PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 24309939-0 2013 Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells, and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway. wentilactone 0-12 HRas proto-oncogene, GTPase Homo sapiens 136-140 24309939-0 2013 Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells, and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway. wentilactone 0-12 zinc fingers and homeoboxes 2 Homo sapiens 190-193 24309939-0 2013 Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells, and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway. wentilactone 0-12 mitogen-activated protein kinase 1 Homo sapiens 194-197 24309939-0 2013 Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells, and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway. wentilactone 0-12 tumor protein p53 Homo sapiens 198-201 24309939-0 2013 Wentilactone A as a novel potential antitumor agent induces apoptosis and G2/M arrest of human lung carcinoma cells, and is mediated by HRas-GTP accumulation to excessively activate the Ras/Raf/ERK/p53-p21 pathway. wentilactone 0-12 H3 histone pseudogene 16 Homo sapiens 202-205 22972522-4 2012 In addition, Wentilactone B could inhibit the metastasis of SMMC-7721 cells, which was detected by colony formation, scratch migration and a transwell assay, and could induce a series of intracellular events, including the down-regulation of CD44 and epidermal growth factor receptor proteins. wentilactone 13-25 CD44 molecule (Indian blood group) Homo sapiens 242-246