PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
24911634-8	2014	Pretreatment with irestatin 9389, salubrinal, or AEBSF also blocked ox-LDL-induced expression of CHOP and Bcl-2 and activation of caspase-12 activity, leading to an attenuation of endothelial cell apoptosis.	irestatin	18-27	DNA damage inducible transcript 3	Homo sapiens	97-101
24911634-8	2014	Pretreatment with irestatin 9389, salubrinal, or AEBSF also blocked ox-LDL-induced expression of CHOP and Bcl-2 and activation of caspase-12 activity, leading to an attenuation of endothelial cell apoptosis.	irestatin	18-27	BCL2 apoptosis regulator	Homo sapiens	106-111
23583400-6	2013	This effect was significantly depressed by the AT1R blocker losartan and different inhibitors (irestatin, IRE1 specific inhibitor; SP600125, JNK specific inhibitor; SB203580, p38 MAPK specific inhibitor) but not by the AT2R blocker PD123319.	irestatin	95-104	angiotensin II receptor type 1	Homo sapiens	47-51
23583400-10	2013	The IRE1 specific inhibitor irestatin, the JNK specific inhibitor SP600125, and the p38 MAPK specific inhibitor SB203580 significantly inhibited Ang II-induced capillary formation from endothelial cells and VEGF expression but had no effect on GRP78.	irestatin	28-37	endoplasmic reticulum to nucleus signaling 1	Homo sapiens	4-8
23583400-10	2013	The IRE1 specific inhibitor irestatin, the JNK specific inhibitor SP600125, and the p38 MAPK specific inhibitor SB203580 significantly inhibited Ang II-induced capillary formation from endothelial cells and VEGF expression but had no effect on GRP78.	irestatin	28-37	vascular endothelial growth factor A	Homo sapiens	207-211