PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
19570892-7	2009	On the contrary, both maxiK blockers increased the responses elicited by dinitrophenol, a stimulus we demonstrate does not affect maxiK channels in isolated patches of rat chemoreceptor cells.	Dinitrophenols	73-86	potassium calcium-activated channel subfamily M alpha 1	Rattus norvegicus	22-27
18435821-7	2008	In contrast, the mitochondrial uncoupler dinitrophenol (DNP), which like insulin increases surface GLUT4, reduced GLUT4 (but not transferrin) internalization, an effect additive to that of depleting clathrin but not cholesterol.	Dinitrophenols	41-54	insulin	Homo sapiens	73-80
18435821-7	2008	In contrast, the mitochondrial uncoupler dinitrophenol (DNP), which like insulin increases surface GLUT4, reduced GLUT4 (but not transferrin) internalization, an effect additive to that of depleting clathrin but not cholesterol.	Dinitrophenols	41-54	solute carrier family 2 member 4	Homo sapiens	99-104
18435821-7	2008	In contrast, the mitochondrial uncoupler dinitrophenol (DNP), which like insulin increases surface GLUT4, reduced GLUT4 (but not transferrin) internalization, an effect additive to that of depleting clathrin but not cholesterol.	Dinitrophenols	41-54	solute carrier family 2 member 4	Homo sapiens	114-119
18435821-7	2008	In contrast, the mitochondrial uncoupler dinitrophenol (DNP), which like insulin increases surface GLUT4, reduced GLUT4 (but not transferrin) internalization, an effect additive to that of depleting clathrin but not cholesterol.	Dinitrophenols	41-54	transferrin	Homo sapiens	129-140
18435821-7	2008	In contrast, the mitochondrial uncoupler dinitrophenol (DNP), which like insulin increases surface GLUT4, reduced GLUT4 (but not transferrin) internalization, an effect additive to that of depleting clathrin but not cholesterol.	Dinitrophenols	56-59	insulin	Homo sapiens	73-80
18435821-7	2008	In contrast, the mitochondrial uncoupler dinitrophenol (DNP), which like insulin increases surface GLUT4, reduced GLUT4 (but not transferrin) internalization, an effect additive to that of depleting clathrin but not cholesterol.	Dinitrophenols	56-59	solute carrier family 2 member 4	Homo sapiens	99-104
18435821-7	2008	In contrast, the mitochondrial uncoupler dinitrophenol (DNP), which like insulin increases surface GLUT4, reduced GLUT4 (but not transferrin) internalization, an effect additive to that of depleting clathrin but not cholesterol.	Dinitrophenols	56-59	solute carrier family 2 member 4	Homo sapiens	114-119
18435821-8	2008	Trout GLUT4 (a natural variant of GLUT4 bearing different endocytic motifs) exogenously expressed in mammalian L6 cells internalized only through the cholesterol-dependent route that also included the non-clathrin-dependent cargo interleukin-2 receptor beta, and DNP reduced internalization of both proteins.	Dinitrophenols	263-266	solute carrier family 2 member 4	Homo sapiens	6-11
18187519-4	2008	DNP treatment of the human THP-1 macrophage cell line resulted in reduced ATP synthesis, and, although hyporesponsive to LPS, the metabolically stressed macrophages produced IL-1beta, IL-6, and TNF-alpha.	Dinitrophenols	0-3	GLI family zinc finger 2	Homo sapiens	27-32
18187519-4	2008	DNP treatment of the human THP-1 macrophage cell line resulted in reduced ATP synthesis, and, although hyporesponsive to LPS, the metabolically stressed macrophages produced IL-1beta, IL-6, and TNF-alpha.	Dinitrophenols	0-3	interleukin 1 beta	Homo sapiens	174-182
18187519-4	2008	DNP treatment of the human THP-1 macrophage cell line resulted in reduced ATP synthesis, and, although hyporesponsive to LPS, the metabolically stressed macrophages produced IL-1beta, IL-6, and TNF-alpha.	Dinitrophenols	0-3	interleukin 6	Homo sapiens	184-188
18187519-4	2008	DNP treatment of the human THP-1 macrophage cell line resulted in reduced ATP synthesis, and, although hyporesponsive to LPS, the metabolically stressed macrophages produced IL-1beta, IL-6, and TNF-alpha.	Dinitrophenols	0-3	tumor necrosis factor	Homo sapiens	194-203
15677757-0	2005	Adenosine 5"-monophosphate-activated protein kinase and p38 mitogen-activated protein kinase participate in the stimulation of glucose uptake by dinitrophenol in adult cardiomyocytes.	Dinitrophenols	145-158	mitogen activated protein kinase 14	Rattus norvegicus	56-59
16452722-5	2006	Embryonic development (cleavage and blastocyst stage) and the intracellular content of GSX were also decreased (P < or = 0.05) following exposure to DPI or DNP + DPI compared with control oocytes and oocytes from the other treatments.	Dinitrophenols	159-162	ATP binding cassette subfamily C member 1	Homo sapiens	87-90
17227964-0	2007	Ketone bodies alter dinitrophenol-induced glucose uptake through AMPK inhibition and oxidative stress generation in adult cardiomyocytes.	Dinitrophenols	20-33	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	65-69
12964759-7	2003	Lower levels of 0.19-1.4, 0.39-2.1, 0.053-0.55, and 0.081-0.10 microg/L were estimated for the corresponding C0-, C1-, C2-, and C3-dinitrophenols.	Dinitrophenols	131-145	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	109-130
12970384-3	2003	In RBL-2H3 mast cells sensitized with dinitrophenol (DNP)-specific IgE, the antigen exhibited several mast cell functions, including hexosaminidase release as a marker of degranulation, production of tumor necrosis factor-alpha, and production of immunologically detective leukotrienes.	Dinitrophenols	38-51	tumor necrosis factor	Rattus norvegicus	200-227
12970384-3	2003	In RBL-2H3 mast cells sensitized with dinitrophenol (DNP)-specific IgE, the antigen exhibited several mast cell functions, including hexosaminidase release as a marker of degranulation, production of tumor necrosis factor-alpha, and production of immunologically detective leukotrienes.	Dinitrophenols	53-56	tumor necrosis factor	Rattus norvegicus	200-227
15557213-3	2004	To elucidate this question, rat OPN was tagged with dinitrophenol groups and administered to rats either intravenously or by infusion with an osmotic minipump through a "surgical window" in the bone of the hemimandible.	Dinitrophenols	52-65	secreted phosphoprotein 1	Rattus norvegicus	32-35
11978788-6	2002	AMPK activator dinitrophenol had effects on ERK, aPKCs, and 2-DOG uptake similar to those of AICAR.	Dinitrophenols	15-28	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	0-4
12096103-7	2002	H2O2 was formed at the expense of NADH only in the presence of Mn2+ and dinitrophenol by the extract from the micropylar endosperm in which peroxidase activity was present.	Dinitrophenols	72-85	peroxidase	Solanum lycopersicum	140-150
11978788-6	2002	AMPK activator dinitrophenol had effects on ERK, aPKCs, and 2-DOG uptake similar to those of AICAR.	Dinitrophenols	15-28	Eph receptor B1	Rattus norvegicus	44-47
11171597-7	2001	These data suggest that cellular ATP depletion by glucosamine, NaN3, and DNP exerts differential effects on basal and insulin-stimulated glucose transport and that ATP depletion per se does not induce insulin resistance in 3T3-L1 adipocytes.	Dinitrophenols	73-76	insulin	Homo sapiens	118-125
11382920-6	2001	Exposure to rotenone, DNP, and lactate increased the NAD(P)H/NAD(P) ratio, MTT-reduction, and eNOS mRNA also in parallel.	Dinitrophenols	22-25	nitric oxide synthase 3	Homo sapiens	94-98
11959799-4	2002	In the cells sensitized with anti-dinitrophenol (DNP) IgE, DNP-human serum albumin (DNP-HSA) and thapsigargin induced degranulation of beta-hexosaminidase and a sustained increase in [Ca(2+)](i).	Dinitrophenols	34-47	O-GlcNAcase	Rattus norvegicus	135-154
10669514-10	2000	Similarly, pretreatment with agents that cause severe metabolic impairment, such as dinitrophenol (DNP), also rendered the CA3 region vulnerable to subsequent hypoxia.	Dinitrophenols	84-97	carbonic anhydrase 3	Homo sapiens	123-126
11117997-7	2000	AMPK in H-2Kb cells is also activated by hyperosmotic stress and the mitochondrial uncoupling agent, dinitrophenol, both of which lead to increased glucose transport.	Dinitrophenols	101-114	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	0-4
10932079-6	2000	FcgammaRII/FcepsilonRI costimulation was typically accomplished by priming cells with anti-dinitrophenol (DNP) IgE and anti-DNP IgG and stimulating with DNP-BSA.	Dinitrophenols	91-104	Fc epsilon receptor Ia	Homo sapiens	11-22
10669514-10	2000	Similarly, pretreatment with agents that cause severe metabolic impairment, such as dinitrophenol (DNP), also rendered the CA3 region vulnerable to subsequent hypoxia.	Dinitrophenols	99-102	carbonic anhydrase 3	Homo sapiens	123-126
9105692-13	1997	KCN, DNP and FCCP inhibited [Ca2+]i responses to tolbutamide to a much greater extent than those to A-4166.	Dinitrophenols	5-8	carbonic anhydrase 2	Rattus norvegicus	29-32
9602253-3	1998	METHOD OF STUDY: Supernatants of cultures of murine placentae were added to a mouse immunoglobulin (Ig) G1 hybridoma culture which produced anti-dinitrophenol (anti-DNP) antibodies.	Dinitrophenols	145-158	immunoglobulin heavy constant gamma 1 (G1m marker)	Mus musculus	84-106
9862751-5	1999	The dinitrophenol-specific and total IgE in the serum were higher in IL-5 transgenic mice.	Dinitrophenols	4-17	interleukin 5	Mus musculus	69-73
16535314-3	1996	The rate of As(V) reduction in slurries was enhanced by addition of the electron donor lactate, H(inf2), or glucose, whereas the respiratory inhibitor/uncoupler dinitrophenol, rotenone, or 2-heptyl-4-hydroxyquinoline N-oxide blocked As(V) reduction.	Dinitrophenols	161-174	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	12-17
8901527-4	1996	Protein degradation by proteasomes is ATP-dependent, and ATP depletion by dinitrophenol and 2-deoxyglucose also inhibited apoB degradation in these cells.	Dinitrophenols	74-87	apolipoprotein B	Homo sapiens	122-126
8910204-20	1996	This indicates that the action of DNP involves an elevation of intracellular [Ca2+].	Dinitrophenols	34-37	carbonic anhydrase 2	Rattus norvegicus	78-81
2328723-6	1990	Secretion of IL-1 beta is blocked by methylamine, low temperature or serum free medium, and is increased by raising the culture temperature to 42 degrees C or by the presence of calcium ionophores, brefeldin A, monensin, dinitrophenol or carbonyl cyanide chlorophenylhydrazone.	Dinitrophenols	221-234	interleukin 1 beta	Homo sapiens	13-22
8566061-2	1996	BMMC sensitized to hapten-monoclonal IgE directed against dinitrophenol-bovine serum albumin (DNP-BSA) and challenged with 10 ng/ml DNP-BSA generated beta-hexosaminidase and LTC4-like material which was followed by tumor necrosis factor-alpha (TNF-alpha) and granulocyte-macrophage colony-stimulating factor (GM-CSF) mRNA expression and protein release.	Dinitrophenols	58-71	O-GlcNAcase	Mus musculus	150-169
7488196-2	1995	Apolipoprotein AI-dinitrophenol was prepared by incubating the mixture of apolipoprotein AI and 2,4-dinitrobenzene sulfonic acid sodium salt at pH 8.5.	Dinitrophenols	18-31	APOAI	Bos taurus	0-17
7619042-4	1995	We show here that, in serum-depleted myotubes, dinitrophenol induced translocation of GLUT1 and GLUT4, but not GLUT3.	Dinitrophenols	47-60	solute carrier family 2 member 1	Homo sapiens	86-91
7619042-4	1995	We show here that, in serum-depleted myotubes, dinitrophenol induced translocation of GLUT1 and GLUT4, but not GLUT3.	Dinitrophenols	47-60	solute carrier family 2 member 4	Homo sapiens	96-101
7999634-3	1994	Dinitrophenol causes rapid creatine kinase efflux, extensive loss of immunolabelling for desmin and dystrophin, and abnormal myosin immunolabelling.	Dinitrophenols	0-13	desmin	Rattus norvegicus	89-95
7999634-3	1994	Dinitrophenol causes rapid creatine kinase efflux, extensive loss of immunolabelling for desmin and dystrophin, and abnormal myosin immunolabelling.	Dinitrophenols	0-13	dystrophin	Rattus norvegicus	100-110
8206928-7	1994	The release of internalized intact 125I-insulin was 6-fold greater in M than in WT fibroblasts and was almost completely inhibited by dinitrophenol, whereas insulin degradation by M cells was 4-fold decreased as compared with WT.	Dinitrophenols	134-147	insulin	Homo sapiens	40-47
7512056-4	1994	Transport of 125I-LIF was competed by cotreatment with unlabeled LIF and was blocked by cotreatment with dinitrophenol.	Dinitrophenols	105-118	LIF, interleukin 6 family cytokine	Rattus norvegicus	18-21
8095048-13	1993	Recycling of GC/ANF-R was impaired by chloroquine, dinitrophenol, and low temperature (22 degrees C).	Dinitrophenols	51-64	natriuretic peptide type A	Mus musculus	16-19
1280164-2	1992	For example, the inhibitors dinitrophenol-tyrosine and tyrphostins act at the enzyme level to inhibit phosphorylation of all substrates by c-Src and v-Src kinases.	Dinitrophenols	28-41	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus	139-144
1280164-2	1992	For example, the inhibitors dinitrophenol-tyrosine and tyrphostins act at the enzyme level to inhibit phosphorylation of all substrates by c-Src and v-Src kinases.	Dinitrophenols	28-41	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus	141-144
1516140-2	1992	When 0.01 mM of dinitrophenol was used the junctional conductance (gj) remained unchanged for at least 8 min if cell 1 (normal) was pulsed at low rate (0.04 Hz).	Dinitrophenols	16-29	carboxyl ester lipase pseudogene	Homo sapiens	112-118
1516140-5	1992	With 0.05 mM of dinitrophenol cell uncoupling was produced if cell 1 (normal) was stimulated at 4 Hz for 25-30 sec.	Dinitrophenols	16-29	carboxyl ester lipase pseudogene	Homo sapiens	62-68
1786300-4	1991	Perifusion of caput tubules with 0.1 mM dinitrophenol or potassium cyanide or 100 micrograms/ml cyclohexamide significantly reduced proluminal 3H-androgen movement, but tubules perifused with control medium would not support antigrade 3H-androgen movement in the absence of native lumen fluids which contain androgen-binding protein.	Dinitrophenols	40-53	sex hormone binding globulin	Rattus norvegicus	308-332
1826093-4	1991	Addition of dinitrophenol altered the release of Ca2+ to an uptake on the fetal circuit and enhanced Ca2+ uptake on the maternal circuit.	Dinitrophenols	12-25	carbonic anhydrase 2	Homo sapiens	49-52
1826093-4	1991	Addition of dinitrophenol altered the release of Ca2+ to an uptake on the fetal circuit and enhanced Ca2+ uptake on the maternal circuit.	Dinitrophenols	12-25	carbonic anhydrase 2	Homo sapiens	101-104
9244183-8	1996	Conversion of A into B was also prevented in sec7 cells by the presence of dinitrophenol, a poison that depletes ATP levels, indicating that processing is dependent upon intracellular transport which involves ER --> Golgi and/or, at least, one intra-Golgi step(s).	Dinitrophenols	75-88	Arf family guanine nucleotide exchange factor SEC7	Saccharomyces cerevisiae S288C	45-49
7488196-3	1995	Four to six dinitrophenol groups were found to be conjugated with an apolipoprotein AI molecule without any obvious impairment of its binding activity to the binding proteins.	Dinitrophenols	12-25	APOAI	Bos taurus	69-86
7542782-2	1995	Cross-linking the surface IgE receptors with dinitrophenol-conjugated bovine serum albumin initiates secretion in RBL cells with concomitant spreading of the cell body.	Dinitrophenols	45-58	albumin	Rattus norvegicus	77-90
8449947-3	1993	After exposure of mitochondria to the dinitrophenol derivative of etomoxir-CoA (DNP-Et-CoA, a covalent inhibitor of CPT I), followed by detergent solubilization and blue Sepharose chromatography, the DNP-Et-labeled CPT I could be readily visualized on immunoblots using an anti-DNP monoclonal antibody.	Dinitrophenols	38-51	carnitine palmitoyltransferase 1B	Rattus norvegicus	116-121
1287564-8	1992	Investigation of muscle mitochondrial function at 1 y of age revealed a severe mitochondrial ATP-synthase deficiency (oligomycin-sensitive, dinitrophenol-stimulated Mg2+ ATPase activity: 27 nmol x min-1 x (mg protein)-1, control range 223-673 nmol x min-1 x (mg protein)-1.	Dinitrophenols	140-153	mucin 7, secreted	Homo sapiens	165-168
1445281-4	1992	Pretreatment of cells with the lysosomotropic agent chloroquine and the energy depleter dinitrophenol led to an increase in the intracellular 125I-ANF radioactivity.	Dinitrophenols	88-101	natriuretic peptide A	Rattus norvegicus	147-150
1802709-1	1991	Dinitrophenol (DNP)-beta-glucuronidase and mannosylated anti-DNP IgG, which are endocytosed by the mannose receptor and delivered to lysosomes, were previously developed as probes for examination of fusion between early endosomes in a cell-free system.	Dinitrophenols	0-13	glucuronidase beta	Homo sapiens	20-38
1802709-1	1991	Dinitrophenol (DNP)-beta-glucuronidase and mannosylated anti-DNP IgG, which are endocytosed by the mannose receptor and delivered to lysosomes, were previously developed as probes for examination of fusion between early endosomes in a cell-free system.	Dinitrophenols	15-18	glucuronidase beta	Homo sapiens	20-38
1802709-5	1991	Pulse-chase studies using a DNP-derivatized transferrin-alkaline phosphatase conjugate showed that a recycling ligand was always found in light intracellular vesicles that were capable of fusion to early endosomes in vitro.	Dinitrophenols	28-31	transferrin	Homo sapiens	44-55
2161214-3	1990	Dinitrophenol and GDP have the same activating effects on KATP channels as NPPB or intracellular Cl- substitution.	Dinitrophenols	0-13	natriuretic peptide B	Homo sapiens	75-79
2526354-4	1989	ATP, at activating concentrations, competed with dinitrophenol and with the anions SCN-, CN- and HCO3- for the same binding sites of myosin, whereas ADP did not compete with them.	Dinitrophenols	49-62	myosin heavy chain 14	Homo sapiens	133-139
34256102-0	2021	Dinitrophenol-mediated modulation of an anti-PD-L1 VHH for Fc-dependent effector functions and prolonged serum half-life.	Dinitrophenols	0-13	CD274 molecule	Homo sapiens	45-50
35611945-4	2022	The pGr-MoS2/GCE exhibited selectivity towards DHBI, in the presence of other toxic contaminants and metal ions such as phenol, dinitrophenol, trinitrophenol, urea and glucose, Hg(II), Ca(II), Ni(II), Zn(II), Cu(II), Na(I) and K(I).	Dinitrophenols	128-141	progesterone receptor	Homo sapiens	4-7
2555193-3	1989	Addition of 2-deoxyglucose and dinitrophenol (agents that efficiently deplete cellular ATP) to the growth medium of these cells inhibited ODC degradation.	Dinitrophenols	31-44	ornithine decarboxylase 1	Homo sapiens	138-141
2783134-2	1989	Incubation with a medium containing dinitrophenol and 2-deoxy-glucose in place of glucose caused ATP depletion and blocked the turnover of ornithine decarboxylase, even after addition of spermidine.	Dinitrophenols	36-49	ornithine decarboxylase 1	Homo sapiens	139-162
2469744-7	1989	Oligomycin, dinitrophenol, and 1799, a fluorinated uncoupler of oxidative phosphorylation, all produced IFN-suppressive effects in heteroploid human cells.	Dinitrophenols	12-25	interferon alpha 1	Homo sapiens	104-107
3291555-1	1988	Dinitrophenol (DNP), an inhibitor of endocytosis of hormone receptors, Tris, an inhibitor of recycling and chloroquine, an inhibitor of lysosomal degradation, all decreased the binding of insulin and inhibited the development of hormonal imprinting in Tetrahymena.	Dinitrophenols	0-13	insulin	Homo sapiens	188-195
3182843-2	1988	This study shows that plasma membrane-derived vesicles containing receptor-bound ligands (e.g. aggregated anti-dinitrophenol (DNP) IgG bound to Fc receptors) fuse with early endosomes containing DNP-beta-glucuronidase in a cell-free system.	Dinitrophenols	111-124	glucuronidase beta	Homo sapiens	199-217
3360775-3	1988	Dinitrophenol-derivatized beta-glucuronidase (DNP-beta-glucuronidase), a ligand for the mannose receptor, was endocytosed by one population of J774 E clone cells, and mannose-derivatized monoclonal anti-DNP IgG (Man-IgG) was internalized by a second set of cells.	Dinitrophenols	0-13	glucuronidase, beta	Mus musculus	26-44
3360775-3	1988	Dinitrophenol-derivatized beta-glucuronidase (DNP-beta-glucuronidase), a ligand for the mannose receptor, was endocytosed by one population of J774 E clone cells, and mannose-derivatized monoclonal anti-DNP IgG (Man-IgG) was internalized by a second set of cells.	Dinitrophenols	0-13	glucuronidase, beta	Mus musculus	50-68
2459120-15	1988	Finally, exposure of insulin-treated cells (1 nM for 5 min) to dinitrophenol (1 mM for 5 min) reversed insulin action, consistent with reports of reversal of insulin"s activation of the phosphodiesterase.	Dinitrophenols	63-76	insulin	Homo sapiens	21-28
2459120-15	1988	Finally, exposure of insulin-treated cells (1 nM for 5 min) to dinitrophenol (1 mM for 5 min) reversed insulin action, consistent with reports of reversal of insulin"s activation of the phosphodiesterase.	Dinitrophenols	63-76	insulin	Homo sapiens	103-110
2459120-15	1988	Finally, exposure of insulin-treated cells (1 nM for 5 min) to dinitrophenol (1 mM for 5 min) reversed insulin action, consistent with reports of reversal of insulin"s activation of the phosphodiesterase.	Dinitrophenols	63-76	insulin	Homo sapiens	103-110
3291555-1	1988	Dinitrophenol (DNP), an inhibitor of endocytosis of hormone receptors, Tris, an inhibitor of recycling and chloroquine, an inhibitor of lysosomal degradation, all decreased the binding of insulin and inhibited the development of hormonal imprinting in Tetrahymena.	Dinitrophenols	15-18	insulin	Homo sapiens	188-195
3494532-2	1987	C9 cells were established from BALB/c mice primed with syngeneic DNP-SC subcutaneously; they proliferated and produced IL-2 and MIF in a DNP-specific, I-A-restricted manner.	Dinitrophenols	65-68	interleukin 2	Mus musculus	119-123
3334994-4	1988	The increased cytotoxicity was paralleled by similar increases in DNA cross-linking (melphalan: DMF 2.2, HN2: DNF 2.5).	Dinitrophenols	110-113	MT-RNR2 like 2 (pseudogene)	Homo sapiens	105-108
3335000-9	1988	Dinitrophenol, however, in combination with NaF or iodoacetate decreased DDP accumulation.	Dinitrophenols	0-13	translocase of inner mitochondrial membrane 8A	Homo sapiens	73-76
3494532-2	1987	C9 cells were established from BALB/c mice primed with syngeneic DNP-SC subcutaneously; they proliferated and produced IL-2 and MIF in a DNP-specific, I-A-restricted manner.	Dinitrophenols	65-68	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	Mus musculus	128-131
3494532-2	1987	C9 cells were established from BALB/c mice primed with syngeneic DNP-SC subcutaneously; they proliferated and produced IL-2 and MIF in a DNP-specific, I-A-restricted manner.	Dinitrophenols	137-140	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	Mus musculus	128-131
3760196-7	1986	p alpha-ETF was detected when the cells were labeled in the presence of dinitrophenol or rhodamine 6G.	Dinitrophenols	72-85	electron transfer flavoprotein subunit alpha	Homo sapiens	2-11
3024009-5	1986	Another well-characterized B-cell factor is T-cell replacing factor (TRF), which, when secreted by the murine T-cell hybridoma B151K12, is defined by two activities: induction of IgM secretion by BCL1 leukaemic B-cell line; and induction of secondary anti-dinitrophenol (DNP) immunoglobulin G (IgG) synthesis in vitro by DNP-prime B cells.	Dinitrophenols	256-269	interleukin 5	Mus musculus	44-67
3024009-5	1986	Another well-characterized B-cell factor is T-cell replacing factor (TRF), which, when secreted by the murine T-cell hybridoma B151K12, is defined by two activities: induction of IgM secretion by BCL1 leukaemic B-cell line; and induction of secondary anti-dinitrophenol (DNP) immunoglobulin G (IgG) synthesis in vitro by DNP-prime B cells.	Dinitrophenols	256-269	interleukin 5	Mus musculus	69-72
3016176-4	1986	The formation of this complex is inhibited by the addition of unlabeled nerve growth factor, metabolic energy inhibitors (dinitrophenol and NaF), and of sulfhydryl reagents.	Dinitrophenols	122-135	nerve growth factor	Gallus gallus	72-91
3741137-5	1986	Probenecid and sulphinpyrazone, specific competitive inhibitors of the anion transport system, and dinitrophenol, a metabolic inhibitor as well as a competitive inhibitor of anion transport, reduced PCBD-NAC transport.	Dinitrophenols	99-112	pterin-4 alpha-carbinolamine dehydratase 1	Rattus norvegicus	199-203
3020615-1	1986	Rat IgE pleurisy was induced by the injection of di-nitrophenol-conjugated bovine serum albumin (DNP-BSA) 48 hours after the intrapleural injection of rat anti-DNP-IgE serum.	Dinitrophenols	49-63	albumin	Rattus norvegicus	82-95
3697685-10	1986	), cyt c (29 +/- 6%), and cyt b (19 +/- 2%) was induced by addition of 2,4-DNP.	Dinitrophenols	71-78	cytochrome b, mitochondrial	Rattus norvegicus	26-31
2933414-2	1985	We have used dinitrophenol-conjugated bovine serum albumin (DNP-BSA) as well as the fluorescent antigen, DNP-B-phycoerythrin, and the electron-dense antigen, DNP-BSA-gold, to investigate dynamic membrane and cytoskeletal events associated with the release of [3H]serotonin from anti-DNP-IgE-primed RBL-2H3 cells.	Dinitrophenols	13-26	albumin	Rattus norvegicus	45-58
3002843-1	1985	EPR spectroscopy was used to study phenobarbital influence on the kinetics of paramagnetic complexes variability of metal proteins--cytochrome P-450 and iron-sulfur proteins of rat liver in acute oral poisoning with the dinitrophenol pesticides DNOK and dinoseb.	Dinitrophenols	220-233	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	132-148
3002843-2	1985	It was proved experimentally that the barbiturate favoured marked prevention of the decrease of the content of cytochrome P-450 and iron-sulfur proteins, thereby protecting the detoxifying and energy liver system from dinitrophenol-induced injuries.	Dinitrophenols	218-231	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	111-127
2859691-1	1985	In skeletal muscle from a patient with a mitochondrial myopathy and muscular carnitine deficiency, histochemical analysis demonstrated that mitochondrial ATPase showed activation with loss of latency even before addition of the uncoupler dinitrophenol (DNP).	Dinitrophenols	253-256	ATP synthase F1 subunit epsilon	Homo sapiens	140-160
3988798-6	1985	When we incubated transfected HeLa cells with dinitrophenol, a known inhibitor of mitochondrial import, the only form of newly synthesized OTC detected was the precursor.	Dinitrophenols	46-59	ornithine transcarbamylase	Homo sapiens	139-142
3882405-8	1985	Dinitrophenol, which blocks metabolic oxidation, also partially reversed the effect of 50 nM PRL although it was without any significant effect on control levels.	Dinitrophenols	0-13	prolactin	Rattus norvegicus	93-96
2579678-9	1985	Moreover, uptake and degradation of alpha 2-macroglobulin X trypsin was much more sensitive than insulin to the action of metabolic inhibitors such as dinitrophenol and cyanide.	Dinitrophenols	151-164	alpha-2-macroglobulin	Rattus norvegicus	36-57
6600717-6	1983	Preexposure to aerosolized dinitrophenol-OA could not enhance anti-dinitrophenol IgE response.	Dinitrophenols	27-40	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	41-43
6325878-2	1984	In 3T3 cells, dinitrophenol and 2-deoxyglucose, agents which reduce ATP production, inhibited the rapid degradation of p53 and the slower breakdown of total cell protein.	Dinitrophenols	14-27	transformation related protein 53, pseudogene	Mus musculus	119-122
6327744-6	1984	Other agents that lowered ATP levels, including antimycin, dinitrophenol, and 2-deoxyglucose, also raised insulin binding.	Dinitrophenols	59-72	insulin	Homo sapiens	106-113
6133682-4	1983	By contrast, DDT and several p,p"-substituted alpha-trichlomethylbenzylanilines were strong inhibitors of the ATPase activity in the presence of the uncoupler, dinitrophenol.	Dinitrophenols	160-173	dynein axonemal heavy chain 8	Homo sapiens	110-116
6229344-4	1984	Nevertheless, the FcR- gamma B-cell-enriched populations caused intensive plaque-forming cell (PFC) responses to dinitrophenol (DNP), whereas FcR+ gamma B-cell-enriched populations generated weak responses.	Dinitrophenols	113-126	Fc receptor, IgE, high affinity I, gamma polypeptide	Mus musculus	18-28
6229344-4	1984	Nevertheless, the FcR- gamma B-cell-enriched populations caused intensive plaque-forming cell (PFC) responses to dinitrophenol (DNP), whereas FcR+ gamma B-cell-enriched populations generated weak responses.	Dinitrophenols	128-131	Fc receptor, IgE, high affinity I, gamma polypeptide	Mus musculus	18-28
6453612-0	1981	Studies of the kinetics of the isolated mitochondrial ATPase using dinitrophenol as a probe.	Dinitrophenols	67-80	ATP synthase F1 subunit epsilon	Homo sapiens	40-60
6754726-10	1982	The Arrhenius plot of the basal glucose transport activity determined in the presence of dinitrophenol was apparently linear from 10 to 37 degrees C and parallel to that of the plus insulin activity measured either in the presence or absence of dinitrophenyl.	Dinitrophenols	89-102	insulin	Homo sapiens	182-189
6288084-1	1982	The uncoupler-stimulated mitochondrial ATPase of four human tumors, mouse kidney, brain and fetal liver exhibited a characteristic behavior when preincubated with the H+-conducting uncouplers, dinitrophenol, CCCP, S-13 and gramicidin.	Dinitrophenols	193-206	dynein axonemal heavy chain 8	Homo sapiens	39-45
6288084-5	1982	The effect of preincubation with dinitrophenol on the tumor mitochondria could not be accounted for by dinitrophenol-induced Mg2+ efflux, since the differential effects of dinitrophenol and valinomycin (+ K+) remained even when ATPase activity was determined in presence of Mg2+.	Dinitrophenols	33-46	dynein axonemal heavy chain 8	Homo sapiens	228-234
6288084-6	1982	Small amounts of ATP and ADP in the preincubation mixture containing dinitrophenol protected against the decay of the ATPase activity, implicating the exchangeable adenine nucleotides in the tumor mitochondria.	Dinitrophenols	69-82	dynein axonemal heavy chain 8	Homo sapiens	118-124
7065204-8	1982	Addition of an inhibitor or an uncoupler of mitochondrial respiration [sodium cyanide (5 X 10(-3) M) or dinitrophenol (5 X 10(-4) M), respectively] in the perfusate caused significant decreases in reoxygenation-induced tissue Ca2+ gain.	Dinitrophenols	104-117	carbonic anhydrase 2	Oryctolagus cuniculus	226-229
6453612-2	1981	Dinitrophenol and maleate anions increase VATP on the "washed", isolated, mitochondrial ATPase.	Dinitrophenols	0-13	ATP synthase F1 subunit epsilon	Homo sapiens	74-94
7008850-1	1981	The hexose transport of insulin-pretreated (80 pM) adipocytes remained elevated for at least 45 min when the cells were depleted of ATP by treatment with dinitrophenol.	Dinitrophenols	154-167	insulin	Homo sapiens	24-31
6454449-1	1981	Tissue specificity of mitochondrial respiration stimulation under the effect of a soluble phase of liver cells (SPC) is preserved by addition to dinitrophenol but is reserved in the presence of oligomycin.	Dinitrophenols	145-158	surfactant protein C	Rattus norvegicus	112-115
7000584-4	1980	Agents believed to inhibit intralysosomal degradation of various proteins also inhibited the degradation of 125I-insulin by H4 cells (chloroquine, ammonium chloride, procaine, and lidocaine); inhibitors of energy production (dinitrophenol, sodium cyanide) inhibited degradation; an agent which inhibits microtubule function (vinblastine) blocked insulin degradation; and methylamine, reported to prevent receptor aggregation,2 also interfered with insulin processing.	Dinitrophenols	225-238	insulin	Homo sapiens	113-120
7288188-1	1981	Intraperitoneal injection into mice of dinitrophenol-conjugated ovalbumin entrapped in autologous erythrocyte ghosts gave rise to an increase of anti-dinitrophenol antibody production without use of artificial adjuvants.	Dinitrophenols	39-52	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	64-73
7288188-1	1981	Intraperitoneal injection into mice of dinitrophenol-conjugated ovalbumin entrapped in autologous erythrocyte ghosts gave rise to an increase of anti-dinitrophenol antibody production without use of artificial adjuvants.	Dinitrophenols	150-163	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	64-73
14725-0	1976	[Influence of dinitrophenol, octanol and toluene upon pH-dependence of ca-ATPase activity of heavy meromyosin].	Dinitrophenols	14-27	dynein axonemal heavy chain 8	Homo sapiens	74-80
115198-4	1979	Comparative studies using human serum indicated that T4 binding by serum T4-binding prealbumin (TBPA) was inhibited with DNP and salicylate, and that binding of T4 and T3 by serum T4-binding globulin (TBG) was decreased only with DPH.	Dinitrophenols	121-124	transthyretin	Homo sapiens	73-94
115198-4	1979	Comparative studies using human serum indicated that T4 binding by serum T4-binding prealbumin (TBPA) was inhibited with DNP and salicylate, and that binding of T4 and T3 by serum T4-binding globulin (TBG) was decreased only with DPH.	Dinitrophenols	121-124	transthyretin	Homo sapiens	96-100
40224-7	1979	Dinitrophenol, a H+ carrier, prevented synthesis at delta muH of 310 mV.	Dinitrophenols	0-13	familial progressive hyperpigmentation 1	Homo sapiens	58-61
698046-4	1978	The antimetabolites sodium azide and dinitrophenol partially protected L cells from TNF, suggesting that actively metabolizing cells are the most sensitive.	Dinitrophenols	37-50	tumor necrosis factor	Oryctolagus cuniculus	84-87
222966-3	1979	In the present study, we have shown that inhibitors of oxidative metabolism (rotenone, dinitrophenol, and methylene blue) selectively inhibit either vasopressin-stimulated water flow or vasopressin-stimulated urea transport.	Dinitrophenols	87-100	arginine vasopressin	Homo sapiens	149-160
222966-3	1979	In the present study, we have shown that inhibitors of oxidative metabolism (rotenone, dinitrophenol, and methylene blue) selectively inhibit either vasopressin-stimulated water flow or vasopressin-stimulated urea transport.	Dinitrophenols	87-100	arginine vasopressin	Homo sapiens	186-197
588575-0	1977	Effects of adenine nucleotide translocase inhibitors on dinitrophenol-induced Ca2+ efflux from pig heart mitochondria.	Dinitrophenols	56-69	carbonic anhydrase 2	Sus scrofa	78-81
588575-2	1977	However, bongkrekic acid, but not atractyloside, inhibits dinitrophenol-induced Ca2+ efflux and H+ uptake.	Dinitrophenols	58-71	carbonic anhydrase 2	Sus scrofa	80-83
140852-8	1977	From studies with dinitrophenol it can be concluded that this substance activates the myosin ATPase present in type I fibres especially.	Dinitrophenols	18-31	myosin heavy chain 14	Homo sapiens	86-92
140852-8	1977	From studies with dinitrophenol it can be concluded that this substance activates the myosin ATPase present in type I fibres especially.	Dinitrophenols	18-31	dynein axonemal heavy chain 8	Homo sapiens	93-99
14725-1	1976	It is found that dinitrophenol, octanol and toluene produce similar effects on pH-dependence of ATPase of myosin and heavy meromyosin (HMM), i.e. they decrease or remove the neutral suppression of ATPase activity.	Dinitrophenols	17-30	dynein axonemal heavy chain 8	Homo sapiens	96-102
14725-1	1976	It is found that dinitrophenol, octanol and toluene produce similar effects on pH-dependence of ATPase of myosin and heavy meromyosin (HMM), i.e. they decrease or remove the neutral suppression of ATPase activity.	Dinitrophenols	17-30	myosin heavy chain 14	Homo sapiens	106-133
14725-1	1976	It is found that dinitrophenol, octanol and toluene produce similar effects on pH-dependence of ATPase of myosin and heavy meromyosin (HMM), i.e. they decrease or remove the neutral suppression of ATPase activity.	Dinitrophenols	17-30	dynein axonemal heavy chain 8	Homo sapiens	197-203
128977-1	1975	The hydrolysis of adenosine triphosphate in the mandibular enamel organ demonstrated that the Mg++-activated ATPase was destroyed by pre-treatment with either heat or alcohol, substrate specific for ATP, stimulated by the addition of glutathione or dinitrophenol, and inhibited by oligomycin.	Dinitrophenols	249-262	dynein, axonemal, heavy chain 8	Mus musculus	109-115
4273188-0	1973	Affinities of ATP for the dinitrophenol-induced ATPase.	Dinitrophenols	26-39	dynein axonemal heavy chain 8	Homo sapiens	48-54
4853028-1	1974	The purification of coliphage MS2 dinitrophenol (DNP) conjugates provided a system for localization of the single molecule of A-protein in the capsid of the MS2 phage particle.	Dinitrophenols	49-52	MS2	Homo sapiens	30-33
4853028-1	1974	The purification of coliphage MS2 dinitrophenol (DNP) conjugates provided a system for localization of the single molecule of A-protein in the capsid of the MS2 phage particle.	Dinitrophenols	49-52	MS2	Homo sapiens	157-160
4229072-0	1967	A "latent" dinitrophenol-stimulated ATPase in red-cell ghosts.	Dinitrophenols	11-24	dynein axonemal heavy chain 8	Homo sapiens	36-42
5507401-0	1970	[Influence of dinitrophenol on the catalytic process of methemoglobin transformation in erythrocytes, induced by methylene blue].	Dinitrophenols	14-27	hemoglobin subunit gamma 2	Homo sapiens	56-69
4234234-0	1968	[The nature of the stimulus action of dinitrophenol on the ATPase activity of myosin].	Dinitrophenols	38-51	myosin heavy chain 14	Homo sapiens	78-84
4684678-0	1973	[Effect of dinitrophenol and sodium azide on the electrophysiological properties of snail giant neurons].	Dinitrophenols	11-24	snail family transcriptional repressor 1	Homo sapiens	84-89
14020472-0	1963	On the nature of the lipid substances inhibiting the dinitrophenol-induced ATPase activity during mitochondrial aging.	Dinitrophenols	53-66	dynein axonemal heavy chain 8	Homo sapiens	75-81
13651228-0	1959	A mechanism for the effects of dinitrophenol and temperature on the hydrolytic activity of myosin.	Dinitrophenols	31-44	myosin heavy chain 14	Homo sapiens	91-97
13637990-0	1959	Effect of dinitrophenol on the interaction between myosin and nucleotides.	Dinitrophenols	10-23	myosin heavy chain 14	Homo sapiens	51-57
14391292-2	1955	The relationship between the control of structure and the dinitrophenol stimulation of adenosinetriphosphatase in liver mitochondria.	Dinitrophenols	58-71	ATPase Na+/K+ transporting subunit beta 1	Homo sapiens	87-110
33578051-5	2021	We found that rapamycin and spermidine were able to decrease the spontaneous mutation rate at the CAN1 locus, whereas dinitrophenol, metformin, and resveratrol were able to protect yeast against CAN1 mutations induced by ethyl methanesulfonate (EMS).	Dinitrophenols	118-131	arginine permease CAN1	Saccharomyces cerevisiae S288C	195-199
32302339-8	2020	Stimulation of the RBL-2H3 cells with anti-dinitrophenol (DNP) IgE and DNP-conjugated human serum albumin triggers degranulation with the release of beta-hexosaminidase.	Dinitrophenols	43-56	O-GlcNAcase	Homo sapiens	149-168
31923239-8	2020	CONCLUSIONS: The present results raise the possibility of non-invasively evaluating the mouse rod mitochondrial energy ecosystem using new DNP-assisted OCT and MRI in vivo assays.	Dinitrophenols	139-142	plexin A2	Mus musculus	152-155
31494149-4	2019	We assessed whether pre-exposure of bone marrow-derived mast cells (BMMCs) to 20 nm AgNPs enhanced degranulation and activation to an allergen (dinitrophenol-conjugated human serum albumin) by measuring beta-hexosaminidase release, LTB4 and IL-6 production.	Dinitrophenols	144-157	albumin	Homo sapiens	175-188
30135425-3	2018	Vaccination of mice against dinitrophenol (DNP) followed by systemic administration of DNP targeted to tumors by conjugation to a VEGF or osteopontin aptamer elicits potent FcR dependent, T cell mediated, antitumor immunity.	Dinitrophenols	28-41	vascular endothelial growth factor A	Mus musculus	130-134
30804812-5	2018	We proposed that net slow influx/efflux of Ca2+ after adding DNP and CaCl2 is dependent on whether the DeltapHm gradient is/is not maintained by reciprocal outward H+ pumping by complex V. We found that adding CaCl2 enhanced DNP-induced increases in respiration and decreases in DeltaPsim while [ATP]m decreased, DeltapHm gradient was maintained, and [Ca2+]m continued to increase slowly, indicating net mCa2+ influx via MCU.	Dinitrophenols	61-64	carbonic anhydrase 2	Mus musculus	43-46
30804812-5	2018	We proposed that net slow influx/efflux of Ca2+ after adding DNP and CaCl2 is dependent on whether the DeltapHm gradient is/is not maintained by reciprocal outward H+ pumping by complex V. We found that adding CaCl2 enhanced DNP-induced increases in respiration and decreases in DeltaPsim while [ATP]m decreased, DeltapHm gradient was maintained, and [Ca2+]m continued to increase slowly, indicating net mCa2+ influx via MCU.	Dinitrophenols	61-64	carbonic anhydrase 2	Mus musculus	352-355
30804812-5	2018	We proposed that net slow influx/efflux of Ca2+ after adding DNP and CaCl2 is dependent on whether the DeltapHm gradient is/is not maintained by reciprocal outward H+ pumping by complex V. We found that adding CaCl2 enhanced DNP-induced increases in respiration and decreases in DeltaPsim while [ATP]m decreased, DeltapHm gradient was maintained, and [Ca2+]m continued to increase slowly, indicating net mCa2+ influx via MCU.	Dinitrophenols	61-64	carbonic anhydrase 2	Mus musculus	404-408
30804812-5	2018	We proposed that net slow influx/efflux of Ca2+ after adding DNP and CaCl2 is dependent on whether the DeltapHm gradient is/is not maintained by reciprocal outward H+ pumping by complex V. We found that adding CaCl2 enhanced DNP-induced increases in respiration and decreases in DeltaPsim while [ATP]m decreased, DeltapHm gradient was maintained, and [Ca2+]m continued to increase slowly, indicating net mCa2+ influx via MCU.	Dinitrophenols	61-64	calcium uniporter protein, mitochondrial	Cavia porcellus	421-424
30804812-5	2018	We proposed that net slow influx/efflux of Ca2+ after adding DNP and CaCl2 is dependent on whether the DeltapHm gradient is/is not maintained by reciprocal outward H+ pumping by complex V. We found that adding CaCl2 enhanced DNP-induced increases in respiration and decreases in DeltaPsim while [ATP]m decreased, DeltapHm gradient was maintained, and [Ca2+]m continued to increase slowly, indicating net mCa2+ influx via MCU.	Dinitrophenols	225-228	carbonic anhydrase 2	Mus musculus	43-46
30804812-6	2018	In contrast, with complex V blocked by OMN, adding DNP and CaCl2 caused larger declines in DeltaPsim as well as a slow fall in pHm to near pHe while [Ca2+]m continued to decrease slowly, indicating net mCa2+ efflux in exchange for H+ influx (CHEm) until the DeltapHm gradient was abolished.	Dinitrophenols	51-54	carbonic anhydrase 2	Mus musculus	150-153
30804812-6	2018	In contrast, with complex V blocked by OMN, adding DNP and CaCl2 caused larger declines in DeltaPsim as well as a slow fall in pHm to near pHe while [Ca2+]m continued to decrease slowly, indicating net mCa2+ efflux in exchange for H+ influx (CHEm) until the DeltapHm gradient was abolished.	Dinitrophenols	51-54	carbonic anhydrase 2	Mus musculus	202-206
30135425-3	2018	Vaccination of mice against dinitrophenol (DNP) followed by systemic administration of DNP targeted to tumors by conjugation to a VEGF or osteopontin aptamer elicits potent FcR dependent, T cell mediated, antitumor immunity.	Dinitrophenols	28-41	secreted phosphoprotein 1	Mus musculus	138-149
30135425-3	2018	Vaccination of mice against dinitrophenol (DNP) followed by systemic administration of DNP targeted to tumors by conjugation to a VEGF or osteopontin aptamer elicits potent FcR dependent, T cell mediated, antitumor immunity.	Dinitrophenols	28-41	Fc receptor	Mus musculus	173-176
30135425-3	2018	Vaccination of mice against dinitrophenol (DNP) followed by systemic administration of DNP targeted to tumors by conjugation to a VEGF or osteopontin aptamer elicits potent FcR dependent, T cell mediated, antitumor immunity.	Dinitrophenols	43-46	secreted phosphoprotein 1	Mus musculus	138-149
30135425-3	2018	Vaccination of mice against dinitrophenol (DNP) followed by systemic administration of DNP targeted to tumors by conjugation to a VEGF or osteopontin aptamer elicits potent FcR dependent, T cell mediated, antitumor immunity.	Dinitrophenols	43-46	Fc receptor	Mus musculus	173-176
30135425-3	2018	Vaccination of mice against dinitrophenol (DNP) followed by systemic administration of DNP targeted to tumors by conjugation to a VEGF or osteopontin aptamer elicits potent FcR dependent, T cell mediated, antitumor immunity.	Dinitrophenols	87-90	vascular endothelial growth factor A	Mus musculus	130-134
30135425-3	2018	Vaccination of mice against dinitrophenol (DNP) followed by systemic administration of DNP targeted to tumors by conjugation to a VEGF or osteopontin aptamer elicits potent FcR dependent, T cell mediated, antitumor immunity.	Dinitrophenols	87-90	secreted phosphoprotein 1	Mus musculus	138-149
30135425-3	2018	Vaccination of mice against dinitrophenol (DNP) followed by systemic administration of DNP targeted to tumors by conjugation to a VEGF or osteopontin aptamer elicits potent FcR dependent, T cell mediated, antitumor immunity.	Dinitrophenols	87-90	Fc receptor	Mus musculus	173-176
28450277-6	2017	Despite increased E. coli in DNP-treated NOD2 KD compared with WT cells, there were no differences in the internalization of fluorescent inert beads or dead E. coli particles.	Dinitrophenols	29-32	nucleotide binding oligomerization domain containing 2	Homo sapiens	41-45
29317503-9	2018	Systemic delivery of the DAPK1 inhibitor DAPK6 increased bacterial translocation in DSS- or DNP-treated mice.	Dinitrophenols	92-95	death associated protein kinase 1	Mus musculus	25-30
28821452-7	2017	In vitro studies validated the predicted interaction and showed that Pinocembrin inhibits HDC activity and histamine in IgE-sensitized RBL-2H3 in response to dinitrophenol (DNP)-bovine serum albumin (BSA) stimulation.	Dinitrophenols	158-171	histidine decarboxylase	Homo sapiens	90-93
28821452-7	2017	In vitro studies validated the predicted interaction and showed that Pinocembrin inhibits HDC activity and histamine in IgE-sensitized RBL-2H3 in response to dinitrophenol (DNP)-bovine serum albumin (BSA) stimulation.	Dinitrophenols	173-176	histidine decarboxylase	Homo sapiens	90-93
28131916-4	2017	DNP and C12TPP prevented the body temperature drop and lethality in mice injected with high doses of a SIRS inducer, tumor necrosis factor (TNF).	Dinitrophenols	0-3	tumor necrosis factor	Mus musculus	117-138
28131916-4	2017	DNP and C12TPP prevented the body temperature drop and lethality in mice injected with high doses of a SIRS inducer, tumor necrosis factor (TNF).	Dinitrophenols	0-3	tumor necrosis factor	Mus musculus	140-143
27679575-5	2016	METHODS: RBL-2H3 cells, a basophilic leukemia cell line, were pretreated with 2.5 or 5 microM Vam3 and then stimulated with dinitrophenol-conjugated bovine serum albumin (DNP-BSA) plus lipopolysaccharide (LPS).	Dinitrophenols	124-137	albumin	Rattus norvegicus	156-169
24304834-7	2014	DNP- and NaN3-induced decrease of cellular ATP was significantly augmented by JAK2 inhibitor AG490 and blunted by Na(+)/K(+)-ATPase inhibitor ouabain.	Dinitrophenols	0-3	ATPase Na+/K+ transporting subunit alpha 1 L homeolog	Xenopus laevis	114-131
25445267-6	2015	Of the 13 genes analyzed, ankyrin repeat domain 1 (Ankrd1) and GATA6 were downregulated after DNP treatment and subsequent re-oxygenations.	Dinitrophenols	94-97	ankyrin repeat domain 1	Homo sapiens	26-49
25445267-6	2015	Of the 13 genes analyzed, ankyrin repeat domain 1 (Ankrd1) and GATA6 were downregulated after DNP treatment and subsequent re-oxygenations.	Dinitrophenols	94-97	ankyrin repeat domain 1	Homo sapiens	51-57
25445267-6	2015	Of the 13 genes analyzed, ankyrin repeat domain 1 (Ankrd1) and GATA6 were downregulated after DNP treatment and subsequent re-oxygenations.	Dinitrophenols	94-97	GATA binding protein 6	Homo sapiens	63-68
24304834-6	2014	As a result, in Jurkat T cells, JAK2 activity significantly increased following energy depletion by sodium azide (NaN3) or 2,4- dinitro phenol (DNP).	Dinitrophenols	144-147	Janus kinase 2	Homo sapiens	32-36
24304834-7	2014	DNP- and NaN3-induced decrease of cellular ATP was significantly augmented by JAK2 inhibitor AG490 and blunted by Na(+)/K(+)-ATPase inhibitor ouabain.	Dinitrophenols	0-3	Janus kinase 2 (a protein tyrosine kinase) L homeolog	Xenopus laevis	78-82
24019401-8	2013	Furthermore, dinitrophenol treatment increased urinary protein excretion, kidney vimentin expression, and infiltration of inflammatory cells.	Dinitrophenols	13-26	vimentin	Rattus norvegicus	81-89
22330806-3	2012	MCP-1 release was significantly decreased by 26% (p<0.01) in 24h DNP (30 mumol/L)-treated adipocytes compared to control cells.	Dinitrophenols	68-71	C-C motif chemokine ligand 2	Homo sapiens	0-5
22330806-9	2012	JNK phosphorylation in mature adipocytes was decreased by treatment with either DNP or AICAR (p<0.01).	Dinitrophenols	80-83	mitogen-activated protein kinase 8	Homo sapiens	0-3
22330806-10	2012	Enhanced VEGF(120) secretion with either DNP or AICAR was markedly suppressed by PI3K inhibitor LY294002 (p<0.01).	Dinitrophenols	41-44	vascular endothelial growth factor A	Homo sapiens	9-13
22155143-7	2012	Dinitrophenol and four 4"-hydroxychalconoids also suppressed hepatocyte G6Pase as well as, or more effectively than metformin, whereas the unsubstituted parent compound chalcone, devoid of uncoupling activity, had no effect.	Dinitrophenols	0-13	glucose-6-phosphatase catalytic subunit 1	Rattus norvegicus	72-78
22820943-3	2012	For activation, both NK1R knockdown and control RBL-2H3 cells were sensitized by dinitrophenol (DNP)-specific IgE and stimulated with the antigen DNP-bovine serum albumin (BSA).	Dinitrophenols	81-94	tachykinin receptor 1	Rattus norvegicus	21-25
22820943-3	2012	For activation, both NK1R knockdown and control RBL-2H3 cells were sensitized by dinitrophenol (DNP)-specific IgE and stimulated with the antigen DNP-bovine serum albumin (BSA).	Dinitrophenols	96-99	tachykinin receptor 1	Rattus norvegicus	21-25
22820943-3	2012	For activation, both NK1R knockdown and control RBL-2H3 cells were sensitized by dinitrophenol (DNP)-specific IgE and stimulated with the antigen DNP-bovine serum albumin (BSA).	Dinitrophenols	146-149	tachykinin receptor 1	Rattus norvegicus	21-25
22820943-8	2012	In addition, both calcium mobilization and phosphorylation levels of MAPKs (Erk1/2, JNK, and p38) after DNP-BSA stimulation (via FcepsilonRIota) were decreased due to the inhibition of NK1R expression.	Dinitrophenols	104-107	mitogen activated protein kinase 3	Rattus norvegicus	76-82
22820943-8	2012	In addition, both calcium mobilization and phosphorylation levels of MAPKs (Erk1/2, JNK, and p38) after DNP-BSA stimulation (via FcepsilonRIota) were decreased due to the inhibition of NK1R expression.	Dinitrophenols	104-107	mitogen-activated protein kinase 8	Rattus norvegicus	84-87
22820943-8	2012	In addition, both calcium mobilization and phosphorylation levels of MAPKs (Erk1/2, JNK, and p38) after DNP-BSA stimulation (via FcepsilonRIota) were decreased due to the inhibition of NK1R expression.	Dinitrophenols	104-107	mitogen activated protein kinase 14	Rattus norvegicus	93-96
22820943-8	2012	In addition, both calcium mobilization and phosphorylation levels of MAPKs (Erk1/2, JNK, and p38) after DNP-BSA stimulation (via FcepsilonRIota) were decreased due to the inhibition of NK1R expression.	Dinitrophenols	104-107	tachykinin receptor 1	Rattus norvegicus	185-189
21483800-3	2011	We found that DNP and CR increase citrate synthase activity, PGC-1alpha, cytochrome c oxidase and mitofusin-2 expression, as well as fasting plasma levels of NO  products.	Dinitrophenols	14-17	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	Mus musculus	61-71
21483800-3	2011	We found that DNP and CR increase citrate synthase activity, PGC-1alpha, cytochrome c oxidase and mitofusin-2 expression, as well as fasting plasma levels of NO  products.	Dinitrophenols	14-17	mitofusin 2	Mus musculus	98-109
21483800-4	2011	In addition, eNOS and Akt phosphorylation in skeletal muscle and visceral adipose tissue was activated in fasting CR and DNP animals.	Dinitrophenols	121-124	nitric oxide synthase 3, endothelial cell	Mus musculus	13-17
21483800-4	2011	In addition, eNOS and Akt phosphorylation in skeletal muscle and visceral adipose tissue was activated in fasting CR and DNP animals.	Dinitrophenols	121-124	thymoma viral proto-oncogene 1	Mus musculus	22-25