PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 33075723-3 2021 Then, PEI and luminol were simultaneously immobilized on Ni-TCPP (Fe) nanosheets to construct self-enhanced solid state luminophore (Ni-TCPP (Fe)-PEI-Lum), possessing desirable stability and high ECL efficiency. Luminol 14-21 lumican Homo sapiens 150-153 33126179-6 2021 For the ultrasensitive chemiluminescence transduction, we used a contact imaging portable device based on cooled CCD, and measured the light signal resulting from the reaction of the HRP-labelled anti-human IgA with a H2O2/luminol/enhancers substrate. Luminol 223-230 CD79a molecule Homo sapiens 207-210 33076050-4 2021 Meanwhile, g-C3N4 nanosheet loaded with luminol capped AuNPs (Lum-AuNPs@g-C3N4) nanocomposite was used as the ECL signal nanoprobe. Luminol 40-47 lumican Homo sapiens 62-65 33304887-3 2020 The detection depends on ligand replacement from ferrocene (Fc) to Chol through a beta-cyclodextrin (beta-CD)-based host-guest interaction, which releases Fc-Hemin as a catalyst for the luminol/hydrogen peroxide chemical luminescence system. Luminol 186-193 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 101-108 32639722-6 2020 Moreover, the ECL emission of luminol is obviously quenched based on the resonance energy transfer (RET) between luminol as donor and cytochrome c (Cyt c) as acceptor. Luminol 30-37 cytochrome c, somatic Homo sapiens 134-146 32786482-2 2020 In this work, we found that the oxidized g-C3N4 (g-CNOX) could trigger luminol to produce a long-lasting and intense CL emission. Luminol 71-78 ecto-NOX disulfide-thiol exchanger 1 Homo sapiens 51-55 32785352-0 2020 Understanding the ECL interaction of luminol and Ru(bpy)32+ luminophores by spectro-electrochemiluminescence. Luminol 37-44 C-C motif chemokine ligand 21 Homo sapiens 18-21 32785352-1 2020 A detailed analysis of the ECL interaction between luminol and tris(2,2"-bipyridyl)dichlororuthenium(ii) (Ru(bpy)32+) is required before using them in ECL systems for multianalyte detection purposes. Luminol 51-58 C-C motif chemokine ligand 21 Homo sapiens 27-30 32785352-1 2020 A detailed analysis of the ECL interaction between luminol and tris(2,2"-bipyridyl)dichlororuthenium(ii) (Ru(bpy)32+) is required before using them in ECL systems for multianalyte detection purposes. Luminol 51-58 C-C motif chemokine ligand 21 Homo sapiens 151-154 32452394-4 2020 The biosensor exploits three coupled enzymatic reactions catalyzed by AChE, choline oxidase and horseradish peroxidase, leading to production of hydrogen peroxide, which is measured with an optimized luminol substrate. Luminol 200-207 acetylcholinesterase (Cartwright blood group) Homo sapiens 70-74 32639722-6 2020 Moreover, the ECL emission of luminol is obviously quenched based on the resonance energy transfer (RET) between luminol as donor and cytochrome c (Cyt c) as acceptor. Luminol 30-37 cytochrome c, somatic Homo sapiens 148-153 32438803-0 2020 Oxygen Vacancy-Enhanced Electrochemiluminescence Sensing Strategy Using Luminol Thermally Encapsulated in Apoferritin as a Transducer for Biomarker Immunoassay. Luminol 72-79 ferritin heavy chain 1 Homo sapiens 106-117 32601928-5 2020 Finally, BNQDs-N react with luminol - to obtain the excited species AP2-*, returning to ground state and emitting light. Luminol 29-36 transcription factor AP-2 alpha Homo sapiens 69-72 32438803-1 2020 Oxygen vacancies (OVs) enhanced electrochemiluminescence (ECL) biosensing strategy using luminol thermally encapsulated in apoferritin (Lum@apoFt) as an efficient transducer was investigated for ultrasensitive biomarker detection. Luminol 89-96 ferritin heavy chain 1 Homo sapiens 123-134 32438803-1 2020 Oxygen vacancies (OVs) enhanced electrochemiluminescence (ECL) biosensing strategy using luminol thermally encapsulated in apoferritin (Lum@apoFt) as an efficient transducer was investigated for ultrasensitive biomarker detection. Luminol 89-96 lumican Homo sapiens 136-139 32463397-1 2020 In this study, we report a facile one-pot chemical etching approach to simply and rapidly prepare gold nanoclusters capped with luminol (Lum-AuNCs) in an alkaline aqueous solution at room temperature. Luminol 128-135 lumican Homo sapiens 137-140 32463397-4 2020 On the basis of the ligand-induced etching of glutathione (GSH) to the intermediate (luminol capped gold nanoparticles, abbreviated as Lum-AuNPs), a novel and simple method for the fluorescence determination of GSH has been established. Luminol 85-92 lumican Homo sapiens 135-138 32314017-6 2020 Determination of lysozyme was achieved by releasing the luminol-labeled aptamer to generate a chemiluminescence signal at a wavelength of 425 nm. Luminol 56-63 lysozyme Homo sapiens 17-25 32083257-2 2020 A quenching effect of BPNs on luminol ECL was achieved based on ECL resonance energy transfer (ECL-RET) with excited state luminol as the energy donor and BPNs as the energy acceptor. Luminol 30-37 ret proto-oncogene Homo sapiens 99-102 32083257-2 2020 A quenching effect of BPNs on luminol ECL was achieved based on ECL resonance energy transfer (ECL-RET) with excited state luminol as the energy donor and BPNs as the energy acceptor. Luminol 123-130 ret proto-oncogene Homo sapiens 99-102 31848726-0 2019 Aggregation-induced fluorescence of the luminol-terbium(III) complex in polymer nanoparticles for sensitive determination of thrombin. Luminol 40-47 coagulation factor II, thrombin Homo sapiens 125-133 31910856-5 2020 The resulting haptoglobin-hemoglobin complex inhibits the peroxidase-like activity of luminol/H2O2-hemoglobin-MNPs sensing scheme and reduces the chemiluminescence intensities correspondingly to the innate haptoglobin concentrations. Luminol 86-93 haptoglobin Bos taurus 14-25 31910856-5 2020 The resulting haptoglobin-hemoglobin complex inhibits the peroxidase-like activity of luminol/H2O2-hemoglobin-MNPs sensing scheme and reduces the chemiluminescence intensities correspondingly to the innate haptoglobin concentrations. Luminol 86-93 haptoglobin Bos taurus 206-217 31848726-10 2019 Thrombin readily coordinates with the luminol-Tb(III) system, and this results in particle aggregation. Luminol 38-45 coagulation factor II, thrombin Homo sapiens 0-8 31848726-11 2019 The blue fluorescence of luminol increases strongly, and this effect provides the basis for fluorometric determination of thrombin. Luminol 25-32 coagulation factor II, thrombin Homo sapiens 122-130 31382095-1 2019 This work reported a ternary quenching strategy based on electrochemiluminescence resonance energy transfer (ECL-RET) between luminol/H2O2 system and MnO2 capped carbon nanospheres (MnO2@C) and Mn2+ released from the reduction of MnO2 and ascorbic acid (AA) consumed superoxide radical (O2 -) for detection of insulin. Luminol 126-133 insulin Homo sapiens 310-317 31811449-1 2019 The detection of thrombin by using CdS nanocrystals (CdS NCs), gold nanoparticles (AuNPs) and luminol is investigated in this work. Luminol 94-101 coagulation factor II, thrombin Homo sapiens 17-25 31811449-8 2019 In this method, by increasing the concentration of thrombin, the intensity of CdS NCs decreases, while that of luminol increases. Luminol 111-118 coagulation factor II, thrombin Homo sapiens 51-59 31546461-4 2019 AuNP/gelatin/HRP and AuNP/gelatin/LTF nanogels presented an ~11-fold enhancement of bioluminescence in an HRP-luminol system and a ~50-fold fluorescence enhancement when compared to free LTF in cell uptake experiments. Luminol 110-117 lactotransferrin Homo sapiens 34-37 32084645-13 2019 Atosiban pre-treatment elevated MPO activity, luminol and lucigenin chemiluminescence levels (P < 0.01 - 0.001) and cortistatin increased lucigenin and luminol chemiluminescence (P < 0.05 - 0.01). Luminol 155-162 cortistatin Rattus norvegicus 119-130 31595739-0 2019 Synthesis and Application of CeO2/SnS2 Heterostructures as Highly-Efficient Coreaction Accelerator in Luminol-Dissolved O2 System for Ultrasensitive Biomarkers Immunoassay. Luminol 102-109 sodium voltage-gated channel alpha subunit 11 Homo sapiens 34-38 31155854-0 2019 Flow-injection chemiluminescence of the luminol-potassium periodate system enhanced by TGA-capped CdTe quantum dots for the determination of theophylline. Luminol 40-47 T-box transcription factor 1 Homo sapiens 87-90 31155854-1 2019 The chemiluminescence (CL) behaviour of the luminol-potassium periodate system enhanced by CdTe quantum dots capped with thioglycolic acid (TGA-CdTe QDs) was studied using kinetic experiments, CL spectra, UV-vis absorption spectra and fluorescence spectra. Luminol 44-51 T-box transcription factor 1 Homo sapiens 140-143 31539224-4 2019 With H2O2 as coreactant and luminol as ECL active material, ECL imaging of intracellular miRNA-21 in single HeLa cell was obtained by EMCCD. Luminol 28-35 microRNA 21 Homo sapiens 89-97 31382095-3 2019 In order to sensitively detect insulin, labels MnO2@C were used to anchor secondary antibodies via electrostatic interaction and inhibit the ECL intensity of luminol. Luminol 158-165 insulin Homo sapiens 31-38 31382095-6 2019 On the basis of the dual quenching effect of luminol, the sandwich immunosensor was prepared to determine insulin with wide linear range from 0.5 pg mL-1 to 60 ng mL-1 and a low detection limit of 0.13 pg mL-1 (S/N = 3). Luminol 45-52 insulin Homo sapiens 106-113 31382095-6 2019 On the basis of the dual quenching effect of luminol, the sandwich immunosensor was prepared to determine insulin with wide linear range from 0.5 pg mL-1 to 60 ng mL-1 and a low detection limit of 0.13 pg mL-1 (S/N = 3). Luminol 45-52 L1 cell adhesion molecule Mus musculus 149-153 31254862-2 2019 In this paper, we present a simple, label-free and signal-on electrochemiluminescence (ECL) aptasensor for the detection of amyloid-beta (Abeta) peptide using luminol as ECL emitter and in-situ generated reactive oxygen species (ROS) as coreactant via catalytic reaction between Cu2+-Abeta and the dissolved O2 in the presence of ascorbic acid (AA). Luminol 159-166 amyloid beta precursor protein Homo sapiens 124-136 31226604-0 2019 An ultrasensitive luminol cathodic electrochemiluminescence probe with highly porous Pt on ionic liquid functionalized graphene film as platform for carcinoembryonic antigen sensing. Luminol 18-25 CEA cell adhesion molecule 3 Homo sapiens 149-173 31595739-2 2019 Herein, CeO2/SnS2 heterostructures were synthesized and applied as novel coreaction accelerator to enhance the ECL efficiency of luminol-dissolved O2 system for the first time. Luminol 129-136 sodium voltage-gated channel alpha subunit 11 Homo sapiens 13-17 31595739-4 2019 CeO2/SnS2 as a electroactive substrate can remarkably accelerate the generation of abundant superoxide anion radicals (O2 -) to react with luminol anion radical (L -), achieving about 2-fold stronger ECL intensity than pure CeO2 NPs. Luminol 139-146 sodium voltage-gated channel alpha subunit 11 Homo sapiens 5-9 31226604-4 2019 After CEA was incubated with the CEA antibody, the cathodic ECL signal of luminol decreased thanks to the less conductive immunocomplex. Luminol 74-81 CEA cell adhesion molecule 3 Homo sapiens 6-9 31254862-2 2019 In this paper, we present a simple, label-free and signal-on electrochemiluminescence (ECL) aptasensor for the detection of amyloid-beta (Abeta) peptide using luminol as ECL emitter and in-situ generated reactive oxygen species (ROS) as coreactant via catalytic reaction between Cu2+-Abeta and the dissolved O2 in the presence of ascorbic acid (AA). Luminol 159-166 amyloid beta precursor protein Homo sapiens 138-143 31226604-4 2019 After CEA was incubated with the CEA antibody, the cathodic ECL signal of luminol decreased thanks to the less conductive immunocomplex. Luminol 74-81 CEA cell adhesion molecule 3 Homo sapiens 33-36 31254862-2 2019 In this paper, we present a simple, label-free and signal-on electrochemiluminescence (ECL) aptasensor for the detection of amyloid-beta (Abeta) peptide using luminol as ECL emitter and in-situ generated reactive oxygen species (ROS) as coreactant via catalytic reaction between Cu2+-Abeta and the dissolved O2 in the presence of ascorbic acid (AA). Luminol 159-166 amyloid beta precursor protein Homo sapiens 284-289 31254862-2 2019 In this paper, we present a simple, label-free and signal-on electrochemiluminescence (ECL) aptasensor for the detection of amyloid-beta (Abeta) peptide using luminol as ECL emitter and in-situ generated reactive oxygen species (ROS) as coreactant via catalytic reaction between Cu2+-Abeta and the dissolved O2 in the presence of ascorbic acid (AA). Luminol 159-166 amyloid beta precursor protein Homo sapiens 345-347 30928738-0 2019 Quench-type electrochemiluminescence immunosensor for detection of amyloid beta-protein based on resonance energy transfer from luminol@SnS2-Pd to Cu doped WO3 nanoparticles. Luminol 128-135 sodium voltage-gated channel alpha subunit 11 Homo sapiens 136-140 31322849-5 2019 Thus, the biosensor can detect GSK-3beta using luminol as an ECL probe. Luminol 47-54 glycogen synthase kinase 3 alpha Homo sapiens 31-40 30981028-1 2019 In this work, the ZnO nanostars with excellent catalytic performance were firstly used as the coreaction accelerator of luminol-O2 system to construct a biosensor for ultrasensitively detecting microRNA-21 (miRNA-21) in cancer cells. Luminol 120-127 microRNA 21 Homo sapiens 194-205 30981028-1 2019 In this work, the ZnO nanostars with excellent catalytic performance were firstly used as the coreaction accelerator of luminol-O2 system to construct a biosensor for ultrasensitively detecting microRNA-21 (miRNA-21) in cancer cells. Luminol 120-127 microRNA 21 Homo sapiens 207-215 31059237-2 2019 Luminol has been reported to detect myeloperoxidase (MPO) activity in an inflamed area through a light-emitting reaction. Luminol 0-7 myeloperoxidase Homo sapiens 36-51 31059237-2 2019 Luminol has been reported to detect myeloperoxidase (MPO) activity in an inflamed area through a light-emitting reaction. Luminol 0-7 myeloperoxidase Homo sapiens 53-56 31025709-5 2019 Based on the fact that Hg2+ could further enhance the CL intensity in the Pt NPs-luminol CL system, a Pt NPs-catalyzed CL method based on a flow injection system is developed for the sensitive analysis of Hg2+ . Luminol 81-88 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 23-26 31025709-5 2019 Based on the fact that Hg2+ could further enhance the CL intensity in the Pt NPs-luminol CL system, a Pt NPs-catalyzed CL method based on a flow injection system is developed for the sensitive analysis of Hg2+ . Luminol 81-88 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 205-208 30928738-5 2019 In addition, copper doped mesoporous tungsten trioxide (Cu:WO3) nanoparticles were selected to quench ECL emission of luminol@SnS2-Pd via resonance energy transfer, where luminol@SnS2-Pd was the donor and Cu:WO3 was the acceptor. Luminol 118-125 sodium voltage-gated channel alpha subunit 11 Homo sapiens 126-130 30928738-5 2019 In addition, copper doped mesoporous tungsten trioxide (Cu:WO3) nanoparticles were selected to quench ECL emission of luminol@SnS2-Pd via resonance energy transfer, where luminol@SnS2-Pd was the donor and Cu:WO3 was the acceptor. Luminol 118-125 sodium voltage-gated channel alpha subunit 11 Homo sapiens 179-183 30928738-5 2019 In addition, copper doped mesoporous tungsten trioxide (Cu:WO3) nanoparticles were selected to quench ECL emission of luminol@SnS2-Pd via resonance energy transfer, where luminol@SnS2-Pd was the donor and Cu:WO3 was the acceptor. Luminol 171-178 sodium voltage-gated channel alpha subunit 11 Homo sapiens 126-130 30928738-5 2019 In addition, copper doped mesoporous tungsten trioxide (Cu:WO3) nanoparticles were selected to quench ECL emission of luminol@SnS2-Pd via resonance energy transfer, where luminol@SnS2-Pd was the donor and Cu:WO3 was the acceptor. Luminol 171-178 sodium voltage-gated channel alpha subunit 11 Homo sapiens 179-183 30856428-1 2019 This work used 3,4,9,10-perylenetetracarboxylic acid-luminol composite (PTCA-luminol) as signal tag with improved ECL signal and applied cruciform DNA structure mediated exponential strand displacement reaction (SDR) to construct an ultrasensitive electrochemiluminescence (ECL) biosensor for microRNA-21 (miRNA-21) detection. Luminol 53-60 microRNA 21 Homo sapiens 293-304 30771932-3 2019 Herein, we demonstrate a liquid-phase luminol chemiluminescence (CL) system for sensitive detection of haptoglobin (Hp), a predictive APP of BM, by utilizing the binding capacity of hemoglobin (Hb). Luminol 38-45 haptoglobin Bos taurus 103-114 30987423-0 2019 Enhanced Visual Wireless Electrochemiluminescence Immunosensing of Prostate-Specific Antigen Based on the Luminol Loaded into MIL-53(Fe)-NH2 Accelerator and Hydrogen Evolution Reaction Mediation. Luminol 106-113 kallikrein related peptidase 3 Homo sapiens 67-92 30987423-1 2019 A sensitive prostate-specific antigen (PSA) detection method using a visual-readout closed bipolar electrode (BPE) system has been introduced by integration of hydrogen evolution reaction (HER) in cathodic pole and electrochemiluminescence (ECL) of luminol loaded within the MIL-53(Fe)-NH2 (L@MIL-53(Fe)-NH2) in the anodic pole. Luminol 249-256 kallikrein related peptidase 3 Homo sapiens 12-43 30856428-1 2019 This work used 3,4,9,10-perylenetetracarboxylic acid-luminol composite (PTCA-luminol) as signal tag with improved ECL signal and applied cruciform DNA structure mediated exponential strand displacement reaction (SDR) to construct an ultrasensitive electrochemiluminescence (ECL) biosensor for microRNA-21 (miRNA-21) detection. Luminol 53-60 microRNA 21 Homo sapiens 306-314 30519975-1 2019 Surface modified colloidal gold (Au) and silver (Ag) nanoparticles (NPs) were used as efficient quenchers of luminol (LH2) fluorescence either in homogeneous aqueous medium or its noncovalent assembly with bovine serum albumin (BSA). Luminol 109-116 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 Homo sapiens 118-121 30439368-0 2019 Electrochemiluminescent immunosensor for prostate specific antigen based upon luminol functionalized platinum nanoparticles loaded on graphene. Luminol 78-85 kallikrein related peptidase 3 Homo sapiens 41-66 30680992-0 2019 Enhancing Luminol Electrochemiluminescence by Combined Use of Cobalt-Based Metal Organic Frameworks and Silver Nanoparticles and Its Application in Ultrasensitive Detection of Cardiac Troponin I. Luminol 10-17 troponin I3, cardiac type Homo sapiens 176-194 30265970-3 2018 Thus, the ECL signal of the modified electrode in luminol solution decreased significantly owing to the mimetic SOD features of the TA assembled nanoprobe that can eliminate the reactive oxygen species. Luminol 50-57 superoxide dismutase 1 Homo sapiens 112-115 30392661-6 2018 When THR existed, HG-DNAzyme was desorbed from the surface of T-Apt/SiO2@GO@CF and catalyzed the CL system of luminol-H2O2. Luminol 110-117 coagulation factor II, thrombin Homo sapiens 5-8 29784351-3 2018 The AuNPs not only enhanced the ECL signal of luminol, but also acted to immobilize the glutamate decarboxylase (GAD) to build the sensing host. Luminol 46-53 glutamate-ammonia ligase Homo sapiens 88-111 30462511-4 2018 Here, we report on the 10-fold activity enhancement of the GOx-HRP enzyme cascade for the oxidation of luminol, when the enzymes are colocalized on micron-scaled solid scaffolds. Luminol 103-110 hydroxyacid oxidase 1 Homo sapiens 59-62 30224136-3 2018 When ALP-Ab2 was captured by antigen-primary antibody (Ab1) complex, disodium phenyl phosphate (PPNa) generated massive phenol under the catalysis of ALP, markedly inhibiting the chemiluminescence intensity of AuNCs@Peps@luminol. Luminol 221-228 alkaline phosphatase, placental Homo sapiens 5-8 30224136-3 2018 When ALP-Ab2 was captured by antigen-primary antibody (Ab1) complex, disodium phenyl phosphate (PPNa) generated massive phenol under the catalysis of ALP, markedly inhibiting the chemiluminescence intensity of AuNCs@Peps@luminol. Luminol 221-228 alkaline phosphatase, placental Homo sapiens 150-153 30029439-1 2018 In this paper, mesoporous graphite-like carbon nitride (mpg-C3N4) combined with gold nanoparticles (Au NPs) was conducted to construct a luminol-hydrogen peroxide (H2O2) based electrochemiluminescent (ECL) immunosensor for prostate specific antigen (PSA) detection. Luminol 137-144 kallikrein related peptidase 3 Homo sapiens 223-248 29859458-5 2018 After immobilizing the C-peptide antibody, which takes great advantage of AuNPs" binding capacity, this immunosensor can quantify C-peptide using luminol as the ECL probe. Luminol 146-153 insulin Homo sapiens 23-32 29859458-5 2018 After immobilizing the C-peptide antibody, which takes great advantage of AuNPs" binding capacity, this immunosensor can quantify C-peptide using luminol as the ECL probe. Luminol 146-153 insulin Homo sapiens 130-139 29784351-3 2018 The AuNPs not only enhanced the ECL signal of luminol, but also acted to immobilize the glutamate decarboxylase (GAD) to build the sensing host. Luminol 46-53 glutamate-ammonia ligase Homo sapiens 113-116 29915846-0 2018 Aggregation-induced emission of luminol: a novel strategy for fluorescence ratiometric detection of ALP and As(v) with high sensitivity and selectivity. Luminol 32-39 ATHS Homo sapiens 100-103 29759226-1 2018 Luminol-nitrogen doped graphene quantum dot (luminol-NGQDs) nanocomposite was synthesized and a novel electrochemiluminescence resonance energy transfer (ECL-RET) process occurred between luminol as the donor and NGQDs as the acceptor in the composite. Luminol 0-7 ret proto-oncogene Homo sapiens 158-161 29759226-1 2018 Luminol-nitrogen doped graphene quantum dot (luminol-NGQDs) nanocomposite was synthesized and a novel electrochemiluminescence resonance energy transfer (ECL-RET) process occurred between luminol as the donor and NGQDs as the acceptor in the composite. Luminol 45-52 ret proto-oncogene Homo sapiens 158-161 29759226-1 2018 Luminol-nitrogen doped graphene quantum dot (luminol-NGQDs) nanocomposite was synthesized and a novel electrochemiluminescence resonance energy transfer (ECL-RET) process occurred between luminol as the donor and NGQDs as the acceptor in the composite. Luminol 188-195 ret proto-oncogene Homo sapiens 158-161 29759226-2 2018 This ECL-RET effect helped luminol-NGQDs composite produced an anodic ECL signal without coreactants. Luminol 27-34 ret proto-oncogene Homo sapiens 9-12 30056493-0 2018 Teicoplanin-functionalized magnetic beads for detection of Staphylococcus aureus via inhibition of the luminol chemiluminescence by intracellular catalase. Luminol 103-110 AT695_RS10915 Staphylococcus aureus 146-154 30056493-5 2018 Lastly, S. aureus is quantified via the inhibitory effect of released intracellular catalase on a chemiluminescent (CL) system composed of peroxidase, luminol, H2O2 and p-iodophenol because catalase decomposes H2O2. Luminol 151-158 AT695_RS10915 Staphylococcus aureus 84-92 30056493-10 2018 S. aureus can be quantified by measuring the inhibition of luminol chemiluminescence (CL) signal by intracellular catalase. Luminol 59-66 AT695_RS10915 Staphylococcus aureus 114-122 29915846-1 2018 A novel dual-emission fluorescence ratiometric probe of luminol-Tb-GMP CPNPs for highly sensitive and selective detection of ALP and As(v) has been constructed based on the stimulus responsivity of luminol. Luminol 56-63 ATHS Homo sapiens 125-128 29915846-1 2018 A novel dual-emission fluorescence ratiometric probe of luminol-Tb-GMP CPNPs for highly sensitive and selective detection of ALP and As(v) has been constructed based on the stimulus responsivity of luminol. Luminol 198-205 ATHS Homo sapiens 125-128 29414245-3 2018 APEX2-(NG)15-MK is a bona fide agonist of the rat, but not of the human B2R (calcium and c-Fos signaling) and is compatible with the cytochemistry reagent TrueBlue (microscopy), a luminol-based reagent, or 3,3",5,5"-tetramethylbenzidine (luminescence or colourimetric B2R detection, cell well plate format). Luminol 180-187 apurinic/apyrimidinic endodeoxyribonuclease 2 Rattus norvegicus 0-5 29447978-9 2018 The inhibition of the production of reactive oxygen species was checked by luminol-dependent chemiluminescence method after N-formylmethionyl-leucyl-phenylalanine (f-MLP) induction. Luminol 75-82 cysteine and glycine rich protein 3 Homo sapiens 166-169 29414090-2 2018 The excellent performance of the sensor comes from simultaneously fabricated layer by layer structure "target DNA + Hemin / Au-Luminol NPs / DNA* / sl DNA / TGA / QDs / MWNTs / GCE" mode which was based on the enhancing effect of luminol by G-quadruplex / hemin and Au nanoparticles and the quenching effect of CdSe/ZnS by G-quadruplex / hemin. Luminol 230-237 T-box transcription factor 1 Homo sapiens 157-160 29893757-4 2018 According to the ratio of the ECL responses of CdS to luminol, the DNMT1 activity was detected in the range of 1.0-30.0 U mL-1 in buffer solution. Luminol 54-61 DNA methyltransferase 1 Homo sapiens 67-72 29893757-4 2018 According to the ratio of the ECL responses of CdS to luminol, the DNMT1 activity was detected in the range of 1.0-30.0 U mL-1 in buffer solution. Luminol 54-61 L1 cell adhesion molecule Mus musculus 122-126 29501151-6 2018 As a proof of concept and example, the enhancement of the chemiluminescence signal produced by Co(II) on the luminol-H2O2 reaction in alkaline medium was used for illustrating this implementation determining vitamin B12 in pharmaceutical preparations (after mineralization for releasing Co(II)). Luminol 109-116 mitochondrially encoded cytochrome c oxidase II Homo sapiens 95-101 29501151-6 2018 As a proof of concept and example, the enhancement of the chemiluminescence signal produced by Co(II) on the luminol-H2O2 reaction in alkaline medium was used for illustrating this implementation determining vitamin B12 in pharmaceutical preparations (after mineralization for releasing Co(II)). Luminol 109-116 mitochondrially encoded cytochrome c oxidase II Homo sapiens 287-293 29294408-5 2018 We used luminol to generate the chemiluminescence and demonstrated that the compartmentalization of LYS in droplets also comprising gold nanoparticles provided enhanced luminescence. Luminol 8-15 lysozyme Homo sapiens 100-103 28743084-1 2018 A novel and competitive electrochemiluminescence (ECL) aptasensor for prostate specific antigen (PSA) assay was constructed using gold nanorods functionalized graphene oxide (GO@AuNRs) multilabeled with glucose oxidase (GOD) and streptavidin (SA) toward luminol-based ECL system. Luminol 254-261 kallikrein related peptidase 3 Homo sapiens 70-95 29278814-5 2018 Furthermore, the as-obtained Pt@BSA- luminol was not only employed as capture probe to recognize CA15-3 after hybridization with Ab2, but also played a crucial role in acting as ECL signal probe due to the presence of massive luminol. Luminol 37-44 mucin 1, cell surface associated Homo sapiens 97-103 29278814-5 2018 Furthermore, the as-obtained Pt@BSA- luminol was not only employed as capture probe to recognize CA15-3 after hybridization with Ab2, but also played a crucial role in acting as ECL signal probe due to the presence of massive luminol. Luminol 226-233 mucin 1, cell surface associated Homo sapiens 97-103 29332832-4 2018 The SBP on electrode surface displayed strong and stable ECL signal of luminol in the presence of H2O2, which could be used for cTnI detection with a concentration range of 5-30,000pg/mL and a detection limit of 3.3pg/mL. Luminol 71-78 troponin I3, cardiac type Homo sapiens 128-132 29706245-2 2018 Hypochlorous acid produced by myeloperoxidase oxidizes luminol to produce light. Luminol 55-62 myeloperoxidase Mus musculus 30-45 28743084-1 2018 A novel and competitive electrochemiluminescence (ECL) aptasensor for prostate specific antigen (PSA) assay was constructed using gold nanorods functionalized graphene oxide (GO@AuNRs) multilabeled with glucose oxidase (GOD) and streptavidin (SA) toward luminol-based ECL system. Luminol 254-261 kallikrein related peptidase 3 Homo sapiens 97-100 28971668-4 2017 Species of O2 - were identified as primary radicals that triggered the spin-transfer from the triplet state of O2 to the aminobenzene ring of luminol by the aids of Au NCs, leading to an efficient phosphorescence. Luminol 142-149 spindlin 1 Homo sapiens 71-75 28738658-1 2017 In this work, an ultrasensitive chemiluminescence (CL) aptasensor was prepared for thrombin detection based on iron porphyrin catalyzing luminol - hydrogen peroxide luminescence under alkaline conditions, and iron porphyrin was desorbed from chitosan modified magnetic oxide graphene composite (CS@Fe3O4@GO). Luminol 137-144 coagulation factor II, thrombin Homo sapiens 83-91 28875693-7 2017 These luminol doped POPDs were found non-toxic at the used concentrations on THP-1 derived human macrophage cells through methyl tetrazolium (MTT) assay. Luminol 6-13 GLI family zinc finger 2 Homo sapiens 77-82 29026164-7 2017 The stimulation of recipient HEK 293a expressing PTHR1s with the PTH-myc/antibodies combination or with PTH-APEX2 supported the histochemical or luminescent detection of recombinant PTHR1s (TrueBlueTM or luminol-based reagent). Luminol 204-211 parathyroid hormone 1 receptor Homo sapiens 49-54 29026164-7 2017 The stimulation of recipient HEK 293a expressing PTHR1s with the PTH-myc/antibodies combination or with PTH-APEX2 supported the histochemical or luminescent detection of recombinant PTHR1s (TrueBlueTM or luminol-based reagent). Luminol 204-211 parathyroid hormone Homo sapiens 49-52 29026164-7 2017 The stimulation of recipient HEK 293a expressing PTHR1s with the PTH-myc/antibodies combination or with PTH-APEX2 supported the histochemical or luminescent detection of recombinant PTHR1s (TrueBlueTM or luminol-based reagent). Luminol 204-211 parathyroid hormone 1 receptor Homo sapiens 182-187 29026164-8 2017 The PTH-HRP construction was the most sensitive and supported all tested peroxidase co-substrates (TrueBlueTM, tetramethylbenzidine (TMB), luminol, biotin-phenol with streptavidin-Qdots); the 3 latter schemes identified endogenous PTHR1 in the osteoblastic HOS cell line. Luminol 139-146 parathyroid hormone Homo sapiens 4-7 28804681-6 2017 Both reactions were inhibited by superoxide dismutase (SOD), but not by catalase, confirming that superoxide anion, and not hydrogen peroxide, is the species oxidizing luminol to produce chemiluminescence. Luminol 168-175 superoxide dismutase 1 Homo sapiens 33-53 28347966-0 2017 A novel aptasensor for lysozyme based on electrogenerated chemiluminescence resonance energy transfer between luminol and silicon quantum dots. Luminol 110-117 lysozyme Homo sapiens 23-31 28347966-2 2017 The results revealed that SiQDs can not only greatly enhance luminol ECL, but also act as energy acceptor to construct a novel ECL resonance energy transfer (ECL-RET) system with luminol. Luminol 61-68 ret proto-oncogene Homo sapiens 162-165 28347966-2 2017 The results revealed that SiQDs can not only greatly enhance luminol ECL, but also act as energy acceptor to construct a novel ECL resonance energy transfer (ECL-RET) system with luminol. Luminol 179-186 ret proto-oncogene Homo sapiens 162-165 28804681-6 2017 Both reactions were inhibited by superoxide dismutase (SOD), but not by catalase, confirming that superoxide anion, and not hydrogen peroxide, is the species oxidizing luminol to produce chemiluminescence. Luminol 168-175 superoxide dismutase 1 Homo sapiens 55-58 28804681-8 2017 Myeloperoxidase (MPO), isolated from human neutrophils, was also able to enhance the superoxide- and hydrogen peroxide-dependent luminol-amplified chemiluminescence. Luminol 129-136 myeloperoxidase Homo sapiens 0-15 28804681-8 2017 Myeloperoxidase (MPO), isolated from human neutrophils, was also able to enhance the superoxide- and hydrogen peroxide-dependent luminol-amplified chemiluminescence. Luminol 129-136 myeloperoxidase Homo sapiens 17-20 28804681-9 2017 The production of ROS by stimulated human neutrophils was detected by luminol-amplified chemiluminescence, which was only partially inhibited by SOD and catalase. Luminol 70-77 superoxide dismutase 1 Homo sapiens 145-148 28804681-9 2017 The production of ROS by stimulated human neutrophils was detected by luminol-amplified chemiluminescence, which was only partially inhibited by SOD and catalase. Luminol 70-77 catalase Homo sapiens 153-161 28804681-10 2017 Interestingly, adding HRPO to stimulated neutrophils increased the luminol-amplified chemiluminescence, which was strongly inhibited by SOD, but not by catalase. Luminol 67-74 superoxide dismutase 1 Homo sapiens 136-139 28029038-1 2017 A mutiplex cytosensor based on a dual electrochemiluminescence (ECL) signal system was fabricated for in situ and simultaneous detection of the expression levels of multiple cell-surface receptors, mannose and epidermal growth factor receptor (EGFR), using luminol-capped gold nanoparticles (Au@luminol) and CdS quantum dots (CdS QDs) as potential-resolved ECL nanoprobes. Luminol 257-264 epidermal growth factor receptor Homo sapiens 244-248 28497690-5 2017 IFN-gamma-antibody (Ab)1 and IL-2-Ab1 were separately immobilized on the two sensing areas to capture the corresponding LTBI markers, which were further recognized by IFN-gamma-Ab2 and IL-2-Ab2 labeled as MB@Au@CQDs and MB@Au@luminol. Luminol 226-233 interferon gamma Homo sapiens 0-9 28192953-4 2017 As compared with the traditional used Au nanoparticles modified with luminol, ~740-fold increase of self-luminescence was observed from this new complex so that CEA antigen as low as 0.5 amol at electrode surface was measurable in the absence of any coreactant. Luminol 69-76 CEA cell adhesion molecule 3 Homo sapiens 161-164 27933682-1 2017 The intermolecular electrochemiluminescence resonance energy transfer (ECL-RET) between luminol and Ru(bpy)32+ was studied extensively to achieve the sensitive bioanalysis owing to the perfect spectral overlap of the donor and acceptor, but it still suffers from the challenging issue of low energy-transfer efficiency. Luminol 88-95 ret proto-oncogene Homo sapiens 75-78 27933682-2 2017 The intramolecular ECL-RET towards the novel ECL compound containing the donor of luminol and the acceptor of Ru(bpy)2 (mcpbpy)2+ (Lum-Ru) was designed and investigated. Luminol 82-89 ret proto-oncogene Homo sapiens 23-26 27933682-3 2017 With the high-efficient ECL-RET in one molecule, the highly intense ECL signal of Lum-Ru was obtained owing to the short path of energy transmission and less energy loss between luminol and Ru(bpy)2 (mcpbpy)2+ . Luminol 178-185 ret proto-oncogene Homo sapiens 28-31 28029038-1 2017 A mutiplex cytosensor based on a dual electrochemiluminescence (ECL) signal system was fabricated for in situ and simultaneous detection of the expression levels of multiple cell-surface receptors, mannose and epidermal growth factor receptor (EGFR), using luminol-capped gold nanoparticles (Au@luminol) and CdS quantum dots (CdS QDs) as potential-resolved ECL nanoprobes. Luminol 295-302 epidermal growth factor receptor Homo sapiens 244-248 27145690-1 2016 In this work, ceria doped ZnO nanomaterials with flower-structure (Ce:ZONFs) were prepared to construct a luminol-based electrochemiluminescence (ECL) immunosensor for amyloid-beta protein (Abeta) detection. Luminol 106-113 amyloid beta precursor protein Homo sapiens 190-195 27435830-6 2016 The ratiometric ECL aptasensor self-calibrated by the internal reference (luminol or QDs) exhibits ultrasensitive and accurate analytical performance toward thrombin (TB) with a linear detection range from 100 ng/mL to 0.5 pg/mL and a detection limit of 4.2 fg/mL [defined as signal-to-noise ratio (S/N) = 3]. Luminol 74-81 coagulation factor II, thrombin Homo sapiens 157-165 27299777-5 2016 Their performance was corroborated with two innovative proofs-of-concept that centered on the luminol transduction chemistry: a first time reported ECL assay based on the enzymatic reaction between an indoxyl substrate and the enzyme alkaline phosphatase, and the electrochemiluminescence resonance energy transfer (ECL-RET) process triggered by the electro-oxidized luminol to the acceptor fluorescein. Luminol 94-101 ret proto-oncogene Homo sapiens 320-323 27299777-8 2016 Graphical abstract Schematic representation of the ECL-RET: from luminol-H2O2 system to fluorescein, the micro-spectrometer for the light collection and the 3D representation of the ECL-RET reaction. Luminol 65-72 ret proto-oncogene Homo sapiens 55-58 27797335-1 2016 In the blood of children (n=16) with large thermal skin burns (> 20% of total body surface), luminol-dependent chemiluminescence (CL) of neutrophils stimulated with phorbol-12-myristate-13-acetate (PMA) and myeloperoxidase (MPO) activity in neutrophils and plasma were assayed in the early period (1-7 post-burn days). Luminol 96-103 myeloperoxidase Homo sapiens 210-225 27797335-1 2016 In the blood of children (n=16) with large thermal skin burns (> 20% of total body surface), luminol-dependent chemiluminescence (CL) of neutrophils stimulated with phorbol-12-myristate-13-acetate (PMA) and myeloperoxidase (MPO) activity in neutrophils and plasma were assayed in the early period (1-7 post-burn days). Luminol 96-103 myeloperoxidase Homo sapiens 227-230 27145690-6 2016 Subsequently, the luminol functionalized Ce:ZONFs (Ce:ZONFs-Lum) were covered by secondary antibody (Ab2) and glucose oxidase (GOD), respectively, to construct a novel Ab2 bioconjugate (Ab2-GOD@Ce:ZONFs-Lum). Luminol 18-25 lumican Homo sapiens 60-63 27145690-6 2016 Subsequently, the luminol functionalized Ce:ZONFs (Ce:ZONFs-Lum) were covered by secondary antibody (Ab2) and glucose oxidase (GOD), respectively, to construct a novel Ab2 bioconjugate (Ab2-GOD@Ce:ZONFs-Lum). Luminol 18-25 lumican Homo sapiens 203-206 26476013-1 2016 This work developed a CdS/MoS2 heterojunction-based photoelectrochemical biosensor for sensitive detection of DNA under the enhanced chemiluminescence excitation of luminol catalyzed by hemin-DNA complex. Luminol 165-172 CDP-diacylglycerol synthase 1 Homo sapiens 22-25 26686921-3 2016 In the presence of AChE and choline oxidase (ChOx), acetylcholine (ATCl) is hydrolyzed by AChE to generate thiocholine, then thiocholine is catalyzed by ChOx to produce H2O2 in situ, which serves as the coreactant to effectively enhance the ECL intensity in luminol-ECL system. Luminol 258-265 acetylcholinesterase (Cartwright blood group) Homo sapiens 19-23 26686921-3 2016 In the presence of AChE and choline oxidase (ChOx), acetylcholine (ATCl) is hydrolyzed by AChE to generate thiocholine, then thiocholine is catalyzed by ChOx to produce H2O2 in situ, which serves as the coreactant to effectively enhance the ECL intensity in luminol-ECL system. Luminol 258-265 acetylcholinesterase (Cartwright blood group) Homo sapiens 90-94 27091590-1 2016 A novel label-free electrochemiluminescence (ECL) immunosensor based on luminol functional-Au NPs@polypyrrole has been developed for the detection of carcinoembryonic antigen (CEA). Luminol 72-79 CEA cell adhesion molecule 3 Homo sapiens 150-174 27091590-1 2016 A novel label-free electrochemiluminescence (ECL) immunosensor based on luminol functional-Au NPs@polypyrrole has been developed for the detection of carcinoembryonic antigen (CEA). Luminol 72-79 CEA cell adhesion molecule 3 Homo sapiens 176-179 26397422-2 2016 The method relied on the interaction of fibrinogen (Fib) with AuNPs and the aggregated AuNPs induce a strong luminol-H2O2 chemiluminesecence (CL) signal. Luminol 109-116 fibrinogen beta chain Homo sapiens 40-50 26397422-2 2016 The method relied on the interaction of fibrinogen (Fib) with AuNPs and the aggregated AuNPs induce a strong luminol-H2O2 chemiluminesecence (CL) signal. Luminol 109-116 fibrinogen beta chain Homo sapiens 52-55 26397422-8 2016 This allows us to utilize the luminol-H2O2 CL system for quantitative analysis of thrombin, which was used to denote fibrosis degree of Fib. Luminol 30-37 coagulation factor II, thrombin Homo sapiens 82-90 26397422-8 2016 This allows us to utilize the luminol-H2O2 CL system for quantitative analysis of thrombin, which was used to denote fibrosis degree of Fib. Luminol 30-37 fibrinogen beta chain Homo sapiens 136-139 26278045-6 2016 With the assistant of glucose oxidase (GOx), the released glucose can react with the dissolved oxgen to produce gluconic acid and H2O2, the latter can enhance the CL of luminol in the NaOH solution. Luminol 169-176 hydroxyacid oxidase 1 Homo sapiens 22-37 26278045-6 2016 With the assistant of glucose oxidase (GOx), the released glucose can react with the dissolved oxgen to produce gluconic acid and H2O2, the latter can enhance the CL of luminol in the NaOH solution. Luminol 169-176 hydroxyacid oxidase 1 Homo sapiens 39-42 26105513-1 2015 A label-free and enzyme-free demultiplexer system for the fabrication of 1:2 molecular demultiplexer with luminol functionalized gold nanoparticles (Lum-AuNPs) as signal transducers was developed for the first time. Luminol 106-113 lumican Homo sapiens 149-152 26653448-0 2016 Employment of bromophenol red and bovine serum albumin as luminol signal co-enhancer in chemiluminescent detection of sequence-specific DNA. Luminol 58-65 albumin Homo sapiens 41-54 26459032-8 2015 CONCLUSION: We show for the first time that inhibition of intragranular MPO activity, or neutralization of intragranular MPO-processed ROS by luminol effectively block NET formation. Luminol 142-149 myeloperoxidase Homo sapiens 121-124 26356088-3 2015 Both single and double modifications of the tyrosine residue occurred in the reaction of angiotensin II with N-methylated luminol derivative 9. Luminol 122-129 angiotensinogen Homo sapiens 89-103 26095306-3 2015 The mixture of the AuNPs-aptamer-IgE complex and the unbounded AuNPs-aptamer could be effectively separated by CE and sensitively detected with luminol-H2 O2 CL system. Luminol 144-151 immunoglobulin heavy constant epsilon Homo sapiens 33-36 26095306-4 2015 By taking the advantage of the excellent catalytic behavior of AuNPs on luminol-H2 O2 CL system, the ultrasensitive detection of IgE was achieved. Luminol 72-79 immunoglobulin heavy constant epsilon Homo sapiens 129-132 25950936-0 2015 Electrochemiluminescence immunosensor based on multifunctional luminol-capped AuNPs@Fe3O4 nanocomposite for the detection of mucin-1. Luminol 63-70 mucin 1, cell surface associated Homo sapiens 125-132 25950936-1 2015 In this work, a novel and multifunctional nanocomposite of luminol capped gold modified Fe3O4 (Lu-AuNPs@Fe3O4) was utilized as the carrier of secondary antibody (Ab2) to fabricate a sandwiched electrochemiluminescence (ECL) immunosensor for ultrasensitive detection of mucin-1 (MUC1). Luminol 59-66 mucin 1, cell surface associated Homo sapiens 269-276 25950936-1 2015 In this work, a novel and multifunctional nanocomposite of luminol capped gold modified Fe3O4 (Lu-AuNPs@Fe3O4) was utilized as the carrier of secondary antibody (Ab2) to fabricate a sandwiched electrochemiluminescence (ECL) immunosensor for ultrasensitive detection of mucin-1 (MUC1). Luminol 59-66 mucin 1, cell surface associated Homo sapiens 278-282 26105513-5 2015 Meanwhile, H2O2 could react with Lum-AuNPs, producing a strong CL emission owing to the enhancement effect of RSH on AuNPs-luminol-H2O2 CL system. Luminol 123-130 lumican Homo sapiens 33-36 25986322-1 2015 Anionic tobacco peroxidase (TOP) is extremely active in chemiluminescence reaction of luminol oxidation without addition of enhancers and more stable than horseradish peroxidase under antibody conjugation conditions. Luminol 86-93 lignin-forming anionic peroxidase-like Nicotiana tabacum 16-26 25428294-1 2015 N-Acetyl-L-cysteine (NAC) can inhibit the luminol-H2 O2 , reaction, which is catalyzed by silver nanoparticles. Luminol 42-49 X-linked Kx blood group Homo sapiens 21-24 26154162-2 2015 First, the comparative study on the enhancement effect of ten compounds as enhancers to the luminol-H2O2-HRP chemiluminescence system was carried out, and the results showed that 4-(imidazol-1-yl)phenol (4-IMP), 4-iodophenol (4-IOP), 4-bromophenol (4-BOP) and 4-hydroxy-4"-iodobiphenyl (HIOP) had the best performance. Luminol 92-99 BOP Homo sapiens 251-254 26154162-4 2015 Subsequently, the influences of pH, ionic strength, HRP, 4-IMP, 4-IOP, 4-BOP, HIOP, H2O2 and luminol on the stabilization of the luminol-H2O2-HRP chemiluminescence system were studied, and we found that pH value, ionic strength, 4-IMP, 4-IOP, 4-BOP, HIOP, H2O2 and luminol have little influence on luminescent stabilization, while HRP has a great influence. Luminol 129-136 BOP Homo sapiens 73-76 26154162-4 2015 Subsequently, the influences of pH, ionic strength, HRP, 4-IMP, 4-IOP, 4-BOP, HIOP, H2O2 and luminol on the stabilization of the luminol-H2O2-HRP chemiluminescence system were studied, and we found that pH value, ionic strength, 4-IMP, 4-IOP, 4-BOP, HIOP, H2O2 and luminol have little influence on luminescent stabilization, while HRP has a great influence. Luminol 129-136 BOP Homo sapiens 245-248 26154162-4 2015 Subsequently, the influences of pH, ionic strength, HRP, 4-IMP, 4-IOP, 4-BOP, HIOP, H2O2 and luminol on the stabilization of the luminol-H2O2-HRP chemiluminescence system were studied, and we found that pH value, ionic strength, 4-IMP, 4-IOP, 4-BOP, HIOP, H2O2 and luminol have little influence on luminescent stabilization, while HRP has a great influence. Luminol 129-136 BOP Homo sapiens 73-76 26154162-4 2015 Subsequently, the influences of pH, ionic strength, HRP, 4-IMP, 4-IOP, 4-BOP, HIOP, H2O2 and luminol on the stabilization of the luminol-H2O2-HRP chemiluminescence system were studied, and we found that pH value, ionic strength, 4-IMP, 4-IOP, 4-BOP, HIOP, H2O2 and luminol have little influence on luminescent stabilization, while HRP has a great influence. Luminol 129-136 BOP Homo sapiens 245-248 25935222-5 2015 For the recognition of each amino acid (here, serine, proline, glycine, asparagine, leucine, and histidine), the corresponding aminoacyl-tRNA synthetase (aaRS) was employed, and multiple enzymatic reactions were combined with a luminol chemiluminescence reaction. Luminol 228-235 alanyl-tRNA synthetase 1 Homo sapiens 127-152 25935222-5 2015 For the recognition of each amino acid (here, serine, proline, glycine, asparagine, leucine, and histidine), the corresponding aminoacyl-tRNA synthetase (aaRS) was employed, and multiple enzymatic reactions were combined with a luminol chemiluminescence reaction. Luminol 228-235 alanyl-tRNA synthetase 1 Homo sapiens 154-158 25856712-5 2015 We assessed resting and fMLP-dependent changes of intracellular calcium concentration ([Ca(2+)]i) in PMNs with the Fura-2AM method and measured fMLP-induced luminol enhanced whole blood chemiluminescence (fMLP-LBCL). Luminol 157-164 formyl peptide receptor 1 Homo sapiens 144-148 26656813-2 2015 The method was based on the inhibitory effect of SIN on the CL reaction of luminol and K3Fe(CN)6 in an alkaline solution, which was sensitized by CdTe/CdS quantum dots (QDs). Luminol 75-82 CDP-diacylglycerol synthase 1 Homo sapiens 151-154 24830367-9 2015 The possible CL reaction mechanism of potassium ferricyanide-luminol-beta2 adrenergic agonist was discussed from the UV/vis spectra. Luminol 61-68 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 69-74 25051535-0 2015 Sensitive electrochemiluminescence detection for CA15-3 based on immobilizing luminol on dendrimer functionalized ZnO nanorods. Luminol 78-85 mucin 1, cell surface associated Homo sapiens 49-55 25022493-2 2015 Electrogenerated chemiluminescence (ECL) of luminol was investigated at the GNP/GR modified glassy carbon electrode (GNP/GR/GCE) and the GNP modified glassy carbon electrode (GNP/GCE) in aqueous solution respectively. Luminol 44-51 aminomethyltransferase Homo sapiens 124-127 25022493-4 2015 The intensity of the anodic ECL at the GNP/GR/GCE is weaker than that at the GNP/GCE, which should be due to the synergic effect of the enhancing effect of gold nanoparticles and the inhibiting effect of graphene on anodic luminol ECL. Luminol 223-230 aminomethyltransferase Homo sapiens 46-49 25022493-4 2015 The intensity of the anodic ECL at the GNP/GR/GCE is weaker than that at the GNP/GCE, which should be due to the synergic effect of the enhancing effect of gold nanoparticles and the inhibiting effect of graphene on anodic luminol ECL. Luminol 223-230 aminomethyltransferase Homo sapiens 81-84 25433682-5 2015 In the presence of glucose in the detection solution, GOx catalyzed glucose to generate H2O2 in situ, which served as a co-reactant of luminol to enhance ECL signal of luminol. Luminol 135-142 hydroxyacid oxidase 1 Homo sapiens 54-57 25433682-5 2015 In the presence of glucose in the detection solution, GOx catalyzed glucose to generate H2O2 in situ, which served as a co-reactant of luminol to enhance ECL signal of luminol. Luminol 168-175 hydroxyacid oxidase 1 Homo sapiens 54-57 25856712-5 2015 We assessed resting and fMLP-dependent changes of intracellular calcium concentration ([Ca(2+)]i) in PMNs with the Fura-2AM method and measured fMLP-induced luminol enhanced whole blood chemiluminescence (fMLP-LBCL). Luminol 157-164 formyl peptide receptor 1 Homo sapiens 144-148 25313990-1 2014 A multi-functional luminol-reduced Pt@Au hybrid flower-like nanocomposite (luminol-Pt@AuNF) which not only acts as an efficient signal probe but also constitutes a pseudobienzyme amplifying system with choline oxidase (ChOx) was firstly synthesized and applied to the construction of a solid-state luminol electrochemiluminescence (ECL) immunosensor for cardiac troponin I (cTnI) detection. Luminol 19-26 troponin I3, cardiac type Homo sapiens 354-372 25313990-1 2014 A multi-functional luminol-reduced Pt@Au hybrid flower-like nanocomposite (luminol-Pt@AuNF) which not only acts as an efficient signal probe but also constitutes a pseudobienzyme amplifying system with choline oxidase (ChOx) was firstly synthesized and applied to the construction of a solid-state luminol electrochemiluminescence (ECL) immunosensor for cardiac troponin I (cTnI) detection. Luminol 19-26 troponin I3, cardiac type Homo sapiens 374-378 25313990-1 2014 A multi-functional luminol-reduced Pt@Au hybrid flower-like nanocomposite (luminol-Pt@AuNF) which not only acts as an efficient signal probe but also constitutes a pseudobienzyme amplifying system with choline oxidase (ChOx) was firstly synthesized and applied to the construction of a solid-state luminol electrochemiluminescence (ECL) immunosensor for cardiac troponin I (cTnI) detection. Luminol 75-82 troponin I3, cardiac type Homo sapiens 354-372 25313990-1 2014 A multi-functional luminol-reduced Pt@Au hybrid flower-like nanocomposite (luminol-Pt@AuNF) which not only acts as an efficient signal probe but also constitutes a pseudobienzyme amplifying system with choline oxidase (ChOx) was firstly synthesized and applied to the construction of a solid-state luminol electrochemiluminescence (ECL) immunosensor for cardiac troponin I (cTnI) detection. Luminol 75-82 troponin I3, cardiac type Homo sapiens 374-378 25313990-1 2014 A multi-functional luminol-reduced Pt@Au hybrid flower-like nanocomposite (luminol-Pt@AuNF) which not only acts as an efficient signal probe but also constitutes a pseudobienzyme amplifying system with choline oxidase (ChOx) was firstly synthesized and applied to the construction of a solid-state luminol electrochemiluminescence (ECL) immunosensor for cardiac troponin I (cTnI) detection. Luminol 75-82 troponin I3, cardiac type Homo sapiens 354-372 25313990-1 2014 A multi-functional luminol-reduced Pt@Au hybrid flower-like nanocomposite (luminol-Pt@AuNF) which not only acts as an efficient signal probe but also constitutes a pseudobienzyme amplifying system with choline oxidase (ChOx) was firstly synthesized and applied to the construction of a solid-state luminol electrochemiluminescence (ECL) immunosensor for cardiac troponin I (cTnI) detection. Luminol 75-82 troponin I3, cardiac type Homo sapiens 374-378 25345916-4 2014 PMN or purified myeloperoxidase (MPO) triggers formation of reactive oxygen species (ROS), quantified by light emission from oxidized luminol. Luminol 134-141 myeloperoxidase Homo sapiens 16-31 25345916-4 2014 PMN or purified myeloperoxidase (MPO) triggers formation of reactive oxygen species (ROS), quantified by light emission from oxidized luminol. Luminol 134-141 myeloperoxidase Homo sapiens 33-36 24915973-4 2014 Myeloperoxidase activity was measured by luminol-dependent chemiluminescence. Luminol 41-48 myeloperoxidase Homo sapiens 0-15 25361206-0 2014 Electrogenerated chemiluminescence resonance energy transfer between luminol and CdSe@ZnS quantum dots and its sensing application in the determination of thrombin. Luminol 69-76 coagulation factor II, thrombin Homo sapiens 155-163 25361206-1 2014 In this work, electrogenerated chemiluminescence resonance energy transfer (ECL-RET) between luminol as a donor and CdSe@ZnS quantum dots (QDs) as an acceptor was reported in neutral conditions. Luminol 93-100 ret proto-oncogene Homo sapiens 80-83 25361206-4 2014 Another stronger anodic ECL peak observed at more positive potential (1.10 V) could be assigned to the ECL-RET between the excited state of luminol and the QDs. Luminol 140-147 ret proto-oncogene Homo sapiens 107-110 25127574-1 2014 In general, the chemiluminescence (CL) sensing of vitamin B12 is achieved by determining Co(II) liberated from acidified vitamin B12 by a luminol system. Luminol 138-145 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 58-61 25127574-1 2014 In general, the chemiluminescence (CL) sensing of vitamin B12 is achieved by determining Co(II) liberated from acidified vitamin B12 by a luminol system. Luminol 138-145 mitochondrially encoded cytochrome c oxidase II Homo sapiens 89-95 25127574-1 2014 In general, the chemiluminescence (CL) sensing of vitamin B12 is achieved by determining Co(II) liberated from acidified vitamin B12 by a luminol system. Luminol 138-145 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 129-132 25127574-2 2014 However, the luminol system for sensing vitamin B12 has poor selectivity due to serious interference from other metal ions. Luminol 13-20 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 48-51 25127574-8 2014 To the best of our knowledge, this is the first report on the CL sensing of vitamin B12 with high selectivity in the absence of luminol. Luminol 128-135 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 84-87 24769071-0 2014 Enhanced electrochemiluminescence from luminol at carboxyl graphene for detection of alpha-fetoprotein. Luminol 39-46 alpha fetoprotein Homo sapiens 85-102 25065314-0 2014 Effect of oxidatively modified and non-modified human serum albumin on luminol-dependent chemiluminescence of human peripheral blood leukocytes stimulated with opsonized zymosan. Luminol 71-78 albumin Homo sapiens 60-67 25065314-1 2014 We studied the effects of native and oxidized human serum albumin on luminol-dependent chemiluminescence of human peripheral blood leukocytes stimulated with opsonized zymosan. Luminol 69-76 albumin Homo sapiens 58-65 25065314-5 2014 In control to non-modified albumin, oxidized albumin produced an inhibitory effect on luminol-dependent chemiluminescence of leukocytes. Luminol 86-93 albumin Homo sapiens 27-34 25065314-5 2014 In control to non-modified albumin, oxidized albumin produced an inhibitory effect on luminol-dependent chemiluminescence of leukocytes. Luminol 86-93 albumin Homo sapiens 45-52 24491761-3 2014 The GOx assembled on the nanoprobe can catalyze glucose to generate H2O2 in the presence of O2 while the ECL reaction occurred in the luminol ECL biosensor. Luminol 134-141 hydroxyacid oxidase 1 Homo sapiens 4-7 24240164-1 2014 A novel and ultrasensitive electrochemiluminescence (ECL) immunosensor, which was based on the amplifying ECL of luminol by hemin-reduced graphene oxide (hemin-rGO) and Ag nanoparticles (AgNPs) decorated reduced graphene oxide (Ag-rGO), was constructed for the detection of carcinoembryonic antigen (CEA). Luminol 113-120 CEA cell adhesion molecule 3 Homo sapiens 274-298 24240164-1 2014 A novel and ultrasensitive electrochemiluminescence (ECL) immunosensor, which was based on the amplifying ECL of luminol by hemin-reduced graphene oxide (hemin-rGO) and Ag nanoparticles (AgNPs) decorated reduced graphene oxide (Ag-rGO), was constructed for the detection of carcinoembryonic antigen (CEA). Luminol 113-120 CEA cell adhesion molecule 3 Homo sapiens 300-303 24115126-1 2014 A boronate ACE coupled with chemiluminescence (CL) detection was developed for sensitive determination of three isomeric benzenediols, which was based on the principle of an inhibited effect of borate complexation on the CL reaction between luminol and potassium hexacyanoferrate (K3 Fe(CN)6 ) in alkaline solution. Luminol 241-248 angiotensin I converting enzyme Homo sapiens 11-14 24491761-4 2014 At a higher concentration of kinase, there are more nanoprobes on the electrode, which gives a higher amount of GOx at the electrode interface and thus higher electrocatalytic efficiency to the luminol ECL reaction. Luminol 194-201 hydroxyacid oxidase 1 Homo sapiens 112-115 25117282-6 2014 Here, we describe a luminol-based ROS Re-elicitation Assay that can be utilized to quantitatively assess flg22-signaling competency of FLS2 at times during which FLS2 is internalized, trafficked through endosomal compartments, and degraded in response to flg22. Luminol 20-27 Leucine-rich receptor-like protein kinase family protein Arabidopsis thaliana 135-139 25013355-6 2014 PAF-induced ROS production and L-selectin shedding were measured in vitro in bovine neutrophils by a luminol chemiluminescence assay and flow cytometry, respectively. Luminol 101-108 PCNA-associated factor Bos taurus 0-3 25117282-6 2014 Here, we describe a luminol-based ROS Re-elicitation Assay that can be utilized to quantitatively assess flg22-signaling competency of FLS2 at times during which FLS2 is internalized, trafficked through endosomal compartments, and degraded in response to flg22. Luminol 20-27 Leucine-rich receptor-like protein kinase family protein Arabidopsis thaliana 162-166 24080119-5 2013 Self-generated O2(*-) during oxidation of L-012 and luminol analogs artifactually induce CL inhibitable by SOD. Luminol 52-59 superoxide dismutase 1 Homo sapiens 107-110 23973428-4 2013 Pyrophosphate released by the amino acid-aaRS binding reaction was detected by luminol chemiluminescence; the method provided selective quantitation of 1.0-30 muM histidine and 1.0-60 muM lysine. Luminol 79-86 alanyl-tRNA synthetase 1 Homo sapiens 41-45 24245883-6 2013 Treatment of the hydrated drink mixes with the enzyme catalase almost completely inhibited the luminol-enhanced luminescence from the hydrated drink mix demonstrating that hydrogen peroxide generated via a chemical reaction among the drink mixes" ingredients was a primary reactive oxygen species (ROS). Luminol 95-102 catalase Homo sapiens 54-62 23726099-1 2013 In the present study, a novel and ultrasensitive electrochemiluminescence (ECL) immunosensor based on luminol cathodic ECL was fabricated by using Au nanoparticles and Pt nanoparticles (nano-AuPt) electrodeposited on graphene-carbon nanotubes nanocomposite as platform for the detection of carcinoembryonic antigen (CEA). Luminol 102-109 CEA cell adhesion molecule 3 Homo sapiens 290-314 23978851-6 2013 Luminol specifically reacts with the superoxide generated within the phagosomes of neutrophils since bioluminescence results from a myeloperoxidase (MPO) mediated reaction. Luminol 0-7 myeloperoxidase Homo sapiens 132-147 23978851-6 2013 Luminol specifically reacts with the superoxide generated within the phagosomes of neutrophils since bioluminescence results from a myeloperoxidase (MPO) mediated reaction. Luminol 0-7 myeloperoxidase Homo sapiens 149-152 23890607-0 2013 A homogeneous hemin/G-quadruplex DNAzyme based turn-on chemiluminescence aptasensor for interferon-gamma detection via in-situ assembly of luminol functionalized gold nanoparticles, deoxyribonucleic acid, interferon-gamma and hemin. Luminol 139-146 interferon gamma Homo sapiens 88-104 23890607-1 2013 A homogeneous hemin/G-quadruplex DNAzyme (HGDNAzyme) based turn-on chemiluminescence aptasensor for interferon-gamma (IFN-gamma) detection is developed, via dynamic in-situ assembly of luminol functionalized gold nanoparticles (lum-AuNPs), DNA, IFN-gamma and hemin. Luminol 185-192 interferon gamma Homo sapiens 100-116 23890607-1 2013 A homogeneous hemin/G-quadruplex DNAzyme (HGDNAzyme) based turn-on chemiluminescence aptasensor for interferon-gamma (IFN-gamma) detection is developed, via dynamic in-situ assembly of luminol functionalized gold nanoparticles (lum-AuNPs), DNA, IFN-gamma and hemin. Luminol 185-192 interferon gamma Homo sapiens 118-127 23726881-7 2013 The generation of reactive oxygen species (ROS) and the activities of superoxide dismutase (SOD) and catalase (CAT) in the retinal tissues were determined by lucigenin- and luminol-enhanced chemiluminescence and enzyme-linked immunosorbent assay (ELISA). Luminol 173-180 catalase Rattus norvegicus 101-109 24455888-3 2013 Inhibitor of myeloperoxidase--4-aminobenzoic acid hydrazide, without any effect on lucigenin-dependent chemiluminescence of neutrophils stimulated with PMA, effectively suppressed luminol-dependent chemiluminescence (IC50 = 20 microM) under the same conditions. Luminol 180-187 myeloperoxidase Homo sapiens 13-28 24455888-4 2013 The transfer of the cells from medium with HSA-Cl and myeloperoxidase to fresh medium abolished an increase in PMA-induced luminol-dependent chemiluminescence, but not the ability of neutrophils to respond to re-addition of HSA-Cl. Luminol 123-130 myeloperoxidase Homo sapiens 54-69 24455888-7 2013 A significant positive correlation was found between myeloperoxidase activity in blood plasma of children with severe burns and the enhancing effects of albumin fraction of the same plasma on luminol-dependent chemiluminescence of PMA-stimulated donor neutrophils. Luminol 192-199 myeloperoxidase Homo sapiens 53-68 23994743-6 2013 Oxidation of the hydroxylated coumarins by the neutrophil myeloperoxidase produced highly reactive coumarin radical intermediates, which mediated the prooxidant effect observed in the luminol-enhanced chemiluminescence assay. Luminol 184-191 myeloperoxidase Homo sapiens 58-73 24077442-4 2013 In this study, we demonstrate that administration of luminol to mice that have been transplanted with 4T1 mammary tumor cells permits the detection of myeloperoxidase activity, and consequently, the location of the tumor. Luminol 53-60 myeloperoxidase Mus musculus 151-166 23770511-5 2013 The binding ability of luminol to the studied proteins followed the pattern: myoglobin>aldolase>ferritin>ovalbumin>catalase>ribonuclease>lysozyme>BSA>chymotrypsinoge. Luminol 23-30 catalase Homo sapiens 127-135 23708630-1 2013 An ultrasensitive electrochemiluminescence (ECL) immunosensor was constructed for ultrasensitive detection of carcinoembryonic antigen (CEA) based on an amplified cathodic ECL of luminol at low potential. Luminol 179-186 CEA cell adhesion molecule 3 Homo sapiens 110-134 23708630-1 2013 An ultrasensitive electrochemiluminescence (ECL) immunosensor was constructed for ultrasensitive detection of carcinoembryonic antigen (CEA) based on an amplified cathodic ECL of luminol at low potential. Luminol 179-186 CEA cell adhesion molecule 3 Homo sapiens 136-139 23726099-1 2013 In the present study, a novel and ultrasensitive electrochemiluminescence (ECL) immunosensor based on luminol cathodic ECL was fabricated by using Au nanoparticles and Pt nanoparticles (nano-AuPt) electrodeposited on graphene-carbon nanotubes nanocomposite as platform for the detection of carcinoembryonic antigen (CEA). Luminol 102-109 CEA cell adhesion molecule 3 Homo sapiens 316-319 23053451-0 2013 Chemiluminescence microfluidic system of gold nanoparticles enhanced luminol-silver nitrate for the determination of vitamin B12. Luminol 69-76 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 125-128 23318789-5 2013 When macrophages were activated in the presence of AANO2, a significant inhibition of NOX2 activity was observed as evaluated by cytochrome c reduction, luminol chemiluminescence, Amplex red fluorescence, and flow cytometry; this process also occurs under physiological mimic conditions within the phagosomes. Luminol 153-160 cytochrome b-245, beta polypeptide Mus musculus 86-90 22715144-4 2013 Based on the observed phenomenon, it was possible to determine Co(II), Fe(II) and Cr(III) ions with enhanced sensitivity and selectivity using the chelating reagents of the luminol-H2 O2 system. Luminol 173-180 mitochondrially encoded cytochrome c oxidase II Homo sapiens 63-69 22715144-0 2013 A chelate complex-enhanced luminol system for selective determination of Co(II), Fe(II) and Cr(III). Luminol 27-34 mitochondrially encoded cytochrome c oxidase II Homo sapiens 73-79 22715144-1 2013 A determination method for Co(II), Fe(II) and Cr(III) ions by luminol-H2 O2 system using chelating reagents is presented. Luminol 62-69 mitochondrially encoded cytochrome c oxidase II Homo sapiens 27-33 22715144-2 2013 A metal ion-chelating ligand complex with a Co(II) ion and a chelating reagent like ethylenediaminetetraacetic acid (EDTA) produced highly enhanced chemiluminescence (CL) intensity as well as longer lifetime in the luminol-H2 O2 system compared to metals that exist as free ions. Luminol 215-222 mitochondrially encoded cytochrome c oxidase II Homo sapiens 44-50 23478332-2 2013 Cytochrome c was digested by a protease, and heme was released as a peptide-heme conjugate, which greatly enhanced the luminol-H2O2 CL reaction. Luminol 119-126 cytochrome c, somatic Homo sapiens 0-12 23455711-1 2013 A previous study reported the use of luminol for the detection of myeloperoxidase (MPO) activity using optical imaging in infiltrating neutrophils under inflammatory disease conditions. Luminol 37-44 myeloperoxidase Mus musculus 66-81 23455711-1 2013 A previous study reported the use of luminol for the detection of myeloperoxidase (MPO) activity using optical imaging in infiltrating neutrophils under inflammatory disease conditions. Luminol 37-44 myeloperoxidase Mus musculus 83-86 23455711-2 2013 The detection is based on a photon-emitting reaction between luminol and an MPO metabolite. Luminol 61-68 myeloperoxidase Mus musculus 76-79 23455711-4 2013 In this study we report a chemiluminescence resonance energy transfer (CRET) methodology in which luminol-generated blue light excites nanoparticles to emit light in the near-infrared spectral range, resulting in remarkable improvement of MPO detectability in vivo. Luminol 98-105 myeloperoxidase Mus musculus 239-242 23455711-5 2013 CRET caused a 37-fold increase in luminescence emission over luminol alone in detecting MPO activity in lung tissues after lipopolysaccharide challenge. Luminol 61-68 myeloperoxidase Mus musculus 88-91 23053451-1 2013 A rapid and sensitive chemiluminescence (CL) system coupled with a microfluidic chip has been presented to determine vitamin B12 (VB12) based on the reaction of luminol and silver nitrate (AgNO(3)) in the presence of gold nanoparticles (AuNPs). Luminol 161-168 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 125-128 23162809-0 2013 Dual-channel cathodic electrochemiluminescence of luminol induced by injection of hot electrons on a niobate semiconductor modified electrode. Luminol 50-57 alcohol dehydrogenase iron containing 1 Homo sapiens 82-85 22917918-0 2013 A label-free electrochemiluminescence aptasensor for thrombin based on novel assembly strategy of oligonucleotide and luminol functionalized gold nanoparticles. Luminol 118-125 coagulation factor II, thrombin Homo sapiens 53-61 22917918-1 2013 In the work, a label-free electrochemiluminescence (ECL) aptasensor for the sensitive and selective detection of thrombin was constructed based on target-induced direct ECL signal change by virtue of a novel assembly strategy of oligonucleotide and luminol functionalized gold nanoparticles (luminol-AuNPs). Luminol 249-256 coagulation factor II, thrombin Homo sapiens 113-121 22917918-1 2013 In the work, a label-free electrochemiluminescence (ECL) aptasensor for the sensitive and selective detection of thrombin was constructed based on target-induced direct ECL signal change by virtue of a novel assembly strategy of oligonucleotide and luminol functionalized gold nanoparticles (luminol-AuNPs). Luminol 292-299 coagulation factor II, thrombin Homo sapiens 113-121 22917918-4 2013 Then luminol-AuNPs co-loaded with thiolated DNA capture probe 2 and thiolated thrombin binding aptamer (TBA) (luminol-AuNPs-probe 2/TBA) were assembled onto AuNPs-probe 1 modified electrode through the hybridization between capture probes 1 and 2. Luminol 110-117 coagulation factor II, thrombin Homo sapiens 78-86 22917918-7 2013 In the presence of target thrombin, TBA on the luminol-AuNPs could capture the thrombin onto the electrode surface, which produced a barrier for electro-transfer and influenced the electro-oxidation reaction of luminol, leading to a decrease in ECL intensity. Luminol 47-54 coagulation factor II, thrombin Homo sapiens 26-34 22917918-7 2013 In the presence of target thrombin, TBA on the luminol-AuNPs could capture the thrombin onto the electrode surface, which produced a barrier for electro-transfer and influenced the electro-oxidation reaction of luminol, leading to a decrease in ECL intensity. Luminol 47-54 coagulation factor II, thrombin Homo sapiens 79-87 22917918-7 2013 In the presence of target thrombin, TBA on the luminol-AuNPs could capture the thrombin onto the electrode surface, which produced a barrier for electro-transfer and influenced the electro-oxidation reaction of luminol, leading to a decrease in ECL intensity. Luminol 211-218 coagulation factor II, thrombin Homo sapiens 26-34 22917918-7 2013 In the presence of target thrombin, TBA on the luminol-AuNPs could capture the thrombin onto the electrode surface, which produced a barrier for electro-transfer and influenced the electro-oxidation reaction of luminol, leading to a decrease in ECL intensity. Luminol 211-218 coagulation factor II, thrombin Homo sapiens 79-87 22999887-3 2012 Systemic delivery of luminol (5-amino-2,3-dihydro-1,4-phthalazinedione) enables detection of acute inflammation largely mediated by tissue-infiltrating neutrophils, whose myeloperoxidase (MPO) activity is required for luminol bioluminescence. Luminol 21-28 myeloperoxidase Mus musculus 171-186 23101695-3 2012 After the competitive binding, the residual RhB-GA3 on the MIP was electro-oxidized to produce RhB oxide, which could greatly amplify the weak electrochemiluminescence (ECL) signal of luminol. Luminol 184-191 succinyl-CoA:glutarate-CoA transferase Homo sapiens 44-51 22392616-0 2013 Fast simultaneous determination of traces of Cu(II) and Co(II) in soils and sediments with the luminol/perborate chemiluminescent system. Luminol 95-102 mitochondrially encoded cytochrome c oxidase II Homo sapiens 56-62 22999887-3 2012 Systemic delivery of luminol (5-amino-2,3-dihydro-1,4-phthalazinedione) enables detection of acute inflammation largely mediated by tissue-infiltrating neutrophils, whose myeloperoxidase (MPO) activity is required for luminol bioluminescence. Luminol 21-28 myeloperoxidase Mus musculus 188-191 22999887-3 2012 Systemic delivery of luminol (5-amino-2,3-dihydro-1,4-phthalazinedione) enables detection of acute inflammation largely mediated by tissue-infiltrating neutrophils, whose myeloperoxidase (MPO) activity is required for luminol bioluminescence. Luminol 30-70 myeloperoxidase Mus musculus 171-186 22999887-3 2012 Systemic delivery of luminol (5-amino-2,3-dihydro-1,4-phthalazinedione) enables detection of acute inflammation largely mediated by tissue-infiltrating neutrophils, whose myeloperoxidase (MPO) activity is required for luminol bioluminescence. Luminol 30-70 myeloperoxidase Mus musculus 188-191 22575975-2 2012 METHODS: Initially, the crude water and methanol extracts were probed for their capacity to trigger immune cells" NADPH oxidase and MPO-dependent activities as measured by lucigenin- and luminol-amplified chemiluminescence, respectively; as compared to receptor-dependent (serum opsonised zymosan- OPZ) or receptor-independent phorbol myristerate acetate (PMA). Luminol 187-194 myeloperoxidase Homo sapiens 132-135 22911714-6 2012 Luminol-amplified chemiluminescence (LAC) was used to measure the rapid (10 min) and transient TNF-alpha induced increase in ROS production (168+-15%). Luminol 0-7 tumor necrosis factor Homo sapiens 95-104 22417160-3 2012 We designed a graphene-based CRET platform for homogeneous immunoassay of C-reactive protein (CRP), a key marker for human inflammation and cardiovascular diseases, using a luminol/hydrogen peroxide chemiluminescence (CL) reaction catalyzed by horseradish peroxidase. Luminol 173-180 C-reactive protein Homo sapiens 94-97 21641423-4 2011 Under the optimal conditions for luminol-O(2) system, the ECL signal intensity of luminol was linear with the concentration of dissolved oxygen in the range between 0.08 and 0.94 mM (r=0.9996) and for luminol-H(2)O(2) system, the ECL signal intensity of luminol was linear with the concentration of glucose in the range between 0.1 and 1000 muM (r=0.9998). Luminol 33-40 latexin Homo sapiens 341-344 22645466-1 2012 The present work deals with an attempt to study the effect of human and bovine serum albumin on kinetic parameters of chemiluminescence of luminol-hydrogen peroxide system catalyzed by manganese tetrasulfonatophenyl porphyrin (MnTSPP). Luminol 139-146 albumin Homo sapiens 79-92 21866963-3 2011 The conjugation of the antithrombin or anti-ATP aptamers to CdSe/ZnS semiconductor quantum dots (QDs) allowed the detection of thrombin or ATP through the luminescence of the QDs that is powered by a chemiluminescence resonance energy-transfer (CRET) process stimulated by the hemin/G-quadruplex/thrombin complex or the hemin/G-quadruplex/ATP nanostructure, in the presence of luminol/H(2)O(2). Luminol 377-384 serpin family C member 1 Homo sapiens 23-35 21866963-3 2011 The conjugation of the antithrombin or anti-ATP aptamers to CdSe/ZnS semiconductor quantum dots (QDs) allowed the detection of thrombin or ATP through the luminescence of the QDs that is powered by a chemiluminescence resonance energy-transfer (CRET) process stimulated by the hemin/G-quadruplex/thrombin complex or the hemin/G-quadruplex/ATP nanostructure, in the presence of luminol/H(2)O(2). Luminol 377-384 coagulation factor II, thrombin Homo sapiens 27-35 21866963-3 2011 The conjugation of the antithrombin or anti-ATP aptamers to CdSe/ZnS semiconductor quantum dots (QDs) allowed the detection of thrombin or ATP through the luminescence of the QDs that is powered by a chemiluminescence resonance energy-transfer (CRET) process stimulated by the hemin/G-quadruplex/thrombin complex or the hemin/G-quadruplex/ATP nanostructure, in the presence of luminol/H(2)O(2). Luminol 377-384 coagulation factor II, thrombin Homo sapiens 127-135 21807203-2 2011 The method exploited the Co(II)-catalysed CL reaction of luminol with hydrogen peroxide in alkaline medium. Luminol 57-64 mitochondrially encoded cytochrome c oxidase II Homo sapiens 25-30 22165010-0 2011 Subnanogram determination of aniracetam in pharmaceutical preparations and biofluids by flow injection analysis with chemiluminescence detection based on its enhancement of the myoglobin-luminol reaction. Luminol 187-194 myoglobin Homo sapiens 177-186 22165010-1 2011 A novel flow injection chemiluminescence method with a myoglobin-luminol system is described for determining aniracetam. Luminol 65-72 myoglobin Homo sapiens 55-64 22165010-2 2011 Myoglobin-bound aniracetam produced a complex that catalyzed the chemiluminescence reaction between luminol and myoglobin, leading to fast chemiluminescence. Luminol 100-107 myoglobin Homo sapiens 0-9 22165010-2 2011 Myoglobin-bound aniracetam produced a complex that catalyzed the chemiluminescence reaction between luminol and myoglobin, leading to fast chemiluminescence. Luminol 100-107 myoglobin Homo sapiens 112-121 21706074-1 2011 An immunosensor based on the electrochemiluminescence (ECL) of luminol was proposed by coupling enzymatic reaction to in situ generate coreactant with Pd nanoparticles as catalyst for the ECL reaction, which was successfully applied for the ultrasensitive detection of alpha-1-fetoprotein with a low detection limit of 33 fg mL(-1). Luminol 63-70 alpha fetoprotein Homo sapiens 269-288 21641423-4 2011 Under the optimal conditions for luminol-O(2) system, the ECL signal intensity of luminol was linear with the concentration of dissolved oxygen in the range between 0.08 and 0.94 mM (r=0.9996) and for luminol-H(2)O(2) system, the ECL signal intensity of luminol was linear with the concentration of glucose in the range between 0.1 and 1000 muM (r=0.9998). Luminol 82-89 latexin Homo sapiens 341-344 20821809-5 2011 The detection was based on the catalytic effect of Co(II) on the luminol chemiluminescence using perborate or percarbonate as oxidants. Luminol 65-72 mitochondrially encoded cytochrome c oxidase II Homo sapiens 51-57 21513282-6 2011 The gold nanorods were not only used as carriers of secondary antibody (Ab(2)) and GOx but also catalyzed the ECL reaction of luminol, which further amplified the ECL signal of luminol in the presence of glucose and oxygen. Luminol 126-133 hydroxyacid oxidase 1 Homo sapiens 83-86 21513282-6 2011 The gold nanorods were not only used as carriers of secondary antibody (Ab(2)) and GOx but also catalyzed the ECL reaction of luminol, which further amplified the ECL signal of luminol in the presence of glucose and oxygen. Luminol 177-184 hydroxyacid oxidase 1 Homo sapiens 83-86 21237316-5 2011 The sandwich-type immunoreactions between the AFP (antigen) and the two different antibodies bridged the donors (luminol) and acceptors (AuNPs), which led to the occurrence of CRET from luminol to AuNPs upon chemiluminescent reaction. Luminol 113-120 alpha fetoprotein Homo sapiens 46-49 21237316-5 2011 The sandwich-type immunoreactions between the AFP (antigen) and the two different antibodies bridged the donors (luminol) and acceptors (AuNPs), which led to the occurrence of CRET from luminol to AuNPs upon chemiluminescent reaction. Luminol 186-193 alpha fetoprotein Homo sapiens 46-49 21076754-1 2011 Polyacrylic acid coated nanoceria (PNCs) were found to greatly enhance the chemiluminescence (CL) intensity of the luminol-H(2)O(2) system, and by virtue of the catalytic ability of PNCs, a sensitive and specific sandwich assay for human alpha-thrombin was developed. Luminol 115-122 coagulation factor II, thrombin Homo sapiens 244-252 21318873-4 2011 Specifically, H(2)O(2) production by SMO is coupled to chemiluminescence generated by the horseradish peroxidase-catalyzed oxidation of luminol. Luminol 136-143 spermine oxidase Homo sapiens 37-40 21513282-4 2011 On the basis of the cathodic ECL signal of luminol on the graphene-modified electrode, an ECL sandwich immunosensor for sensitive detection of cancer biomarkers at low potential was developed with a multiple signal amplification strategy from functionalized graphene and gold nanorods multilabeled with glucose oxidase (GOx) and secondary antibody (Ab(2)). Luminol 43-50 hydroxyacid oxidase 1 Homo sapiens 303-318 21513282-4 2011 On the basis of the cathodic ECL signal of luminol on the graphene-modified electrode, an ECL sandwich immunosensor for sensitive detection of cancer biomarkers at low potential was developed with a multiple signal amplification strategy from functionalized graphene and gold nanorods multilabeled with glucose oxidase (GOx) and secondary antibody (Ab(2)). Luminol 43-50 hydroxyacid oxidase 1 Homo sapiens 320-323 21482278-1 2011 A novel, quantitative analytical method for measuring C-reactive protein (CRP) levels in human serum has been developed based on the catalytic activity of gold nanoparticles (GNPs) and luminol-H(2)O(2) chemiluminescence (CL). Luminol 185-192 C-reactive protein Homo sapiens 54-72 21482278-1 2011 A novel, quantitative analytical method for measuring C-reactive protein (CRP) levels in human serum has been developed based on the catalytic activity of gold nanoparticles (GNPs) and luminol-H(2)O(2) chemiluminescence (CL). Luminol 185-192 C-reactive protein Homo sapiens 74-77 19898718-6 2009 The activated CREB was visualized with a luminol-enhanced chemoluminescence detection system and evaluated by laser densitometry. Luminol 41-48 cAMP responsive element binding protein 1 Homo sapiens 14-18 20736176-3 2010 Six hours after an intraplantar injection of zymosan, Cot/tpl2(-/-) mice showed a 47% reduction in myeloperoxidase activity, concomitant with a 46% lower neutrophil recruitment and a 40% decreased luminol-mediated bioluminescence imaging in vivo. Luminol 197-204 mitogen-activated protein kinase kinase kinase 8 Mus musculus 54-57 20736176-4 2010 Accordingly, Cot/tpl2 deficiency provoked a 25-30% reduction in luminol-mediated bioluminescence and neutrophil recruitment together with a 65% lower macrophage recruitment 4 h following zymosan-induced peritonitis. Luminol 64-71 mitogen-activated protein kinase kinase kinase 8 Mus musculus 13-21 20095579-8 2010 In the presence of K(+), PS2.M (with hemin as a cofactor) exhibits a superior DNAzyme activity and effectively catalyzes the H(2)O(2)-mediated oxidation of 2,2"-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) or luminol, which results in a color change or generates CL emission. Luminol 237-244 taste 2 receptor member 64 pseudogene Homo sapiens 25-28 20095579-10 2010 This allows us to utilize PS2.M for quantitative analysis of aqueous Pb(2+) using the ABTS-H(2)O(2) colorimetric system and luminol-H(2)O(2) CL system. Luminol 124-131 taste 2 receptor member 64 pseudogene Homo sapiens 26-29 19347266-1 2010 It was found that the complex of cytochrome c (Cyt c) and hydrogen peroxide could significantly catalyze the chemiluminescence (CL) reaction from luminol-hydrogen peroxide, and a sensitive, rapid, and simple CL procedure was proposed for the determination of Cyt c in a flow injection system for the first time. Luminol 146-153 cytochrome c, somatic Homo sapiens 33-45 19347266-1 2010 It was found that the complex of cytochrome c (Cyt c) and hydrogen peroxide could significantly catalyze the chemiluminescence (CL) reaction from luminol-hydrogen peroxide, and a sensitive, rapid, and simple CL procedure was proposed for the determination of Cyt c in a flow injection system for the first time. Luminol 146-153 cytochrome c, somatic Homo sapiens 47-52 19347266-1 2010 It was found that the complex of cytochrome c (Cyt c) and hydrogen peroxide could significantly catalyze the chemiluminescence (CL) reaction from luminol-hydrogen peroxide, and a sensitive, rapid, and simple CL procedure was proposed for the determination of Cyt c in a flow injection system for the first time. Luminol 146-153 cytochrome c, somatic Homo sapiens 259-264 19743525-0 2010 Sensitive determination of gentiopicroside in medicine and bio-fluids using luminol-myoglobin chemiluminescence combined with flow injection technique. Luminol 76-83 myoglobin Homo sapiens 84-93 19743525-1 2010 A novel chemiluminescence method for the determination of gentiopicroside is presented, which was based on the inhibitory effect of gentiopicroside on the chemiluminescence reaction between luminol and myoglobin in a flow-injection system. Luminol 190-197 myoglobin Homo sapiens 202-211 20207043-3 2010 METHODS: Neutrophils were stimulated, in the absence or presence of plasma, with the chemotactic peptide fMLP (formyl-methionyl-leucyl-phenylalanine), and the ROS production was determined with luminol-enhanced chemiluminescence. Luminol 194-201 formyl peptide receptor 1 Homo sapiens 105-109 20446806-1 2010 A preliminary investigation was conducted into the influence of aspirin on the luminol-enhanced chemiluminescence of platelets stimulated with platelet-activating factor (PAF). Luminol 79-86 PCNA clamp associated factor Homo sapiens 143-169 20446806-1 2010 A preliminary investigation was conducted into the influence of aspirin on the luminol-enhanced chemiluminescence of platelets stimulated with platelet-activating factor (PAF). Luminol 79-86 PCNA clamp associated factor Homo sapiens 171-174 20446806-4 2010 Luminol-enhanced luminescence of platelet-rich plasma samples mixed with a PAF solution was measured. Luminol 0-7 PCNA clamp associated factor Homo sapiens 75-78 19305414-2 2009 Here we show that upon systemic administration, the small molecule luminol enables noninvasive bioluminescence imaging (BLI) of MPO activity in vivo. Luminol 67-74 myeloperoxidase Mus musculus 128-131 19666846-2 2009 BPA organ cultured for 24 h with 0.1 mM cobalt chloride (CoCl(2)) to increase the expression and activity of heme oxygenase-1 (HO-1) is accompanied by a decrease in 5 microM lucigenin-detectable superoxide and an increase in horseradish peroxidase-luminol detectable peroxide levels. Luminol 248-255 heme oxygenase 1 Bos taurus 109-125 19666846-2 2009 BPA organ cultured for 24 h with 0.1 mM cobalt chloride (CoCl(2)) to increase the expression and activity of heme oxygenase-1 (HO-1) is accompanied by a decrease in 5 microM lucigenin-detectable superoxide and an increase in horseradish peroxidase-luminol detectable peroxide levels. Luminol 248-255 heme oxygenase 1 Bos taurus 127-131 19334785-2 2009 It was found that the mixed solutions of melamine and myoglobin could react to form a complex on line, which could greatly inhibit the chemiluminescence intensity generated from the reaction between luminol and myoglobin. Luminol 199-206 myoglobin Homo sapiens 54-63 19334785-2 2009 It was found that the mixed solutions of melamine and myoglobin could react to form a complex on line, which could greatly inhibit the chemiluminescence intensity generated from the reaction between luminol and myoglobin. Luminol 199-206 myoglobin Homo sapiens 211-220 19334785-6 2009 The possible mechanism of luminol-myoglobin-melamine reaction is given. Luminol 26-33 myoglobin Homo sapiens 34-43 19441829-4 2009 Hydrogen peroxide, which was locally generated by the glucose oxidase (GOx)-catalyzed reaction, reacted with oxidized luminol which was simultaneously electrochemically generated at the positioned SECM electrode tip. Luminol 118-125 hydroxyacid oxidase 1 Homo sapiens 54-69 19441829-4 2009 Hydrogen peroxide, which was locally generated by the glucose oxidase (GOx)-catalyzed reaction, reacted with oxidized luminol which was simultaneously electrochemically generated at the positioned SECM electrode tip. Luminol 118-125 hydroxyacid oxidase 1 Homo sapiens 71-74 19186189-0 2009 The drug monosodium luminol (GVT) preserves crypt-villus epithelial organization and allows survival of intestinal T cells in mice infected with the ts1 retrovirus. Luminol 20-27 Trichinella spiralis resistance 1 Mus musculus 149-152 19364325-3 2009 Peroxidase activity of the complex of cytochrome c with dioleyl cardiolipin estimated by chemiluminescence with luminol decreased by 50% with quercetin, taxifolin, rutin, Trolox, and ionol at concentrations 0.7, 0.7, 0.8, 3, and 10 microM, respectively. Luminol 112-119 cytochrome c, somatic Homo sapiens 38-50 18055556-8 2007 Leukocytes isolated from lungs of MIF(-/-) mice were less activated, as assessed by their response to zymosan in a luminol-enhanced chemiluminescence assay. Luminol 115-122 macrophage migration inhibitory factor (glycosylation-inhibiting factor) Mus musculus 34-37 18316174-2 2008 Luminol-dependent CL activity, which reflects the production of reactive oxygen species (ROS) from PMNs, was up-regulated to approximately 150% when PMNs were treated with 0.05 ng/ml of AFB1 upon stimulation with N-formyl-methionine-leucine-phenylalanine (fMLP) or zymosan. Luminol 0-7 formyl peptide receptor 1 Homo sapiens 256-260 19173042-5 2009 The free HRP-anti-AFP was trapped by the immobilized antigen in the column and detected via chemiluminescence due to its sensitive effect on the reaction of luminol and hydrogen peroxide. Luminol 157-164 alpha fetoprotein Homo sapiens 18-21 18335473-4 2008 After the non-competitive immunoreaction, the free HRP-labeled CA15-3 antibody (Ab*) and the bound Ab*-antigen (Ab*-Ag) complex were separated in a separation capillary and then catalyzed the CL reaction of luminol and H(2)O(2 )in a reaction capillary following the separation capillary. Luminol 207-214 mucin 1, cell surface associated Homo sapiens 63-69 18006077-10 2008 The CL response obtained with TNF-alpha was maximal after 5 min and more pronounced with luminol than with lucigenin. Luminol 89-96 tumor necrosis factor Equus caballus 30-39 18006077-11 2008 With IL-1beta, the luminol-enhanced CL response of neutrophils was short-lived and inversely proportional to the cytokine concentration: the CL response returned to baseline after 12 min, and became even lower than the baseline value for 10 and 100 ng IL-1beta. Luminol 19-26 interleukin-1 beta Equus caballus 5-13 18006077-11 2008 With IL-1beta, the luminol-enhanced CL response of neutrophils was short-lived and inversely proportional to the cytokine concentration: the CL response returned to baseline after 12 min, and became even lower than the baseline value for 10 and 100 ng IL-1beta. Luminol 19-26 interleukin-1 beta Equus caballus 252-260 31627696-3 2007 In the follicular phase of a menstrual cycle, leptin suppressed phagocytic activity when used in a low dose (10 ng/ ml) and reduced the monocytic production of active oxygen forms when used in the high dose in the induced luminol-dependent chemiluminescence (LDC). Luminol 222-229 leptin Homo sapiens 46-52 17998749-0 2007 Post-chemiluminescence phenomenon of NBS-luminol reactions and their applications to flow injection analysis of piroxicam. Luminol 41-48 nibrin Homo sapiens 37-40 17992648-5 2007 Exhaled H2O2 was determined fluorometrically and resting and n-formyl-methionyl-leucyl-phenylalanine (fMLP) luminol-dependent whole blood chemiluminescence (LBCL) were measured simultaneously. Luminol 108-115 formyl peptide receptor 1 Homo sapiens 102-106 16878866-5 2006 Moreover, with the presence of Co(II) (1.0 x 10(-4) mol/L) in the mobile phase, the linear range of the concentration for luminol was 2.0 x 10(-9)-2.0 x 10(-6) mol/L with a detection limit (S/N = 3) of 2.0 x 10(-10) mol/L, and 2.5 x 10(4) theoretical plates was achieved. Luminol 122-129 mitochondrially encoded cytochrome c oxidase II Homo sapiens 31-37 17342537-1 2007 A carbon nanotube paste (CNTP) electrode and a carbon nanotube paste/glucose oxidase (CNTP/GOx) electrode were prepared, and the electrochemiluminescent (ECL) behavior of luminol in the presence of glucose was investigated in detail at each of these electrodes. Luminol 171-178 hydroxyacid oxidase 1 Homo sapiens 86-94 17397653-0 2007 On-line selective detection of antioxidants free-radical scavenging activity based on Co(II)/EDTA-induced luminol chemiluminescence by flow injection analysis. Luminol 106-113 mitochondrially encoded cytochrome c oxidase II Homo sapiens 86-92 17397653-1 2007 This study establishes a new method to analyze the radical scavenging activity of antioxidants based on the luminol-H(2)O(2)-Co(II)/EDTA chemiluminescence and flow injection analysis. Luminol 108-115 mitochondrially encoded cytochrome c oxidase II Homo sapiens 125-131 17268053-3 2007 The H2O2/luminol-dependent CL intensity in a system containing 3.7 nM catalase and low concentrations (10-100 nM) of green tea flavanols (epigallocatechin gallate; EGCG and epicatechin gallate; EG) was enhanced in comparison with that of a system without catalase, suggesting that EGCG and EG partially suppressed catalase activity. Luminol 9-16 catalase Homo sapiens 70-78 17268053-3 2007 The H2O2/luminol-dependent CL intensity in a system containing 3.7 nM catalase and low concentrations (10-100 nM) of green tea flavanols (epigallocatechin gallate; EGCG and epicatechin gallate; EG) was enhanced in comparison with that of a system without catalase, suggesting that EGCG and EG partially suppressed catalase activity. Luminol 9-16 catalase Homo sapiens 255-263 17268053-3 2007 The H2O2/luminol-dependent CL intensity in a system containing 3.7 nM catalase and low concentrations (10-100 nM) of green tea flavanols (epigallocatechin gallate; EGCG and epicatechin gallate; EG) was enhanced in comparison with that of a system without catalase, suggesting that EGCG and EG partially suppressed catalase activity. Luminol 9-16 catalase Homo sapiens 255-263 16765108-3 2006 After separation on a reversed-phase C18 column (runtime 20 min), aminoglycoside is detected on the basis of its complex formation reaction with Cu(II), the catalyst of the luminol/hydrogen peroxide chemiluminescence system. Luminol 173-180 Bardet-Biedl syndrome 9 Homo sapiens 37-40 16455289-2 2006 This method is based on the fact that both Co(II) and Cr(III) catalyze the luminol-H(2)O(2) CL reaction, and that their catalytic activities are significantly different on the same reaction condition. Luminol 75-82 mitochondrially encoded cytochrome c oxidase II Homo sapiens 43-49 17098412-3 2007 In the GOx/DNAzyme system, the GOx-mediated oxidation of glucose led to the formation of H(2)O(2), and this activated the oxidation of ABTS to a colored product, or to the generation of chemiluminescence in the presence of luminol. Luminol 223-230 hydroxyacid oxidase 1 Homo sapiens 7-10 17098412-3 2007 In the GOx/DNAzyme system, the GOx-mediated oxidation of glucose led to the formation of H(2)O(2), and this activated the oxidation of ABTS to a colored product, or to the generation of chemiluminescence in the presence of luminol. Luminol 223-230 hydroxyacid oxidase 1 Homo sapiens 31-34 17098412-4 2007 The MP-11/anti-thrombin aptamer enabled the amplified analysis of thrombin by the MP-11-mediated generation of chemiluminescence in the presence of luminol/H(2)O(2). Luminol 148-155 coagulation factor II, thrombin Homo sapiens 15-23 17098412-4 2007 The MP-11/anti-thrombin aptamer enabled the amplified analysis of thrombin by the MP-11-mediated generation of chemiluminescence in the presence of luminol/H(2)O(2). Luminol 148-155 coagulation factor II, thrombin Homo sapiens 66-74 17374957-6 2007 The effect of cAMP, H89 (inhibitor PKA), and PD169316 (inhibitor p38 MAPK) on ROS production was quantified in a luminol-dependent chemiluminescence assay (relative light units/min) and by InsP3 release (cpm). Luminol 113-120 mitogen-activated protein kinase 14 Homo sapiens 65-73 17007989-3 2006 We found an increased formation of ROS after 2-CPA exposure using three different methods; the fluorescent probe DCFH-DA and the chemiluminescent probes lucigenin and luminol. Luminol 167-174 carboxypeptidase A1 Homo sapiens 47-50 17159800-7 2006 The chemiluminescence signal, initiated by phorbol-12-myristate-13-acetate, was enhanced either with isoluminol (extracellular) or with luminol in the presence of extracellular scavengers, superoxide dismutase and catalase (intracellular). Luminol 104-111 catalase Homo sapiens 214-222 16125122-2 2005 The protease substrate derived from the Gag precursor protein of Mason-Pfizer monkey virus (M-PMV) was conjugated with horseradish peroxidase (HRP), which catalyzes oxidation of luminol in the assay. Luminol 178-185 Pr78 Mason-Pfizer monkey virus 40-43 16150638-0 2006 Inhibition of superoxide dismutase, Vitamin C and glutathione on chemiluminescence produced by luminol and the mixture of sulfite and bisulfite. Luminol 95-102 superoxide dismutase 1 Homo sapiens 14-34 16150638-3 2006 The observation that the CL intensities were inhibited by superoxide dismutase (SOD), Vitamin C (Vc) and glutathione (GSH) in a dose-dependent manner suggested that superoxide radical (O2*-) was involved in the CL reaction and responsible for oxidation of luminol. Luminol 256-263 superoxide dismutase 1 Homo sapiens 58-78 16150638-3 2006 The observation that the CL intensities were inhibited by superoxide dismutase (SOD), Vitamin C (Vc) and glutathione (GSH) in a dose-dependent manner suggested that superoxide radical (O2*-) was involved in the CL reaction and responsible for oxidation of luminol. Luminol 256-263 superoxide dismutase 1 Homo sapiens 80-83 16376177-6 2006 It could be in relation with (i) a synergistic effect upon fMLP receptor leading to an increase in H(2)O(2)/HOCl production or (ii) the generation of new oxydant products originating in cephalosporin lysis under HOCl attack, which would be able to react with luminol. Luminol 259-266 formyl peptide receptor 1 Homo sapiens 59-72 16889354-2 2006 According to the study, the level of chromosomal aberrations in peripheral blood lymphocytes shows a strong correlation with PON54 left allele and GSTM1 null genotype, and can be described by the polynomial function of blood plasma luminol-dependent chemiluminescence. Luminol 232-239 glutathione S-transferase mu 1 Homo sapiens 147-152 16439092-1 2006 A sensitive chemiluminescence method, based on the inhibitory effect of clindamycin on the chemiluminescence reaction between luminol and myoglobin in a flow-injection system, is proposed for the determination of clindamycin. Luminol 126-133 myoglobin Homo sapiens 138-147 16502478-1 2006 Luminol-amplified chemiluminescence (CL) from phagocytes has previously been shown to be almost completely dependent on the release of myeloperoxidase (MPO) from azurophilic granules. Luminol 0-7 myeloperoxidase Homo sapiens 135-150 16502478-1 2006 Luminol-amplified chemiluminescence (CL) from phagocytes has previously been shown to be almost completely dependent on the release of myeloperoxidase (MPO) from azurophilic granules. Luminol 0-7 myeloperoxidase Homo sapiens 152-155 17119274-1 2006 In this work the influence of H2O2 on the ability of human blood monocytes to generate ROS upon stimulation of cells by adhesion to glass surface and fMLP was studied using the luminol-dependent chemiluminescence (LDCL) method. Luminol 177-184 formyl peptide receptor 1 Homo sapiens 150-154 15998149-0 2005 Soybean peroxidase-catalyzed oxidation of luminol by hydrogen peroxide. Luminol 42-49 peroxidase Glycine max 8-18 15998149-1 2005 Anionic soybean peroxidase Glycine max (SbP) is shown to efficiently catalyze luminol oxidation by hydrogen peroxide. Luminol 78-85 peroxidase Glycine max 16-26 15998149-1 2005 Anionic soybean peroxidase Glycine max (SbP) is shown to efficiently catalyze luminol oxidation by hydrogen peroxide. Luminol 78-85 sucrose-binding protein 2 Glycine max 40-43 15998149-5 2005 The detection limit of SbP in the reaction of luminol oxidation is 0.3 x 10(-12) M. Therefore, high sensitivity in combination with the long-term chemiluminescent signal is indicative of good prospects for application of this enzyme in enzyme immunoassay with chemiluminescent detection. Luminol 46-53 sucrose-binding protein 2 Glycine max 23-26 16134227-0 2005 Post-chemiluminescence behaviour of Ni2+, Mg2+, Cd2+ and Zn2+ in the potassium ferricyanide-luminol reaction. Luminol 92-99 CD2 molecule Homo sapiens 48-51 16392333-4 2005 Luminol chemiluminescence recorded the whole pool of active oxygen and showed the summary activity of myeloperoxidase and NADPH-oxidase, while luceginin chemiluminescence measured formation of superoxide anion radical (*O(-)2) and evaluated the activity of NADPH-oxidase. Luminol 0-7 myeloperoxidase Homo sapiens 102-117 15924325-2 2005 The method is based on the chemiluminescence (CL) generated during the oxidation of luminol by N-bromosuccinimide (NBS) and N-chlorosuccinimide (NCS) in alkaline medium. Luminol 84-91 nibrin Homo sapiens 115-118 15570291-0 2004 p-Iodophenol-enhanced luminol chemiluminescent assay applied to discrimination between acute lymphoblastic and minimally differentiated acute myeloid (FAB-M0) or acute megakaryoblastic (FAB-M7) leukemias. Luminol 22-29 FA complementation group B Homo sapiens 151-154 15347370-7 2004 Oxidative metabolism was determined by a luminol-dependent chemiluminescence assay after activation with eotaxin or secretory IgA (sIgA). Luminol 41-48 C-C motif chemokine ligand 11 Homo sapiens 105-112 15378141-6 2004 The effect of various concentrations (1 to 200 microg/mL blood) of CRP on the generation of oxygen radicals by neutrophils was measured as luminol-dependent chemiluminescence (chemiluminescent activity) on a luminometer (Auto Lumat LB953, EG & G Berthold, Gaithersburg, MD). Luminol 139-146 C-reactive protein Homo sapiens 67-70 15056492-5 2004 Generation of reactive species by MPO/H(2)O(2) in Earl"s solution (pH=7.2) at 37 degrees C was investigated by monitoring of chemiluminescence using luminol as light emitter. Luminol 149-156 myeloperoxidase Homo sapiens 34-37 14663544-0 2004 A study of the chemiluminescence behavior of myoglobin with luminol and its analytical applications. Luminol 60-67 myoglobin Homo sapiens 45-54 14663544-1 2004 A chemiluminescence signal at 425 nm was observed when ferric state myoglobin was mixed with luminol in alkaline medium. Luminol 93-100 myoglobin Homo sapiens 68-77 15644248-0 2005 Flow injection determination of p-aminophenol at trace level using inhibited luminol-dimethylsulfoxide-NaOH-EDTA chemiluminescence. Luminol 77-84 poly(A) polymerase alpha Homo sapiens 32-45 15644248-1 2005 A novel flow injection procedure was developed for the determination of p-aminophenol (PAP) based on the inhibition by PAP of the chemiluminescence from luminol-dimethylsulfoxide (DMSO)-NaOH-EDTA system. Luminol 153-160 poly(A) polymerase alpha Homo sapiens 72-85 15644248-1 2005 A novel flow injection procedure was developed for the determination of p-aminophenol (PAP) based on the inhibition by PAP of the chemiluminescence from luminol-dimethylsulfoxide (DMSO)-NaOH-EDTA system. Luminol 153-160 poly(A) polymerase alpha Homo sapiens 87-90 15644248-1 2005 A novel flow injection procedure was developed for the determination of p-aminophenol (PAP) based on the inhibition by PAP of the chemiluminescence from luminol-dimethylsulfoxide (DMSO)-NaOH-EDTA system. Luminol 153-160 poly(A) polymerase alpha Homo sapiens 119-122 15555544-6 2004 COX-2 inhibitors inhibited in a dose-dependent manner the luminol-enhanced CL while ibuprofen and diclofenac increased the chemiluminescence response. Luminol 58-65 mitochondrially encoded cytochrome c oxidase II Homo sapiens 0-5 15476671-3 2004 In this study, we show that HT inhibits luminol-amplified chemiluminescence of human neutrophils stimulated with N-formyl-methionyl-leucyl-phenylalanine (fMLP), phorbol myristate acetate (PMA) and opsonized zymosan. Luminol 40-47 formyl peptide receptor 1 Homo sapiens 154-158 15570291-1 2004 INTRODUCTION: In this report, we propose the application of the p-iodophenol-enhanced luminol chemiluminescent technique to the determination of peroxidase (myeloperoxidase and/or platelet peroxidase) activity in blasts of minimally differentiated acute myeloblastic leukemia (AML-M0) and acute megakaryoblastic leukemia (AML-M7). Luminol 86-93 myeloperoxidase Homo sapiens 157-199 15123225-8 2004 Mean thiol concentration in EBC rose (p<0.05) after treatment with NAC and reached 1.03+/-0.48 microM at 3 h. Although, 25 and 50 mM NAC completely inhibited H(2)O(2)-peroxidase-luminol-dependent chemiluminescence, detectable amounts of H(2)O(2) were generated in NAC solutions. Luminol 181-188 X-linked Kx blood group Homo sapiens 136-139 15765929-4 2004 Respiratory burst was assessed by luminol-dependent chemoluminescence after stimulation with 10 microM n-formyl-met-leu-phe (FMLP). Luminol 34-41 formyl peptide receptor 1 Homo sapiens 125-129 15123225-8 2004 Mean thiol concentration in EBC rose (p<0.05) after treatment with NAC and reached 1.03+/-0.48 microM at 3 h. Although, 25 and 50 mM NAC completely inhibited H(2)O(2)-peroxidase-luminol-dependent chemiluminescence, detectable amounts of H(2)O(2) were generated in NAC solutions. Luminol 181-188 X-linked Kx blood group Homo sapiens 136-139 12675337-3 2003 Through water injection, luminol and periodate were eluted from the anion-exchange column to generate the chemiluminescence, which was inhibited in the presence of lysozyme. Luminol 25-32 lysozyme Homo sapiens 164-172 18969048-3 2003 Light emission was produced for the chemiluminescence reaction between luminol and hydrogen peroxide in buffer carbonate conditions (pH 10.8) catalysed by Cr(III), Co(II) and Cu(II). Luminol 71-78 mitochondrially encoded cytochrome c oxidase II Homo sapiens 164-170 12754093-7 2003 In the presence of neutrophils, the A1242-induced luminol chemiluminescence was decreased by the superoxide dismutase inhibitor diethyldithiocarbamic acid (DDC) and the myeloperoxidase inhibitor salicylhydroxamic acid (SHA). Luminol 50-57 myeloperoxidase Homo sapiens 169-184 12752326-4 2003 Oxidative metabolism was determined by a luminol-dependent chemiluminescence assay after activation with eotaxin or secretory immunoglobulin A (sIgA). Luminol 41-48 C-C motif chemokine ligand 11 Homo sapiens 105-112 12763136-10 2003 Epitope-specific anti-Siglec-5 monoclonal antibodies did not directly activate human neutrophils; however, antibody binding augmented neutrophil oxidative burst activity as determined by fMLP-induced luminol-dependent chemiluminescence. Luminol 200-207 sialic acid binding Ig like lectin 5 Homo sapiens 22-30 12763136-10 2003 Epitope-specific anti-Siglec-5 monoclonal antibodies did not directly activate human neutrophils; however, antibody binding augmented neutrophil oxidative burst activity as determined by fMLP-induced luminol-dependent chemiluminescence. Luminol 200-207 formyl peptide receptor 1 Homo sapiens 187-191 12653201-4 2003 Pro-oxidant activity in serum of beta-thal/Hb E was demonstrated by luminol-mediated chemiluminescence, a sensitive method for screening of free radical generation in vitro. Luminol 68-75 hemoglobin subunit epsilon 1 Homo sapiens 43-47 12630114-1 2003 The influence of oxidized fibrinogen on the intensity of luminol-dependent chemilumin escence of blood leukocytes, stimulated by opsonized zymosan was studied. Luminol 57-64 fibrinogen beta chain Homo sapiens 26-36 12569271-7 2003 Luminol-derived ROS generation was also significantly increased in the neutrophils isolated from the women with pre-eclampsia compared with the normotensive controls in the case of both agonists (fMLP: pre-eclamptic 1.955 +/- 0.316 RLU.s and normotensive 1.058 +/- 0.191 RLU.s, P = 0.023; PMA: pre-eclamptic 4.108 +/- 0.351 RLU.s and normotensive 3.073 +/- 0.332 RLU.s, P = 0.042). Luminol 0-7 formyl peptide receptor 1 Homo sapiens 196-200 12553769-8 2003 The ECL peak at 1.54 V was suggested to be due to the electrooxidation of OH- to HO2- at higher potential and then to O2-, which reacted with luminol to produce light emission. Luminol 142-149 heme oxygenase 2 Homo sapiens 81-84 12630114-2 2003 It was shown that the introduction of fibrinogen modified by UV-irradiation in to a suspension of cells resulted in a significant increase in the intensity of the luminol-dependent chemiluminescence of leukocytes. Luminol 163-170 fibrinogen beta chain Homo sapiens 38-48 12164363-2 2002 The ROS production by human neutrophils was monitored by luminol-amplified chemiluminescence after cell stimulation with the chemotactic tripeptide, fMLP, or with the phorbol ester, PMA. Luminol 57-64 formyl peptide receptor 1 Homo sapiens 149-153 11959481-3 2002 Dopamine is oxidized by oxygen under the catalysis of polyphenol oxidase in the tissue column to produce hydrogen peroxide, which can react with luminol in the presence of peroxidase of potato tissue to generate CL signal. Luminol 145-152 peroxidase N1 Solanum tuberosum 172-182 12033328-9 2002 The formation of *CO4- has very important analytical implications since this species appears to enhance or quench the CL signal from luminol and 1,10-phenanthroline, respectively. Luminol 133-140 complement C4A (Rodgers blood group) Homo sapiens 18-21 12434244-4 2002 The methods proposed in this paper are based on the transformation of all dissolved vanadium species in seawater into organic complexes by use of synthetic complexing agents such as dithizone, luminol, or 8-hydroxyquinoline; the resulting vanadium-organic complexes were sorbed on to a C(18) column at a flow rate of 5 mL min(-1). Luminol 193-200 CD59 molecule (CD59 blood group) Homo sapiens 322-328 12372906-4 2002 Michael adducts 1-4 inhibited the formation of reactive oxygen species in fMLP-stimulated human neutrophils as measured by luminol chemiluminescence. Luminol 123-130 formyl peptide receptor 1 Homo sapiens 74-78 12458630-4 2002 Both apoA-I and apoA-II exerted approximately 30% inhibition on the oxidative burst of neutrophils stimulated by opsonized zymosan, as revealed by the luminol-enhanced chemiluminescence assay. Luminol 151-158 apolipoprotein A1 Homo sapiens 5-11 12458630-4 2002 Both apoA-I and apoA-II exerted approximately 30% inhibition on the oxidative burst of neutrophils stimulated by opsonized zymosan, as revealed by the luminol-enhanced chemiluminescence assay. Luminol 151-158 apolipoprotein A2 Homo sapiens 16-23 12420057-1 2002 Fibrinogen intensified luminol-dependent chemiluminescence of blood leukocytes stimulated with opsonized zymosan. Luminol 23-30 fibrinogen beta chain Homo sapiens 0-10 12404881-4 2002 This study has been performed to investigate in vitro by means of luminol amplified chemiluminescence the ability of the concentration of 35 mumol/l NAC available after single oral administration of 1200 NAC to interfere with human neutrophil oxidative burst evoked by both corpuscolate and soluble stimulants, in comparison with 16 mumol/l NAC, the serum concentration obtainable after single oral administration of 600 mg NAC. Luminol 66-73 X-linked Kx blood group Homo sapiens 149-152 11922293-4 2002 The peak height of the first peak was due to the concentrations of urate and other reductants in the sample; the immobilized uricase was used to decompose urate, and the hydrogen peroxide produced was decomposed with a luminol-hydrogen peroxide reaction by immobilized peroxidase. Luminol 219-226 urate oxidase (pseudogene) Homo sapiens 125-132 11969156-6 2002 The rate constant for one stage of the conversion of luminol oxidation product is approximately 0.2 min-1, and the rate constant of the other is severalfold greater. Luminol 53-60 CD59 molecule (CD59 blood group) Homo sapiens 100-105 12038511-7 2002 Based on these data, it is concluded that hydrogen peroxide might be the source of hydroxyl radicals directly oxidizing luminol in the first phase of the LDCL signal, while in the second phase it serves as a substrate of myeloperoxidase in the peroxidation reaction of the luminol. Luminol 120-127 myeloperoxidase Rattus norvegicus 221-236 12038511-7 2002 Based on these data, it is concluded that hydrogen peroxide might be the source of hydroxyl radicals directly oxidizing luminol in the first phase of the LDCL signal, while in the second phase it serves as a substrate of myeloperoxidase in the peroxidation reaction of the luminol. Luminol 273-280 myeloperoxidase Rattus norvegicus 221-236 11855670-6 2002 SOD (100-300 U/ml), catalase (3000-6000 U/ml) or DPI (10-100 microM), concentration-dependently reduced luminol-enhanced chemiluminescence signal from the colonic mucosa, while allopurinol (10-100 microM), a xanthine oxidase inhibitor, did not affect the chemiluminescence signal. Luminol 104-111 superoxide dismutase [Mn], mitochondrial Cavia porcellus 0-3 11721898-1 2001 Using a heterogeneous catalyst, Co(II)-ethanolamine complex sorbed on Dowex-50W resin, the chemiluminescence (CL) of luminol in unbuffered or weakly acidic solution was studied in the presence of H2O2. Luminol 117-124 mitochondrially encoded cytochrome c oxidase II Homo sapiens 32-38 11813598-8 2001 Luminol-dependent chemiluminescence levels in groups GT were severely reduced, while the and luminol-dependent chemiluminescence levels in groups GRT, GPT, and GAT were almost the same as the levels in group G. The plasma interleukin-8 levels were higher in the transfused groups, and lower in groups GRT, GPT, and GAT. Luminol 93-100 glutamic--pyruvic transaminase Rattus norvegicus 151-154 11405886-0 2001 Long-term chemiluminescent signal is produced in the course of luminol peroxidation catalyzed by peroxidase isolated from leaves of african oil palm tree. Luminol 63-70 peroxidase N1 Nicotiana tabacum 97-107 11512144-1 2001 We studied the effect of carbon disulphide (CS2) on the generation of superoxide anion (O2-*) and its chemiluminescence (CL) in the pyrogallol-luminol system. Luminol 143-150 chorionic somatomammotropin hormone 2 Homo sapiens 44-47 11512144-7 2001 The results suggest that CS2 can induce the pyrogallol-luminol system to generate an increased amount of O2-* and delay the CL peak time. Luminol 55-62 chorionic somatomammotropin hormone 2 Homo sapiens 25-28 11708095-3 2001 The immobilized UC was employed to decompose urate, which is one of the major interfering components in serum for a luminol-H2O2 chemiluminescence reaction. Luminol 116-123 urate oxidase (pseudogene) Homo sapiens 16-18 11473436-3 2001 Radical scavenging activities of all compounds were determined by quantifying their effects on luminol-enhanced chemiluminescence in formyl-methionyl-leucyl-phenylalanine (FMLP) stimulated human polymorphonuclear neutrophils (PMNs). Luminol 95-102 formyl peptide receptor 1 Homo sapiens 172-176 11356619-9 2001 The 3-morpholinosydnominine (SIN-1) generation of peroxynitrite and its oxidative interaction with luminol to produce blue light during ischemia-reperfusion was also blocked by acetaminophen. Luminol 99-106 MAPK associated protein 1 Homo sapiens 29-34 11405886-1 2001 Optimal conditions were found for the oxidation of luminol by hydrogen peroxide in the presence of peroxidase isolated from leaves of the African oil palm tree Elaeis guineensis (AOPTP). Luminol 51-58 peroxidase N1 Nicotiana tabacum 99-109 11006316-4 2000 The luminol chemiluminescence measuring total ROS production of blood PMN stimulated by either a phorbol ester (PMA) or a chemoattractant peptide, formyl-Met-Leu-Phe (fMLP) was significantly inhibited by prostasomes. Luminol 4-11 formyl peptide receptor 1 Homo sapiens 147-165 11238274-8 2001 Luminol chemiluminescence, inhibitable by the peroxynitrite scavengers ebselen and uric acid, was markedly increased in apoE(-/-) aortic rings. Luminol 0-7 apolipoprotein E Mus musculus 120-124 11281625-2 2001 Co-incubation of purified PMNL with platelets that were activated with thrombin and then fixed and washed, resulted in the formation of platelet-PMNL conjugates as well as in a generation of reactive oxygen species that were measured as luminol-enhanced chemiluminescence. Luminol 237-244 coagulation factor II, thrombin Homo sapiens 71-79 11926296-9 2001 Although luminol is efficiently dioxygenated by a MPO-dependent mechanism in HPMNL, use of peroxidase-deficient CPMNLs indicates that this substrate does not exclusively measure peroxidase activity. Luminol 9-16 eosinophil peroxidase Gallus gallus 50-53 11409842-6 2000 Luminol amplified chemiluminescence of PMN leukocytes was increased in the order: thrombin<FMLP<A23187<PMA, but platelets alone did not show detectable chemiluminescence response to any stimulation. Luminol 0-7 coagulation factor II, thrombin Homo sapiens 82-90 11409842-6 2000 Luminol amplified chemiluminescence of PMN leukocytes was increased in the order: thrombin<FMLP<A23187<PMA, but platelets alone did not show detectable chemiluminescence response to any stimulation. Luminol 0-7 formyl peptide receptor 1 Homo sapiens 94-98 11035728-6 2000 We found that treatment of the phagocytes with porin inhibits the release of reactive oxygen species measured as luminol-enhanced chemiluminescence in response to zymosan, latex particles, and gonococci. Luminol 113-120 voltage dependent anion channel 1 Homo sapiens 47-52 11395328-0 2000 Evaluation of scavenging activity assessed by Co(II)/EDTA-induced luminol chemiluminescence and DPPH* (2,2-diphenyl-1-picrylhydrazyl) free radical assay. Luminol 66-73 mitochondrially encoded cytochrome c oxidase II Homo sapiens 46-52 11395328-1 2000 The scavenging activities of three standard antioxidants, quercetin, ascorbic acid, and trolox, were evaluated by Co(II)/ethylenediamine-tetraacetic acid (EDTA)-induced luminol chemiluminescence and the 2,2-diphenyl-1-picrylhydrazyl (DPPH*) free radical assay. Luminol 169-176 mitochondrially encoded cytochrome c oxidase II Homo sapiens 114-120 11395328-2 2000 Therefore, the aim of this study was to characterise an enzyme-free and time-independent chemiluminescence method for the assessment of the scavenging profile of compounds in a cell-free system using the Co(II)/EDTA-luminol-peroxide system. Luminol 216-223 mitochondrially encoded cytochrome c oxidase II Homo sapiens 204-210 11395328-3 2000 These results showed that the three standards were efficient and effective in inhibiting both Co(II)/EDTA-induced luminol chemiluminescence and the free radical DPPH*. Luminol 114-121 mitochondrially encoded cytochrome c oxidase II Homo sapiens 94-100 11395328-5 2000 The present study has applied a simple and precise procedure for the study of hydroxyl radical scavenging activity by Co(II)/EDTA-induced luminol chemiluminescence, and this was assessed by DPPH* free radical scavenging. Luminol 138-145 mitochondrially encoded cytochrome c oxidase II Homo sapiens 118-124 11006316-4 2000 The luminol chemiluminescence measuring total ROS production of blood PMN stimulated by either a phorbol ester (PMA) or a chemoattractant peptide, formyl-Met-Leu-Phe (fMLP) was significantly inhibited by prostasomes. Luminol 4-11 formyl peptide receptor 1 Homo sapiens 167-171 10591153-4 1999 Thus, we studied the mechanism of inhibition of neutrophil superoxide (O2*-) generation by pravastatin and found that pravastatin at 0.5 mM inhibited the receptor-mediated tyrosine kinase (TK)-dependent pathway of O2*- generation and also luminol chemiluminescence but not the protein kinase C (PKC)-dependent or the TK- and PKC-independent pathways of O2*- generation in neutrophils. Luminol 239-246 TXK tyrosine kinase Homo sapiens 172-187 11060899-10 2000 Our results show a significant decrease in the luminol- and lucigenin-amplified chemiluminescence of PAF stimulated PLT in the diabetic group with respect to controls. Luminol 47-54 PCNA clamp associated factor Homo sapiens 101-104 11094642-5 2000 In addition to these phenotypical changes, IL-4 primed the phorbol-12-myristate-13-acetate (PMA)-induced luminol-dependent chemiluminescence response (LDCL) by normal human monocytes; this priming effect was abrogated in the presence of Lyprinol, or of BW B70C. Luminol 105-112 interleukin 4 Homo sapiens 43-47 10781007-7 2000 N-2-mercaptopropionylglycine (MPG, 1 microM - 10 mM) produced a concentration-dependent inhibition of peroxynitrite signals in luminol chemiluminescence and 67+/-1% inhibition was observed at 100 microM (n=7). Luminol 127-134 N-methylpurine-DNA glycosylase Rattus norvegicus 0-28 10781007-7 2000 N-2-mercaptopropionylglycine (MPG, 1 microM - 10 mM) produced a concentration-dependent inhibition of peroxynitrite signals in luminol chemiluminescence and 67+/-1% inhibition was observed at 100 microM (n=7). Luminol 127-134 N-methylpurine-DNA glycosylase Rattus norvegicus 30-33 10879688-6 2000 Luminol-dependent (mainly myeloperoxidase (MPO)-mediated) chemiluminescence (CL) response to latex and FMLP (formylmethionylleucylphenylalanine) was also high in these cell populations. Luminol 0-7 myeloperoxidase Homo sapiens 26-41 10879688-6 2000 Luminol-dependent (mainly myeloperoxidase (MPO)-mediated) chemiluminescence (CL) response to latex and FMLP (formylmethionylleucylphenylalanine) was also high in these cell populations. Luminol 0-7 myeloperoxidase Homo sapiens 43-46 11257482-1 2000 We have investigated the chemiluminescence signal of luminol and hydrogen peroxide in the presence of a transition metal (Co(II), Cu(I), Fe(II), Fe(III)) and of a chelator (EDTA, citric acid) in pH 8.5, 9 and 10 borate buffer solutions. Luminol 53-60 mitochondrially encoded cytochrome c oxidase II Homo sapiens 122-128 11030462-1 2000 Human blood platelets decreased luminol-enhanced chemiluminescence of human polymorphonuclear leukocytes (PMNL) stimulated with FMLP or Ca2+-ionophore A23187 by 56 or 47%, respectively. Luminol 32-39 formyl peptide receptor 1 Homo sapiens 128-132 10972584-3 2000 Intracellular respiratory burst activity was studied using luminol-enhanced chemiluminescence in the presence of SOD and catalase, to quench extracellular chemiluminescence activity. Luminol 59-66 superoxide dismutase 1 Homo sapiens 113-116 10972584-3 2000 Intracellular respiratory burst activity was studied using luminol-enhanced chemiluminescence in the presence of SOD and catalase, to quench extracellular chemiluminescence activity. Luminol 59-66 catalase Homo sapiens 121-129 10814971-9 2000 The release of MPO, estimated by the chemiluminescence of the luminol/H(2)O(2) reaction in the supernatant of PMN incubated in the absence and presence of stimuli and absence and presence of cytochalasin B, was also higher for PMN isolated by a density gradient. Luminol 62-69 myeloperoxidase Homo sapiens 15-18 10660664-0 2000 Green tea extract and its polyphenols markedly inhibit luminol-dependent chemiluminescence activated by peroxynitrite or SIN-1. Luminol 55-62 MAPK associated protein 1 Homo sapiens 121-126 10591153-4 1999 Thus, we studied the mechanism of inhibition of neutrophil superoxide (O2*-) generation by pravastatin and found that pravastatin at 0.5 mM inhibited the receptor-mediated tyrosine kinase (TK)-dependent pathway of O2*- generation and also luminol chemiluminescence but not the protein kinase C (PKC)-dependent or the TK- and PKC-independent pathways of O2*- generation in neutrophils. Luminol 239-246 TXK tyrosine kinase Homo sapiens 189-191 10515078-5 1999 By assuming that in an inhibitor-free system the disappearance of radicals takes place via their combination process as well as by their interaction with luminol and/or with luminol-derived species, numerical integration yields a calculated curve of radical concentration versus time in fair agreement with experimental data and a rate-constant value for the combination of radicals of approximately 10(6) M-1 s-1, supporting literature findings according to which primarily superoxide anion radicals are formed. Luminol 174-181 tumor associated calcium signal transducer 2 Homo sapiens 406-413 10602303-1 1999 This study examined the applicability of luminol-dependent chemiluminescence (CL) response of neutrophils to assess the degree of stress of spinal surgery by measuring the capacity of circulating neutrophils to produce reactive oxygen species and the levels of serum cytokines: interleukin(IL)-1beta, IL-6, IL-8, tumour necrosis factor (TNF)-alpha and granulocyte colony stimulating factor (G-CSF). Luminol 41-48 interleukin 1 beta Homo sapiens 278-299 10602303-1 1999 This study examined the applicability of luminol-dependent chemiluminescence (CL) response of neutrophils to assess the degree of stress of spinal surgery by measuring the capacity of circulating neutrophils to produce reactive oxygen species and the levels of serum cytokines: interleukin(IL)-1beta, IL-6, IL-8, tumour necrosis factor (TNF)-alpha and granulocyte colony stimulating factor (G-CSF). Luminol 41-48 interleukin 6 Homo sapiens 301-305 10602303-1 1999 This study examined the applicability of luminol-dependent chemiluminescence (CL) response of neutrophils to assess the degree of stress of spinal surgery by measuring the capacity of circulating neutrophils to produce reactive oxygen species and the levels of serum cytokines: interleukin(IL)-1beta, IL-6, IL-8, tumour necrosis factor (TNF)-alpha and granulocyte colony stimulating factor (G-CSF). Luminol 41-48 C-X-C motif chemokine ligand 8 Homo sapiens 307-311 10602303-1 1999 This study examined the applicability of luminol-dependent chemiluminescence (CL) response of neutrophils to assess the degree of stress of spinal surgery by measuring the capacity of circulating neutrophils to produce reactive oxygen species and the levels of serum cytokines: interleukin(IL)-1beta, IL-6, IL-8, tumour necrosis factor (TNF)-alpha and granulocyte colony stimulating factor (G-CSF). Luminol 41-48 tumor necrosis factor Homo sapiens 313-347 10602303-1 1999 This study examined the applicability of luminol-dependent chemiluminescence (CL) response of neutrophils to assess the degree of stress of spinal surgery by measuring the capacity of circulating neutrophils to produce reactive oxygen species and the levels of serum cytokines: interleukin(IL)-1beta, IL-6, IL-8, tumour necrosis factor (TNF)-alpha and granulocyte colony stimulating factor (G-CSF). Luminol 41-48 colony stimulating factor 3 Homo sapiens 352-389 10602303-1 1999 This study examined the applicability of luminol-dependent chemiluminescence (CL) response of neutrophils to assess the degree of stress of spinal surgery by measuring the capacity of circulating neutrophils to produce reactive oxygen species and the levels of serum cytokines: interleukin(IL)-1beta, IL-6, IL-8, tumour necrosis factor (TNF)-alpha and granulocyte colony stimulating factor (G-CSF). Luminol 41-48 colony stimulating factor 3 Homo sapiens 391-396 10452808-0 1999 A myeloperoxidase-specific assay based upon bromide-dependent chemiluminescence of luminol. Luminol 83-90 myeloperoxidase Homo sapiens 2-17 10452808-5 1999 The MPO-specific reaction is believed to proceed in two steps: (i) the enzymatic generation of hypobromous acid (HOBr) from KBr and H(2)O(2) at pH 5 and (ii) the spontaneous reaction of HOBr and H(2)O(2) with luminol to give a Br-CL signal. Luminol 209-216 myeloperoxidase Homo sapiens 4-7 10366777-3 1999 ROS production, measured using luminol-enhanced chemiluminescence (CL), proved to be rapid, transient, PAF receptor-mediated, and totally dependent on an increase in intracellular Ca2+ ([Ca2+]i) and on the presence of extracellular Ca2+. Luminol 31-38 PCNA clamp associated factor Homo sapiens 103-106 10398565-0 1999 Effect of antioxidants on induction time of luminol luminescence elicited by 3-morpholinosydnonimine (SIN-1). Luminol 44-51 MAPK associated protein 1 Homo sapiens 102-107 10398565-2 1999 Several well-known antioxidants found in biological fluids or cells modify the light profile of the reaction between SIN-1 and luminol. Luminol 127-134 MAPK associated protein 1 Homo sapiens 117-122 9754921-8 1998 The adverse effects may be due to scavenging of free oxygen radicals, or to interference with the interaction between luminol and the myeloperoxidase-H2O2-halide system. Luminol 118-125 myeloperoxidase Bos taurus 134-149 10049713-5 1999 Simulation based on the mechanism suggested revealed that the likely value for the rate constant of the primary step between luminol and superoxide anion radicals producing luminol radicals is 5x10(2)-1x10(3) M-1s-1. Luminol 125-132 tumor associated calcium signal transducer 2 Homo sapiens 209-215 10049713-5 1999 Simulation based on the mechanism suggested revealed that the likely value for the rate constant of the primary step between luminol and superoxide anion radicals producing luminol radicals is 5x10(2)-1x10(3) M-1s-1. Luminol 173-180 tumor associated calcium signal transducer 2 Homo sapiens 209-215 10624708-2 1999 In C57/BL6J mice bearing LLC, the weight of the thymus decreased, the proportion of CD4(+)-positive T lymphocytes and the ratio of CD4+ to CD8+ decreased, luminol-enhanced chemiluminescence of white blood cells in peripheral blood stimulated by zymosan increased, and plaque-forming cells (PFC) decreased. Luminol 155-162 CD4 antigen Mus musculus 84-87 9926363-15 1998 Catalase (CAT) abolishes luminol-, lucigenin- and penicillin-amplified chemiluminescence completely, whereas superoxide dismutase (SOD) has no effect on luminol- or penicillin-amplified chemiluminescence, but enhances lucigenin-amplified chemiluminescence five-fold increasingly with increasing SOD activity. Luminol 25-32 catalase Homo sapiens 0-8 9926363-15 1998 Catalase (CAT) abolishes luminol-, lucigenin- and penicillin-amplified chemiluminescence completely, whereas superoxide dismutase (SOD) has no effect on luminol- or penicillin-amplified chemiluminescence, but enhances lucigenin-amplified chemiluminescence five-fold increasingly with increasing SOD activity. Luminol 25-32 catalase Homo sapiens 10-13 9841834-2 1999 Circulating and platelet-activating factor (PAF)-primed phagocyte luminol luminescence responses to complement-opsonized zymosan were increased in both groups of infected CF and non-CF children relative to uninfected CF children and healthy control children and adults. Luminol 66-73 PCNA clamp associated factor Homo sapiens 16-42 9841834-2 1999 Circulating and platelet-activating factor (PAF)-primed phagocyte luminol luminescence responses to complement-opsonized zymosan were increased in both groups of infected CF and non-CF children relative to uninfected CF children and healthy control children and adults. Luminol 66-73 PCNA clamp associated factor Homo sapiens 44-47 9866686-0 1998 Analysis of prostaglandin G/H synthase-2 inhibition using peroxidase-induced luminol luminescence. Luminol 77-84 prostaglandin-endoperoxide synthase 2 Homo sapiens 12-40 9866686-2 1998 Accordingly, we have exploited the heme-catalyzed hydroperoxidase activity of recombinant hCOX-2 to generate luminescence in the presence of luminol, or a cyclic naphthalene hydrazide, and the substrate arachidonic acid. Luminol 141-148 mitochondrially encoded cytochrome c oxidase II Homo sapiens 90-96 9866686-4 1998 Luminol luminescence was proportional to hCOX-2 concentration and gave accurate Km determinations for arachidonate. Luminol 0-7 mitochondrially encoded cytochrome c oxidase II Homo sapiens 41-47 9823544-3 1998 Purified human gamma-glutamyltransferase (GGT) in the presence of 2 mM glutathione (GSH) and 80 microM transferrin, as an iron source, at pH 7.4 generates ROS, as measured by chemiluminescence of luminol. Luminol 196-203 gamma-glutamyltransferase light chain family member 3 Homo sapiens 15-40 9823544-3 1998 Purified human gamma-glutamyltransferase (GGT) in the presence of 2 mM glutathione (GSH) and 80 microM transferrin, as an iron source, at pH 7.4 generates ROS, as measured by chemiluminescence of luminol. Luminol 196-203 gamma-glutamyltransferase light chain family member 3 Homo sapiens 42-45 9916491-2 1998 Luminol-dependent Chemiluminescence (LmCL) responses were inhibited by a high concentration of IFN-alpha (more than 1 x 10(4) IU/ml) when opsonized zymosan (OZ) and phorbol 12-myristate 13-acetate (PMA) were used as stimulants. Luminol 0-7 interferon alpha 1 Homo sapiens 95-104 9617859-0 1998 Correlations between interleukin-8, and myeloperoxidase or luminol-dependent chemiluminescence in inflamed mucosa of ulcerative colitis. Luminol 59-66 C-X-C motif chemokine ligand 8 Homo sapiens 21-34 9667222-5 1998 Following 300 mg HC, N-formylmethionyl leucyl phenylalanine (fMLP)-induced ROS generation, assayed by measuring chemiluminescence with luminol, decreased significantly at 0.5 hours and reached a nadir at 2 hours (8% of basal, P < .001); thereafter, it gradually recovered, but was still below baseline at 24 hours. Luminol 135-142 formyl peptide receptor 1 Homo sapiens 61-65 9596752-3 1998 As endotoxemia is common in alcohol abusers, we investigated the effect of ethanol (21.7 mmol/liter) on the luminol-amplified chemiluminescence of PMNs and Mphi after endotoxin stimulation and the release of tumor necrosis factor alpha (TNF-alpha) from Mphi. Luminol 108-115 tumor necrosis factor Homo sapiens 237-246 9605577-7 1998 trans-Resveratrol exerted a strong inhibitory effect on reactive oxygen species produced by PMN stimulated with 1 microM formyl methionyl leucyl phenylalamine (fMLP) (IC50 1.3+/-0.13 microM, mean+/-s.e.mean), as evaluated by luminol-amplified chemiluminescence. Luminol 225-232 formyl peptide receptor 1 Homo sapiens 160-164 9617859-6 1998 The levels of IL-8 were closely correlated to luminol-dependent chemiluminescence or myeloperoxidase levels. Luminol 46-53 C-X-C motif chemokine ligand 8 Homo sapiens 14-18 9337863-2 1997 We have explored the possibility that CNO- might be one of the unknown substances responsible for the reported impairment, by urine and uraemic plasma, of neutrophil oxidative metabolism (especially as measured by luminol-enhanced chemiluminescence). Luminol 214-221 biogenesis of lysosomal organelles complex 1 subunit 4 Homo sapiens 38-41 9645394-6 1998 In differentiated U937 (or THP-1) cells, IgG or IgE-opsonized zymosan induced a strong time-dependent luminol-dependent chemiluminescence (LDCL), which was abrogated by SOD and partially inhibited by aminoguanidine or L-NMMA. Luminol 102-109 GLI family zinc finger 2 Homo sapiens 27-32 9645394-6 1998 In differentiated U937 (or THP-1) cells, IgG or IgE-opsonized zymosan induced a strong time-dependent luminol-dependent chemiluminescence (LDCL), which was abrogated by SOD and partially inhibited by aminoguanidine or L-NMMA. Luminol 102-109 superoxide dismutase 1 Homo sapiens 169-172 9458730-11 1998 ANG II also stimulated luminol-enhanced chemiluminescence in endothelial cells. Luminol 23-30 angiotensinogen Rattus norvegicus 0-6 9400825-1 1997 Priming of polymorphonuclear neutrophils (PMN) in whole blood (by tumor necrosis factor alpha and interleukin-8 for enhancement of luminol-dependent chemiluminescence induced by human complement-opsonized zymosan) was stable for 120 min. Luminol 131-138 tumor necrosis factor Homo sapiens 66-93 9400825-1 1997 Priming of polymorphonuclear neutrophils (PMN) in whole blood (by tumor necrosis factor alpha and interleukin-8 for enhancement of luminol-dependent chemiluminescence induced by human complement-opsonized zymosan) was stable for 120 min. Luminol 131-138 C-X-C motif chemokine ligand 8 Homo sapiens 98-111 9415643-6 1997 We measured the generation of superoxide by cytochrome c reduction and myeloperoxidase (MPO) dependent products using peak luminol chemiluminescence. Luminol 123-130 myeloperoxidase Homo sapiens 88-91 9574468-3 1998 The generation of ROS was studied using luminol amplified chemiluminescence (GCL) on isolated glomeruli. Luminol 40-47 germ cell-less 2, spermatogenesis associated Homo sapiens 77-80 9354314-4 1997 Luminol-dependent chemiluminescence and NO generation were measured in polymorphonuclear leukocytes (PMN) and HUVEC and generation of interleukin-1 beta (IL-1beta), tumour necrosis factor-alpha (TNF-alpha), and prostaglandin E2 (PGE2) as well as expression of these cytokines" mRNA were examined in lymphocytes, monocytes, PMN, and HUVEC. Luminol 0-7 interleukin 1 beta Homo sapiens 134-152 9354314-4 1997 Luminol-dependent chemiluminescence and NO generation were measured in polymorphonuclear leukocytes (PMN) and HUVEC and generation of interleukin-1 beta (IL-1beta), tumour necrosis factor-alpha (TNF-alpha), and prostaglandin E2 (PGE2) as well as expression of these cytokines" mRNA were examined in lymphocytes, monocytes, PMN, and HUVEC. Luminol 0-7 interleukin 1 beta Homo sapiens 154-162 9354314-4 1997 Luminol-dependent chemiluminescence and NO generation were measured in polymorphonuclear leukocytes (PMN) and HUVEC and generation of interleukin-1 beta (IL-1beta), tumour necrosis factor-alpha (TNF-alpha), and prostaglandin E2 (PGE2) as well as expression of these cytokines" mRNA were examined in lymphocytes, monocytes, PMN, and HUVEC. Luminol 0-7 tumor necrosis factor Homo sapiens 195-204 9387905-7 1997 All patients showed a normal baseline fMLP-induced luminol-enhanced chemiluminiscence and significantly increased chemiluminescence values after rhG-CSF administration. Luminol 51-58 formyl peptide receptor 1 Homo sapiens 38-42 9337863-3 1997 Luminol-enhanced chemiluminescence generated by human neutrophils derives predominantly from the activity of myeloperoxidase (MPO) which produces hypochlorous acid from H2O2 and Cl-. Luminol 0-7 myeloperoxidase Homo sapiens 109-124 9337863-3 1997 Luminol-enhanced chemiluminescence generated by human neutrophils derives predominantly from the activity of myeloperoxidase (MPO) which produces hypochlorous acid from H2O2 and Cl-. Luminol 0-7 myeloperoxidase Homo sapiens 126-129 9280150-6 1997 We evaluated the PMN respiratory burst in response to stimulation with fMLP, LPS, or phorbol 12-myristate 13-acetate (PMA) by measuring the production of reactive oxygen species (ROS) with both luminol-enhanced chemiluminescence and a cytochrome C reduction assay. Luminol 194-201 formyl peptide receptor 1 Homo sapiens 71-75 9192673-6 1997 In L-Arg-depleted macrophages iNOS generates both O-2 and NO that interact to form the potent oxidant peroxynitrite (ONOO-), which was detected by luminol luminescence and whose formation was blocked by superoxide dismutase, urate, or L-Arg. Luminol 147-154 nitric oxide synthase 2, inducible Mus musculus 30-34 9266497-12 1997 dLPP from strain ATCC 35404 caused an enhanced (0.8-8 micrograms/ml) luminol dependent chemiluminiscence (LDCL) effect in human polymorphonuclear neutrophils (PMN) which could be related to protein concentration. Luminol 69-76 lazaro Drosophila melanogaster 0-4 9147366-7 1997 Superoxide generation was measured by cytochrome c reduction and myeloperoxidase (MPO) products by measurement of peak luminol chemiluminescence (CL). Luminol 119-126 myeloperoxidase Homo sapiens 82-85 9197915-3 1997 The chemiluminescent signal of the oxidation of luminol was detected by means of an MTP reader after 0, 20, 40, 60 and 120 min, respectively, using 200 microM luminol. Luminol 48-55 metallothionein 1B Homo sapiens 84-87 9197915-3 1997 The chemiluminescent signal of the oxidation of luminol was detected by means of an MTP reader after 0, 20, 40, 60 and 120 min, respectively, using 200 microM luminol. Luminol 159-166 metallothionein 1B Homo sapiens 84-87 9108184-4 1997 Interleukin-8 release from alveolar macrophages correlated with the upregulated spontaneous luminol enhanced oxidative response of pulmonary phagocytes but not with the neutrophil count in BALF. Luminol 92-99 C-X-C motif chemokine ligand 8 Homo sapiens 0-13 9025968-3 1997 This first chemiluminescence assay for catalase activity is based on the reaction of luminol (5-amino-2,3-dihydro-1,4-phthalazinedione) and NaOCl. Luminol 85-92 catalase Homo sapiens 39-47 9025968-3 1997 This first chemiluminescence assay for catalase activity is based on the reaction of luminol (5-amino-2,3-dihydro-1,4-phthalazinedione) and NaOCl. Luminol 94-134 catalase Homo sapiens 39-47 8613700-10 1996 Because the lucigenin- and luminol-enhanced chemiluminescence detects, respectively, the O2- production and the myeloperoxidase/hydrogen peroxide halide system, the present data show parallels between deficiency in the production of oxygen-reactive species by PMN and lower fungicidal activity. Luminol 27-34 myeloperoxidase Mus musculus 112-127 8997263-5 1996 After induction of iNOS and production of iNOS-derived NO, ONOO- was detected by luminol-enhanced chemiluminescence and was found to cause lipid peroxidation and to form nitrotyrosine in the cytoskeleton, detected by immunostaining. Luminol 81-88 nitric oxide synthase 2 Rattus norvegicus 42-46 8945907-7 1996 The exposure of pulmonary arteries to NO also resulted in the detection of H2O2 release (by catalase-inhibitable luminol/ peroxidase-chemiluminescence). Luminol 113-120 catalase Bos taurus 92-100 8896420-5 1996 Inhibition of iNOS activity by NG-monomethyl-L-arginine (LNMMA) significantly decreased in vitro U937 cell differentiation with VD and RA/VD as shown by the expression of cell differentiation markers (CD14 and CD68) and by the capacity of these cells to undergo a luminol-dependent chemiluminescence in response to opsonized zymosan. Luminol 264-271 nitric oxide synthase 2 Homo sapiens 14-18 8960464-5 1996 Characteristically, myeloperoxidase deficient granulocytes showed a strikingly decreased luminol-enhanced chemiluminescence while the lucigenin-enhanced chemiluminescence was significantly increased compared to normal granulocytes. Luminol 89-96 myeloperoxidase Homo sapiens 20-35 8929553-1 1996 The neutrophil respiratory burst was examined by the technique of luminol-dependent chemiluminescence (LDCL) triggered by submaximal concentrations of N-formyl-methionyl-leucyl-phenylalanine (fMLP) in diluted whole blood. Luminol 66-73 formyl peptide receptor 1 Homo sapiens 192-196 8890903-0 1996 Application of xanthine oxidase-catalyzed luminol chemiluminescence in a mouse interleukin-5 immunoassay. Luminol 42-49 xanthine dehydrogenase Mus musculus 15-31 8890903-0 1996 Application of xanthine oxidase-catalyzed luminol chemiluminescence in a mouse interleukin-5 immunoassay. Luminol 42-49 interleukin 5 Mus musculus 79-92 8890903-1 1996 A chemiluminescent substrate reagent for use in a sandwich immunoassay for the model antigen mouse interleukin-5 (IL-5) was developed using xanthine oxidase and luminol. Luminol 161-168 interleukin 5 Mus musculus 99-112 8890903-1 1996 A chemiluminescent substrate reagent for use in a sandwich immunoassay for the model antigen mouse interleukin-5 (IL-5) was developed using xanthine oxidase and luminol. Luminol 161-168 interleukin 5 Mus musculus 114-118 8890903-5 1996 The detection limit of the xanthine oxidase-luminol assay was found to be about 0.6 pg/ml IL-5, whereas the peroxidase-catalyzed immunoassays have detection limits of about 1.3 (HRP-TMB) and 2.9 pg/ml (HRP-luminol) IL-5. Luminol 44-51 xanthine dehydrogenase Mus musculus 27-43 8890903-5 1996 The detection limit of the xanthine oxidase-luminol assay was found to be about 0.6 pg/ml IL-5, whereas the peroxidase-catalyzed immunoassays have detection limits of about 1.3 (HRP-TMB) and 2.9 pg/ml (HRP-luminol) IL-5. Luminol 44-51 interleukin 5 Mus musculus 90-94 8774354-5 1996 In addition to these phenotypical changes, IL-4 primed the phorbol-12-myristate-13-acetate (PMA)-induced luminol-dependent chemiluminescence response (LDCL) by normal human monocytes, this priming effect being abrogated in the presence of BW B70C. Luminol 105-112 interleukin 4 Homo sapiens 43-47 9030090-4 1997 METHODS: We compared the ability of P. aeruginosa PLC-H and PLC-N to generate leukotriene B4 (by HPLC) and oxygen (O2-) metabolites (luminol-enhanced chemiluminescence), and to release beta-glucuronidase and histamine (fluorophotometry from human granulocytes. Luminol 133-140 glucuronidase beta Homo sapiens 185-203 9373734-1 1997 In this paper, we examine the effects of SPG, which is a well known BRM, both in vivo and in vitro on the neutrophilic ROS production and the serum opsonic activity by the chemiluminescence technique using luminol as a probe. Luminol 206-213 SPG16 Homo sapiens 41-44 8946217-3 1996 We have studied the effects of TNF-alpha on the priming of F-Met-Leu-Phe (FMLP)-stimulated oxidative metabolism of PMN, using a luminol-enhanced chemiluminescence assay, and have examined the relative roles of PMN receptors for TNF-alpha in priming this oxidative metabolism, using antibodies with p55 and p75 receptor-specific agonistic and antagonistic activities. Luminol 128-135 formyl peptide receptor 1 Homo sapiens 74-78 8905586-6 1996 At physiologic pH, luminol is a highly sensitive, but not specific, probe of myeloperoxidase activity. Luminol 19-26 eosinophil peroxidase Gallus gallus 77-92 9558962-2 1996 We used both lucigenin-dependent CL (LgCL) for superoxide (O2-) detection and luminol-dependent CL (LmCL) which detects myeloperoxidase (MPO)-dependent formation of hypochlorous acid in combination with MPO inhibitor, sodium azide (NaN3). Luminol 78-85 myeloperoxidase Homo sapiens 120-135 8805680-4 1996 In contrast, both myeloperoxidase (MPO)-dependent oxygenation activity (measured by luminol luminescence) and chloramine release were increased significantly in both CF homozygotes and heterozygotes as compared with controls. Luminol 84-91 myeloperoxidase Homo sapiens 18-33 8805680-4 1996 In contrast, both myeloperoxidase (MPO)-dependent oxygenation activity (measured by luminol luminescence) and chloramine release were increased significantly in both CF homozygotes and heterozygotes as compared with controls. Luminol 84-91 myeloperoxidase Homo sapiens 35-38 8889756-6 1996 In contrast, the 5-amino-2,3-dihydro-1,4-phthalazinedione (luminol)-dependent CL response of the neutrophils indicative of the myeloperoxidase (MPO)-mediated formation of highly reactive oxidants was significantly enhanced after exercise. Luminol 17-57 myeloperoxidase Homo sapiens 127-142 8889756-6 1996 In contrast, the 5-amino-2,3-dihydro-1,4-phthalazinedione (luminol)-dependent CL response of the neutrophils indicative of the myeloperoxidase (MPO)-mediated formation of highly reactive oxidants was significantly enhanced after exercise. Luminol 17-57 myeloperoxidase Homo sapiens 144-147 8889756-6 1996 In contrast, the 5-amino-2,3-dihydro-1,4-phthalazinedione (luminol)-dependent CL response of the neutrophils indicative of the myeloperoxidase (MPO)-mediated formation of highly reactive oxidants was significantly enhanced after exercise. Luminol 59-66 myeloperoxidase Homo sapiens 127-142 8889756-6 1996 In contrast, the 5-amino-2,3-dihydro-1,4-phthalazinedione (luminol)-dependent CL response of the neutrophils indicative of the myeloperoxidase (MPO)-mediated formation of highly reactive oxidants was significantly enhanced after exercise. Luminol 59-66 myeloperoxidase Homo sapiens 144-147 8685918-1 1996 The luminol-enhanced chemiluminescence (CL) activity of splenocytes of mice of the strain (CBA x C57B1)F1 was monitored after treatment with Cd2+ (cadmium chloride) in both in vitro and in vivo experiments. Luminol 4-11 CD2 antigen Mus musculus 141-144 8726584-3 1996 The myeloperoxidase (MPO) inhibitor salicylhydroxamic acid (SHA) abrogated luminol but not lucigenin CL in both cell types, but did not further inhibit the already grossly subnormal luminol CL responses seen with MPO-deficient cells which produced normal lucigenin CL. Luminol 75-82 myeloperoxidase Homo sapiens 4-19 8726584-3 1996 The myeloperoxidase (MPO) inhibitor salicylhydroxamic acid (SHA) abrogated luminol but not lucigenin CL in both cell types, but did not further inhibit the already grossly subnormal luminol CL responses seen with MPO-deficient cells which produced normal lucigenin CL. Luminol 75-82 myeloperoxidase Homo sapiens 21-24 8726584-4 1996 SHA also profoundly inhibited the luminol CL response in a cell-free MPO-H2O2 system. Luminol 34-41 myeloperoxidase Homo sapiens 69-72 8726584-7 1996 However, analysis of the effects of various reactive oxygen species (ROS) scavengers, assessed on phagocyte and cell-free CL systems (both MPO-H2O2 and superoxide generating) suggest that the luminol CL signal is not entirely dependent on MPO activity. Luminol 192-199 myeloperoxidase Homo sapiens 139-142 8726584-7 1996 However, analysis of the effects of various reactive oxygen species (ROS) scavengers, assessed on phagocyte and cell-free CL systems (both MPO-H2O2 and superoxide generating) suggest that the luminol CL signal is not entirely dependent on MPO activity. Luminol 192-199 myeloperoxidase Homo sapiens 239-242 8915352-6 1996 Both resting and FMLP-induced luminol-dependent chemiluminescence of rat peritoneal neutrophils increased immediately after treatment with indomethacin. Luminol 30-37 formyl peptide receptor 1 Homo sapiens 17-21 8527265-10 1995 The thiol captopril and MPG (but not enalaprilat) caused an initial delay in luminol chemiluminescence production by PMA-stimulated neutrophils. Luminol 77-84 N-methylpurine DNA glycosylase Homo sapiens 24-27 8582646-1 1995 Nitric oxide synthase (NOS) inhibitors have been reported to modulate luminol-dependent chemiluminescence (CL) in rat macrophages, whereas the potent oxidant peroxynitrite (ONOO-) was shown to react with luminol to yield CL in a cell-free system. Luminol 70-77 nitric oxide synthase 2 Homo sapiens 0-21 8582646-1 1995 Nitric oxide synthase (NOS) inhibitors have been reported to modulate luminol-dependent chemiluminescence (CL) in rat macrophages, whereas the potent oxidant peroxynitrite (ONOO-) was shown to react with luminol to yield CL in a cell-free system. Luminol 204-211 nitric oxide synthase 2 Homo sapiens 0-21 7499967-2 1995 We have employed the technique of receptor cross-linking to study the potential role of CD18, the common beta-subunit of the beta 2-integrin family of adhesion molecules, in the regulation of the respiratory burst, as measured by luminol-enhanced chemiluminescence and iodination, in human neutrophils. Luminol 230-237 lymphotoxin beta receptor Homo sapiens 88-92 7485529-2 1995 TNF treatment decreased luminol and Gfree, and increased GSSG and GSSG/Gfree, compared with treatment with control media. Luminol 24-31 tumor necrosis factor Homo sapiens 0-3 7636266-3 1995 We present evidence that CD45 modulates activation of the inducible respiratory burst in normal human neutrophils, monocytes, and eosinophils, as measured by luminol-enhanced chemiluminescence. Luminol 158-165 protein tyrosine phosphatase receptor type C Homo sapiens 25-29 7639514-4 1995 We found that VP-16 is an effective scavenger of peroxyl radicals as judged by its ability to inhibit a water-soluble azo-initiator, 2,2"-azobis(2-amidinopropane)dihydrochloride (AAPH)-induced (i) chemiluminescence (oxidation) of luminol, (ii) fluorescence decay (oxidation) of cis-parinaric acid incorporated in SR membranes, and (iii) peroxidation of SR membrane lipids. Luminol 230-237 host cell factor C1 Homo sapiens 14-19 8789157-1 1996 In need of a simple and sensitive method for detection of diamine oxidase (EC 1.4.3.6) activity in connection with diamine oxidase purification from human placenta, we have developed an enhanced chemiluminescence method using putrescine as substrate and horseradish peroxidase and luminol for the detection of the H2O2 produced by diamine oxidase. Luminol 281-288 amine oxidase copper containing 1 Homo sapiens 58-73 9007613-4 1996 This had a priming effect, increasing both the Fc gamma receptor-mediated luminol-enhanced chemiluminescence and the membrane expression of the C3bi receptor (CRB) (r = 0.843). Luminol 74-81 Fc gamma receptor Ia Homo sapiens 47-64 8820502-3 1996 We studied the luminol-dependent chemiluminescence (CL) response of PMNs to three different stimulators: phorbol myristate acetate (PMA), formyl-methionyl-leucyl-phenylalanine (FMLP), and opsonized zymosan (OZ). Luminol 15-22 formyl peptide receptor 1 Homo sapiens 177-181 8961380-1 1996 We examined the intracellular mechanisms of substance P induced oxyradical production in rheumatoid synovial cells by the luminol-dependent chemiluminescence method. Luminol 122-129 tachykinin precursor 1 Homo sapiens 44-55 8595934-4 1995 After subsequent stimulation with FMLP (10(-7) M) or opsonized zymosan (0.5 mg/ml) the intra- and extracellular generation of ROS was assessed by luminol-amplified chemiluminescence, superoxide radical (.O2-) and hydrogen peroxide (H2O2) production. Luminol 146-153 formyl peptide receptor 1 Homo sapiens 34-38 8594848-3 1995 Analysis of PMN functions revealed a deficiency in the luminol-enhanced chemiluminescence responses that seemed to be associated with the mobilization of myeloperoxidase (MPO) in the PMN of the patient group, as compared with the healthy controls. Luminol 55-62 myeloperoxidase Homo sapiens 154-169 8594848-3 1995 Analysis of PMN functions revealed a deficiency in the luminol-enhanced chemiluminescence responses that seemed to be associated with the mobilization of myeloperoxidase (MPO) in the PMN of the patient group, as compared with the healthy controls. Luminol 55-62 myeloperoxidase Homo sapiens 171-174 8588512-4 1995 Their light output was, however, greatly increased when horseradish peroxidase or myeloperoxidase was added, showing that the light-generating reaction with isoluminol as well as with luminol is peroxidase-dependent. Luminol 160-167 myeloperoxidase Homo sapiens 82-97 8533891-2 1995 The method was based on the determination of chemiluminescence formed by the reaction of a luminol-ferricyanide mixture in alkaline medium with hydrogen peroxide which is one of the metabolic products of histamine and N tau-methylhistamine formed by diamine oxidase. Luminol 91-98 amine oxidase, copper containing 1 Rattus norvegicus 250-265 7767513-7 1995 Reduction of ferricytochrome c and production of luminol-dependent chemiluminescence via SOD-inhibitable reactions confirmed the spontaneous production of O2-. Luminol 49-56 superoxide dismutase 1 Homo sapiens 89-92 8532139-5 1995 The NO effect was probably not due to mono-ADP-ribosylation of cellular proteins, since the ADP-ribosyltransferase (ADPRT) inhibitors nicotinamide (10 microM-10 microM) and luminol (1 microM-1mM) did not diminish the enhancement of transmitter release seen with NO. Luminol 173-180 poly (ADP-ribose) polymerase 1 Rattus norvegicus 116-121 7664173-1 1995 Luminol-enhanced chemiluminescence (CL) of heterologous neutrophils was used to assess the capacity of a 1-ng/ml concentration of Haemophilus influenzae type b (Hib)-specific antibodies to induce opsonization of Hib with autologous heat-inactivated sera from children immunized with Hib capsular polysaccharide-polyribosylribitolphosphate (Hib-PRP) conjugate vaccine. Luminol 0-7 prion protein Homo sapiens 344-347 7654490-8 1995 Captopril and MPG also did not affect urate production or oxygen consumption by xanthine oxidase which indicated that captopril and MPG quench luminol chemiluminescence by a mechanism that excludes the inhibition of xanthine oxidase. Luminol 143-150 N-methylpurine DNA glycosylase Homo sapiens 132-135 7645982-3 1995 Human myelogenous leukemic cell lines (HL-60, ML-1) showed higher production of active oxygen(s) (detected by luminol chemiluminescence) and iodination capacity, than six other cultured cell lines. Luminol 110-117 interleukin 17F Homo sapiens 46-50 12228480-5 1995 In this study the luminol-dependent chemiluminescent reaction previously used to measure H2O2 levels in suspension cells was modified to allow the assay of both peroxidase and H2O2-scavenging activity. Luminol 18-25 peroxidase N1 Nicotiana tabacum 161-171 7716769-3 1995 Using a water-soluble source of peroxyl radicals, the azo-initiator 2,2"-azobis(2-aminodinopropane) (AAPH), we found that both PMC and VP-16 are very efficient scavengers of peroxyl radicals as evidenced by their ability to inhibit AAPH-induced chemiluminescence of luminol and oxidation of PnA incorporated into DOPC liposomes. Luminol 266-273 host cell factor C1 Homo sapiens 135-140 7744297-1 1995 The effect of antioxidants and biological fluids on the intensity of luminol induced chemiluminescence by radicals derived from the thermolysis of 2,2"-azo-bis(2-amidinopropane) has been employed to monitor TRAP and TOTAL ANTIOXIDANT REACTIVITY (TAR) levels. Luminol 69-76 TRAP Homo sapiens 207-211 7676854-3 1995 for three doses), an antiplatelet agent, on fMLP (formyl-methionyl-leucyl-phenylalanine) stimulated neutrophil aggregation and luminol-dependent chemiluminescence in whole blood. Luminol 127-134 formyl peptide receptor 1 Homo sapiens 44-48 7866335-1 1994 Purified fibrinogen strongly acts as an antioxidant by inhibiting the chemiluminescent emission developed in vitro, in a cell-free system composed of luminol and hydrogen peroxide. Luminol 150-157 fibrinogen beta chain Homo sapiens 9-19 7549522-4 1995 This study examined the effect of recombinant soluble ICAM-1 and its ligands on eosinophil-induced radical oxygen products in terms of luminol-dependent chemiluminescence. Luminol 135-142 intercellular adhesion molecule 1 Homo sapiens 54-60 7549523-3 1995 Adhesion of eosinophils to fibronectin resulted in enhancement of eosinophil production of radical oxygen species, as determined by luminol-dependent chemiluminescence of eosinophils stimulated with calcium ionophore. Luminol 132-139 fibronectin 1 Homo sapiens 27-38 7762419-6 1995 Lucigenin-dependent CL of sulphite-treated and subsequently stimulated neutrophils was strongly inhibited by extracellularly added superoxide dismutase, whereas luminol-dependent CL was markedly reduced by the MPO inhibitor azide. Luminol 161-168 myeloperoxidase Homo sapiens 210-213 8789129-2 1995 A luminol-dependent, fMLP stimulated chemiluminescence system was used and showed that 10(-3) M fluoride significantly increased the inhibitory effect of clodronate (3 ug/ml and 10 ug/ml) when bound to particulate hydroxyapatite (HA), phagocytosed by the neutrophils. Luminol 2-9 formyl peptide receptor 1 Homo sapiens 21-25 8667597-1 1995 A chemiluminescence (CL) procedure was developed to determine the time course of the release of myeloperoxidase (MPO) from activated human neutrophils using two CL probes, luminol, and MCLA. Luminol 172-179 myeloperoxidase Homo sapiens 96-111 8062957-7 1994 CONCLUSION: Leukocyte contamination of human sperm preparations can be detected readily by FMLP-induced, luminol-dependent chemiluminescence and the results have an important bearing on the fertilizing capacity of the spermatozoa in vitro. Luminol 105-112 formyl peptide receptor 1 Homo sapiens 91-95 7549267-6 1995 G-CSF enhanced PMN superoxide anion (O2-) production and luminol-dependent chemiluminescence (CL) induced by opsonized zymosan in a dose-dependent manner. Luminol 57-64 colony stimulating factor 3 Homo sapiens 0-5 7887479-0 1994 Luminol chemiluminescent assay of cytochrome b5. Luminol 0-7 cytochrome b5 type A Homo sapiens 34-47 7919387-1 1994 The effect of nitric oxide (NO) on the luminol-dependent chemiluminescence (LCL) response of rat polymorphonuclear leukocytes (PMNLs) was analyzed by using sodium nitroprusside (SNP), a NO donor, and L-arginine (L-arg), a NO precursor. Luminol 39-46 Rho guanine nucleotide exchange factor 12 Homo sapiens 200-217 7970940-4 1994 Concentrations of IgA as low as 10 mg/L significantly inhibited the receptor-dependent Haemophilus influenzae-induced respiratory burst in granulocytes, as assessed by measuring luminol-enhanced chemiluminescence. Luminol 178-185 CD79a molecule Homo sapiens 18-21 8179319-4 1994 Immediate oxidant production was detected by luminol- and lucigenin-enhanced chemiluminescence from cultured bovine aortic endothelial cells exposed to bradykinin or to the calcium ionophore A23187. Luminol 45-52 kininogen 1 Bos taurus 152-162 8179319-7 1994 Cysteine, methionine, and urate, known inhibitors of peroxynitrite-mediated oxidation, inhibited luminol-enhanced chemiluminescence, while the hydroxyl radical scavengers, mannitol and dimethylsulfoxide, and catalase did not. Luminol 97-104 catalase Bos taurus 208-216 8182511-8 1994 Furthermore, incubation of 10 microM SIN-1 or nitroprusside with luminol in the absence of cells produced no chemiluminescence at these drug concentrations. Luminol 65-72 MAPK associated protein 1 Homo sapiens 37-42 8182343-2 1994 Thirty minutes after superfusion with 10 nM CINC/gro, the number of neutrophils adherent to the venular endothelium and those migrated across the venules were significantly increased with a concomitant elevation of luminol-dependent chemiluminescence at the site of adhesion. Luminol 215-222 C-X-C motif chemokine ligand 1 Rattus norvegicus 44-52 8182343-4 1994 Pretreatments with a CD18-directed monoclonal antibody, WT-3 (1 mg/kg), significantly attenuated the increase in number of adherent and migrated neutrophils, the increase in luminol-dependent chemiluminescence, and the venular macromolecular leakage after the application of CINC/gro. Luminol 174-181 integrin subunit beta 2 Rattus norvegicus 21-25 8177196-4 1994 Measurement of O2- production capacity was used as a reflection of the activity of NADPH oxidase, and the activity of myeloperoxidase-H2O2-halide system was evaluated using luminol-dependent chemiluminescence. Luminol 173-180 myeloperoxidase Homo sapiens 118-133 8066992-2 1994 In this study, we demonstrate that bovine neutrophils undergo a substantially greater luminol-dependent chemiluminescence response to bovine IL-1 beta than to human IL-1 alpha, human IL-1 beta, or murine IL-1 alpha. Luminol 86-93 interleukin 1 beta Bos taurus 141-150 8066992-2 1994 In this study, we demonstrate that bovine neutrophils undergo a substantially greater luminol-dependent chemiluminescence response to bovine IL-1 beta than to human IL-1 alpha, human IL-1 beta, or murine IL-1 alpha. Luminol 86-93 interleukin 1 alpha Mus musculus 204-214 8066992-3 1994 Likewise, approximately 1000-fold less bovine IL-1 beta than human IL-1 beta was required to prime bovine neutrophils for an enhanced luminol-dependent chemiluminescence response to opsonized zymosan particles. Luminol 134-141 interleukin 1 beta Bos taurus 46-55 8066992-3 1994 Likewise, approximately 1000-fold less bovine IL-1 beta than human IL-1 beta was required to prime bovine neutrophils for an enhanced luminol-dependent chemiluminescence response to opsonized zymosan particles. Luminol 134-141 interleukin 1 beta Homo sapiens 67-76 7516248-7 1994 LBP was characterized by N-terminal sequence analysis and by measuring the biological activity using flow cytometry (fluorescence-activated cell sorter, FACS) and a luminol enhanced chemiluminescence (LECL) assay. Luminol 165-172 lipopolysaccharide binding protein Homo sapiens 0-3 8135793-2 1994 In order to test the hypothesis that the nuclear enzyme poly(ADP-ribose)polymerase (PADPRP) plays a role in such a process, a variety of PADPRP inhibitors such as 3-aminobenzamide, nicotinamide, 4-aminobenzamide and luminol were used. Luminol 216-223 poly(ADP-ribose) polymerase 1 Homo sapiens 56-82 8135793-2 1994 In order to test the hypothesis that the nuclear enzyme poly(ADP-ribose)polymerase (PADPRP) plays a role in such a process, a variety of PADPRP inhibitors such as 3-aminobenzamide, nicotinamide, 4-aminobenzamide and luminol were used. Luminol 216-223 poly(ADP-ribose) polymerase 1 Homo sapiens 84-90 7512397-3 1994 RANTES treatment resulted in the enhancement of peak value and integrated value of productivity of eosinophil-mediated radical oxygen products determined by luminol-dependent chemiluminescence of EoL-3 cells stimulated with A23187. Luminol 157-164 C-C motif chemokine ligand 5 Homo sapiens 0-6 8216559-0 1993 Enhanced eosinophil luminol-dependent chemiluminescence and complement receptor expression by platelet-activating factor and interleukin-5. Luminol 20-27 interleukin 5 Homo sapiens 125-138 8047717-3 1994 Luminol-enhanced CL correlated to neutrophil percentage and myeloperoxidase levels in the bronchoalveolar lavage and was markedly increased in both pneumonia groups. Luminol 0-7 myeloperoxidase Homo sapiens 60-75 8116214-0 1993 Effects of in vitro adrenocorticotrophic hormone, cortisol and human recombinant interleukin-2 on porcine neutrophil migration and luminol-dependent chemiluminescence. Luminol 131-138 interleukin 2 Homo sapiens 81-94 8227868-2 1993 Oxidase activation as measured by luminol-dependent chemiluminescence by the receptor-mediated N-formyl-methionyl-leucyl-phenylalanine, phorbol 12-myristate 13-acetate, or the particulate stimulus Staphylococcus aureus was inhibited by IgE with concentrations causing 50% effect of 1.2 +/- 0.13, 1.09 +/- 0.16, and 0.6 +/- 0.09 ng/ml, respectively. Luminol 34-41 immunoglobulin heavy constant epsilon Homo sapiens 236-239 8285109-7 1993 It depended on the presence of hydrogen peroxide in the incubation medium and the incubation time between luminol and catalase. Luminol 106-113 catalase Homo sapiens 118-126 8216378-2 1993 In the present study we measured the inhibition by 34 compounds, either flavonoids or related substances, of the release of reactive oxygen species by human neutrophils after stimulation by three agents: the bacterial peptide N-fMetLeuPhe (FMLP), the protein kinase C activator phorbol myristate acetate (PMA) or opsonized zymosan (OZ), using two chemiluminescent probes, lucigenin or luminol in the presence or absence of horseradish peroxidase (HRP). Luminol 385-392 formyl peptide receptor 1 Homo sapiens 240-244 8216383-2 1993 It is based on measurement of the light production from the peroxidase-catalysed chemiluminescent oxidation of 5-amino-2,3-dihydro-1,4-phthalazinedione (luminol) by the hydrogen peroxide produced in the MAO reaction. Luminol 111-151 monoamine oxidase A Rattus norvegicus 203-206 8216383-2 1993 It is based on measurement of the light production from the peroxidase-catalysed chemiluminescent oxidation of 5-amino-2,3-dihydro-1,4-phthalazinedione (luminol) by the hydrogen peroxide produced in the MAO reaction. Luminol 153-160 monoamine oxidase A Rattus norvegicus 203-206 8250236-2 1993 MPO is determined through its ability to catalyze the oxidation of luminol, resulting in the emission of light which is recorded on a photographic film. Luminol 67-74 myeloperoxidase Homo sapiens 0-3 8268131-6 1993 Morphological and phenotypical changes were associated with functional modifications as CD23 ligation allowed the acquisition of the oxidative metabolism in leukemic cells as revealed by luminol-dependent chemiluminescence. Luminol 187-194 Fc epsilon receptor II Homo sapiens 88-92 8409752-0 1993 Luminol-enhanced chemiluminescence induced in peripheral blood-derived human phagocytes: obligatory requirement of myeloperoxidase exocytosis by monocytes. Luminol 0-7 myeloperoxidase Homo sapiens 115-130 8291204-7 1993 The three forms of bovine MPO were shown to differ in their specific enzyme activities in a luminol-dependent chemiluminescence assay. Luminol 92-99 myeloperoxidase Bos taurus 26-29 8300150-2 1993 Preincubation of cells with rH GM-CSF significantly increased the respiratory burst in response to formyl-methionyl-leucyl-phenylalanine (FMLP), measured by luminol-dependent chemiluminescence (CL) assay. Luminol 157-164 colony stimulating factor 2 Homo sapiens 31-37 8407717-5 1993 The greatest luminol-dependent CL was observed for cell types high in myeloperoxidase (MPO). Luminol 13-20 myeloperoxidase Homo sapiens 70-85 8407717-5 1993 The greatest luminol-dependent CL was observed for cell types high in myeloperoxidase (MPO). Luminol 13-20 myeloperoxidase Homo sapiens 87-90 8407717-9 1993 Taken together, these data suggest that the reaction mechanism of luminol favors interaction with cytoplasmic MPO whereas that of DALM favors membrane interactions. Luminol 66-73 myeloperoxidase Homo sapiens 110-113 8049391-1 1993 The effect of osmolality of the incubation medium on the luminol-amplified chemiluminescence (CL) of human neutrophils stimulated by N-formyl-Met-Len-Phe (FMLP), phorbol-12-myristate-13-acetate (PMA), calcium ionophore A-23187, thermoaggregated IgG (aggIgG) and opsonized zymosan has been studied. Luminol 57-64 formyl peptide receptor 1 Homo sapiens 133-153 7684324-1 1993 Pretreatment of neutrophils with granulocyte colony-stimulating factor (G-CSF) enhanced luminol-dependent chemiluminescence emission by the stimulation of formylmethionylleucylphenylalanine (FMLP), opsonized zymosan, and zymosan. Luminol 88-95 colony stimulating factor 3 Homo sapiens 33-70 7684324-1 1993 Pretreatment of neutrophils with granulocyte colony-stimulating factor (G-CSF) enhanced luminol-dependent chemiluminescence emission by the stimulation of formylmethionylleucylphenylalanine (FMLP), opsonized zymosan, and zymosan. Luminol 88-95 colony stimulating factor 3 Homo sapiens 72-77 8049391-1 1993 The effect of osmolality of the incubation medium on the luminol-amplified chemiluminescence (CL) of human neutrophils stimulated by N-formyl-Met-Len-Phe (FMLP), phorbol-12-myristate-13-acetate (PMA), calcium ionophore A-23187, thermoaggregated IgG (aggIgG) and opsonized zymosan has been studied. Luminol 57-64 formyl peptide receptor 1 Homo sapiens 155-159 8244086-5 1993 Chemiluminescence assays of oxidation of hypoxanthine by xanthine oxidase in the presence of luminol, confirm that the three ACE inhibitors are oxygen free radical scavengers. Luminol 93-100 angiotensin I converting enzyme Homo sapiens 125-128 8469916-2 1993 Maximal luminol enhanced chemiluminescence (CL) of PMN cells after Fc-gamma-receptor stimulation is a way to study the cell activity in connection with phagocytic function. Luminol 8-15 Fc gamma receptor Ia Homo sapiens 67-84 8383401-2 1993 Pretreatment with lidocaine or bupivacaine had a dose-dependent inhibitory effect on PMNG luminol-amplified chemiluminescence stimulated by bovine serum albumin (BSA)/anti-BSA immune complexes (IC) or by serum-opsonized zymosan (SOZ) particles. Luminol 90-97 albumin Homo sapiens 147-160 8210566-2 1993 The luminol-dependent CL response was examined following stimulation with phorbol myristate acetate (PMA) and N-formyl-methionyl-leucyl-phenylalanine (FMLP). Luminol 4-11 formyl peptide receptor 1 Homo sapiens 151-155 8077088-2 1993 The combination of the two agents, used at pharmacological concentrations, was able to increase both the phagocytosis-associated and the f-MLP-induced chemiluminescence, in the presence of luminol as amplifier agent. Luminol 189-196 cysteine and glycine rich protein 3 Homo sapiens 139-142 1459477-0 1992 The inhibitory effects of 21 mimics of superoxide dismutase on luminol-mediated chemiluminescence emitted from PMA-stimulated polymorphonuclear leukocyte. Luminol 63-70 superoxide dismutase 1 Homo sapiens 39-59 8511525-2 1993 Luminol enhanced chemiluminescence (CL) was used to study the interactions of various serogroups of opsonized or nonopsonized meningococci (MC) with polymorphonuclear leukocytes (PMNL), and the results were compared with those of functional (serum bactericidal activity = SBA, phagocytic killing = PK) and nonfunctional (EIA and IFL) antibody tests. Luminol 0-7 interferon alpha 1 Homo sapiens 329-332 1335406-6 1992 Catalase, WR-2721, or Cu(II)2(3,5-DIPS)4 significantly inhibited luminol-enhanced chemiluminescence produced by inflamed colonic mucosa. Luminol 65-72 catalase Homo sapiens 0-8 1331241-2 1992 Of these, the most sensitive were the lucigenin- and luminol-based chemiluminescence assays for O2- and H2O2 respectively. Luminol 53-60 immunoglobulin kappa variable 1D-39 Homo sapiens 96-108 1459477-1 1992 Four groups comprising 21 superoxide dismutase (SOD) mimics synthesized by us were comparatively studied for their inhibitory effects on luminol-mediated chemiluminescence emitted from phorbol myristate acetate (PMA)-stimulated polymorphonuclear leukocyte (PMNL). Luminol 137-144 superoxide dismutase 1 Homo sapiens 26-46 1459477-1 1992 Four groups comprising 21 superoxide dismutase (SOD) mimics synthesized by us were comparatively studied for their inhibitory effects on luminol-mediated chemiluminescence emitted from phorbol myristate acetate (PMA)-stimulated polymorphonuclear leukocyte (PMNL). Luminol 137-144 superoxide dismutase 1 Homo sapiens 48-51 1483581-8 1992 The possibility of employing luminol luminescence in the evaluation of TRAP levels and the capacity of biological samples to scavenge free radicals is discussed. Luminol 29-36 TRAP Homo sapiens 71-75 16653104-7 1992 Preincubation of plant cells with catalase for 2 min before addition of bacteria prevented the increase in CL, confirming that H(2)O(2) is the substrate for the luminol reaction. Luminol 161-168 catalase isozyme 1 Nicotiana tabacum 34-42 1525251-2 1992 The present report describes the determination of luminol- or lucigenin-amplified chemiluminescence of whole blood in a microtitre plate assay with a 96-well luminometer (HAMAMATSU MTP reader). Luminol 50-57 metallothionein 1B Homo sapiens 181-184 1364978-1 1992 The luminol-dependent chemiluminescence activity before and after the ACTH (Synacthen) treatment was investigated in multiple sclerosis patients and the dependence of the changes of chemiluminescence upon the disease course was evaluated. Luminol 4-11 proopiomelanocortin Homo sapiens 70-74 1280902-7 1992 The antioxidant, catalase, inhibited chemiluminescence but superoxide dismutase had no effect, suggesting that luminol-dependent chemiluminescence in chondrocytes mostly measured hydrogen peroxide. Luminol 111-118 catalase Oryctolagus cuniculus 17-25 1332430-3 1992 These combined reductions in O2- generating ability and lower myeloperoxidase levels result in low levels of luminol chemiluminescence stimulated during the respiratory burst of monocytes. Luminol 109-116 myeloperoxidase Homo sapiens 62-77 1328445-1 1992 The acute phase protein, C-reactive protein (CRP), when heat-aggregated (Agg-CRP), potentiates immunoglobulin G (IgG) Fc receptor-mediated luminol-enhanced chemiluminescence (CL) in human monocytes and neutrophils. Luminol 139-146 C-reactive protein Homo sapiens 25-43 1328445-1 1992 The acute phase protein, C-reactive protein (CRP), when heat-aggregated (Agg-CRP), potentiates immunoglobulin G (IgG) Fc receptor-mediated luminol-enhanced chemiluminescence (CL) in human monocytes and neutrophils. Luminol 139-146 C-reactive protein Homo sapiens 45-48 1328445-1 1992 The acute phase protein, C-reactive protein (CRP), when heat-aggregated (Agg-CRP), potentiates immunoglobulin G (IgG) Fc receptor-mediated luminol-enhanced chemiluminescence (CL) in human monocytes and neutrophils. Luminol 139-146 C-reactive protein Homo sapiens 77-80 1384497-6 1992 FMLP-dependent luminol chemiluminescence was also enhanced by G-CSF. Luminol 15-22 colony stimulating factor 3 Homo sapiens 62-67 1319369-4 1992 In ulcerative colitis, luminol chemiluminescence correlated with microscopic inflammation (Spearman"s p = 0.74, P = 0.0001) and was decreased by sodium azide (-89%, P less than 0.05), taurine (-31%, P less than 0.05), catalase (-23%, P less than 0.05), and dimethyl sulfoxide (-29%, P less than 0.05). Luminol 23-30 catalase Homo sapiens 218-226 16668990-4 1992 An IF/cell combination that gives an incompatible reaction in leaves (race 4 IF and Cf 5 cells) showed reduced oxygen uptake and increases in malonaldehyde (a product of lipid peroxidation); cytochrome c reducing activity, which was inhibited by superoxide dismutase (SOD) (an assay for superoxide); luminol-dependent chemiluminescence (an assay for several AO species); activity of extracellular peroxidases; and extracellular phenolic compounds. Luminol 300-307 cytochrome c Solanum lycopersicum 191-203 1456064-1 1992 The stimulatory effect of FMLP 5 nmol.L-1, OAG 25 nmol.L-1 and calcimycin 10 nmol.L-1 on luminol-dependent chemiluminescence (CL) was observed in human neutrophils (Neu). Luminol 89-96 formyl peptide receptor 1 Homo sapiens 26-30 1601157-9 1992 Luminol-dependent, FMLP-induced, chemiluminescence provides a rational basis for monitoring the presence of leukocytes in suspensions of human spermatozoa. Luminol 0-7 formyl peptide receptor 1 Homo sapiens 19-23 1627264-5 1992 It was found that recombinant human IL-1 beta elicited a dose-dependent luminol-enhanced chemiluminescence response in isolated human PMN leukocytes in the dose range 8.8 x 10(-11)-8.8 x 10(-8) M. The effect could be blocked by prior treatment with the IL-1 receptor antagonist, indicating a direct effect on the specific IL-1 receptor. Luminol 72-79 interleukin 1 beta Homo sapiens 36-45 1627264-5 1992 It was found that recombinant human IL-1 beta elicited a dose-dependent luminol-enhanced chemiluminescence response in isolated human PMN leukocytes in the dose range 8.8 x 10(-11)-8.8 x 10(-8) M. The effect could be blocked by prior treatment with the IL-1 receptor antagonist, indicating a direct effect on the specific IL-1 receptor. Luminol 72-79 interleukin 1 receptor antagonist Homo sapiens 253-277 1662316-8 1991 On the other hand, the luminol-enhanced CL, which reflects the myeloperoxidase-dependent oxidative metabolism, and the phagocytic ability of MN was not affected by the hormone. Luminol 23-30 myeloperoxidase Homo sapiens 63-78 1373513-1 1992 Luminol-enhanced chemiluminescence was used to determine the effect of soluble CD14 (sCD14) on the endotoxin-inducible generation of reactive oxygen species in human monocytes. Luminol 0-7 CD14 molecule Homo sapiens 79-83 1668122-5 1991 The method has made it possible to visualize luminol-dependent photonic burst released from PAF-treated microvascular beds in the rat mesentery. Luminol 45-52 PCNA clamp associated factor Rattus norvegicus 92-95 1648400-6 1991 The catalase-sensitive luminol emission of diffusates prepared from axes previously imbibed from 2 to 30 h corresponded to a H2O2 intracellular steady-state concentration in the range of 0.3 to 0.9 microM. Luminol 23-30 catalase-3 Glycine max 4-12 1793562-2 1991 The kinetics of the signal and its modulation by superoxide dismutase, catalase, and horseradish peroxidase are consistent with a series of solution biochemical processes with a rate-determining step corresponding to the disproportionation of a luminol-superoxide complex. Luminol 245-252 catalase Homo sapiens 71-79 1655046-9 1991 The addition of plasma to FMLP-stimulated PMN in the presence of luminol decreases that part of chemiluminescence caused by extracellularly generated hypochlorous acid. Luminol 65-72 formyl peptide receptor 1 Homo sapiens 26-30 1834550-2 1991 The dose-dependent inhibition of the luminol-mediated CL response of human PML to the bacteria was observed in the presence of more than 0.1 mg/ml IgA from both colostrum and serum. Luminol 37-44 CD79a molecule Homo sapiens 147-150 1654817-1 1991 Cytochrome c catalyzed the oxidation of various electron donors in the presence of hydrogen peroxide (H2O2), including 2-2"-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), 4-aminoantipyrine (4-AP), and luminol. Luminol 211-218 cytochrome c, somatic Homo sapiens 0-12 1654817-7 1991 The lack of SOD effect on cytochrome c-catalyzed, H2O2-dependent luminol chemiluminescence supports a mechanism of chemiexcitation whereby a luminol endoperoxide is formed by direct reaction of H2O2 with an oxidized luminol molecule, either luminol radical or luminol diazoquinone. Luminol 65-72 cytochrome c, somatic Homo sapiens 26-38 2169299-4 1990 However, the luminol response decreased form day to day, obviously due to a decrease in the myeloperoxidase (MPO) activity of the cells, whereas the lucigenin response showed no such MPO dependence. Luminol 13-20 myeloperoxidase Homo sapiens 109-112 1660669-9 1991 The luminol analogue phthalhydrazide, which was suggested by Merenyi and Lind as a reliable OH. Luminol 4-11 TNFAIP3 interacting protein 3 Homo sapiens 73-77 2059199-0 1991 Thrombospondin-exposed human monocytes display augmented luminol-enhanced chemiluminescence upon receptor triggering. Luminol 57-64 thrombospondin 1 Homo sapiens 0-14 2059199-2 1991 TSP-treated monocytes displayed luminol-enhanced chemiluminescence (CL) upon triggering with polyclonal or monoclonal anti-TSP. Luminol 32-39 thrombospondin 1 Homo sapiens 0-3 2059199-2 1991 TSP-treated monocytes displayed luminol-enhanced chemiluminescence (CL) upon triggering with polyclonal or monoclonal anti-TSP. Luminol 32-39 thrombospondin 1 Homo sapiens 123-126 2032208-2 1991 SOD activity was measured by a method utilizing reduction in the chemiluminescence of luminol. Luminol 86-93 superoxide dismutase 2, mitochondrial Mus musculus 0-3 1645547-3 1991 Purified mAb 8523 (IgG2b) is able to dose-dependently and specifically stimulate both the basal and the FMLP-induced oxidative burst of intact human PMN, assessed by luminol-amplified chemiluminescence. Luminol 166-173 formyl peptide receptor 1 Homo sapiens 104-108 1828174-1 1991 The N-formylmethionyl-leucyl-phenylalanine (f-MLP)-induced metabolic burst activity of peripheral blood neutrophils isolated from acne patients undergoing treatment with 13-cis-retinoic acid at a dose of 1.0 mg/kg/day was investigated using a luminol-enhanced chemiluminescence assay. Luminol 243-250 cysteine and glycine rich protein 3 Homo sapiens 46-49 1851410-3 1991 Over 95% of the luminol dependent chemiluminescence activated by all samples was inhibited by azide (indicating its dependence upon myeloperoxidase), but anti-(myeloperoxidase) IgG (which specifically inhibits only the extracellular activity of this enzyme) only inhibited the response stimulated by some samples: those fluids which activated the highest luminol dependent chemiluminescence also stimulated the greatest activity of an extracellular myeloperoxidase-H2O2 system. Luminol 16-23 myeloperoxidase Homo sapiens 132-147 1851410-3 1991 Over 95% of the luminol dependent chemiluminescence activated by all samples was inhibited by azide (indicating its dependence upon myeloperoxidase), but anti-(myeloperoxidase) IgG (which specifically inhibits only the extracellular activity of this enzyme) only inhibited the response stimulated by some samples: those fluids which activated the highest luminol dependent chemiluminescence also stimulated the greatest activity of an extracellular myeloperoxidase-H2O2 system. Luminol 16-23 myeloperoxidase Homo sapiens 160-175 1851410-3 1991 Over 95% of the luminol dependent chemiluminescence activated by all samples was inhibited by azide (indicating its dependence upon myeloperoxidase), but anti-(myeloperoxidase) IgG (which specifically inhibits only the extracellular activity of this enzyme) only inhibited the response stimulated by some samples: those fluids which activated the highest luminol dependent chemiluminescence also stimulated the greatest activity of an extracellular myeloperoxidase-H2O2 system. Luminol 16-23 myeloperoxidase Homo sapiens 160-175 1851410-4 1991 A clear correlation was shown to exist between the activity of myeloperoxidase already present in the fluids (after its secretion from neutrophils in situ within the rheumatoid joint) and the ability of the fluid to activate luminol dependent chemiluminescence. Luminol 225-232 myeloperoxidase Homo sapiens 63-78 1654772-2 1991 Since luminol chemiluminescence (LCL) in neutrophils can be blocked by azide, an inhibitor of myeloperoxidase, LCL has been believed to reflect mainly the myeloperoxidase-catalyzed reaction. Luminol 6-13 myeloperoxidase Homo sapiens 94-109 1654772-2 1991 Since luminol chemiluminescence (LCL) in neutrophils can be blocked by azide, an inhibitor of myeloperoxidase, LCL has been believed to reflect mainly the myeloperoxidase-catalyzed reaction. Luminol 6-13 myeloperoxidase Homo sapiens 155-170 1652248-4 1991 However, in the absence of horseradish peroxidase, the luminol-dependent chemiluminescence in the dimethylsulphoxide and butyrate-differentiated HL60 cells was significantly lower than that of the control cells isolated from human blood, reflecting the absence of myeloperoxidase in the differentiated cells. Luminol 55-62 myeloperoxidase Homo sapiens 264-279 1854955-3 1991 TNF-alpha and A23287 synergistically induced both the luminol- and lucigenin-dependent early CL response. Luminol 54-61 tumor necrosis factor Homo sapiens 0-9 1724353-1 1991 Luminol-enhanced chemiluminescence (LECL) was used to determine the effect of soluble CD14 (sCD14) on the endotoxin inducible generation of reactive oxygen species in human monocytes. Luminol 0-7 CD14 molecule Homo sapiens 86-90 2053369-4 1991 Correlations exist between CD3+, CD4+, CD8+ and CD25 + T-Ly and both luminol-dependent CL and neutrophils (p less than 0.01). Luminol 69-76 CD8a molecule Homo sapiens 39-42 2053369-4 1991 Correlations exist between CD3+, CD4+, CD8+ and CD25 + T-Ly and both luminol-dependent CL and neutrophils (p less than 0.01). Luminol 69-76 interleukin 2 receptor subunit alpha Homo sapiens 48-52 2176186-6 1990 The scavenger of reactive oxygen species such as superoxide dismutase, catalase and dimethyl sulphoxide potentiated the effect of the venom on the luminol-dependent chemiluminescence of human phagocyte cells. Luminol 147-154 catalase Homo sapiens 71-79 1979013-1 1990 Incubation of human bloodstream neutrophils with 50 u/ml recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) "primed" the respiratory burst (as assessed by fMet-Leu-Phe stimulated luminol-dependent chemiluminescence) and resulted in a rapid (within 15 min) up-regulation of expression of CD11b and CD18 (as measured by FACS analysis). Luminol 199-206 colony stimulating factor 2 Homo sapiens 69-117 1979013-1 1990 Incubation of human bloodstream neutrophils with 50 u/ml recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) "primed" the respiratory burst (as assessed by fMet-Leu-Phe stimulated luminol-dependent chemiluminescence) and resulted in a rapid (within 15 min) up-regulation of expression of CD11b and CD18 (as measured by FACS analysis). Luminol 199-206 colony stimulating factor 2 Rattus norvegicus 119-126 2169299-4 1990 However, the luminol response decreased form day to day, obviously due to a decrease in the myeloperoxidase (MPO) activity of the cells, whereas the lucigenin response showed no such MPO dependence. Luminol 13-20 myeloperoxidase Homo sapiens 92-107 1721947-2 1991 The method is based on coupled enzymatic reactions in two steps: (1) esterified cholesterol hydrolysis by cholesterol esterase in the presence of sodium cholate and (2) cholesterol oxidation by cholesterol oxidase and chemiluminescent assay of the released hydrogen peroxide in peroxidase reaction with luminol and p-iodophenol. Luminol 303-310 carboxyl ester lipase Homo sapiens 106-126 2169299-5 1990 The luminol response was inhibited by superoxide dismutase (SOD), catalase, and the MPO-inhibitor azide, while the lucigenin response was inhibited by SOD and catalase but stimulated by azide. Luminol 4-11 superoxide dismutase 1 Homo sapiens 38-58 2169299-5 1990 The luminol response was inhibited by superoxide dismutase (SOD), catalase, and the MPO-inhibitor azide, while the lucigenin response was inhibited by SOD and catalase but stimulated by azide. Luminol 4-11 superoxide dismutase 1 Homo sapiens 60-63 2169299-5 1990 The luminol response was inhibited by superoxide dismutase (SOD), catalase, and the MPO-inhibitor azide, while the lucigenin response was inhibited by SOD and catalase but stimulated by azide. Luminol 4-11 catalase Homo sapiens 66-74 2169299-5 1990 The luminol response was inhibited by superoxide dismutase (SOD), catalase, and the MPO-inhibitor azide, while the lucigenin response was inhibited by SOD and catalase but stimulated by azide. Luminol 4-11 myeloperoxidase Homo sapiens 84-87 2383696-2 1990 This system involved separation of phospholipids from LDL-total lipids with normal phase silica gel HPLC and post-column detection of hydroperoxide-dependent chemiluminescence produced by luminol oxidation during the reaction of hydroperoxide with cytochrome c-haeme. Luminol 188-195 cytochrome c, somatic Homo sapiens 248-260 2393956-1 1990 A new type of chemiluminogenic substrate for N-acetyl-beta-D-glucosaminidase, o-aminophthalylhydrazido-N-acetyl-beta-D-glucosaminide, was prepared by incorporating an enzyme-removable substituent, N-acetyl-D-glucosaminide group, into the hydrazide moiety of luminol. Luminol 258-265 O-GlcNAcase Homo sapiens 45-76 2154347-4 1990 In preliminary experiments, the isolated IgG from one patient was shown to inhibit luminol-dependent chemiluminescence of fluid phase myeloperoxidase. Luminol 83-90 myeloperoxidase Homo sapiens 134-149 2363260-1 1990 Effect of some fibronectin preparations on luminol-dependent chemiluminescence of neutrophils was studied. Luminol 43-50 fibronectin 1 Homo sapiens 15-26 2113442-2 1990 Pre-incubation of either monocytes or macrophages with rTNF-alpha or IFN-gamma (100 U/5 x 10(5) cells) augmented their respiratory burst to formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP), measured by the luminol- and lucigenin-dependent chemiluminescence assay. Luminol 208-215 tumor necrosis factor Rattus norvegicus 55-65 2113442-2 1990 Pre-incubation of either monocytes or macrophages with rTNF-alpha or IFN-gamma (100 U/5 x 10(5) cells) augmented their respiratory burst to formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP), measured by the luminol- and lucigenin-dependent chemiluminescence assay. Luminol 208-215 interferon gamma Homo sapiens 69-78 2176907-3 1990 In parallel the expression of myeloperoxidase (MPO) was investigated and its catalytic activity on H2O2 related to luminol-amplified CL responses. Luminol 115-122 myeloperoxidase Homo sapiens 30-45 2176907-3 1990 In parallel the expression of myeloperoxidase (MPO) was investigated and its catalytic activity on H2O2 related to luminol-amplified CL responses. Luminol 115-122 myeloperoxidase Homo sapiens 47-50 34914377-5 2021 With a sandwich immunoreaction mode, a titanium carbide MXene-labeled cTnI tracer antibody was captured on the test line of a test strip, which significantly inhibited the CL response of the Co SACs-boosted luminol system. Luminol 207-214 troponin I3, cardiac type Homo sapiens 70-74 2332192-1 1990 Peroxidation of luminol (5-amino-2,3-dihydrophthalazine-1,4-dione) catalyzed by human green hemoprotein (GHP) and bovine methemoglobin (MetHb) in gels composed of cross-linked bovine serum albumin was examined. Luminol 16-23 hemoglobin subunit gamma 2 Homo sapiens 121-134 2332192-1 1990 Peroxidation of luminol (5-amino-2,3-dihydrophthalazine-1,4-dione) catalyzed by human green hemoprotein (GHP) and bovine methemoglobin (MetHb) in gels composed of cross-linked bovine serum albumin was examined. Luminol 16-23 hemoglobin subunit gamma 2 Homo sapiens 136-141 2332192-1 1990 Peroxidation of luminol (5-amino-2,3-dihydrophthalazine-1,4-dione) catalyzed by human green hemoprotein (GHP) and bovine methemoglobin (MetHb) in gels composed of cross-linked bovine serum albumin was examined. Luminol 25-65 hemoglobin subunit gamma 2 Homo sapiens 121-134 2332192-1 1990 Peroxidation of luminol (5-amino-2,3-dihydrophthalazine-1,4-dione) catalyzed by human green hemoprotein (GHP) and bovine methemoglobin (MetHb) in gels composed of cross-linked bovine serum albumin was examined. Luminol 25-65 hemoglobin subunit gamma 2 Homo sapiens 136-141 2156407-1 1990 The characteristics of the luminol-amplified chemiluminescence (CL) induced in mononuclear phagocytes interacting with PMA, FMLP or ionomycin were determined. Luminol 27-34 formyl peptide receptor 1 Homo sapiens 124-128 1965118-2 1990 The purpose of this study was to investigate the effect of dichloromethylene bisphosphonate, a drug used to modify bone resorption, on extracted neutrophil myeloperoxidase activity directly, and indirectly, by means of a luminol-dependent chemiluminescence assay. Luminol 221-228 myeloperoxidase Homo sapiens 156-171 32797925-0 2020 Development of luminol-fluorescamine-PVP chemiluminescence system and its application to sensitive tyrosinase determination. Luminol 15-22 tyrosinase Homo sapiens 99-109 32797925-6 2020 Inspired by such quenching effect on the luminol-fluorescamine-PVP CL system, a sensitive CL sensing for the determination of tyrosinase activity was developed. Luminol 41-48 tyrosinase Homo sapiens 126-136 34095949-0 2021 G-quadruplex-forming aptamer enhances the peroxidase activity of myoglobin against luminol. Luminol 83-90 myoglobin Homo sapiens 65-74 34812806-5 2021 After the rebinding of PSA onto imprinted cavities, the ECL response of luminol in the solution decreased. Luminol 72-79 kallikrein related peptidase 3 Homo sapiens 23-26 34581826-1 2021 An efficient electrogenerated chemiluminescence (ECL) nanoprobe (luminol-Au NPs-Ti3C2) was constructed based on Ti3C2Tx MXene (Ti3C2)-mediated in situ formation of Au NPs and anchoring luminol to fabricate a sensitive ECL biosensor for miRNA-155 detection. Luminol 65-72 microRNA 155 Homo sapiens 236-245 34581826-1 2021 An efficient electrogenerated chemiluminescence (ECL) nanoprobe (luminol-Au NPs-Ti3C2) was constructed based on Ti3C2Tx MXene (Ti3C2)-mediated in situ formation of Au NPs and anchoring luminol to fabricate a sensitive ECL biosensor for miRNA-155 detection. Luminol 185-192 microRNA 155 Homo sapiens 236-245 34553919-1 2021 Herein, a versatile ECL biosensor was fabricated for ultrasensitive detection of microRNA-21 (miRNA-21) from cancer cells based on a novel H2O2-free electrochemiluminescence (ECL) system (luminol/dissolved oxygen/Fe@Fe2O3 nanowires). Luminol 188-195 microRNA 21 Homo sapiens 81-92 34553919-1 2021 Herein, a versatile ECL biosensor was fabricated for ultrasensitive detection of microRNA-21 (miRNA-21) from cancer cells based on a novel H2O2-free electrochemiluminescence (ECL) system (luminol/dissolved oxygen/Fe@Fe2O3 nanowires). Luminol 188-195 microRNA 21 Homo sapiens 94-102 34283563-4 2021 The ECL resonance energy transfer (ECL-RET) between the hollow manganese dioxide nanospheres and luminol results in a conspicuously decreased ECL signal response, and in the presence of glutathione (GSH), effective redox reaction between manganese dioxide and GSH restores the ECL signal. Luminol 97-104 ret proto-oncogene Homo sapiens 39-42 34812945-3 2021 The as-prepared GOx@Zn-ZIF-67 nanocomposite can trigger cascade reactions of glucose oxidation to generate H2O2 and H2O2-mediated luminol reaction to give an intense CL emission. Luminol 130-137 hydroxyacid oxidase 1 Homo sapiens 16-19 34812945-7 2021 Schematic representation of one-step determination of serum glucose with GOx@Zn-ZIF-67 nanocomposite triggering cascade reactions between luminol and glucose. Luminol 138-145 hydroxyacid oxidase 1 Homo sapiens 73-76 34256261-5 2021 The ratiometric sensing responses ECLDox-luminol/CurrentDox or CurrentMB/CurrentDox linearly regressed to cTnI concentration in the range of 0.1 fM-1 pM or 0.1 fM-500 fM with the limit of detection (LOD) as 0.04 fM or 0.1 fM, respectively. Luminol 40-48 troponin I3, cardiac type Homo sapiens 106-110 34496877-0 2021 A dual-quenched ECL immunosensor for ultrasensitive detection of retinol binding protein 4 based on luminol@AuPt/ZIF-67 and MnO2@CNTs. Luminol 100-107 retinol binding protein 4 Homo sapiens 65-90 34496877-3 2021 In this work, a dual-quenched electrochemiluminescence (ECL) immunosensor has been fabricated for ultrasensitive detection of RBP4 by combining zeolitic imidazolate framework-67/AuPt-supported luminol (luminol@AuPt/ZIF-67) with MnO2 nanosheets-grown on carbon nanotubes (MnO2@CNTs). Luminol 193-200 retinol binding protein 4 Homo sapiens 126-130 34496877-3 2021 In this work, a dual-quenched electrochemiluminescence (ECL) immunosensor has been fabricated for ultrasensitive detection of RBP4 by combining zeolitic imidazolate framework-67/AuPt-supported luminol (luminol@AuPt/ZIF-67) with MnO2 nanosheets-grown on carbon nanotubes (MnO2@CNTs). Luminol 202-209 retinol binding protein 4 Homo sapiens 126-130 34095949-3 2021 In this study, we report G-quadruplex (G4)-forming DNA aptamers that upregulate the peroxidase activity in myoglobin specifically for luminol. Luminol 134-141 myoglobin Homo sapiens 107-116 34095949-4 2021 Using in vitro selection, one G4-forming aptamer that enhanced chemiluminescence from luminol by myoglobin"s peroxidase activity was discovered. Luminol 86-93 myoglobin Homo sapiens 97-106 35546771-4 2022 METHODS: Luminol-dependent chemiluminescence assay was used to evaluate ROS and SIRT1. Luminol 9-16 sirtuin 1 Homo sapiens 80-85 35420408-1 2022 Based on luminol-capped Pt-tipped Au bimetallic nanorods (NRs) (L-Au-Pt NRs) as the anode emitter and SnS2 quantum dots (QDs) hybrid Eu metal organic frameworks (MOFs) (SnS2 QDs@Eu MOFs) as the cathode emitter, a dual-signal electrochemiluminescence (ECL) platform was designed for the ultrasensitive and highly selective detection of kanamycin (KAN). Luminol 9-16 sodium voltage-gated channel alpha subunit 11 Homo sapiens 169-173 35473861-5 2022 Under optimised conditions, the SC-CBP-ECL chips were successfully used for coinstantaneous detection of glucose in double ECL systems (i.e., Ru(bpy)32+ and luminol), with corresponding linear ranges of 0.05-1 mM and 0.05-10 mM, and detection limits of 0.0382 mM and 0.0422 mM. Luminol 157-164 CREB binding protein Homo sapiens 35-38 35078143-3 2022 With glucose and luminol in the reaction mixture, hydrogen peroxide (H2O2) is formed in mesoporous channels by GOx catalysis and then is consumed immediately by PMoV2 to induce CL emission. Luminol 17-24 hydroxyacid oxidase 1 Homo sapiens 111-114 34487166-6 2022 While AtPAP17 also catalyzed the peroxidation of luminol, which was optimal at pH 9.2, it exhibited a low Vmax and affinity for hydrogen peroxide relative to horseradish peroxidase. Luminol 49-56 purple acid phosphatase 17 Arabidopsis thaliana 6-13 35236359-8 2022 When intravenously injected with luminol, MPO-dependent bioluminescence imaging to visualize tissue inflammation was activated by the bioluminescence and fluorescence resonance energy transfer (BRET-FRET) effect. Luminol 33-40 myeloperoxidase Mus musculus 42-45 35099931-2 2022 In this work, for the first time, we explored the use of high entropy oxide (HEO) comprising five metal ingredients (Ni, Co, Cr, Cu, and Fe), to accelerate the reduction reaction of DO into reactive oxygen species (ROS) for boosting the ECL performance of the luminol-DO system. Luminol 260-267 general transcription factor IIE subunit 1 Homo sapiens 137-139 35098710-3 2022 In this work, two kinds of multifunctionalized hydrogel beads, one consisting of chitosan (CS), Co2+, luminol, and gold nanoparticles (AuNPs) (CS-Co2+-Lu-Au), and another consisting of CS, Co2+, luminol, fluorescein, and AuNPs (CS-Co2+-Lu-FL-Au), were prepared via a facile synthesis method. Luminol 195-202 citrate synthase Homo sapiens 143-145 35044176-6 2022 When cardiac troponin I (cTnI), a specific biomarker of acute myocardial infarction, is present, it will be captured by the immobilized cTnI antibodies on the electrode surface, inhibiting electron transfer, resulting in a decrease of the ECL intensity of the luminol-H2O2 system. Luminol 260-267 troponin I3, cardiac type Homo sapiens 5-23 35044176-6 2022 When cardiac troponin I (cTnI), a specific biomarker of acute myocardial infarction, is present, it will be captured by the immobilized cTnI antibodies on the electrode surface, inhibiting electron transfer, resulting in a decrease of the ECL intensity of the luminol-H2O2 system. Luminol 260-267 troponin I3, cardiac type Homo sapiens 25-29 35044176-6 2022 When cardiac troponin I (cTnI), a specific biomarker of acute myocardial infarction, is present, it will be captured by the immobilized cTnI antibodies on the electrode surface, inhibiting electron transfer, resulting in a decrease of the ECL intensity of the luminol-H2O2 system. Luminol 260-267 troponin I3, cardiac type Homo sapiens 136-140 35236359-8 2022 When intravenously injected with luminol, MPO-dependent bioluminescence imaging to visualize tissue inflammation was activated by the bioluminescence and fluorescence resonance energy transfer (BRET-FRET) effect. Luminol 33-40 delta/notch-like EGF repeat containing Mus musculus 194-198 35200371-5 2022 Firstly, luminol-gold NPs (Lum-AuNPs) have been initially built, and then successfully loaded with the fluorescent receptor Chlorin e6 (Ce6) to prepare the luminescent nanoprobes (Ce6@Lum-AuNPs) with green synthesis, i.e., with biocompatible agents and mild temperature. Luminol 9-16 lumican Homo sapiens 27-30 35200371-5 2022 Firstly, luminol-gold NPs (Lum-AuNPs) have been initially built, and then successfully loaded with the fluorescent receptor Chlorin e6 (Ce6) to prepare the luminescent nanoprobes (Ce6@Lum-AuNPs) with green synthesis, i.e., with biocompatible agents and mild temperature. Luminol 9-16 lumican Homo sapiens 184-187 35022642-2 2022 The SI-RAFT polymerization generates polymer chains with functional groups that are used to recruit luminol, enabling strong ECL signal output with low concentrations of miRNA-21, and greatly improving the detection sensitivity. Luminol 100-107 microRNA 21 Homo sapiens 170-178 35053101-4 2022 Blood was collected before, just after, and 1, 3, 5 and 24 h post exercise for determination of absolute and normalized per phagocyte count spontaneous (a-rLBCL, rLBCL) and fMLP-induced luminol-enhanced whole blood chemiluminescence (a-fMLP-LBCL, fMLP-LBCL). Luminol 186-193 formyl peptide receptor 1 Homo sapiens 173-177 2509242-1 1989 Pre-treatment of human neutrophils with rGM-CSF resulted in a 3-fold increase in the rate of fMet-Leu-Phe stimulated reactive oxidant generation, as assessed by luminol- and lucigenin-chemiluminescence and O2- secretion. Luminol 161-168 colony stimulating factor 2 Homo sapiens 44-47 2633824-1 1989 Data are presented concerning peculiarities of human lymphocyte luminol-dependent chemiluminescence stimulated with C3b-opsonized and native zymosan. Luminol 64-71 endogenous retrovirus group K member 3 Homo sapiens 116-119 2511225-3 1989 The present report concerns the effect of recombinant interferon-gamma (rIFN-gamma) on luminol-dependent chemiluminescence, macrophage migration and myelin phagocytosis in organ cultures. Luminol 87-94 interferon gamma Homo sapiens 54-70 2511225-3 1989 The present report concerns the effect of recombinant interferon-gamma (rIFN-gamma) on luminol-dependent chemiluminescence, macrophage migration and myelin phagocytosis in organ cultures. Luminol 87-94 interferon gamma Rattus norvegicus 72-82 2808326-2 1989 Intravital photonic image intensifier microscopy revealed that topical application of PAF-acether (100 nM) caused remarkable granulocyte adherence on endothelial walls and the subsequent activation of a luminol-dependent photonic burst. Luminol 203-210 PCNA clamp associated factor Rattus norvegicus 86-89 2767711-2 1989 The present study illustrates the enhanced sensitivity of these eosinophils for formyl-methionyl-leucylphenylalanine (FMLP) and platelet-activating-factor (PAF) (measured as luminol-enhanced chemiluminescence) compared with eosinophils isolated from the peripheral blood of normal individuals. Luminol 174-181 PCNA clamp associated factor Homo sapiens 128-154 2767711-2 1989 The present study illustrates the enhanced sensitivity of these eosinophils for formyl-methionyl-leucylphenylalanine (FMLP) and platelet-activating-factor (PAF) (measured as luminol-enhanced chemiluminescence) compared with eosinophils isolated from the peripheral blood of normal individuals. Luminol 174-181 PCNA clamp associated factor Homo sapiens 156-159 2769233-2 1989 We have analysed the effect of IFN-alpha/beta on the respiratory burst capacity of mouse peritoneal macrophages by luminol-dependent chemiluminescence using phorbol myristate acetate as trigger. Luminol 115-122 interferon alpha Mus musculus 31-40 2617555-0 1989 [The possibility for determining haptoglobin phenotypes in blood stains after treatment with a luminol solution]. Luminol 95-102 haptoglobin Homo sapiens 33-44 2617555-1 1989 The paper gives the results of tests for influence of luminol solution of different composition on detectability of haptoglobin fractions in the bloodstains of different ages. Luminol 54-61 haptoglobin Homo sapiens 116-127 2801234-4 1989 In the CL-HPLC method, a cytochrome c-luminol mixture was used as a hydroperoxide-specific luminescent reagent, and the quantification of hydroperoxide was performed by detecting chemiluminescence due to the luminol oxidation caused by the oxidant produced during the lipid hydroperoxides with heme. Luminol 38-45 cytochrome c, somatic Homo sapiens 25-37 2543635-4 1989 In vitro, levels of dapsone easily achieved in vivo inhibited myeloperoxidase (MPO)-mediated reactions involving the oxidation of halides to reactive cytotoxic hypohalites (such as MPO-mediated iodination and luminol-enhanced chemiluminescence). Luminol 209-216 myeloperoxidase Rattus norvegicus 62-77 2543635-4 1989 In vitro, levels of dapsone easily achieved in vivo inhibited myeloperoxidase (MPO)-mediated reactions involving the oxidation of halides to reactive cytotoxic hypohalites (such as MPO-mediated iodination and luminol-enhanced chemiluminescence). Luminol 209-216 myeloperoxidase Rattus norvegicus 79-82 2543635-4 1989 In vitro, levels of dapsone easily achieved in vivo inhibited myeloperoxidase (MPO)-mediated reactions involving the oxidation of halides to reactive cytotoxic hypohalites (such as MPO-mediated iodination and luminol-enhanced chemiluminescence). Luminol 209-216 myeloperoxidase Rattus norvegicus 181-184 2552755-1 1989 The granulocyte luminol-dependent chemiluminescence (CL) reaction is linked to the enzyme myeloperoxidase reacting with products of the respiratory burst activation. Luminol 16-23 myeloperoxidase Homo sapiens 90-105 2801234-4 1989 In the CL-HPLC method, a cytochrome c-luminol mixture was used as a hydroperoxide-specific luminescent reagent, and the quantification of hydroperoxide was performed by detecting chemiluminescence due to the luminol oxidation caused by the oxidant produced during the lipid hydroperoxides with heme. Luminol 208-215 cytochrome c, somatic Homo sapiens 25-37 2544040-3 1989 In contrast, luminol-amplified chemiluminescence increased 24 hr following ozone exposure, coinciding with an increase in the percentage of neutrophils and myeloperoxidase in the inflammatory cell population. Luminol 13-20 myeloperoxidase Rattus norvegicus 156-171 2544040-4 1989 Supporting the involvement of myeloperoxidase in the enhanced oxidant-generating status of these cells, the luminol-amplified chemiluminescence was found to be azide-, but not superoxide dismutase-inhibitable. Luminol 108-115 myeloperoxidase Rattus norvegicus 30-45 2544040-6 1989 Addition of myeloperoxidase to control alveolar macrophages resulted in enhanced luminol-amplified chemiluminescence, taurine chloramine generation, and enhanced chemiluminescence from benzo[a]pyrene-7,8-dihydrodiol demonstrating that, in the presence of myeloperoxidase, alveolar macrophages are capable of supporting myeloperoxidase-dependent reactions. Luminol 81-88 myeloperoxidase Rattus norvegicus 12-27 2619731-1 1989 Treatment of polymorphonuclear leukocytes with the soluble and cell penetrating thiol N-(2-mercaptopropionyl)-glycine (2-MPG) inhibits luminol-enhanced chemiluminescence induced by opsonized zymosan, which is believed to be a measure for the generation of reactive oxygen species, and accelerates the rate of phagocytosis measured as ingestion of zymosan particles. Luminol 135-142 N-methylpurine DNA glycosylase Homo sapiens 121-124 2736103-2 1989 We studied the effects of different variables on luminol-enhanced chemiluminescence (CL) of whole blood, induced by N-formyl-methionyl-leucyl-phenylalanine (FMLP), opsonized zymosan particles (OZP), or phosphate buffered saline (PBS). Luminol 49-56 formyl peptide receptor 1 Homo sapiens 157-161 2500671-4 1989 An oxidant scavenging mechanism is also inferred from the fact that heparin is capable of inhibiting luminol-dependent chemiluminescence resulting from the reduction of 15-HPETE by methemoglobin. Luminol 101-108 hemoglobin subunit gamma 2 Homo sapiens 181-194 2545879-1 1989 When neutrophils were stimulated with f-met-leu-phe (fMLP) or phorbol myristate acetate (PMA) chemiluminescence (CL) augmented with luminol, lucigenin or 7-dimethylamino-naphthalene-1,2-dicarbonic acid hydrazide (DMNH) showed a strong dependence on the pH of the medium. Luminol 132-139 formyl peptide receptor 1 Homo sapiens 53-57 2535790-0 1989 Comparison of the effects of superoxide dismutase and cytochrome c on luminol chemiluminescence produced by xanthine oxidase-catalyzed reactions. Luminol 70-77 cytochrome c, somatic Homo sapiens 54-66 2535790-1 1989 Superoxide dismutase (superoxide: superoxide oxidoreductase, EC 1.15.1.1) (SOD) and ferricytochrome c are used to check the effects on luminol chemiluminescence induced by a xanthine or hypoxanthine/xanthine oxidase/oxygen system. Luminol 135-142 superoxide dismutase 1 Homo sapiens 75-78 2543650-1 1989 Cultured porcine retinal pigment epithelial cells release superoxide, measured as superoxide dismutase (SOD)-suppressible reduction of cytochrome C, and SOD-suppressible luminol-dependent chemiluminescence. Luminol 170-177 superoxide dismutase 1 Homo sapiens 153-156 2538105-2 1989 As luminol dependent chemiluminescence largely measures the activity of the myeloperoxidase-H2O2 system, and as the extracellular activity of this enzyme may be responsible for the tissue damage associated with inflammatory conditions such as rheumatoid arthritis, the aim of this work was to distinguish between intracellular and extracellular chemiluminescence so that the extracellular activity of this enzyme could be evaluated. Luminol 3-10 myeloperoxidase Homo sapiens 76-91 3192270-2 1988 This study concerns the effect of FN exposure on the respiratory burst of normal human peripheral phagocytes, using a luminol-dependent chemiluminescence (CL) assay for measurement of reactive oxygen metabolites generated. Luminol 118-125 fibronectin 1 Homo sapiens 34-36 2559930-1 1989 Luminol-enhanced chemiluminescence assay was used to detect the surface expression and the consequent activation of receptors (FcRI and FcRII) of murine macrophages (M phi s). Luminol 0-7 Fc receptor, IgG, high affinity I Mus musculus 127-131 2559930-1 1989 Luminol-enhanced chemiluminescence assay was used to detect the surface expression and the consequent activation of receptors (FcRI and FcRII) of murine macrophages (M phi s). Luminol 0-7 Fc receptor, IgG, low affinity IIb Mus musculus 136-141 2559930-2 1989 When murine IgG2a was used for the specific detection of FcRI and IgG2b for FcRII, a newly established procedure enabled us to detect the activation of each receptor with as few as 3 X 10(5) M phi s. Briefly, TNP-SRBC coated with monoclonal IgG2a or IgG2b antibodies directed to TNP (sensitized SRBC) were used as reagent, in the presence of 1 X 10(-5) M luminol, and the emission was measured with a liquid scintillation counter. Luminol 355-362 Fc receptor, IgG, low affinity IIb Mus musculus 76-81 2806945-5 1989 The chemiluminescence is produced by luminol oxidation during a reaction of hydroperoxide and cytochrome c-heme. Luminol 37-44 cytochrome c, somatic Homo sapiens 94-106 3178847-5 1988 Antibodies to surface-bound Fg were able to induce luminol-dependent chemiluminescence, indicating that Fg binding sites have receptor function. Luminol 51-58 fibrinogen beta chain Homo sapiens 28-30 3178847-5 1988 Antibodies to surface-bound Fg were able to induce luminol-dependent chemiluminescence, indicating that Fg binding sites have receptor function. Luminol 51-58 fibrinogen beta chain Homo sapiens 104-106 3344932-12 1988 Indomethacin inhibited prostaglandin E2 release, and luminol-enhanced, myeloperoxidase-mediated chemiluminescence of activated PMN. Luminol 53-60 myeloperoxidase Homo sapiens 71-86 2843175-0 1988 Luminol-dependent photoemission from single neutrophil stimulated by phorbol ester and calcium ionophore--role of degranulation and myeloperoxidase. Luminol 0-7 myeloperoxidase Homo sapiens 132-147 2843175-5 1988 These findings suggest a prerequisite role of degranulation and myeloperoxidase release in luminol-dependent photoemission from stimulated neutrophils. Luminol 91-98 myeloperoxidase Homo sapiens 64-79 2846518-3 1988 CL was produced through luminol oxidation during the reaction of the hydroperoxide and cytochrome c-heme. Luminol 24-31 cytochrome c, somatic Homo sapiens 87-99 2855072-2 1988 Preincubation of PMNs for 10 min at 37 degrees C with silybin inhibited, in a dose-dependent way, the luminol-enhanced chemiluminescence (CL) generated by stimulated cells without affecting the non-enhanced CL or superoxide anion production evaluated by the cytochrome C reduction assay. Luminol 102-109 cytochrome c, somatic Homo sapiens 258-270 2855072-5 1988 Catalase, a scavenger of H2O2, inhibited luminol-enhanced CL to a similar degree as silybin; moreover, when incubated together with PMNs, silybin and catalase did not produce an additive inhibition of CL. Luminol 41-48 catalase Homo sapiens 0-8 2855072-5 1988 Catalase, a scavenger of H2O2, inhibited luminol-enhanced CL to a similar degree as silybin; moreover, when incubated together with PMNs, silybin and catalase did not produce an additive inhibition of CL. Luminol 41-48 catalase Homo sapiens 150-158 3262598-1 1988 The effects of oral administration of ascorbate (3 grams daily for 14 days) on the elastase inhibitory capacity (EIC) of serum alpha-1-protease inhibitor (API) and on the profile of leukoattractant (FMLP) activated luminol-enhanced chemiluminescence (LECL) responses of blood from 29 cigarette smokers were investigated in a placebo-controlled, doubleblind crossover trial. Luminol 215-222 formyl peptide receptor 1 Homo sapiens 199-203 3132577-1 1988 During exposure to the leukoattractant FMLP (N-formyl-L-methionyl-L-leucyl-L-phenylalanine) human polymorphonuclear leukocytes (PMNL) exhibit a bimodal pattern of luminol-enhanced chemiluminescence (LECL) with distinct early extracellular and later-occurring intracellular membrane-associated oxidative responses [4, 7, 14]. Luminol 163-170 formyl peptide receptor 1 Homo sapiens 39-43 2850722-6 1988 From these results it can be concluded that there are at least two different light-generating mechanisms in FMLP-induced luminol-dependent chemiluminescence of neutrophil cytoplasts. Luminol 121-128 formyl peptide receptor 1 Homo sapiens 108-112 2827790-0 1987 [Characteristics of luminol chemiluminescence induced by the catalytic action of myeloperoxidase]. Luminol 20-27 myeloperoxidase Homo sapiens 81-96 2827790-1 1987 The effects of pH, luminol myeloperoxidase and hydrogen peroxide concentrations on the intensity of luminol chemiluminescence induced by myeloperoxidase catalysis were investigated. Luminol 19-26 myeloperoxidase Homo sapiens 137-152 2827790-6 1987 Luminol oxidation in the course of the myeloperoxidase reaction is induced by hypochlorite. Luminol 0-7 myeloperoxidase Homo sapiens 39-54 3108018-4 1987 Exposure to rIFN-gamma led to an enhanced chemiluminescence (CL) signal in the presence of luminol and a variety of respiratory burst stimuli, such as zymosan, phorbol 12-myristate 13-acetate or IgG-sensitized sheep erythrocytes (EA). Luminol 91-98 interferon gamma Rattus norvegicus 12-22 3034109-1 1987 The bimodal pattern of N-formyl-methionyl-leucyl-phenylalanine (FMLP)-activated luminol-enhanced chemiluminescence with distinct early (occurring within 1 min) extracellular and late intracellular oxidative responses was compared in polymorphonuclear leukocytes (PMNL) from asymptomatic cigarette smokers and nonsmoking control subjects. Luminol 80-87 formyl peptide receptor 1 Homo sapiens 64-68 3031304-1 1987 The role of myeloperoxidase in luminol- and lucigenin-dependent chemiluminescence of stimulated human neutrophils has been investigated using purified myeloperoxidase and anti-(human myeloperoxidase) antiserum. Luminol 31-38 myeloperoxidase Homo sapiens 12-27 3498025-2 1987 Stimulation of the cells by zymosan showed that the potency of producing luminol-dependent chemiluminescence had been markedly increased in the CSF-treated cells, indicating increased generation of active oxygen species in these cells. Luminol 73-80 colony stimulating factor 2 (granulocyte-macrophage) Mus musculus 144-147 3032204-3 1987 Amplified chemiluminescence (CL) allows detection of O-2 using lucigenin (LgCL) or H2O2 using luminol (LuCL). Luminol 94-101 immunoglobulin kappa variable 1D-39 Homo sapiens 53-56 3034003-5 1987 Administration of a single 1 gram oral dose of ascorbate to adult human volunteers was associated with significant reduction and enhancement respectively of the extracellular and intracellular luminol-enhanced chemiluminescence responses of FMLP-activated blood. Luminol 193-200 formyl peptide receptor 1 Homo sapiens 241-245 3031304-3 1987 The results show that luminol-dependent chemiluminescence is largely dependent on both oxidase activity and degranulation (of myeloperoxidase), while lucigenin monitors oxidase activity independently of the extent of degranulation. Luminol 22-29 myeloperoxidase Homo sapiens 126-141 3025094-11 1986 These findings may explain the increased luminol-dependent CL since this type of CL requires the presence of MPO. Luminol 41-48 myeloperoxidase Homo sapiens 109-112 3004423-0 1985 Chemiluminescence of luminol caused by interaction of cytochrome P-450 and cytochrome C with cumene hydroperoxide: comparative studies. Luminol 21-28 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 54-70 2427462-1 1986 Investigations on the effect of a naturally occurring neuropeptide, substance P (SP) and one of its synthetic analogues, 4-11 SP, on luminol-enhanced chemiluminescence (CL) of human polymorphonuclear leukocytes (PMN) are presented. Luminol 133-140 tachykinin precursor 1 Homo sapiens 68-79 3588695-2 1986 Metabolic activity, determined by chemiluminescence (CL) of cells challenged with luminol (5-amino-2,3-dihydro-1,4-phthalazinedione) linked to bovine serum albumin, was detected with a brightness photometer. Luminol 82-89 albumin Homo sapiens 150-163 3588695-2 1986 Metabolic activity, determined by chemiluminescence (CL) of cells challenged with luminol (5-amino-2,3-dihydro-1,4-phthalazinedione) linked to bovine serum albumin, was detected with a brightness photometer. Luminol 91-131 albumin Homo sapiens 150-163 2425843-6 1986 MA1 and MA3 inhibit MPO activities such as tetraguaiacol formation, iodide oxidation and luminol-dependent chemiluminescence, while MB1 shows no such inhibition. Luminol 89-96 PNMA family member 1 Homo sapiens 0-3 2425843-6 1986 MA1 and MA3 inhibit MPO activities such as tetraguaiacol formation, iodide oxidation and luminol-dependent chemiluminescence, while MB1 shows no such inhibition. Luminol 89-96 PNMA family member 3 Homo sapiens 8-11 2425843-6 1986 MA1 and MA3 inhibit MPO activities such as tetraguaiacol formation, iodide oxidation and luminol-dependent chemiluminescence, while MB1 shows no such inhibition. Luminol 89-96 myeloperoxidase Homo sapiens 20-23 3936117-2 1985 Here the presence of 5-lipoxygenase activity in the whole ovary and in the Graafian follicle is estimated by a chemiluminescence assay using unlabeled arachidonic acid as substrate in the presence of luminol and by conversion of 14C-arachidonic acid into lipoxygenase products as separated by HPLC. Luminol 200-207 arachidonate 5-lipoxygenase Rattus norvegicus 21-35 3004423-0 1985 Chemiluminescence of luminol caused by interaction of cytochrome P-450 and cytochrome C with cumene hydroperoxide: comparative studies. Luminol 21-28 cytochrome c, somatic Homo sapiens 75-87 3004423-1 1985 A comparative study of the interaction of cumene hydroperoxide with cytochrome P-450LM2 and with cytochrome C has been undertaken using the chemiluminescence method in the presence of luminol. Luminol 184-191 cytochrome c, somatic Homo sapiens 97-109 6427320-1 1984 The chemiluminescent reaction of luminol during lipoxygenase-catalyzed oxygenations was studied with the purpose of developing a specific luminometric assay for cis,cis-1,4-pentadiene fatty acids directly in aqueous solutions. Luminol 33-40 linoleate 9S-lipoxygenase-4 Glycine max 48-60 2995254-2 1985 Human blood leukocytes generate intense luminol-dependent chemiluminescence (LDCL) following stimulation by streptococci and by Gram negative rods which had been preopsonized by cationic polyelectrolytes (histone, poly L-arginine-PARG, poly L-histidine-PHSTD). Luminol 40-47 poly(ADP-ribose) glycohydrolase Homo sapiens 230-234 6370508-0 1984 Chemiluminescent immunosorbent assay of serum myoglobin based on the luminol reaction. Luminol 69-76 myoglobin Homo sapiens 46-55 6370508-2 1984 Myoglobin was determined in the range of 10-500 micrograms/1 by the chemiluminescent luminol reaction after adsorption to anti-myoglobin IgG onto a solid phase. Luminol 85-92 myoglobin Homo sapiens 0-9 6325341-4 1984 The sequence of addition of the various agents to WBC in the presence of luminol absolutely determined the intensity of the LDCL signals obtained, the highest reactions being achieved when the WBC were preincubated for 2-3 min with A23187 followed by the sequential addition of fMLP, PARG, and PHA. Luminol 73-80 poly(ADP-ribose) glycohydrolase Homo sapiens 284-288 6098130-4 1984 From these results it was concluded that the luminol- and the lucigenin-dependent chemiluminescence differed in the dependence of MPO. Luminol 45-52 myeloperoxidase Homo sapiens 130-133 6487320-1 1984 A method for investigating the cellular response of polymorphonuclear leukocytes to various stimuli was introduced using simultaneously native (luminol-independent) and luminol dependent luminescence as an indicator for myeloperoxidase (MPO)-H2O2-halide and O2- mediated reactions. Luminol 144-151 myeloperoxidase Homo sapiens 220-235 6487320-1 1984 A method for investigating the cellular response of polymorphonuclear leukocytes to various stimuli was introduced using simultaneously native (luminol-independent) and luminol dependent luminescence as an indicator for myeloperoxidase (MPO)-H2O2-halide and O2- mediated reactions. Luminol 169-176 myeloperoxidase Homo sapiens 220-235 6329953-2 1984 Luminol-dependent light emission from PMNL is linked to the myeloperoxidase (MPO)-H2O2 system. Luminol 0-7 myeloperoxidase Homo sapiens 60-75 6329953-2 1984 Luminol-dependent light emission from PMNL is linked to the myeloperoxidase (MPO)-H2O2 system. Luminol 0-7 myeloperoxidase Homo sapiens 77-80 6724877-1 1984 In the absence of cytochalasin B, synthetic Paf-acether (0.1-10 microM) induced oxygen radical production in polymorphonuclear neutrophils as measured by the luminol-dependent chemiluminescence ( LDCL ) test. Luminol 158-165 PCNA clamp associated factor Homo sapiens 44-47 6325346-5 1984 When luminol-dependent-granulocyte chemiluminescence (CL) was studied, FMoxLP was observed to be a more potent stimulus of this response than FMLP. Luminol 5-12 formyl peptide receptor 1 Homo sapiens 142-146 6427320-2 1984 The addition of picomole levels of either linoleic or arachidonic acids to reaction systems containing 0.04 mM luminol and 40 micrograms/ml of purified soybean lipoxygenase-1 gave light emission curves with a single sharp maximum. Luminol 111-118 linoleate 9S-lipoxygenase-4 Glycine max 160-172 6094369-6 1984 The dependence of luminol-amplified CL upon the generation of the chain reaction intermediate H2O2 and its three main catalysts catalase, myeloperoxidase and glutathione makes this reaction prone to different artifacts if cell activity is to be determined. Luminol 18-25 myeloperoxidase Mus musculus 138-153 6195265-5 1983 Although the polyanions heparin and dextran sulfate were effective in inhibiting luminol-dependent myeloperoxidase-H2O2-chloride chemiluminescence, the uncharged polysaccharide dextran T500 was without effect. Luminol 81-88 myeloperoxidase Homo sapiens 99-114 6309658-8 1983 Studies with scavengers of oxygen intermediates and inhibitors of myeloperoxidase for the oxidation of luminol, which may occur in part through the formation of HOCl as well as through a non-HOCl-mediated mechanism. Luminol 103-110 myeloperoxidase Homo sapiens 66-81 6308951-0 1983 Role of myeloperoxidase in the luminol-dependent chemiluminescence response of phagocytosing human monocytes. Luminol 31-38 myeloperoxidase Homo sapiens 8-23 6308951-2 1983 A parallel decline in myeloperoxidase (MPO)-activity of monocyte cell lysates was observed during the same period, and a close correlation was found between peak luminol-dependent CL-response and MPO-activity. Luminol 162-169 myeloperoxidase Homo sapiens 196-199 6305176-3 1983 This study demonstrates the ability of ketamine, an injectable anesthetic, to interfere with the cytotoxic neutrophil myeloperoxidase-H2O2-Cl- reaction, as tested using a luminol-enhanced chemiluminescence assay. Luminol 171-178 myeloperoxidase Homo sapiens 118-133 6299947-0 1983 Role of myeloperoxidase in luminol-dependent chemiluminescence of polymorphonuclear leukocytes. Luminol 27-34 myeloperoxidase Homo sapiens 8-23 6299947-7 1983 This indicated that luminol-dependent chemiluminescence is dependent on and directly related to the presence of myeloperoxidase in PMNL and that both intra- and extracellularly located myeloperoxidase has to be taken into account when interpreting the cellular response assayed as chemiluminescence. Luminol 20-27 myeloperoxidase Homo sapiens 112-127 6299947-7 1983 This indicated that luminol-dependent chemiluminescence is dependent on and directly related to the presence of myeloperoxidase in PMNL and that both intra- and extracellularly located myeloperoxidase has to be taken into account when interpreting the cellular response assayed as chemiluminescence. Luminol 20-27 myeloperoxidase Homo sapiens 185-200 6291348-0 1982 Antioxidation theory of non-steroidal anti-inflammatory drugs based upon the inhibition of luminol-enhanced chemiluminescence from the myeloperoxidase reaction. Luminol 91-98 myeloperoxidase Homo sapiens 135-150 6291348-9 1982 In this study, NSAIDs from various classes were tested for their ability to inhibit luminol-enhanced CL from MPO. Luminol 84-91 myeloperoxidase Homo sapiens 109-112 6607218-9 1984 C5a generation in test sera was proportional to its opsonic activity for HiTb as assessed by a luminol-chemiluminescence assay. Luminol 95-102 complement C5a receptor 1 Homo sapiens 0-3 6195265-4 1983 This inhibition is due to a combination of the diminished release of myeloperoxidase and the scavenging of the luminol oxidant generated by the myeloperoxidase-H2O2-chloride system. Luminol 111-118 myeloperoxidase Homo sapiens 144-159 6615726-3 1983 Luminol amplified luminescence was consistently low in B12-deficient subjects with RBC counts of less than 2 X 10(12)/l. Luminol 0-7 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 55-58 6687603-1 1983 The luminol-dependent chemiluminescence (CL) of neutrophils phagocytosing zymosan is inhibited by superoxide dismutase (SOD), catalase, sodium benzoate, and 2,5-dimethyl furan. Luminol 4-11 catalase Homo sapiens 126-134 6282074-4 1982 Non-steroidal anti-inflammatory drugs (NSAIDs) able to act as antioxidant free radical scavengers have recently been shown to inhibit luminol-enhanced chemiluminescence (CL) which results from the MPO-H2O2-Cl- reaction. Luminol 134-141 myeloperoxidase Homo sapiens 197-200 7024025-11 1981 Rapid reduction of alloxan by thioredoxin in the presence of molecular oxygen and NADPH leads to strong chemiluminescence from luminol indicative of an intense radical protection. Luminol 127-134 thioredoxin 1 Mus musculus 30-41 7342976-5 1981 GSH, FeSO4 and luminol was inhibited by catalase, superoxide dismutase, scavengers of hydroxyl radicals (sodium benzoate, n-butanol, D-mannitol, dimethyl sulphoxide) or metal-ion chelators (EDTA, diethylenetriaminepenta-acetic acid, diethyldithiocarbamate. Luminol 15-22 catalase Homo sapiens 40-48 6270983-2 1981 Luminol chemiluminescence was inhibited by the addition of superoxide dismutase (SOD) and catalase. Luminol 0-7 superoxide dismutase 1 Homo sapiens 81-84 6780228-2 1980 Acetylcholine is hydrolysed by acetylcholinesterase; the choline liberated is oxidized by choline oxidase to betaine; the H2O2 generated triggers the luminescence of luminol in presence of peroxidase. Luminol 166-173 acetylcholinesterase (Cartwright blood group) Homo sapiens 31-51 7250311-0 1981 Effect of cholinesterase on the chemiluminescence of luminol. Luminol 53-60 butyrylcholinesterase Homo sapiens 10-24 7224588-1 1980 Within the first minute following their exposure to a specific anti-H-2 serum and in the absence of complement, murine spleen cells generate a chemiluminescence phenomenon which is precisely measurable by photometry in the presence of luminol. Luminol 235-242 histocompatibility-2, MHC Mus musculus 68-71 7407252-3 1980 The response is directly related to dose over a wide rane of luminol concentrations and can be inhibited by superoxide dismutase (90%), catalase (100%) and sodium azide (40%). Luminol 61-68 catalase Homo sapiens 136-144 6775351-1 1980 The luminol chemiluminescence associated with the reaction between vesicular gland microsomes and arachidonic acid was found to be inhibited by superoxide dismutase, catalase and hydroxyl radical scavengers. Luminol 4-11 catalase Ovis aries 166-174 34013434-3 2021 In this system, Co(OH)2 nanosheets act as nanozymes to catalyze and amplify the chemiluminescence signal of the luminol-PIP-H2O2 system, as well as a carrier for immobilizing antibodies to form stable immunoprobes. Luminol 112-119 prolactin induced protein Homo sapiens 120-123