PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
8466925-8	1993	From the change in the thermogram profile with fenvalerate it has been interpreted that it localizes in the acyl chain region of the lipid, possibly between C10 and C16 region and weakens the acyl chain packing.	fenvalerate	47-58	homeobox C10	Homo sapiens	157-160
9461846-4	1997	Moreover, immunoblotting responses of microsomal protein encoded by Cyp6A2 showed that the levels of expression were quantitatively correlated with toxicological tolerance to almost the same group of insecticides (deltamethrin, fipronil, chlorpyriphos ethyl, DDT, fenvalerate, and fenthion).	fenvalerate	264-275	Cytochrome P450-6a2	Drosophila melanogaster	68-74
9183056-3	1997	However, it could ameliorate the toxicity as indicated by decreased hepatic lipid peroxidation (LPO) with a marginal but significant increase in superoxide dismutase and catalase activities following fenvalerate treatment.	fenvalerate	200-211	catalase	Mus musculus	170-178
7821986-5	1994	Fenvalerate significantly increased the cholesterol level in brain, GPT activity in liver and heart, GOT activity in heart, and alkaline phosphatase activity in heart and brain tissue.	fenvalerate	0-11	glutamic--pyruvic transaminase	Homo sapiens	68-71
35343441-4	2022	Both pyrethroids inhibited PG secretion and decreased the amount of diacylglycerol (DAG), which is the second messenger involved in oxytocin signal transmission, and fenvalerate decreased the myosin light-chain kinase (MLCK) level.	fenvalerate	166-177	myosin light chain kinase, smooth muscle	Bos taurus	192-217
8385837-4	1993	These pups also showed a significant decrease in the activity of brain monoamine oxidase and Na+, K(+)-ATPase and a significant increase in acetylcholinesterase from gestational exposure to fenvalerate.	fenvalerate	190-201	acetylcholinesterase	Rattus norvegicus	140-160
8385837-5	1993	Significant decreases were observed during lactation in monoamine oxidase and acetylcholinesterase in fenvalerate-exposed pups and in acetylcholinesterase and Na+, K(+)-ATPase in cypermethrin-exposed pups.	fenvalerate	102-113	acetylcholinesterase	Rattus norvegicus	78-98
35343441-4	2022	Both pyrethroids inhibited PG secretion and decreased the amount of diacylglycerol (DAG), which is the second messenger involved in oxytocin signal transmission, and fenvalerate decreased the myosin light-chain kinase (MLCK) level.	fenvalerate	166-177	myosin light chain kinase, smooth muscle	Bos taurus	219-223
35355317-4	2022	The results showed that BmGAPDH and Bmalpha-tubulin were relatively stable in the midgut after feeding with fenvalerate, BmGAPDH and Bmactin3 were relatively stable in the fat body, and Bmalpha-tubulin and Bmactin3 were relatively stable in the hemolymph, indicating that Bmactin3 was the most suitable RG when evaluating fenvalerate, followed by BmGAPDH and Bmalpha-tubulin.	fenvalerate	108-119	glyceraldehyde-3-phosphate dehydrogenase	Bombyx mori	24-31
35355317-4	2022	The results showed that BmGAPDH and Bmalpha-tubulin were relatively stable in the midgut after feeding with fenvalerate, BmGAPDH and Bmactin3 were relatively stable in the fat body, and Bmalpha-tubulin and Bmactin3 were relatively stable in the hemolymph, indicating that Bmactin3 was the most suitable RG when evaluating fenvalerate, followed by BmGAPDH and Bmalpha-tubulin.	fenvalerate	108-119	glyceraldehyde-3-phosphate dehydrogenase	Bombyx mori	347-354
35355317-4	2022	The results showed that BmGAPDH and Bmalpha-tubulin were relatively stable in the midgut after feeding with fenvalerate, BmGAPDH and Bmactin3 were relatively stable in the fat body, and Bmalpha-tubulin and Bmactin3 were relatively stable in the hemolymph, indicating that Bmactin3 was the most suitable RG when evaluating fenvalerate, followed by BmGAPDH and Bmalpha-tubulin.	fenvalerate	322-333	glyceraldehyde-3-phosphate dehydrogenase	Bombyx mori	24-31
32672501-0	2020	Metabolism of bifenthrin, beta-cyfluthrin, lambda-cyhalothrin, cyphenothrin and esfenvalerate by rat and human cytochrome P450 and carboxylesterase enzymes.	fenvalerate	80-93	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	111-147
33656234-0	2021	Key proteins of proteome underlying sperm malformation of rats exposed to low fenvalerate doses are highly related to P53.	fenvalerate	78-89	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	118-121
33656234-11	2021	Results indicate that key DE proteins of proteome underlying sperm malformations of rats exposed to low Fen doses are highly related to P53.	fenvalerate	104-107	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	136-139
3597919-0	1987	Effect on milk production of controlling muscid flies, and reducing fly-avoidance behaviour, by the use of Fenvalerate ear tags during the dry period.	fenvalerate	107-118	Weaning weight-maternal milk	Bos taurus	10-14
7175102-2	1982	Given orally, either in a single dose of 60 mg/kg or in a six daily doses of 20 mg/kg, fenvalerate reduced the activity of the B6-dependent kynurenine hydrolase (KH), but increased that of kynurenine aminotransferase (KATE) and beta-glucuronidase (beta-Glase).	fenvalerate	87-98	glucuronidase, beta	Mus musculus	228-246
7175102-2	1982	Given orally, either in a single dose of 60 mg/kg or in a six daily doses of 20 mg/kg, fenvalerate reduced the activity of the B6-dependent kynurenine hydrolase (KH), but increased that of kynurenine aminotransferase (KATE) and beta-glucuronidase (beta-Glase).	fenvalerate	87-98	glucuronidase, beta	Mus musculus	248-258
30307764-0	2019	Fenvalerate induces oxidative hepatic lesions through an overload of intracellular calcium triggered by the ERK/IKK/NF-kappaB pathway.	fenvalerate	0-11	Eph receptor B1	Rattus norvegicus	108-111
31734597-0	2020	Fenvalerate triggers Parkinson-like symptom during zebrafish development through initiation of autophagy and p38 MAPK/mTOR signaling pathway.	fenvalerate	0-11	mitogen-activated protein kinase 14a	Danio rerio	109-112
31734597-0	2020	Fenvalerate triggers Parkinson-like symptom during zebrafish development through initiation of autophagy and p38 MAPK/mTOR signaling pathway.	fenvalerate	0-11	mechanistic target of rapamycin kinase	Danio rerio	118-122
31734597-7	2020	Besides, FEN activated autophagy by the enhanced expressions of p-mTOR, and LC3-II but the reduction of p62.	fenvalerate	9-12	mechanistic target of rapamycin kinase	Danio rerio	66-70
31734597-7	2020	Besides, FEN activated autophagy by the enhanced expressions of p-mTOR, and LC3-II but the reduction of p62.	fenvalerate	9-12	general transcription factor IIH, polypeptide 1	Danio rerio	104-107
31734597-8	2020	Further, FEN initially activated p-p38 MAPK followed by p-mTOR, which triggered the transcription of genes responsible for autophagy process and prompted the Lewy bodies neuron generation leading to the PD-like symptoms.	fenvalerate	9-12	mitogen-activated protein kinase 14a	Danio rerio	35-38
31734597-8	2020	Further, FEN initially activated p-p38 MAPK followed by p-mTOR, which triggered the transcription of genes responsible for autophagy process and prompted the Lewy bodies neuron generation leading to the PD-like symptoms.	fenvalerate	9-12	mechanistic target of rapamycin kinase	Danio rerio	58-62
31734597-10	2020	These results suggest that FEN might cause parkinson-like symptom during zebrafish development through induction of autophagy and activation of p38 MAPK/mTOR signaling pathway.	fenvalerate	27-30	mitogen-activated protein kinase 14a	Danio rerio	144-147
31734597-10	2020	These results suggest that FEN might cause parkinson-like symptom during zebrafish development through induction of autophagy and activation of p38 MAPK/mTOR signaling pathway.	fenvalerate	27-30	mechanistic target of rapamycin kinase	Danio rerio	153-157
31889868-7	2020	In liver, catalase activity was found to be less in fenvalerate exposed fish than control fish.	fenvalerate	52-63	catalase	Danio rerio	10-18
32693020-12	2020	In addition, TRalpha1 was declined only in females exposed to 5.0 mg/kg fenvalerate.	fenvalerate	72-83	detected by T cells 1	Mus musculus	13-21
32666189-7	2020	The scFv also showed 23.91%, 13.41%, 1.15%, 1.00%, and 0.56% cross-reactivity with phenothrin, deltamethrin, fenvalerate, beta-cypermethrin, and fenpropathrin.	fenvalerate	109-120	immunglobulin heavy chain variable region	Homo sapiens	4-8
31538121-5	2019	However, fenvalerate showed dose-dependent inverse agonistic activity toward rat CAR, and this activity was reduced after metabolism.	fenvalerate	9-20	nuclear receptor subfamily 1, group I, member 3	Rattus norvegicus	81-84
29968265-6	2018	Meanwhile, TUNEL-positive germ cells significantly increased in 1 and 50 mg kg-1  day-1 fenvalerate exposure groups, and the expression of caspase-8 and caspase-3 in rat testes were also significantly up-regulated.	fenvalerate	88-99	caspase 3	Rattus norvegicus	153-162
31524104-0	2019	Role of the gene Phlda1 in fenvalerate-induced apoptosis and testicular damage in Sprague-Dawley rats.	fenvalerate	27-38	pleckstrin homology-like domain, family A, member 1	Rattus norvegicus	17-23
28949029-9	2018	Decreased expression of pro-apoptotic Bcl-2 family proteins (Noxa and Bid) and increased expression of anti-apoptotic proteins (Bcl-xL, Mcl-1 and XIAP) were observed after combined treatment with Fen and CdCl2 .	fenvalerate	196-199	BCL2 apoptosis regulator	Homo sapiens	38-43
28949029-9	2018	Decreased expression of pro-apoptotic Bcl-2 family proteins (Noxa and Bid) and increased expression of anti-apoptotic proteins (Bcl-xL, Mcl-1 and XIAP) were observed after combined treatment with Fen and CdCl2 .	fenvalerate	196-199	BCL2 like 1	Homo sapiens	128-134
22311421-12	2012	We assert that this increase in the abundance of competing species, as well as sub-lethal effects of esfenvalerate, caused the unexpectedly prolonged effects of esfenvalerate on populations of Daphnia spp.	fenvalerate	161-174	histocompatibility minor 13	Homo sapiens	201-204
28949029-9	2018	Decreased expression of pro-apoptotic Bcl-2 family proteins (Noxa and Bid) and increased expression of anti-apoptotic proteins (Bcl-xL, Mcl-1 and XIAP) were observed after combined treatment with Fen and CdCl2 .	fenvalerate	196-199	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	136-141
28369636-9	2017	Interestingly, placental TRalpha1 and TRbeta1 mRNAs were reduced in mice exposed to fenvalerate.	fenvalerate	84-95	thyroid hormone receptor alpha	Mus musculus	25-33
28369636-11	2017	Further analysis showed that placental Vegfalpha and Igf2, several target genes of TR signaling, were down-regulated in fenvalerate-exposed mice.	fenvalerate	120-131	vascular endothelial growth factor A	Mus musculus	39-48
28369636-11	2017	Further analysis showed that placental Vegfalpha and Igf2, several target genes of TR signaling, were down-regulated in fenvalerate-exposed mice.	fenvalerate	120-131	insulin-like growth factor 2	Mus musculus	53-57
29040059-6	2017	Thus, data suggested that Fen inhibits testosterone synthesis via pathways involving intracellular Ca2+ and clock genes (Bmal1, Rev-Erbalpha, Roralpha) as well as StAR mRNA expression in TM3 cells.	fenvalerate	26-29	aryl hydrocarbon receptor nuclear translocator-like	Mus musculus	121-126
29040059-6	2017	Thus, data suggested that Fen inhibits testosterone synthesis via pathways involving intracellular Ca2+ and clock genes (Bmal1, Rev-Erbalpha, Roralpha) as well as StAR mRNA expression in TM3 cells.	fenvalerate	26-29	nuclear receptor subfamily 1, group D, member 1	Mus musculus	128-140
29040059-6	2017	Thus, data suggested that Fen inhibits testosterone synthesis via pathways involving intracellular Ca2+ and clock genes (Bmal1, Rev-Erbalpha, Roralpha) as well as StAR mRNA expression in TM3 cells.	fenvalerate	26-29	RAR-related orphan receptor alpha	Mus musculus	142-150
26961610-0	2016	Methoxychlor and fenvalerate induce neuronal death by reducing GluR2 expression.	fenvalerate	17-28	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	63-68
26961610-5	2016	Treatment of cultured rat cortical neurons with 1 or 10 microM methoxychlor and fenvalerate for 9 days selectively decreased GluR2 protein expression; the expression of other AMPA receptor subunits GluR1, GluR3, and GluR4 did not change under the same conditions.	fenvalerate	80-91	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	125-130
26961610-5	2016	Treatment of cultured rat cortical neurons with 1 or 10 microM methoxychlor and fenvalerate for 9 days selectively decreased GluR2 protein expression; the expression of other AMPA receptor subunits GluR1, GluR3, and GluR4 did not change under the same conditions.	fenvalerate	80-91	glutamate ionotropic receptor AMPA type subunit 1	Rattus norvegicus	198-203
26961610-5	2016	Treatment of cultured rat cortical neurons with 1 or 10 microM methoxychlor and fenvalerate for 9 days selectively decreased GluR2 protein expression; the expression of other AMPA receptor subunits GluR1, GluR3, and GluR4 did not change under the same conditions.	fenvalerate	80-91	glutamate ionotropic receptor AMPA type subunit 4	Rattus norvegicus	216-221
26961610-8	2016	These results suggest that long-term exposure to methoxychlor and fenvalerate decreases GluR2 protein expression, leading to neuronal death via overactivation of GluR2-lacking AMPA and NMDA receptors.	fenvalerate	66-77	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	88-93
26961610-8	2016	These results suggest that long-term exposure to methoxychlor and fenvalerate decreases GluR2 protein expression, leading to neuronal death via overactivation of GluR2-lacking AMPA and NMDA receptors.	fenvalerate	66-77	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	162-167
24875908-3	2014	The binding abilities of pesticides to CAT followed the order: fenvalerate>deltamethrin>disulfoton>isofenphos-methyl>carbaryl>malathion>isocarbophos>dimethoate>dipterex>acephate>methomyl>methamidophos, which was generally similar to the order of determination sensitivity of pesticides.	fenvalerate	63-74	catalase	Homo sapiens	39-42
24722372-0	2014	An enantioselective amidase from Burkholderia multivorans for the stereoselective synthesis of esfenvalerate.	fenvalerate	95-108	DM80_RS17440	Burkholderia multivorans	20-27
25182815-9	2014	Compared with the sham operation group (CA3 (11.00 +- 1.12), DG (10.67 +- 1.15)), the sham operation with fenvalerate group (CA3 (18.67 +- 2.07), DG (16.33 +- 1.53)) showed significant increase in number of astrocytes (GFAP-positive) cells (P < 0.05).	fenvalerate	106-117	carbonic anhydrase 3	Mus musculus	125-128
22634058-6	2013	Pyrethroids, e.g. deltamethrin, fenvalerate and lambda-cyhalothrin, potently inhibited CYP2D6.	fenvalerate	32-43	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	87-93
22634058-7	2013	CYP3A4 activity was moderately inhibited by fenvalerate and potently by alpha-cypermethrin.	fenvalerate	44-55	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	0-6
23504978-10	2013	In contrast, long-term effects of esfenvalerate on Daphnia spp., a taxon that did not benefit from elevated temperatures, were observed twice as long under warming than under ambient conditions.	fenvalerate	34-47	histocompatibility minor 13	Homo sapiens	59-62
22850687-0	2012	An essential role of p27 downregulation in fenvalerate-induced cell growth in human uterine leiomyoma and smooth muscle cells.	fenvalerate	43-54	interferon alpha inducible protein 27	Homo sapiens	21-24
22437841-0	2012	Expression of calmodulin in germ cells is associated with fenvalerate-induced male reproductive toxicity.	fenvalerate	58-69	calmodulin 2	Mus musculus	14-24
22437841-3	2012	The present study explored the effects of fenvalerate on the expression of calmodulin in mouse testis and GC-2spd(ts) cells, and its association with fenvalerate-induced male reproductive toxicity.	fenvalerate	42-53	calmodulin 2	Mus musculus	75-85
22437841-10	2012	Meanwhile, both mRNA and protein expression of calmodulin were significantly increased in the testes of mice exposed to fenvalerate compared to control mice.	fenvalerate	120-131	calmodulin 2	Mus musculus	47-57
22437841-11	2012	Moreover, in the in vitro study, 5 muM fenvalerate significantly increased the expression of calmodulin at the mRNA and protein levels in GC-2spd(ts) cells after 8 h of incubation and sustained these levels for at least 24 h. Collectively, these data suggested that enhanced expression of calmodulin correlates with male reproductive damage induced by fenvalerate.	fenvalerate	39-50	calmodulin 2	Mus musculus	93-103
22437841-11	2012	Moreover, in the in vitro study, 5 muM fenvalerate significantly increased the expression of calmodulin at the mRNA and protein levels in GC-2spd(ts) cells after 8 h of incubation and sustained these levels for at least 24 h. Collectively, these data suggested that enhanced expression of calmodulin correlates with male reproductive damage induced by fenvalerate.	fenvalerate	39-50	calmodulin 2	Mus musculus	289-299
22437841-11	2012	Moreover, in the in vitro study, 5 muM fenvalerate significantly increased the expression of calmodulin at the mRNA and protein levels in GC-2spd(ts) cells after 8 h of incubation and sustained these levels for at least 24 h. Collectively, these data suggested that enhanced expression of calmodulin correlates with male reproductive damage induced by fenvalerate.	fenvalerate	352-363	calmodulin 2	Mus musculus	93-103
29576712-7	2018	SUMMARY: Fenvalerate showed apex glide score toward CD8 immune receptor, while fluvalinate confirmed top-ranked binding with CD4 and CD45 immune proteinsIn addition, cypermethrin outcame in top glide score against CD28 immune receptorTop dock hits (Type 2) pyrethroids have shown probable toxicity targets toward AOFA: Amine oxidase (flavin-containing) A and PGH1: Prostaglandin G/H synthase 1, respectively.	fenvalerate	9-20	CD8a molecule	Homo sapiens	52-55
26267048-3	2015	Fenvalerate exposure produced significant elevation in lipid peroxidation (LPO), glutathione peroxidase (GPx), while it produced significant decline in blood glutathione (GSH) levels, superoxide dismutase (SOD) and catalase (CAT).	fenvalerate	0-11	catalase	Bubalus bubalis	215-223
26267048-3	2015	Fenvalerate exposure produced significant elevation in lipid peroxidation (LPO), glutathione peroxidase (GPx), while it produced significant decline in blood glutathione (GSH) levels, superoxide dismutase (SOD) and catalase (CAT).	fenvalerate	0-11	catalase	Bubalus bubalis	225-228
25182815-10	2014	Compared with the sham operation with fenvalerate group, the ovariectomized with fenvalerate group (CA3 (12.00 +- 1.00), DG (11.68 +- 1.16)) showed significant decrease in GFAP-positive cells (P < 0.05).	fenvalerate	81-92	carbonic anhydrase 3	Mus musculus	100-103
23548413-4	2013	Fenvalerate significantly changed the methylation status of angiotensin I-converting enzyme (Ace), forkhead box O3 (Foxo3a), huntingtin-associated protein 1 (Hap1), nuclear receptor subfamily 3 (Nr3c2), promyelocytic leukemia (Pml), and Prostaglandin F2 receptor negative regulator (Ptgfrn) genes in paternal mice sperm genomic DNA.	fenvalerate	0-11	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	60-91
23548413-4	2013	Fenvalerate significantly changed the methylation status of angiotensin I-converting enzyme (Ace), forkhead box O3 (Foxo3a), huntingtin-associated protein 1 (Hap1), nuclear receptor subfamily 3 (Nr3c2), promyelocytic leukemia (Pml), and Prostaglandin F2 receptor negative regulator (Ptgfrn) genes in paternal mice sperm genomic DNA.	fenvalerate	0-11	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	93-96
23548413-4	2013	Fenvalerate significantly changed the methylation status of angiotensin I-converting enzyme (Ace), forkhead box O3 (Foxo3a), huntingtin-associated protein 1 (Hap1), nuclear receptor subfamily 3 (Nr3c2), promyelocytic leukemia (Pml), and Prostaglandin F2 receptor negative regulator (Ptgfrn) genes in paternal mice sperm genomic DNA.	fenvalerate	0-11	forkhead box O3	Mus musculus	116-122
23548413-4	2013	Fenvalerate significantly changed the methylation status of angiotensin I-converting enzyme (Ace), forkhead box O3 (Foxo3a), huntingtin-associated protein 1 (Hap1), nuclear receptor subfamily 3 (Nr3c2), promyelocytic leukemia (Pml), and Prostaglandin F2 receptor negative regulator (Ptgfrn) genes in paternal mice sperm genomic DNA.	fenvalerate	0-11	huntingtin-associated protein 1	Mus musculus	125-156
23548413-4	2013	Fenvalerate significantly changed the methylation status of angiotensin I-converting enzyme (Ace), forkhead box O3 (Foxo3a), huntingtin-associated protein 1 (Hap1), nuclear receptor subfamily 3 (Nr3c2), promyelocytic leukemia (Pml), and Prostaglandin F2 receptor negative regulator (Ptgfrn) genes in paternal mice sperm genomic DNA.	fenvalerate	0-11	huntingtin-associated protein 1	Mus musculus	158-162
23548413-4	2013	Fenvalerate significantly changed the methylation status of angiotensin I-converting enzyme (Ace), forkhead box O3 (Foxo3a), huntingtin-associated protein 1 (Hap1), nuclear receptor subfamily 3 (Nr3c2), promyelocytic leukemia (Pml), and Prostaglandin F2 receptor negative regulator (Ptgfrn) genes in paternal mice sperm genomic DNA.	fenvalerate	0-11	nuclear receptor subfamily 3, group C, member 2	Mus musculus	195-200
23548413-4	2013	Fenvalerate significantly changed the methylation status of angiotensin I-converting enzyme (Ace), forkhead box O3 (Foxo3a), huntingtin-associated protein 1 (Hap1), nuclear receptor subfamily 3 (Nr3c2), promyelocytic leukemia (Pml), and Prostaglandin F2 receptor negative regulator (Ptgfrn) genes in paternal mice sperm genomic DNA.	fenvalerate	0-11	promyelocytic leukemia	Mus musculus	227-230
23548413-4	2013	Fenvalerate significantly changed the methylation status of angiotensin I-converting enzyme (Ace), forkhead box O3 (Foxo3a), huntingtin-associated protein 1 (Hap1), nuclear receptor subfamily 3 (Nr3c2), promyelocytic leukemia (Pml), and Prostaglandin F2 receptor negative regulator (Ptgfrn) genes in paternal mice sperm genomic DNA.	fenvalerate	0-11	prostaglandin F2 receptor negative regulator	Mus musculus	237-281
23548413-4	2013	Fenvalerate significantly changed the methylation status of angiotensin I-converting enzyme (Ace), forkhead box O3 (Foxo3a), huntingtin-associated protein 1 (Hap1), nuclear receptor subfamily 3 (Nr3c2), promyelocytic leukemia (Pml), and Prostaglandin F2 receptor negative regulator (Ptgfrn) genes in paternal mice sperm genomic DNA.	fenvalerate	0-11	prostaglandin F2 receptor negative regulator	Mus musculus	283-289
23102722-0	2013	Kinetic and product study of the heterogeneous reactions of NO3 radicals with suspended resmethrin, phenothrin, and fenvalerate particles.	fenvalerate	116-127	NBL1, DAN family BMP antagonist	Homo sapiens	60-63
21279716-0	2011	Fenvalerate induces germ cell apoptosis in mouse testes through the Fas/FasL signaling pathway.	fenvalerate	0-11	Fas ligand (TNF superfamily, member 6)	Mus musculus	72-76
22210404-0	2012	Involvement of IGF-I signaling pathway in the regulation of steroidogenesis in mouse Leydig cells treated with fenvalerate.	fenvalerate	111-122	insulin-like growth factor 1	Mus musculus	15-20
22210404-2	2012	In this study, the same cell line was used to investigate the potential involvement of insulin-like growth factor I (IGF-I) signaling pathway in the downregulation of steroidogenesis by fenvalerate.	fenvalerate	186-197	insulin-like growth factor 1	Mus musculus	87-115
22210404-2	2012	In this study, the same cell line was used to investigate the potential involvement of insulin-like growth factor I (IGF-I) signaling pathway in the downregulation of steroidogenesis by fenvalerate.	fenvalerate	186-197	insulin-like growth factor 1	Mus musculus	117-122
22210404-3	2012	Results showed that fenvalerate treatment decreased IGF-I secretion significantly which was consistent with the reduced expression of IGF-I mRNA.	fenvalerate	20-31	insulin-like growth factor 1	Mus musculus	52-57
22210404-3	2012	Results showed that fenvalerate treatment decreased IGF-I secretion significantly which was consistent with the reduced expression of IGF-I mRNA.	fenvalerate	20-31	insulin-like growth factor 1	Mus musculus	134-139
22210404-6	2012	In addition, phosphorylation of ERK1/2 was also suppressed by fenvalerate.	fenvalerate	62-73	mitogen-activated protein kinase 3	Mus musculus	32-38
22210404-7	2012	The results suggest that the mechanism by which fenvalerate decreased steroid hormone production might involve the impairment of IGF-I signal pathway by attenuating the IGF-I production and ERK1/2 phosphorylation.	fenvalerate	48-59	insulin-like growth factor 1	Mus musculus	129-134
22210404-7	2012	The results suggest that the mechanism by which fenvalerate decreased steroid hormone production might involve the impairment of IGF-I signal pathway by attenuating the IGF-I production and ERK1/2 phosphorylation.	fenvalerate	48-59	insulin-like growth factor 1	Mus musculus	169-174
22210404-7	2012	The results suggest that the mechanism by which fenvalerate decreased steroid hormone production might involve the impairment of IGF-I signal pathway by attenuating the IGF-I production and ERK1/2 phosphorylation.	fenvalerate	48-59	mitogen-activated protein kinase 3	Mus musculus	190-196
21769927-4	2011	Correlation of ALP activity and mRNA levels at different developmental stages, or following application of 20-hydroxyecdysone (20E) and insecticide fenvalerate, suggests that Nl-ALP1 and Nl-ALP2 might encode a soluble (sALP) and a membrane-bound ALP (mALP), respectively.	fenvalerate	148-159	alopecia, recessive	Mus musculus	15-18
21769927-4	2011	Correlation of ALP activity and mRNA levels at different developmental stages, or following application of 20-hydroxyecdysone (20E) and insecticide fenvalerate, suggests that Nl-ALP1 and Nl-ALP2 might encode a soluble (sALP) and a membrane-bound ALP (mALP), respectively.	fenvalerate	148-159	alopecia, recessive	Mus musculus	178-181
21279716-7	2011	Additional experiments showed that fenvalerate increased the level of active caspase-8 and caspase-3 in testes.	fenvalerate	35-46	caspase 8	Mus musculus	77-86
21279716-7	2011	Additional experiments showed that fenvalerate increased the level of active caspase-8 and caspase-3 in testes.	fenvalerate	35-46	caspase 3	Mus musculus	91-100
21279716-8	2011	In addition, fenvalerate upregulated the expression of Fas and FasL in testes.	fenvalerate	13-24	Fas ligand (TNF superfamily, member 6)	Mus musculus	63-67
21279716-12	2011	Taken together, these results suggest that fenvalerate induces germ cell apoptosis in testes through the Fas/FasL signaling pathway.	fenvalerate	43-54	Fas ligand (TNF superfamily, member 6)	Mus musculus	109-113
20599767-7	2010	In addition, dexamethasone synergized esfenvalerate (an insecticide and a PXR activator) in inducing CYP3A23 and stimulating the CYP3A23 promoter.	fenvalerate	38-51	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	101-108
21557984-4	2011	Fenvalerate treated human sera showed serum complement activation as evident by significant (p<0.05) increase in C3b, C3d and C3a levels and a significant (p<0.05) decline in CH50 levels.	fenvalerate	0-11	complement C3	Homo sapiens	116-119
21557984-4	2011	Fenvalerate treated human sera showed serum complement activation as evident by significant (p<0.05) increase in C3b, C3d and C3a levels and a significant (p<0.05) decline in CH50 levels.	fenvalerate	0-11	endogenous retrovirus group K member 13	Homo sapiens	121-124
21232584-4	2011	Thus, the aim of the present study was to investigate the effects of pubertal fenvalerate exposure on the synthesis of T and E(2) and the expression of androgen receptor (AR) and estrogen receptors (ERs) in cerebral cortex.	fenvalerate	78-89	androgen receptor	Mus musculus	152-169
21232584-4	2011	Thus, the aim of the present study was to investigate the effects of pubertal fenvalerate exposure on the synthesis of T and E(2) and the expression of androgen receptor (AR) and estrogen receptors (ERs) in cerebral cortex.	fenvalerate	78-89	androgen receptor	Mus musculus	171-173
21232584-7	2011	In agreement with the decrease in T and E(2) syntheses, the expression of 17beta-HSD, a key enzyme for T synthesis, was significantly reduced in cerebral cortex of fenvalerate-exposed males.	fenvalerate	164-175	hydroxysteroid (17-beta) dehydrogenase 1	Mus musculus	74-84
21232584-8	2011	Conversely, in females, the expression of 17beta-HSD in cerebral cortex was mildly up-regulated by fenvalerate and the level of T and E(2) was mildly increased.	fenvalerate	99-110	hydroxysteroid (17-beta) dehydrogenase 1	Mus musculus	42-52
21232584-10	2011	Interestingly, the expression of AR in cerebral cortex was up-regulated in male and female mice exposed to fenvalerate, whereas pubertal fenvalerate exposure did not affect the level of ERalpha and ERbeta in cerebral cortex.	fenvalerate	107-118	androgen receptor	Mus musculus	33-35
21232584-11	2011	Taken together, these results suggest that pubertal fenvalerate exposure disrupts T and E(2) synthesis and the expression of AR in cerebral cortex.	fenvalerate	52-63	androgen receptor	Mus musculus	125-127
22125391-3	2011	The crystallographic coordinates of the compound was extrapolated to docking studies to elucidate the action of fenvalarate against neural cytoskeletal protein of insect and mammalian beta-actin.	fenvalerate	112-123	POTE ankyrin domain family member F	Homo sapiens	184-194
22125391-4	2011	A strong affinity was observed in binding of fenvalarate with insect beta-actin (-7.71kcal/mol, Ki = 2.23microM) indicating it as a potent insecticide and moderate toxicity towards mammalian beta-actin (-7.07kcal/mol, Ki=6.54microM).	fenvalerate	45-56	POTE ankyrin domain family member F	Homo sapiens	69-79
22125391-4	2011	A strong affinity was observed in binding of fenvalarate with insect beta-actin (-7.71kcal/mol, Ki = 2.23microM) indicating it as a potent insecticide and moderate toxicity towards mammalian beta-actin (-7.07kcal/mol, Ki=6.54microM).	fenvalerate	45-56	POTE ankyrin domain family member F	Homo sapiens	191-201
20599767-7	2010	In addition, dexamethasone synergized esfenvalerate (an insecticide and a PXR activator) in inducing CYP3A23 and stimulating the CYP3A23 promoter.	fenvalerate	38-51	nuclear receptor subfamily 1, group I, member 2	Rattus norvegicus	74-77
20599767-7	2010	In addition, dexamethasone synergized esfenvalerate (an insecticide and a PXR activator) in inducing CYP3A23 and stimulating the CYP3A23 promoter.	fenvalerate	38-51	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	129-136
20599767-8	2010	The full promoter of CYP3A23 (-1445/+74) was activated in a similar pattern as the changes in PXR mRNA in response to dexamethasone, esfenvalerate and co-treatment.	fenvalerate	133-146	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	21-28
20599767-8	2010	The full promoter of CYP3A23 (-1445/+74) was activated in a similar pattern as the changes in PXR mRNA in response to dexamethasone, esfenvalerate and co-treatment.	fenvalerate	133-146	nuclear receptor subfamily 1, group I, member 2	Rattus norvegicus	94-97
20599767-12	2010	The different responding patterns among CYP3A23 reporters point to an involvement of multiple transcriptional events in the regulation of CYP3A23 expression by dexamethasone, esfenvalerate and both.	fenvalerate	175-188	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	40-47
20599767-12	2010	The different responding patterns among CYP3A23 reporters point to an involvement of multiple transcriptional events in the regulation of CYP3A23 expression by dexamethasone, esfenvalerate and both.	fenvalerate	175-188	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	138-145
17576809-0	2007	Identification of rat and human cytochrome p450 isoforms and a rat serum esterase that metabolize the pyrethroid insecticides deltamethrin and esfenvalerate.	fenvalerate	143-156	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	43-47
20570613-7	2010	Fenvalerate also down-regulated the expression of ogg1 and dlx2 genes in a concentration dependent manner, which indicated that the oxidative-DNA repair system as well as neurogenesis were impaired.	fenvalerate	0-11	8-oxoguanine DNA glycosylase	Danio rerio	50-54
20570613-7	2010	Fenvalerate also down-regulated the expression of ogg1 and dlx2 genes in a concentration dependent manner, which indicated that the oxidative-DNA repair system as well as neurogenesis were impaired.	fenvalerate	0-11	distal-less homeobox 2a	Danio rerio	59-63
19892000-8	2010	These results suggested that fenvalerate restrained the follicular growth, and inhibited steroidogenesis by reducing StAR and P450scc gene expression, which might further contribute to the fenvalerate-induced reproductive dysfunction.	fenvalerate	29-40	steroidogenic acute regulatory protein	Rattus norvegicus	117-121
19892000-8	2010	These results suggested that fenvalerate restrained the follicular growth, and inhibited steroidogenesis by reducing StAR and P450scc gene expression, which might further contribute to the fenvalerate-induced reproductive dysfunction.	fenvalerate	29-40	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	126-133
19683566-7	2009	Additional experiment showed that lactational fenvalerate exposure markedly reduced mRNA and protein levels of testicular P450scc, a testosterone (T) synthesis enzyme.	fenvalerate	46-57	cytochrome P450, family 11, subfamily a, polypeptide 1	Mus musculus	122-129
19683566-8	2009	Consistent with down-regulation of testicular P450scc, the level of serum and testicular T at weaning was significantly decreased in pups whose mothers were exposed to fenvalerate during lactation.	fenvalerate	168-179	cytochrome P450, family 11, subfamily a, polypeptide 1	Mus musculus	46-53
20183062-5	2009	Deltamethrin and fenvalerate were potent inhibitors of CYP2D6 (IC(50) values of approximately 3 micro M) while lambda-cyhalothrin potently inhibited both CYP2D6 and CYP3A4-mediated activities (IC(50)"s about 3-4 micro M).	fenvalerate	17-28	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	55-61
18053657-4	2008	Fenvalerate treatment inhibited progesterone secretion induced by human chorionic gonadotropin (hCG), cholera toxin (CT) or forskolin and decreased cAMP levels induced by hCG, but not by CT or forskolin, which suggested a repaired site on the upstream components of G protein or G protein per se by fenvalerate in the cAMP-mediated signal pathway.	fenvalerate	0-11	hypertrichosis 2 (generalised, congenital)	Homo sapiens	96-99
18053657-4	2008	Fenvalerate treatment inhibited progesterone secretion induced by human chorionic gonadotropin (hCG), cholera toxin (CT) or forskolin and decreased cAMP levels induced by hCG, but not by CT or forskolin, which suggested a repaired site on the upstream components of G protein or G protein per se by fenvalerate in the cAMP-mediated signal pathway.	fenvalerate	0-11	hypertrichosis 2 (generalised, congenital)	Homo sapiens	171-174
18053657-6	2008	In addition, fenvalerate decreased steroidogenic acute regulatory protein (StAR) mRNA and protein levels, and also profoundly inhibited the activity of P450 side chain cleavage enzyme (P450scc) which was consistent with the decreased expression of P450scc mRNA and protein in MLTC-1 cells.	fenvalerate	13-24	steroidogenic acute regulatory protein	Mus musculus	35-73
18053657-6	2008	In addition, fenvalerate decreased steroidogenic acute regulatory protein (StAR) mRNA and protein levels, and also profoundly inhibited the activity of P450 side chain cleavage enzyme (P450scc) which was consistent with the decreased expression of P450scc mRNA and protein in MLTC-1 cells.	fenvalerate	13-24	steroidogenic acute regulatory protein	Mus musculus	75-79
18053657-6	2008	In addition, fenvalerate decreased steroidogenic acute regulatory protein (StAR) mRNA and protein levels, and also profoundly inhibited the activity of P450 side chain cleavage enzyme (P450scc) which was consistent with the decreased expression of P450scc mRNA and protein in MLTC-1 cells.	fenvalerate	13-24	cytochrome P450, family 11, subfamily a, polypeptide 1	Mus musculus	152-183
18053657-6	2008	In addition, fenvalerate decreased steroidogenic acute regulatory protein (StAR) mRNA and protein levels, and also profoundly inhibited the activity of P450 side chain cleavage enzyme (P450scc) which was consistent with the decreased expression of P450scc mRNA and protein in MLTC-1 cells.	fenvalerate	13-24	cytochrome P450, family 11, subfamily a, polypeptide 1	Mus musculus	185-192
18053657-6	2008	In addition, fenvalerate decreased steroidogenic acute regulatory protein (StAR) mRNA and protein levels, and also profoundly inhibited the activity of P450 side chain cleavage enzyme (P450scc) which was consistent with the decreased expression of P450scc mRNA and protein in MLTC-1 cells.	fenvalerate	13-24	cytochrome P450, family 11, subfamily a, polypeptide 1	Mus musculus	248-255
18053657-7	2008	These results suggested that fenvalerate might inhibit progesterone production by attenuating cAMP generation and inhibiting StAR expression and P450scc activity.	fenvalerate	29-40	steroidogenic acute regulatory protein	Mus musculus	125-129
18053657-7	2008	These results suggested that fenvalerate might inhibit progesterone production by attenuating cAMP generation and inhibiting StAR expression and P450scc activity.	fenvalerate	29-40	cytochrome P450, family 11, subfamily a, polypeptide 1	Mus musculus	145-152
18538810-11	2008	Cypermethrin, beta-cyfluthrin, esfenvalerate and fenpropathrin all modified sodium channel function; effects were significantly greater on Na(v)1.3/beta(3) than on Na(v)1.2/beta(1) channels.	fenvalerate	31-44	sodium voltage-gated channel alpha subunit 3	Rattus norvegicus	139-147
17576809-3	2007	Using a parent depletion approach, rat and human cytochromes P450 (P450s) were screened for their ability to eliminate deltamethrin or esfenvalerate during in vitro incubations.	fenvalerate	135-148	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	61-65
17576809-3	2007	Using a parent depletion approach, rat and human cytochromes P450 (P450s) were screened for their ability to eliminate deltamethrin or esfenvalerate during in vitro incubations.	fenvalerate	135-148	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	67-72
17576809-5	2007	Human CYP2C9 metabolized esfenvalerate but not deltamethrin.	fenvalerate	25-38	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	6-12
17576809-6	2007	Rat and human P450s that metabolize esfenvalerate and deltamethrin do so with similar kinetics.	fenvalerate	36-49	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	14-19
17490606-1	2007	We studied the effects of four commonly used insecticides (methylparathion, endosulfan, cypermethrin and fenvalerate) on P-glycoprotein isolated from multidrug-resistant cells.	fenvalerate	105-116	ATP binding cassette subfamily B member 1	Homo sapiens	121-135
16626760-5	2006	In our model, fifteen of the tested pesticides were found to agonize the ERalpha-mediated transcription in a dose-dependent manner and DDT, trans-nonachlor, chlordane, fenvalerate and toxaphene were also capable to activate ERbeta.	fenvalerate	168-179	Era like 12S mitochondrial rRNA chaperone 1	Homo sapiens	73-80
16855054-9	2006	Results of CE metabolism revealed that human carboxylesterase 1 (hCE-1) was markedly more active toward deltamethrin than the class 1 rat CEs hydrolase A and B and the class 2 human CE (hCE-2); however, hydrolase A metabolized esfenvalerate 2-fold faster than hCE-1, whereas hydrolase B and hCE-1 hydrolyzed esfenvalerate at equal rates.	fenvalerate	227-240	carboxylesterase 1	Homo sapiens	45-63
16855054-9	2006	Results of CE metabolism revealed that human carboxylesterase 1 (hCE-1) was markedly more active toward deltamethrin than the class 1 rat CEs hydrolase A and B and the class 2 human CE (hCE-2); however, hydrolase A metabolized esfenvalerate 2-fold faster than hCE-1, whereas hydrolase B and hCE-1 hydrolyzed esfenvalerate at equal rates.	fenvalerate	227-240	carboxylesterase 1	Homo sapiens	65-70
16855054-9	2006	Results of CE metabolism revealed that human carboxylesterase 1 (hCE-1) was markedly more active toward deltamethrin than the class 1 rat CEs hydrolase A and B and the class 2 human CE (hCE-2); however, hydrolase A metabolized esfenvalerate 2-fold faster than hCE-1, whereas hydrolase B and hCE-1 hydrolyzed esfenvalerate at equal rates.	fenvalerate	308-321	carboxylesterase 1	Homo sapiens	45-63
16855054-9	2006	Results of CE metabolism revealed that human carboxylesterase 1 (hCE-1) was markedly more active toward deltamethrin than the class 1 rat CEs hydrolase A and B and the class 2 human CE (hCE-2); however, hydrolase A metabolized esfenvalerate 2-fold faster than hCE-1, whereas hydrolase B and hCE-1 hydrolyzed esfenvalerate at equal rates.	fenvalerate	308-321	carboxylesterase 1	Homo sapiens	65-70
16626760-5	2006	In our model, fifteen of the tested pesticides were found to agonize the ERalpha-mediated transcription in a dose-dependent manner and DDT, trans-nonachlor, chlordane, fenvalerate and toxaphene were also capable to activate ERbeta.	fenvalerate	168-179	estrogen receptor 2	Homo sapiens	224-230
16326432-8	2005	However, PR protein levels were not affected in T47D cells cultured with fenvalerate and permethrin alone, whereas fenvalerate and permethrin significantly decreased progesterone-induced PR protein levels.	fenvalerate	115-126	progesterone receptor	Homo sapiens	187-189
16673813-10	2006	The activities of phosphorylase a enhanced in all treated groups, and fenvalerate increased the total content of calmodulin significantly in estrus period.	fenvalerate	70-81	calmodulin 1	Rattus norvegicus	113-123
16125883-0	2006	Androgen receptor activities of p,p"-DDE, fenvalerate and phoxim detected by androgen receptor reporter gene assay.	fenvalerate	42-53	androgen receptor	Homo sapiens	0-17
16125883-7	2006	Fenvalerate acted as weak AR antagonist and phoxim did not show AR antagonistic activity.	fenvalerate	0-11	androgen receptor	Homo sapiens	26-28
16167828-9	2005	These clashes appeared to explain the stereopreference between trans- and cis-isomers of cypermethrin analogues, and the 2R- and 2S-isomers of fenvalerate analogues by hCE1.	fenvalerate	143-154	carboxylesterase 1	Homo sapiens	168-172
15907653-8	2005	Fenvalerate reduced mRNA and protein expression of P450scc.	fenvalerate	0-11	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	51-58
12396874-7	2002	Fenvalerate, permethrin, and cypermethrin induced pS2 mRNA expression with varying potency, while there were no significant effects in deltamethrin-treated groups.	fenvalerate	0-11	taste 2 receptor member 64 pseudogene	Homo sapiens	50-53
16001830-7	2005	RT-PCR revealed that fenvalerate had no significant effect on 3 beta-HSD, but could increase the P450scc mRNA level.	fenvalerate	21-32	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	97-104
16001830-8	2005	In addition, 17 beta-HSD mRNA level was dramatically reduced with the increase of fenvalerate dose after 24 h treatment.	fenvalerate	82-93	hydroxysteroid (17-beta) dehydrogenase 3	Rattus norvegicus	13-24
15799245-4	2005	In the present study, the influence of both fenvalerate and phoxim was examined on the expression of JWA in MCF-7 (ER+) and MDA-MB-231 (ER-) human breast carcinoma cell lines.	fenvalerate	44-55	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	101-104
15799245-8	2005	The results showed that after treatment with fenvalerate, both JWA and hsp70 showed similar expression patterns in the both cell lines; however, all the expression patterns of JWA, hsp27, and hsp70 were evidently reversed between ER+ and ER- cells.	fenvalerate	45-56	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	63-66
15799245-8	2005	The results showed that after treatment with fenvalerate, both JWA and hsp70 showed similar expression patterns in the both cell lines; however, all the expression patterns of JWA, hsp27, and hsp70 were evidently reversed between ER+ and ER- cells.	fenvalerate	45-56	heat shock protein family A (Hsp70) member 4	Homo sapiens	71-76
15799245-8	2005	The results showed that after treatment with fenvalerate, both JWA and hsp70 showed similar expression patterns in the both cell lines; however, all the expression patterns of JWA, hsp27, and hsp70 were evidently reversed between ER+ and ER- cells.	fenvalerate	45-56	ADP ribosylation factor like GTPase 6 interacting protein 5	Homo sapiens	176-179
15799245-8	2005	The results showed that after treatment with fenvalerate, both JWA and hsp70 showed similar expression patterns in the both cell lines; however, all the expression patterns of JWA, hsp27, and hsp70 were evidently reversed between ER+ and ER- cells.	fenvalerate	45-56	heat shock protein family B (small) member 1	Homo sapiens	181-186
15799245-8	2005	The results showed that after treatment with fenvalerate, both JWA and hsp70 showed similar expression patterns in the both cell lines; however, all the expression patterns of JWA, hsp27, and hsp70 were evidently reversed between ER+ and ER- cells.	fenvalerate	45-56	heat shock protein family A (Hsp70) member 4	Homo sapiens	192-197
15389122-9	2004	DNA sequencing of the propositus and his mother revealed a new unique point mutation that gives rise to a fibrinogen molecule with a missing amino acid residue at Aalpha-Asn 80.	fenvalerate	163-170	fibrinogen beta chain	Homo sapiens	106-116
14769548-5	2004	In contrast, the type II pyrethroids deltamethrin and fenvalerate evoked direct depolarization of Na(v)1.8-F-11 and Na(v)1.5-293-EBNA cells.	fenvalerate	54-65	neuron navigator 1	Rattus norvegicus	98-104
14769548-5	2004	In contrast, the type II pyrethroids deltamethrin and fenvalerate evoked direct depolarization of Na(v)1.8-F-11 and Na(v)1.5-293-EBNA cells.	fenvalerate	54-65	sodium voltage-gated channel alpha subunit 5	Rattus norvegicus	116-124
12437293-4	2002	Two pyrethroid insecticides, sumithrin and fenvalerate, have been shown to mimic estrogenic activity in MCF-7 human breast carcinoma cells by inducing pS2 expression whereas two other pyrethroids, permethrin and d-trans allethrin do not have the same capability.	fenvalerate	43-54	taste 2 receptor member 64 pseudogene	Homo sapiens	151-154
12437293-9	2002	When compared to the solvent-treated controls, sumithrin, fenvalerate and estrogen treated MCF-7 cells all had increased levels of WNT10B expression.	fenvalerate	58-69	Wnt family member 10B	Homo sapiens	131-137
12052007-4	2002	In the present study, we evaluated the interaction of three pyrethroids (esfenvalerate, fenvalerate, and permethrin) with androgen receptor (AR)- and estrogen receptor (ER)-mediated mechanisms using in vivo short-term assays.	fenvalerate	73-86	estrogen receptor 1	Rattus norvegicus	150-167
12052007-4	2002	In the present study, we evaluated the interaction of three pyrethroids (esfenvalerate, fenvalerate, and permethrin) with androgen receptor (AR)- and estrogen receptor (ER)-mediated mechanisms using in vivo short-term assays.	fenvalerate	73-86	estrogen receptor 1	Rattus norvegicus	169-171
12052007-4	2002	In the present study, we evaluated the interaction of three pyrethroids (esfenvalerate, fenvalerate, and permethrin) with androgen receptor (AR)- and estrogen receptor (ER)-mediated mechanisms using in vivo short-term assays.	fenvalerate	73-86	androgen receptor	Rattus norvegicus	122-139
12052007-4	2002	In the present study, we evaluated the interaction of three pyrethroids (esfenvalerate, fenvalerate, and permethrin) with androgen receptor (AR)- and estrogen receptor (ER)-mediated mechanisms using in vivo short-term assays.	fenvalerate	73-86	androgen receptor	Rattus norvegicus	141-143
12052007-4	2002	In the present study, we evaluated the interaction of three pyrethroids (esfenvalerate, fenvalerate, and permethrin) with androgen receptor (AR)- and estrogen receptor (ER)-mediated mechanisms using in vivo short-term assays.	fenvalerate	75-86	androgen receptor	Rattus norvegicus	122-139
12052007-4	2002	In the present study, we evaluated the interaction of three pyrethroids (esfenvalerate, fenvalerate, and permethrin) with androgen receptor (AR)- and estrogen receptor (ER)-mediated mechanisms using in vivo short-term assays.	fenvalerate	75-86	androgen receptor	Rattus norvegicus	141-143
12052007-4	2002	In the present study, we evaluated the interaction of three pyrethroids (esfenvalerate, fenvalerate, and permethrin) with androgen receptor (AR)- and estrogen receptor (ER)-mediated mechanisms using in vivo short-term assays.	fenvalerate	75-86	estrogen receptor 1	Rattus norvegicus	150-167
12052007-4	2002	In the present study, we evaluated the interaction of three pyrethroids (esfenvalerate, fenvalerate, and permethrin) with androgen receptor (AR)- and estrogen receptor (ER)-mediated mechanisms using in vivo short-term assays.	fenvalerate	75-86	estrogen receptor 1	Rattus norvegicus	169-171
11377398-2	2001	In this project, we examined the influence of pyrethroids (permethrin, cypermethrin, and fenvalerate) on the expression and activity of the phenobarbital (PB)-inducible cytochrome P450 2B1 isoform (CYP2B1) in primary rat hepatocyte cultures.	fenvalerate	89-100	cytochrome P450 2B1	Rattus norvegicus	169-188
11377398-2	2001	In this project, we examined the influence of pyrethroids (permethrin, cypermethrin, and fenvalerate) on the expression and activity of the phenobarbital (PB)-inducible cytochrome P450 2B1 isoform (CYP2B1) in primary rat hepatocyte cultures.	fenvalerate	89-100	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	198-204
10064545-5	1999	Nanomolar concentrations of either sumithrin or fenvalerate were sufficient to increase pS2 expression slightly above basal levels.	fenvalerate	48-59	taste 2 receptor member 64 pseudogene	Homo sapiens	88-91