PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 21800306-6 2012 However, 33% of PPG(+) neurons contain neurokinin-1 receptor (NK1R) in the rVRG (126 +- 12; n = 12), accounting for ~28% of all NK1R(+) neurons in the region. ppg 16-19 tachykinin receptor 1 Rattus norvegicus 39-60 21800306-6 2012 However, 33% of PPG(+) neurons contain neurokinin-1 receptor (NK1R) in the rVRG (126 +- 12; n = 12), accounting for ~28% of all NK1R(+) neurons in the region. ppg 16-19 tachykinin receptor 1 Rattus norvegicus 62-66 21651690-7 2011 The GLP-1 group was associated with a greater reduction in PPG than the insulin group. ppg 59-62 glucagon like peptide 1 receptor Homo sapiens 4-9 22870268-10 2012 CSE inhibition by PPG and BCA reduced this effect in aortas from rats but not from mice. ppg 18-21 cystathionine gamma-lyase Rattus norvegicus 0-3 21131483-7 2011 The dilation to L-cysteine was blocked by the CSE inhibitor d,l-propargylglycine (PPG, 10 mM) but was unaffected by the CBS inhibitor amino-oxyacetate (AOA, 1 mM). ppg 82-85 cystathionine gamma-lyase Sus scrofa 46-49 21830440-5 2011 RESULTS: Patients in the PPG-nCBP group had a higher body mass index than patients in the PPG-CBP group (23.9 vs. 22.3 kg/m2; p=0.004), as well as a longer operation time (249.3 vs. 227.0 min; p=0.010). ppg 25-28 nuclear cap binding protein subunit 1 Homo sapiens 29-33 21830440-5 2011 RESULTS: Patients in the PPG-nCBP group had a higher body mass index than patients in the PPG-CBP group (23.9 vs. 22.3 kg/m2; p=0.004), as well as a longer operation time (249.3 vs. 227.0 min; p=0.010). ppg 25-28 CREB binding protein Homo sapiens 30-33 20702417-7 2010 pPG-induced silkworm death was delayed by injecting melanization-inhibiting reagents (a serine protease inhibitor and 1-phenyl-2-thiourea), antioxidants (N-acetyl-l-cysteine, glutathione, and catalase), and a caspase inhibitor (Ac-DEVD-CHO). ppg 0-3 catalase Bombyx mori 192-200 22255218-6 2011 These preliminary results suggest that a PPG sensor may be a suitable method for evaluating the perfusion of free flap. ppg 41-44 arachidonate 5-lipoxygenase activating protein Homo sapiens 114-118 19766903-5 2009 The aim of this study was to determine a relationship between SUR-1 [exon 16 (-3C/T), exon 31 (Arg1273Arg; AGG-->AGA) and exon 33 (S1369A)] and KCNJ11 (E23K) polymorphisms and the following parameters of metabolic control in T2D: fasting plasma glucose (FPG), postprandial glucose (PPG) and HbA1c in Caucasian T2D of European origin. ppg 285-288 ATP binding cassette subfamily C member 8 Homo sapiens 62-67 20142152-10 2010 These results suggest that the combination of DAP and PTTV could be better alternative for sleep apnea screening using PPG with the added benefit of its low cost and simplicity. ppg 119-122 death associated protein Homo sapiens 46-49 20088941-7 2010 Multiple regression analyses in the acarbose group revealed that PPG was the only significant predictor of 11-dehydro-TXB(2) urinary excretion rate (beta = 0.39, P = 0.002) and MAGE the only predictor of 8-iso-PGF(2alpha) urinary excretion rate (beta = 0.42, P = 0.001). ppg 65-68 placental growth factor Homo sapiens 210-213 21155215-15 2009 Pre-administration of PPG exacerbated the injuries induced by LPS, increased PMN and protein content in BALF, the plasma NO level, lung iNOS activity and its protein expression, but there was no prominent variation in CO level, HO activity and HO-1 protein expression compared with those of LPS group. ppg 22-25 nitric oxide synthase 2 Rattus norvegicus 136-140 21155215-15 2009 Pre-administration of PPG exacerbated the injuries induced by LPS, increased PMN and protein content in BALF, the plasma NO level, lung iNOS activity and its protein expression, but there was no prominent variation in CO level, HO activity and HO-1 protein expression compared with those of LPS group. ppg 22-25 heme oxygenase 1 Rattus norvegicus 244-248 19369363-7 2009 Furthermore, the selective mGluR4 agonist ACPT-III and mGluR8 agonist PPG were effective at reducing the field potential, whereas agonists selective for mGluR6 and 7 were not. ppg 70-73 glutamate receptor, ionotropic, AMPA4 (alpha 4) Mus musculus 27-33 19369363-7 2009 Furthermore, the selective mGluR4 agonist ACPT-III and mGluR8 agonist PPG were effective at reducing the field potential, whereas agonists selective for mGluR6 and 7 were not. ppg 70-73 glutamate receptor, metabotropic 8 Mus musculus 55-61 19077774-4 2009 Several antidiabetic agents that specifically target PPG are currently available, including glinides, glucagon-like peptide-1 mimetics, dipeptidyl peptidase-4 inhibitors, and rapid-acting insulin analogs. ppg 53-56 glucagon Homo sapiens 102-125 19234054-9 2009 However, pulmonary artery MMP-13 and TIMP-1 expressions decreased significantly in rats of shunt+PPG group (P<0.01). ppg 97-100 matrix metallopeptidase 13 Rattus norvegicus 26-32 19234054-9 2009 However, pulmonary artery MMP-13 and TIMP-1 expressions decreased significantly in rats of shunt+PPG group (P<0.01). ppg 97-100 TIMP metallopeptidase inhibitor 1 Rattus norvegicus 37-43 19077774-4 2009 Several antidiabetic agents that specifically target PPG are currently available, including glinides, glucagon-like peptide-1 mimetics, dipeptidyl peptidase-4 inhibitors, and rapid-acting insulin analogs. ppg 53-56 dipeptidyl peptidase 4 Homo sapiens 136-158 18558402-7 2008 Additionally, the effect of PPG on reactive oxygen species (ROS) production and induction of IL-10, IL-12 and IFN-gamma secretion by human peripheral blood mononuclear cells (PBMCs) isolated from healthy individuals was investigated. ppg 28-31 interleukin 10 Homo sapiens 93-98 18558402-7 2008 Additionally, the effect of PPG on reactive oxygen species (ROS) production and induction of IL-10, IL-12 and IFN-gamma secretion by human peripheral blood mononuclear cells (PBMCs) isolated from healthy individuals was investigated. ppg 28-31 interferon gamma Homo sapiens 110-119 18558402-8 2008 The water-soluble secreted form of PPG at a concentration of 1 microg glycan/ml seems to be a potent inducer of ROS and IL-10 and to a lesser extent of IFN-gamma and IL-12. ppg 35-38 interleukin 10 Homo sapiens 120-125 18558402-8 2008 The water-soluble secreted form of PPG at a concentration of 1 microg glycan/ml seems to be a potent inducer of ROS and IL-10 and to a lesser extent of IFN-gamma and IL-12. ppg 35-38 interferon gamma Homo sapiens 152-161 18248901-8 2008 Furthermore, PPG pretreatment attenuated the induction of c-Fos in spinal laminae I-II following injection of 5% formalin. ppg 13-16 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 58-63 16919548-2 2006 After a meal, the rise in postprandial glucose (PPG) is controlled by the rapid pancreatic release of insulin, stimulated by both glucose and the intestinal production of the incretins glucose-dependent insulinotropic polypeptide and glucagon-like peptide 1. ppg 48-51 insulin Homo sapiens 102-109 18667139-5 2007 Subsequently, a progressive loss of first-phase insulin response occurs, which is manifested by progressively increasing postprandial glucose (PPG) levels. ppg 143-146 insulin Homo sapiens 48-55 17375403-3 2006 Alpha-glucosidase inhibitors can reduce PPG by a mean 0.50 g/l, no matter what the insulin resistance or insulinopenia status or the other diabetes treatments already in use. ppg 40-43 sucrase-isomaltase Homo sapiens 0-17 16919548-2 2006 After a meal, the rise in postprandial glucose (PPG) is controlled by the rapid pancreatic release of insulin, stimulated by both glucose and the intestinal production of the incretins glucose-dependent insulinotropic polypeptide and glucagon-like peptide 1. ppg 48-51 glucagon Homo sapiens 234-257 16919548-11 2006 The development of glucagon-like peptide 1 agonists such as exendin and dipeptidyl peptidase IV inhibitors such as vildagliptin offers a new approach to suppression of PPG elevation. ppg 168-171 glucagon Homo sapiens 19-42 16526817-8 2006 Treating PPG with glinides improves IMT as well as interleukin-6 and C-reactive protein levels, while treating PPG with rapid-acting insulin analogues is also associated with improvements in endothelial dysfunction. ppg 9-12 interleukin 6 Homo sapiens 51-64 16526817-8 2006 Treating PPG with glinides improves IMT as well as interleukin-6 and C-reactive protein levels, while treating PPG with rapid-acting insulin analogues is also associated with improvements in endothelial dysfunction. ppg 9-12 C-reactive protein Homo sapiens 69-87 16526817-8 2006 Treating PPG with glinides improves IMT as well as interleukin-6 and C-reactive protein levels, while treating PPG with rapid-acting insulin analogues is also associated with improvements in endothelial dysfunction. ppg 111-114 insulin Homo sapiens 133-140 16000308-3 2005 The phage display-derived recognition motif for CD2BP2-GYF is PPG(W/F/Y/M/L). ppg 62-65 CD2 cytoplasmic tail binding protein 2 Homo sapiens 48-54 14970889-4 2004 Meanwhile, the activities of CSE in pulmonary tissue in hypoxic, hypoxic + L-NAME and control groups were detected, respectively, and expressions of NOS in pulmonary arteries in hypoxic, hypoxic + PPG and control groups were also detected by immunohistochemistry technique. ppg 197-200 cystathionine gamma-lyase Rattus norvegicus 29-32 16145866-9 2005 Only marginally statistically significant influence of p53 expression was found on patient survival between MPG and PPG. ppg 116-119 tumor protein p53 Homo sapiens 55-58 14606987-8 2003 The insulin sensitizer metformin, on the other hand, does not affect PPG levels, whereas the alpha-glucosidase inhibitors, in the presence of a high-carbohydrate diet, can effectively lower PPG. ppg 190-193 sucrase-isomaltase Homo sapiens 93-110 12689550-9 2003 In DM2 patients, a bad control was observed in 82.1% (CI 95%, 77.9-86.3) of them according to BG, in 88.4% (85.1-91.7) according to PPG and in 18.8% (14.3-23.3) according to A1C. ppg 132-135 immunoglobulin heavy diversity 1-14 (non-functional) Homo sapiens 3-6 12376193-5 2002 For example, AIDA (50 mM; mGLUR(1) antagonist) blocked the effects of EC(50) concentrations of 3,5-DHPG, and PPG. ppg 109-112 axin interactor, dorsalization associated Rattus norvegicus 13-17 12376193-5 2002 For example, AIDA (50 mM; mGLUR(1) antagonist) blocked the effects of EC(50) concentrations of 3,5-DHPG, and PPG. ppg 109-112 glutamate receptor, ionotropic, AMPA1 (alpha 1) Mus musculus 26-34 12376193-8 2002 CPPG (80 mM) and MSOP (125 mM), mGLUR(4) antagonists, blocked the effects of 3,5-DHPG, PPG and L-AP(4.) ppg 1-4 glutamate receptor, ionotropic, AMPA4 (alpha 4) Mus musculus 32-40 9293701-4 1997 The smallest (0.15 micron diameter) PPG was the least dense granule, had a unique peroxidase/beta-glucuronidase ratio, reacted intensely for vicinal glycols, resisted ionophore degranulation and was not consumed in giant granule formation in Chediak-Higashi Syndrome. ppg 36-39 glucuronidase beta Homo sapiens 93-111 11198928-3 2000 Phosphodiester pyrrazolopyrimidine dG (PPG)-modified TFO complementary to the polypurine-polypyrimidine region of the mdr1 gene were synthesized and labeled with 125I-dCTP at the C5 position of two cytosines by the primer extension method. ppg 39-42 ATP binding cassette subfamily B member 1 Homo sapiens 118-122 10378794-2 1999 In this study, we undertook to clarify the relationship between P-glycoprotein positivity (%PPG) and doxorubicin binding ability (%DB) in human osteosarcomas in order to determine which is a more sensitive index of histologic response to chemotherapy. ppg 92-95 ATP binding cassette subfamily B member 1 Homo sapiens 64-78 11374906-3 2001 Unlike Esx1, ESXR1 contains 12 repeats of a unique nine amino acid motif, PPMAP(V/L)PPG, located C-terminal to the homeodomain. ppg 84-87 ESX homeobox 1 Homo sapiens 13-18 34772419-6 2021 RESULTS: After nateglinide treatment for 8 consecutive weeks, patients with at least one C allele of PPARD rs2016520 showed a smaller decrease in post plasma glucose (PPG), homeostasis model assessment for beta cell function (HOMA-B) than those with the TT genotype did (P < 0.05). ppg 167-170 peroxisome proliferator activated receptor delta Homo sapiens 101-106 1306602-8 1992 The fasting and postprandial serum gastrin levels were high in one patient with recurrence, whose antrum was preserved as long as 3 cm proximal to the pyloric ring; this was longer than that described in our original method of PPG. ppg 227-230 gastrin Homo sapiens 35-42 33776458-8 2021 Conclusion: The analysis indicates that the supplementation of BOT with a single daily injection of prandial insulin is safe and effective for reducing HbA1c and PPG levels in patients with a high BeAM value (more than 50 mg/dl). ppg 162-165 insulin Homo sapiens 109-116 34779492-9 2022 PPG (a CSE inhibitor) abolished the beneficial effects of SKF38393. ppg 0-3 cystathionase (cystathionine gamma-lyase) Mus musculus 7-10 34220720-10 2021 In both groups, the reduction in PPG was accompanied by a two-three-fold increase in GLP-1 and delayed gastric emptying. ppg 33-36 glucagon Homo sapiens 85-90 34220720-14 2021 Conclusion: Pre-meal ingestion of a novel, ready-to-drink WP shot containing just 15 g of dietary protein reduced PPG in lean and centrally obese males. ppg 114-117 short stature homeobox 2 Homo sapiens 61-65 34220720-15 2021 However, an attenuated GLP-1 response to mealtime WP and increased incretin degradation might impact the efficacy of nutritional strategies utilising the actions of GLP-1 to regulate PPG in centrally obese populations. ppg 183-186 glucagon Homo sapiens 23-28 34220720-15 2021 However, an attenuated GLP-1 response to mealtime WP and increased incretin degradation might impact the efficacy of nutritional strategies utilising the actions of GLP-1 to regulate PPG in centrally obese populations. ppg 183-186 glucagon Homo sapiens 165-170 35598134-8 2022 About 73.5% of the respondents believed controlling fasting plasma glucose (FPG) level alone would not adequately control postprandial plasma glucose (PPG) level, and 93.0% of them preferred an insulin therapy at the initiation that controls both FPG and PPG levels. ppg 255-258 insulin Homo sapiens 194-201 34150441-3 2021 The aim of this study was to define the differences in the efficacy of these two insulin analogues on PPG. ppg 102-105 insulin Homo sapiens 81-88 35593434-8 2022 Indeed, in pivotal phase 3 trials, URLi was superior to Lispro for PPG control both at 1 hour and 2 hours after a meal in type 1 and type 2 diabetes with multiple daily injections and in type 1 diabetes with continuous subcutaneous insulin infusion. ppg 67-70 insulin Homo sapiens 232-239 35598134-9 2022 CONCLUSION: Limited consultation time, high-carbohydrate diet, and a need for choosing insulin regimens that provide control for both PPG and FPG levels are some ground realities of DM management in India. ppg 134-137 insulin Homo sapiens 87-94 35226992-17 2022 PPG (a CSE inhibitor) abolished the beneficial effect of SKF38393. ppg 0-3 cystathionine gamma-lyase Homo sapiens 7-10 35509763-2 2022 This study aims to compare the serum PRL levels between type 2 diabetes mellitus (T2DM) patients and normoglycaemic volunteers and correlate the serum PRL level with fasting plasma glucose (FPG), postprandial plasma glucose (PPG), glycated haemoglobin (HbA1c) levels, and the lipid profile in the study population. ppg 225-228 prolactin Homo sapiens 151-154 33460657-4 2021 Thioflavin-T (ThT) fluorescence assays showed that the binding of EA or PPG could effectively inhibit the nucleation and elongation of PrP fibrilization and reduce the amount of PrP fibrils generated. ppg 72-75 prion protein Homo sapiens 135-138 35044568-2 2022 The aim of this study was to compare PPG increments in Asian versus non-Asian adults with type 2 diabetes (T2D), who were insulin-naive or insulin-experienced, from the phase 3 insulin degludec/insulin aspart (IDegAsp) clinical trials. ppg 37-40 insulin Homo sapiens 122-129 35044568-2 2022 The aim of this study was to compare PPG increments in Asian versus non-Asian adults with type 2 diabetes (T2D), who were insulin-naive or insulin-experienced, from the phase 3 insulin degludec/insulin aspart (IDegAsp) clinical trials. ppg 37-40 insulin Homo sapiens 139-146 35044568-2 2022 The aim of this study was to compare PPG increments in Asian versus non-Asian adults with type 2 diabetes (T2D), who were insulin-naive or insulin-experienced, from the phase 3 insulin degludec/insulin aspart (IDegAsp) clinical trials. ppg 37-40 insulin Homo sapiens 177-184 35044568-2 2022 The aim of this study was to compare PPG increments in Asian versus non-Asian adults with type 2 diabetes (T2D), who were insulin-naive or insulin-experienced, from the phase 3 insulin degludec/insulin aspart (IDegAsp) clinical trials. ppg 37-40 insulin Homo sapiens 194-201 33730337-1 2021 INTRODUCTION: Basal-bolus (BB) and premixed insulin regimens may lower fasting plasma glucose (FPG) and postprandial plasma glucose (PPG), but are complex to use and associated with weight gain and hypoglycaemia. ppg 133-136 insulin Homo sapiens 44-51 33658478-2 2021 We performed a systematic review and meta-analysis to quantify effects of alpha-glucosidase-inhibiting (AGI) drugs on acute PPG and PPI responses. ppg 124-127 sucrase-isomaltase Homo sapiens 74-91 33460657-4 2021 Thioflavin-T (ThT) fluorescence assays showed that the binding of EA or PPG could effectively inhibit the nucleation and elongation of PrP fibrilization and reduce the amount of PrP fibrils generated. ppg 72-75 prion protein Homo sapiens 178-181 33460657-6 2021 Circular dichroism (CD) measurements suggested that EA- or PPG-bound PrP could preserve a higher content of alpha-helical structures than beta-sheet-rich PrP fibrils. ppg 59-62 prion protein Homo sapiens 69-72 33644113-11 2020 The membrane translocation of nPKCdelta and the expression of VCAM-1 in UAAS group was higher than sham group, L-cys or NaHS injection could suppress the membrane translocation of nPKCdelta and the expression of VCAM-1, but PPG treatment resulted in more membrane translocation of nPKCdelta and the expression of VCAM-1 (P<0.05, n=6 per group). ppg 224-227 protein kinase C delta Homo sapiens 30-39 33644113-11 2020 The membrane translocation of nPKCdelta and the expression of VCAM-1 in UAAS group was higher than sham group, L-cys or NaHS injection could suppress the membrane translocation of nPKCdelta and the expression of VCAM-1, but PPG treatment resulted in more membrane translocation of nPKCdelta and the expression of VCAM-1 (P<0.05, n=6 per group). ppg 224-227 vascular cell adhesion molecule 1 Homo sapiens 212-218 33644113-11 2020 The membrane translocation of nPKCdelta and the expression of VCAM-1 in UAAS group was higher than sham group, L-cys or NaHS injection could suppress the membrane translocation of nPKCdelta and the expression of VCAM-1, but PPG treatment resulted in more membrane translocation of nPKCdelta and the expression of VCAM-1 (P<0.05, n=6 per group). ppg 224-227 vascular cell adhesion molecule 1 Homo sapiens 212-218 33644113-12 2020 Akt phosphorylation in UAAS group was lower than sham group, and L-cys or NaHS injection could suppress the degradation of Akt phosphorylation, but PPG treatment resulted in more decrease in the Akt phosphorylation (P<0.05, n=6 per group). ppg 148-151 AKT serine/threonine kinase 1 Homo sapiens 0-3 33644113-12 2020 Akt phosphorylation in UAAS group was lower than sham group, and L-cys or NaHS injection could suppress the degradation of Akt phosphorylation, but PPG treatment resulted in more decrease in the Akt phosphorylation (P<0.05, n=6 per group). ppg 148-151 AKT serine/threonine kinase 1 Homo sapiens 123-126 33644113-12 2020 Akt phosphorylation in UAAS group was lower than sham group, and L-cys or NaHS injection could suppress the degradation of Akt phosphorylation, but PPG treatment resulted in more decrease in the Akt phosphorylation (P<0.05, n=6 per group). ppg 148-151 AKT serine/threonine kinase 1 Homo sapiens 123-126 32277270-11 2021 Changes in acute PPG were significantly associated with changes in fasting plasma glucose (FPG) [per 10% change in PPG: beta = 0.085 (95% CI 0.003, 0.167), k = 14], but not with fasting insulin [beta = 1.20 (95% CI - 0.32, 2.71), k = 12]. ppg 17-20 insulin Homo sapiens 186-193 32436323-6 2020 Recently, fixed-ratio combinations (FRCs) of BI and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have shown efficacy in reducing both FPG and PPG with a single injection and without increased risk of hypoglycaemia or weight gain. ppg 151-154 glucagon like peptide 1 receptor Homo sapiens 52-84 32641052-7 2020 However, PPG had the benefits of lower incidence of anastomosis leakage, early dumping syndrome, gastritis and bile reflux, and better recovery of total protein, albumin, hemoglobin, and weight. ppg 9-12 albumin Homo sapiens 162-169 33786271-1 2021 Background: In general, basal insulin targets fasting plasma glucose (FPG) levels, and prandial insulin targets postprandial glucose (PPG) levels. ppg 134-137 insulin Homo sapiens 96-103 33786271-2 2021 However, the effects of basal insulin on PPG levels are controversial. ppg 41-44 insulin Homo sapiens 30-37 33318871-8 2021 PPG inhibited expression of PPARdelta and SOCS3, stimulated the phosphorylation of STAT3, increased inflammatory molecules production and proliferation rate of VSMCs which could all be corrected by NaHS supply. ppg 0-3 peroxisome proliferator activator receptor delta Mus musculus 28-37 33318871-8 2021 PPG inhibited expression of PPARdelta and SOCS3, stimulated the phosphorylation of STAT3, increased inflammatory molecules production and proliferation rate of VSMCs which could all be corrected by NaHS supply. ppg 0-3 suppressor of cytokine signaling 3 Mus musculus 42-47 33318871-8 2021 PPG inhibited expression of PPARdelta and SOCS3, stimulated the phosphorylation of STAT3, increased inflammatory molecules production and proliferation rate of VSMCs which could all be corrected by NaHS supply. ppg 0-3 signal transducer and activator of transcription 3 Mus musculus 83-88 30036087-4 2019 Inhibition of both cystathionine-gamma-lyase (CSE) and cystathionine-beta-synthase (CBS), 2 major enzymes for endogenous H2S production, with propargylglycine (PPG) and amino-oxyacetate (AOAA), respectively, caused increased urine output and reduced urine osmolality in mice that was associated with decreased expression of aquaporin (AQP)-2 in the renal inner medulla. ppg 160-163 cystathionase (cystathionine gamma-lyase) Mus musculus 19-44 31963730-4 2020 A PARP-1 enzyme inhibition assay and PARylation experiment showed that the inhibitory activity of the prodrug was reduced 380 times and more than 658 times, respectively, which proved that the prodrug"s expected activity was lost after PPG protection. ppg 236-239 poly(ADP-ribose) polymerase 1 Homo sapiens 2-8 31226281-3 2019 OBJECTIVES: To evaluate how often patients on insulin therapy measure PPG and modify insulin doses accordantly. ppg 70-73 insulin Homo sapiens 46-53 30466191-4 2019 RESULTS: A statistically significant treatment difference in favour of fast-acting insulin aspart vs. insulin aspart was observed for the change in PPG increment at all post-meal time points (from 1 to 4 h) for those in the > 20 units bolus insulin subgroup. ppg 148-151 insulin Homo sapiens 83-90 30466191-4 2019 RESULTS: A statistically significant treatment difference in favour of fast-acting insulin aspart vs. insulin aspart was observed for the change in PPG increment at all post-meal time points (from 1 to 4 h) for those in the > 20 units bolus insulin subgroup. ppg 148-151 insulin Homo sapiens 102-109 30466191-4 2019 RESULTS: A statistically significant treatment difference in favour of fast-acting insulin aspart vs. insulin aspart was observed for the change in PPG increment at all post-meal time points (from 1 to 4 h) for those in the > 20 units bolus insulin subgroup. ppg 148-151 insulin Homo sapiens 102-109 30466191-6 2019 CONCLUSION: Fast-acting insulin aspart may hold promise as a more effective treatment compared with insulin aspart for controlling PPG in people with insulin-resistant Type 2 diabetes. ppg 131-134 insulin Homo sapiens 24-31 30036087-4 2019 Inhibition of both cystathionine-gamma-lyase (CSE) and cystathionine-beta-synthase (CBS), 2 major enzymes for endogenous H2S production, with propargylglycine (PPG) and amino-oxyacetate (AOAA), respectively, caused increased urine output and reduced urine osmolality in mice that was associated with decreased expression of aquaporin (AQP)-2 in the renal inner medulla. ppg 160-163 cystathionase (cystathionine gamma-lyase) Mus musculus 46-49 30036087-4 2019 Inhibition of both cystathionine-gamma-lyase (CSE) and cystathionine-beta-synthase (CBS), 2 major enzymes for endogenous H2S production, with propargylglycine (PPG) and amino-oxyacetate (AOAA), respectively, caused increased urine output and reduced urine osmolality in mice that was associated with decreased expression of aquaporin (AQP)-2 in the renal inner medulla. ppg 160-163 cystathionine beta-synthase Mus musculus 55-82 30036087-4 2019 Inhibition of both cystathionine-gamma-lyase (CSE) and cystathionine-beta-synthase (CBS), 2 major enzymes for endogenous H2S production, with propargylglycine (PPG) and amino-oxyacetate (AOAA), respectively, caused increased urine output and reduced urine osmolality in mice that was associated with decreased expression of aquaporin (AQP)-2 in the renal inner medulla. ppg 160-163 cystathionine beta-synthase Mus musculus 84-87 30036087-5 2019 Mice treated with both PPG and AOAA developed a urine concentration defect in response to dehydration that was accompanied by reduced AQP-2 protein expression. ppg 23-26 aquaporin 2 Mus musculus 134-139 32142871-7 2020 And the results showed that more pPG-612-AHA1-CK6-VP2/L. ppg 33-36 activator of HSP90 ATPase activity 1 Homo sapiens 41-45 32821480-9 2020 The ability to diagnose PPG using these GCL/IPL parameters was statistically higher than for total or superior and inferior hemiretinal GCL/IPL thicknesses. ppg 24-27 germ cell-less 2, spermatogenesis associated Homo sapiens 40-43 32821480-9 2020 The ability to diagnose PPG using these GCL/IPL parameters was statistically higher than for total or superior and inferior hemiretinal GCL/IPL thicknesses. ppg 24-27 pleckstrin homology like domain family A member 2 Homo sapiens 44-47 29493118-1 2018 AIM: To investigate the mechanisms behind the lower postprandial glucose (PPG) concentrations achieved with fast-acting insulin aspart (faster aspart) than with insulin aspart (IAsp). ppg 74-77 insulin Homo sapiens 161-168 30058059-9 2018 The treatment factors influencing the choice of a DPP-4 inhibitor were glycated hemoglobin (HbA1c) and postprandial glucose (PPG) lowering effect, frequency of administration, effect on glucagon, and ease of use in patients with renal or liver impairment. ppg 125-128 dipeptidyl peptidase 4 Homo sapiens 50-55 30058059-11 2018 The patient characteristics for the choice of DPP-4 inhibitors among diabetologists were predominantly PPG, concern about hypoglycemia, diabetes complications, and adherence to diet and exercise. ppg 103-106 dipeptidyl peptidase 4 Homo sapiens 46-51 29696567-10 2018 The key patient characteristics driving the choice of DPP-4is or metformin as the first-line OAD by physicians were similar to those that influenced the treatment intensification decision (DPP-4is: PPG and renal function; metformin: age, BMI, insulin resistance, and renal function). ppg 198-201 dipeptidyl peptidase 4 Homo sapiens 189-194 29916741-4 2018 Thus, a dual SGLT1 and SGLT2 inhibition (compared with selective SGLT2 inhibition) could result in lower PPG and robust A1c reduction even in patients with reduced kidney function. ppg 105-108 solute carrier family 5 member 1 Homo sapiens 13-18 29916741-4 2018 Thus, a dual SGLT1 and SGLT2 inhibition (compared with selective SGLT2 inhibition) could result in lower PPG and robust A1c reduction even in patients with reduced kidney function. ppg 105-108 solute carrier family 5 member 2 Homo sapiens 23-28 29916741-4 2018 Thus, a dual SGLT1 and SGLT2 inhibition (compared with selective SGLT2 inhibition) could result in lower PPG and robust A1c reduction even in patients with reduced kidney function. ppg 105-108 solute carrier family 5 member 2 Homo sapiens 65-70 29319536-6 2018 The best estimation model based on the combination of PPG and PPT could achieve a decrease (GAM & GSD) of 0.81 +- 0.95 mmHg in SBP and 0.75 +- 0.54 mmHg in DBP in comparison to the PPT-based methods. ppg 54-57 tachykinin precursor 1 Homo sapiens 189-192 29493118-1 2018 AIM: To investigate the mechanisms behind the lower postprandial glucose (PPG) concentrations achieved with fast-acting insulin aspart (faster aspart) than with insulin aspart (IAsp). ppg 74-77 insulin Homo sapiens 120-127 29955237-7 2018 CSE inhibitor PPG drastically inhibited TFR-evoked vasodilatation resistant to L-NAME and Indo in endothelium-intact rat CBA. ppg 14-17 transferrin receptor Rattus norvegicus 40-43 28408352-11 2017 These results suggest that Hdh-GnRH mRNA expression profiles in the BG and possibly the PPG are tightly correlated with abalone reproductive activities. ppg 88-91 gonadotropin releasing hormone 1 Homo sapiens 31-35 28117542-13 2017 CONCLUSION: Applying an additional dose of insulin in dual wave bolus for high-protein mixed meal improved PPG. ppg 107-110 insulin Homo sapiens 43-50 27986406-12 2017 CONCLUSIONS: Lixisenatide in combination with basal insulin was shown to be an effective treatment strategy for patients with type 2 diabetes, controlling HbA1c levels by reduction of PPG excursions during the whole day. ppg 184-187 insulin Homo sapiens 52-59 29032696-6 2017 Appropriately timed exposure of the liver to insulin is critical in suppressing hepatic glucose output (and therefore PPG levels) after a meal. ppg 118-121 insulin Homo sapiens 45-52 26413295-13 2015 In all the studies that estimated the relative contribution FPG and PPG to the overall hyperglycemia, decreases in PPG was accounted for greater decrease in HbA1c compared with decreases in FPG value. ppg 115-118 hemoglobin subunit alpha 1 Homo sapiens 157-161 26827116-10 2016 For exenatide BID, reductions in PPG excursions for all meals were significantly greater in Asians (P<0.0001 vs Whites), whereas only post-breakfast and post-lunch excursions were significantly greater in Asians for exenatide QW (P=0.0009 and P=0.0189 vs Whites, respectively). ppg 33-36 BH3 interacting domain death agonist Homo sapiens 14-17 26827116-12 2016 CONCLUSIONS: Exenatide BID and QW improved glycemic control, including PPG, in Asian and White patients with T2DM. ppg 71-74 BH3 interacting domain death agonist Homo sapiens 23-26 26827116-13 2016 With exenatide BID, Asian patients exhibited significantly greater reductions in HbA1c and PPG than White patients. ppg 91-94 BH3 interacting domain death agonist Homo sapiens 15-18 27043162-5 2016 The goal of this review is to summarize the effects of albiglutide on PPG in four phase 2 trials and to describe the PPG-lowering effects of the GLP-1 RAs. ppg 117-120 glucagon like peptide 1 receptor Homo sapiens 145-150 27136525-2 2016 Highly potent VEGFR-2 inhibitors 1 and 3 were caged by introduction of a photoremovable protecting group (PPG) to yield the caged prodrugs 4 and 5. ppg 106-109 kinase insert domain receptor Homo sapiens 14-21 24793048-6 2015 Pre-incubation with the cystathionine gamma-lyase inhibitor, D,L-propargylglycine (PPG), resulted in a paradoxical augmentation of shear stress-mediated vasodilation. ppg 83-86 cystathionase (cystathionine gamma-lyase) Mus musculus 24-49 25945746-8 2015 PPG decreased creatinine, H2S, IL-10, and TNF-alpha levels, but this effect was reversed by NaHS administration. ppg 0-3 interleukin 10 Rattus norvegicus 26-36 25945746-8 2015 PPG decreased creatinine, H2S, IL-10, and TNF-alpha levels, but this effect was reversed by NaHS administration. ppg 0-3 tumor necrosis factor Rattus norvegicus 42-51 28239260-2 2015 In this work, the extraction ability for bovine serum albumin (BSA) of aqueous biphasic systems (ABS) formed by polypropylene glycol 400 (PPG 400) and several GB-ILs was evaluated. ppg 138-141 albumin Homo sapiens 48-61 26053860-3 2015 Identification and specific labeling of PPG was achieved through cell type-specific RNAi-mediated knockdown (KD) of a glial marker, Glutamine Synthetase 2 (GS2). ppg 40-43 Glutamine synthetase 2 Drosophila melanogaster 132-154 26053860-3 2015 Identification and specific labeling of PPG was achieved through cell type-specific RNAi-mediated knockdown (KD) of a glial marker, Glutamine Synthetase 2 (GS2). ppg 40-43 Glutamine synthetase 2 Drosophila melanogaster 156-159 25881041-10 2015 In addition, both MMPIP and PPG acted as inverse agonists at mGluR7, and agonists at mGluR8. ppg 28-31 glutamate receptor, ionotropic, kainate 3 Mus musculus 61-67 25881041-10 2015 In addition, both MMPIP and PPG acted as inverse agonists at mGluR7, and agonists at mGluR8. ppg 28-31 glutamate receptor, metabotropic 8 Mus musculus 85-91 25066229-2 2015 The relative contribution of postprandial plasma glucose (PPG) to overall HbA1c is estimated at 40-60%, with the effect of PPG on HbA1c being prominent in patients on basal insulin. ppg 58-61 hemoglobin subunit alpha 1 Homo sapiens 74-78 25066229-2 2015 The relative contribution of postprandial plasma glucose (PPG) to overall HbA1c is estimated at 40-60%, with the effect of PPG on HbA1c being prominent in patients on basal insulin. ppg 123-126 insulin Homo sapiens 173-180 26428031-5 2015 Prandial GLP-1 RAs have a short plasma half-life and are particularly effective at targeting PPG elevations, whereas long-acting non-prandial GLP-1 RAs are more effective at reducing fasting plasma glucose. ppg 93-96 glucagon like peptide 1 receptor Homo sapiens 9-14 25050128-2 2014 TFR (11~2700 mg/L) evoked dose-dependent vasodilation and hyperpolarization in MCA of both sham and CIR that were partially inhibited by 30 muM N-nitro-L-arginine-methyl-ester and 10 muM indomethacin and further attenuated by endogenous H2S synthese-CSE inhibitor PPG (100 muM) or Ca(2+)-activated potassium channel (Kca) inhibitor TEA (1 mM). ppg 264-267 transferrin receptor Rattus norvegicus 0-3 24641271-2 2014 This meta-analysis aimed to investigate the effects of the once-daily prandial GLP-1 receptor agonist lixisenatide on postprandial plasma glucose (PPG), glucagon and insulin levels. ppg 147-150 glucagon like peptide 1 receptor Homo sapiens 79-93 24926379-7 2014 The combination therapy of vildagliptin plus an alpha-glucosidase inhibitor effectively reduced the FBG, PPG and HbA1c levels in patients without inducing weight gain or hepatorenal dysfunction. ppg 105-108 sucrase-isomaltase Homo sapiens 48-65 23992745-2 2014 GLP-1 delays gastric emptying, which is vital for postprandial glucose (PPG) control. ppg 72-75 glucagon Homo sapiens 0-5 29922357-5 2013 Glucagon-like peptide 1 (GLP-1) receptor agonists have shown substantial efficacy in improving overall glycaemic control but have differing effects on PPG, which is a result of their different mechanisms of action. ppg 151-154 glucagon Homo sapiens 0-23 24147558-4 2013 In patients with moderate hyperglycemia, PPG excursions have a greater contribution to overall hyperglycemia, with this contribution being greatest when HbA1c is approximately 7-8% [1] . ppg 41-44 hemoglobin subunit alpha 1 Homo sapiens 153-157 29922357-5 2013 Glucagon-like peptide 1 (GLP-1) receptor agonists have shown substantial efficacy in improving overall glycaemic control but have differing effects on PPG, which is a result of their different mechanisms of action. ppg 151-154 glucagon like peptide 1 receptor Homo sapiens 25-40 23864951-7 2013 Interestingly, inhibiting endogenous, CSE-dependent H2S production with PPG did not exacerbate the deleterious vascular changes seen in the untreated fat-fed ApoE(-/-) mice. ppg 72-75 cystathionase (cystathionine gamma-lyase) Mus musculus 38-41 23448112-4 2013 However, evidence supporting the cost-effectiveness of PPG-CSF is inconclusive, and American Society of Clinical Oncology guidelines state the need for performing cost analyses in high-risk groups like the elderly. ppg 55-58 colony stimulating factor 2 Homo sapiens 59-62 23448112-5 2013 OBJECTIVES: To examine the effect of PPG-CSF administration on neutropenia hospitalization costs and overall Medicare costs during the year following chemotherapy initiation. ppg 37-40 colony stimulating factor 2 Homo sapiens 41-44 23448112-10 2013 CONCLUSIONS: A significant part of the increase in immediate medical costs in breast cancer patients receiving PPG-CSF is due to improved chemotherapy administration. ppg 111-114 colony stimulating factor 2 Homo sapiens 115-118 23527297-7 2013 Furthermore, the enhanced therapeutic efficacy of PPG could be correlated with effective silencing of miR-21 and with increased accumulation of ADR in drug-resistant tumor cells. ppg 50-53 microRNA 21 Homo sapiens 102-108 22836490-6 2012 Lastly, SgI(O) ([mg/dl]/min) was calculated as [PPG-without insulin and Sg]-[PPG-without insulin / with Sg] x [(2hPG) / 2hPG(E)]. ppg 48-51 semenogelin 1 Homo sapiens 8-11 22836490-6 2012 Lastly, SgI(O) ([mg/dl]/min) was calculated as [PPG-without insulin and Sg]-[PPG-without insulin / with Sg] x [(2hPG) / 2hPG(E)]. ppg 77-80 semenogelin 1 Homo sapiens 8-11 22436069-8 2012 At lower/near normal HbA(1C) , a short-acting GLP-1 RA, such as exenatide twice-daily, may be a better choice as its effects are more pronounced with PPG. ppg 150-153 glucagon like peptide 1 receptor Homo sapiens 46-51 22074719-7 2012 Both aspartate, which inhibits the 3-MST synthesis pathway, and propargylglycine (PPG), which inhibits the CSE pathway, significantly reduced the increases in arterial pressure during hypoxia. ppg 82-85 cystathionine gamma-lyase Rattus norvegicus 107-110