subfamily M alpha 1 Rattus norvegicus 34-44 10698209-8 2000 In LS, the NBT reaction revealed evidence of superoxide production associated with CD68+HLA-DR+ cells. Nitroblue Tetrazolium 11-14 CD68 molecule Homo sapiens 83-87 10684960-4 1999 When the HL60 cell line expressing the mutant MEF2D was induced to differentiate by VitD(3) treatment, cell surface expression of CD14 and the ability to reduce NBT, which are important characteristics of differentiated monocytes, were significantly decreased compared with control HL60 cells. Nitroblue Tetrazolium 161-164 myocyte enhancer factor 2D Homo sapiens 46-51 9880243-3 1998 The nitroblue tetrazolium (NBT) test of NADPH oxidase activity was used to screen transduced cells for vector-mediated expression of recombinant gp91phox. Nitroblue Tetrazolium 4-25 cytochrome b-245 beta chain Homo sapiens 145-153 11127803-4 1999 Preincubation of intact human neutrophils with INF-alpha and subsequent stimulation with calcium ionophore A23187 also enhanced significantly superoxide radical generation that reduced nitroblue tetrazolium into blue formazan. Nitroblue Tetrazolium 185-206 interferon alpha 17 Homo sapiens 47-56 10339483-2 1999 Exposure of WEHI-3B D+ myelomonocytic leukemia and myeloid LGM-1 cells overexpressing the G-CSFR to G-CSF resulted in induction of differentiation as measured by (1) the ability to reduce nitroblue tetrazolium (NBT), (2) the expression of Mac-I antigen, and (3) the expression of FcgammaII/III receptor. Nitroblue Tetrazolium 188-209 colony stimulating factor 3 receptor Homo sapiens 90-96 10339483-2 1999 Exposure of WEHI-3B D+ myelomonocytic leukemia and myeloid LGM-1 cells overexpressing the G-CSFR to G-CSF resulted in induction of differentiation as measured by (1) the ability to reduce nitroblue tetrazolium (NBT), (2) the expression of Mac-I antigen, and (3) the expression of FcgammaII/III receptor. Nitroblue Tetrazolium 188-209 colony stimulating factor 3 Homo sapiens 90-95 10339483-2 1999 Exposure of WEHI-3B D+ myelomonocytic leukemia and myeloid LGM-1 cells overexpressing the G-CSFR to G-CSF resulted in induction of differentiation as measured by (1) the ability to reduce nitroblue tetrazolium (NBT), (2) the expression of Mac-I antigen, and (3) the expression of FcgammaII/III receptor. Nitroblue Tetrazolium 211-214 colony stimulating factor 3 receptor Homo sapiens 90-96 10339483-2 1999 Exposure of WEHI-3B D+ myelomonocytic leukemia and myeloid LGM-1 cells overexpressing the G-CSFR to G-CSF resulted in induction of differentiation as measured by (1) the ability to reduce nitroblue tetrazolium (NBT), (2) the expression of Mac-I antigen, and (3) the expression of FcgammaII/III receptor. Nitroblue Tetrazolium 211-214 colony stimulating factor 3 Homo sapiens 90-95 10337917-8 1999 Equal to the CL technique, nitroblue tetrazolium (NBT) staining of RAW 264.7 showed SOD-inhibitable formazan precipitation when stimulated with pneumococci. Nitroblue Tetrazolium 27-48 superoxide dismutase 1 Homo sapiens 84-87 10337917-8 1999 Equal to the CL technique, nitroblue tetrazolium (NBT) staining of RAW 264.7 showed SOD-inhibitable formazan precipitation when stimulated with pneumococci. Nitroblue Tetrazolium 50-53 superoxide dismutase 1 Homo sapiens 84-87 9952315-4 1999 RXR agonists alone induced nitroblue tetrazolium (NBT) reduction and expression of CD11b in U937 cells, whereas RAR agonists alone did not. Nitroblue Tetrazolium 27-48 retinoid X receptor alpha Homo sapiens 0-3 9952315-4 1999 RXR agonists alone induced nitroblue tetrazolium (NBT) reduction and expression of CD11b in U937 cells, whereas RAR agonists alone did not. Nitroblue Tetrazolium 50-53 retinoid X receptor alpha Homo sapiens 0-3 9880243-3 1998 The nitroblue tetrazolium (NBT) test of NADPH oxidase activity was used to screen transduced cells for vector-mediated expression of recombinant gp91phox. Nitroblue Tetrazolium 27-30 cytochrome b-245 beta chain Homo sapiens 145-153 9588900-4 1998 To this purpose, rats were treated with carbon tetrachloride (CCl4) and livers subjected to in situ perfusion with nitroblue tetrazolium, which, in the presence of superoxide ions, is reduced to an insoluble blue-colored formazan derivative and is readily detectable in the tissue by light microscopy. Nitroblue Tetrazolium 115-136 C-C motif chemokine ligand 4 Rattus norvegicus 62-66 18425640-2 1998 After incubation with 200 U/mL IL-12 for 48 h, DNA synthesis of FBL-3 cells in S phase decreased significantly; the expression of CD14 which is the specific marker of monocyte increased, the rate of NBT(+) cells was apparently higher than that of the untreated FBL-3 cells. Nitroblue Tetrazolium 199-202 F-box and leucine rich repeat protein 3 Homo sapiens 64-69 18425640-2 1998 After incubation with 200 U/mL IL-12 for 48 h, DNA synthesis of FBL-3 cells in S phase decreased significantly; the expression of CD14 which is the specific marker of monocyte increased, the rate of NBT(+) cells was apparently higher than that of the untreated FBL-3 cells. Nitroblue Tetrazolium 199-202 CD14 molecule Homo sapiens 130-134 18425640-2 1998 After incubation with 200 U/mL IL-12 for 48 h, DNA synthesis of FBL-3 cells in S phase decreased significantly; the expression of CD14 which is the specific marker of monocyte increased, the rate of NBT(+) cells was apparently higher than that of the untreated FBL-3 cells. Nitroblue Tetrazolium 199-202 F-box and leucine rich repeat protein 3 Homo sapiens 261-266 9767552-1 1998 BACKGROUND: Nitroblue tetrazolium (NBT) reduction to formazan has been used as a marker for nitric oxide synthase (NOS). Nitroblue Tetrazolium 12-33 nitric oxide synthase 2 Homo sapiens 92-113 9767552-1 1998 BACKGROUND: Nitroblue tetrazolium (NBT) reduction to formazan has been used as a marker for nitric oxide synthase (NOS). Nitroblue Tetrazolium 35-38 nitric oxide synthase 2 Homo sapiens 92-113 9767552-9 1998 Superoxide dismutase/catalase decreased NBT reduction. Nitroblue Tetrazolium 40-43 catalase Homo sapiens 21-29 9617758-4 1998 SIN-1 reduced nitro blue tetrazolium and the effect was inhibitable by superoxide dismutase. Nitroblue Tetrazolium 14-36 MAPK associated protein 1 Homo sapiens 0-5 9572303-7 1998 Sensitivity of the nitroblue tetrazolium reduction to superoxide dismutase indicated that the reduction of LY 83583 by NAD(P)H:quinone oxidoreductase leads to superoxide generation. Nitroblue Tetrazolium 19-40 crystallin zeta Homo sapiens 127-149 9605667-6 1998 Quantification for eIF4E protein level was accomplished using a rabbit anti-eIF4E antibody and colorimetric development of Western blots using nitro blue tetrazolium and 5-bromo-4-chloro-3-indolyl phosphate. Nitroblue Tetrazolium 143-165 eukaryotic translation initiation factor 4E Homo sapiens 19-24 9617758-5 1998 Reduction of nitro blue tetrazolium was not detected in the solutions of GEA 3162 and S-nitroso-N-acetylpenicillamine suggesting that SIN-1 but not GEA 3162 and S-nitroso-N-acetylpenicillamine release O2.- in their decomposition process. Nitroblue Tetrazolium 13-35 MAPK associated protein 1 Homo sapiens 134-139 9327726-8 1997 The CYP2A5 immunohistochemical staining co-localized with formazan deposits resulting from nitro blue tetrazolium reduction and occurred in nuclei as well as cytoplasm. Nitroblue Tetrazolium 91-113 cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus 4-10 9459619-8 1997 In the rIFN-gamma group, toxicity was mild and some biological changes were seen (NK/LAK activation, increase of phagocytosis and of NBT reduction). Nitroblue Tetrazolium 133-136 interferon gamma Rattus norvegicus 7-17 9579370-8 1998 The known tumor suppressor genes retinoblastoma (RB) and p53 showed loss of expression in GMTT compared with NBT. Nitroblue Tetrazolium 109-112 RB transcriptional corepressor 1 Homo sapiens 33-47 9579370-8 1998 The known tumor suppressor genes retinoblastoma (RB) and p53 showed loss of expression in GMTT compared with NBT. Nitroblue Tetrazolium 109-112 RB transcriptional corepressor 1 Homo sapiens 49-51 9579370-8 1998 The known tumor suppressor genes retinoblastoma (RB) and p53 showed loss of expression in GMTT compared with NBT. Nitroblue Tetrazolium 109-112 tumor protein p53 Homo sapiens 57-60 9493559-9 1998 Nitroblue tetrazolium-reducing mononuclear cells were CD68 or RFD7 positive but they were rarely positive for HLA-DR and RFD1. Nitroblue Tetrazolium 0-21 CD68 molecule Homo sapiens 54-58 9395219-7 1997 Perfusion of liver with nitroblue tetrazolium, an indicator for superoxide formation, demonstrated that in livers of infected mice, hepatocytes often co-expressed CYP2A5 and formazan deposition. Nitroblue Tetrazolium 24-45 cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus 163-169 27406670-1 1996 Using various superoxide generating systems and nitroblue tetrazolium or cytochrome c as superoxide detector molecules it is possible to assess the superoxide dismutase activity of proteins. Nitroblue Tetrazolium 48-69 superoxide dismutase 1 Homo sapiens 148-168 9216650-2 1997 ATRA alone caused only slight induction of NBT-reducing activity even at a high concentration (10(-7) M), but when combined with GM-CSF, it led to remarkable increase in the induction of NBT-reducing activity. Nitroblue Tetrazolium 187-190 colony stimulating factor 2 Homo sapiens 129-135 8978280-11 1997 Long-term exposure (5 days) of HL-60 cells to IFN-gamma caused an increase in nitroblue tetrazolium (NBT)-reducing and nonspecific esterase (NSE) activity and induced expression of Fc gamma RI (CD64) without significant effects on cell number, adherence, or phagocytic activity. Nitroblue Tetrazolium 101-104 interferon gamma Homo sapiens 46-55 9073351-3 1997 This is followed by specific counterstaining of glutathione reductase with dichlorophenolindophenol/nitroblue tetrazolium. Nitroblue Tetrazolium 100-121 glutathione-disulfide reductase Homo sapiens 48-69 9112257-1 1997 Treatment of human promyelocytic leukemia HL-60 cells with 10 muM curcumin for 48 h inhibited cellular proliferation and induced small increases in differentiation (100-200%) as measured by the proportion of cells that reduced nitroblue tetrazolium (NBT) and expressed Mac-1. Nitroblue Tetrazolium 227-248 latexin Homo sapiens 62-65 9112257-1 1997 Treatment of human promyelocytic leukemia HL-60 cells with 10 muM curcumin for 48 h inhibited cellular proliferation and induced small increases in differentiation (100-200%) as measured by the proportion of cells that reduced nitroblue tetrazolium (NBT) and expressed Mac-1. Nitroblue Tetrazolium 250-253 latexin Homo sapiens 62-65 8996511-10 1997 Topical ET-1 (10(-10) mol/L) increased SOD-inhibitable NBT reduction from 1 +/- 1 to 16 +/- 3 pmol/mm2, similar to previously reported NBT reduction after FPI (14 +/- 2 pmol/mm2). Nitroblue Tetrazolium 55-58 endothelin-1 Sus scrofa 8-12 8996511-11 1997 BQ123 (10(-6) mol/L), an ET-1 antagonist, blunted the NBT reduction observed after FPI (4 +/- 1 pmol/mm2). Nitroblue Tetrazolium 54-57 endothelin-1 Sus scrofa 25-29 8915775-3 1996 NaF increased cellular reduction of nitroblue tetrazolium (NBT), and this effect was strongly augmented by 1,25(OH)2D3. Nitroblue Tetrazolium 36-57 C-X-C motif chemokine ligand 8 Homo sapiens 0-3 8915775-3 1996 NaF increased cellular reduction of nitroblue tetrazolium (NBT), and this effect was strongly augmented by 1,25(OH)2D3. Nitroblue Tetrazolium 59-62 C-X-C motif chemokine ligand 8 Homo sapiens 0-3 8915775-10 1996 Indomethacin completely blocked stimulation of NBT reduction, NO production, and iNOS expression induced by NaF plus 1,25(OH)2D3; adding exogenous PGE2 (0.1-10 ng/ml) to these indomethacin-blocked cultures dose-dependently restored NO production. Nitroblue Tetrazolium 47-50 C-X-C motif chemokine ligand 8 Homo sapiens 108-111 8839832-13 1996 Overexpression of the CD30v induced differentiation of HL-60 cells as evidenced by an increased NBT reduction activity. Nitroblue Tetrazolium 96-99 TNF receptor superfamily member 8 Homo sapiens 22-26 8743726-5 1996 Thus, nitrotetrazolium blue strongly inhibited the activity of plasmin, urokinase (fibrinolytic activity), papain and pepsin. Nitroblue Tetrazolium 6-27 plasminogen Homo sapiens 63-70 8806808-2 1996 Reduction of nitroblue tetrazolium by stimulated tonsillar B cells is inhibited by superoxide dismutase (SOD). Nitroblue Tetrazolium 13-34 superoxide dismutase 1 Homo sapiens 83-103 8806808-2 1996 Reduction of nitroblue tetrazolium by stimulated tonsillar B cells is inhibited by superoxide dismutase (SOD). Nitroblue Tetrazolium 13-34 superoxide dismutase 1 Homo sapiens 105-108 8635162-3 1996 SOD was assayed using a modification of the indirect nitroblue tetrazolium assay method, while CAT was measured by a spectrophotometric method. Nitroblue Tetrazolium 53-74 superoxide dismutase 1 Homo sapiens 0-3 8853896-5 1996 More importantly, C-JUN AS oligonucleotides showed distinct effects on two markers of PMA-induced differentiation; the C-JUN AS oligonucleotides inhibited cell adhesion, whereas they did not affect another marker of differentiation, respiratory burst (measured by nitro blue tetrazolium reduction assay). Nitroblue Tetrazolium 264-286 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 18-23 8590308-0 1995 Inhibition of vitamin D3-induced cell differentiation by interferon-gamma in HL-60 cells determined by a nitroblue tetrazolium reduction test. Nitroblue Tetrazolium 105-126 interferon gamma Homo sapiens 57-73 8740254-2 1996 METHODS: Nitro blue tetrazolium (NBT) staining, a marker of reductants which may be induced by free radicals such as superoxide, and catalase activity, as an indirect measure of hydrogen peroxide (H2O2) generation, were studied in the rat retina in three conditions known to cause diabetes-like retinopathy, i.e. rats with spontaneous diabetes (the BB Wistar rat), rats with streptozotocin-induced diabetes mellitus, and rats fed on galactose. Nitroblue Tetrazolium 33-36 catalase Rattus norvegicus 133-141 8611027-4 1996 Spectroscopic studies indicated NADH:molecular oxygen reductase activity resulted in the production of the superoxide radical, detected as the formation of adrenochrome from epinephrine and by the formation of adrenochrome from epinephrine and by the reduction of nitroblue tetrazolium, both of which could be inhibited by the addition of superoxide dismutase and were unaffected by the addition of catalase. Nitroblue Tetrazolium 264-285 catalase Homo sapiens 399-407 8852433-3 1996 Here, the distribution of dihydroorotate dehydrogenase activity in cryostat sections of various rat tissues, and tissue samples of human skin and kidney, was visualized by light microscopy using the nitroblue tetrazolium technique. Nitroblue Tetrazolium 199-220 dihydroorotate dehydrogenase Mus musculus 26-54 8852433-7 1996 Dihydroorotate dehydrogenase and succinate dehydrogenase activity in Ehrlich ascites tumor cells grown in suspension culture were quantified by application of nitroblue tetrazolium or cyanotolyl tetrazolium and subsequent extraction of the insoluble formazans with organic solvents. Nitroblue Tetrazolium 159-180 dihydroorotate dehydrogenase Mus musculus 0-28 8532118-8 1995 The qualitative localization of the enzyme activity on non SDS-PAGE by nitroblue tetrazolium staining confirmed the increase of MAO-B during the development. Nitroblue Tetrazolium 71-92 monoamine oxidase B Rattus norvegicus 128-133 7549963-0 1995 Spectrophotometric assay for superoxide dismutase based on the nitroblue tetrazolium reduction by glucose-glucose oxidase. Nitroblue Tetrazolium 63-84 superoxide dismutase 1 Homo sapiens 29-49 8578193-8 1995 Nitroblue tetrazolium reducing vessels were increased in inflamed mucosa, and these vessels expressed ICAM-1 and CD31. Nitroblue Tetrazolium 0-21 intercellular adhesion molecule 1 Homo sapiens 102-108 8578193-8 1995 Nitroblue tetrazolium reducing vessels were increased in inflamed mucosa, and these vessels expressed ICAM-1 and CD31. Nitroblue Tetrazolium 0-21 platelet and endothelial cell adhesion molecule 1 Homo sapiens 113-117 8578193-9 1995 E-selectin positivity in association with nitroblue tetrazolium reduction was mainly seen in the large mucosal vessels, but capillaries showing nitroblue tetrazolium reduction were rarely positive for E-selectin. Nitroblue Tetrazolium 42-63 selectin E Homo sapiens 0-10 8569737-6 1995 And finally, the data is presented that acetylcholine-induced elevations of intracellular levels of cyclic GMP can be attenuated by muscarinic antagonist, atropine and superoxide anion scavenger, nitroblue tetrazolium. Nitroblue Tetrazolium 196-217 5'-nucleotidase, cytosolic II Homo sapiens 107-110 7621441-3 1995 Induction of differentiation observed are in the order SBP > SBA > SBF, as assessed by morphology, NBT-reducing activity and surface marker antigens of the treated cells. Nitroblue Tetrazolium 105-108 selenium binding protein 1 Homo sapiens 55-58 7549963-2 1995 The assay is based on the SOD-mediated inhibition in the rate of nitroblue tetrazolium reduction to the blue formazan at alkaline pH. Nitroblue Tetrazolium 65-86 superoxide dismutase 1 Homo sapiens 26-29 7805791-3 1994 Hybrid chains formed by probe and calcitonin mRNA were visualized by anti-digoxigenin-alkaline phosphatase conjugate, nitroblue tetrazolium (NBT) and X-phosphate (Boehringer Mannheim). Nitroblue Tetrazolium 118-139 calcitonin-related polypeptide alpha Rattus norvegicus 34-44 7890662-4 1995 The initial decline in FPGS activity preceded any effect of Me2SO on rate of growth and the increase in appearance of nitro blue tetrazolium-positive cells, a marker of cellular maturation, and the decrease after 5 days of exposure to Me2SO was solely accounted for by a 7-fold decrease in value for Vmax. Nitroblue Tetrazolium 118-140 folylpolyglutamate synthase Homo sapiens 23-27 7528568-5 1995 The cells expressing a high level of D-factor receptor were induced to differentiate by D-factor; about 60% of the cells exhibited the ability to reduce nitroblue tetrazolium and expression of the differentiation antigen Mac-1 (CD11b) on the cell surface increased. Nitroblue Tetrazolium 153-174 leukemia inhibitory factor Mus musculus 37-45 7591362-4 1995 GM-CSF and M-CSF demonstrated equipotency in the induction of monocyte phagocytosis of heat-killed baker"s yeast and in the regulation of the hexose-monophosphate shunt (NBT reduction). Nitroblue Tetrazolium 170-173 colony stimulating factor 2 Homo sapiens 0-6 7591362-4 1995 GM-CSF and M-CSF demonstrated equipotency in the induction of monocyte phagocytosis of heat-killed baker"s yeast and in the regulation of the hexose-monophosphate shunt (NBT reduction). Nitroblue Tetrazolium 170-173 colony stimulating factor 1 Homo sapiens 1-6 8987500-2 1995 STL-1 markedly increased differention-associated characteristics in macrophage, such as nitroblue tetrazolium reducing ability, appearance of Fc receptor, phagocytic activities in U937. Nitroblue Tetrazolium 88-109 collagen type II alpha 1 chain Homo sapiens 0-5 7751736-7 1995 Furthermore, hM-CSF enhanced the activity of RES organ, phagocytosis by macrophages and NBT reduction by macrophages, significantly. Nitroblue Tetrazolium 88-91 colony stimulating factor 1 Homo sapiens 13-19 8050170-2 1994 In the present study we examined the ability to generate reactive oxygen species (ROS) in isolated monocytes from these patients by two different methods: superoxide dismutase (SOD) inhibitable cytochrome c reduction by O2- and nitroblue tetrazolium (NBT) reduction. Nitroblue Tetrazolium 251-254 superoxide dismutase 1 Homo sapiens 155-175 7806621-12 1994 Within the same period, relatively small number of TNF-alpha treated THP-1 cells had differentiated to macrophages as detected by the reduction of nitro blue tetrazolium (NBT) (35% of total cells) and by the counting of adherent cells (35% of total cells). Nitroblue Tetrazolium 147-169 tumor necrosis factor Homo sapiens 51-60 7806621-12 1994 Within the same period, relatively small number of TNF-alpha treated THP-1 cells had differentiated to macrophages as detected by the reduction of nitro blue tetrazolium (NBT) (35% of total cells) and by the counting of adherent cells (35% of total cells). Nitroblue Tetrazolium 147-169 GLI family zinc finger 2 Homo sapiens 69-74 7806621-12 1994 Within the same period, relatively small number of TNF-alpha treated THP-1 cells had differentiated to macrophages as detected by the reduction of nitro blue tetrazolium (NBT) (35% of total cells) and by the counting of adherent cells (35% of total cells). Nitroblue Tetrazolium 171-174 tumor necrosis factor Homo sapiens 51-60 7806621-12 1994 Within the same period, relatively small number of TNF-alpha treated THP-1 cells had differentiated to macrophages as detected by the reduction of nitro blue tetrazolium (NBT) (35% of total cells) and by the counting of adherent cells (35% of total cells). Nitroblue Tetrazolium 171-174 GLI family zinc finger 2 Homo sapiens 69-74 8057087-3 1994 The detection of the rate constant of the reaction of superoxide ion with nitroblue tetrazolium (NBT) which is inhibited by superoxide dismutase (SOD) and its model compounds of the EGTB system has been performed by a modified illumination method. Nitroblue Tetrazolium 74-95 superoxide dismutase 1 Homo sapiens 124-144 8057087-3 1994 The detection of the rate constant of the reaction of superoxide ion with nitroblue tetrazolium (NBT) which is inhibited by superoxide dismutase (SOD) and its model compounds of the EGTB system has been performed by a modified illumination method. Nitroblue Tetrazolium 74-95 superoxide dismutase 1 Homo sapiens 146-149 8057087-3 1994 The detection of the rate constant of the reaction of superoxide ion with nitroblue tetrazolium (NBT) which is inhibited by superoxide dismutase (SOD) and its model compounds of the EGTB system has been performed by a modified illumination method. Nitroblue Tetrazolium 97-100 superoxide dismutase 1 Homo sapiens 124-144 8057087-3 1994 The detection of the rate constant of the reaction of superoxide ion with nitroblue tetrazolium (NBT) which is inhibited by superoxide dismutase (SOD) and its model compounds of the EGTB system has been performed by a modified illumination method. Nitroblue Tetrazolium 97-100 superoxide dismutase 1 Homo sapiens 146-149 8050170-2 1994 In the present study we examined the ability to generate reactive oxygen species (ROS) in isolated monocytes from these patients by two different methods: superoxide dismutase (SOD) inhibitable cytochrome c reduction by O2- and nitroblue tetrazolium (NBT) reduction. Nitroblue Tetrazolium 251-254 superoxide dismutase 1 Homo sapiens 177-180 7520101-5 1994 Interestingly, G-CSF or GM-CSF potentiated the capability of ATRA-induced cells to reduce nitroblue tetrazolium (NBT), while G-CSF or GM-CSF alone induced no NBT reduction. Nitroblue Tetrazolium 90-111 colony stimulating factor 3 Homo sapiens 15-20 7526942-7 1994 The co-purification and the competitive inhibition of NOS by the NADPHd substrate, nitro blue tetrazolium (NBT), are proof that in insects the enzyme responsible for fixation-insensitive NADPHd activity is nitric oxide synthase. Nitroblue Tetrazolium 83-105 Nitric oxide synthase Drosophila melanogaster 206-227 7526942-7 1994 The co-purification and the competitive inhibition of NOS by the NADPHd substrate, nitro blue tetrazolium (NBT), are proof that in insects the enzyme responsible for fixation-insensitive NADPHd activity is nitric oxide synthase. Nitroblue Tetrazolium 107-110 Nitric oxide synthase Drosophila melanogaster 206-227 7520101-5 1994 Interestingly, G-CSF or GM-CSF potentiated the capability of ATRA-induced cells to reduce nitroblue tetrazolium (NBT), while G-CSF or GM-CSF alone induced no NBT reduction. Nitroblue Tetrazolium 90-111 colony stimulating factor 2 Homo sapiens 24-30 7520101-5 1994 Interestingly, G-CSF or GM-CSF potentiated the capability of ATRA-induced cells to reduce nitroblue tetrazolium (NBT), while G-CSF or GM-CSF alone induced no NBT reduction. Nitroblue Tetrazolium 113-116 colony stimulating factor 3 Homo sapiens 15-20 7520101-5 1994 Interestingly, G-CSF or GM-CSF potentiated the capability of ATRA-induced cells to reduce nitroblue tetrazolium (NBT), while G-CSF or GM-CSF alone induced no NBT reduction. Nitroblue Tetrazolium 113-116 colony stimulating factor 2 Homo sapiens 24-30 7954742-6 1994 The activity of platelet SOD was determined by measuring reductivity of nitroblue tetrazolium. Nitroblue Tetrazolium 72-93 superoxide dismutase 1 Homo sapiens 25-28 7947389-5 1994 When these clones were examined immediately after their establishment, expression of c-jun was accompanied by the appearance of a mature phenotype in many clones, as measured by the reduction of nitroblue tetrazolium and by the expression of Mac-1 (CD11b), a cell surface marker on differentiated cells. Nitroblue Tetrazolium 195-216 Jun proto-oncogene, AP-1 transcription factor subunit Homo sapiens 85-90 8182064-11 1994 TNF induced NBT-reducing activity in a dose-dependent manner, whereas LT was essentially inactive. Nitroblue Tetrazolium 12-15 tumor necrosis factor Homo sapiens 0-3 8182064-13 1994 By using receptor-blocking antibodies we found that both p60 and p80 forms of TNF receptors were functional for NBT-reducing activity, but TNF-dependent NF-kappa B activation required only the p60 receptor. Nitroblue Tetrazolium 112-115 interferon induced protein with tetratricopeptide repeats 3 Homo sapiens 57-60 8182064-13 1994 By using receptor-blocking antibodies we found that both p60 and p80 forms of TNF receptors were functional for NBT-reducing activity, but TNF-dependent NF-kappa B activation required only the p60 receptor. Nitroblue Tetrazolium 112-115 coilin Homo sapiens 65-68 8182064-13 1994 By using receptor-blocking antibodies we found that both p60 and p80 forms of TNF receptors were functional for NBT-reducing activity, but TNF-dependent NF-kappa B activation required only the p60 receptor. Nitroblue Tetrazolium 112-115 tumor necrosis factor Homo sapiens 78-81 8161788-5 1994 Morphological analysis, flow-cytometric determination of granulocytic or monocytic surface markers, and ability to reduce nitroblue tetrazolium (NBT) demonstrated that expression of exogenous wild-type p53 gene in HL-60 cells induces differentiation through the granulocytic pathway. Nitroblue Tetrazolium 122-143 tumor protein p53 Homo sapiens 202-205 8161788-5 1994 Morphological analysis, flow-cytometric determination of granulocytic or monocytic surface markers, and ability to reduce nitroblue tetrazolium (NBT) demonstrated that expression of exogenous wild-type p53 gene in HL-60 cells induces differentiation through the granulocytic pathway. Nitroblue Tetrazolium 145-148 tumor protein p53 Homo sapiens 202-205 8141790-1 1994 The effect of tumour necrosis factor alpha (TNF alpha) on superoxide generation in human neutrophils was investigated using the Nitro Blue Tetrazolium reduction assay. Nitroblue Tetrazolium 128-150 tumor necrosis factor Homo sapiens 44-53 7689128-1 1993 Recombinant human granulocyte colony-stimulating factor (rhG-CSF) not only enhanced the growth of HL-60 cells, but also significantly increased NBT-reducing ability and alkaline phosphatase (ALP) activity of the cells, which were enhanced by the treatment with retinoic acid (RA). Nitroblue Tetrazolium 144-147 colony stimulating factor 3 Homo sapiens 18-55 7931813-6 1994 The mean values of fructosamine measured by the NBT reaction in the glycosylated-laminin and fibronectin were increased dose dependently. Nitroblue Tetrazolium 48-51 fibronectin 1 Rattus norvegicus 93-104 8250238-5 1993 Gb3 was visualized with NBT and BCIP and quantitated by densitometry. Nitroblue Tetrazolium 24-27 alpha 1,4-galactosyltransferase (P blood group) Homo sapiens 0-3 8132222-4 1994 However, combinations of IL-4 and TNF-alpha acted in synergy to inhibit cell proliferation and induce monocytic differentiation of JCS cells, as shown by increased expression of the macrophage differentiation antigens (F4/80, Mac-1), stimulation of phagocytic activity, induction of non-specific esterase and NBT-reducing activities, increased plastic adherence and morphological criteria. Nitroblue Tetrazolium 309-312 interleukin 4 Mus musculus 25-29 8132222-4 1994 However, combinations of IL-4 and TNF-alpha acted in synergy to inhibit cell proliferation and induce monocytic differentiation of JCS cells, as shown by increased expression of the macrophage differentiation antigens (F4/80, Mac-1), stimulation of phagocytic activity, induction of non-specific esterase and NBT-reducing activities, increased plastic adherence and morphological criteria. Nitroblue Tetrazolium 309-312 tumor necrosis factor Mus musculus 34-43 8262554-1 1993 Involvement of protein kinase C. The peptides neuropeptide Y (NPY) and peptide YY (PYY) at concentrations from 10(-12) M to 10(-8) M have been shown in this study to stimulate significantly, in vitro, several functions of resting peritoneal macrophages from BALB/c mice: adherence to substrate, chemotaxis, ingestion of inert particles (latex beads) and foreign cells (Candida albicans), and production of superoxide anion measured by nitroblue tetrazolium reduction. Nitroblue Tetrazolium 435-456 neuropeptide Y Mus musculus 46-60 8262554-1 1993 Involvement of protein kinase C. The peptides neuropeptide Y (NPY) and peptide YY (PYY) at concentrations from 10(-12) M to 10(-8) M have been shown in this study to stimulate significantly, in vitro, several functions of resting peritoneal macrophages from BALB/c mice: adherence to substrate, chemotaxis, ingestion of inert particles (latex beads) and foreign cells (Candida albicans), and production of superoxide anion measured by nitroblue tetrazolium reduction. Nitroblue Tetrazolium 435-456 neuropeptide Y Mus musculus 62-65 8262554-1 1993 Involvement of protein kinase C. The peptides neuropeptide Y (NPY) and peptide YY (PYY) at concentrations from 10(-12) M to 10(-8) M have been shown in this study to stimulate significantly, in vitro, several functions of resting peritoneal macrophages from BALB/c mice: adherence to substrate, chemotaxis, ingestion of inert particles (latex beads) and foreign cells (Candida albicans), and production of superoxide anion measured by nitroblue tetrazolium reduction. Nitroblue Tetrazolium 435-456 peptide YY Mus musculus 71-81 8262554-1 1993 Involvement of protein kinase C. The peptides neuropeptide Y (NPY) and peptide YY (PYY) at concentrations from 10(-12) M to 10(-8) M have been shown in this study to stimulate significantly, in vitro, several functions of resting peritoneal macrophages from BALB/c mice: adherence to substrate, chemotaxis, ingestion of inert particles (latex beads) and foreign cells (Candida albicans), and production of superoxide anion measured by nitroblue tetrazolium reduction. Nitroblue Tetrazolium 435-456 peptide YY Mus musculus 83-86 8394678-3 1993 Utr-1, which recognizes the 75 kDa receptor, blocked 125I-TNF binding by about 80% and inhibited by about 80% the TNF-induced NBT reducing activity. Nitroblue Tetrazolium 126-129 tumor necrosis factor Homo sapiens 114-117 8394678-4 1993 Htr-5 recognizes the 55 kDa receptor, blocked 125I-TNF binding by about 20% and inhibited by about 60% the TNF-induced NBT reducing activity. Nitroblue Tetrazolium 119-122 tumor necrosis factor Homo sapiens 107-110 8489236-6 1993 NADH was not an effective electron donor for cytochrome c reduction and NADPH-dependent reduction of nitroblue tetrazolium was negligibly small. Nitroblue Tetrazolium 101-122 2,4-dienoyl-CoA reductase 1 Homo sapiens 72-77 8236374-6 1993 In marked contrast, in SOC, addition of IL-7 resulted in the growth of gamma delta T-cells not only in FT but also in NBT, despite the fact that the SOC of NBT without exogenous cytokine exclusively promoted the growth of alpha beta T-cells. Nitroblue Tetrazolium 118-121 interleukin 7 Mus musculus 40-44 8236374-6 1993 In marked contrast, in SOC, addition of IL-7 resulted in the growth of gamma delta T-cells not only in FT but also in NBT, despite the fact that the SOC of NBT without exogenous cytokine exclusively promoted the growth of alpha beta T-cells. Nitroblue Tetrazolium 156-159 interleukin 7 Mus musculus 40-44 8471626-3 1993 Nitroblue tetrazolium (NBT)-reducing activity, a typical marker of myelomonocytic differentiation, of U937 cells was induced by genistein and GM-CSF enhanced this activity. Nitroblue Tetrazolium 0-21 colony stimulating factor 2 Homo sapiens 142-148 8471626-3 1993 Nitroblue tetrazolium (NBT)-reducing activity, a typical marker of myelomonocytic differentiation, of U937 cells was induced by genistein and GM-CSF enhanced this activity. Nitroblue Tetrazolium 23-26 colony stimulating factor 2 Homo sapiens 142-148 8471626-4 1993 GM-CSF also induced the NBT-reducing activity of the cells in combination with 2,5-dihydroxycinnamic acid methyl ester, psi-tectorigenin and staurosporine, although each of them did not induce the activity. Nitroblue Tetrazolium 24-27 colony stimulating factor 2 Homo sapiens 0-6 7680656-3 1993 A high level of expression of the G-CSFR did not promote or suppress cellular proliferation or initiate differentiation; however, exposure of transfected cells to G-CSF in suspension culture caused a large percentage of the population to enter a differentiation pathway, as determined by two markers of the mature state, the ability of cells to reduce nitroblue tetrazolium (NBT) and to express the differentiation antigen Mac-1 (CD11b) on the cell surface. Nitroblue Tetrazolium 352-373 colony stimulating factor 3 receptor Homo sapiens 34-40 7680656-3 1993 A high level of expression of the G-CSFR did not promote or suppress cellular proliferation or initiate differentiation; however, exposure of transfected cells to G-CSF in suspension culture caused a large percentage of the population to enter a differentiation pathway, as determined by two markers of the mature state, the ability of cells to reduce nitroblue tetrazolium (NBT) and to express the differentiation antigen Mac-1 (CD11b) on the cell surface. Nitroblue Tetrazolium 352-373 colony stimulating factor 3 Homo sapiens 34-39 7680656-3 1993 A high level of expression of the G-CSFR did not promote or suppress cellular proliferation or initiate differentiation; however, exposure of transfected cells to G-CSF in suspension culture caused a large percentage of the population to enter a differentiation pathway, as determined by two markers of the mature state, the ability of cells to reduce nitroblue tetrazolium (NBT) and to express the differentiation antigen Mac-1 (CD11b) on the cell surface. Nitroblue Tetrazolium 375-378 colony stimulating factor 3 receptor Homo sapiens 34-40 7680656-3 1993 A high level of expression of the G-CSFR did not promote or suppress cellular proliferation or initiate differentiation; however, exposure of transfected cells to G-CSF in suspension culture caused a large percentage of the population to enter a differentiation pathway, as determined by two markers of the mature state, the ability of cells to reduce nitroblue tetrazolium (NBT) and to express the differentiation antigen Mac-1 (CD11b) on the cell surface. Nitroblue Tetrazolium 375-378 colony stimulating factor 3 Homo sapiens 34-39 7680656-4 1993 Thus, upon treatment with 10 ng/ml of G-CSF, 60% or more of transfected cells exhibited NBT positivity; whereas, in contrast, nontransfected cells exhibited only 6% NBT positivity in response to G-CSF. Nitroblue Tetrazolium 88-91 colony stimulating factor 3 (granulocyte) Mus musculus 38-43 7680656-4 1993 Thus, upon treatment with 10 ng/ml of G-CSF, 60% or more of transfected cells exhibited NBT positivity; whereas, in contrast, nontransfected cells exhibited only 6% NBT positivity in response to G-CSF. Nitroblue Tetrazolium 165-168 colony stimulating factor 3 (granulocyte) Mus musculus 38-43 18475503-1 1993 Phorbol-12-myristate-13-acetate (PMA), calcium ionophore A23187 and platelet activating factor (PAF) stimulated the generation of oxygen free radicals (nitro-blue tetrazolium reduction) in Ehrlich ascites tumour (EAT) cells. Nitroblue Tetrazolium 152-174 patchy fur Mus musculus 96-99 25990524-6 1993 In 12 cases of clinically diagnosed infarction, H-FABP depletion could be demonstrated in areas that showed normal NBT staining. Nitroblue Tetrazolium 115-118 fatty acid binding protein 3 Homo sapiens 48-54 8380808-1 1993 The neuropeptides neurotensin and neuromedin N (from 10(-12) M to 10(-9) M) have been shown in this study to stimulate significantly in vitro several steps of the phagocytic process: adherence to substrate, chemotaxis, ingestion of inert particles (latex beads) and production of superoxide anion measured by nitroblue tetrazolium reduction in resting peritoneal macrophages from BALB/c mice. Nitroblue Tetrazolium 309-330 neurotensin Mus musculus 18-29 8380808-1 1993 The neuropeptides neurotensin and neuromedin N (from 10(-12) M to 10(-9) M) have been shown in this study to stimulate significantly in vitro several steps of the phagocytic process: adherence to substrate, chemotaxis, ingestion of inert particles (latex beads) and production of superoxide anion measured by nitroblue tetrazolium reduction in resting peritoneal macrophages from BALB/c mice. Nitroblue Tetrazolium 309-330 neurotensin Mus musculus 34-46 8453769-0 1993 A methodological approach to superoxide dismutase (SOD) activity assay based on inhibition of nitroblue tetrazolium (NBT) reduction. Nitroblue Tetrazolium 94-115 superoxide dismutase 1 Homo sapiens 29-49 8453769-0 1993 A methodological approach to superoxide dismutase (SOD) activity assay based on inhibition of nitroblue tetrazolium (NBT) reduction. Nitroblue Tetrazolium 94-115 superoxide dismutase 1 Homo sapiens 51-54 8453769-0 1993 A methodological approach to superoxide dismutase (SOD) activity assay based on inhibition of nitroblue tetrazolium (NBT) reduction. Nitroblue Tetrazolium 117-120 superoxide dismutase 1 Homo sapiens 29-49 8453769-0 1993 A methodological approach to superoxide dismutase (SOD) activity assay based on inhibition of nitroblue tetrazolium (NBT) reduction. Nitroblue Tetrazolium 117-120 superoxide dismutase 1 Homo sapiens 51-54 8462021-4 1993 The combined treatment of human myeloid leukemia cells by ara-C and LIF is associated with down-regulation of c-myc gene expression, transcriptional activation of jun/fos gene expression, and features of functional differentiation (e.g., the capability to reduce nitroblue tetrazolium, to express lysozyme, or to display differentiation-related surface receptors including C3bi and the c-fms protein). Nitroblue Tetrazolium 263-284 LIF interleukin 6 family cytokine Homo sapiens 68-71 1482652-3 1992 PEG-GM-CSF was unexpectedly more active than GM-CSF in its ability to prime neutrophils to respond to the synthetic peptide n-formyl-methionyl-leucyl-phenylalanine (FMLP) with an oxidative burst (assessed both by nitroblue tetrazolium reduction and ferricytochrome c reduction). Nitroblue Tetrazolium 213-234 colony stimulating factor 2 Homo sapiens 4-10 1482652-3 1992 PEG-GM-CSF was unexpectedly more active than GM-CSF in its ability to prime neutrophils to respond to the synthetic peptide n-formyl-methionyl-leucyl-phenylalanine (FMLP) with an oxidative burst (assessed both by nitroblue tetrazolium reduction and ferricytochrome c reduction). Nitroblue Tetrazolium 213-234 formyl peptide receptor 1 Homo sapiens 165-169 1419892-7 1992 The results demonstrate that the 3 beta-HSD activity can be measured in a rapid and reliable way by measuring the reduction of nitroblue tetrazolium. Nitroblue Tetrazolium 127-148 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Rattus norvegicus 33-43 1419892-2 1992 A rapid and simple method for measuring the 3 beta-HSD activity has been developed, in which the NADH, generated by 3 beta-HSD, reduced nitroblue tetrazolium to a product with absorption maximum at 560 nm. Nitroblue Tetrazolium 136-157 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Rattus norvegicus 44-54 1326533-6 1992 However, the system showed high O2(-)-generating activity of 31.8 mol/s/mol of cytochrome b558 (52.5% of the original O2(-)-generating activity of the solubilized membranes) in the presence of a nitro blue tetrazolium (NBT) reductase fraction that was separated from the cytochrome b fraction by heparin-Sepharose chromatography. Nitroblue Tetrazolium 195-217 cytochrome b Oryctolagus cuniculus 79-91 1419892-2 1992 A rapid and simple method for measuring the 3 beta-HSD activity has been developed, in which the NADH, generated by 3 beta-HSD, reduced nitroblue tetrazolium to a product with absorption maximum at 560 nm. Nitroblue Tetrazolium 136-157 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 Rattus norvegicus 116-126 1306413-1 1992 Authors studied experimentally PAM NBT reduction function in patients with lung cancer. Nitroblue Tetrazolium 35-38 peptidylglycine alpha-amidating monooxygenase Homo sapiens 31-34 1306413-2 1992 Results indicate that PMN and lymphocyte counts in the lung cancer group are significantly lower than that in the control group, and NBT reduction of PAM is significantly decreased. Nitroblue Tetrazolium 133-136 peptidylglycine alpha-amidating monooxygenase Homo sapiens 150-153 1326533-6 1992 However, the system showed high O2(-)-generating activity of 31.8 mol/s/mol of cytochrome b558 (52.5% of the original O2(-)-generating activity of the solubilized membranes) in the presence of a nitro blue tetrazolium (NBT) reductase fraction that was separated from the cytochrome b fraction by heparin-Sepharose chromatography. Nitroblue Tetrazolium 219-222 cytochrome b Oryctolagus cuniculus 79-91 1323343-2 1992 Continuous exposure of HL-60 cells to GM-CSF induced the cell differentiation that was evaluated by the nitroblue tetrazolium (NBT) reducing activity. Nitroblue Tetrazolium 104-125 colony stimulating factor 2 Homo sapiens 38-44 1323343-2 1992 Continuous exposure of HL-60 cells to GM-CSF induced the cell differentiation that was evaluated by the nitroblue tetrazolium (NBT) reducing activity. Nitroblue Tetrazolium 127-130 colony stimulating factor 2 Homo sapiens 38-44 1312372-7 1992 In some patients, rIFN-gamma therapy was associated with the appearance of a small subset of circulating monocytes (1% to 20%) that were NBT-positive. Nitroblue Tetrazolium 137-140 interferon gamma Rattus norvegicus 18-28 1508958-5 1992 PMA-induced differentiation and nitroblue tetrazolium reduction by PMA-treated cells was only partially inhibited (about 20-30%) by indomethacin and nordihydroguiaretic acid (cyclooxygenase and lipoxygenase inhibitors respectively), but not by superoxide dismutase, catalase or mannitol. Nitroblue Tetrazolium 32-53 catalase Homo sapiens 266-274 1359172-3 1992 IR-CRH was detectable in 21 neuroendocrine tumors (10 PET, four NBT, three CA, two PHEO and two SCLC) at levels of 10-2,700 ng/g wet weight (9.6%). Nitroblue Tetrazolium 64-67 corticotropin releasing hormone Homo sapiens 3-6 1378916-3 1992 Combinations of G-CSF and RA produced a supra-additive increase in the percentage of WEHI-3B D+ cells reducing nitro blue tetrazolium and expressing Mac-1 (CD11b) antigen on the cell surface, two markers of the mature state. Nitroblue Tetrazolium 111-133 colony stimulating factor 3 (granulocyte) Mus musculus 16-21 1352926-3 1992 The chemiluminescence of patient neutrophils activated by C3b-opsonized particles was, consequently, significantly decreased compared with that of control neutrophils, while the respiratory burst assayed by phorbolmyristate acid (PMA) stimulated nitroblue tetrazolium (NBT)-reduction was normal in the patient group. Nitroblue Tetrazolium 246-267 endogenous retrovirus group K member 3 Homo sapiens 58-61 1352926-3 1992 The chemiluminescence of patient neutrophils activated by C3b-opsonized particles was, consequently, significantly decreased compared with that of control neutrophils, while the respiratory burst assayed by phorbolmyristate acid (PMA) stimulated nitroblue tetrazolium (NBT)-reduction was normal in the patient group. Nitroblue Tetrazolium 269-272 endogenous retrovirus group K member 3 Homo sapiens 58-61 2064356-7 1991 PSK stimulated the NBT-reducing activity of mouse peritoneal macrophages and the iodination (incorporation of radioactive iodine into an acid-insoluble fraction) of human peripheral blood polymorphonuclear cells (PMN). Nitroblue Tetrazolium 19-22 TAO kinase 2 Mus musculus 0-3 1311213-10 1992 Rather, three of 10 evaluable nBTs had bcl-2 rearrangements. Nitroblue Tetrazolium 30-34 BCL2 apoptosis regulator Homo sapiens 39-44 1723851-5 1991 The NADH formed in the oxidative deamination of methionine reacts with PMS and NBT to form a blue band on the surface of the gel coincident with glutamine transaminase K activity. Nitroblue Tetrazolium 79-82 kynurenine aminotransferase 1 Rattus norvegicus 145-169 1723851-6 1991 Cysteine S-conjugate beta-lyase activity is detected in the gel by incubating the gel with a reaction mixture containing alpha KMB (to ensure maintenance of the enzyme in the pyridoxal 5"-phosphate form), S-(1,2-dichlorovinyl)-L-cysteine (DCVC), PMS, and NBT. Nitroblue Tetrazolium 255-258 kynurenine aminotransferase 1 Rattus norvegicus 0-31 1768050-1 1991 When mouse resident peritoneal macrophages were cultured with PSK (Krestin), a protein-bound polysaccharide extracted from Coriolus versicolor, they became enlarged and elongated and expressed higher NBT-reducing activity. Nitroblue Tetrazolium 200-203 TAO kinase 2 Mus musculus 62-65 2043477-7 1991 Priming of PMN by GH was confirmed by direct demonstration of a stimulatory effect on reduction of nitroblue tetrazolium. Nitroblue Tetrazolium 99-120 growth hormone 1 Homo sapiens 18-20 1370331-5 1992 The binding of 125I-labeled KW-2228, a muteins of G-CSF, to KU-1 and NBT-2 was inhibited by unlabeled KW-2228 in a dose-dependent manner. Nitroblue Tetrazolium 69-72 colony stimulating factor 3 Homo sapiens 50-55 1954981-2 1991 This study documents that this discrepancy of the CL response to fMLP and PMA remained over a wide range of stimuli concentrations, was not due to iron-deficient PV cells and was also observed with the nitroblue tetrazolium assay. Nitroblue Tetrazolium 202-223 formyl peptide receptor 1 Homo sapiens 65-69 1649124-1 1991 Bombesin, as well as the two mammalian bombesin-like peptides gastrin-releasing peptide and neuromedin C, have been shown in this study to stimulate in vitro all steps of the phagocytic process in murine peritoneal macrophages: adherence to substrate, chemotaxis, ingestion of cells (Candida albicans) and inert particles (latex beads), and production of superoxide anion as measured by nitroblue tetrazolium reduction. Nitroblue Tetrazolium 387-408 gastrin releasing peptide Homo sapiens 0-8 1649124-1 1991 Bombesin, as well as the two mammalian bombesin-like peptides gastrin-releasing peptide and neuromedin C, have been shown in this study to stimulate in vitro all steps of the phagocytic process in murine peritoneal macrophages: adherence to substrate, chemotaxis, ingestion of cells (Candida albicans) and inert particles (latex beads), and production of superoxide anion as measured by nitroblue tetrazolium reduction. Nitroblue Tetrazolium 387-408 gastrin releasing peptide Homo sapiens 92-104 1995312-3 1991 After treatment with DMSO, GM-CSF delayed expression of some HL60 differentiation programs (CD11b expression), but not others (nitro blue tetrazolium dye reduction), and delayed the exit of cells from the cell cycle. Nitroblue Tetrazolium 127-149 colony stimulating factor 2 Homo sapiens 27-33 1856112-5 1991 Both enzymes react to phenazine methosulfate (PMS) which transfers reduction equivalents to the electron acceptor nitroblue tetrazolium chloride (NBT), thus causing a coreaction of GPDH in the demonstration of NAD-GPDH. Nitroblue Tetrazolium 114-144 glycerol-3-phosphate dehydrogenase 1 Rattus norvegicus 181-185 1856112-5 1991 Both enzymes react to phenazine methosulfate (PMS) which transfers reduction equivalents to the electron acceptor nitroblue tetrazolium chloride (NBT), thus causing a coreaction of GPDH in the demonstration of NAD-GPDH. Nitroblue Tetrazolium 114-144 glycerol-3-phosphate dehydrogenase 1 Rattus norvegicus 214-218 1856112-5 1991 Both enzymes react to phenazine methosulfate (PMS) which transfers reduction equivalents to the electron acceptor nitroblue tetrazolium chloride (NBT), thus causing a coreaction of GPDH in the demonstration of NAD-GPDH. Nitroblue Tetrazolium 146-149 glycerol-3-phosphate dehydrogenase 1 Rattus norvegicus 181-185 1856112-5 1991 Both enzymes react to phenazine methosulfate (PMS) which transfers reduction equivalents to the electron acceptor nitroblue tetrazolium chloride (NBT), thus causing a coreaction of GPDH in the demonstration of NAD-GPDH. Nitroblue Tetrazolium 146-149 glycerol-3-phosphate dehydrogenase 1 Rattus norvegicus 214-218 2344669-7 1990 As expected, NBT levels were significantly lower (299 micrograms/g) in tissue that was continuously suffused with superoxide dismutase (SOD) plus catalase (CAT) before occlusion and during reperfusion. Nitroblue Tetrazolium 13-16 catalase Homo sapiens 146-154 2176110-7 1990 By contrast, colonies derived 7 days after a single INF-gamma injection were able to generate superoxide as shown by increased NBT reduction. Nitroblue Tetrazolium 127-130 interferon gamma Homo sapiens 52-61 1705636-5 1991 G-CSF induced TPA- and FMLP-stimulated NBT reduction in the presence of 100 nM RA, but GM-CSF induced only TPA-stimulated NBT reduction. Nitroblue Tetrazolium 39-42 colony stimulating factor 3 Homo sapiens 0-5 1705636-5 1991 G-CSF induced TPA- and FMLP-stimulated NBT reduction in the presence of 100 nM RA, but GM-CSF induced only TPA-stimulated NBT reduction. Nitroblue Tetrazolium 39-42 formyl peptide receptor 1 Homo sapiens 23-27 1705636-5 1991 G-CSF induced TPA- and FMLP-stimulated NBT reduction in the presence of 100 nM RA, but GM-CSF induced only TPA-stimulated NBT reduction. Nitroblue Tetrazolium 122-125 colony stimulating factor 2 Homo sapiens 87-93 2172251-6 1990 When exposed to NBT and NADPH this component of the oxidoreductase generates superoxide independent of cytochrome b. Nitroblue Tetrazolium 16-19 mitochondrially encoded cytochrome b Homo sapiens 103-115 1703196-2 1990 IFN-gamma induced nitro blue tetrazolium (NBT) reducing activity of U-937 cells in a dose-dependent manner, while cAMP-inducing agents such as cholera toxin, prostaglandin E1, forskolin, and isoproterenol only marginally induced NBT reducing activity. Nitroblue Tetrazolium 18-40 interferon gamma Homo sapiens 0-9 1703196-2 1990 IFN-gamma induced nitro blue tetrazolium (NBT) reducing activity of U-937 cells in a dose-dependent manner, while cAMP-inducing agents such as cholera toxin, prostaglandin E1, forskolin, and isoproterenol only marginally induced NBT reducing activity. Nitroblue Tetrazolium 42-45 interferon gamma Homo sapiens 0-9 1703196-2 1990 IFN-gamma induced nitro blue tetrazolium (NBT) reducing activity of U-937 cells in a dose-dependent manner, while cAMP-inducing agents such as cholera toxin, prostaglandin E1, forskolin, and isoproterenol only marginally induced NBT reducing activity. Nitroblue Tetrazolium 229-232 interferon gamma Homo sapiens 0-9 1703196-3 1990 However, they all synergistically increased IFN-gamma induction of NBT reducing activity. Nitroblue Tetrazolium 67-70 interferon gamma Homo sapiens 44-53 2121089-2 1990 This improved assay incorporates detergent and uricase in a more concentrated nitroblue-tetrazolium reagent base compared to the earlier reagent (Johnson & Baker assay), including a new serum calibrator. Nitroblue Tetrazolium 78-99 urate oxidase (pseudogene) Homo sapiens 47-54 2319123-1 1990 An accurately validated method was developed for quantitative determination of succinate dehydrogenase (EC 1.3.99.1; SDH) activity in individual sympathetic neuron perikarya by microdensitometric measurement of an SDH-nitroblue tetrazolium-derived formazan final reaction product. Nitroblue Tetrazolium 218-239 serine dehydratase Rattus norvegicus 117-120 2166023-2 1990 IFN-gamma (100 units/ml) or cholera toxin (10(-9) M) alone only marginally induced various differentiation-associated characteristics such as NBT-reducing activity, phagocytic activity, a-naphthyl acetate esterase activity and surface markers. Nitroblue Tetrazolium 142-145 interferon gamma Homo sapiens 0-9 2319123-1 1990 An accurately validated method was developed for quantitative determination of succinate dehydrogenase (EC 1.3.99.1; SDH) activity in individual sympathetic neuron perikarya by microdensitometric measurement of an SDH-nitroblue tetrazolium-derived formazan final reaction product. Nitroblue Tetrazolium 218-239 serine dehydratase Rattus norvegicus 214-217 2368186-1 1990 A superoxide dismutase (SOD) activity in saliva and gastric juice has been revealed using the NBT reduction and adrenaline autooxidation assays. Nitroblue Tetrazolium 94-97 superoxide dismutase 1 Homo sapiens 2-22 2368186-1 1990 A superoxide dismutase (SOD) activity in saliva and gastric juice has been revealed using the NBT reduction and adrenaline autooxidation assays. Nitroblue Tetrazolium 94-97 superoxide dismutase 1 Homo sapiens 24-27 2181784-3 1990 A recent modification of the Nitroblue Tetrazolium (NBT) reagent, improved by addition of tensides and uricase, exhibits lower interference by lipaemia and urate. Nitroblue Tetrazolium 29-50 urate oxidase (pseudogene) Homo sapiens 103-110 2181784-3 1990 A recent modification of the Nitroblue Tetrazolium (NBT) reagent, improved by addition of tensides and uricase, exhibits lower interference by lipaemia and urate. Nitroblue Tetrazolium 52-55 urate oxidase (pseudogene) Homo sapiens 103-110 2105994-6 1990 However, nitroblue tetrazolium reducing activity was synergistically induced by combinations of TGF-beta 1 and TNF. Nitroblue Tetrazolium 9-30 transforming growth factor beta 1 Homo sapiens 96-106 2105994-6 1990 However, nitroblue tetrazolium reducing activity was synergistically induced by combinations of TGF-beta 1 and TNF. Nitroblue Tetrazolium 9-30 tumor necrosis factor Homo sapiens 111-114 2105994-8 1990 Although IFN-gamma, IL-6, granulocyte CSF, and granulocyte-macrophage CSF-induced nitroblue tetrazolium reducing activity of U-937 cells, only IFN-gamma, and TNF induced it synergistically in combination with TGF-beta 1. Nitroblue Tetrazolium 82-103 interferon gamma Homo sapiens 9-18 2105994-8 1990 Although IFN-gamma, IL-6, granulocyte CSF, and granulocyte-macrophage CSF-induced nitroblue tetrazolium reducing activity of U-937 cells, only IFN-gamma, and TNF induced it synergistically in combination with TGF-beta 1. Nitroblue Tetrazolium 82-103 interleukin 6 Homo sapiens 20-24 2105994-8 1990 Although IFN-gamma, IL-6, granulocyte CSF, and granulocyte-macrophage CSF-induced nitroblue tetrazolium reducing activity of U-937 cells, only IFN-gamma, and TNF induced it synergistically in combination with TGF-beta 1. Nitroblue Tetrazolium 82-103 tumor necrosis factor Homo sapiens 158-161 2105994-8 1990 Although IFN-gamma, IL-6, granulocyte CSF, and granulocyte-macrophage CSF-induced nitroblue tetrazolium reducing activity of U-937 cells, only IFN-gamma, and TNF induced it synergistically in combination with TGF-beta 1. Nitroblue Tetrazolium 82-103 transforming growth factor beta 1 Homo sapiens 209-219 2337663-2 1990 The high level of the nitro-blue tetrazolium salt reduction in individual cells non-contacting with others is reached when using fibronectin or serum-opsonized zymosan but not phorbol myristate acetate or chemotactic formyl-peptide as activators. Nitroblue Tetrazolium 22-49 fibronectin 1 Homo sapiens 129-140 1982480-3 1990 Both human CuZn-superoxide dismutase and host mouse CuZn-superoxide dismutase activities in cultured neurons were identified by native gel electrophoresis followed by nitroblue tetrazolium staining. Nitroblue Tetrazolium 167-188 superoxide dismutase 1 Homo sapiens 11-36 1982480-3 1990 Both human CuZn-superoxide dismutase and host mouse CuZn-superoxide dismutase activities in cultured neurons were identified by native gel electrophoresis followed by nitroblue tetrazolium staining. Nitroblue Tetrazolium 167-188 superoxide dismutase 1 Homo sapiens 52-77 34284182-7 2022 The potential benefits of NBT-reactive compounds on health were evaluated in the in vivo model of C. elegans where they activated the SKN-1/Nrf2 pathway, evidencing the ability of electrophilic compounds to induce a biological response. Nitroblue Tetrazolium 26-29 BZIP domain-containing protein;Protein skinhead-1 Caenorhabditis elegans 134-139 34770929-5 2021 Additionally, the antioxidant action was quantified through the superoxide dismutase (SOD)-like activity, using a protocol based on the inhibitory effect of SOD on the reduction of nitrobluetetrazolium (NBT) by the superoxide anion generated by the xanthine/xanthine oxidase system. Nitroblue Tetrazolium 181-201 superoxide dismutase 1 Homo sapiens 64-84 34770929-5 2021 Additionally, the antioxidant action was quantified through the superoxide dismutase (SOD)-like activity, using a protocol based on the inhibitory effect of SOD on the reduction of nitrobluetetrazolium (NBT) by the superoxide anion generated by the xanthine/xanthine oxidase system. Nitroblue Tetrazolium 181-201 superoxide dismutase 1 Homo sapiens 86-89 34770929-5 2021 Additionally, the antioxidant action was quantified through the superoxide dismutase (SOD)-like activity, using a protocol based on the inhibitory effect of SOD on the reduction of nitrobluetetrazolium (NBT) by the superoxide anion generated by the xanthine/xanthine oxidase system. Nitroblue Tetrazolium 181-201 superoxide dismutase 1 Homo sapiens 157-160 34770929-5 2021 Additionally, the antioxidant action was quantified through the superoxide dismutase (SOD)-like activity, using a protocol based on the inhibitory effect of SOD on the reduction of nitrobluetetrazolium (NBT) by the superoxide anion generated by the xanthine/xanthine oxidase system. Nitroblue Tetrazolium 203-206 superoxide dismutase 1 Homo sapiens 64-84 34770929-5 2021 Additionally, the antioxidant action was quantified through the superoxide dismutase (SOD)-like activity, using a protocol based on the inhibitory effect of SOD on the reduction of nitrobluetetrazolium (NBT) by the superoxide anion generated by the xanthine/xanthine oxidase system. Nitroblue Tetrazolium 203-206 superoxide dismutase 1 Homo sapiens 86-89 34770929-5 2021 Additionally, the antioxidant action was quantified through the superoxide dismutase (SOD)-like activity, using a protocol based on the inhibitory effect of SOD on the reduction of nitrobluetetrazolium (NBT) by the superoxide anion generated by the xanthine/xanthine oxidase system. Nitroblue Tetrazolium 203-206 superoxide dismutase 1 Homo sapiens 157-160