PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 24464048-9 2014 Both OSU-CG5 (5, 10, and 20 mumol/L) and resveratrol (50, 100, and 200 mumol/L) dose-dependently increased caspase-3/7 activity and PARP level in the cells. OSU-CG5 5-12 caspase 3 Homo sapiens 107-116 24464048-10 2014 Furthermore, both OSU-CG5 and resveratrol induced dose-dependent energy restriction in the cells: they suppressed glucose uptake and Akt phosphorylation, decreased the levels of p-mTOR and p-p70S6K, increased the levels of ER stress response proteins GRP78 and GADD153, and increased the level of beta-TrCP, which led to the downregulation of cyclin D1 and Sp1. OSU-CG5 18-25 heat shock protein family A (Hsp70) member 5 Homo sapiens 251-256 24464048-9 2014 Both OSU-CG5 (5, 10, and 20 mumol/L) and resveratrol (50, 100, and 200 mumol/L) dose-dependently increased caspase-3/7 activity and PARP level in the cells. OSU-CG5 5-12 poly(ADP-ribose) polymerase 1 Homo sapiens 132-136 24464048-10 2014 Furthermore, both OSU-CG5 and resveratrol induced dose-dependent energy restriction in the cells: they suppressed glucose uptake and Akt phosphorylation, decreased the levels of p-mTOR and p-p70S6K, increased the levels of ER stress response proteins GRP78 and GADD153, and increased the level of beta-TrCP, which led to the downregulation of cyclin D1 and Sp1. OSU-CG5 18-25 DNA damage inducible transcript 3 Homo sapiens 261-268 24464048-10 2014 Furthermore, both OSU-CG5 and resveratrol induced dose-dependent energy restriction in the cells: they suppressed glucose uptake and Akt phosphorylation, decreased the levels of p-mTOR and p-p70S6K, increased the levels of ER stress response proteins GRP78 and GADD153, and increased the level of beta-TrCP, which led to the downregulation of cyclin D1 and Sp1. OSU-CG5 18-25 cyclin D1 Homo sapiens 343-352 24464048-10 2014 Furthermore, both OSU-CG5 and resveratrol induced dose-dependent energy restriction in the cells: they suppressed glucose uptake and Akt phosphorylation, decreased the levels of p-mTOR and p-p70S6K, increased the levels of ER stress response proteins GRP78 and GADD153, and increased the level of beta-TrCP, which led to the downregulation of cyclin D1 and Sp1. OSU-CG5 18-25 mechanistic target of rapamycin kinase Homo sapiens 180-184 24464048-10 2014 Furthermore, both OSU-CG5 and resveratrol induced dose-dependent energy restriction in the cells: they suppressed glucose uptake and Akt phosphorylation, decreased the levels of p-mTOR and p-p70S6K, increased the levels of ER stress response proteins GRP78 and GADD153, and increased the level of beta-TrCP, which led to the downregulation of cyclin D1 and Sp1. OSU-CG5 18-25 ribosomal protein S6 kinase B1 Homo sapiens 191-197 23275006-7 2013 The suppressive effect of OSU-CG5 was evidenced by marked decreases in Ki67 immunostaining and proliferating cell nuclear antigen (PCNA) expression in the prostate. OSU-CG5 26-33 antigen identified by monoclonal antibody Ki 67 Mus musculus 71-75 23275006-7 2013 The suppressive effect of OSU-CG5 was evidenced by marked decreases in Ki67 immunostaining and proliferating cell nuclear antigen (PCNA) expression in the prostate. OSU-CG5 26-33 proliferating cell nuclear antigen Mus musculus 95-129 23275006-7 2013 The suppressive effect of OSU-CG5 was evidenced by marked decreases in Ki67 immunostaining and proliferating cell nuclear antigen (PCNA) expression in the prostate. OSU-CG5 26-33 proliferating cell nuclear antigen Mus musculus 131-135