PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 29487008-9 2018 Combining TB and PDC grades into single grading system (high-grade: Bd3 + G2, Bd2 + G3, Bd3 + G3; low-grade: other combinations) was found to have strong correlation with both 5-year DSS and OS (both p < 0.001). Terbium 10-12 defensin beta 103B Homo sapiens 68-71 29487008-9 2018 Combining TB and PDC grades into single grading system (high-grade: Bd3 + G2, Bd2 + G3, Bd3 + G3; low-grade: other combinations) was found to have strong correlation with both 5-year DSS and OS (both p < 0.001). Terbium 10-12 defensin beta 4A Homo sapiens 78-81 29487008-9 2018 Combining TB and PDC grades into single grading system (high-grade: Bd3 + G2, Bd2 + G3, Bd3 + G3; low-grade: other combinations) was found to have strong correlation with both 5-year DSS and OS (both p < 0.001). Terbium 10-12 defensin beta 103B Homo sapiens 88-91 29489879-10 2018 CONCLUSION: Phenotypic enumeration of peripheral CD4+CD25+FOXP3+ Treg cells can be used as a non-invasive biomarker in clinics with a high diagnostic accuracy to differentiate between ITB and CD in regions where TB is endemic. Terbium 185-187 CD4 molecule Homo sapiens 49-52 29489879-10 2018 CONCLUSION: Phenotypic enumeration of peripheral CD4+CD25+FOXP3+ Treg cells can be used as a non-invasive biomarker in clinics with a high diagnostic accuracy to differentiate between ITB and CD in regions where TB is endemic. Terbium 185-187 interleukin 2 receptor subunit alpha Homo sapiens 53-57 29489879-10 2018 CONCLUSION: Phenotypic enumeration of peripheral CD4+CD25+FOXP3+ Treg cells can be used as a non-invasive biomarker in clinics with a high diagnostic accuracy to differentiate between ITB and CD in regions where TB is endemic. Terbium 185-187 forkhead box P3 Homo sapiens 58-63 29359915-5 2018 The resulting Tb@UiO-66-Hybrid film exhibited good temperature-sensing properties with a relative sensitivity of up to 2.76% K-1 in the temperature range of 303-353 K. In addition, the Eu@UiO-66-Hybrid film showed excellent temperature-sensing performance based on the energy transfer between the luminescent ligand (H2NDC) and europium ions with a relative sensitivity of up to 4.26% K-1 in the temperature range of 303-403 K. Terbium 14-16 keratin 1 Homo sapiens 125-128 29359915-5 2018 The resulting Tb@UiO-66-Hybrid film exhibited good temperature-sensing properties with a relative sensitivity of up to 2.76% K-1 in the temperature range of 303-353 K. In addition, the Eu@UiO-66-Hybrid film showed excellent temperature-sensing performance based on the energy transfer between the luminescent ligand (H2NDC) and europium ions with a relative sensitivity of up to 4.26% K-1 in the temperature range of 303-403 K. Terbium 14-16 keratin 1 Homo sapiens 385-388 29283575-8 2018 This analysis found all three TB-DiPhOBz analogues to be potential ligands for gull TTR and have similar binding efficacies to THs. Terbium 30-32 transthyretin Homo sapiens 84-87 29235156-10 2018 The study shows that IFN-gamma against the 38 kDa discriminates clinical TB from infection and infection from exposure, suggesting its potential for immune protection and diagnosis. Terbium 73-75 interferon gamma Homo sapiens 21-30 29274493-3 2018 This study aimed to develop selective M. tuberculosis DHFR inhibitors using rationale scaffolding design and synthesis, phenotype-oriented screening, enzymatic inhibitory study, whole cell on-target validation, molecular modeling, and in vitro DMPK determination to derive new anti-TB agents. Terbium 282-284 dihydrofolate reductase Homo sapiens 54-58 29219243-8 2018 While in the subgroup of new TB cases, DRB1*08:01 (p < .0001; OR = 80.3, 95% CI 7.0-917.1) and older age (p < .0001; OR = 3.9, 95% CI 2.4-6.4) were independent susceptibility factors for primary MDR/RR-TB. Terbium 29-31 major histocompatibility complex, class II, DR beta 1 Homo sapiens 39-43 29136358-0 2018 Is secretion of IFN-gamma in response to Mycobacterium tuberculosis antigens in youngest children sufficient to play a role in TB diagnostics? Terbium 127-129 interferon gamma Homo sapiens 16-25 29136358-2 2018 WORKING HYPOTHESIS: Is TB-antigen-induced IFN-gamma response in children <=5 years sufficient to consider QFT-GIT a possible tool for TB diagnostics? Terbium 23-25 interferon gamma Homo sapiens 42-51 29136358-6 2018 In the mitogen tubes, the median IFN-gamma level was higher in children >5 years (median 17.87, IQR:2.1 vs 16.77, IQR:7.6), but surprisingly in the TB antigen tubes it was higher in the younger group (median 0.12, IQR:0.21vs 0.06, IQR:0.09, P = 0.04). Terbium 151-153 interferon gamma Homo sapiens 33-42 29136358-9 2018 CONCLUSIONS: The youngest children release sufficient amount of IFN-gamma in response to TB antigens thus QFT-GIT might be a useful tool for TB diagnostics in this age group. Terbium 89-91 interferon gamma Homo sapiens 64-73 29136358-9 2018 CONCLUSIONS: The youngest children release sufficient amount of IFN-gamma in response to TB antigens thus QFT-GIT might be a useful tool for TB diagnostics in this age group. Terbium 141-143 interferon gamma Homo sapiens 64-73 29274493-2 2018 Dihydrofolate reductase (DHFR) has recently attracted much attention as a target for the development of anti-TB agents. Terbium 109-111 dihydrofolate reductase Homo sapiens 25-29 29686176-4 2018 Therefore it is necessary to uncovered the existence and association between Arg753Gln and Arg677Trp TLR2 gene polymorphism with TB susceptibility and its underlying mechanisms in Indonesian population in Bandung West Java. Terbium 129-131 toll like receptor 2 Homo sapiens 101-105 29686176-9 2018 RESULTS: heterozygote Arg753Gln TLR2 gene polymorphism was found in 9 of 86 pulmonary TB subjects (10.5%) but none in the latent TB group. Terbium 86-88 toll like receptor 2 Homo sapiens 32-36 29686176-9 2018 RESULTS: heterozygote Arg753Gln TLR2 gene polymorphism was found in 9 of 86 pulmonary TB subjects (10.5%) but none in the latent TB group. Terbium 129-131 toll like receptor 2 Homo sapiens 32-36 29686176-13 2018 Conlusion: Arg753Gln polymorphism of TLR2 gene is a risk factor for active pulmonary TB while Arg677Trp polymorphism is not. Terbium 85-87 toll like receptor 2 Homo sapiens 37-41 29124333-10 2018 Results of the study proved increased hepatotoxicity due to combinational treatment of anti-TB drugs and also that CYP2E1, NR1I2, NAT, and CYP7A1 genes play a vital role in anti-TB drug-induced hepatotoxicity. Terbium 92-94 nuclear receptor subfamily 1, group I, member 2 Rattus norvegicus 123-128 29124333-10 2018 Results of the study proved increased hepatotoxicity due to combinational treatment of anti-TB drugs and also that CYP2E1, NR1I2, NAT, and CYP7A1 genes play a vital role in anti-TB drug-induced hepatotoxicity. Terbium 92-94 N-acetyltransferase 1 Rattus norvegicus 130-133 29124333-10 2018 Results of the study proved increased hepatotoxicity due to combinational treatment of anti-TB drugs and also that CYP2E1, NR1I2, NAT, and CYP7A1 genes play a vital role in anti-TB drug-induced hepatotoxicity. Terbium 92-94 cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus 139-145 29124333-10 2018 Results of the study proved increased hepatotoxicity due to combinational treatment of anti-TB drugs and also that CYP2E1, NR1I2, NAT, and CYP7A1 genes play a vital role in anti-TB drug-induced hepatotoxicity. Terbium 178-180 cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus 115-121 29124333-10 2018 Results of the study proved increased hepatotoxicity due to combinational treatment of anti-TB drugs and also that CYP2E1, NR1I2, NAT, and CYP7A1 genes play a vital role in anti-TB drug-induced hepatotoxicity. Terbium 178-180 nuclear receptor subfamily 1, group I, member 2 Rattus norvegicus 123-128 29124333-10 2018 Results of the study proved increased hepatotoxicity due to combinational treatment of anti-TB drugs and also that CYP2E1, NR1I2, NAT, and CYP7A1 genes play a vital role in anti-TB drug-induced hepatotoxicity. Terbium 178-180 N-acetyltransferase 1 Rattus norvegicus 130-133 29124333-10 2018 Results of the study proved increased hepatotoxicity due to combinational treatment of anti-TB drugs and also that CYP2E1, NR1I2, NAT, and CYP7A1 genes play a vital role in anti-TB drug-induced hepatotoxicity. Terbium 178-180 cytochrome P450 family 7 subfamily A member 1 Rattus norvegicus 139-145 29084410-6 2018 CONCLUSIONS: In men with increased serum PSA and/or abnormal DRE and suspicious lesion on MRI but non-previous evidence of PCa, 3D-Tb plus Sb improves the PCa detection rate based on Sb alone. Terbium 131-133 aminopeptidase puromycin sensitive Homo sapiens 41-44 29211755-11 2017 CONCLUSIONS: Xpert MTB/RIF test is a valid diagnostic technique for TBP with higher sensitivity and specificity than T-SPOT.TB. Terbium 20-22 TATA-box binding protein Homo sapiens 68-71 29281719-8 2017 A significant increase in mCD14 expression and serum sCD14 levels was found in TB group. Terbium 79-81 CD14 antigen Mus musculus 26-31 29222466-2 2017 Therefore, we carried out a global and unbiased analysis on previously published transcriptomic profiles for hESC differentiated to TB by means of bone morphogenetic protein-4 and inhibitors of activin A and fibroblast growth factor-2 signaling (BAP treatment). Terbium 132-134 bone morphogenetic protein 4 Homo sapiens 147-175 28686305-5 2017 The number of oxygen atoms segregating in a unit TB area NGB (in atoms nm-2 ) was determined to be proportional to both the number of the atomic sites under tensile stress in a unit TB area nbc and the average concentration of oxygen atoms around the TB [Oi ] (in at.%) with NGB ~ 50 nbc [Oi ]. Terbium 49-51 neuroglobin Homo sapiens 57-60 29664036-5 2017 Results: The level of CCL5 decreased significantly in patients who were on therapy/completed their therapy [inactive TB patient/inactive PTB (IPTB)], particularly with AA genotype of -403G>A (P=0.046). Terbium 117-119 C-C motif chemokine ligand 5 Homo sapiens 22-26 29664036-7 2017 Similarly, the CCL5 level was found to be higher in sputum-positive/active TB patients than in IPTB group and healthy controls. Terbium 75-77 C-C motif chemokine ligand 5 Homo sapiens 15-19 28686305-5 2017 The number of oxygen atoms segregating in a unit TB area NGB (in atoms nm-2 ) was determined to be proportional to both the number of the atomic sites under tensile stress in a unit TB area nbc and the average concentration of oxygen atoms around the TB [Oi ] (in at.%) with NGB ~ 50 nbc [Oi ]. Terbium 49-51 neuroglobin Homo sapiens 275-278 28971232-0 2017 Terbium chelation, a specific fluorescent tagging of human transferrin. Terbium 0-7 transferrin Homo sapiens 59-70 29077389-9 2017 The "luminescence-on" behavior of l-Y(OH)3:Ce,Tb by phosphate adsorption was employed to detect and recover phosphorus at low concentrations in deionized water, mineral water, tap water, and river water. Terbium 46-48 nuclear RNA export factor 1 Homo sapiens 176-179 28971232-14 2017 Graphical abstract Schematic representation of HPLC-separated transferrin glycoforms detected by fluorescence emission of the terbium ions bound to the protein. Terbium 126-133 transferrin Homo sapiens 62-73 32264370-2 2017 The self-adaptive assembly of terbium ions (Tb3+), adenosine monophosphate (AMP), glucose oxidase (GOx), and carbon dots (CDs) leads to the formation of a GOx&CDs@AMP/Tb composite with catalytic and fluorescence properties. Terbium 30-37 hydroxyacid oxidase 1 Homo sapiens 82-97 29025477-0 2017 TB stigma: clearing the fog. Terbium 0-2 zinc finger protein, FOG family member 1 Homo sapiens 24-27 28741242-3 2017 The aim of this study was to examine if sEH inhibition affects core body temperature (Tb) as well as Tb changes during febrile response to infectious (lipopolysaccharide; LPS) or non-infectious (turpentine; TRP) stimuli. Terbium 86-88 epoxide hydrolase 2 Rattus norvegicus 40-43 29109952-0 2017 Is TB Testing Associated With Increased Blood Interferon-Gamma Levels? Terbium 3-5 interferon gamma Bos taurus 46-62 29059214-15 2017 Two poor quality studies reported the effect of insulin on TB treatment outcomes. Terbium 59-61 insulin Homo sapiens 48-55 32264370-2 2017 The self-adaptive assembly of terbium ions (Tb3+), adenosine monophosphate (AMP), glucose oxidase (GOx), and carbon dots (CDs) leads to the formation of a GOx&CDs@AMP/Tb composite with catalytic and fluorescence properties. Terbium 30-37 hydroxyacid oxidase 1 Homo sapiens 99-102 32264370-2 2017 The self-adaptive assembly of terbium ions (Tb3+), adenosine monophosphate (AMP), glucose oxidase (GOx), and carbon dots (CDs) leads to the formation of a GOx&CDs@AMP/Tb composite with catalytic and fluorescence properties. Terbium 30-37 hydroxyacid oxidase 1 Homo sapiens 155-158 32264370-2 2017 The self-adaptive assembly of terbium ions (Tb3+), adenosine monophosphate (AMP), glucose oxidase (GOx), and carbon dots (CDs) leads to the formation of a GOx&CDs@AMP/Tb composite with catalytic and fluorescence properties. Terbium 44-46 hydroxyacid oxidase 1 Homo sapiens 82-97 32264370-2 2017 The self-adaptive assembly of terbium ions (Tb3+), adenosine monophosphate (AMP), glucose oxidase (GOx), and carbon dots (CDs) leads to the formation of a GOx&CDs@AMP/Tb composite with catalytic and fluorescence properties. Terbium 44-46 hydroxyacid oxidase 1 Homo sapiens 155-158 32264370-3 2017 Owing to the confinement effect, the GOx&CDs@AMP/Tb composite exhibited about 2-fold higher catalytic activity than free GOx. Terbium 49-51 hydroxyacid oxidase 1 Homo sapiens 37-40 32264370-3 2017 Owing to the confinement effect, the GOx&CDs@AMP/Tb composite exhibited about 2-fold higher catalytic activity than free GOx. Terbium 49-51 hydroxyacid oxidase 1 Homo sapiens 121-124 32264370-5 2017 On this basis, by considering the advantages of carboxyphenylboronic acid (CPBA) in the sensitization of Tb3+ fluorescence and specific recognition of hydrogen peroxide, a dual-emissive GOx&CDs@AMP/Tb-CPBA composite was further fabricated for the ratiometric sensing of glucose. Terbium 105-107 hydroxyacid oxidase 1 Homo sapiens 186-189 28652188-9 2017 Analysis of correlation revealed a positive and significant association between density of CGRP+ or TH+ nerve fibers with tBMD, BV/TV, Tb.Th and Tb.Sp, but not with trabecular number (there was a positive association only for CGRP+) and degree of anisotropy (DA). Terbium 135-137 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 91-95 29348383-13 2017 CONCLUSION: Bronchoalveolar lavage can improve the positivity level of smears and cultures in patients suspected of pulmonary TB in HIV patients with CD4<200 cells/muL. Terbium 126-128 tripartite motif containing 37 Homo sapiens 167-170 29171455-2 2017 To find the meaning of cytochrome P-4502E1 (CYP2E1) polymorphism in TB patients. Terbium 68-70 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 23-42 29171455-2 2017 To find the meaning of cytochrome P-4502E1 (CYP2E1) polymorphism in TB patients. Terbium 68-70 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 44-50 29171455-3 2017 Corresponding of CYP2E1 polymorphism in TB patients with the level of isoniazid and rifampicin as well as for the outcome and toxicity development during inpatient TB treatment. Terbium 40-42 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 17-23 29171455-11 2017 CONCLUSION: Polymorphism of CYP2E1 genotype is an important criterion for the development of hepatotoxicity before and during TB treatment while increased rifampicin level has no influence on it. Terbium 126-128 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 28-34 28875602-7 2017 E-cadherin and EpCAM displayed a tendency to be found along the cell membrane in TC samples (91.5% and 92.3%, respectively), whereas they showed loss of membranous staining in PDC (44.4% and 36.8%, respectively) and TB samples (60.7% and 68.4%, respectively). Terbium 216-218 cadherin 1 Homo sapiens 0-10 28875602-7 2017 E-cadherin and EpCAM displayed a tendency to be found along the cell membrane in TC samples (91.5% and 92.3%, respectively), whereas they showed loss of membranous staining in PDC (44.4% and 36.8%, respectively) and TB samples (60.7% and 68.4%, respectively). Terbium 216-218 epithelial cell adhesion molecule Homo sapiens 15-20 28875602-8 2017 An inside-out pattern for MUC1 and EMA was frequently observed in PDC (48.7% and 45.3%, respectively) and TB samples (46.2% and 45.3%, respectively), but not in TC samples. Terbium 106-108 mucin 1, cell surface associated Homo sapiens 26-30 28875602-8 2017 An inside-out pattern for MUC1 and EMA was frequently observed in PDC (48.7% and 45.3%, respectively) and TB samples (46.2% and 45.3%, respectively), but not in TC samples. Terbium 106-108 mucin 1, cell surface associated Homo sapiens 35-38 28165653-8 2017 RESULTS: TB compared with SB had higher CDR for SPCa (45%, 72/161 vs. 39%, 63/161, respectively; P > 0.05) and a lower CDR for Gleason score 3 + 3 (8%, 15/161 vs. 16%, 30/161; P < 0.05). Terbium 9-11 coagulation factor VII Homo sapiens 48-52 29082358-7 2017 The miR17~92 osteoclast conditional knockout (cKO) mutants, generated by breeding miR17~92loxp/loxp mice with Ctsk-Cre mice, had lower Tb.BV/TV, Tb.BMD, Tb.Conn-Dens, Tb.N, and Tb.Th, but larger Tb.Sp, and greater bone resorption without a change in bone formation compared to littermate controls. Terbium 135-137 Mir17 host gene (non-protein coding) Mus musculus 4-12 29082358-7 2017 The miR17~92 osteoclast conditional knockout (cKO) mutants, generated by breeding miR17~92loxp/loxp mice with Ctsk-Cre mice, had lower Tb.BV/TV, Tb.BMD, Tb.Conn-Dens, Tb.N, and Tb.Th, but larger Tb.Sp, and greater bone resorption without a change in bone formation compared to littermate controls. Terbium 135-137 Mir17 host gene (non-protein coding) Mus musculus 4-9 29082358-7 2017 The miR17~92 osteoclast conditional knockout (cKO) mutants, generated by breeding miR17~92loxp/loxp mice with Ctsk-Cre mice, had lower Tb.BV/TV, Tb.BMD, Tb.Conn-Dens, Tb.N, and Tb.Th, but larger Tb.Sp, and greater bone resorption without a change in bone formation compared to littermate controls. Terbium 145-147 Mir17 host gene (non-protein coding) Mus musculus 4-12 29082358-7 2017 The miR17~92 osteoclast conditional knockout (cKO) mutants, generated by breeding miR17~92loxp/loxp mice with Ctsk-Cre mice, had lower Tb.BV/TV, Tb.BMD, Tb.Conn-Dens, Tb.N, and Tb.Th, but larger Tb.Sp, and greater bone resorption without a change in bone formation compared to littermate controls. Terbium 145-147 Mir17 host gene (non-protein coding) Mus musculus 4-9 29082358-7 2017 The miR17~92 osteoclast conditional knockout (cKO) mutants, generated by breeding miR17~92loxp/loxp mice with Ctsk-Cre mice, had lower Tb.BV/TV, Tb.BMD, Tb.Conn-Dens, Tb.N, and Tb.Th, but larger Tb.Sp, and greater bone resorption without a change in bone formation compared to littermate controls. Terbium 145-147 Mir17 host gene (non-protein coding) Mus musculus 4-12 29082358-7 2017 The miR17~92 osteoclast conditional knockout (cKO) mutants, generated by breeding miR17~92loxp/loxp mice with Ctsk-Cre mice, had lower Tb.BV/TV, Tb.BMD, Tb.Conn-Dens, Tb.N, and Tb.Th, but larger Tb.Sp, and greater bone resorption without a change in bone formation compared to littermate controls. Terbium 145-147 Mir17 host gene (non-protein coding) Mus musculus 4-9 29082358-7 2017 The miR17~92 osteoclast conditional knockout (cKO) mutants, generated by breeding miR17~92loxp/loxp mice with Ctsk-Cre mice, had lower Tb.BV/TV, Tb.BMD, Tb.Conn-Dens, Tb.N, and Tb.Th, but larger Tb.Sp, and greater bone resorption without a change in bone formation compared to littermate controls. Terbium 145-147 Mir17 host gene (non-protein coding) Mus musculus 4-12 29082358-7 2017 The miR17~92 osteoclast conditional knockout (cKO) mutants, generated by breeding miR17~92loxp/loxp mice with Ctsk-Cre mice, had lower Tb.BV/TV, Tb.BMD, Tb.Conn-Dens, Tb.N, and Tb.Th, but larger Tb.Sp, and greater bone resorption without a change in bone formation compared to littermate controls. Terbium 145-147 Mir17 host gene (non-protein coding) Mus musculus 4-9 29057044-2 2017 It demonstrates excellent efficacy against TB but induces phospholipidosis at high doses, has a long terminal elimination half-life (due to its high lipophilicity), and exhibits potent hERG channel inhibition, resulting in clinical QTc interval prolongation. Terbium 43-45 ETS transcription factor ERG Homo sapiens 185-189 28351806-12 2017 Our results showed the strongest significant positive associations for IL-6 with MI, ST and TB in elderly people. Terbium 92-94 interleukin 6 Homo sapiens 71-75 29100330-7 2017 CD4-low PBMCs from HIV and TB co-infected patients recognized ROP-CFP10-ESAT6 compared to a soluble form of the antigen. Terbium 27-29 CD4 molecule Homo sapiens 0-3 28821804-3 2017 We found that Nos2 -/- mice incapable of NO-production in immune cells as microbial defence uniformly develop hypoxic necrotizing lung lesions, widely observed in human TB. Terbium 169-171 nitric oxide synthase 2, inducible Mus musculus 14-18 28821804-8 2017 Linezolid was bacteriostatic in TB-infected Nos2 -/- mice but significantly improved lung pathology. Terbium 32-34 nitric oxide synthase 2, inducible Mus musculus 44-48 28821804-10 2017 In conclusion, Nos2 -/- mice are a predictive TB drug development tool owing to their consistent development of human-like pathology. Terbium 46-48 nitric oxide synthase 2, inducible Mus musculus 15-19 29022528-10 2017 CONCLUSION: GeneXpert MTB/RIF is an accurate test for the detection of TB in tissue samples of HIV-infected and HIV-uninfected patients with suspected musculoskeletal TB. Terbium 71-73 ras homolog family member F, filopodia associated Homo sapiens 26-29 28827363-8 2017 Targeted IGF-1R knockout selectively in forebrain neurons revealed that IGF signaling also modulates calorie restriction-dependent Tb regulation in regions rostral of the canonical hypothalamic nuclei involved in controlling body temperature. Terbium 131-133 insulin-like growth factor I receptor Mus musculus 9-15 28652188-9 2017 Analysis of correlation revealed a positive and significant association between density of CGRP+ or TH+ nerve fibers with tBMD, BV/TV, Tb.Th and Tb.Sp, but not with trabecular number (there was a positive association only for CGRP+) and degree of anisotropy (DA). Terbium 135-137 calcitonin/calcitonin-related polypeptide, alpha Mus musculus 91-96 28655638-7 2017 TB is associated with poor prognosis in ER+/HER2- and TNBC cancer. Terbium 0-2 erb-b2 receptor tyrosine kinase 2 Homo sapiens 44-48 28759590-5 2017 In contrast, the cytokine profile of Mtb-specific CD4 T cells of TB patients from SA was dominated by single IFN-gamma and dual IFN-gamma/TNF-alpha and associated with TB-induced systemic inflammation and elevated serum levels of type I IFNs. Terbium 65-67 CD4 molecule Homo sapiens 50-53 28759590-5 2017 In contrast, the cytokine profile of Mtb-specific CD4 T cells of TB patients from SA was dominated by single IFN-gamma and dual IFN-gamma/TNF-alpha and associated with TB-induced systemic inflammation and elevated serum levels of type I IFNs. Terbium 65-67 interferon gamma Homo sapiens 109-118 28759590-5 2017 In contrast, the cytokine profile of Mtb-specific CD4 T cells of TB patients from SA was dominated by single IFN-gamma and dual IFN-gamma/TNF-alpha and associated with TB-induced systemic inflammation and elevated serum levels of type I IFNs. Terbium 65-67 interferon gamma Homo sapiens 128-137 28759590-5 2017 In contrast, the cytokine profile of Mtb-specific CD4 T cells of TB patients from SA was dominated by single IFN-gamma and dual IFN-gamma/TNF-alpha and associated with TB-induced systemic inflammation and elevated serum levels of type I IFNs. Terbium 65-67 tumor necrosis factor Homo sapiens 138-147 28743860-5 2017 Variants in the TOM1L2/SREBF1 locus exert opposing effects TB-LM and TBLH-BMD, and have a stronger association with the former trait. Terbium 59-61 target of myb1 like 2 membrane trafficking protein Homo sapiens 16-22 28743860-5 2017 Variants in the TOM1L2/SREBF1 locus exert opposing effects TB-LM and TBLH-BMD, and have a stronger association with the former trait. Terbium 59-61 sterol regulatory element binding transcription factor 1 Homo sapiens 23-29 28693508-12 2017 CONCLUSIONS: The importance of TB-HIV/AIDS treatment integration is evident as co-infected patients on both ART and CPT, and those who have a higher CD4 count are less likely to have an unsuccessful TB treatment outcome. Terbium 31-33 CD4 molecule Homo sapiens 149-152 28438617-6 2017 To assess the prognostic value of TB in pT1 CRCs, this meta-analysis evaluated 41 studies involving a total of 10137 patients. Terbium 34-36 zinc finger protein 77 Homo sapiens 40-43 28438617-7 2017 We observed a strong association between the presence of TB and risk of nodal metastasis in pT1 CRC. Terbium 57-59 zinc finger protein 77 Homo sapiens 92-95 28438617-10 2017 These results support the priority of histologically reporting TB in any endoscopically removed pT1 CRC to direct more appropriate patient management. Terbium 63-65 zinc finger protein 77 Homo sapiens 96-99 28614380-6 2017 In addition, the clinical parameters analysis found that serum IL-34 was significantly associated with HBV DNA (P = 0.0066), ALT (P = 0.0327), AST (P = 0.0435), TB (P = 0.0406), DB (P = 0.0368) and AFP (P = 0.0225). Terbium 161-163 interleukin 34 Homo sapiens 63-68 27669189-11 2017 During the different BP modes, the SMBP and BBP elicited significantly greater TB activity vs. the DBP. Terbium 79-81 transmembrane 9 superfamily member 3 Homo sapiens 35-39 27669189-11 2017 During the different BP modes, the SMBP and BBP elicited significantly greater TB activity vs. the DBP. Terbium 79-81 transmembrane protein 158 Homo sapiens 44-47 27669189-13 2017 During the succeeding TE exercise, significantly greater activity of the TB was observed when this exercise was performed after the BBP vs. the SMBP and DBP. Terbium 73-75 transmembrane protein 158 Homo sapiens 132-135 27669189-13 2017 During the succeeding TE exercise, significantly greater activity of the TB was observed when this exercise was performed after the BBP vs. the SMBP and DBP. Terbium 73-75 transmembrane 9 superfamily member 3 Homo sapiens 144-148 27669189-13 2017 During the succeeding TE exercise, significantly greater activity of the TB was observed when this exercise was performed after the BBP vs. the SMBP and DBP. Terbium 73-75 D-box binding PAR bZIP transcription factor Homo sapiens 153-156 28610790-9 2017 Interestingly, low levels of miR-30c are specific for this active form of TB, as its expression is not altered in mononuclear cells from either healthy controls or patients with tuberculous or non-tuberculous pleurisy. Terbium 74-76 microRNA 30c-1 Homo sapiens 29-36 28610790-11 2017 In sum, our studies identify miR-30c as a specific correlate of pulmonary manifestations of TB, potentially involved in the altered glucocorticoid sensitivity observed in these patients. Terbium 92-94 microRNA 30c-1 Homo sapiens 29-36 28610793-9 2017 For detection of RIF resistance, the sensitivity and specificity of ML TB test were 89.2% and 95.7%, respectively. Terbium 71-73 ras homolog family member F, filopodia associated Homo sapiens 17-20 28610793-11 2017 ML TB test showed similar performance to Xpert MTB/RIF for detection of MTBC and RIF resistance. Terbium 3-5 ras homolog family member F, filopodia associated Homo sapiens 81-84 28856068-4 2017 We hypothesized that secretory levels of M. tuberculosis thymidylate kinase (TMKmt) can Designate ATBI from LTBI and no TB (NTB). Terbium 99-101 deoxythymidylate kinase Homo sapiens 57-75 28625041-0 2017 Energy regulation in newly diagnosed TB with chronic energy deficiency: free fatty acids and RBP4. Terbium 37-39 retinol binding protein 4 Homo sapiens 93-97 29743730-4 2017 Next, this model was applied to SMAP L3 TB data from Apr 2015 to Jul 2016. Terbium 40-42 kinesin associated protein 3 Homo sapiens 32-36 28570642-5 2017 In patients with confirmed pulmonary TB, PI3Kdelta expression was absent within granulomas. Terbium 37-39 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Homo sapiens 41-50 28249842-7 2017 Following standard antituberculosis (anti-TB) treatment, we observed alterations in the baseline and/or antigen-specific levels of IFN-gamma, TNF-alpha, IL-1beta, and IL-18. Terbium 42-44 interferon gamma Homo sapiens 131-140 28249842-7 2017 Following standard antituberculosis (anti-TB) treatment, we observed alterations in the baseline and/or antigen-specific levels of IFN-gamma, TNF-alpha, IL-1beta, and IL-18. Terbium 42-44 tumor necrosis factor Homo sapiens 142-151 28189712-8 2017 The most striking result was the significant decrease in IL-1Ra after 8 weeks of anti-TB treatment (median reduction: -63% (p < 0.0001)). Terbium 86-88 interleukin 1 receptor antagonist Homo sapiens 57-63 28189712-11 2017 The substantial reduction of IL-1Ra under treatment suggests that IL-1Ra could be a surrogate biomarker of anti-TB treatment response in HIV-infected patients. Terbium 112-114 interleukin 1 receptor antagonist Homo sapiens 29-35 28189712-11 2017 The substantial reduction of IL-1Ra under treatment suggests that IL-1Ra could be a surrogate biomarker of anti-TB treatment response in HIV-infected patients. Terbium 112-114 interleukin 1 receptor antagonist Homo sapiens 66-72 28477913-6 2017 The injection of TRPV4 agonist (GSK1016790A) in the POA decreased Tb while its antagonist (RN1734) increased Tb. Terbium 66-68 transient receptor potential cation channel, subfamily V, member 4 Rattus norvegicus 17-22 28477913-6 2017 The injection of TRPV4 agonist (GSK1016790A) in the POA decreased Tb while its antagonist (RN1734) increased Tb. Terbium 109-111 transient receptor potential cation channel, subfamily V, member 4 Rattus norvegicus 17-22 28254653-7 2017 Furthermore, particularly following attention shifts, TBS suppressed the neural signal in bilateral FEF, right inferior and superior parietal lobule (IPL/SPL) and bilateral supramarginal gyri (SMG). Terbium 54-57 sphingosine-1-phosphate lyase 1 Homo sapiens 154-157 28302070-18 2017 Family history of TB contact has substantaially increased the risk of developing the disease, and there is a need to improve ways of identifying TB cases and intensify mechanisms of tracing contacts among household members of PTB+ cases. Terbium 18-20 polypyrimidine tract binding protein 1 Homo sapiens 226-229 26671506-4 2017 In this work, the biological interaction between terbium-doped gadolinium oxysulfide nanoparticles (GOSNPs) with human peripheral blood mononuclear cells (PBMC), human-derived macrophages (THP-1), and human cervical carcinoma cell (HeLa) were evaluated. Terbium 49-56 GLI family zinc finger 2 Homo sapiens 189-194 28013361-4 2017 Compared to WT mice, Dmp1-hWNT16 TG mice exhibited significantly higher whole-body, spine and femoral aBMD, BMC and trabecular (BV/TV, Tb.N, and Tb.Th) and cortical (bone area and thickness) parameters in both male and female at 12 weeks of age. Terbium 135-137 dentin matrix protein 1 Mus musculus 21-25 27900437-11 2017 When comparing responses to TBS according to BDNF polymorphism, in healthy subjects, Met carriers showed reduced MEP changes compared with Val/Val individuals. Terbium 28-31 brain derived neurotrophic factor Homo sapiens 45-49 29026395-8 2017 CONCLUSION: Tuberculosis incidence among HIV-infected adults with medium/high CD4 count in Bagamoyo is lower than in other high TB burden countries. Terbium 128-130 CD4 molecule Homo sapiens 78-81 27884746-5 2017 We will describe CDD"s efforts in assisting with the MM4TB project. Terbium 56-58 natriuretic peptide A Homo sapiens 17-20 28250925-10 2017 CONCLUSION: Collectively, these results indicate that these FasL-expressing B-cells are being induced during anti-TB treatment, and thus may play a positive role. Terbium 114-116 Fas ligand Homo sapiens 60-64 28133458-8 2016 The mechanistic studies demonstrated that two of three co-infected animals had lower levels of M.tb specific IFN-gamma and IL-22 in PBMCs than M.tb mono-infected animals. Terbium 97-99 interferon gamma Homo sapiens 109-118 27682872-10 2017 Our results show that increased activation of B-cells is present following successful TB treatment, and that the expression of FASLG and IL5RA could potentially be utilised as a signature to monitor treatment response. Terbium 86-88 Fas ligand Homo sapiens 127-132 27682872-10 2017 Our results show that increased activation of B-cells is present following successful TB treatment, and that the expression of FASLG and IL5RA could potentially be utilised as a signature to monitor treatment response. Terbium 86-88 interleukin 5 receptor subunit alpha Homo sapiens 137-142 29159180-8 2017 In the MRI group, the accuracy of TB was higher than SB (94.7% versus 84.2%, p = 0.001) for the patients with PSA >= 10 ng/mL. Terbium 34-36 kallikrein related peptidase 3 Homo sapiens 110-113 29159180-10 2017 The accuracy of TB was better than SB in the patients with serum PSA >= 10 ng/mL. Terbium 16-18 kallikrein related peptidase 3 Homo sapiens 65-68 27743106-7 2017 The Delhi/CAS and Beijing sub-lineage isolates were prevalent among patients who had been previously treated for TB. Terbium 113-115 BCAR1 scaffold protein, Cas family member Homo sapiens 10-13 28061954-11 2017 Cytokines such as IL-2 and IL-10 may serve as biomarkers for distinguishing ATB from LTBI and healthy control and may contribute to intervention and improvement in TB diagnosis. Terbium 77-79 interleukin 2 Homo sapiens 18-22 28107952-3 2017 The probe possesses high luminescence due to the sensitization of Ag+; While in alkaline solutions, Ag+ in Tb/GMP/Ag immediately binds to OH-, forming Ag2O precipitation and resulting in a distinct fluorescence quenching of Tb/GMP/Ag. Terbium 107-109 anterior gradient 2, protein disulphide isomerase family member Homo sapiens 151-154 28107952-3 2017 The probe possesses high luminescence due to the sensitization of Ag+; While in alkaline solutions, Ag+ in Tb/GMP/Ag immediately binds to OH-, forming Ag2O precipitation and resulting in a distinct fluorescence quenching of Tb/GMP/Ag. Terbium 224-226 anterior gradient 2, protein disulphide isomerase family member Homo sapiens 151-154 28197610-0 2017 Novel and easy access to highly luminescent Eu and Tb doped ultra-small CaF2, SrF2 and BaF2 nanoparticles - structure and luminescence. Terbium 51-53 CCR4-NOT transcription complex subunit 8 Homo sapiens 72-76 28197610-0 2017 Novel and easy access to highly luminescent Eu and Tb doped ultra-small CaF2, SrF2 and BaF2 nanoparticles - structure and luminescence. Terbium 51-53 BANF family member 2 Homo sapiens 87-91 28173836-2 2017 Neutrophils are the key mediators of TB immunopathology, and raised CSF matrix metalloproteinase-9 (MMP-9) which correlates to neutrophil count in CNS-TB is associated with neurological deficit and death. Terbium 151-153 matrix metallopeptidase 9 Homo sapiens 100-105 27682872-0 2017 Successful TB treatment induces B-cells expressing FASL and IL5RA mRNA. Terbium 11-13 Fas ligand Homo sapiens 51-55 27682872-0 2017 Successful TB treatment induces B-cells expressing FASL and IL5RA mRNA. Terbium 11-13 interleukin 5 receptor subunit alpha Homo sapiens 60-65 27682872-4 2017 We evaluated B-cell mRNA expression using real-time PCR from healthy community controls, individuals with other lung diseases and newly diagnosed untreated pulmonary TB patients at three different time points (diagnosis, month 2 and 6 of treatment).We show that FASLG, IL5RA, CD38 and IL4 expression was lower in B-cells from TB cases compared to healthy controls. Terbium 166-168 Fas ligand Homo sapiens 262-267 27682872-5 2017 The changes in expression levels of CD38 may be due to a reduced activation of B-cells from TB cases at diagnosis. Terbium 92-94 CD38 molecule Homo sapiens 36-40 27682872-6 2017 By month 2 of treatment, there was a significant increase in the expression of APRIL and IL5RA in TB cases. Terbium 98-100 interleukin 5 receptor subunit alpha Homo sapiens 89-94 27682872-7 2017 Furthermore, after 6 months of treatment, APRIL, FASLG, IL5RA and CD19 were upregulated in B-cells from TB cases. Terbium 104-106 Fas ligand Homo sapiens 49-54 27682872-7 2017 Furthermore, after 6 months of treatment, APRIL, FASLG, IL5RA and CD19 were upregulated in B-cells from TB cases. Terbium 104-106 interleukin 5 receptor subunit alpha Homo sapiens 56-61 27682872-7 2017 Furthermore, after 6 months of treatment, APRIL, FASLG, IL5RA and CD19 were upregulated in B-cells from TB cases. Terbium 104-106 CD19 molecule Homo sapiens 66-70 27682872-8 2017 The increase in the expression of APRIL and CD19 suggests that there may be restored activation of B-cells following anti-TB treatment. Terbium 122-124 CD19 molecule Homo sapiens 44-48 28060926-9 2017 However, keeping in view the cost, and other logistics, TST remains the most preferred method for LTBI diagnosis in resource-limited, high TB-burden settings. Terbium 99-101 thiosulfate sulfurtransferase Homo sapiens 56-59 29120574-8 2017 There is a strong association between PTX3 plasma level and the activity and severity of pulmonary TB. Terbium 99-101 pentraxin 3 Homo sapiens 38-42 28336310-8 2017 The study also suggests GG genotype of CXCL10 -135G/A (rs56061981) polymorphism decreased CXCL10 expression in T cells which may have defective recruitment of mononuclear cells at the site of infection as well granuloma formation and in turn contribute to progression of TB. Terbium 271-273 C-X-C motif chemokine ligand 10 Homo sapiens 39-45 28336310-8 2017 The study also suggests GG genotype of CXCL10 -135G/A (rs56061981) polymorphism decreased CXCL10 expression in T cells which may have defective recruitment of mononuclear cells at the site of infection as well granuloma formation and in turn contribute to progression of TB. Terbium 271-273 C-X-C motif chemokine ligand 10 Homo sapiens 90-96 28359736-2 2017 Gene polymorphisms that modulate HLA Class I and II antigens are among the risk markers for TB, along with other biologic, and social determinants of health. Terbium 92-94 major histocompatibility complex, class II, DQ beta 1 Homo sapiens 33-36 28359736-10 2017 In this exploratory analysis of TB and HLA allele frequencies in Dene and Cree cohorts HLA-A*03 and HLA-DQB1*05:03 were significantly associated with TB. Terbium 32-34 major histocompatibility complex, class I, A Homo sapiens 87-92 28359736-10 2017 In this exploratory analysis of TB and HLA allele frequencies in Dene and Cree cohorts HLA-A*03 and HLA-DQB1*05:03 were significantly associated with TB. Terbium 32-34 major histocompatibility complex, class II, DQ beta 1 Homo sapiens 100-108 28359736-10 2017 In this exploratory analysis of TB and HLA allele frequencies in Dene and Cree cohorts HLA-A*03 and HLA-DQB1*05:03 were significantly associated with TB. Terbium 150-152 major histocompatibility complex, class II, DQ beta 1 Homo sapiens 39-42 28359736-10 2017 In this exploratory analysis of TB and HLA allele frequencies in Dene and Cree cohorts HLA-A*03 and HLA-DQB1*05:03 were significantly associated with TB. Terbium 150-152 major histocompatibility complex, class I, A Homo sapiens 87-92 28359736-10 2017 In this exploratory analysis of TB and HLA allele frequencies in Dene and Cree cohorts HLA-A*03 and HLA-DQB1*05:03 were significantly associated with TB. Terbium 150-152 major histocompatibility complex, class II, DQ beta 1 Homo sapiens 100-108 27717783-4 2017 RESULTS: Circulating levels of VEGF-A, C, D, R1, R2 and R3 were significantly higher in TB-DM compared to TB individuals. Terbium 88-90 vascular endothelial growth factor A Homo sapiens 31-58 27717783-7 2017 In addition, VEGF-A, C and R2 levels were significantly higher (at 2 months of treatment) in culture positive compared to culture negative TB-DM individuals. Terbium 139-141 vascular endothelial growth factor A Homo sapiens 13-19 27833051-13 2017 The brain levels of p-VASP, p-CREB, and BDNF were higher in the TB mice compared with those in the CN mice. Terbium 64-66 vasodilator-stimulated phosphoprotein Mus musculus 22-26 27833051-13 2017 The brain levels of p-VASP, p-CREB, and BDNF were higher in the TB mice compared with those in the CN mice. Terbium 64-66 cAMP responsive element binding protein 1 Mus musculus 30-34 27833051-13 2017 The brain levels of p-VASP, p-CREB, and BDNF were higher in the TB mice compared with those in the CN mice. Terbium 64-66 brain derived neurotrophic factor Mus musculus 40-44 27901526-3 2016 The functionality of the conjugates was demonstrated by terbium (Tb)-to-QD FRET immunoassays against prostate specific antigen in serum samples. Terbium 56-63 kallikrein related peptidase 3 Homo sapiens 101-126 27901526-3 2016 The functionality of the conjugates was demonstrated by terbium (Tb)-to-QD FRET immunoassays against prostate specific antigen in serum samples. Terbium 65-67 kallikrein related peptidase 3 Homo sapiens 101-126 28000588-7 2016 CONCLUSION: ICL could be used in combination with other M. tuberculosis antigens to improve the sensitivity and specificity of current serological TB diagnostic methods. Terbium 147-149 isocitrate lyase Mycobacterium tuberculosis H37Rv 12-15 28197382-7 2017 The S100A8+-associated tumor budding (SATB) index determined by the S100A8+TIF and TB was an independent predictor of overall survival (p = 0.001) other than the S100A8+TIF or TB alone. Terbium 40-42 S100 calcium binding protein A8 Homo sapiens 4-10 28197382-7 2017 The S100A8+-associated tumor budding (SATB) index determined by the S100A8+TIF and TB was an independent predictor of overall survival (p = 0.001) other than the S100A8+TIF or TB alone. Terbium 40-42 S100 calcium binding protein A8 Homo sapiens 68-74 28197382-7 2017 The S100A8+-associated tumor budding (SATB) index determined by the S100A8+TIF and TB was an independent predictor of overall survival (p = 0.001) other than the S100A8+TIF or TB alone. Terbium 40-42 TYRO3 protein tyrosine kinase Homo sapiens 75-78 28197382-7 2017 The S100A8+-associated tumor budding (SATB) index determined by the S100A8+TIF and TB was an independent predictor of overall survival (p = 0.001) other than the S100A8+TIF or TB alone. Terbium 40-42 S100 calcium binding protein A8 Homo sapiens 68-74 27108447-12 2016 PET images of mice, which received (152)Tb-DOTANOC at small peptide amounts, revealed the best tumor-to-kidney ratios. Terbium 40-42 thyroid stimulating hormone receptor Mus musculus 0-3 27108447-13 2016 The data obtained with (177)Lu-DOTANOC in biodistribution and SPECT/CT imaging studies confirmed the (152)Tb-based PET results. Terbium 106-108 thyroid stimulating hormone receptor Mus musculus 115-118 27650481-10 2016 L-type voltage-dependent calcium channels (L-VDCC) and the metabotropic glutamate receptor-5 (mGluR5) equally contributed in DH and VH to compound LTP induced by relatively long TBS. Terbium 178-181 glutamate metabotropic receptor 5 Rattus norvegicus 59-92 27650481-10 2016 L-type voltage-dependent calcium channels (L-VDCC) and the metabotropic glutamate receptor-5 (mGluR5) equally contributed in DH and VH to compound LTP induced by relatively long TBS. Terbium 178-181 glutamate receptor, ionotropic, kainate 1 Mus musculus 94-100 28043521-13 2016 CONCLUSION: Compared to the healthy control group, patients with TB had significantly lower levels of IL-10. Terbium 65-67 interleukin 10 Homo sapiens 102-107 28043521-16 2016 Standard 2-month TB therapy results in reversal of inflammation characterized by increased IL-10 to a level comparable to that in healthy donors. Terbium 17-19 interleukin 10 Homo sapiens 91-96 28043521-17 2016 IL-10 is an immune correlate of treatment outcome and can help to identify a better strategy for TB management. Terbium 97-99 interleukin 10 Homo sapiens 0-5 28043583-3 2016 The present study aimed to investigate the TB radiographic manifestation in HIV+ patients and its relationship to the CD4 cell count. Terbium 43-45 CD4 molecule Homo sapiens 118-121 28043583-12 2016 At this level of immunity, CD4+ T cell dysfunction may play a deterministic role in TB radiographic manifestation. Terbium 84-86 CD4 molecule Homo sapiens 27-30 27752975-4 2016 The epitaxial growth of inert CaF2 and silica shell, respectively, on their surface forming as CaF2:Ce/Tb@CaF2 (core/shell) and CaF2:Ce/Tb@CaF2@SiO2 (core/shell/SiO2) nanoarchitecture. Terbium 103-105 CCR4-NOT transcription complex subunit 8 Homo sapiens 30-34 27357175-12 2016 Total hip and TB measurements were positively associated with cIMT, with similar magnitudes of association to those found in their mothers. Terbium 14-16 CIMT Homo sapiens 62-66 27752975-12 2016 A newly designed CaF2:Ce/Tb nanoparticles via metal complex decomposition rout shows high dispersibility in aqueous solvents with enhanced photoluminescence. Terbium 25-27 CCR4-NOT transcription complex subunit 8 Homo sapiens 17-21 27245780-10 2016 Hypoxia increased MMP-1 expression in primary respiratory epithelial cells via intercellular networks regulated by TB. Terbium 115-117 matrix metallopeptidase 1 Homo sapiens 18-23 26829564-1 2016 Choroidal neovascularization secondary to tuberculous serpiginous-like choroiditis (Tb-SLC) is uncommon and requires further invasive imaging, such as fluorescein and indocyanine green angiography. Terbium 84-86 C-C motif chemokine ligand 21 Homo sapiens 87-90 26829564-2 2016 We evaluate the optical coherence tomography angiography (OCTA) findings in a patient with a Tb-SLC and present the use of this investigation as a non-invasive diagnostic and follow-up clinical tool in this disease. Terbium 93-95 C-C motif chemokine ligand 21 Homo sapiens 96-99 27865385-7 2016 Finally, clinical improvement following effective anti-TB therapy is correlated with significantly decreased expression of PD-1 in Tresp and Teff cells, but not in Treg cells. Terbium 55-57 MHC class I antigen 1 Sus scrofa 123-127 27941164-0 2016 Single nucleotide polymorphisms of IFNgamma (+874 A/T) and IFNgammaR1 (-56 C/T) in Iranian patients with TB. Terbium 105-107 interferon gamma Homo sapiens 35-43 27941164-0 2016 Single nucleotide polymorphisms of IFNgamma (+874 A/T) and IFNgammaR1 (-56 C/T) in Iranian patients with TB. Terbium 105-107 interferon gamma receptor 1 Homo sapiens 59-69 27941164-3 2016 METHODS: We investigated the single nucleotide polymorphisms (SNPs) in genes of IFNgamma (+874 A/T) and IFNgammaR1 (-56 C/T) and serum level of IFNgamma and their influence on TB in patients; 300 patients with TB and 300 healthy controls were enrolled in this study. Terbium 176-178 interferon gamma Homo sapiens 80-88 27941164-3 2016 METHODS: We investigated the single nucleotide polymorphisms (SNPs) in genes of IFNgamma (+874 A/T) and IFNgammaR1 (-56 C/T) and serum level of IFNgamma and their influence on TB in patients; 300 patients with TB and 300 healthy controls were enrolled in this study. Terbium 176-178 interferon gamma Homo sapiens 104-112 27941164-3 2016 METHODS: We investigated the single nucleotide polymorphisms (SNPs) in genes of IFNgamma (+874 A/T) and IFNgammaR1 (-56 C/T) and serum level of IFNgamma and their influence on TB in patients; 300 patients with TB and 300 healthy controls were enrolled in this study. Terbium 210-212 interferon gamma Homo sapiens 80-88 27941164-3 2016 METHODS: We investigated the single nucleotide polymorphisms (SNPs) in genes of IFNgamma (+874 A/T) and IFNgammaR1 (-56 C/T) and serum level of IFNgamma and their influence on TB in patients; 300 patients with TB and 300 healthy controls were enrolled in this study. Terbium 210-212 interferon gamma Homo sapiens 104-112 27941164-6 2016 Allele T frequencies of IFNgammaR1 -56 C/T promoter region in patients with pulmonary TB (PTB) or extrapulmonary TB (EPTB) were significantly greater than allele C. The -56 TT motif of IFNgammaR1 is associated with both forms of TB (p<0.05). Terbium 86-88 interferon gamma receptor 1 Homo sapiens 24-34 27941164-6 2016 Allele T frequencies of IFNgammaR1 -56 C/T promoter region in patients with pulmonary TB (PTB) or extrapulmonary TB (EPTB) were significantly greater than allele C. The -56 TT motif of IFNgammaR1 is associated with both forms of TB (p<0.05). Terbium 86-88 interferon gamma receptor 1 Homo sapiens 185-195 27941164-6 2016 Allele T frequencies of IFNgammaR1 -56 C/T promoter region in patients with pulmonary TB (PTB) or extrapulmonary TB (EPTB) were significantly greater than allele C. The -56 TT motif of IFNgammaR1 is associated with both forms of TB (p<0.05). Terbium 91-93 interferon gamma receptor 1 Homo sapiens 24-34 27941164-6 2016 Allele T frequencies of IFNgammaR1 -56 C/T promoter region in patients with pulmonary TB (PTB) or extrapulmonary TB (EPTB) were significantly greater than allele C. The -56 TT motif of IFNgammaR1 is associated with both forms of TB (p<0.05). Terbium 91-93 interferon gamma receptor 1 Homo sapiens 24-34 27941164-7 2016 The serum level of IFNgamma was significantly higher in patients with TB than in controls, but there was no significant difference between serum level of IFNgamma and the studied genotypes (p>0.05). Terbium 70-72 interferon gamma Homo sapiens 19-27 27941164-8 2016 CONCLUSIONS: The cause of active TB in the patients seems to be due to the lack of effective IFNgamma function or the lack of effective signaling connection between IFNgamma and its receptor in presence of -56 C/T polymorphism in promoter region of IFNgammaR1 gene. Terbium 33-35 interferon gamma Homo sapiens 93-101 27941164-8 2016 CONCLUSIONS: The cause of active TB in the patients seems to be due to the lack of effective IFNgamma function or the lack of effective signaling connection between IFNgamma and its receptor in presence of -56 C/T polymorphism in promoter region of IFNgammaR1 gene. Terbium 33-35 interferon gamma receptor 1 Homo sapiens 249-259 27865390-7 2016 Vaccine-induced multifunctional CD4 T-cells producing IFN-gamma and TNF-alpha were associated with reduced disease pathology following subsequent M.tb challenge; however, high frequencies of this population following M.tb infection correlated with increased pathology. Terbium 148-150 CD4 molecule Homo sapiens 32-35 27865390-7 2016 Vaccine-induced multifunctional CD4 T-cells producing IFN-gamma and TNF-alpha were associated with reduced disease pathology following subsequent M.tb challenge; however, high frequencies of this population following M.tb infection correlated with increased pathology. Terbium 148-150 interferon gamma Homo sapiens 54-63 27876780-2 2016 Earlier studies revealed that MBL2 gene variants, rs1800451, rs1800450, rs5030737, rs7096206, rs11003125 and rs7095891 are associated with impaired serum level and susceptibility to TB, but their results are inconsistent. Terbium 182-184 mannose binding lectin 2 Homo sapiens 30-34 28078191-4 2016 The results showed a strong correlation between two polymorphisms in different loci of TNF-alpha gene including TNF-alpha T-857 C and A 238 G. But no association were found in TNFR2 genes with susceptibility to TB. Terbium 211-213 tumor necrosis factor Homo sapiens 87-96 27876780-8 2016 In conclusion, MBL2 rs1800450 and rs1800451 polymorphisms play a protective role in TB infection and reinforce their critical significance as a potential genetic marker for TB resistance. Terbium 84-86 mannose binding lectin 2 Homo sapiens 15-19 27813605-6 2016 Higher frequencies of TNF-alpha-308 GA genotype and TNF-alpha-308 allele (A) in OA-TB patients (20.8 and 10.4%, respectively) than in healthy volunteers (8.0 and 5.0%, respectively) indicated an association with increased risk of OA-TB (OR = 3.112, 95%CI = 1.520-6.343, P = 0.003; OR = 3.109, 95%CI = 1.676-6.538, P = 0.006; respectively). Terbium 83-85 tumor necrosis factor Homo sapiens 22-31 27755875-3 2016 Upon varying the isomeric structure of C82 cage from C2(5) to Cs(6) and to C2v(9), the entrapped triangular TbNC cluster exhibits significant distortions as evidenced by the changes of Tb-C(N) and C-N bond distances and variation of the Tb-C(N)-N(C) angle by up to 20 , revealing that the geometric structure of the entrapped triangular TbNC cluster is variable. Terbium 108-110 complement C8 beta chain Homo sapiens 39-42 27755875-3 2016 Upon varying the isomeric structure of C82 cage from C2(5) to Cs(6) and to C2v(9), the entrapped triangular TbNC cluster exhibits significant distortions as evidenced by the changes of Tb-C(N) and C-N bond distances and variation of the Tb-C(N)-N(C) angle by up to 20 , revealing that the geometric structure of the entrapped triangular TbNC cluster is variable. Terbium 185-187 complement C8 beta chain Homo sapiens 39-42 27328397-3 2016 In the present study, the TBs that were deposited during May 2013 and May 2014 on the Goa coast were backtracked through a trajectory model, primarily to simulate their pathways and identify the reason for the occurrence of TBs only in May, and eventually to identify the origin and the source. Terbium 26-29 tripartite motif containing 47 Homo sapiens 86-89 28061948-7 2017 Of the four miRNAs studied, the levels of miR-16 were significantly elevated and miR-155 were significantly reduced in serum of TB patients as compared to uninfected controls. Terbium 128-130 glycerophosphodiester phosphodiesterase 1 Homo sapiens 42-48 28061948-7 2017 Of the four miRNAs studied, the levels of miR-16 were significantly elevated and miR-155 were significantly reduced in serum of TB patients as compared to uninfected controls. Terbium 128-130 microRNA 155 Homo sapiens 81-88 28061948-10 2017 In patients with MDR TB, miR-155 was lower as compared to healthy controls and TB treated group but higher as compared to TB naive patients. Terbium 21-23 microRNA 155 Homo sapiens 25-32 28061948-10 2017 In patients with MDR TB, miR-155 was lower as compared to healthy controls and TB treated group but higher as compared to TB naive patients. Terbium 79-81 microRNA 155 Homo sapiens 25-32 28061948-10 2017 In patients with MDR TB, miR-155 was lower as compared to healthy controls and TB treated group but higher as compared to TB naive patients. Terbium 79-81 microRNA 155 Homo sapiens 25-32 28061948-11 2017 miR-16 levels were lowest in serum of MDR TB patients compared to TB naive, TB treated group and healthy controls. Terbium 42-44 glycerophosphodiester phosphodiesterase 1 Homo sapiens 0-6 28061948-11 2017 miR-16 levels were lowest in serum of MDR TB patients compared to TB naive, TB treated group and healthy controls. Terbium 66-68 glycerophosphodiester phosphodiesterase 1 Homo sapiens 0-6 27813605-7 2016 Haplotype association analysis of TNF-alpha polymorphisms (-308/-238/-863) showed a higher frequency of TNF-alpha AGA in OA-TB patients (12.1%) than in healthy volunteers (3.5%), indicating that it was a risk factor for OA-TB (OR = 4.201, 95%CI = 1.80-9.91, P = 0.010). Terbium 124-126 tumor necrosis factor Homo sapiens 34-43 27813605-7 2016 Haplotype association analysis of TNF-alpha polymorphisms (-308/-238/-863) showed a higher frequency of TNF-alpha AGA in OA-TB patients (12.1%) than in healthy volunteers (3.5%), indicating that it was a risk factor for OA-TB (OR = 4.201, 95%CI = 1.80-9.91, P = 0.010). Terbium 124-126 tumor necrosis factor Homo sapiens 104-113 27495897-4 2016 However, it has been observed that the administration of 3-thienylboronic acid (3TB) induced motor disruption in CD1 mice. Terbium 81-83 CD1 antigen complex Mus musculus 113-116 27410668-1 2016 We report here the determination of the helical spin structure of three Ln-based chiral chains of the formula [Ln(Hnic)(nic)2(NO3)]n (Hnic = nicotinic acid; Ln = Tb, Dy, and Er) by means of cantilever torque magnetometry. Terbium 162-164 spindlin 1 Homo sapiens 48-52 27751168-4 2016 In this study we seek to evaluate the effectiveness of cART in reducing mortality among TB-HIV co-infected patients with CD4 + T cells above 350cells/mm3 at the time of TB diagnosis. Terbium 88-90 CD4 molecule Homo sapiens 121-124 27523388-6 2016 The antigen-specific release of each cytokine, IFN-gamma, IP-10, and MCP-1, was significantly higher in the TB groups than in either the non-tuberculous pulmonary disease group (p < 0.001) or the healthy control group (p < 0.001). Terbium 108-110 interferon gamma Homo sapiens 47-56 27523388-6 2016 The antigen-specific release of each cytokine, IFN-gamma, IP-10, and MCP-1, was significantly higher in the TB groups than in either the non-tuberculous pulmonary disease group (p < 0.001) or the healthy control group (p < 0.001). Terbium 108-110 C-X-C motif chemokine ligand 10 Homo sapiens 58-63 27523388-6 2016 The antigen-specific release of each cytokine, IFN-gamma, IP-10, and MCP-1, was significantly higher in the TB groups than in either the non-tuberculous pulmonary disease group (p < 0.001) or the healthy control group (p < 0.001). Terbium 108-110 C-C motif chemokine ligand 2 Homo sapiens 69-74 27443659-9 2016 After the first DRESS syndrome diagnosis, anti-TB medications were changed to isoniazid, ethambutol, pyrazinamide, cycloserine, and streptomycin, which also caused a skin rash, itching, and elevated AST/ALT levels, and eosinophil count. Terbium 47-49 solute carrier family 17 member 5 Homo sapiens 199-202 27523048-8 2016 Plasma parameters of lactate dehydrogenase (LDH), creatine kinase (CK) and tumor necrosis factor-alpha (TNF-alpha) were higher in the TB group, suggesting predominance of catabolic and pro-inflammatory activities. Terbium 134-136 tumor necrosis factor Mus musculus 104-113 27782732-2 2016 The authors hypothesize that a gadolinium oxysulfide: terbium (GOS:Tb) flexible scintillator, which loosely conforms to the body contour, can enhance tumor signal-to-background ratio (SBR) compared with RLI, which utilizes a flat scintillator. Terbium 54-61 ATP-binding cassette, sub-family E (OABP), member 1 Mus musculus 203-206 27495897-5 2016 In the current contribution we studied in deeper form the disruption of motor performance produced by the intraperitoneal administration of 3TB in mice from two strains (CD1 and C57BL6). Terbium 141-143 CD1 antigen complex Mus musculus 170-173 27630328-2 2016 The aim of the study was to study whether TB correlates with aggressiveness in cutaneous SCC. Terbium 42-44 serpin family B member 3 Homo sapiens 89-92 27630328-4 2016 TB was expressed as the mean number of tumour buds in five adjacent high-power fields of each SCC. Terbium 0-2 serpin family B member 3 Homo sapiens 94-97 27630328-5 2016 RESULTS: Aggressive SCC had a much higher TB score compared to control SCC (1.63+-1.35 vs. 0.49+-0.9, p<0.001). Terbium 42-44 serpin family B member 3 Homo sapiens 20-23 27630328-7 2016 Further studies including a larger number of tumours will hopefully validate TB as a new pathological predictor of aggressiveness in cutaneous SCC and will allow its correlation with other pathological features of SCC aggressiveness to be defined. Terbium 77-79 serpin family B member 3 Homo sapiens 143-146 26776460-7 2016 Strikingly in the TB-PE cases, comparison of disease site, i.e. pleural effusion with peripheral blood showed increased expression of both soluble and surface HLA-G, whereas ILT-2 expressing cells were reduced at the local disease site. Terbium 18-20 major histocompatibility complex, class I, G Homo sapiens 159-164 27320207-13 2016 Likewise, Hdac4(-/-) mice exhibit significantly increased Tb.Th and bone mineral density (BMD) while the Hdac4(-/-)/Mmp13(-/-) mice significantly recovered these parameters toward normal for this age. Terbium 58-60 histone deacetylase 4 Mus musculus 10-15 26776460-7 2016 Strikingly in the TB-PE cases, comparison of disease site, i.e. pleural effusion with peripheral blood showed increased expression of both soluble and surface HLA-G, whereas ILT-2 expressing cells were reduced at the local disease site. Terbium 18-20 leukocyte immunoglobulin like receptor B1 Homo sapiens 174-179 27289452-5 2016 In this study, based on the observation that TcpB binds to the host target proteins, MAL, through the TIR domain, we examined decoy peptides from TcpB TIR domains and found that TB-8 and TB-9 substantially inhibit lipopolysaccharide (LPS)-induced signaling in vitro and in vivo. Terbium 178-180 mal, T cell differentiation protein Homo sapiens 85-88 27289452-5 2016 In this study, based on the observation that TcpB binds to the host target proteins, MAL, through the TIR domain, we examined decoy peptides from TcpB TIR domains and found that TB-8 and TB-9 substantially inhibit lipopolysaccharide (LPS)-induced signaling in vitro and in vivo. Terbium 187-189 mal, T cell differentiation protein Homo sapiens 85-88 27291706-6 2016 On addition of H2S, the -N3 group can be reduced to an amine group to break the process of ICT, and the luminescence of Tb(3+) is recovered at a nanomolar sensitivity level. Terbium 120-122 histocompatibility 2, S region (C4, Slp, Bf, C2) Mus musculus 15-18 27072810-8 2016 In addition, a significant level of epitope-specific T cells could be detected ex vivo in peripheral blood mononuclear cells from active TB patients by an HLA-A*11:01 dextramer carrying the peptide Rv3130c194-204 (from the MTB triacylglycerol synthase Tgs1), which was the most frequently recognized epitope in our peptide library. Terbium 137-139 major histocompatibility complex, class I, A Homo sapiens 155-160 27072810-9 2016 In conclusion, this study identified six dominant CD8(+) T cell epitopes that may be considered potential targets for subunit vaccines or diagnostic strategies against TB. Terbium 168-170 CD8a molecule Homo sapiens 50-53 26180934-6 2016 In contrast, BCC exhibited an increased expression of E-cadherin in relation to TE and TB (P=0.009). Terbium 87-89 cadherin 1 Homo sapiens 54-64 27746865-12 2016 The frequency of IL-17 producing CD4+ T cells in patients with active TB was lower than LTB subjects (P<0.05). Terbium 70-72 interleukin 17A Homo sapiens 17-22 27746865-13 2016 CONCLUSION: The results of the present study might suggest that IL-17 and IL-23 play critical roles in the immune response against TB. Terbium 131-133 interleukin 17A Homo sapiens 64-69 27746865-13 2016 CONCLUSION: The results of the present study might suggest that IL-17 and IL-23 play critical roles in the immune response against TB. Terbium 131-133 interleukin 23 subunit alpha Homo sapiens 74-79 26959510-9 2016 With attainment of a CD4 cell count level 200-350 cells/mul, there was a substantial reduction in events/100 PYAR - by 91% to 1.45 (1.29-1.63) for TB, by 94% to 0.75 (0.64-0.89) for oral candidiasis, by 84% to 0.99 (0.86-1.14) for Herpes Zoster, and by 78% to 1.22 (1.07-1.39) for chronic diarrhea. Terbium 147-149 CD4 molecule Homo sapiens 21-24 27347810-3 2016 Herein, by optimizing the doping ratio of sensitizer and activator to maximize the utilization of the photon energy and introducing the CaF2 inert shell to shield sensitizer from quenchers, we synthesize ultrasmall NaYbF4:Tb@CaF2 nanoparticles with a significant enhancement (690-fold) in cooperative sensitization upconversion emission intensity, compared with the parent NaYbF4:Tb. Terbium 222-224 CCR4-NOT transcription complex subunit 8 Homo sapiens 136-140 27347810-3 2016 Herein, by optimizing the doping ratio of sensitizer and activator to maximize the utilization of the photon energy and introducing the CaF2 inert shell to shield sensitizer from quenchers, we synthesize ultrasmall NaYbF4:Tb@CaF2 nanoparticles with a significant enhancement (690-fold) in cooperative sensitization upconversion emission intensity, compared with the parent NaYbF4:Tb. Terbium 222-224 CCR4-NOT transcription complex subunit 8 Homo sapiens 225-229 27347810-3 2016 Herein, by optimizing the doping ratio of sensitizer and activator to maximize the utilization of the photon energy and introducing the CaF2 inert shell to shield sensitizer from quenchers, we synthesize ultrasmall NaYbF4:Tb@CaF2 nanoparticles with a significant enhancement (690-fold) in cooperative sensitization upconversion emission intensity, compared with the parent NaYbF4:Tb. Terbium 380-382 CCR4-NOT transcription complex subunit 8 Homo sapiens 136-140 27347810-3 2016 Herein, by optimizing the doping ratio of sensitizer and activator to maximize the utilization of the photon energy and introducing the CaF2 inert shell to shield sensitizer from quenchers, we synthesize ultrasmall NaYbF4:Tb@CaF2 nanoparticles with a significant enhancement (690-fold) in cooperative sensitization upconversion emission intensity, compared with the parent NaYbF4:Tb. Terbium 380-382 CCR4-NOT transcription complex subunit 8 Homo sapiens 225-229 27347810-4 2016 The lifetime of Tb(3+) emission in NaYbF4:Tb@CaF2 nanoparticles is prolonged extensively to ~3.5 ms. Terbium 16-18 CCR4-NOT transcription complex subunit 8 Homo sapiens 45-49 27347810-5 2016 Furthermore, NaYbF4:Tb@CaF2 was applied in in vitro and in vivo bioimaging. Terbium 20-22 CCR4-NOT transcription complex subunit 8 Homo sapiens 23-27 26180934-8 2016 Combining consecutive staining of E-cadherin and CK20 could even enhance specificity toward diagnosis of TE or TB. Terbium 111-113 cadherin 1 Homo sapiens 34-44 26180934-8 2016 Combining consecutive staining of E-cadherin and CK20 could even enhance specificity toward diagnosis of TE or TB. Terbium 111-113 keratin 20 Homo sapiens 49-53 27002606-5 2016 RESULTS: IFN-gamma and IL-12 cytokine production markedly decreased and that of IL-10 increased after Ag85A M.tb stimulation, however anti TB treatment reconstituted the response in TBDM and PTB patients. Terbium 110-112 interferon gamma Homo sapiens 9-18 27129162-8 2016 Importantly, chemical inhibition of xCT with sulfasalazine, a specific xCT inhibitor that is already approved by the FDA for treatment of inflammatory bowel disease, produces similar protective effects in vivo and in vitro, indicating xCT might be a novel and useful target for host-directed TB treatment strategy. Terbium 292-294 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 Mus musculus 36-39 27408780-6 2016 Inhibition of Mc3r transcription by a loxP-flanked transcriptional blocker (TB) in C57BL/6JN mice (Mc3r (TB/TB) ) was reversed in mesolimbic neurons using DAT-Cre (DAT-MC3R). Terbium 105-107 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus 164-167 27408780-6 2016 Inhibition of Mc3r transcription by a loxP-flanked transcriptional blocker (TB) in C57BL/6JN mice (Mc3r (TB/TB) ) was reversed in mesolimbic neurons using DAT-Cre (DAT-MC3R). Terbium 105-107 melanocortin 3 receptor Mus musculus 168-172 27030576-1 2016 BACKGROUND: The ability of interferon-gamma release assays to predict the development of TB has been investigated in many studies, but few cases develop TB during follow-up limiting the generalisation of results. Terbium 89-91 interferon gamma Homo sapiens 27-43 27450011-7 2016 RESULTS: In comparing the differences significant differences in TB Ag tube response of IL-17 and IP-10, and "TB Ag - Nil" response of IL-10 and IP-10 were evident between the active TB and non-active TB groups. Terbium 65-67 interleukin 17A Homo sapiens 88-93 27450011-7 2016 RESULTS: In comparing the differences significant differences in TB Ag tube response of IL-17 and IP-10, and "TB Ag - Nil" response of IL-10 and IP-10 were evident between the active TB and non-active TB groups. Terbium 65-67 C-X-C motif chemokine ligand 10 Homo sapiens 98-103 27450011-7 2016 RESULTS: In comparing the differences significant differences in TB Ag tube response of IL-17 and IP-10, and "TB Ag - Nil" response of IL-10 and IP-10 were evident between the active TB and non-active TB groups. Terbium 110-112 interleukin 10 Homo sapiens 135-140 27450011-7 2016 RESULTS: In comparing the differences significant differences in TB Ag tube response of IL-17 and IP-10, and "TB Ag - Nil" response of IL-10 and IP-10 were evident between the active TB and non-active TB groups. Terbium 110-112 interleukin 10 Homo sapiens 135-140 27450011-8 2016 From the calculation of diagnostic performance for differentiating active TB patients from QFT-positive patients, among the measured values, the value of IL-17 TB Ag tube with the cut-off value set to <=0.82 (AUC 0.742) showed sensitivity, specificity, positive predictive value, and negative predictive value of 69.2%, 97.5%, 96.4%, and 76.5%, respectively. Terbium 74-76 interleukin 17A Homo sapiens 154-159 27450011-9 2016 DISCUSSION: Among TB suspects, IL-17 TB Ag response had the highest ability to distinguish active TB followed by IP-10 TBAg-Nil response and the IL-17/IFN-gamma-TB Ag response combination improved the detection response. Terbium 18-20 interleukin 17A Homo sapiens 31-36 27450011-9 2016 DISCUSSION: Among TB suspects, IL-17 TB Ag response had the highest ability to distinguish active TB followed by IP-10 TBAg-Nil response and the IL-17/IFN-gamma-TB Ag response combination improved the detection response. Terbium 37-39 interleukin 17A Homo sapiens 31-36 27450011-9 2016 DISCUSSION: Among TB suspects, IL-17 TB Ag response had the highest ability to distinguish active TB followed by IP-10 TBAg-Nil response and the IL-17/IFN-gamma-TB Ag response combination improved the detection response. Terbium 37-39 interleukin 17A Homo sapiens 31-36 27450011-10 2016 Differentiating active TB is best done using IL-17 as a biomarker, with IP-10 and IL-10 being potential useful. Terbium 23-25 interleukin 17A Homo sapiens 45-50 27340556-3 2016 Previous reports in several populations have consistently demonstrated an association between polymorphisms in the N-acetyltransferase 2 (NAT2) gene, which is responsible for INH hepatic metabolism, and a risk of DILI in TB patients. Terbium 221-223 N-acetyltransferase 2 Homo sapiens 115-136 27340556-3 2016 Previous reports in several populations have consistently demonstrated an association between polymorphisms in the N-acetyltransferase 2 (NAT2) gene, which is responsible for INH hepatic metabolism, and a risk of DILI in TB patients. Terbium 221-223 N-acetyltransferase 2 Homo sapiens 138-142 27340556-8 2016 The findings demonstrated that slow NAT2 acetylator status is a significant predictor of the risk of DILI by anti-TB agents, and a personalized anti-TB treatment approach may aid in making treatment decisions and reducing the incidence of DILI. Terbium 114-116 N-acetyltransferase 2 Homo sapiens 36-40 26765255-13 2016 Pregnant women with IGRA(+)/TST(-) discordance had less IFN-gamma and IL-2 than those with concordant-positive results and may represent an especially high-risk subset for the development of active TB postpartum. Terbium 198-200 interferon gamma Homo sapiens 56-65 26765255-13 2016 Pregnant women with IGRA(+)/TST(-) discordance had less IFN-gamma and IL-2 than those with concordant-positive results and may represent an especially high-risk subset for the development of active TB postpartum. Terbium 198-200 interleukin 2 Homo sapiens 70-74 27286652-16 2016 CONCLUSION: The Six-month mortality of HIV critically ill patients with TB coinfection is high and strongly associated with the nadir CD4 cell count less than 50 cels/mm(3). Terbium 72-74 CD4 molecule Homo sapiens 134-137 27386579-4 2016 Immunostaining of different epitopes of the epidermal growth factor receptor (EGFR) with Tb- and QD-conjugated antibodies and nanobodies allowed for efficient Tb-to-QD FRET on A431 cell membranes. Terbium 89-91 epidermal growth factor receptor Homo sapiens 44-76 27386579-4 2016 Immunostaining of different epitopes of the epidermal growth factor receptor (EGFR) with Tb- and QD-conjugated antibodies and nanobodies allowed for efficient Tb-to-QD FRET on A431 cell membranes. Terbium 89-91 epidermal growth factor receptor Homo sapiens 78-82 27386579-4 2016 Immunostaining of different epitopes of the epidermal growth factor receptor (EGFR) with Tb- and QD-conjugated antibodies and nanobodies allowed for efficient Tb-to-QD FRET on A431 cell membranes. Terbium 159-161 epidermal growth factor receptor Homo sapiens 44-76 27386579-4 2016 Immunostaining of different epitopes of the epidermal growth factor receptor (EGFR) with Tb- and QD-conjugated antibodies and nanobodies allowed for efficient Tb-to-QD FRET on A431 cell membranes. Terbium 159-161 epidermal growth factor receptor Homo sapiens 78-82 27508089-3 2016 The objective of this study was to determine the prevalence of drug resistance to second-line TB drugs among MDR-TB cases detected in the Fourth National Anti-Tuberculosis Drug Resistance Survey in Viet Nam. Terbium 94-96 SH3 and cysteine rich domain 3 Homo sapiens 203-206 27076678-4 2016 HIV/TB patients exhibited higher proportions of monocytes expressing activated caspase-1 (casp1) pre-cART, compared with HIV patients without TB, and patients who developed TB-IRIS exhibited the greatest increase in casp1 expression. Terbium 4-6 caspase 1 Homo sapiens 79-88 27076678-4 2016 HIV/TB patients exhibited higher proportions of monocytes expressing activated caspase-1 (casp1) pre-cART, compared with HIV patients without TB, and patients who developed TB-IRIS exhibited the greatest increase in casp1 expression. Terbium 4-6 caspase 1 Homo sapiens 90-95 27076678-4 2016 HIV/TB patients exhibited higher proportions of monocytes expressing activated caspase-1 (casp1) pre-cART, compared with HIV patients without TB, and patients who developed TB-IRIS exhibited the greatest increase in casp1 expression. Terbium 4-6 caspase 1 Homo sapiens 216-221 27002606-5 2016 RESULTS: IFN-gamma and IL-12 cytokine production markedly decreased and that of IL-10 increased after Ag85A M.tb stimulation, however anti TB treatment reconstituted the response in TBDM and PTB patients. Terbium 110-112 interleukin 10 Homo sapiens 80-85 27284220-7 2016 SNP locus rs55617172 in TLR2 gene was found significantly (p<0.01) associated with susceptibility/resistance to TB in cattle. Terbium 115-117 toll like receptor 2 Bos taurus 24-28 26780979-13 2016 Plasma levels for CARTp were significantly elevated in TB but not PF mice whereas levels of TSH were unaffected. Terbium 55-57 CART prepropeptide Mus musculus 18-23 27408780-6 2016 Inhibition of Mc3r transcription by a loxP-flanked transcriptional blocker (TB) in C57BL/6JN mice (Mc3r (TB/TB) ) was reversed in mesolimbic neurons using DAT-Cre (DAT-MC3R). Terbium 76-78 melanocortin 3 receptor Mus musculus 14-18 27408780-6 2016 Inhibition of Mc3r transcription by a loxP-flanked transcriptional blocker (TB) in C57BL/6JN mice (Mc3r (TB/TB) ) was reversed in mesolimbic neurons using DAT-Cre (DAT-MC3R). Terbium 76-78 melanocortin 3 receptor Mus musculus 99-103 27408780-6 2016 Inhibition of Mc3r transcription by a loxP-flanked transcriptional blocker (TB) in C57BL/6JN mice (Mc3r (TB/TB) ) was reversed in mesolimbic neurons using DAT-Cre (DAT-MC3R). Terbium 76-78 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus 155-158 27408780-6 2016 Inhibition of Mc3r transcription by a loxP-flanked transcriptional blocker (TB) in C57BL/6JN mice (Mc3r (TB/TB) ) was reversed in mesolimbic neurons using DAT-Cre (DAT-MC3R). Terbium 76-78 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus 164-167 27408780-6 2016 Inhibition of Mc3r transcription by a loxP-flanked transcriptional blocker (TB) in C57BL/6JN mice (Mc3r (TB/TB) ) was reversed in mesolimbic neurons using DAT-Cre (DAT-MC3R). Terbium 76-78 melanocortin 3 receptor Mus musculus 168-172 27408780-6 2016 Inhibition of Mc3r transcription by a loxP-flanked transcriptional blocker (TB) in C57BL/6JN mice (Mc3r (TB/TB) ) was reversed in mesolimbic neurons using DAT-Cre (DAT-MC3R). Terbium 105-107 melanocortin 3 receptor Mus musculus 14-18 27408780-6 2016 Inhibition of Mc3r transcription by a loxP-flanked transcriptional blocker (TB) in C57BL/6JN mice (Mc3r (TB/TB) ) was reversed in mesolimbic neurons using DAT-Cre (DAT-MC3R). Terbium 105-107 melanocortin 3 receptor Mus musculus 99-103 27408780-6 2016 Inhibition of Mc3r transcription by a loxP-flanked transcriptional blocker (TB) in C57BL/6JN mice (Mc3r (TB/TB) ) was reversed in mesolimbic neurons using DAT-Cre (DAT-MC3R). Terbium 105-107 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus 155-158 26976869-7 2016 This study is the first comprehensive report to show the novel inhibitory potential of 22 marketed anti-TB drugs on OATP-mediated uptake, providing evidence for future in vivo clinical DDI studies. Terbium 104-106 solute carrier organic anion transporter family member 1A2 L homeolog Xenopus laevis 116-120 27293537-0 2016 Coupling the folding of a beta-hairpin with chelation-enhanced luminescence of Tb(III) and Eu(III) ions for specific sensing of a viral RNA. Terbium 79-81 amyloid beta precursor protein Homo sapiens 24-30 27127692-5 2016 RESULTS: SPF had significant positive correlations with trabecular bone structural parameters (BV/TV, BV, BS, BSD, Tb.Th, Tb.N, FD, and BS/BV) (P<0.01) while SPF demonstrated significant negative correlations with other microstructural parameters (Tb.Sp, Tb.Pf, and SMI) using micro-CT and CBCT (P<0.01). Terbium 115-117 SPF Sus scrofa 9-12 27127692-5 2016 RESULTS: SPF had significant positive correlations with trabecular bone structural parameters (BV/TV, BV, BS, BSD, Tb.Th, Tb.N, FD, and BS/BV) (P<0.01) while SPF demonstrated significant negative correlations with other microstructural parameters (Tb.Sp, Tb.Pf, and SMI) using micro-CT and CBCT (P<0.01). Terbium 122-124 SPF Sus scrofa 9-12 26889608-6 2016 Our finding that in Latvia, time to treatment initiation was decreased for MDR TB cases that were rifampin-resistant TB by XpertMTB/RIF has implications for the use of this test in other settings with a high burden of MDR TB in which rifampin resistance is highly predictive of MDR TB. Terbium 79-81 ras homolog family member F, filopodia associated Homo sapiens 132-135 27031950-5 2016 In addition, IL-22 but not IL-17 was produced by NK cells from PFCs in response to BCG and M.tb-related Ags. Terbium 93-95 interleukin 22 Homo sapiens 13-18 26959228-0 2016 Hierarchy Low CD4+/CD8+ T-Cell Counts and IFN-gamma Responses in HIV-1+ Individuals Correlate with Active TB and/or M.tb Co-Infection. Terbium 106-108 CD4 molecule Homo sapiens 14-17 26959228-0 2016 Hierarchy Low CD4+/CD8+ T-Cell Counts and IFN-gamma Responses in HIV-1+ Individuals Correlate with Active TB and/or M.tb Co-Infection. Terbium 106-108 CD8a molecule Homo sapiens 19-22 26959228-0 2016 Hierarchy Low CD4+/CD8+ T-Cell Counts and IFN-gamma Responses in HIV-1+ Individuals Correlate with Active TB and/or M.tb Co-Infection. Terbium 106-108 interferon gamma Homo sapiens 42-51 26959228-6 2016 Hierarchy low CD4+ T-cell counts (<200/muL, 200-500/muL, >500/muL) were correlated significantly with active TB but not M.tb co-infection. Terbium 115-117 CD4 molecule Homo sapiens 14-17 26959228-7 2016 Interestingly, hierarchy low CD8+ T-cell counts were not only associated significantly with active TB but also with M.tb co-infection (P<0.001). Terbium 99-101 CD8a molecule Homo sapiens 29-32 26959228-10 2016 CONCLUSIONS: Hierarchy low CD8+ T-cell counts and effector function in HIV-1-infected individuals are correlated with both M.tb co-infection and active TB. Terbium 152-154 CD8a molecule Homo sapiens 27-30 26959228-11 2016 Hierarchy low CD4+ T-cell counts and Th1 effector function in HIV-1+ individuals are associated with increased frequencies of active TB, but not M.tb co-infection. Terbium 133-135 CD4 molecule Homo sapiens 14-17 26901070-5 2016 Here, we show that the fluorescence emission and excitation spectra of the calcium luminescent analogue, Tb(3+), are enhanced upon binding to the EF-hands of DREAM due to a mechanism of energy transfer between Trp and Tb(3+). Terbium 105-107 potassium voltage-gated channel interacting protein 3 Homo sapiens 158-163 26901070-5 2016 Here, we show that the fluorescence emission and excitation spectra of the calcium luminescent analogue, Tb(3+), are enhanced upon binding to the EF-hands of DREAM due to a mechanism of energy transfer between Trp and Tb(3+). Terbium 218-220 potassium voltage-gated channel interacting protein 3 Homo sapiens 158-163 26901070-6 2016 We also observe that unlike Tb(3+)-bound calmodulin, the luminescence lifetime of terbium bound to DREAM decays as a complex multiexponential (tauaverage ~ 1.8 ms) that is sensitive to perturbation of the protein structure and drug (NS5806) binding. Terbium 82-89 potassium voltage-gated channel interacting protein 3 Homo sapiens 99-104 26901070-10 2016 Secondary structural analyses using far-UV circular dichroism and trapped ion mobility spectrometry-mass spectrometry reveal that replacement of Ca(2+) with Tb(3+) preserves the folding state with minimal changes to the overall structure of DREAM. Terbium 157-159 potassium voltage-gated channel interacting protein 3 Homo sapiens 241-246 26611774-8 2016 In contrast, TB-IRIS patients had significantly greater early increases in the frequency of tuberculosis-specific polyfunctional IFN-gamma(+)/IL-2(+)/TNF-alpha(+) CD4(+) T-cells on ART (P = .02); each quartile increase in the percentage of these cells was independently associated with a 2.8-fold increased risk of TB-IRIS (95% confidence interval, 1.1 to 7.5-fold). Terbium 13-15 interferon gamma Homo sapiens 129-138 26611774-8 2016 In contrast, TB-IRIS patients had significantly greater early increases in the frequency of tuberculosis-specific polyfunctional IFN-gamma(+)/IL-2(+)/TNF-alpha(+) CD4(+) T-cells on ART (P = .02); each quartile increase in the percentage of these cells was independently associated with a 2.8-fold increased risk of TB-IRIS (95% confidence interval, 1.1 to 7.5-fold). Terbium 13-15 interleukin 2 Homo sapiens 142-146 26611774-8 2016 In contrast, TB-IRIS patients had significantly greater early increases in the frequency of tuberculosis-specific polyfunctional IFN-gamma(+)/IL-2(+)/TNF-alpha(+) CD4(+) T-cells on ART (P = .02); each quartile increase in the percentage of these cells was independently associated with a 2.8-fold increased risk of TB-IRIS (95% confidence interval, 1.1 to 7.5-fold). Terbium 13-15 tumor necrosis factor Homo sapiens 150-159 26611774-8 2016 In contrast, TB-IRIS patients had significantly greater early increases in the frequency of tuberculosis-specific polyfunctional IFN-gamma(+)/IL-2(+)/TNF-alpha(+) CD4(+) T-cells on ART (P = .02); each quartile increase in the percentage of these cells was independently associated with a 2.8-fold increased risk of TB-IRIS (95% confidence interval, 1.1 to 7.5-fold). Terbium 13-15 CD4 molecule Homo sapiens 163-166 26951717-13 2016 CONCLUSION: Our findings suggest that activation markers, particularly CRP, may have a role in identifying good response to TB therapy regardless of the strain of infection and could be further developed as point-of-care tests. Terbium 124-126 C-reactive protein Homo sapiens 71-74 26638865-0 2016 Mycobacterium tuberculosis-specific CD4+ T-cell response is increased, and Treg cells decreased, in anthelmintic-treated patients with latent TB. Terbium 142-144 CD4 molecule Homo sapiens 36-39 26724769-6 2016 MAIT cells from patients with TB has significantly lower expression of gammac receptor than those from healthy controls under condition of Mtb lysates/IL-15 stimulation (p = 0.0028). Terbium 30-32 metallothionein 1J, pseudogene Homo sapiens 139-142 26724769-6 2016 MAIT cells from patients with TB has significantly lower expression of gammac receptor than those from healthy controls under condition of Mtb lysates/IL-15 stimulation (p = 0.0028). Terbium 30-32 interleukin 15 Homo sapiens 151-156 26872154-9 2016 Children with low 25-hydroxyvitamin D and TMEM 16J rs7111432-AA or PKP3 rs10902158-GG were at increased risk for probable/definite TB or death (aHR 8.12 and 4.83, p<0.05) and any TB or death (aHR 4.78 and 3.26, p<0.005) respectively; SNPs in VDBP, VDR, and vitamin D precursor or hydroxylation genes were not. Terbium 131-133 anoctamin 9 Homo sapiens 42-50 26628252-11 2016 A high level of agreement between the LOCI IFN-gamma method and T-SPOT.TB assay was observed in clinical studies that showed the LOCI IFN-gamma method could determine LTBI. Terbium 71-73 interferon gamma Homo sapiens 43-52 26628252-11 2016 A high level of agreement between the LOCI IFN-gamma method and T-SPOT.TB assay was observed in clinical studies that showed the LOCI IFN-gamma method could determine LTBI. Terbium 71-73 interferon gamma Homo sapiens 134-143 27158354-3 2016 Consistently, anti-TB drug treatment led to reduction in serum IL-35 level and p35 or EBI3 expression. Terbium 19-21 interleukin 12A Homo sapiens 79-82 27158354-3 2016 Consistently, anti-TB drug treatment led to reduction in serum IL-35 level and p35 or EBI3 expression. Terbium 19-21 Epstein-Barr virus induced 3 Homo sapiens 86-90 26872154-9 2016 Children with low 25-hydroxyvitamin D and TMEM 16J rs7111432-AA or PKP3 rs10902158-GG were at increased risk for probable/definite TB or death (aHR 8.12 and 4.83, p<0.05) and any TB or death (aHR 4.78 and 3.26, p<0.005) respectively; SNPs in VDBP, VDR, and vitamin D precursor or hydroxylation genes were not. Terbium 131-133 plakophilin 3 Homo sapiens 67-71 26872154-9 2016 Children with low 25-hydroxyvitamin D and TMEM 16J rs7111432-AA or PKP3 rs10902158-GG were at increased risk for probable/definite TB or death (aHR 8.12 and 4.83, p<0.05) and any TB or death (aHR 4.78 and 3.26, p<0.005) respectively; SNPs in VDBP, VDR, and vitamin D precursor or hydroxylation genes were not. Terbium 182-184 anoctamin 9 Homo sapiens 42-50 26815679-8 2016 The opposite was observed in the vertebra, where alpha2C-AR-/- mice show increased BV/TV, Tb.N and trabecular thickness (Tb.Th), and decreased Tb.Sp, compared with WT animals. Terbium 90-92 adrenergic receptor, alpha 2c Mus musculus 49-59 26518056-9 2016 IL-10 was significantly higher in untreated TB patients compared to contacts and controls (p < 0.0001). Terbium 44-46 interleukin 10 Homo sapiens 0-5 26815679-8 2016 The opposite was observed in the vertebra, where alpha2C-AR-/- mice show increased BV/TV, Tb.N and trabecular thickness (Tb.Th), and decreased Tb.Sp, compared with WT animals. Terbium 121-123 adrenergic receptor, alpha 2c Mus musculus 49-59 26797499-17 2016 We recommend a combination of LAM and SSM for TB diagnosis in HIV-infected patients with low CD4 counts in HIV/TB co-endemic countries, where alternative methods are unavailable. Terbium 46-48 CD4 molecule Homo sapiens 93-96 26542219-2 2015 In a sample set comprising 408 TB cases and 351 healthy controls, we show that the KIR3DS1 gene and KIR genotypes with five or more activating KIRs, and the presence of 3DS1, protect against developing active TB in the South African Coloured population. Terbium 31-33 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 Homo sapiens 83-86 26677868-4 2016 However, the addition of ALP destroys GMP-Tb shell, resulting in the release of Au-NPs from the shell into the solvent. Terbium 42-44 ATHS Homo sapiens 25-28 26497177-7 2016 Upon in vitro infection of PFMC CD4 T cells from TB mono-infected subjects, Nef- and/or Vpu-deleted HIV mutants showed lower generation of HIV-1 p24(+) DN T cells than the wild-type virus. Terbium 49-51 Nef Human immunodeficiency virus 1 76-79 26497177-7 2016 Upon in vitro infection of PFMC CD4 T cells from TB mono-infected subjects, Nef- and/or Vpu-deleted HIV mutants showed lower generation of HIV-1 p24(+) DN T cells than the wild-type virus. Terbium 49-51 Vpu Human immunodeficiency virus 1 88-91 26885516-0 2016 Identification of Novel RD1 Antigens and Their Combinations for Diagnosis of Sputum Smear-/Culture+ TB Patients. Terbium 100-102 phosphodiesterase 6B Homo sapiens 24-27 27012046-5 2016 RESULTS: The antigen-specific release of IP-10 in the TB group was significantly higher than in the non-tuberculous pulmonary disease group (p < 0.001) and the healthy control group (p < 0.001). Terbium 54-56 C-X-C motif chemokine ligand 10 Homo sapiens 41-46 27012046-6 2016 The IP-10 test correctly detected more cases of pulmonary TB and extra-pulmonary TB than the acid-fast staining microscopy examination (AFB). Terbium 58-60 C-X-C motif chemokine ligand 10 Homo sapiens 4-9 27012046-6 2016 The IP-10 test correctly detected more cases of pulmonary TB and extra-pulmonary TB than the acid-fast staining microscopy examination (AFB). Terbium 81-83 C-X-C motif chemokine ligand 10 Homo sapiens 4-9 27012046-8 2016 Patients with TB and cancer comorbidity produced significantly higher levels of the TB-specific IP-10 release compared to the other groups (p < 0.05), whereas respiratory disease patients produced lower levels than the healthy controls (p > 0.05). Terbium 14-16 C-X-C motif chemokine ligand 10 Homo sapiens 96-101 27012046-8 2016 Patients with TB and cancer comorbidity produced significantly higher levels of the TB-specific IP-10 release compared to the other groups (p < 0.05), whereas respiratory disease patients produced lower levels than the healthy controls (p > 0.05). Terbium 84-86 C-X-C motif chemokine ligand 10 Homo sapiens 96-101 27012046-9 2016 CONCLUSIONS: Our findings indicate high sensitivity and specificity of IP-10 as a novel biomarker for TB in China. Terbium 102-104 C-X-C motif chemokine ligand 10 Homo sapiens 71-76 26519973-6 2016 Correlations between TB traits and energy-corrected milk yield were estimated at the individual cow level. Terbium 21-23 Weaning weight-maternal milk Bos taurus 52-56 28042583-8 2016 The rate of positive QFT results and the levels of antigen-driven IFN-gamma secretion increased in a row: patients with residual TB lesions < patients with low TB activity < patients with high TB activity. Terbium 129-131 interferon gamma Homo sapiens 66-75 28042583-8 2016 The rate of positive QFT results and the levels of antigen-driven IFN-gamma secretion increased in a row: patients with residual TB lesions < patients with low TB activity < patients with high TB activity. Terbium 163-165 interferon gamma Homo sapiens 66-75 28042583-8 2016 The rate of positive QFT results and the levels of antigen-driven IFN-gamma secretion increased in a row: patients with residual TB lesions < patients with low TB activity < patients with high TB activity. Terbium 163-165 interferon gamma Homo sapiens 66-75 28042583-10 2016 The results suggest that quantitative parameters of IFN-gamma secretion play a minor role in determining the course of TB disease but mirror the activity of the infectious process. Terbium 119-121 interferon gamma Homo sapiens 52-61 27135844-11 2016 Although pleural TB usually occurs in male patients, middle-aged, as a unilateral exudative pleural effusion with lymphocytic predominance, with less than a month"s evolution, diagnostic certainty has its limitations, thus clinical suspicion, epidemiology, imaging, pathology and laboratory tests, and determination of adenosine deaminase levels, represent a valuable contribution to diagnosis. Terbium 17-19 adenosine deaminase Homo sapiens 319-338 26681217-6 2015 ROC curve was employed to evaluate the diagnostic value of miR-31 in pediatric TB. Terbium 79-81 microRNA 31 Homo sapiens 59-65 26681217-10 2015 The cut-off threshold of miR-31 for pediatric TB diagnosis is 0.835 with a sensitivity of 98.5% and a specificity of 86.7%. Terbium 46-48 microRNA 31 Homo sapiens 25-31 26728077-6 2016 Variants A and B bound Tb(3+) with high affinity (0.70 and 0.13 muM, respectively) and displayed restricted LBT motion. Terbium 23-25 latexin Homo sapiens 64-67 26621247-3 2016 Here we study the effect of the 5-HT2A receptor activation or blockade on Tb in sick animals. Terbium 74-76 5-hydroxytryptamine (serotonin) receptor 2A Mus musculus 32-47 26621247-11 2016 Thus, 5-HT2A receptors play a key role in Tb control in sick mice. Terbium 42-44 5-hydroxytryptamine (serotonin) receptor 2A Mus musculus 6-12 27238179-2 2016 Three major cytokines involved in TB immunopathogenesis include IL-2, IL-4 and IL-10. Terbium 34-36 interleukin 2 Homo sapiens 64-68 27238179-2 2016 Three major cytokines involved in TB immunopathogenesis include IL-2, IL-4 and IL-10. Terbium 34-36 interleukin 4 Homo sapiens 70-74 27238179-2 2016 Three major cytokines involved in TB immunopathogenesis include IL-2, IL-4 and IL-10. Terbium 34-36 interleukin 10 Homo sapiens 79-84 27238179-10 2016 Circulating IL-4 and IL-10 levels were significantly decreased whilst serum IL-2 level was significantly increased in patients with MDR TB compared to non-MDR TB. Terbium 136-138 interleukin 2 Homo sapiens 76-80 27238179-10 2016 Circulating IL-4 and IL-10 levels were significantly decreased whilst serum IL-2 level was significantly increased in patients with MDR TB compared to non-MDR TB. Terbium 159-161 interleukin 2 Homo sapiens 76-80 26631832-7 2016 After six months (M6) of anti-TB treatment (ATT) in HIV(-)TB(+) patients, IFN-gamma, IL-10, and MIP-1alpha levels normalized. Terbium 30-32 interferon gamma Homo sapiens 74-83 26631832-7 2016 After six months (M6) of anti-TB treatment (ATT) in HIV(-)TB(+) patients, IFN-gamma, IL-10, and MIP-1alpha levels normalized. Terbium 30-32 interleukin 10 Homo sapiens 85-90 26631832-7 2016 After six months (M6) of anti-TB treatment (ATT) in HIV(-)TB(+) patients, IFN-gamma, IL-10, and MIP-1alpha levels normalized. Terbium 30-32 C-C motif chemokine ligand 3 Homo sapiens 96-106 26631832-11 2016 In addition, IL-10 and MIP-1alpha levels could help to monitor responses to TB treatment and HAART. Terbium 76-78 interleukin 10 Homo sapiens 13-18 26631832-11 2016 In addition, IL-10 and MIP-1alpha levels could help to monitor responses to TB treatment and HAART. Terbium 76-78 C-C motif chemokine ligand 3 Homo sapiens 23-33 26786651-1 2016 BACKGROUND: The recently introduced IFN-gamma release assay (IGRA) has been reported to improve the diagnosis of TB. Terbium 113-115 interferon gamma Homo sapiens 36-45 26786651-13 2016 The other cytokine levels were not significantly differ between the 2 groups.From this study we concluded that TB antigen specific IL-1beta may be an additional biomarker for active TB diagnosis among HIV positive subjects. Terbium 111-113 interleukin 1 beta Homo sapiens 131-139 26786652-8 2016 However, only IP-10 could discriminate between TB and ORD, and this was significantly enhanced by analysing the site of infection (pleural fluid), which showed 92% correct classification. Terbium 47-49 C-X-C motif chemokine ligand 10 Homo sapiens 14-19 26422601-1 2015 The salen-type ligand prepared with (R,R) diphenylethan-1,2-diamine and salicylaldehyde provides stable and inert complexes KLnL2 upon simple reaction with lanthanide halides or pseudohalides LnX3 (Ln = Tb(3+) -Lu(3+) ; X = Cl(-) or TfO(-) ) of its potassium salt. Terbium 203-205 PDZ domain containing ring finger 3 Homo sapiens 192-196 26614187-5 2015 TB-specific antigen stimulated IP-10 levels were more profoundly increased in infected groups than in controls (P < 0.001 for all comparisons). Terbium 0-2 C-X-C motif chemokine ligand 10 Homo sapiens 31-36 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 218-220 arginine vasopressin Mus musculus 167-170 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 218-220 oxytocin Mus musculus 172-175 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 218-220 beta-2 microglobulin Mus musculus 177-180 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 218-220 CCR4-NOT transcription complex, subunit 7 Mus musculus 206-211 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 218-220 proprotein convertase subtilisin/kexin type 6 Mus musculus 225-230 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 218-220 repulsive guidance molecule family member A Mus musculus 232-236 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 218-220 RB transcriptional corepressor 1 Mus musculus 251-254 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 218-220 carboxypeptidase B2 (plasma) Mus musculus 260-264 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 243-245 arginine vasopressin Mus musculus 167-170 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 243-245 oxytocin Mus musculus 172-175 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 243-245 beta-2 microglobulin Mus musculus 177-180 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 243-245 CCR4-NOT transcription complex, subunit 7 Mus musculus 206-211 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 243-245 proprotein convertase subtilisin/kexin type 6 Mus musculus 225-230 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 243-245 repulsive guidance molecule family member A Mus musculus 232-236 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 243-245 RB transcriptional corepressor 1 Mus musculus 251-254 26611327-12 2015 Based on the literature, among the genes that ranked particularly high in our analyses (P < 10(-6)) and which have a validated causal role in skeletal biology, are Avp, Oxt, B2m (associated with BV/TV), Cnot7 (with Tb.N), Pcsk6, Rgma (with Tb.Th), Rb1, and Cpb2 (with Conn.D). Terbium 243-245 carboxypeptidase B2 (plasma) Mus musculus 260-264 26611327-13 2015 Other candidate genes strongly suggested by our analyses are Sgcz, Fgf20 (associated with Tb.N), and Chd2 (with Tb.Th). Terbium 90-92 fibroblast growth factor 20 Mus musculus 67-72 26611327-13 2015 Other candidate genes strongly suggested by our analyses are Sgcz, Fgf20 (associated with Tb.N), and Chd2 (with Tb.Th). Terbium 112-114 chromodomain helicase DNA binding protein 2 Mus musculus 101-105 27014741-3 2016 METHODS: We hypothesized that increases in matrix metalloproteinases (MMPs), which can degrade lung matrix, on ART are associated with TB-IRIS among a cohort of advanced, ART naive, HIV-infected adults with pTB. Terbium 135-137 matrix metallopeptidase 8 Homo sapiens 70-74 27014741-8 2016 Increases in CD4 counts and MMP-8 on ART were also associated with reduced forced expiratory volume in one-second post-TB treatment completion (r = - 0.7, p = 0.006 and r = - 0.6, p = 0.02, respectively; n = 14). Terbium 119-121 CD4 molecule Homo sapiens 13-16 27014741-8 2016 Increases in CD4 counts and MMP-8 on ART were also associated with reduced forced expiratory volume in one-second post-TB treatment completion (r = - 0.7, p = 0.006 and r = - 0.6, p = 0.02, respectively; n = 14). Terbium 119-121 matrix metallopeptidase 8 Homo sapiens 28-33 26567164-1 2015 BACKGROUND: Early death during TB treatment is associated with depressed TNFalpha response to antigenic stimulation and propensity to superadded bacterial infection. Terbium 31-33 tumor necrosis factor Homo sapiens 73-81 26567164-5 2015 RESULTS: Lower TB antigen-induced IL1beta (p = 0.006), TNFalpha (p = 0.02) and IL7 (p = 0.009) were produced in the poor outcome group. Terbium 15-17 interleukin 1 beta Homo sapiens 34-41 26567164-7 2015 Response to TB antigens correlated with responses to the purified TLR 2, 3 and 4 ligands. Terbium 12-14 toll like receptor 2 Homo sapiens 66-71 26518714-7 2015 We found a significant association between MCP-1 -2518 polymorphism and TB susceptibility only in the East Asian and Latin American groups (OR 3.47, P = 0.08; OR 2.73, P = 0.02). Terbium 72-74 C-C motif chemokine ligand 2 Homo sapiens 43-48 26979042-7 2015 So, we concluded that the abrupt cessation of anti-TNF agents after TB development could activate immune response causing paradoxical response, which lead to severe sequelae and death, and that continuation of anti-TNF therapy for rheumatoid arthritis in patients with active tuberculosis reactivated during anti-TNF medication is more beneficial than its cessation concerning not only clinical and radiological but also bacteriological outcomes. Terbium 68-70 tumor necrosis factor Homo sapiens 51-54 26542219-2 2015 In a sample set comprising 408 TB cases and 351 healthy controls, we show that the KIR3DS1 gene and KIR genotypes with five or more activating KIRs, and the presence of 3DS1, protect against developing active TB in the South African Coloured population. Terbium 31-33 killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1 Homo sapiens 83-90 26518714-9 2015 CONCLUSIONS: There is an association between MCP-1 -2518 polymorphism and TB susceptibility only in the East Asian and Latin American groups. Terbium 74-76 C-C motif chemokine ligand 2 Homo sapiens 45-50 26448780-10 2015 Increasing CD4 counts and antiretroviral treatment during TB treatment were protective against death. Terbium 58-60 CD4 molecule Homo sapiens 11-14 26509894-9 2015 The majority of TB testing occurs in the public sector, where significantly more providers prefer Xpert MTB/RIF assay, the designated clinical TB diagnostic tool by the national TB program, as compared to the private sector (87% versus 71%, p-value >0.0001). Terbium 16-18 ras homolog family member F, filopodia associated Homo sapiens 108-111 26359860-2 2015 We hypothesized that PD-1, PD-L1 and PD-L2 would be highly expressed in untreated tuberculosis patients compared to controls due to their chronic infection and would decrease with successful TB treatment. Terbium 191-193 MHC class I antigen 1 Sus scrofa 21-25 26245995-5 2015 RESULTS: The discrimination performance (assessed by the area under ROC curve) for IL-2 following stimulation with recombinant PE35 and PPE68 between LTBI and patients with active TB were 0.837 [95 % confidence interval (CI) 0.72-0.97] for LTBI diagnosis and 0.75 (95 % CI 0.63-0.89) for active TB diagnosis, respectively. Terbium 151-153 interleukin 2 Homo sapiens 83-87 26245995-5 2015 RESULTS: The discrimination performance (assessed by the area under ROC curve) for IL-2 following stimulation with recombinant PE35 and PPE68 between LTBI and patients with active TB were 0.837 [95 % confidence interval (CI) 0.72-0.97] for LTBI diagnosis and 0.75 (95 % CI 0.63-0.89) for active TB diagnosis, respectively. Terbium 180-182 interleukin 2 Homo sapiens 83-87 26245995-6 2015 Applying the 6.4 pg/mL cut-off for IL-2 induced by PE35 in the present study population resulted in sensitivity of 78 %, specificity of 83 %, PPV of 83 % and NPV of 78 % for the discrimination of active TB and LTBI. Terbium 203-205 interleukin 2 Homo sapiens 35-39 26441882-4 2015 This review focuses on the characteristics, functional expression, and modulation of known members of the MRP family in HIV infected cells exposed to ARV drugs and discusses their known role in drug-inefficacy in HIV/TB-induced dysfunctions. Terbium 217-219 ATP binding cassette subfamily C member 1 Homo sapiens 106-109 26441882-8 2015 Therefore, the prime objective of this review is to delineate the role of MRP transporters in HAART and TB therapy and their potential in precipitating cellular dysfunctions manifested in these chronic infectious diseases. Terbium 104-106 ATP binding cassette subfamily C member 1 Homo sapiens 74-77 25504009-1 2015 The main objective of the study was to evaluate whether in vitro QuantiFERON-TB Gold In-Tube (QFT-GIT) assay antigen-specific IL-1beta, TNF-alpha, IL-2, IL-6, IL-8 and IL-12 (p40) production is associated with active TB. Terbium 77-79 interleukin 1 beta Homo sapiens 126-134 25504009-1 2015 The main objective of the study was to evaluate whether in vitro QuantiFERON-TB Gold In-Tube (QFT-GIT) assay antigen-specific IL-1beta, TNF-alpha, IL-2, IL-6, IL-8 and IL-12 (p40) production is associated with active TB. Terbium 77-79 interleukin 2 Homo sapiens 147-151 25504009-9 2015 Our results suggest that antigen-specific IL-1beta can be used as a biomarker for active TB diagnosis as well as for differential diagnosis of PTB and LTBI. Terbium 89-91 interleukin 1 beta Homo sapiens 42-50 26151869-7 2015 The low cultivation temperature of 25 C, TB media (with 3% ethanol and 0.6M glycerol), Origami strain and a 10-h induction time increased the solubility of human growth hormone. Terbium 41-43 growth hormone 1 Homo sapiens 162-176 26245980-1 2015 We report on the synthesis of tridentate-nitrogen pyrazole-pyridine-tetrazole (L(1)H) and pyrazole-pyridine-triazole (L(2)H) ligands and their complexation with lanthanides (Ln = Gd(iii), Eu(iii) and Tb(iii)) resulting in stable, charge-neutral complexes Ln(L(1))3 and Ln(L(2))3, respectively. Terbium 200-202 immunoglobulin kappa variable 2-4 (pseudogene) Homo sapiens 255-264 26245980-1 2015 We report on the synthesis of tridentate-nitrogen pyrazole-pyridine-tetrazole (L(1)H) and pyrazole-pyridine-triazole (L(2)H) ligands and their complexation with lanthanides (Ln = Gd(iii), Eu(iii) and Tb(iii)) resulting in stable, charge-neutral complexes Ln(L(1))3 and Ln(L(2))3, respectively. Terbium 200-202 immunoglobulin kappa variable 1D-43 Homo sapiens 269-278 26359860-8 2015 The intensive phase of TB treatment was associated with a significant decline in PD-1, PD-L1 and PD-L2 gene expression. Terbium 23-25 MHC class I antigen 1 Sus scrofa 81-85 26359860-9 2015 PD-1 protein expression on the surface of NK cells, CD8+ and CD4+ T cells was similar in patients with active TB disease compared to controls but declined with successful TB treatment, with the greatest decline occurring on the NK cells followed by CD8+ T cells and then CD4+ T cells. Terbium 110-112 programmed cell death 1 Homo sapiens 0-4 26359860-11 2015 CONCLUSION: Modulation of PD-1/PD-L1 pathway through TB treatment indicates changes in the peripheral T cell response caused by live Mycobacterium tuberculosis (Mtb) followed by the response to dead bacilli, antigen-release and immuno-pathology resolution. Terbium 53-55 MHC class I antigen 1 Sus scrofa 26-30 26379827-11 2015 Markedly increased BV/TV and decreased Tb.Sp were observed in CT treated animals when compared with control animals. Terbium 39-41 calcitonin Cavia porcellus 62-64 26465516-6 2015 We illustrate that increasing the number of different parameters involved in the TB description, the fall of k(d) or k(N) becomes steeper and show the range covered by beta and eta. Terbium 81-83 endothelin receptor type A Homo sapiens 169-172 26322121-8 2015 CONCLUSIONS: Due to acceptable recoveries (93.3-102.0 %) and RSD values (6-7.1) from spiked tap water, the developed method can be successfully applied for the determination of trace amounts of terbium ions in the presence of major components of water. Terbium 194-201 nuclear RNA export factor 1 Homo sapiens 92-95 26096555-10 2015 Significantly reduced T1R3 mRNA expression, as measured by real-time RT-PCR, was observed in TB cells at 24h after application of DEX (0.1, 1.0, or 10muM). Terbium 93-95 taste 1 receptor member 3 Rattus norvegicus 22-26 26113434-1 2015 TB vaccine discovery has focused on IFN-gamma both for the selection of antigens and vaccine delivery strategies. Terbium 0-2 interferon gamma Homo sapiens 36-45 25919795-6 2015 Serum CT-1 levels exhibited a moderate positive correlation with the Scheuer stage of hepatic fibrosis and serum TB levels and a weak correlation with serum ALP levels. Terbium 113-115 cardiotrophin 1 Homo sapiens 6-10 26703340-12 2015 The suppression of IFN-gamma, TGF-beta or Th1/Th2 balance may be an important factor influencing the prognosis of TB. Terbium 114-116 interferon gamma Homo sapiens 19-28 26703340-12 2015 The suppression of IFN-gamma, TGF-beta or Th1/Th2 balance may be an important factor influencing the prognosis of TB. Terbium 114-116 transforming growth factor beta 1 Homo sapiens 30-38 26703340-12 2015 The suppression of IFN-gamma, TGF-beta or Th1/Th2 balance may be an important factor influencing the prognosis of TB. Terbium 114-116 negative elongation factor complex member C/D Homo sapiens 42-45 26286956-7 2015 The average Tb over the last 20 days was significantly related to the levels of body fat, structural tissue, leptin and insulin-like growth factor-1. Terbium 12-14 leptin Mus musculus 109-115 26286956-7 2015 The average Tb over the last 20 days was significantly related to the levels of body fat, structural tissue, leptin and insulin-like growth factor-1. Terbium 12-14 insulin-like growth factor 1 Mus musculus 120-148 26097915-1 2015 A mixed protonic and electronic conductor material BaCe(0.85)Tb(0.05)Zr(0.1)O(3-delta) (BCTZ) is prepared and a Ni-BCTZ cermet membrane is synthesized for hydrogen separation. Terbium 61-63 beta-secretase 1 Homo sapiens 51-55 26204836-1 2015 This article describes the genetically encoded caspase-3 FRET-sensor based on the terbium-binding peptide, cleavable linker with caspase-3 recognition site, and red fluorescent protein TagRFP. Terbium 82-89 caspase 3 Homo sapiens 47-56 26013160-4 2015 Significantly, the transmetalation of Co(II) or Ni(II) on the Zn(II) centers in 446-MOF can enhance the sorption capacities of CO2 and CH4 (16-21%), whereas the impregnation of Eu(III) and Tb(III) in the channels of 446-MOF will result in adjustable light-emitting behaviors. Terbium 189-191 mitochondrially encoded cytochrome c oxidase II Homo sapiens 38-44 25738572-6 2015 RESULTS: Median air conduction hearing thresholds using TB-ABR ranged from 0 to 20 dB nHL, depending on stimulus frequency. Terbium 56-58 regulator of telomere elongation helicase 1 Homo sapiens 86-89 25911222-1 2015 RATIONALE: Anti-tumour necrosis factor (TNF) agents and other anti-rheumatic medications increase the risk of TB in rheumatoid arthritis (RA). Terbium 110-112 tumor necrosis factor Homo sapiens 11-38 25911222-1 2015 RATIONALE: Anti-tumour necrosis factor (TNF) agents and other anti-rheumatic medications increase the risk of TB in rheumatoid arthritis (RA). Terbium 110-112 tumor necrosis factor Homo sapiens 40-43 25911222-8 2015 Individuals with TB or NTM disease were both more likely to be using anti-TNF therapy (compared with non-use); adjusted ORs (95% CIs) were 5.04 (1.27 to 20.0) and 2.19 (1.10 to 4.37), respectively. Terbium 17-19 tumor necrosis factor Homo sapiens 74-77 25911222-10 2015 CONCLUSIONS: Anti-TNF use is associated with increased risk of both TB and NTM disease, but appears to be a relatively greater risk for TB. Terbium 68-70 tumor necrosis factor Homo sapiens 18-21 25911222-10 2015 CONCLUSIONS: Anti-TNF use is associated with increased risk of both TB and NTM disease, but appears to be a relatively greater risk for TB. Terbium 136-138 tumor necrosis factor Homo sapiens 18-21 25756686-1 2015 The present paper reports on the results pertaining to photoluminescence properties of Tb(3+), Sm(3+) and energy transfer from Tb(3+) to Sm(3+) ions in lithium zinc phosphate (LZP) glass matrix prepared by melt quenching method. Terbium 87-89 oncoprotein induced transcript 3 Homo sapiens 176-179 25955974-0 2015 Green and blue emitting 3D structured Tb:Ce2(WO4)3 and Tb:Ce10W22O81 micromaterials. Terbium 38-40 carboxylesterase 2 Homo sapiens 41-44 25756686-1 2015 The present paper reports on the results pertaining to photoluminescence properties of Tb(3+), Sm(3+) and energy transfer from Tb(3+) to Sm(3+) ions in lithium zinc phosphate (LZP) glass matrix prepared by melt quenching method. Terbium 127-129 oncoprotein induced transcript 3 Homo sapiens 176-179 25756686-10 2015 The dipole-dipole interaction is found to be more responsible for energy transfer Tb(3+) ((5)D4) to Sm(3+) ((4)G5/2) ions in LZP glass matrix. Terbium 82-84 oncoprotein induced transcript 3 Homo sapiens 125-128 25801769-5 2015 iNOS (or NOS2) is a key enzyme for NO production and M.tb control during infection of mouse macrophages; however, the role of NO during infection of human macrophages remains unclear, in part, as a result of the low amounts of NO produced in these cells. Terbium 55-57 nitric oxide synthase 2, inducible Mus musculus 0-4 26100999-7 2015 Another important consideration is the risk of reactivation TB in patients with inflammatory bowel diseases which has been significantly increased following the widespread use of anti-Tumor Necrosis Factor Alpha (TNF-alpha) therapy. Terbium 60-62 tumor necrosis factor Homo sapiens 184-211 26100999-7 2015 Another important consideration is the risk of reactivation TB in patients with inflammatory bowel diseases which has been significantly increased following the widespread use of anti-Tumor Necrosis Factor Alpha (TNF-alpha) therapy. Terbium 60-62 tumor necrosis factor Homo sapiens 213-222 25801769-5 2015 iNOS (or NOS2) is a key enzyme for NO production and M.tb control during infection of mouse macrophages; however, the role of NO during infection of human macrophages remains unclear, in part, as a result of the low amounts of NO produced in these cells. Terbium 55-57 nitric oxide synthase 2, inducible Mus musculus 9-13 25801769-8 2015 The M.tb-induced iNOS expression and NO production are dependent on NOD2 expression during M.tb infection. Terbium 6-8 nitric oxide synthase 2 Homo sapiens 17-21 25801769-8 2015 The M.tb-induced iNOS expression and NO production are dependent on NOD2 expression during M.tb infection. Terbium 6-8 nucleotide binding oligomerization domain containing 2 Homo sapiens 68-72 25801769-8 2015 The M.tb-induced iNOS expression and NO production are dependent on NOD2 expression during M.tb infection. Terbium 93-95 nitric oxide synthase 2 Homo sapiens 17-21 25801769-8 2015 The M.tb-induced iNOS expression and NO production are dependent on NOD2 expression during M.tb infection. Terbium 93-95 nucleotide binding oligomerization domain containing 2 Homo sapiens 68-72 25996389-7 2015 The implementation of Xpert MTB/RIF was associated with increases in both notification rates of bacteriologically confirmed TB cases (adjusted incidence rate ratio [aIRR] 1.39; CI 1.18-1.64), and proportion of bacteriological confirmed TB cases among presumptive TB cases (adjusted risk ratio (aRR) 1.33; CI 1.6-1.52). Terbium 29-31 arrestin beta 1 Homo sapiens 282-300 25996389-7 2015 The implementation of Xpert MTB/RIF was associated with increases in both notification rates of bacteriologically confirmed TB cases (adjusted incidence rate ratio [aIRR] 1.39; CI 1.18-1.64), and proportion of bacteriological confirmed TB cases among presumptive TB cases (adjusted risk ratio (aRR) 1.33; CI 1.6-1.52). Terbium 124-126 ras homolog family member F, filopodia associated Homo sapiens 32-35 25996389-7 2015 The implementation of Xpert MTB/RIF was associated with increases in both notification rates of bacteriologically confirmed TB cases (adjusted incidence rate ratio [aIRR] 1.39; CI 1.18-1.64), and proportion of bacteriological confirmed TB cases among presumptive TB cases (adjusted risk ratio (aRR) 1.33; CI 1.6-1.52). Terbium 124-126 ras homolog family member F, filopodia associated Homo sapiens 32-35 25996389-11 2015 CONCLUSION: Introduction of Xpert MTB/RIF as initial diagnostic test for TB in public health facilities significantly increased case-notification rates of all bacteriologically confirmed TB by 39% and rifampicin-resistant TB case notification by fivefold. Terbium 73-75 ras homolog family member F, filopodia associated Homo sapiens 38-41 25658091-0 2015 Catching the missing million: experiences in enhancing TB & DR-TB detection by providing upfront Xpert MTB/RIF testing for people living with HIV in India. Terbium 67-69 ras homolog family member F, filopodia associated Homo sapiens 111-114 25747103-0 2015 Terbium doped SnO2 nanoparticles as white emitters and SnO2:5Tb/Fe3O4 magnetic luminescent nanohybrids for hyperthermia application and biocompatibility with HeLa cancer cells. Terbium 0-7 strawberry notch homolog 1 Homo sapiens 14-17 26075071-5 2015 The VDR Fok1 Ff genotype was associated with TB and the risk of PTB was two times higher in individuals with the Ff genotype. Terbium 45-47 vitamin D receptor Homo sapiens 4-7 26045845-1 2015 UNLABELLED: We conduct a case-control study to explore the possible association between IL-17 gene polymorphisms and development of TB. Terbium 132-134 interleukin 17A Homo sapiens 88-93 24633537-6 2015 In the histomorphometric evaluation, the high-dose UCN rats demonstrated an improved trabecular microarchitecture especially and significantly at the distal femur (distal femur Tb.Ar = 41.4% and N.Nd/mm(2) = 26.8, proximal femur Tb.Ar = 71.8% and N.Nd/mm(2) = 28.7) compared with untreated OVX rats (distal femur Tb.Ar = 23.3% and N.Nd/mm(2) = 11.7, proximal femur Tb.Ar = 60.2% and N.Nd/mm(2) = 25.2). Terbium 177-179 urocortin Rattus norvegicus 51-54 24633537-6 2015 In the histomorphometric evaluation, the high-dose UCN rats demonstrated an improved trabecular microarchitecture especially and significantly at the distal femur (distal femur Tb.Ar = 41.4% and N.Nd/mm(2) = 26.8, proximal femur Tb.Ar = 71.8% and N.Nd/mm(2) = 28.7) compared with untreated OVX rats (distal femur Tb.Ar = 23.3% and N.Nd/mm(2) = 11.7, proximal femur Tb.Ar = 60.2% and N.Nd/mm(2) = 25.2). Terbium 229-231 urocortin Rattus norvegicus 51-54 24633537-6 2015 In the histomorphometric evaluation, the high-dose UCN rats demonstrated an improved trabecular microarchitecture especially and significantly at the distal femur (distal femur Tb.Ar = 41.4% and N.Nd/mm(2) = 26.8, proximal femur Tb.Ar = 71.8% and N.Nd/mm(2) = 28.7) compared with untreated OVX rats (distal femur Tb.Ar = 23.3% and N.Nd/mm(2) = 11.7, proximal femur Tb.Ar = 60.2% and N.Nd/mm(2) = 25.2). Terbium 229-231 urocortin Rattus norvegicus 51-54 25565499-8 2015 Soluble(s) CD14 was increased in all patients with HIV/TB coinfection pre-ART and during TB-IRIS or equivalent time-point, compared with patients without TB. Terbium 55-57 CD14 molecule Homo sapiens 11-15 25565499-8 2015 Soluble(s) CD14 was increased in all patients with HIV/TB coinfection pre-ART and during TB-IRIS or equivalent time-point, compared with patients without TB. Terbium 89-91 CD14 molecule Homo sapiens 11-15 25686186-0 2015 ACP Journal Club: review: Xpert MTB/RIF assay detects extrapulmonary TB in lymph nodes and CSF, but not pleural fluid. Terbium 33-35 colony stimulating factor 2 Homo sapiens 91-94 25837441-8 2015 CONCLUSION: Substantial changes in TB-antigen-induced IFN-gamma and other cytokine responses during treatment likely primarily reflect host immunological changes rather than immunomodulatory effects of anti-tuberculous antibiotics. Terbium 35-37 interferon gamma Homo sapiens 54-63 25535219-4 2015 Rifampicin and rifapentine, two anti-TB drugs now being optimized to shorten TB treatment duration, are potent inducers of CYP3A4. Terbium 37-39 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 123-129 25535219-4 2015 Rifampicin and rifapentine, two anti-TB drugs now being optimized to shorten TB treatment duration, are potent inducers of CYP3A4. Terbium 77-79 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 123-129 25532942-5 2015 Using a RAS SNaPshot assay, HRAS mutations were detected in 2 (11%) of 18 sporadic TB and 6 (26%) of 23 sporadic syringocystadenoma papillifera. Terbium 83-85 HRas proto-oncogene, GTPase Homo sapiens 28-32 25532942-11 2015 Our results indicate that activation of the RAS-mitogen-activated protein kinase pathway by BRAF and RAS mutations contributes significantly to the tumorigenesis of sporadic SCAP and, less frequently, of sporadic TB. Terbium 213-215 B-Raf proto-oncogene, serine/threonine kinase Homo sapiens 92-96 25318864-10 2015 Each TSPOT(+) and TST(+) results were independently associated with immigrant status and prior residence in a TB prevalent country after adjustment for immunosuppressive therapy: Adjusted OR(TSPOT+)=6.6 (95 % CI, 1.2-123.3; P = .027); and adjusted OR(TST+)=11.2 (95 % CI, 2.0-209.5; P = .003). Terbium 110-112 thiosulfate sulfurtransferase Homo sapiens 18-21 25572425-4 2015 Genotypic and allelic distribution of TLR8 polymorphism (rs3764880) in patients with TB and healthy donors from different areas of southern Punjab, Pakistan, was determined. Terbium 85-87 toll like receptor 8 Homo sapiens 38-42 25572425-5 2015 Results provide that our population is highly influenced by TLR8 Met1Val SNP for TB, and G allele appeared to increase TB susceptibility. Terbium 81-83 toll like receptor 8 Homo sapiens 60-64 25572425-5 2015 Results provide that our population is highly influenced by TLR8 Met1Val SNP for TB, and G allele appeared to increase TB susceptibility. Terbium 119-121 toll like receptor 8 Homo sapiens 60-64 25318864-10 2015 Each TSPOT(+) and TST(+) results were independently associated with immigrant status and prior residence in a TB prevalent country after adjustment for immunosuppressive therapy: Adjusted OR(TSPOT+)=6.6 (95 % CI, 1.2-123.3; P = .027); and adjusted OR(TST+)=11.2 (95 % CI, 2.0-209.5; P = .003). Terbium 110-112 thiosulfate sulfurtransferase Homo sapiens 251-254 25406835-2 2015 We used a straightforward strategy to modify a known ALK substrate into a peptide biosensor that can accommodate terbium luminescence sensitization upon its phosphorylation by ALK. Terbium 113-120 ALK receptor tyrosine kinase Homo sapiens 53-56 25629611-8 2015 Immunofluorescence microscopy revealed altered punctate staining of Ikaros in TB splenocytes. Terbium 78-80 IKAROS family zinc finger 1 Mus musculus 68-74 25495521-5 2015 The decreases of decay lifetimes of host emissions in CNO:Eu(3+)/Tb(3+)/Dy(3+)/Sm(3+) demonstrate the energy transfer from the hosts to Eu(3+)/Tb(3+)/Dy(3+)/Sm(3+). Terbium 65-67 biogenesis of lysosomal organelles complex 1 subunit 4 Homo sapiens 54-57 25495521-5 2015 The decreases of decay lifetimes of host emissions in CNO:Eu(3+)/Tb(3+)/Dy(3+)/Sm(3+) demonstrate the energy transfer from the hosts to Eu(3+)/Tb(3+)/Dy(3+)/Sm(3+). Terbium 143-145 biogenesis of lysosomal organelles complex 1 subunit 4 Homo sapiens 54-57 25486415-7 2015 By week 34 post-TB treatment initiation, effector memory/central memory CD4 T-cell ratios were markedly higher in TB-IRIS versus non-TB-IRIS patients. Terbium 114-116 CD4 molecule Homo sapiens 72-75 25486415-7 2015 By week 34 post-TB treatment initiation, effector memory/central memory CD4 T-cell ratios were markedly higher in TB-IRIS versus non-TB-IRIS patients. Terbium 114-116 CD4 molecule Homo sapiens 72-75 25785121-9 2015 Meanwhile, treatment with IL-22 recombinant lentivirus reduced serum levels of TB, ALT, AST, ETM, and decreased MAD levels in rat liver tissues, but increased SOD levels in rat liver tissues. Terbium 79-81 interleukin 22 Rattus norvegicus 26-31 25406835-2 2015 We used a straightforward strategy to modify a known ALK substrate into a peptide biosensor that can accommodate terbium luminescence sensitization upon its phosphorylation by ALK. Terbium 113-120 ALK receptor tyrosine kinase Homo sapiens 176-179 25859975-6 2015 Here, we describe a TR-FRET assay that monitors the interaction of the estrogen receptor (ER) alpha ligand binding domain (labeled with a terbium chelate via a streptavidin-biotin interaction) with a sequence of coactivator protein SRC3 (labeled directly with fluorescein) and the disruption of this interaction with a peptide and a small molecule inhibitor. Terbium 138-145 nuclear receptor coactivator 3 Homo sapiens 232-236 25336752-10 2015 These studies demonstrate that transporters (Oatp, Bcrp/Mrp2), but not metabolism, contribute significantly to rat TB-2 hepatobiliary disposition. Terbium 115-117 ATP binding cassette subfamily C member 2 Rattus norvegicus 56-60 25866116-5 2015 Furthermore, there was a negative correlation between concentrations of miR-30A and beclin-1 in MTB positive patients and miR-30A expression decreased after anti-TB treatment. Terbium 97-99 microRNA 30a Homo sapiens 72-79 25866116-5 2015 Furthermore, there was a negative correlation between concentrations of miR-30A and beclin-1 in MTB positive patients and miR-30A expression decreased after anti-TB treatment. Terbium 97-99 microRNA 30a Homo sapiens 122-129 26435877-8 2015 TBP could be primary or secondary, may develop following circumcision performed by a person who had pulmonary Tb, and may be transmitted to the penis from ejaculation, contamination from clothing, or from contact with endometrial secretions, following an earlier pulmonary Tb or Tb elsewhere. Terbium 110-112 TATA-box binding protein Homo sapiens 0-3 26075097-3 2015 Abnormalities in BDNF signaling in the hippocampus could explain the cognitive decline seen in patients with TB. Terbium 109-111 brain derived neurotrophic factor Homo sapiens 17-21 26435877-8 2015 TBP could be primary or secondary, may develop following circumcision performed by a person who had pulmonary Tb, and may be transmitted to the penis from ejaculation, contamination from clothing, or from contact with endometrial secretions, following an earlier pulmonary Tb or Tb elsewhere. Terbium 273-275 TATA-box binding protein Homo sapiens 0-3 24771207-7 2014 3"-Deoxy-3"-(18) F-fluorothymidine ((18) F-FLT) positron emission tomography (PET) scans showed a remarkable decrease in (18) F-FLT signal in TC- and TB-treated OS-1 tumors, which was already noticeable after 1 week of treatment. Terbium 150-152 fms related receptor tyrosine kinase 1 Homo sapiens 43-46 24771207-7 2014 3"-Deoxy-3"-(18) F-fluorothymidine ((18) F-FLT) positron emission tomography (PET) scans showed a remarkable decrease in (18) F-FLT signal in TC- and TB-treated OS-1 tumors, which was already noticeable after 1 week of treatment. Terbium 150-152 fms related receptor tyrosine kinase 1 Homo sapiens 128-131 25209422-0 2014 Cytokine response to selected MTB antigens in Ghanaian TB patients, before and at 2 weeks of anti-TB therapy is characterized by high expression of IFN-gamma and Granzyme B and inter- individual variation. Terbium 31-33 interferon gamma Homo sapiens 148-157 25378475-2 2014 An eat-5 innexin mutant lacking this electrical connection has few TB contractions and is unable to grow well on certain foods. Terbium 67-69 Innexin eat-5 Caenorhabditis elegans 3-8 25171790-8 2014 At an ambient temperature (TA) of 24 C, all Pet1/DTR mice dropped their body temperature (TB) below 35 C after DT treatment, but the latency was shorter in males than females (3.0+-0.37 vs. 4.57+-0.29days, respectively; p<0.001). Terbium 90-92 plasmacytoma expressed transcript 1 Mus musculus 44-48 25171790-8 2014 At an ambient temperature (TA) of 24 C, all Pet1/DTR mice dropped their body temperature (TB) below 35 C after DT treatment, but the latency was shorter in males than females (3.0+-0.37 vs. 4.57+-0.29days, respectively; p<0.001). Terbium 90-92 heparin-binding EGF-like growth factor Mus musculus 49-52 25107461-8 2014 Induction of miR155 expression in cattle sourced from farms with confirmed bTB that tested positive in the tuberculin skin or interferon-gamma blood test was found to be significantly higher in cattle presenting with more advanced pathology (defined by the presence of visible TB lesions) compared to infected cattle without visible pathology and thus likely to be of lower infectivity than those with more advanced disease. Terbium 76-78 microRNA 155 Bos taurus 13-19 25092889-4 2014 CCR6(+)CXCR3(+)CCR4(-) cells display lineage-specific signatures of both Th1 and Th17 cells, but also have a unique gene expression program, including genes associated with susceptibility to TB, enhanced T cell activation, enhanced cell survival, and induction of a cytotoxic program akin to CTL cells. Terbium 191-193 C-C motif chemokine receptor 6 Homo sapiens 0-4 25092889-4 2014 CCR6(+)CXCR3(+)CCR4(-) cells display lineage-specific signatures of both Th1 and Th17 cells, but also have a unique gene expression program, including genes associated with susceptibility to TB, enhanced T cell activation, enhanced cell survival, and induction of a cytotoxic program akin to CTL cells. Terbium 191-193 C-C motif chemokine receptor 4 Homo sapiens 15-19 25459161-6 2014 Moreover, 1,25(OH)2D3 up regulated CAMP gene expression was more prominent in PTB patients without lung cavity (less severe form of disease) as compared to patients with cavitary TB (severe form of disease) (p < 0.05). Terbium 79-81 cathelicidin antimicrobial peptide Homo sapiens 35-39 27201798-0 2014 Different Strategies for Latent TB Assessment in Patients Undergoing Anti-TNF Treatment: an Economic Model. Terbium 32-34 tumor necrosis factor Homo sapiens 74-77 25131356-5 2014 The plasma TNF-alpha protein level was determined 10min before anesthesia (Ta), and 10min (Tb), 30min (Tc), and 60min (Td) after anesthesia by an enzyme-linked immunosorbent assay. Terbium 91-93 tumor necrosis factor Homo sapiens 11-20 25245058-4 2014 The spin glass behavior of Tb117Fe52Ge113.8(1) may be understood by assuming the presence of competing interactions among multiple non-equivalent Tb sites present in the highly complex unit cell. Terbium 27-29 spindlin 1 Homo sapiens 4-8 25092889-2 2014 In this study we show that TB-specific CD4(+) T cells have a characteristic chemokine expression signature (CCR6(+)CXCR3(+)CCR4(-)), and that the overall number of these cells is significantly increased in LTBI donors compared with healthy subjects. Terbium 27-29 C-C motif chemokine receptor 6 Homo sapiens 108-112 25092889-2 2014 In this study we show that TB-specific CD4(+) T cells have a characteristic chemokine expression signature (CCR6(+)CXCR3(+)CCR4(-)), and that the overall number of these cells is significantly increased in LTBI donors compared with healthy subjects. Terbium 27-29 C-C motif chemokine receptor 4 Homo sapiens 123-127 25209422-0 2014 Cytokine response to selected MTB antigens in Ghanaian TB patients, before and at 2 weeks of anti-TB therapy is characterized by high expression of IFN-gamma and Granzyme B and inter- individual variation. Terbium 31-33 granzyme B Homo sapiens 162-172 24909369-3 2014 The frequency of CD56(dim)CD16(+) NK cells that expressed ILT2 was significantly elevated in patients with active pulmonary TB as compared with tuberculin-positive healthy controls (p < 0.0001). Terbium 124-126 neural cell adhesion molecule 1 Homo sapiens 17-21 24993316-6 2014 At the present time whether a TB vaccine would work better if it targeted one specific T cell subset rather than another is as yet completely unknown, and this is now further complicated by new evidence that suggests other subsets such as IL-17 secreting CD4 T cells and cells with stem cell-like qualities may also play important roles. Terbium 30-32 interleukin 17A Homo sapiens 239-244 24780362-10 2014 ST patients had lower median CD4 counts at TB diagnosis than DT patients (106 vs. 278, p<0.001). Terbium 43-45 CD4 molecule Homo sapiens 29-32 24909369-3 2014 The frequency of CD56(dim)CD16(+) NK cells that expressed ILT2 was significantly elevated in patients with active pulmonary TB as compared with tuberculin-positive healthy controls (p < 0.0001). Terbium 124-126 Fc gamma receptor IIIa Homo sapiens 26-30 24909369-3 2014 The frequency of CD56(dim)CD16(+) NK cells that expressed ILT2 was significantly elevated in patients with active pulmonary TB as compared with tuberculin-positive healthy controls (p < 0.0001). Terbium 124-126 leukocyte immunoglobulin like receptor B1 Homo sapiens 58-62 24909369-8 2014 It is concluded that ILT2 has an inhibitory role on NK cells in patients with active TB. Terbium 85-87 leukocyte immunoglobulin like receptor B1 Homo sapiens 21-25 25105417-13 2014 Starting IPT-before-ART (aHR = 0.18, 95% CI = 0.08-0.42) or simultaneously with ART (aHR = 0.20, 95% CI = 0.10-0.42) provided further reduction of TB at ~ 80%. Terbium 147-149 tRNA isopentenyltransferase 1 Homo sapiens 9-12 25105417-14 2014 CONCLUSIONS: IPT was found to be effective in reducing TB incidence, independently and with concomitant ART, under programme conditions in resource-limited settings. Terbium 55-57 tRNA isopentenyltransferase 1 Homo sapiens 13-16 25105417-15 2014 The level of IPT provision and effectiveness in reducing TB was encouraging in the study setting. Terbium 57-59 tRNA isopentenyltransferase 1 Homo sapiens 13-16 25105417-16 2014 Scaling up and strengthening IPT service in addition to ART can have beneficial effect in reducing TB burden among PLHIV in settings with high TB/HIV burden. Terbium 99-101 tRNA isopentenyltransferase 1 Homo sapiens 29-32 24577604-0 2014 A TB antigen-stimulated CXCR3 ligand assay for the diagnosis of active pulmonary TB. Terbium 2-4 C-X-C motif chemokine receptor 3 Homo sapiens 24-29 24577604-0 2014 A TB antigen-stimulated CXCR3 ligand assay for the diagnosis of active pulmonary TB. Terbium 81-83 C-X-C motif chemokine receptor 3 Homo sapiens 24-29 24577604-8 2014 RESULTS: The TB antigen-stimulated levels of IFN-gamma, I-TAC, and MIG were significantly increased in the active pulmonary TB group compared with all other groups. Terbium 13-15 interferon gamma Homo sapiens 45-54 24577604-8 2014 RESULTS: The TB antigen-stimulated levels of IFN-gamma, I-TAC, and MIG were significantly increased in the active pulmonary TB group compared with all other groups. Terbium 13-15 C-X-C motif chemokine ligand 11 Homo sapiens 56-61 24577604-8 2014 RESULTS: The TB antigen-stimulated levels of IFN-gamma, I-TAC, and MIG were significantly increased in the active pulmonary TB group compared with all other groups. Terbium 13-15 C-X-C motif chemokine ligand 9 Homo sapiens 67-70 24577604-8 2014 RESULTS: The TB antigen-stimulated levels of IFN-gamma, I-TAC, and MIG were significantly increased in the active pulmonary TB group compared with all other groups. Terbium 124-126 interferon gamma Homo sapiens 45-54 24577604-8 2014 RESULTS: The TB antigen-stimulated levels of IFN-gamma, I-TAC, and MIG were significantly increased in the active pulmonary TB group compared with all other groups. Terbium 124-126 C-X-C motif chemokine ligand 11 Homo sapiens 56-61 24577604-8 2014 RESULTS: The TB antigen-stimulated levels of IFN-gamma, I-TAC, and MIG were significantly increased in the active pulmonary TB group compared with all other groups. Terbium 124-126 C-X-C motif chemokine ligand 9 Homo sapiens 67-70 24577604-10 2014 The areas under the curve (95% CI) for differentiating active pulmonary TB from all other groups were 0.893 (0.864-0.924) for IFN-gamma, 0.962 (0.946-0.978) for I-TAC, and 0.944 (0.922-0.965) for MIG. Terbium 72-74 interferon gamma Homo sapiens 126-135 24577604-12 2014 CONCLUSIONS: TB antigen-stimulated assays of I-TAC and MIG may be useful surrogate markers in the diagnosis of active pulmonary TB. Terbium 13-15 C-X-C motif chemokine ligand 11 Homo sapiens 45-50 24577604-12 2014 CONCLUSIONS: TB antigen-stimulated assays of I-TAC and MIG may be useful surrogate markers in the diagnosis of active pulmonary TB. Terbium 13-15 C-X-C motif chemokine ligand 9 Homo sapiens 55-58 24935214-4 2014 We developed and evaluated a recombinant replication-deficient human Ad5 vector expressing Ag85A (Ad5Ag85A) as a TB vaccine in animal models and a Phase I human study. Terbium 113-115 Alzheimer disease, familial, type 5 Homo sapiens 69-72 24935214-8 2014 Given its potency, Ad5-based TB vaccines are well-positioned to be delivered to the respiratory tract, induce local lung immunity to control TB, and inform innovative approaches to new TB vaccination strategies. Terbium 29-31 Alzheimer disease, familial, type 5 Homo sapiens 19-22 26307799-0 2014 TB: the tap"s down a notch - but the water"s polluted. Terbium 0-2 nuclear RNA export factor 1 Homo sapiens 8-12 25936121-6 2014 In luminance efficiency and external quantum efficiency, 1-PNAP-TB especially had superior property to NPB. Terbium 64-66 neuropeptide B Homo sapiens 103-106 25086966-7 2014 Pretreatment of the rats with anti-TNF-alpha antibody prevented the PSP-induced drop in Tb. Terbium 88-90 tumor necrosis factor Rattus norvegicus 35-44 25079599-11 2014 There was a decrease of 25 days (95% CI 17 to 32 days, p<0.001) in median MDR-TB treatment commencement time in the Xpert MTB/RIF-based algorithm. Terbium 81-83 metallothionein 1J, pseudogene Homo sapiens 125-128 25095750-7 2014 CONCLUSIONS: Antigen-reactive CD4+ T cells expressing CD39 are more abundant in active TB than LTBI and are associated with production of the immunosuppressive cytokine IL-10. Terbium 87-89 ectonucleoside triphosphate diphosphohydrolase 1 Homo sapiens 54-58 25095750-7 2014 CONCLUSIONS: Antigen-reactive CD4+ T cells expressing CD39 are more abundant in active TB than LTBI and are associated with production of the immunosuppressive cytokine IL-10. Terbium 87-89 interleukin 10 Homo sapiens 169-174 25079599-11 2014 There was a decrease of 25 days (95% CI 17 to 32 days, p<0.001) in median MDR-TB treatment commencement time in the Xpert MTB/RIF-based algorithm. Terbium 81-83 ras homolog family member F, filopodia associated Homo sapiens 129-132 23082947-9 2014 Staining for vimentin was positive in 7 (6%) of TB, 11 (11%) of IE, and 5 (5%) of LS specimens. Terbium 48-50 vimentin Homo sapiens 13-21 24458266-8 2014 Moreover, patients with coincident TB and T2DM exhibited increased plasma levels of TIMP-4 and elevated peripheral blood neutrophil counts, which, when considered together with HO-1, resulted in increased power to discriminate individuals with active TB with and without T2DM. Terbium 35-37 TIMP metallopeptidase inhibitor 4 Homo sapiens 84-90 24458266-8 2014 Moreover, patients with coincident TB and T2DM exhibited increased plasma levels of TIMP-4 and elevated peripheral blood neutrophil counts, which, when considered together with HO-1, resulted in increased power to discriminate individuals with active TB with and without T2DM. Terbium 35-37 heme oxygenase 1 Homo sapiens 177-181 26786336-9 2014 CONCLUSION: Changes in serum levels of nitrites and nitrates as well as iNOS activity in neutrophils may serve as diagnostic criteria to differentiate various clinical forms of TB and help as prognostic tool to predict treatment outcome. Terbium 177-179 nitric oxide synthase 2 Homo sapiens 72-76 24295645-2 2014 We discuss current screening methods and their limitations, the approach after positive screening and the timing to resume anti-TNFalpha treatment after TB infection. Terbium 153-155 tumor necrosis factor Homo sapiens 128-136 24222472-11 2014 Hypothalamic gene expression of orexigenic neuropeptides NPY and AgRP was higher, whereas expression of anorexigenic genes CCK and POMC were lower in TB compared to controls. Terbium 150-152 cholecystokinin Mus musculus 123-126 24222472-11 2014 Hypothalamic gene expression of orexigenic neuropeptides NPY and AgRP was higher, whereas expression of anorexigenic genes CCK and POMC were lower in TB compared to controls. Terbium 150-152 pro-opiomelanocortin-alpha Mus musculus 131-135 24222472-15 2014 CONCLUSIONS: Transcriptomic analysis of the hypothalamus of cachectic TB mice with an increased food intake showed changes in NPY, AgRP and serotonin signalling. Terbium 70-72 neuropeptide Y Mus musculus 126-129 24222472-15 2014 CONCLUSIONS: Transcriptomic analysis of the hypothalamus of cachectic TB mice with an increased food intake showed changes in NPY, AgRP and serotonin signalling. Terbium 70-72 agouti related neuropeptide Mus musculus 131-135 24786191-0 2014 Putting a terbium-monometallic cyanide cluster into the C82 fullerene cage: TbCN@C2(5)-C82. Terbium 10-17 complement C8 beta chain Homo sapiens 56-59 23082947-10 2014 Staining for Snail1 was positive in 83 (80%) of TB, 51 (49%) of IE, and 78 (75%) of LS specimens. Terbium 48-50 snail family transcriptional repressor 1 Homo sapiens 13-19 23082947-11 2014 Positive staining of TB for S100A4 (P = 0.04) and Snail1 at IE (P = 0.01) was associated with involvement of circumferential resection margins. Terbium 21-23 S100 calcium binding protein A4 Homo sapiens 28-34 23082947-12 2014 Positive staining for S100A4 in the TB (P = 0.02) and LS (P = 0.01) was associated with poor 5-year overall survival. Terbium 36-38 S100 calcium binding protein A4 Homo sapiens 22-28 24786191-0 2014 Putting a terbium-monometallic cyanide cluster into the C82 fullerene cage: TbCN@C2(5)-C82. Terbium 10-17 complement C8 beta chain Homo sapiens 87-90 24786191-1 2014 The first terbium (Tb)-monometallic cyanide clusterfullerene (CYCF), TbCN@C82, has been successfully synthesized and isolated, whose molecular structure was determined unambiguously as TbCN@C2(5)-C82 by single crystal X-ray diffraction. Terbium 10-17 complement C8 beta chain Homo sapiens 74-77 24786191-1 2014 The first terbium (Tb)-monometallic cyanide clusterfullerene (CYCF), TbCN@C82, has been successfully synthesized and isolated, whose molecular structure was determined unambiguously as TbCN@C2(5)-C82 by single crystal X-ray diffraction. Terbium 10-17 complement C8 beta chain Homo sapiens 196-199 24786191-1 2014 The first terbium (Tb)-monometallic cyanide clusterfullerene (CYCF), TbCN@C82, has been successfully synthesized and isolated, whose molecular structure was determined unambiguously as TbCN@C2(5)-C82 by single crystal X-ray diffraction. Terbium 19-21 complement C8 beta chain Homo sapiens 74-77 24786191-1 2014 The first terbium (Tb)-monometallic cyanide clusterfullerene (CYCF), TbCN@C82, has been successfully synthesized and isolated, whose molecular structure was determined unambiguously as TbCN@C2(5)-C82 by single crystal X-ray diffraction. Terbium 19-21 complement C8 beta chain Homo sapiens 196-199 24405814-1 2014 BACKGROUND: Tuberculosis is a major infectious disease and functional studies have provided evidence that both the chemokine MIP-1alpha and its receptor CCR5 play a role in susceptibility to TB. Terbium 191-193 C-C motif chemokine ligand 3 Homo sapiens 125-135 23906005-11 2014 CONCLUSIONS: Results suggest that sequence variants in TNC and COL5A1 genes are associated with SDF tendinopathy in TB racehorses. Terbium 116-118 tenascin C Equus caballus 55-58 23906005-11 2014 CONCLUSIONS: Results suggest that sequence variants in TNC and COL5A1 genes are associated with SDF tendinopathy in TB racehorses. Terbium 116-118 collagen type V alpha 1 chain Equus caballus 63-69 25007616-3 2014 The UV absorption spectra with same concentration show that the second ligand phen of Tb(2-FBA)3 phen absorbs the portion of the UV light instead of the first ligand 2-FBA. Terbium 86-88 F-box protein 3 Homo sapiens 91-94 25007616-3 2014 The UV absorption spectra with same concentration show that the second ligand phen of Tb(2-FBA)3 phen absorbs the portion of the UV light instead of the first ligand 2-FBA. Terbium 86-88 F-box protein 3 Homo sapiens 168-171 24226057-6 2014 MAIN RESULTS: TB IRIS occurred in 61 (7.6%) patients: 10.4% in earlier vs. 4.7% in later ART, 11.5% with CD4 <50 vs. 5.4% with CD4 >=50 cells per cubic millimeter. Terbium 14-16 CD4 molecule Homo sapiens 105-108 24226057-6 2014 MAIN RESULTS: TB IRIS occurred in 61 (7.6%) patients: 10.4% in earlier vs. 4.7% in later ART, 11.5% with CD4 <50 vs. 5.4% with CD4 >=50 cells per cubic millimeter. Terbium 14-16 CD4 molecule Homo sapiens 130-133 24226057-7 2014 The CD4/ART arm interaction was significant, P = 0.014, with 44.3% of TB IRIS occurring with CD4 <50 and earlier ART. Terbium 70-72 CD4 molecule Homo sapiens 4-7 24226057-7 2014 The CD4/ART arm interaction was significant, P = 0.014, with 44.3% of TB IRIS occurring with CD4 <50 and earlier ART. Terbium 70-72 CD4 molecule Homo sapiens 93-96 24778477-6 2014 STATISTICAL ANALYSIS: Sensitivity, specificity positive and negative predictive value of pleural fluid ADA for diagnosing TB was calculated by using clinical calculator - 1, Richard Lowry 2001-2013. Terbium 122-124 adenosine deaminase Homo sapiens 103-106 24778477-9 2014 Median ADA values for TB, malignancy and para pneumonic effusion were 55.8 U/l (range 9.7-756 U/l), 18 U/l (6.5-81 U/l) and 25 U/l (3.4-172 U/l) respectively. Terbium 22-24 adenosine deaminase Homo sapiens 7-10 24778477-12 2014 The median ADA for TB effusion in present cohort was 51.8 IU/ml. Terbium 19-21 adenosine deaminase Homo sapiens 11-14 24829762-9 2014 RESULTS: After inoculating VSSP into TB mice, a significant reduction of Arg1 and Nos2 gene expression was observed in recovered MDSCs. Terbium 37-39 arginase, liver Mus musculus 73-77 24829762-9 2014 RESULTS: After inoculating VSSP into TB mice, a significant reduction of Arg1 and Nos2 gene expression was observed in recovered MDSCs. Terbium 37-39 nitric oxide synthase 2, inducible Mus musculus 82-86 24269321-3 2014 Experiments in small animal models have indicated that broadening the immune response to include mycobacterial antigens other than Ag85A, such as Rv0288, induced by boosting with Ad5 constructs has a direct effect on the protection afforded against TB. Terbium 249-251 Alzheimer disease, familial, type 5 Homo sapiens 179-182 24412187-7 2014 TB ratio was correlated with immunohistochemistry of alphavbeta3 expression (LM609), macrophage density (CD68), and microvessel density (CD31) of the surgical specimen. Terbium 0-2 CD68 molecule Homo sapiens 105-109 24465778-5 2014 Anti-TB drug-induced liver injury (ATLI) was defined as an ALT, AST or bilirubin value more than twice the upper limit of normal. Terbium 5-7 solute carrier family 17 member 5 Homo sapiens 64-67 24831447-3 2014 Our objective is to report CD4 decline and changes in viral load (VL) in a group of HIV-infected adults enrolled in a randomized trial of preventive treatment for TB in South Africa where clade C infection predominates. Terbium 163-165 CD4 molecule Homo sapiens 27-30 23762936-1 2010 The activity of the probe compound was assessed by its ability to suppress Ubc13-mediated formation of heteropolymeric poly-ubquitination chains comprised of a mix of terbium-labeled and fluorescein-labeled ubiquitin molecules, as monitored by a reduction of the time-resolved fluorescent resonance energy transfer (TR-FRET) signal arising from this chains when synthesized in vitro in collaboration with the Ubc13 cofactor UEV1a. Terbium 167-174 ubiquitin conjugating enzyme E2 N Homo sapiens 75-80 24849439-10 2014 The serum levels of ACTH in the 3 groups all significantly increased at Tb and Tc (P<0.01). Terbium 72-74 proopiomelanocortin Homo sapiens 20-24 24849439-11 2014 CRP, IL-6 and TNF-a levels in group A were increased at Tb and Tc (P<0.05 or P<0.01) and significantly higher than those in groups B and C (P<0.05 or P<0.01). Terbium 56-58 C-reactive protein Homo sapiens 0-3 24849439-11 2014 CRP, IL-6 and TNF-a levels in group A were increased at Tb and Tc (P<0.05 or P<0.01) and significantly higher than those in groups B and C (P<0.05 or P<0.01). Terbium 56-58 tumor necrosis factor Homo sapiens 14-19 24849439-13 2014 ET-1 level in group C at Tb and Tc was lower than those in groups A and B (P<0.05 or P<0.01). Terbium 25-27 endothelin 1 Homo sapiens 0-4 24621055-3 2014 The aim of the present study was to assess the association between diabetes and Mycobacterium tuberculosis (Mtb) antigen-specific interferon gamma (IFN-gamma) release in a TB endemic area among culture-confirmed TB patients and non-TB controls. Terbium 172-174 interferon gamma Homo sapiens 80-157 24621055-3 2014 The aim of the present study was to assess the association between diabetes and Mycobacterium tuberculosis (Mtb) antigen-specific interferon gamma (IFN-gamma) release in a TB endemic area among culture-confirmed TB patients and non-TB controls. Terbium 212-214 interferon gamma Homo sapiens 80-157 24621055-9 2014 Although TB patients had higher specific and lower unspecific mitogen IFN-gamma responses compared to non-TB controls, the association between diabetes and IFN-gamma did not depend on TB status. Terbium 9-11 interferon gamma Homo sapiens 70-79 24650296-4 2014 Further, investigation of magnetically dilute samples containing 11-14 mol % of Tb(3+), Dy(3+), or U(3+) within the corresponding Y(3+) complex matrix reveals thermally activated relaxation is favored for the M(Bc(Me))3 complexes, even when dipolar interactions are largely absent. Terbium 80-82 malic enzyme 3 Homo sapiens 209-219 24705600-8 2014 People with smear-positive TB detected at the hospital were less likely to report cough lasting 2-3 weeks (RR 0.66 95%CI [0.49-0.90]) and more likely to report cough duration >3 weeks (RR 1.10 95%CI [1.03-1.18]). Terbium 27-29 ribonucleotide reductase catalytic subunit M1 Homo sapiens 188-192 24572497-3 2014 Fibrillin-1 binds to endothelial cells through an RGD cell adhesion motif in the fourth TB module. Terbium 88-90 fibrillin 1 Homo sapiens 0-11 24333340-3 2014 In our analysis of CD244 (2B4)-expressing cells in PBMCs from patients with active TB, a CD3(-)CD244(high) subpopulation was identified. Terbium 83-85 CD244 molecule Homo sapiens 19-24 24333340-3 2014 In our analysis of CD244 (2B4)-expressing cells in PBMCs from patients with active TB, a CD3(-)CD244(high) subpopulation was identified. Terbium 83-85 CD244 molecule Homo sapiens 95-100 24333340-6 2014 Patients with active TB had higher frequencies of CD3(-)CD244(high) cells as compared with healthy controls. Terbium 21-23 CD244 molecule Homo sapiens 56-61 24610960-0 2014 Synthesis and Luminescence Properties of Transparent Nanocrystalline GdF3:Tb Glass-Ceramic Scintillator. Terbium 74-76 growth differentiation factor 3 Homo sapiens 69-73 24610960-4 2014 The GdF3:Tb nanocrystals precipitated within the oxide glass matrix during the processing and their luminescence and scintillation properties were investigated. Terbium 9-11 growth differentiation factor 3 Homo sapiens 4-8 24356973-2 2014 To demonstrate application potentials, these bdk alcohols are used to chelate with various Lewis acids, including Tb (III), Eu (III), and B (III). Terbium 114-116 kininogen 1 Homo sapiens 45-48 24405814-1 2014 BACKGROUND: Tuberculosis is a major infectious disease and functional studies have provided evidence that both the chemokine MIP-1alpha and its receptor CCR5 play a role in susceptibility to TB. Terbium 191-193 C-C motif chemokine receptor 5 Homo sapiens 153-157 24405814-2 2014 Thus by measuring copy number variation of CCL3L1, one of the genes that encode MIP-1alpha, and genotyping a functional promoter polymorphism -2459A > G in CCR5 (rs1799987) we investigate the influence of MIP-1alpha and CCR5, independently and combined, in susceptibility to clinically active TB in three populations, a Peruvian population (n = 1132), a !Xhosa population (n = 605) and a South African Coloured population (n = 221). Terbium 296-298 C-C motif chemokine receptor 5 Homo sapiens 159-163 23982126-8 2014 Together, these results demonstrated the essential roles of AE-rMS-induced Th1-type responses, providing an effective treatment strategy by combining AE-rMS and RI for persistent TB. Terbium 179-181 negative elongation factor complex member C/D, Th1l Mus musculus 75-78 24516895-6 2014 Donor centromeric (c) and telomeric (t) KIR haplotype analysis showed that donor KIR cB-tA/tB was associated with improved OS and RFS compared with cA-tA or cA-tB. Terbium 91-93 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 Homo sapiens 40-43 24516895-6 2014 Donor centromeric (c) and telomeric (t) KIR haplotype analysis showed that donor KIR cB-tA/tB was associated with improved OS and RFS compared with cA-tA or cA-tB. Terbium 91-93 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 Homo sapiens 81-84 24136296-8 2014 Serum MMP-7 concentration was elevated in TB-IRIS and 2 weeks of corticosteroid therapy decreased this level, although not significantly. Terbium 42-44 matrix metallopeptidase 7 Homo sapiens 6-11 24172255-7 2013 HSP70 content in the small intestine was higher in the TB pigs than in C pigs. Terbium 55-57 heat shock 70 kDa protein 6 Sus scrofa 0-5 25424922-0 2014 Multivalent TB vaccines targeting the esx gene family generate potent and broad cell-mediated immune responses superior to BCG. Terbium 12-14 E74 like ETS transcription factor 3 Homo sapiens 38-41 25424922-2 2014 It is believed that the esx family of TB antigens may represent important vaccine candidates. Terbium 38-40 E74 like ETS transcription factor 3 Homo sapiens 24-27 23271427-1 2014 Patients with rheumatic disorders treated with TNF inhibitors are at increased risk of developing TB. Terbium 98-100 tumor necrosis factor Homo sapiens 47-50 24349220-10 2013 Our findings suggest that the four epitopes in CFP10 recognized by CD8(+) T cells might be of importance for the development of Mtb peptide-based vaccines and for improved diagnosis of TB in humans. Terbium 185-187 CD8a molecule Homo sapiens 67-70 24291065-0 2014 NOS2A promoter (CCTTT)n association with TB lacks independent functional correlation amongst Indians. Terbium 41-43 nitric oxide synthase 2 Homo sapiens 0-5 24379064-5 2013 In tuberculosis sputum culture, the serum concentrations of IL-10 and ESR in TB positive group were 0.045+-0.013 mg/L and 62.50+-8.69 mm/1h, significantly higher than that of TB negative group (p < 0.05); whereas, the concentrations of serum PCT and CRP in TB positive and negative groups had no significant difference (p > 0.05). Terbium 77-79 interleukin 10 Homo sapiens 60-65 24379064-5 2013 In tuberculosis sputum culture, the serum concentrations of IL-10 and ESR in TB positive group were 0.045+-0.013 mg/L and 62.50+-8.69 mm/1h, significantly higher than that of TB negative group (p < 0.05); whereas, the concentrations of serum PCT and CRP in TB positive and negative groups had no significant difference (p > 0.05). Terbium 77-79 C-reactive protein Homo sapiens 253-256 23943073-9 2013 Conversely, lymph node TB (OR = 0.2; 95 % CI 0.1-0.5) and skeletal TB (OR = 0.2; 95 % CI 0.1-0.5) were associated with true-positive TST results. Terbium 23-25 thiosulfate sulfurtransferase Homo sapiens 133-136 23943073-9 2013 Conversely, lymph node TB (OR = 0.2; 95 % CI 0.1-0.5) and skeletal TB (OR = 0.2; 95 % CI 0.1-0.5) were associated with true-positive TST results. Terbium 67-69 thiosulfate sulfurtransferase Homo sapiens 133-136 23999345-8 2013 In new, untreated cases, a higher degree of MDR-TB was observed at SA-1 (13.3%) and SA-3 (25.0%), whereas it was observed in only 7.1% of the isolates at SA-2. Terbium 48-50 stromal antigen 1 Homo sapiens 67-71 23684954-7 2013 Interestingly, some slices from AQP4 KO mice exhibited LTD after TBS instead of LTP, or LTP following LFS instead of LTD. Terbium 65-68 aquaporin 4 Mus musculus 32-36 24483486-7 2013 We find that eta(eff) decreases in the TT regime, passes a minimum at a critical lambda=lambda(c), and increases in the TB regime. Terbium 120-122 endothelin receptor type A Homo sapiens 13-16 24312369-6 2013 RESULTS: We observed lower baseline levels of IL-6 (p = 0.041), GCSF (p = 0.036) and LBP (p = 0.016) in TB-IRIS patients. Terbium 104-106 interleukin 6 Homo sapiens 46-50 24312369-6 2013 RESULTS: We observed lower baseline levels of IL-6 (p = 0.041), GCSF (p = 0.036) and LBP (p = 0.016) in TB-IRIS patients. Terbium 104-106 colony stimulating factor 3 Homo sapiens 64-68 24312369-6 2013 RESULTS: We observed lower baseline levels of IL-6 (p = 0.041), GCSF (p = 0.036) and LBP (p = 0.016) in TB-IRIS patients. Terbium 104-106 lipopolysaccharide binding protein Homo sapiens 85-88 24114827-4 2013 AIM: To investigate the possible association of anti-TB DIH with genetic polymorphism of GST genes in Western Indian population. Terbium 53-55 glutathione S-transferase kappa 1 Homo sapiens 89-92 24114827-9 2013 Homozygous null mutation in GSTM1 gene alone or in both GSTM1 and T1 genes was found to be significantly associated with anti-TB DIH at p < 0.02 and p < 0.007, respectively, in our study population. Terbium 126-128 glutathione S-transferase mu 1 Homo sapiens 28-33 24114827-9 2013 Homozygous null mutation in GSTM1 gene alone or in both GSTM1 and T1 genes was found to be significantly associated with anti-TB DIH at p < 0.02 and p < 0.007, respectively, in our study population. Terbium 126-128 glutathione S-transferase mu 1 Homo sapiens 56-61 24284535-3 2013 The social and health Association Naga in Milan with the Regional Reference Centre for TB, designed a screening system. Terbium 87-89 alpha-N-acetylgalactosaminidase Homo sapiens 34-38 26785981-3 2013 The use of adjunct biomarkers for TB diagnosis has been proposed, such as the chemokines: CXCL9, CXCL10 and CCL2. Terbium 34-36 C-X-C motif chemokine ligand 9 Homo sapiens 90-95 23913101-2 2013 The TB-SMA potential parameters for Pt-Ni nanoalloys are fitted to reproduce the results of density functional theory calculations for small clusters. Terbium 4-6 survival of motor neuron 1, telomeric Homo sapiens 7-10 24379064-5 2013 In tuberculosis sputum culture, the serum concentrations of IL-10 and ESR in TB positive group were 0.045+-0.013 mg/L and 62.50+-8.69 mm/1h, significantly higher than that of TB negative group (p < 0.05); whereas, the concentrations of serum PCT and CRP in TB positive and negative groups had no significant difference (p > 0.05). Terbium 175-177 interleukin 10 Homo sapiens 60-65 24379064-5 2013 In tuberculosis sputum culture, the serum concentrations of IL-10 and ESR in TB positive group were 0.045+-0.013 mg/L and 62.50+-8.69 mm/1h, significantly higher than that of TB negative group (p < 0.05); whereas, the concentrations of serum PCT and CRP in TB positive and negative groups had no significant difference (p > 0.05). Terbium 175-177 interleukin 10 Homo sapiens 60-65 24513672-6 2013 Donor centromeric (c) and telomeric (t) KIR haplotype analysis showed that donor KIR cB-tA/tB was associated with improved OS and RFS compared with cA-tA or cA-tB. Terbium 91-93 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 Homo sapiens 40-43 24513672-6 2013 Donor centromeric (c) and telomeric (t) KIR haplotype analysis showed that donor KIR cB-tA/tB was associated with improved OS and RFS compared with cA-tA or cA-tB. Terbium 91-93 killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 Homo sapiens 81-84 23286828-9 2013 For SD inhalation, deposition fractions of 20% were achieved in the lower TB region of B8-B15, which is a factor of 20-30xhigher than conventional delivery devices. Terbium 74-76 NADH:ubiquinone oxidoreductase subunit B4 Homo sapiens 90-93 22696093-0 2013 XDR TB in a case of IL12Rbeta1 deficiency: a case report of Mendelian Susceptibility to Mycobacterial Disease from India. Terbium 4-6 interleukin 12 receptor subunit beta 1 Homo sapiens 20-30 26785981-3 2013 The use of adjunct biomarkers for TB diagnosis has been proposed, such as the chemokines: CXCL9, CXCL10 and CCL2. Terbium 34-36 C-C motif chemokine ligand 2 Homo sapiens 108-112 26785981-5 2013 ESAT6-induced IFN-gamma responses were positive in 32% of TB cases as compared with 15% of EC cases (p=0.048). Terbium 58-60 interferon gamma Homo sapiens 14-23 26785981-6 2013 ESAT6-induced CXCL9 responses were positive in 42% of TB cases and 15% of EC cases (p=0.006). Terbium 54-56 C-X-C motif chemokine ligand 9 Homo sapiens 14-19 26785981-8 2013 Measurement of IFN-gamma or CXCL9 together diagnosed TB (53%) cases and was significant as compared with EC (p=0.014) cases. Terbium 53-55 interferon gamma Homo sapiens 15-24 26785981-8 2013 Measurement of IFN-gamma or CXCL9 together diagnosed TB (53%) cases and was significant as compared with EC (p=0.014) cases. Terbium 53-55 C-X-C motif chemokine ligand 9 Homo sapiens 28-33 26785981-10 2013 Within TB groups, ESAT6-IFN-gamma/CXCL9-based detection increased to 53% in PTB (p=0.031) and 54% in ETB (p=0.021), with comparable diagnosis in less severe extrapulmonary TB (L-ETB, 55%) and severe disseminated extrapulmonary TB (D-ETB, 50%). Terbium 7-9 interferon gamma Homo sapiens 24-33 26785981-10 2013 Within TB groups, ESAT6-IFN-gamma/CXCL9-based detection increased to 53% in PTB (p=0.031) and 54% in ETB (p=0.021), with comparable diagnosis in less severe extrapulmonary TB (L-ETB, 55%) and severe disseminated extrapulmonary TB (D-ETB, 50%). Terbium 7-9 C-X-C motif chemokine ligand 9 Homo sapiens 34-39 26785981-10 2013 Within TB groups, ESAT6-IFN-gamma/CXCL9-based detection increased to 53% in PTB (p=0.031) and 54% in ETB (p=0.021), with comparable diagnosis in less severe extrapulmonary TB (L-ETB, 55%) and severe disseminated extrapulmonary TB (D-ETB, 50%). Terbium 77-79 interferon gamma Homo sapiens 24-33 26785981-10 2013 Within TB groups, ESAT6-IFN-gamma/CXCL9-based detection increased to 53% in PTB (p=0.031) and 54% in ETB (p=0.021), with comparable diagnosis in less severe extrapulmonary TB (L-ETB, 55%) and severe disseminated extrapulmonary TB (D-ETB, 50%). Terbium 77-79 C-X-C motif chemokine ligand 9 Homo sapiens 34-39 26785981-10 2013 Within TB groups, ESAT6-IFN-gamma/CXCL9-based detection increased to 53% in PTB (p=0.031) and 54% in ETB (p=0.021), with comparable diagnosis in less severe extrapulmonary TB (L-ETB, 55%) and severe disseminated extrapulmonary TB (D-ETB, 50%). Terbium 77-79 interferon gamma Homo sapiens 24-33 26785981-10 2013 Within TB groups, ESAT6-IFN-gamma/CXCL9-based detection increased to 53% in PTB (p=0.031) and 54% in ETB (p=0.021), with comparable diagnosis in less severe extrapulmonary TB (L-ETB, 55%) and severe disseminated extrapulmonary TB (D-ETB, 50%). Terbium 77-79 C-X-C motif chemokine ligand 9 Homo sapiens 34-39 23790189-6 2013 CONCLUSION: This indicates that the genotypes obtained for CCL5 and IL-10 are associated with an increased risk of developing active TB. Terbium 133-135 C-C motif chemokine ligand 5 Homo sapiens 59-63 24034459-4 2013 OBJECTIVES: To determines the clinical and paraclinical characteristics of TB related to different levels of CD4 lymphocytes. Terbium 75-77 CD4 molecule Homo sapiens 109-112 23790189-6 2013 CONCLUSION: This indicates that the genotypes obtained for CCL5 and IL-10 are associated with an increased risk of developing active TB. Terbium 133-135 interleukin 10 Homo sapiens 68-73 23408601-6 2013 After adjustment for aBMD, men in the highest sclerostin quartile had higher Tb.vBMD (mainly in the central compartment) and Tb.N at both skeletal sites (p < 0.05 to 0.001). Terbium 77-79 sclerostin Homo sapiens 46-56 23408601-9 2013 Tb.vBMD increased across the sclerostin quartiles, and was associated with lower Tb.N and more heterogeneous trabecular distribution (higher Tb.Sp.SD) in men in the lowest sclerostin quartile. Terbium 0-2 sclerostin Homo sapiens 29-39 23408601-9 2013 Tb.vBMD increased across the sclerostin quartiles, and was associated with lower Tb.N and more heterogeneous trabecular distribution (higher Tb.Sp.SD) in men in the lowest sclerostin quartile. Terbium 0-2 sclerostin Homo sapiens 172-182 23408601-10 2013 After adjustment for aBMD, men in the lowest sclerostin quartile had lower Tb.vBMD and Tb.N, but higher Tb.Sp.SD (p < 0.05 to 0.001) at both the skeletal sites. Terbium 75-77 sclerostin Homo sapiens 45-55 23408601-10 2013 After adjustment for aBMD, men in the lowest sclerostin quartile had lower Tb.vBMD and Tb.N, but higher Tb.Sp.SD (p < 0.05 to 0.001) at both the skeletal sites. Terbium 87-89 sclerostin Homo sapiens 45-55 23408601-10 2013 After adjustment for aBMD, men in the lowest sclerostin quartile had lower Tb.vBMD and Tb.N, but higher Tb.Sp.SD (p < 0.05 to 0.001) at both the skeletal sites. Terbium 87-89 sclerostin Homo sapiens 45-55 23909356-2 2013 The device, a TbPc(2) single-molecule magnet spin transistor, detects the four different nuclear spin states of the Tb(3+) ion with fidelities better than 69%, allowing us to measure individual relaxation times (T(1)) of several tens of seconds. Terbium 14-16 spindlin 1 Homo sapiens 45-49 23909356-2 2013 The device, a TbPc(2) single-molecule magnet spin transistor, detects the four different nuclear spin states of the Tb(3+) ion with fidelities better than 69%, allowing us to measure individual relaxation times (T(1)) of several tens of seconds. Terbium 14-16 spindlin 1 Homo sapiens 97-101 23768819-7 2013 First, it reveals that the IL-10 (-592 A/A and -592 C/C) polymorphisms were found in a greater proportion in a group of patients with T2D and TB than in healthy subjects. Terbium 142-144 interleukin 10 Homo sapiens 27-32 23743311-11 2013 CONCLUSION: Increasing IP-10 and IL-6 production by BAL cells is associated with non-cavitary TB in patients who present with radiographically advanced TB. Terbium 94-96 C-X-C motif chemokine ligand 10 Homo sapiens 23-28 23743311-11 2013 CONCLUSION: Increasing IP-10 and IL-6 production by BAL cells is associated with non-cavitary TB in patients who present with radiographically advanced TB. Terbium 94-96 interleukin 6 Homo sapiens 33-37 23743311-11 2013 CONCLUSION: Increasing IP-10 and IL-6 production by BAL cells is associated with non-cavitary TB in patients who present with radiographically advanced TB. Terbium 152-154 C-X-C motif chemokine ligand 10 Homo sapiens 23-28 23743311-11 2013 CONCLUSION: Increasing IP-10 and IL-6 production by BAL cells is associated with non-cavitary TB in patients who present with radiographically advanced TB. Terbium 152-154 interleukin 6 Homo sapiens 33-37 23743311-12 2013 IP-10 and IL-6 may reflect an effective T-helper 1 immune control pathway for TB, attenuating tuberculous lung destruction. Terbium 78-80 C-X-C motif chemokine ligand 10 Homo sapiens 0-5 23743311-12 2013 IP-10 and IL-6 may reflect an effective T-helper 1 immune control pathway for TB, attenuating tuberculous lung destruction. Terbium 78-80 interleukin 6 Homo sapiens 10-14 23471623-3 2013 Therefore, a novel luminescent terbium chelates- (LTCs) and quantum dots-based homogeneous time-resolved fluorescence assay was developed to detect CEA. Terbium 31-38 CEA cell adhesion molecule 3 Homo sapiens 148-151 23782980-1 2013 BACKGROUND: It is estimated that Lao People"s Democratic Republic (Lao PDR) ranks fifth among the seven countries most affected by TB in the WHO Western Pacific Region. Terbium 131-133 interleukin 4 induced 1 Homo sapiens 33-36 23782980-1 2013 BACKGROUND: It is estimated that Lao People"s Democratic Republic (Lao PDR) ranks fifth among the seven countries most affected by TB in the WHO Western Pacific Region. Terbium 131-133 interleukin 4 induced 1 Homo sapiens 67-70 23624092-8 2013 These data suggest that IL-7-nFc as a novel TB adjuvant may facilitate therapeutic TB DNA vaccine to the clinics through significant enhancement of codelivered DNA vaccine-induced T cell immunity. Terbium 44-46 interleukin 7 Mus musculus 24-28 23624092-8 2013 These data suggest that IL-7-nFc as a novel TB adjuvant may facilitate therapeutic TB DNA vaccine to the clinics through significant enhancement of codelivered DNA vaccine-induced T cell immunity. Terbium 83-85 interleukin 7 Mus musculus 24-28 23977248-6 2013 Taken together, our data showed that the adjuvanted subunit and MVA strategies led to different T cell subset combinations pre and post infection and that TNF-alpha/IL-2 double producing but not IFN-gamma single producing CD4 T cell subsets correlated with protection in the mouse TB model. Terbium 281-283 tumor necrosis factor Mus musculus 155-164 23807270-12 2013 An intriguing possibility is that the development of TB-IRIS may depend partially on the relative balance between C1Q and C1-INH. Terbium 53-55 complement C1q A chain Homo sapiens 114-117 23807270-12 2013 An intriguing possibility is that the development of TB-IRIS may depend partially on the relative balance between C1Q and C1-INH. Terbium 53-55 serpin family G member 1 Homo sapiens 122-128 23874452-4 2013 In order to investigate the association between susceptibility to TB and genetic polymorphisms of the IFITM3 core promoter, a case-control study including 368 TB patients and 794 healthy controls was performed in Han Chinese children in northern China. Terbium 66-68 interferon induced transmembrane protein 3 Homo sapiens 102-108 23874452-10 2013 In conclusion, rs3888188, a functional promoter polymorphism of IFITM3, was identified to influence the risk for pediatric TB in Han Chinese population. Terbium 123-125 interferon induced transmembrane protein 3 Homo sapiens 64-70 23591749-1 2013 Isoniazid (INH) and rifampicin (RIF) are the first-line drugs for antituberculosis (anti-TB) chemotherapy. Terbium 89-91 alpha fetoprotein regulation 2, inducibility Mus musculus 32-35 23802647-9 2013 The decline of the prevalence of any form of metal disorder was 36.3% among TB/HIV co-infected patients compared to 19.4% among HIV patients without TB (P<0.001).QoL was strongly associated with CMD in TB/HIV co-infected patients and HIV patients without TB (beta = -0.04, P<0.001) after controlling the effect of several confounding variables such as sex, income, WHO disease stage, duration on ART, CD4 lymphocyte count, adherence to ART and social support. Terbium 76-78 CD4 molecule Homo sapiens 407-410 23826366-0 2013 Recombinant ESAT-6-CFP10 Fusion Protein Induction of Th1/Th2 Cytokines and FoxP3 Expressing Treg Cells in Pulmonary TB. Terbium 116-118 forkhead box P3 Homo sapiens 75-80 23840403-7 2013 RESULTS: Increase of CD4 T cell counts and suppression of HIV viral load were observed for all patients under HAART and TB treatment. Terbium 120-122 CD4 molecule Homo sapiens 21-24 23824716-6 2013 Th1 cytokines were significantly higher in TB-Treated, and the levels of IFN-gamma and TNF-alpha increased continuously after clinical cure. Terbium 43-45 negative elongation factor complex member C/D Homo sapiens 0-3 23824716-6 2013 Th1 cytokines were significantly higher in TB-Treated, and the levels of IFN-gamma and TNF-alpha increased continuously after clinical cure. Terbium 43-45 interferon gamma Homo sapiens 73-82 23824716-6 2013 Th1 cytokines were significantly higher in TB-Treated, and the levels of IFN-gamma and TNF-alpha increased continuously after clinical cure. Terbium 43-45 tumor necrosis factor Homo sapiens 87-96 23692474-4 2013 Here, the magnetic blocking in the series of isostructural 3d-4f complexes Co(II)-Ln(III)-Co(II), Ln = Gd, Tb, and Dy, is analyzed using an originally developed ab initio based approach for the investigation of blocking barriers. Terbium 107-109 mitochondrially encoded cytochrome c oxidase II Homo sapiens 90-96 23408601-6 2013 After adjustment for aBMD, men in the highest sclerostin quartile had higher Tb.vBMD (mainly in the central compartment) and Tb.N at both skeletal sites (p < 0.05 to 0.001). Terbium 125-127 sclerostin Homo sapiens 46-56 23856572-6 2013 Various modeling approaches were used to define IFN-gamma trajectories and correlations with TB exposure. Terbium 93-95 interferon gamma Homo sapiens 48-57 23646986-11 2013 Alternating current (ac) susceptibility measurements demonstrated that the Ni(II)-Tb(III) and Co(II)-Tb(III) complexes showed out-of-phase signal with frequency-dependence and the Ni(II)-Dy(III) and Co(II)-Dy(III) complexes showed small frequency-dependence. Terbium 82-84 mitochondrially encoded cytochrome c oxidase II Homo sapiens 199-205 23646986-12 2013 The energy barrier for the spin flipping was estimated from the Arrhenius plot to be 14.9(6) and 17.0(4) K for the Ni(II)-Tb(III) and Co(II)-Tb(III) complexes, respectively, under a dc bias field of 1000 Oe. Terbium 141-143 mitochondrially encoded cytochrome c oxidase II Homo sapiens 134-140 23278714-4 2013 OBJECTIVES: The aim of this study was to evaluate and compare the QuantiFERON( ) -TB Gold In-Tube (QFR) and T-SPOT.TB (TSTB) interferon-gamma-release assays (IGRA) against the TST in a cohort of patients commencing anti-TNF-alpha therapies for chronic inflammatory disease. Terbium 82-84 tumor necrosis factor Homo sapiens 220-229 23333588-5 2013 In this assay, fluorescently labeled leptin or leptin antagonist binds to the SNAP-tagged OB-R covalently labeled with terbium cryptate (Tb). Terbium 137-139 leptin receptor Homo sapiens 90-94 23272697-6 2013 In this work, we have combined the favorable characteristics of a terbium-ion-containing lanthanide-binding peptide (Tb(3+)-LBP) and green fluorescent protein (GFP) in a FRET-based homogeneous protease activity assay. Terbium 66-73 lipopolysaccharide binding protein Homo sapiens 124-127 23469989-3 2013 The aim of the present study was to explore the role of tagging single nucleotide polymorphisms (tSNPs) of CYP3A4, CYP2C9 and CYP2C19 in the risk of ATLI in a population-based anti-TB treatment cohort. Terbium 181-183 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 107-113 23638187-7 2013 Blockage of CD244/2B4 signaling pathway of T cells from patients with active TB resulted in significantly increased production of IFN-gamma, compared with isotype antibody control. Terbium 77-79 CD244 molecule Homo sapiens 12-17 23638187-7 2013 Blockage of CD244/2B4 signaling pathway of T cells from patients with active TB resulted in significantly increased production of IFN-gamma, compared with isotype antibody control. Terbium 77-79 interferon gamma Homo sapiens 130-139 23626814-9 2013 The concentrations of sIL-2R, IL-6, TNF-alpha, IFN-gamma in TB patients with or without COPD and COPD patients without TB were significantly higher than those in control group. Terbium 60-62 interferon gamma Homo sapiens 47-56 23626814-10 2013 In addition, sIL-2R, IL-6, TNF-alpha concentrations in the patients with TB and COPD were higher than those in the non-COPD TB patients. Terbium 73-75 tumor necrosis factor Homo sapiens 27-36 23626814-11 2013 The concentrations of sIL-2R, IL-6, TNF-alpha, IFN-gamma in COPD patients with TB were significantly higher than those in COPD patients without TB. Terbium 79-81 interleukin 6 Homo sapiens 30-34 23626814-11 2013 The concentrations of sIL-2R, IL-6, TNF-alpha, IFN-gamma in COPD patients with TB were significantly higher than those in COPD patients without TB. Terbium 79-81 tumor necrosis factor Homo sapiens 36-45 23626814-11 2013 The concentrations of sIL-2R, IL-6, TNF-alpha, IFN-gamma in COPD patients with TB were significantly higher than those in COPD patients without TB. Terbium 79-81 interferon gamma Homo sapiens 47-56 23626814-12 2013 There was a significant negative correlation between serum levels of TNF-alpha, IL-6 and FEV1 (%, predicted) in COPD without TB group. Terbium 125-127 tumor necrosis factor Homo sapiens 69-78 23593145-11 2013 CONCLUSIONS: Unlike previous studies, TST was the most cost-effective strategy for averting new TB cases in the short term. Terbium 96-98 thiosulfate sulfurtransferase Homo sapiens 38-41 23178506-4 2013 Single cytokines or chemokines predict with an area under the Receiver Operating Characteristic (ROC) curve of 0.59 for VEGF to 0.98 for IP 10 while a combination of fractalkine, IFN-g, IL-4, IP-10 and TNF identified 96.87% of TB cases and 100% of household contacts. Terbium 227-229 vascular endothelial growth factor A Homo sapiens 120-124 23429470-6 2013 Compared with the CNL group, TB mice have decreases in plasma Se concentrations and GPx activities, as well as higher plasma VEGF and MDA concentrations. Terbium 29-31 vascular endothelial growth factor A Mus musculus 125-129 23098285-8 2013 The mean TB volumes for CT1, CT2 and CT3 were 42.1 cm(3), 20.1 cm(3), 17.0 cm(3), respectively. Terbium 9-11 cardiotrophin 1 Homo sapiens 24-27 23098285-8 2013 The mean TB volumes for CT1, CT2 and CT3 were 42.1 cm(3), 20.1 cm(3), 17.0 cm(3), respectively. Terbium 9-11 cancer antigen 1 Homo sapiens 37-40 23098285-9 2013 The mean TB volume reduction was 40.5% from the CT1 to CT2 and 4.3% from the CT2 to CT3. Terbium 9-11 cardiotrophin 1 Homo sapiens 48-51 23098285-9 2013 The mean TB volume reduction was 40.5% from the CT1 to CT2 and 4.3% from the CT2 to CT3. Terbium 9-11 cancer/testis antigen 2 Homo sapiens 55-58 23098285-9 2013 The mean TB volume reduction was 40.5% from the CT1 to CT2 and 4.3% from the CT2 to CT3. Terbium 9-11 cancer/testis antigen 2 Homo sapiens 77-80 23098285-9 2013 The mean TB volume reduction was 40.5% from the CT1 to CT2 and 4.3% from the CT2 to CT3. Terbium 9-11 cancer antigen 1 Homo sapiens 84-87 23098285-10 2013 The difference of TB volumes between the CT1 and CT2 was statistically significance (p < 0.001), but not significant between the CT2 and CT3 (p = 1.000). Terbium 18-20 cardiotrophin 1 Homo sapiens 41-44 23098285-10 2013 The difference of TB volumes between the CT1 and CT2 was statistically significance (p < 0.001), but not significant between the CT2 and CT3 (p = 1.000). Terbium 18-20 cancer/testis antigen 2 Homo sapiens 49-52 23249609-4 2013 Intradermal immunization of HSP65-vaccine showed stronger therapeutic effect against TB than intramuscular or subcutaneous immunization. Terbium 85-87 heat shock protein 1 (chaperonin) Mus musculus 28-33 23539386-9 2013 CONCLUSION: Given the high risk of LTB reactivation in patients subjected to anti-TNF-alpha therapy, our results suggest that in our population, with low TB rate and very low BCG vaccination rate, both tests could be employed. Terbium 36-38 tumor necrosis factor Homo sapiens 82-91 23382842-0 2013 Interferon gamma release assays for the diagnosis of latent TB infection in HIV-infected individuals in a low TB burden country. Terbium 60-62 interferon gamma Homo sapiens 0-16 23374644-12 2013 Moderate or higher Cx46 expression (>20%) pre- and post-chemotherapy correlated with significantly better survival in the intermediate prognostic subgroups of EWGBSP TR2b (p(pre-chemo)=0.006; Sataloff TB (p(pre-chemo)=0.005; p(post-chemo)=0.029) and in Miller-Payne G3 (p(pre-chemo)=0.002; p(post-chemo)=0.012) classifications. Terbium 204-206 gap junction protein alpha 3 Homo sapiens 19-23 23073829-8 2013 Our results suggest that in female mice, Tb.BV and cortical bone volume are critically dependent on the ERalpha regulation of osteoblasts, whereas in male mice, osteoblastic ERalpha is not required for the regulation of bone formation during rapid skeletal growth, but it is involved in the maintenance of Tb.BV. Terbium 41-43 estrogen receptor 1 (alpha) Mus musculus 104-111 23266494-0 2013 Depletion of IL-22 during culture enhanced antigen-driven IFN-gamma production by CD4(+)T cells from patients with active TB. Terbium 122-124 interleukin 22 Homo sapiens 13-18 23266494-0 2013 Depletion of IL-22 during culture enhanced antigen-driven IFN-gamma production by CD4(+)T cells from patients with active TB. Terbium 122-124 interferon gamma Homo sapiens 58-67 23266494-0 2013 Depletion of IL-22 during culture enhanced antigen-driven IFN-gamma production by CD4(+)T cells from patients with active TB. Terbium 122-124 CD4 molecule Homo sapiens 82-85 23190413-4 2013 This study was designed to analyze the association between the NAT-2 and CYP2E1 polymorphisms with the development of anti-TB drug-induced hepatotoxicity (ATDH). Terbium 123-125 N-acetyltransferase 2 Homo sapiens 63-68 23190413-4 2013 This study was designed to analyze the association between the NAT-2 and CYP2E1 polymorphisms with the development of anti-TB drug-induced hepatotoxicity (ATDH). Terbium 123-125 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 73-79 23460870-3 2013 The present study was aimed at exploring the role of tSNPs in CYP2E1 gene in a population-based anti-TB treatment cohort. Terbium 101-103 cytochrome P450 family 2 subfamily E member 1 Homo sapiens 62-68 23178146-15 2013 Protein expression of IL-6 was increased 38% in TB MEAT (5.95 pg/mug), as compared with CT (3.64 pg/mug) and 50% compared with RTTB (2.91 pg/mug). Terbium 48-50 interleukin 6 Rattus norvegicus 22-26 23178146-17 2013 IL-10 protein expression was found to be increased in TB (4.4 pg/mug) and RTTB (3.2 pg/mug) 50% and 47%, respectively, in comparison with CT (1.2 pu/mug). Terbium 54-56 interleukin 10 Rattus norvegicus 0-5 23401703-3 2013 A simultaneous increase in the expression of the membrane bound mCD14 receptor and LFA-1 integrin in patients with active TB may be considered a prodrome of breaking immune control by M.tb bacilli in subjects with the latent TB and absence of clinical symptoms. Terbium 122-124 integrin subunit beta 2 Homo sapiens 83-88 23341869-10 2013 Lack of education (RR 1.85) and low CD4 count (CD4<=50 vs. >250cells/mm(3); RR 1.66) were associated with failed linkage to TB care. Terbium 130-132 CD4 molecule Homo sapiens 36-39 23341869-10 2013 Lack of education (RR 1.85) and low CD4 count (CD4<=50 vs. >250cells/mm(3); RR 1.66) were associated with failed linkage to TB care. Terbium 130-132 CD4 molecule Homo sapiens 47-50 22556318-0 2012 Monthly follow-ups of interferon-gamma release assays among health-care workers in contact with patients with TB. Terbium 110-112 interferon gamma Homo sapiens 22-38 23074705-0 2012 A sensitive strategy for label-free and time-resolved fluorescence assay of thrombin using Tb-complex and unmodified gold nanoparticles. Terbium 91-93 coagulation factor II, thrombin Homo sapiens 76-84 23074705-4 2012 The fluorescence intensity of Tb-complexes increases as the concentration of thrombin increases. Terbium 30-32 coagulation factor II, thrombin Homo sapiens 77-85 23074705-5 2012 Due to the highly specific recognition ability of the aptamer for thrombin and the strong quenching property of GNPs for Tb-complexes, the proposed protocol has good selectivity and high sensitivity for thrombin. Terbium 121-123 coagulation factor II, thrombin Homo sapiens 66-74 23074705-5 2012 Due to the highly specific recognition ability of the aptamer for thrombin and the strong quenching property of GNPs for Tb-complexes, the proposed protocol has good selectivity and high sensitivity for thrombin. Terbium 121-123 coagulation factor II, thrombin Homo sapiens 203-211 23252205-5 2012 They were analyzed to study sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), positive and negative likelihood ratios of BWRT-PCR TB on diagnostic tool for detecting pulmonary TB. Terbium 172-174 KCNQ1 downstream neighbor Homo sapiens 163-167 23032707-1 2012 The addition of allyl magnesium and allyl indium reagents to a key TBS protected norbornenyl building block, synthesised in 6-steps from commercially available 1,1-dimethoxy-2,3,4,5-tetrachlorocyclopentadiene, has been achieved providing the syn addition products with high diastereoselectivity. Terbium 67-70 synemin Homo sapiens 109-112 22258485-9 2012 CONCLUSIONS: Replacing TST with IGRA for determining LTBI allowed the proportion of patients with immune-mediated inflammatory diseases needing prophylactic anti-TB antibiotics before beginning anti-TNF agents to be reduced by half. Terbium 54-56 tumor necrosis factor Homo sapiens 199-202 22961735-5 2012 RESULTS: Active pulmonary TB generally showed an excess of TNF-alpha(+) subsets over IFN-gamma(+) subsets, paralleled by decreased CD27 expression on activated IFN-gamma(+) or CD154(+) CD4 T-cells. Terbium 26-28 tumor necrosis factor Homo sapiens 59-68 22961735-5 2012 RESULTS: Active pulmonary TB generally showed an excess of TNF-alpha(+) subsets over IFN-gamma(+) subsets, paralleled by decreased CD27 expression on activated IFN-gamma(+) or CD154(+) CD4 T-cells. Terbium 26-28 interferon gamma Homo sapiens 85-94 22961735-5 2012 RESULTS: Active pulmonary TB generally showed an excess of TNF-alpha(+) subsets over IFN-gamma(+) subsets, paralleled by decreased CD27 expression on activated IFN-gamma(+) or CD154(+) CD4 T-cells. Terbium 26-28 CD27 molecule Homo sapiens 131-135 22961735-5 2012 RESULTS: Active pulmonary TB generally showed an excess of TNF-alpha(+) subsets over IFN-gamma(+) subsets, paralleled by decreased CD27 expression on activated IFN-gamma(+) or CD154(+) CD4 T-cells. Terbium 26-28 CD40 ligand Homo sapiens 176-181 22961735-6 2012 The single subset distinguishing best between active pulmonary TB and high TB exposure was CD154(+) /TNF-alpha(+) / IFN-gamma(-) /IL-2(-) /degranulation(-) (AUROC 0.90). Terbium 63-65 CD40 ligand Homo sapiens 91-96 22961735-6 2012 The single subset distinguishing best between active pulmonary TB and high TB exposure was CD154(+) /TNF-alpha(+) / IFN-gamma(-) /IL-2(-) /degranulation(-) (AUROC 0.90). Terbium 63-65 tumor necrosis factor Homo sapiens 101-113 22961735-6 2012 The single subset distinguishing best between active pulmonary TB and high TB exposure was CD154(+) /TNF-alpha(+) / IFN-gamma(-) /IL-2(-) /degranulation(-) (AUROC 0.90). Terbium 63-65 interferon gamma Homo sapiens 116-128 22961735-6 2012 The single subset distinguishing best between active pulmonary TB and high TB exposure was CD154(+) /TNF-alpha(+) / IFN-gamma(-) /IL-2(-) /degranulation(-) (AUROC 0.90). Terbium 63-65 interleukin 2 Homo sapiens 130-137 22961735-6 2012 The single subset distinguishing best between active pulmonary TB and high TB exposure was CD154(+) /TNF-alpha(+) / IFN-gamma(-) /IL-2(-) /degranulation(-) (AUROC 0.90). Terbium 75-77 CD40 ligand Homo sapiens 91-96 22961735-6 2012 The single subset distinguishing best between active pulmonary TB and high TB exposure was CD154(+) /TNF-alpha(+) / IFN-gamma(-) /IL-2(-) /degranulation(-) (AUROC 0.90). Terbium 75-77 tumor necrosis factor Homo sapiens 101-113 22961735-6 2012 The single subset distinguishing best between active pulmonary TB and high TB exposure was CD154(+) /TNF-alpha(+) / IFN-gamma(-) /IL-2(-) /degranulation(-) (AUROC 0.90). Terbium 75-77 interferon gamma Homo sapiens 116-128 22961735-6 2012 The single subset distinguishing best between active pulmonary TB and high TB exposure was CD154(+) /TNF-alpha(+) / IFN-gamma(-) /IL-2(-) /degranulation(-) (AUROC 0.90). Terbium 75-77 interleukin 2 Homo sapiens 130-137 22990231-5 2012 In those with active TB, disease severity, time to sputum smear and culture conversion were correlated with VDR genotype and biochemical parameters. Terbium 21-23 vitamin D receptor Homo sapiens 109-112 22939121-5 2012 In the presence of target thrombin (TB), the TBA on the multilayer could catch the thrombin onto the electrode surface, which resulted in a barrier for electro-transfer, leading to the decrease of the electrochemical signal of Tb-Gra nanocomposites. Terbium 227-229 coagulation factor II, thrombin Homo sapiens 26-34 22863375-11 2012 CONCLUSION: In a TB-prevalent country, TST-defined LTBI diagnosis and treatment seem to be limited in preventing the development of TB before anti-TNF treatment. Terbium 17-19 tumor necrosis factor Homo sapiens 147-150 22863375-11 2012 CONCLUSION: In a TB-prevalent country, TST-defined LTBI diagnosis and treatment seem to be limited in preventing the development of TB before anti-TNF treatment. Terbium 52-54 tumor necrosis factor Homo sapiens 147-150 22872124-1 2012 Spin-wave excitations revealed in the dynamically equilibrated one-dimensional superlattices formed due to phase separation and charge carrier self-organization in doped single crystals of Eu(0.8)Ce(0.2)Mn(2)O(5) and Tb(0.95)Bi(0.05)MnO(3) multiferroics are discussed. Terbium 217-219 spindlin 1 Homo sapiens 0-4 22939121-5 2012 In the presence of target thrombin (TB), the TBA on the multilayer could catch the thrombin onto the electrode surface, which resulted in a barrier for electro-transfer, leading to the decrease of the electrochemical signal of Tb-Gra nanocomposites. Terbium 227-229 coagulation factor II, thrombin Homo sapiens 36-38 22939121-5 2012 In the presence of target thrombin (TB), the TBA on the multilayer could catch the thrombin onto the electrode surface, which resulted in a barrier for electro-transfer, leading to the decrease of the electrochemical signal of Tb-Gra nanocomposites. Terbium 227-229 coagulation factor II, thrombin Homo sapiens 83-91 22855746-0 2012 Rapid implementation of new TB diagnostic tests: is it too soon for a global roll-out of Xpert MTB/RIF? Terbium 28-30 ras homolog family member F, filopodia associated Homo sapiens 99-102 22622129-5 2012 To quantify autophagy, we reasoned that GFP-tagged LC3B could serve as a time-resolved fluorescence resonance energy transfer (TR-FRET) acceptor upon cell lysis in the presence of terbium-labeled LC3B antibodies. Terbium 180-187 microtubule associated protein 1 light chain 3 beta Homo sapiens 51-55 22622129-5 2012 To quantify autophagy, we reasoned that GFP-tagged LC3B could serve as a time-resolved fluorescence resonance energy transfer (TR-FRET) acceptor upon cell lysis in the presence of terbium-labeled LC3B antibodies. Terbium 180-187 microtubule associated protein 1 light chain 3 beta Homo sapiens 196-200 22404488-4 2012 In contrast no enhancements were observed in the presence of the oxidized form of glutathione (GSSG), except in the presence of the enzyme glutathione reductase and NADPH which enabled 1.Tb to be used to observe the enzymatic reduction of GSSG to GSH in real time. Terbium 187-189 glutathione-disulfide reductase Homo sapiens 139-160 22621208-1 2012 OBJECTIVE: To report on ampiginous choroiditis of tubercular etiology with nPCR positivity for M. tb in aqueous sample and also to stress upon the usefulness of nPCR to consolidate the etiological diagnosis. Terbium 98-100 nasopharyngeal carcinoma-related protein Homo sapiens 75-79 22542644-8 2012 The CD25/CD134 assay showed good agreement with QFN-GIT in detecting recall response to TB both in well and less resourced setting as well as in persons with advanced HIV infection. Terbium 88-90 interleukin 2 receptor subunit alpha Homo sapiens 4-8 22796839-0 2012 Challenges of interferon-gamma release assay conversions in serial testing of health-care workers in a TB control program. Terbium 103-105 interferon gamma Homo sapiens 14-30 22540161-5 2012 RESULTS: In spiked samples, TB-402 inhibited FVIII:C by 30%, prolonged APTT by 4.5 s, and reduced the peak height in the thrombin generation assay to 56% +- 13% of the control value. Terbium 28-30 coagulation factor VIII Homo sapiens 45-50 22540161-5 2012 RESULTS: In spiked samples, TB-402 inhibited FVIII:C by 30%, prolonged APTT by 4.5 s, and reduced the peak height in the thrombin generation assay to 56% +- 13% of the control value. Terbium 28-30 coagulation factor II, thrombin Homo sapiens 121-129 22540161-6 2012 In the presence of 10 mug mL(-1) TB-402, rhFVIII restored FVIII:C and APTT to the values obtained in the absence of TB-402. Terbium 33-35 coagulation factor VIII Homo sapiens 43-48 22792070-4 2012 The top signal mapping in the surroundings of WNT16 was replicated across studies with a meta-analysis P = 2.6 x 10(-31) and an effect size explaining between 0.6%-1.8% of TB-BMD variance. Terbium 172-174 Wnt family member 16 Homo sapiens 46-51 22542644-8 2012 The CD25/CD134 assay showed good agreement with QFN-GIT in detecting recall response to TB both in well and less resourced setting as well as in persons with advanced HIV infection. Terbium 88-90 TNF receptor superfamily member 4 Homo sapiens 9-14 22381458-6 2012 RESULTS: The levels of TB antigen specific IFN-gamma and IP-10 were significantly higher in HHC compared to HC. Terbium 23-25 interferon gamma Homo sapiens 43-52 22506966-0 2012 Inhibition of placenta growth factor with TB-403: a novel antiangiogenic cancer therapy. Terbium 42-44 placental growth factor Homo sapiens 14-36 22227965-2 2012 We reported previously that host defense against Mtb was impaired by hypercholesterolemia in ApoE(-/-) mice, raising the possibility that people with HC could be more vulnerable to TB. Terbium 181-183 non-SMC condensin II complex, subunit G2 Mus musculus 49-52 22416258-11 2012 Taken together, the present findings suggest that analysis of the expansion of CD4(+)IFN-gamma(+)IL-17(+) T lymphocytes in peripheral blood of TB patients might be used as an indicator of the clinical outcome in active TB. Terbium 143-145 interferon gamma Homo sapiens 85-94 22416258-11 2012 Taken together, the present findings suggest that analysis of the expansion of CD4(+)IFN-gamma(+)IL-17(+) T lymphocytes in peripheral blood of TB patients might be used as an indicator of the clinical outcome in active TB. Terbium 143-145 interleukin 17A Homo sapiens 97-102 22352469-2 2012 The targeted self-referencing luminescent thermometer Eu(0.0069)Tb(0.9931)-DMBDC (DMBDC = 2, 5-dimethoxy-1, 4-benzenedicarboxylate) based on two emissions of Tb(3+) at 545 nm and Eu(3+) at 613 nm is not only more robust, reliable, and instantaneous but also has higher sensitivity than the parent MOF Tb-DMBDC based on one emission at a wide range from 10 to 300 K. Terbium 64-66 lysine acetyltransferase 8 Homo sapiens 297-300 22754670-4 2012 COPD is surpassing Malaria, TB even today and the gap would get wider with time in near future. Terbium 28-30 COPD Homo sapiens 0-4 22571355-9 2012 Further, a reduction of magnitude in Tb decrease after repeated dosing of an antagonist suggests that TRPM8"s role in Tb maintenance may not pose an issue for developing TRPM8 antagonists as therapeutics. Terbium 118-120 transient receptor potential cation channel, subfamily M, member 8 Rattus norvegicus 102-107 22568711-6 2012 Determine TB-LAM is a simple, low-cost alternative to existing diagnostic assays for TB screening in HIV-infected patients with very low CD4(+) cell counts. Terbium 10-12 CD4 molecule Homo sapiens 137-140 22507941-0 2012 TB screening in an HIV clinic: how interferon-gamma assays improve screening compliance. Terbium 0-2 interferon gamma Homo sapiens 35-51 22138267-4 2012 The luminescence color emission of the synthesized particles could be tuned from red due to the effective (5)D(0) (7)F(j) (j=0, 1, 2 and 3) transitions within Eu(3+) to green due to the (5)D(4) (7)F(5) transition within Tb(3+) by switching the excitation wavelength from 255 to 310 nm. Terbium 220-222 immunoglobulin kappa joining 1 Homo sapiens 123-138 22745142-1 2012 AIM: to find whether there is a correlation between CD4+ count and TB form in TB-HIV Coinfected patients in Indonesia. Terbium 67-69 CD4 molecule Homo sapiens 52-55 22745142-9 2012 There was a very weak correlation between CD4+ count and TB form in TB-HIV patients in Indonesia (r=0.185; p=0.042). Terbium 57-59 CD4 molecule Homo sapiens 42-45 22745142-11 2012 After adjusting those factors, we found an increase on correlation between CD4+ count and TB form (r=0.353; p=0.000). Terbium 90-92 CD4 molecule Homo sapiens 75-78 22745142-12 2012 CONCLUSION: there was a correlation between CD4+ count and TB form in TB-HIV patients in Indonesia, but in a very weak correlation. Terbium 59-61 CD4 molecule Homo sapiens 44-47 21980060-0 2012 Performance of confirmatory interferon-gamma release assays in school TB outbreaks. Terbium 70-72 interferon gamma Homo sapiens 28-44 21980060-7 2012 Of the untreated groups, the rate of progression to TB was higher in the group with TST-positive (TST+) results (6.1%, six of 99) than in that with TST-negative (TST-) results (0.6%, 10 of 1,556; P < .001). Terbium 52-54 thiosulfate sulfurtransferase Homo sapiens 84-87 21980060-7 2012 Of the untreated groups, the rate of progression to TB was higher in the group with TST-positive (TST+) results (6.1%, six of 99) than in that with TST-negative (TST-) results (0.6%, 10 of 1,556; P < .001). Terbium 52-54 thiosulfate sulfurtransferase Homo sapiens 98-101 21980060-7 2012 Of the untreated groups, the rate of progression to TB was higher in the group with TST-positive (TST+) results (6.1%, six of 99) than in that with TST-negative (TST-) results (0.6%, 10 of 1,556; P < .001). Terbium 52-54 thiosulfate sulfurtransferase Homo sapiens 98-101 21980060-7 2012 Of the untreated groups, the rate of progression to TB was higher in the group with TST-positive (TST+) results (6.1%, six of 99) than in that with TST-negative (TST-) results (0.6%, 10 of 1,556; P < .001). Terbium 52-54 thiosulfate sulfurtransferase Homo sapiens 98-101 21980060-8 2012 Among TST+ contacts, the rate of progression to TB was higher in the group with QFT-G-positive (QFT-G+) results (18.75%, six of 32) than that with QFT-G-negative (QFT-G(-)) results (0%, 0 of 67; P = .001). Terbium 48-50 thiosulfate sulfurtransferase Homo sapiens 6-9 22504645-1 2012 Diagnosis of tuberculosis often relies on the ex vivo IFN-gamma release assays QuantiFERON-TB Gold In-Tube and T-SPOT.TB. Terbium 91-93 interferon gamma Homo sapiens 54-63 21465256-7 2012 The gene expression of MTP, and CPT I catalytic activity were reduced in TB, who also showed increased liver (150%) and plasma (3.3-fold) triacylglycerol content. Terbium 73-75 microsomal triglyceride transfer protein Rattus norvegicus 23-26 21465256-7 2012 The gene expression of MTP, and CPT I catalytic activity were reduced in TB, who also showed increased liver (150%) and plasma (3.3-fold) triacylglycerol content. Terbium 73-75 carnitine palmitoyltransferase 1A Rattus norvegicus 32-37 22213739-6 2012 Between January 2006 and December 2008, LiPA saved 25.3 and 32.2 days for TB diagnosis and rifampicin resistance of smear-positive samples, respectively. Terbium 74-76 lipase A, lysosomal acid type Homo sapiens 40-44 22120115-10 2012 Enumeration of spots in the TSPOT.TB assay demonstrated good agreement between CPT and T-Cell Xtend results, even after 48 h. CONCLUSIONS: T-Cell Xtend efficiently removes granulocytes from PBMC suspensions and increases the proportion of lymphocytes. Terbium 34-36 choline phosphotransferase 1 Homo sapiens 79-82 22668952-9 2012 The proportion of TB antigen (PPD)-specific CD4+IFN-gamma+ cells increased from 0.4% at baseline and 4 weeks (IRIS onset) to 7.8% at 12 weeks (after resolution of the IRIS episode); this fell to 0.7% at 24 weeks. Terbium 18-20 CD4 molecule Homo sapiens 44-47 22619880-12 2012 The prevalence of TB in Burmese, Lao and Cambodian workers was 1,119.3, 885.9 and 1,493.2 cases per 100,000 population respectively. Terbium 18-20 interleukin 4 induced 1 Homo sapiens 33-36 21923628-5 2012 RESULTS: Patients included at the beginning of treatment responded producing IFN-gamma after antigen stimulation in 89.7% by means of T-SPOT.TB and 79.3% by means of RD1 selected ELISPOT. Terbium 141-143 interferon gamma Homo sapiens 77-86 22369353-9 2012 The sensitivity of LAM for TB in HIV-infected patients with CD4 counts of >= 200, 100-199, 50-99, and < 50 cells/mul, was 15.2%, 32%, 42.9%, and 69.2% respectively. Terbium 27-29 CD4 molecule Homo sapiens 60-63 22120597-1 2012 OBJECTIVE: The purpose of this study was to examine the usefulness of the TST and the interferon-gamma release assays (IGRA) for diagnosing smear-negative pulmonary TB in immunocompromised patients in an intermediate TB burden. Terbium 165-167 thiosulfate sulfurtransferase Homo sapiens 74-77 22120597-1 2012 OBJECTIVE: The purpose of this study was to examine the usefulness of the TST and the interferon-gamma release assays (IGRA) for diagnosing smear-negative pulmonary TB in immunocompromised patients in an intermediate TB burden. Terbium 165-167 interferon gamma Homo sapiens 86-102 22442755-0 2012 Sub-optimal CD4 T-lymphocyte responses among HIV infected patients who develop TB during the first year of ART. Terbium 79-81 CD4 molecule Homo sapiens 12-15 22158781-8 2012 Rv2468c-induced costimulation of CD4+ T cells could have implications for TB immune pathogenesis and Mtb adjuvant effect. Terbium 74-76 CD4 molecule Homo sapiens 33-36 22431037-3 2012 The inhibition effect on tumorigenicity of subcutaneously challenged Tb cells in vaccinated Hu-PBL/SCID mice was detected.The expression of NKG2D and the cytotoxicity in vitro to Tb cells of peripheral blood mononuclear cells (PBMCs) and spleen cells were measured by flow cytometry and lactate dehydrogenase (LDH) release assay. Terbium 69-71 killer cell lectin-like receptor subfamily K, member 1 Mus musculus 140-145 22431037-5 2012 RESULTS: MICA gene modified Tb tumor vaccine resulted in remarkable loss of tumor size and tumor weight in vaccinated Hu-PBL/SCID mice. Terbium 28-30 inhibitor of carbonic anhydrase Mus musculus 9-13 22442755-10 2012 After adjustment for age, sex, baseline CD4 count and detectable viral load, patients with incident TB were found to have a 2.20 times greater odds of a sub-optimal CD4 response at 6 month of ART as compared to those who were TB free (95%CI: 1.14-4.23). Terbium 100-102 CD4 molecule Homo sapiens 40-43 22442755-10 2012 After adjustment for age, sex, baseline CD4 count and detectable viral load, patients with incident TB were found to have a 2.20 times greater odds of a sub-optimal CD4 response at 6 month of ART as compared to those who were TB free (95%CI: 1.14-4.23). Terbium 100-102 CD4 molecule Homo sapiens 165-168 22442755-11 2012 CONCLUSION: Incident TB was associated with a poor CD4 response during early ART in this cohort. Terbium 21-23 CD4 molecule Homo sapiens 51-54 22400104-10 2012 For patients starting ART after TB treatment, those with CD4 >= 50 cells/mm(3) were twice as likely to achieve treatment success (OR = 2.0, 95% CI = 1.3-3.1) compared to those with CD4 < 50 cells/mm(3). Terbium 32-34 CD4 molecule Homo sapiens 57-60 23080159-3 2012 The transient receptor potential vanilloid 1 (TRPV1) ion channel has been implicated in thermoregulation (Caterina et al., Science 288:306-313, 2000) and recently shown to exert a tonic effect on Tb in human subjects (Gavva et al., Pain 136:202-210, 2008). Terbium 196-198 transient receptor potential cation channel subfamily V member 1 Homo sapiens 4-44 23080159-3 2012 The transient receptor potential vanilloid 1 (TRPV1) ion channel has been implicated in thermoregulation (Caterina et al., Science 288:306-313, 2000) and recently shown to exert a tonic effect on Tb in human subjects (Gavva et al., Pain 136:202-210, 2008). Terbium 196-198 transient receptor potential cation channel subfamily V member 1 Homo sapiens 46-51 23080159-4 2012 We review herein the hypothesis that TRPV1 modulates the Tb response to hypoxia. Terbium 57-59 transient receptor potential cation channel subfamily V member 1 Homo sapiens 37-42 23080159-5 2012 We provide preliminary evidence that a 24 h hypoxia (FIO(2)=0.1) exposure caused an enhanced decrease in Tb in mutant TRPV1(-/-) mice compared to the TRPV1(+/+) genotype (Tb was >> 1 C lower than TRPV1(+/+)). Terbium 105-107 transient receptor potential cation channel, subfamily V, member 1 Mus musculus 118-123 22400104-10 2012 For patients starting ART after TB treatment, those with CD4 >= 50 cells/mm(3) were twice as likely to achieve treatment success (OR = 2.0, 95% CI = 1.3-3.1) compared to those with CD4 < 50 cells/mm(3). Terbium 32-34 CD4 molecule Homo sapiens 184-187 21778255-0 2012 IL-27 is elevated in patients with COPD and patients with pulmonary TB and induces human bronchial epithelial cells to produce CXCL10. Terbium 68-70 interleukin 27 Homo sapiens 0-5 22359719-6 2012 Reduced glutathione showed amelioration of ROS and TNF-alpha induced action, which in turn, subsequently suppressed the immune-bindings observed in monocytes of TB and SLE patients cultured without glutathione. Terbium 161-163 tumor necrosis factor Homo sapiens 51-60 23209372-5 2012 RESULTS: CA 125 and CA 15-3 levels were significantly high when compared with those of the healthy control group and there was a significant decrease in both tumor marker levels after treatment in patients with pulmonary TB (P < 0.001 and P < 0.004, respectively). Terbium 221-223 mucin 16, cell surface associated Homo sapiens 9-15 23209372-5 2012 RESULTS: CA 125 and CA 15-3 levels were significantly high when compared with those of the healthy control group and there was a significant decrease in both tumor marker levels after treatment in patients with pulmonary TB (P < 0.001 and P < 0.004, respectively). Terbium 221-223 mucin 1, cell surface associated Homo sapiens 20-27 23209372-7 2012 When the CA 125, CA 15-3, and CA 19-9 values of the pulmonary TB group before treatment were compared with that of the healthy control group, the results were statistically significant in all parameters except CA 19-9 (P < 0.001, P < 0.001, and P < 0.09 for CA 125, CA 15-3, and CA 19-9, respectively). Terbium 62-64 mucin 16, cell surface associated Homo sapiens 9-15 23209372-7 2012 When the CA 125, CA 15-3, and CA 19-9 values of the pulmonary TB group before treatment were compared with that of the healthy control group, the results were statistically significant in all parameters except CA 19-9 (P < 0.001, P < 0.001, and P < 0.09 for CA 125, CA 15-3, and CA 19-9, respectively). Terbium 62-64 mucin 1, cell surface associated Homo sapiens 17-24 23209372-7 2012 When the CA 125, CA 15-3, and CA 19-9 values of the pulmonary TB group before treatment were compared with that of the healthy control group, the results were statistically significant in all parameters except CA 19-9 (P < 0.001, P < 0.001, and P < 0.09 for CA 125, CA 15-3, and CA 19-9, respectively). Terbium 62-64 mucin 16, cell surface associated Homo sapiens 267-273 23209372-7 2012 When the CA 125, CA 15-3, and CA 19-9 values of the pulmonary TB group before treatment were compared with that of the healthy control group, the results were statistically significant in all parameters except CA 19-9 (P < 0.001, P < 0.001, and P < 0.09 for CA 125, CA 15-3, and CA 19-9, respectively). Terbium 62-64 mucin 1, cell surface associated Homo sapiens 275-282 23209372-9 2012 CONCLUSION: The authors suggest that CA 125 and CA 15-3 tumor markers may be important for verification of the success of treatment protocol in pulmonary TB, as the differences found for these tumor markers between the pre- and the posttreatment periods are statistically significant. Terbium 154-156 mucin 16, cell surface associated Homo sapiens 37-43 23209372-9 2012 CONCLUSION: The authors suggest that CA 125 and CA 15-3 tumor markers may be important for verification of the success of treatment protocol in pulmonary TB, as the differences found for these tumor markers between the pre- and the posttreatment periods are statistically significant. Terbium 154-156 mucin 1, cell surface associated Homo sapiens 48-55 23071578-5 2012 The ratio between secreted IFN-gamma/IL-10 and IL-2/IL-10 was significantly lower in TB-IRIS patients in whom the cause of TB was a drug-resistant strain compared to those with a fully sensitive strain (p = 0.02). Terbium 85-87 interferon gamma Homo sapiens 27-36 23272100-10 2012 Combining the QFT with IP-10 and IL-2 could increase the detection accuracy of active TB over the QFT alone. Terbium 86-88 C-X-C motif chemokine ligand 10 Homo sapiens 23-28 23272100-10 2012 Combining the QFT with IP-10 and IL-2 could increase the detection accuracy of active TB over the QFT alone. Terbium 86-88 interleukin 2 Homo sapiens 33-37 23071578-5 2012 The ratio between secreted IFN-gamma/IL-10 and IL-2/IL-10 was significantly lower in TB-IRIS patients in whom the cause of TB was a drug-resistant strain compared to those with a fully sensitive strain (p = 0.02). Terbium 85-87 interleukin 10 Homo sapiens 37-42 23071578-5 2012 The ratio between secreted IFN-gamma/IL-10 and IL-2/IL-10 was significantly lower in TB-IRIS patients in whom the cause of TB was a drug-resistant strain compared to those with a fully sensitive strain (p = 0.02). Terbium 85-87 interleukin 2 Homo sapiens 47-51 23071578-5 2012 The ratio between secreted IFN-gamma/IL-10 and IL-2/IL-10 was significantly lower in TB-IRIS patients in whom the cause of TB was a drug-resistant strain compared to those with a fully sensitive strain (p = 0.02). Terbium 85-87 interleukin 10 Homo sapiens 52-57 23071578-5 2012 The ratio between secreted IFN-gamma/IL-10 and IL-2/IL-10 was significantly lower in TB-IRIS patients in whom the cause of TB was a drug-resistant strain compared to those with a fully sensitive strain (p = 0.02). Terbium 123-125 interferon gamma Homo sapiens 27-36 23071578-5 2012 The ratio between secreted IFN-gamma/IL-10 and IL-2/IL-10 was significantly lower in TB-IRIS patients in whom the cause of TB was a drug-resistant strain compared to those with a fully sensitive strain (p = 0.02). Terbium 123-125 interleukin 10 Homo sapiens 37-42 23071578-5 2012 The ratio between secreted IFN-gamma/IL-10 and IL-2/IL-10 was significantly lower in TB-IRIS patients in whom the cause of TB was a drug-resistant strain compared to those with a fully sensitive strain (p = 0.02). Terbium 123-125 interleukin 2 Homo sapiens 47-51 23071578-5 2012 The ratio between secreted IFN-gamma/IL-10 and IL-2/IL-10 was significantly lower in TB-IRIS patients in whom the cause of TB was a drug-resistant strain compared to those with a fully sensitive strain (p = 0.02). Terbium 123-125 interleukin 10 Homo sapiens 52-57 22900099-8 2012 Overexpression of miR-3179, miR-147 and underexpression of miR-19b-2* in TB group compared with controls were confirmed in the validation cohort. Terbium 73-75 microRNA 19b-2 Homo sapiens 59-68 22761866-9 2012 However, due to concerns of reactivation disease, additional studies need to be performed before TNF-alpha inhibitors are used for TB treatment in humans. Terbium 131-133 tumor necrosis factor Homo sapiens 97-106 22844476-0 2012 The transcription factor NFATp plays a key role in susceptibility to TB in mice. Terbium 69-71 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 Mus musculus 25-30 22438899-9 2012 Squamous cell carcinoma (SCC) (55.8 vs. 31.7%, p<0.01) is a significant risk factor for NSCLC with active TB. Terbium 109-111 serpin family B member 3 Homo sapiens 25-28 21812801-8 2011 These results suggest that pUMVC6/PE35 may be useful as a safer vaccine candidate against TB. Terbium 90-92 PE family protein PE35 Mycobacterium tuberculosis H37Rv 34-38 22010133-2 2011 The C(3)-symmetric Delta and Lambda complexes of Eu and Tb are strongly emissive and can be resolved by chiral HPLC; the absolute configuration of each complex has been assigned using CD and CPL measurements. Terbium 56-58 hephaestin Homo sapiens 191-194 21879296-9 2011 CONCLUSION: PET has a high false-positive rate in areas with a high incidence of TB; combined PET and CT (PET/CT) can improve the diagnostic accuracy in the differentiation of an SPN. Terbium 81-83 DEAF1 transcription factor Homo sapiens 179-182 22006409-3 2011 A TB network for company doctors was created when interferon-gamma release assays (IGRAs) were introduced in order to systematically collate their experience with IGRAs in preventive check-ups. Terbium 2-4 interferon gamma Homo sapiens 50-66 21906820-7 2011 Finally, preliminary data from a longitudinal study of one M. bovis-exposed cat with a positive IFNgamma test pre-treatment suggest that a decrease in bacterial burden may be reflected in the IFNgamma response, and thus the IFNgamma test may provide a monitor for TB chemotherapy. Terbium 264-266 interferon gamma Felis catus 96-104 22761866-2 2012 We therefore evaluated whether adjunctive inhibition of tumor necrosis factor alpha (TNF-alpha)-a key cytokine in host responses against TB-could hasten bacterial clearance in a mouse strain that develops necrotic lesions in response to Mycobacterium tuberculosis infection. Terbium 137-139 tumor necrosis factor Mus musculus 56-83 22761866-2 2012 We therefore evaluated whether adjunctive inhibition of tumor necrosis factor alpha (TNF-alpha)-a key cytokine in host responses against TB-could hasten bacterial clearance in a mouse strain that develops necrotic lesions in response to Mycobacterium tuberculosis infection. Terbium 137-139 tumor necrosis factor Mus musculus 85-94 22761866-7 2012 CONCLUSION: This study provides proof-of-principle that modulation of TNF-alpha activity can hasten bacterial clearance during standard multi-drug TB treatment. Terbium 147-149 tumor necrosis factor Mus musculus 70-79 22761866-8 2012 Oral agents that modulate TNF-alpha should therefore be considered as adjunct therapies for shortening TB treatments. Terbium 103-105 tumor necrosis factor Mus musculus 26-35 22111973-8 2011 RESULTS: Higher percentages of apoptotic T cells and CD4 lymphocytes were isolated from children with acute phase CNS TB than from children in the control group (p < 0.05). Terbium 118-120 CD4 molecule Homo sapiens 53-56 22111973-13 2011 CONCLUSIONS: Our findings indicate that CNS TB in pediatric patients increases the sensitivity of CD4 and CD8+/CD28+ T cells to apoptosis, suggesting a hypoergic status of this infection. Terbium 44-46 CD4 molecule Homo sapiens 98-101 22111973-13 2011 CONCLUSIONS: Our findings indicate that CNS TB in pediatric patients increases the sensitivity of CD4 and CD8+/CD28+ T cells to apoptosis, suggesting a hypoergic status of this infection. Terbium 44-46 CD8a molecule Homo sapiens 106-109 22111973-13 2011 CONCLUSIONS: Our findings indicate that CNS TB in pediatric patients increases the sensitivity of CD4 and CD8+/CD28+ T cells to apoptosis, suggesting a hypoergic status of this infection. Terbium 44-46 CD28 molecule Homo sapiens 111-115 22109481-0 2011 1.92 Tb/s coherent DWDM-OFDMA-PON with no high-speed ONU-side electronics over 100 km SSMF and 1:64 passive split. Terbium 5-7 paraoxonase 1 Homo sapiens 30-33 22049429-4 2011 Moreover, radiolabeled Abeta administered at physiological concentrations into ISF revealed a striking difference in the fate of soluble Abeta in plaque-rich (vs plaque-free) mice: it clears more rapidly from the ISF and becomes more associated with the TBS-extractable pool, suggesting that cerebral amyloid deposits can rapidly sequester soluble Abeta from the ISF. Terbium 254-257 amyloid beta (A4) precursor protein Mus musculus 23-28 22049429-4 2011 Moreover, radiolabeled Abeta administered at physiological concentrations into ISF revealed a striking difference in the fate of soluble Abeta in plaque-rich (vs plaque-free) mice: it clears more rapidly from the ISF and becomes more associated with the TBS-extractable pool, suggesting that cerebral amyloid deposits can rapidly sequester soluble Abeta from the ISF. Terbium 254-257 amyloid beta (A4) precursor protein Mus musculus 137-142 22049429-4 2011 Moreover, radiolabeled Abeta administered at physiological concentrations into ISF revealed a striking difference in the fate of soluble Abeta in plaque-rich (vs plaque-free) mice: it clears more rapidly from the ISF and becomes more associated with the TBS-extractable pool, suggesting that cerebral amyloid deposits can rapidly sequester soluble Abeta from the ISF. Terbium 254-257 amyloid beta (A4) precursor protein Mus musculus 137-142 21969554-3 2011 Here we show that LM from virulent M.tb (TB-LM), but not from avirulent Myocobacterium smegmatis (SmegLM), is a potent inhibitor of TNF biosynthesis in human macrophages. Terbium 41-43 tumor necrosis factor Homo sapiens 132-135 21969554-5 2011 Rather, TB-LM stimulation leads to destabilization of TNF mRNA transcripts and subsequent failure to produce TNF protein. Terbium 8-10 tumor necrosis factor Homo sapiens 54-57 22256408-5 2011 Subjects diagnosed as latent TB infection by IFN-gamma assay (QuantiFERON-TB Gold In-Tube) were 5.9% of controls, 31.0% of casual contacts and 33.3% of close contacts. Terbium 74-76 interferon gamma Homo sapiens 45-54 21707929-8 2011 Though the present results suggest that the CCL5 gene haplotype A-C-C and the diplotype G/A-T/C may be associated with resistance to PTB, further studies with increased sample size may be useful to confirm this present finding as well as to understand the role of CCL5 haplotype and diplotype on genetic susceptibility to TB. Terbium 134-136 C-C motif chemokine ligand 5 Homo sapiens 44-48 21413978-0 2011 Predictors of indeterminate IFN-gamma release assay in screening for latent TB in inflammatory bowel diseases. Terbium 76-78 interferon gamma Homo sapiens 28-37 21785267-3 2011 We tested two of these Tb-bearing balancers (FM7-TbA and CyO-TbA) for more than 30 generations and found that the Tb1 transgene they carry is stable. Terbium 23-25 Sulfonylurea receptor Drosophila melanogaster 57-60 22338221-5 2011 The percentage of IL-17 before and after HAART were 1.90 +/- 0.9% vs. 4.65 +/- 1.48% respectively in HIV/TB group patients (P < 0.01). Terbium 105-107 interleukin 17A Homo sapiens 18-23 22145504-10 2011 The likelihood ratios (LHR) were higher in patients with CD4+ cell count over 200 cells/microL than for the HIV seronegative group (LHR+ 7.6 vs. 4.8 in an endogenous ICT-TB, and 2.5 vs. 1.9 in an exogenous ICT-TB). Terbium 210-212 CD4 molecule Homo sapiens 57-60 21419885-7 2011 Female mice of either WT(+/+) or Lrp5(-/-) genotype did not show significant strain:response curves for cortical or trabecular parameters, the one exception being Tb.Th in Lrp5(-/-) mice. Terbium 163-165 low density lipoprotein receptor-related protein 5 Mus musculus 172-176 21659613-5 2011 TMC207 has bactericidal and sterilizing activity in animal models of TB and improves the activity of current MDR-TB therapy in patients. Terbium 113-115 malic enzyme complex, mitochondrial Mus musculus 109-112 21645651-5 2011 LRP4 (rs6485702) was associated with higher total body (TB) and lumbar spine (LS) BMD in the PEAK-25 cohort (p=0.006 and 0.005 respectively), and interaction was observed with LRP5 (p=0.007) and BMP2 (p=0.004) for TB BMD. Terbium 56-58 LDL receptor related protein 4 Homo sapiens 0-4 22030588-0 2011 The establishment of bonds between professional and patient in TB treatment: the performance of primary health care services in a city in the interior of Sao Paulo. Terbium 63-65 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 154-157 22030588-1 2011 This study evaluated the performance of health care services implementing TB control actions in relation to the establishment of bonds between health professionals and patients in Sao Jose do Rio Preto, SP, Brazil from the perspective of patients, health professionals, and managers. Terbium 74-76 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 180-183 21726007-8 2011 In a second step, the activated Tb complex was used for the labelling of GFR44 monoclonal antibody, and was applied to the detection of carcinoembryonic antigene (CEA) within the frame of a time-resolved fluoroimmunoassay. Terbium 32-34 CEA cell adhesion molecule 3 Homo sapiens 136-161 21726007-8 2011 In a second step, the activated Tb complex was used for the labelling of GFR44 monoclonal antibody, and was applied to the detection of carcinoembryonic antigene (CEA) within the frame of a time-resolved fluoroimmunoassay. Terbium 32-34 CEA cell adhesion molecule 3 Homo sapiens 163-166 21642391-2 2011 Our aim was to analyze the association of the loss of TLR1 surface expression and TLR1 SNPs with susceptibility to TB. Terbium 115-117 toll like receptor 1 Homo sapiens 54-58 21933570-8 2011 However, R5 could significantly inhibit the motility, attachment and chemotaxis of Tb cells to FN, and it could also significantly inhibit the activity of MMP2 and MMP9 in Tb cells. Terbium 83-85 fibronectin 1 Homo sapiens 95-97 21642391-2 2011 Our aim was to analyze the association of the loss of TLR1 surface expression and TLR1 SNPs with susceptibility to TB. Terbium 115-117 toll like receptor 1 Homo sapiens 82-86 21642391-9 2011 Our data gain new insights in the role of TLR1 in M. tuberculosis defense and provide the first evidence that TLR1 variants are associated with susceptibility to TB in a low-incidence country. Terbium 162-164 toll like receptor 1 Homo sapiens 110-114 21640879-10 2011 The interleukin-6 concentration in the GCF at Tb was a significant predictive value for the GCF flow at T52 (P <0.05). Terbium 46-48 interleukin 6 Homo sapiens 4-17 21769770-11 2011 It further showed non-significant decreased (p >= 0.05) in the ALP levels between the zidovudine plus anti TB treated group (317.10 +- 73.48) and the zidovudine plus anti TB plus neutrosec treated group (203.20 +- 35.97). Terbium 110-112 PDZ and LIM domain 3 Rattus norvegicus 66-69 21420844-0 2011 Bronchoscopy in suspected pulmonary TB with negative induced-sputum smear and MTD( ) Gen-probe testing. Terbium 36-38 metallothionein 1E Homo sapiens 78-81 22041778-9 2011 The relative MRP mRNA level (3.45 +- 0.43) was the highest in the MDR-TB group (3.45 +- 0.43), as compared to the TB control group (1.23 +- 0.34) and the non-TB control group (1.04 +- 0.12), F = 24.241, P < 0.05. Terbium 70-72 ATP binding cassette subfamily C member 3 Homo sapiens 13-16 22041778-9 2011 The relative MRP mRNA level (3.45 +- 0.43) was the highest in the MDR-TB group (3.45 +- 0.43), as compared to the TB control group (1.23 +- 0.34) and the non-TB control group (1.04 +- 0.12), F = 24.241, P < 0.05. Terbium 114-116 ATP binding cassette subfamily C member 3 Homo sapiens 13-16 22041778-9 2011 The relative MRP mRNA level (3.45 +- 0.43) was the highest in the MDR-TB group (3.45 +- 0.43), as compared to the TB control group (1.23 +- 0.34) and the non-TB control group (1.04 +- 0.12), F = 24.241, P < 0.05. Terbium 114-116 ATP binding cassette subfamily C member 3 Homo sapiens 13-16 21701988-5 2011 RESULTS: In our study, mean ADA values in CSF were 28.34 +- 14.83 IU/L in TB cases, 8.71 +- 5.83 IU/L in BM, 6.18 +- 2.54 IU/L in PM and 3.43 +- 3.48 U/L in AM cases. Terbium 74-76 adenosine deaminase Homo sapiens 28-31 21701988-11 2011 If we accept an ADA activity cut-off level of 11 IU/L for differential diagnosis of TB and non-TB by applying ROC analysis, its sensitivity was 92% and specificity was 90%. Terbium 84-86 adenosine deaminase Homo sapiens 16-19 21701988-11 2011 If we accept an ADA activity cut-off level of 11 IU/L for differential diagnosis of TB and non-TB by applying ROC analysis, its sensitivity was 92% and specificity was 90%. Terbium 95-97 adenosine deaminase Homo sapiens 16-19 21701988-12 2011 CONCLUSION: The sensitivity and specificity for CSF ADA activity are markedly high in differential diagnosis of TB from non-TB. Terbium 112-114 adenosine deaminase Homo sapiens 52-55 21701988-12 2011 CONCLUSION: The sensitivity and specificity for CSF ADA activity are markedly high in differential diagnosis of TB from non-TB. Terbium 124-126 adenosine deaminase Homo sapiens 52-55 21701988-13 2011 Hence CSF ADA activity may be used as a simple, cost-effective and reliable test for early differential diagnosis of TB. Terbium 117-119 adenosine deaminase Homo sapiens 10-13 21505297-10 2011 CONCLUSION: Patients with unmasking TB-IRIS had higher pre-ART levels of plasma IFN-gamma and CRP, consistent with preexisting subclinical TB. Terbium 36-38 interferon gamma Homo sapiens 80-89 21505297-10 2011 CONCLUSION: Patients with unmasking TB-IRIS had higher pre-ART levels of plasma IFN-gamma and CRP, consistent with preexisting subclinical TB. Terbium 36-38 C-reactive protein Homo sapiens 94-97 21595599-3 2011 The fact that TNF plays a role in the immune cell response and, more specifically, in maintenance of granuloma integrity is the accepted grounds for reactivation of TB following inhibition of TNF. Terbium 165-167 tumor necrosis factor Homo sapiens 14-17 21569377-9 2011 In summary, suppression of microglial MMP-2 secretion by M.tb-infected monocyte-dependent networks paradoxically involves the pro-inflammatory mediators TNF-alpha, p38 MAP kinase and NFkappaB in addition to a novel caspase 8-dependent pathway. Terbium 59-61 matrix metallopeptidase 2 Homo sapiens 38-43 21569377-9 2011 In summary, suppression of microglial MMP-2 secretion by M.tb-infected monocyte-dependent networks paradoxically involves the pro-inflammatory mediators TNF-alpha, p38 MAP kinase and NFkappaB in addition to a novel caspase 8-dependent pathway. Terbium 59-61 tumor necrosis factor Homo sapiens 153-162 21569377-9 2011 In summary, suppression of microglial MMP-2 secretion by M.tb-infected monocyte-dependent networks paradoxically involves the pro-inflammatory mediators TNF-alpha, p38 MAP kinase and NFkappaB in addition to a novel caspase 8-dependent pathway. Terbium 59-61 mitogen-activated protein kinase 14 Homo sapiens 164-167 21569377-9 2011 In summary, suppression of microglial MMP-2 secretion by M.tb-infected monocyte-dependent networks paradoxically involves the pro-inflammatory mediators TNF-alpha, p38 MAP kinase and NFkappaB in addition to a novel caspase 8-dependent pathway. Terbium 59-61 nuclear factor kappa B subunit 1 Homo sapiens 183-191 21569377-9 2011 In summary, suppression of microglial MMP-2 secretion by M.tb-infected monocyte-dependent networks paradoxically involves the pro-inflammatory mediators TNF-alpha, p38 MAP kinase and NFkappaB in addition to a novel caspase 8-dependent pathway. Terbium 59-61 caspase 8 Homo sapiens 215-224 21595599-3 2011 The fact that TNF plays a role in the immune cell response and, more specifically, in maintenance of granuloma integrity is the accepted grounds for reactivation of TB following inhibition of TNF. Terbium 165-167 tumor necrosis factor Homo sapiens 192-195 21219931-10 2011 While in WT mice m-apoE is TBSX-soluble, in 5xFAD mice m-apoE is TBS- or GuHCl-soluble. Terbium 27-30 apolipoprotein E Mus musculus 19-23 21367459-7 2011 It is concluded that miR-144* might involve in regulation of anti-TB immunity through modification of cytokine production and cell proliferation of T cells. Terbium 66-68 microRNA 144 Homo sapiens 21-28 21459676-5 2011 A subgroup of 48 patients and 70 healthy controls was tested in parallel with T-SPOT.TB IP-10 and QFT-IT had comparable accuracy. Terbium 85-87 C-X-C motif chemokine ligand 10 Homo sapiens 88-93 21459676-10 2011 IFN-gamma but not IP-10 responses to mitogen stimulation were reduced in patients with TB and non-TB infection. Terbium 87-89 interferon gamma Homo sapiens 0-9 21459676-10 2011 IFN-gamma but not IP-10 responses to mitogen stimulation were reduced in patients with TB and non-TB infection. Terbium 98-100 interferon gamma Homo sapiens 0-9 21338678-3 2011 In a 14-month experiment, we showed that TB vaccine-induced CD4 T cell responses were heterogenous. Terbium 41-43 CD4 antigen Mus musculus 60-63 21471634-2 2011 These structures are compared to those of the spin liquid Tb(2)Ti(2)O(7) previously measured in similar experimental conditions. Terbium 58-60 spindlin 1 Homo sapiens 46-50 21796907-16 2011 The median CD4 count was very low in the TB/HIV co-infected individuals than those infected with TB alone. Terbium 41-43 CD4 molecule Homo sapiens 11-14 21385472-13 2011 Therefore, TB control programs in the Afar Region require the incorporation of public health education introducing current biomedical knowledge of the disease. Terbium 11-13 aldo-keto reductase family 7 member A2 Homo sapiens 38-42 21333105-6 2011 RESULTS: Before treatment, the plasma HNP1-3 concentration in the MDR-TB group was lower than that of healthy controls and the drug-susceptible group. Terbium 70-72 HNP1 Homo sapiens 38-42 20955826-5 2011 RESULTS: Carriers of the MTHFR 677 T-allele showed a lower baseline BMD(TB) than non-carriers (-0.38 SDS vs. +0.55 SDS, p = 0.01) and BMD(TB) remained lower during/after treatment. Terbium 72-74 methylenetetrahydrofolate reductase Homo sapiens 25-30 20955826-5 2011 RESULTS: Carriers of the MTHFR 677 T-allele showed a lower baseline BMD(TB) than non-carriers (-0.38 SDS vs. +0.55 SDS, p = 0.01) and BMD(TB) remained lower during/after treatment. Terbium 138-140 methylenetetrahydrofolate reductase Homo sapiens 25-30 21184031-12 2011 Phosphorylated eIF2alpha markedly decreased in TB-rats vs. C. Feeding the HMB-enriched diet resulted in decreased p-eIF2alpha levels in control animals, while no changes could be observed in the TB group. Terbium 47-49 eukaryotic translation initiation factor 2A Rattus norvegicus 15-24 21184031-13 2011 Phosphorylated p70S6K and phosphorylated mTOR were markedly increased by HMB treatment in controls and further increased in TB. Terbium 124-126 ribosomal protein S6 kinase B1 Rattus norvegicus 15-21 21184031-13 2011 Phosphorylated p70S6K and phosphorylated mTOR were markedly increased by HMB treatment in controls and further increased in TB. Terbium 124-126 mechanistic target of rapamycin kinase Rattus norvegicus 41-45 21333105-7 2011 After treatment, plasma HNP1-3 concentrations were higher than pre-treatment levels in the MDR-TB group, but were still lower than in healthy controls or the drug-susceptible group. Terbium 95-97 HNP1 Homo sapiens 24-28 22099930-16 2011 Although, nuclear beta-catenin accumulation at TBS was noted, yet, it did not relate significantly with both TB and cytoplasmic pseudofragments around TBS (p=.649; p=.675, respectively). Terbium 47-49 catenin beta 1 Homo sapiens 18-30 21069438-8 2011 High TBR (and TB) estimates of miR-21 expression correlated significantly with shorter disease-free survival (p = 0.004, HR = 1.28, 95% CI: 1.06-1.55) in the stage II colon cancer patient group, whereas no significant correlation with disease-free survival was observed in the stage II rectal cancer group. Terbium 5-7 microRNA 21 Homo sapiens 31-37 21219690-10 2011 We found positive correlations between both PCT and CRP and TB score. Terbium 60-62 C-reactive protein Homo sapiens 52-55 21706923-0 2011 Optimising pre-analytical performance of interferon-gamma release assays for TB exposure. Terbium 77-79 interferon gamma Homo sapiens 41-57 21876708-8 2011 Further, HLA-B*57 frequency in HIV cohort was significantly higher among females without TB (21.6%, 19/88) than males (1.7%, 1/59); P = 0.0046; OR = 38. Terbium 89-91 major histocompatibility complex, class I, B Homo sapiens 9-14 21876708-10 2011 CONCLUSION: This study suggests that HIV positive women with HLA-B*57 have less occurrence of TB as compared to males. Terbium 94-96 major histocompatibility complex, class I, B Homo sapiens 61-66 22455293-9 2010 CD4+ T cell percentage in newly diagnosed TB patients was 28.8 +/- 8.7 while it was 37.9 +/- 8.9 in TB patients who were on therapy and difference was statistically significant whereas difference in CD8+ T-cell percentages was statistically insignificant. Terbium 42-44 CD4 molecule Homo sapiens 0-3 21084459-8 2011 HLA-A*3001 and HLA-A*3002 major histocompatibility complex-peptide complexes were recognized in individuals with active TB, irrespective of their homozygous HLA-A*3001 or HLA-A*3002 genetic background. Terbium 120-122 major histocompatibility complex, class I, A Homo sapiens 0-5 21084459-8 2011 HLA-A*3001 and HLA-A*3002 major histocompatibility complex-peptide complexes were recognized in individuals with active TB, irrespective of their homozygous HLA-A*3001 or HLA-A*3002 genetic background. Terbium 120-122 major histocompatibility complex, class I, A Homo sapiens 15-20 21084459-8 2011 HLA-A*3001 and HLA-A*3002 major histocompatibility complex-peptide complexes were recognized in individuals with active TB, irrespective of their homozygous HLA-A*3001 or HLA-A*3002 genetic background. Terbium 120-122 major histocompatibility complex, class I, A Homo sapiens 15-20 21084459-8 2011 HLA-A*3001 and HLA-A*3002 major histocompatibility complex-peptide complexes were recognized in individuals with active TB, irrespective of their homozygous HLA-A*3001 or HLA-A*3002 genetic background. Terbium 120-122 major histocompatibility complex, class I, A Homo sapiens 15-20 21846947-6 2011 CONCLUSIONS: Our results provide evidence, for the first time, of a role for the TLR8 gene in susceptibility to pulmonary TB in male children. Terbium 122-124 toll like receptor 8 Homo sapiens 81-85 20722065-13 2011 Thus, current guidelines for TB screening prior anti-TNF-alpha therapy appear inaccurate in patients under IM. Terbium 29-31 tumor necrosis factor Homo sapiens 53-62 21276293-2 2011 METHOD: To assess the prevalence of TB in Viet Nam, a nationwide stratified cluster sample survey was conducted from 2006 to 2007. Terbium 36-38 SH3 and cysteine rich domain 3 Homo sapiens 47-50 21276293-8 2011 There was a significant association between TB prevalence rates and estimated household expenditure level, showing that TB is related to poverty in Viet Nam. Terbium 44-46 SH3 and cysteine rich domain 3 Homo sapiens 153-156 21269986-15 2011 CSF monitoring and careful inspection of the radiographic data can be helpful in the diagnosis of suspected cases, for which early anti-TB treatment is an important means to reduce misdiagnosis. Terbium 136-138 colony stimulating factor 2 Homo sapiens 0-3 20881436-3 2011 OBJECTIVE: To determine whether lower Alb occurring in newborns undergoing abdominal surgery shortly after birth results in significantly higher UB in serum versus nonsurgical patients at comparable serum TB. Terbium 205-207 albumin Homo sapiens 38-41 21344150-2 2011 Significantly higher IFN-? responses to TB-specific antigens were associated with younger age, but no difference was found with Mitogen responses. Terbium 40-42 interferon alpha 1 Homo sapiens 21-26 21754976-1 2011 It is well-established that tumour necrosis factor (TNF)-alpha-antagonist regimens are advisable for the control of moderate to severe psoriasis; however the application of these agents is associated with increased risk of TB reactivation. Terbium 223-225 tumor necrosis factor Homo sapiens 28-62 22132131-7 2011 TB mice showed a significant increase in serum levels of pro-inflammatory factors IL-6 and MCP-1 measured by CBA. Terbium 0-2 interleukin 6 Mus musculus 82-86 22132131-7 2011 TB mice showed a significant increase in serum levels of pro-inflammatory factors IL-6 and MCP-1 measured by CBA. Terbium 0-2 chemokine (C-C motif) ligand 2 Mus musculus 91-96 21931674-2 2011 India, however, still limits ART to those TB patients with CD4 counts <350/mm(3) or with extrapulmonary TB manifestations. Terbium 42-44 CD4 molecule Homo sapiens 59-62 22355539-4 2011 We found that rs2227473, an SNP in the promoter region of IL-22, is associated with TB susceptibility at both stages of our study. Terbium 84-86 interleukin 22 Homo sapiens 58-63 20977362-4 2010 RESULTS: When compared with control participants, levels of IL-18 and CXCL10 were higher in TB-IRIS case patients (P = .002 and .006, respectively), whereas CCL2 was lower (P = .006). Terbium 92-94 interleukin 18 Homo sapiens 60-65 20977362-4 2010 RESULTS: When compared with control participants, levels of IL-18 and CXCL10 were higher in TB-IRIS case patients (P = .002 and .006, respectively), whereas CCL2 was lower (P = .006). Terbium 92-94 C-X-C motif chemokine ligand 10 Homo sapiens 70-76 20977362-6 2010 When TB-IRIS case patients were compared with ART-TB case patients, IL-18 was higher in ART-TB (P = .03), whereas CXCL10 was higher in TB-IRIS (P = .001). Terbium 5-7 interleukin 18 Homo sapiens 68-73 20977362-6 2010 When TB-IRIS case patients were compared with ART-TB case patients, IL-18 was higher in ART-TB (P = .03), whereas CXCL10 was higher in TB-IRIS (P = .001). Terbium 5-7 C-X-C motif chemokine ligand 10 Homo sapiens 114-120 20977362-6 2010 When TB-IRIS case patients were compared with ART-TB case patients, IL-18 was higher in ART-TB (P = .03), whereas CXCL10 was higher in TB-IRIS (P = .001). Terbium 50-52 interleukin 18 Homo sapiens 68-73 20599324-11 2010 The activity of TB-2-081 implicates an important role for IL-6 in sustaining pancreatitis pain. Terbium 16-18 interleukin 6 Rattus norvegicus 58-62 21045406-0 2010 CD4 cell count recovery in HIV/TB co-infected patients versus TB uninfected HIV patients. Terbium 31-33 CD4 molecule Homo sapiens 0-3 21045406-2 2010 We sought to test the hypothesis; TB additionally contributes to reduction in CD4 count in HIV/TB co-infected patients and this would result in greater improvement in count following treatment compared with CD4 matched TB uninfected individuals. Terbium 34-36 CD4 molecule Homo sapiens 78-81 21045406-9 2010 CONCLUSION: Greater increment in CD4 counts with ATT and ART in dually infected patients suggests that TB additionally influences the reduction of CD4 counts in HIV patients. Terbium 103-105 CD4 molecule Homo sapiens 33-36 21045406-9 2010 CONCLUSION: Greater increment in CD4 counts with ATT and ART in dually infected patients suggests that TB additionally influences the reduction of CD4 counts in HIV patients. Terbium 103-105 CD4 molecule Homo sapiens 147-150 21991356-8 2011 Our results also suggest a role for CCL-2 in maintaining the integrity of granuloma in asymptomatic individuals with latent infection in high TB burden settings. Terbium 142-144 C-C motif chemokine ligand 2 Homo sapiens 36-41 21738575-11 2011 CONCLUSIONS: The Xpert MTB/RIF Assay is a highly sensitive, specific and rapid method for diagnosing TB which has potential to complement the current reference standard of TB diagnostics and increase its overall sensitivity. Terbium 101-103 ras homolog family member F, filopodia associated Homo sapiens 27-30 21143955-14 2010 On the contrary, percentages of positive results in patients with CD4> 200 were 10.9% (6/55), 9.1% (5/55) and 16.4% (9/55) with T-SPOT.TB, QFN-G-IT and TST, respectively. Terbium 138-140 thiosulfate sulfurtransferase Homo sapiens 155-158 21126375-10 2010 Two commercial interferon-gamma release assays, QFT-G-IT and T-SPOT.TB have been developed. Terbium 68-70 interferon gamma Homo sapiens 15-31 20833102-8 2010 Anti-TB activity of the ligand has enhanced on complexation with Co(II) and Ni(II) ions. Terbium 5-7 mitochondrially encoded cytochrome c oxidase II Homo sapiens 65-71 20883321-4 2010 IFN-gamma +874 genotype AA was significantly higher in patients with TB than that in control (Pc=0.015), in extrapulmonary than patients with pulmonary TB (PTB) (Pc=0.009), and young children with TB below 5 years (Pc=0.024). Terbium 152-154 interferon gamma Homo sapiens 0-9 20797557-10 2010 All cell counts and CD4/CD8 were found to be higher in TST-positive patients, whereas only total lymphocytes count and CD4/CD8 were reported to be high in IFN-TB-positive patients. Terbium 159-161 CD8a molecule Homo sapiens 123-126 20596557-1 2010 Construction of a 3-D supramolecular network from [Ln(cpb)(3)(H(2)O)(2)] (Ln = Nd, Tb; Hcpb = 1-(4-cyanophenyl)-1,3-butanedione) by sequential displacement of a coordinated water by DMF, dimerisation by reciprocal hydrogen bonding in solution and pi-pi stacking and interdigitation of nitriles has been monitored by in situ fourier transform infrared spectroscopy. Terbium 83-85 carboxypeptidase B1 Homo sapiens 54-57 20716363-9 2010 Additionally, the NF-kappaB inhibitors significantly inhibited the experimental lung metastasis of Tb cells and lymph node metastasis of TL cells in nude mice. Terbium 99-101 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 18-27 19615018-11 2010 Staining for CK17 was always positive in TB. Terbium 41-43 keratin 17 Homo sapiens 13-17 20883321-4 2010 IFN-gamma +874 genotype AA was significantly higher in patients with TB than that in control (Pc=0.015), in extrapulmonary than patients with pulmonary TB (PTB) (Pc=0.009), and young children with TB below 5 years (Pc=0.024). Terbium 69-71 interferon gamma Homo sapiens 0-9 20883321-4 2010 IFN-gamma +874 genotype AA was significantly higher in patients with TB than that in control (Pc=0.015), in extrapulmonary than patients with pulmonary TB (PTB) (Pc=0.009), and young children with TB below 5 years (Pc=0.024). Terbium 152-154 interferon gamma Homo sapiens 0-9 20977840-9 2010 Serum VEGF levels (ng/L) were significantly lower before treatment in control group, TB group and UB group than those in normal control group (79.87+-2.81, 80.19+-3.23, 80.23+-3.18 vs. 68.13+-3.39, all P<0.05). Terbium 85-87 vascular endothelial growth factor A Homo sapiens 6-10 20797905-9 2010 The present study suggests that T allele of TIRAP 975C/T polymorphism may be associated with susceptibility to pulmonary TB in south Indian population. Terbium 121-123 TIR domain containing adaptor protein Homo sapiens 44-49 20824205-8 2010 Early TB lesions were characterized by a highly pro-inflammatory environment, expressing high levels of immune signaling pathways involving IFNgamma, TNFalpha, JAK, STAT and C-C/C-X-C chemokines. Terbium 6-8 interferon gamma Homo sapiens 140-148 20824205-8 2010 Early TB lesions were characterized by a highly pro-inflammatory environment, expressing high levels of immune signaling pathways involving IFNgamma, TNFalpha, JAK, STAT and C-C/C-X-C chemokines. Terbium 6-8 tumor necrosis factor Homo sapiens 150-158 20646207-5 2010 In order to identify the usefulness of TNF in improving the effectiveness of TB vaccine, in the current study a novel rBCG strain expressing the fusion gene of Ag85B-Esat6-TNF-alpha in BCG Danish strain was constructed, and its ability to induce an immune response in C57BL/6 mice evaluated. Terbium 77-79 tumor necrosis factor Mus musculus 39-42 21399250-4 2010 Tb(3+)-doped LPS yields both the blue emission [Formula: see text] (J = 3, 4, 5, 6) and the green emission [Formula: see text] (J = 3, 4, 5, 6) of Tb(3+). Terbium 0-2 interferon regulatory factor 6 Homo sapiens 13-16 19697148-4 2010 Thus, M. tb DHFR (mtDHFR) is an attractive novel drug target for developing anti-TB drugs. Terbium 81-83 dihydrofolate reductase Homo sapiens 12-16 21399250-7 2010 Two different crystallographic sites of Tb(3+) in the LPS lattice were detected in the luminescence and excitation spectra of samples with higher Tb(3+) concentrations (6-9 mol%). Terbium 40-42 interferon regulatory factor 6 Homo sapiens 54-57 21399250-9 2010 Calculation of colour coordinates shows that LPS:Ce(0.25%)Tb(3%) emits white light. Terbium 58-60 interferon regulatory factor 6 Homo sapiens 45-48 20662245-9 2010 Therefore, famous researchers in the fields of TB immunity reviewed the recent advances of TB immunity, such as (1) T cell immunity and recognition against TB antigen, (2) TLR9 and CpG motif, (3) lipocalin2 and SLPI in natural TB immunity, (4) acquired immunity (CTL) and granulysin. Terbium 91-93 toll-like receptor 9 Mus musculus 172-176 20637972-15 2010 TB-402 was associated with a reduction in FVIII:C over a period of approximately 48 hours in the d37.5-microg/kg dose groups. Terbium 0-3 coagulation factor VIII Homo sapiens 42-47 20669606-2 2010 Following an outbreak of TB in 2 creches in the HSE South, a universal BCG vaccination program was re-introduced in October 2008. Terbium 25-27 hydroxysteroid 17-beta dehydrogenase 6 Homo sapiens 48-51 20371596-4 2010 The chemokine CCL5 has been detected in patients with TB and implicated in control of M.tb infection. Terbium 54-56 C-C motif chemokine ligand 5 Homo sapiens 14-18 20371596-4 2010 The chemokine CCL5 has been detected in patients with TB and implicated in control of M.tb infection. Terbium 88-90 C-C motif chemokine ligand 5 Homo sapiens 14-18 20371596-8 2010 Lung cells from M.tb-infected CCL5 KO mice eventually reached or exceeded the levels of WT mice, likely as a result of partial compensation by the CCL5-related ligand, CCL4, and not because of CCL3. Terbium 18-20 chemokine (C-C motif) ligand 5 Mus musculus 30-34 20371596-8 2010 Lung cells from M.tb-infected CCL5 KO mice eventually reached or exceeded the levels of WT mice, likely as a result of partial compensation by the CCL5-related ligand, CCL4, and not because of CCL3. Terbium 18-20 chemokine (C-C motif) ligand 5 Mus musculus 147-151 20371596-8 2010 Lung cells from M.tb-infected CCL5 KO mice eventually reached or exceeded the levels of WT mice, likely as a result of partial compensation by the CCL5-related ligand, CCL4, and not because of CCL3. Terbium 18-20 chemokine (C-C motif) ligand 4 Mus musculus 168-172 20662245-9 2010 Therefore, famous researchers in the fields of TB immunity reviewed the recent advances of TB immunity, such as (1) T cell immunity and recognition against TB antigen, (2) TLR9 and CpG motif, (3) lipocalin2 and SLPI in natural TB immunity, (4) acquired immunity (CTL) and granulysin. Terbium 47-49 toll-like receptor 9 Mus musculus 172-176 20662245-9 2010 Therefore, famous researchers in the fields of TB immunity reviewed the recent advances of TB immunity, such as (1) T cell immunity and recognition against TB antigen, (2) TLR9 and CpG motif, (3) lipocalin2 and SLPI in natural TB immunity, (4) acquired immunity (CTL) and granulysin. Terbium 47-49 lipocalin 2 Mus musculus 196-206 20662245-9 2010 Therefore, famous researchers in the fields of TB immunity reviewed the recent advances of TB immunity, such as (1) T cell immunity and recognition against TB antigen, (2) TLR9 and CpG motif, (3) lipocalin2 and SLPI in natural TB immunity, (4) acquired immunity (CTL) and granulysin. Terbium 47-49 secretory leukocyte peptidase inhibitor Mus musculus 211-215 20188863-5 2010 LTA(+368) and IL10(-592) were associated with different clinical forms of TB (P<0.05). Terbium 74-76 interleukin 10 Homo sapiens 14-18 20188863-8 2010 Carriers of IL10(-592)*C were under-represented among those with pulmonary TB and all TB forms (P<0.001). Terbium 75-77 interleukin 10 Homo sapiens 12-16 20188863-9 2010 IL10(-1082)-IL10(-592) haplotypes showed different distributions among patients with pulmonary TB and all TB forms (P<0.01) when compared to healthy controls. Terbium 95-97 interleukin 10 Homo sapiens 0-4 20188863-9 2010 IL10(-1082)-IL10(-592) haplotypes showed different distributions among patients with pulmonary TB and all TB forms (P<0.01) when compared to healthy controls. Terbium 95-97 interleukin 10 Homo sapiens 12-16 20188863-12 2010 These results suggest that the polymorphisms LTA(+368) and IL10(-592), or variants in strong linkage disequilibrium, variably affect susceptibility to the differing clinical forms of TB in Peruvians. Terbium 183-185 interleukin 10 Homo sapiens 59-63 21125170-4 2010 Due to the risk of activating latent tuberculosis with the administration of anti-TNFalpha and hepatotoxicity onset caused by the TB treatment and based on the fact that the treatment of PA is similar to the treatment of rheumatoid arthritis, a decision was made to use the empirical treatment with abatacept. Terbium 130-132 tumor necrosis factor Homo sapiens 82-90 20406980-7 2010 Knockdown of MMP13 expression at the TB interface leads to significant reduction in bone destruction and in the number of activated osteoclasts at the TB interface. Terbium 37-39 matrix metallopeptidase 13 Mus musculus 13-18 20406980-7 2010 Knockdown of MMP13 expression at the TB interface leads to significant reduction in bone destruction and in the number of activated osteoclasts at the TB interface. Terbium 151-153 matrix metallopeptidase 13 Mus musculus 13-18 20406980-9 2010 Together, our data indicate that upregulation of MMP13 at the TB interface is important in tumor-induced osteolysis and suggest that MMP13 is a potential therapeutic target for breast cancer bone metastasis. Terbium 62-64 matrix metallopeptidase 13 Mus musculus 49-54 20442134-0 2010 Questions About Adenosine Deaminase Testing and Drug Choice in an Unusual Presentation of TB. Terbium 90-92 adenosine deaminase Homo sapiens 16-35 20229057-10 2010 CONCLUSION: Supplementing IL-15 + IL-12 in vitro increased the number of NK cells that are expressing cytolytic molecules in HIV-infected individuals but in HIV-TB, the critical cytolytic molecule, perforin is not apparent perhaps due to the influence of TB on HIV. Terbium 161-163 interleukin 15 Homo sapiens 26-31 20196153-4 2010 The poly(arginine)-tagged albumin precipitated selectively and quantitatively, so that the apoferritin-Tb(3+) complex can function as a new luminescent biotool for the sensing of poly(arginine) and its protein conjugates. Terbium 103-105 ferritin heavy chain 1 Homo sapiens 91-102 20662245-9 2010 Therefore, famous researchers in the fields of TB immunity reviewed the recent advances of TB immunity, such as (1) T cell immunity and recognition against TB antigen, (2) TLR9 and CpG motif, (3) lipocalin2 and SLPI in natural TB immunity, (4) acquired immunity (CTL) and granulysin. Terbium 91-93 lipocalin 2 Mus musculus 196-206 20662245-9 2010 Therefore, famous researchers in the fields of TB immunity reviewed the recent advances of TB immunity, such as (1) T cell immunity and recognition against TB antigen, (2) TLR9 and CpG motif, (3) lipocalin2 and SLPI in natural TB immunity, (4) acquired immunity (CTL) and granulysin. Terbium 91-93 secretory leukocyte peptidase inhibitor Mus musculus 211-215 20662245-9 2010 Therefore, famous researchers in the fields of TB immunity reviewed the recent advances of TB immunity, such as (1) T cell immunity and recognition against TB antigen, (2) TLR9 and CpG motif, (3) lipocalin2 and SLPI in natural TB immunity, (4) acquired immunity (CTL) and granulysin. Terbium 91-93 toll-like receptor 9 Mus musculus 172-176 20662245-9 2010 Therefore, famous researchers in the fields of TB immunity reviewed the recent advances of TB immunity, such as (1) T cell immunity and recognition against TB antigen, (2) TLR9 and CpG motif, (3) lipocalin2 and SLPI in natural TB immunity, (4) acquired immunity (CTL) and granulysin. Terbium 91-93 lipocalin 2 Mus musculus 196-206 20662245-9 2010 Therefore, famous researchers in the fields of TB immunity reviewed the recent advances of TB immunity, such as (1) T cell immunity and recognition against TB antigen, (2) TLR9 and CpG motif, (3) lipocalin2 and SLPI in natural TB immunity, (4) acquired immunity (CTL) and granulysin. Terbium 91-93 secretory leukocyte peptidase inhibitor Mus musculus 211-215 20388213-0 2010 Mycobacterium tuberculosis Rv0679c protein sequences involved in host-cell infection: potential TB vaccine candidate antigen. Terbium 96-98 hypothetical protein Mycobacterium tuberculosis H37Rv 27-34 20662245-9 2010 Therefore, famous researchers in the fields of TB immunity reviewed the recent advances of TB immunity, such as (1) T cell immunity and recognition against TB antigen, (2) TLR9 and CpG motif, (3) lipocalin2 and SLPI in natural TB immunity, (4) acquired immunity (CTL) and granulysin. Terbium 91-93 toll-like receptor 9 Mus musculus 172-176 20662245-9 2010 Therefore, famous researchers in the fields of TB immunity reviewed the recent advances of TB immunity, such as (1) T cell immunity and recognition against TB antigen, (2) TLR9 and CpG motif, (3) lipocalin2 and SLPI in natural TB immunity, (4) acquired immunity (CTL) and granulysin. Terbium 91-93 lipocalin 2 Mus musculus 196-206 20662245-9 2010 Therefore, famous researchers in the fields of TB immunity reviewed the recent advances of TB immunity, such as (1) T cell immunity and recognition against TB antigen, (2) TLR9 and CpG motif, (3) lipocalin2 and SLPI in natural TB immunity, (4) acquired immunity (CTL) and granulysin. Terbium 91-93 secretory leukocyte peptidase inhibitor Mus musculus 211-215 20078125-5 2010 Additionally, BET experiments were performed to determine the influence of three-hydride formation on the area of a thin Tb film. Terbium 121-123 delta/notch like EGF repeat containing Homo sapiens 14-17 19898919-3 2010 MTB antigen (ESAT-6 and CFP-10)-induced IFN-gamma-releasing assay was performed with or without addition of biologics (TCZ, ETA, and INF) using whole blood from patients with active TB. Terbium 1-3 interferon gamma Homo sapiens 40-49 20087697-4 2010 The changes in the microstructure of Tween 80-based microemulsion in the presence of anti-TB drugs have been established using conductivty (sigma) and viscosity (eta) behavior. Terbium 90-92 endothelin receptor type A Homo sapiens 162-165 20450681-8 2010 The migration of highly metastatic Tb cells, either transfected with dominant-negative mutant inhibitor pBalphabe-SR-IkappaBalpha or treated with PDTC, was suppressed when determined by transwell assay. Terbium 35-37 NFKB inhibitor alpha Homo sapiens 117-129 20371919-9 2010 CONCLUSION: Considering the function of CD56/CD16 expressing cells in TB, we suggest that phenotypic characteristics of PBMCs in MDR-TB may correlate with their status of drug resistance and probably with their high mortality rates. Terbium 70-72 neural cell adhesion molecule 1 Homo sapiens 40-44 20371919-9 2010 CONCLUSION: Considering the function of CD56/CD16 expressing cells in TB, we suggest that phenotypic characteristics of PBMCs in MDR-TB may correlate with their status of drug resistance and probably with their high mortality rates. Terbium 70-72 Fc gamma receptor IIIa Homo sapiens 45-49 20083961-7 2010 At baseline, CRP was positively correlated with IL-6 (r = 0.35), (TB-FM) (r = 0.36), and IA-FM (r = 0.31) and was inversely correlated with aerobic fitness measures (all r values > or = -0.24). Terbium 66-68 C-reactive protein Homo sapiens 13-16 20146818-8 2010 TB prevalence was 25.3%, associated with lower CD4 (AHR 2.61 p = 0.01 for CD4 <50 cells/microl) and prior TB (AHR 1.58 p = 0.02). Terbium 0-2 CD4 molecule Homo sapiens 47-50 20146818-8 2010 TB prevalence was 25.3%, associated with lower CD4 (AHR 2.61 p = 0.01 for CD4 <50 cells/microl) and prior TB (AHR 1.58 p = 0.02). Terbium 0-2 CD4 molecule Homo sapiens 74-77 19891553-9 2009 CONCLUSION: These findings suggest that genetic variants in the promoter and exons of NAT2 increase the risk of anti-TB drug-induced hepatitis by modifying acetylation phenotypes and/or gene expression of NAT2, and there is no essential role for genetic mutation of the other metabolizing enzymes in the development of this adverse reaction. Terbium 117-119 N-acetyltransferase 2 Homo sapiens 86-90 20113509-1 2010 BACKGROUND: To investigate whether the toll-like receptor 2 polymorphisms could influence susceptibility to pulmonary TB, its phenotypes, and blood lymphocyte subsets. Terbium 118-120 toll like receptor 2 Homo sapiens 39-59 20113509-10 2010 CONCLUSIONS: TLR2 genetic polymorphisms influence susceptibility to pulmonary TB. Terbium 78-80 toll like receptor 2 Homo sapiens 13-17 20113509-11 2010 TLR2 variants play a role in the development of TB phenotypes, probably by controlling the expansion of NK cells. Terbium 48-50 toll like receptor 2 Homo sapiens 0-4 19948042-0 2009 Evaluation of the tuberculin skin test and the interferon-gamma release assay for TB screening in French healthcare workers. Terbium 82-84 interferon gamma Homo sapiens 47-63 19603199-6 2009 The kinetic synchronization of internalization of both Tb and Tf into human leukemia K562 cells demonstrated the Tb(2)Tf complex was transported into cells as a whole. Terbium 55-57 transferrin Homo sapiens 118-120 19898919-1 2010 Interferon gamma (IFN-gamma) production is a critical step of antituberculosis (anti-TB) immune response. Terbium 85-87 interferon gamma Homo sapiens 0-27 20530906-3 2010 Purification was performed by a combination of immobilized metal-ion affinity chromatography (IMAC) and size exclusion chromatography (SEC), yielding 176 mg of PPAR-gamma of over 90% purity per liter of TB. Terbium 203-205 peroxisome proliferator activated receptor gamma Homo sapiens 160-170 19472023-8 2009 We found higher matrix concentrations of TGF-beta2 were associated with higher Tb.Sp and VMExp/sigma(app) for pooled data and within subjects. Terbium 79-81 transforming growth factor beta 2 Homo sapiens 41-50 19472023-9 2009 Similarly, a higher matrix concentration of IGF-I was associated with lower stiffness, strength, BV/TV and Tb.Th and with higher BS/BV, Tb.Sp, VMExp/sigma(app) and VMCOV for pooled data and within subjects. Terbium 107-109 insulin like growth factor 1 Homo sapiens 44-49 19891553-9 2009 CONCLUSION: These findings suggest that genetic variants in the promoter and exons of NAT2 increase the risk of anti-TB drug-induced hepatitis by modifying acetylation phenotypes and/or gene expression of NAT2, and there is no essential role for genetic mutation of the other metabolizing enzymes in the development of this adverse reaction. Terbium 117-119 N-acetyltransferase 2 Homo sapiens 205-209 19803716-6 2009 The results suggest that HLA-A*1101 may be associated with protection against HIV and the development of TB in HIV patients while HLA-B*4006 may be associated with susceptibility to HIV and TB development in HIV patients. Terbium 105-107 major histocompatibility complex, class I, A Homo sapiens 25-30 19780967-0 2009 A novel DNA vaccine containing multiple TB-specific epitopes cast in a natural structure elicits enhanced Th1 immunity compared with BCG. Terbium 40-42 negative elongation factor complex member C/D, Th1l Mus musculus 106-109 19838090-0 2009 [Use of PCR for TB bacteria on BAL in early diagnosis of tubercular lobitis]. Terbium 16-18 poly(ADP-ribose) polymerase family member 9 Homo sapiens 31-34 19551847-10 2009 RESULTS: IHC for ER on alcohol-fixed CB samples had good correlation with NC and TB samples. Terbium 81-83 estrogen receptor 1 Homo sapiens 17-19 19447677-7 2009 Further, T-cell responses to RD1 peptides were lower in the 23 active-TB treated patients than in the untreated ones (p<0.01). Terbium 70-72 phosphodiesterase 6B Homo sapiens 29-32 19445695-8 2009 Combinations between EGF, sCD40L, VEGF, TGF-alpha and IL-1alpha also showed potential to differentiate between TB infection states. Terbium 111-113 interleukin 1 alpha Homo sapiens 54-63 19432995-4 2009 The number of T-SPOT.TB positives represents 11% of the individuals defined as recently infected by TST after exposure (3/27) and 2% of the total number of exposed people tested (3/155). Terbium 21-23 thiosulfate sulfurtransferase Homo sapiens 100-103 19432995-5 2009 In addition, 15 individuals had been previously defined as infected by TST before exposure of whom 2 subjects were T-SPOT.TB positive. Terbium 122-124 thiosulfate sulfurtransferase Homo sapiens 71-74 19432995-6 2009 All individuals detected as T-SPOT.TB positive belonged to the TST positive group (> 15 mm), and the percentage concordance between T-SPOT.TB and TST, including both previously and newly infected subjects, was 12% (5/42). Terbium 35-37 thiosulfate sulfurtransferase Homo sapiens 63-66 19529765-4 2009 CD4/10.4 and CD8/10.4 T cells displayed marked differences in terms of expansion and contraction in a mouse TB model. Terbium 108-110 CD4 antigen Mus musculus 0-3 19618035-10 2009 CONCLUSIONS: Pleural TB was the predominant extrapulmonary form of TB in the state of Sao Paulo, with a stable incidence between 1998 and 2005, although there was a trend toward a decrease in the incidence of the pulmonary forms. Terbium 21-23 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 86-89 19618035-10 2009 CONCLUSIONS: Pleural TB was the predominant extrapulmonary form of TB in the state of Sao Paulo, with a stable incidence between 1998 and 2005, although there was a trend toward a decrease in the incidence of the pulmonary forms. Terbium 67-69 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 86-89 18418730-8 2009 TGF-beta1 did not increase p27 expression in Tca8113 cells, but p27 expression was increased in Tb cells. Terbium 96-98 zinc ribbon domain containing 2 Homo sapiens 64-67 19386033-4 2009 Studies examining the association between genetic polymorphisms, particularly the gene coding for the vitamin D receptor (VDR), and TB susceptibility and treatment response are inconclusive. Terbium 132-134 vitamin D receptor Homo sapiens 102-120 19386033-4 2009 Studies examining the association between genetic polymorphisms, particularly the gene coding for the vitamin D receptor (VDR), and TB susceptibility and treatment response are inconclusive. Terbium 132-134 vitamin D receptor Homo sapiens 122-125 19224035-10 2009 The large difference in eta(sens) for microcrystalline samples of Eu (85%) and Tb (42%) tris(dipicolinates) is attributed to back energy transfer in the latter compound consecutive to a sizeable overlap between the (5)D(4)-->(7)F(6) emission and the absorption spectrum of the dipicolinate triplet, this overlap being smaller in the case of the solution. Terbium 79-81 endothelin receptor type A Homo sapiens 24-27 19228353-10 2009 CONCLUSION: The change in risk of a TB cluster was linked to socio-economic (e.g. household amount of ownership of tap water) and patient care factors (e.g. patients lost to follow-up). Terbium 36-38 nuclear RNA export factor 1 Homo sapiens 115-118 19250549-9 2009 CONCLUSION: IFN-gamma-producing RD1-specific T cells, as measured in the T-SPOT.TB assay, may be directly related to bacterial load in patients undergoing treatment for pulmonary TB. Terbium 80-82 interferon gamma Homo sapiens 12-21 19147409-2 2009 Polymorphisms in two of these genes, namely NOS2A and CCL2, have been associated with TB in various populations. Terbium 86-88 nitric oxide synthase 2 Homo sapiens 44-49 19147409-2 2009 Polymorphisms in two of these genes, namely NOS2A and CCL2, have been associated with TB in various populations. Terbium 86-88 C-C motif chemokine ligand 2 Homo sapiens 54-58 19147409-3 2009 To investigate a possible association of gene variants with TB in the South African Coloured population we genotyped SNPs from NOS2A and CCL2 in over 800 TB cases and controls. Terbium 154-156 C-C motif chemokine ligand 2 Homo sapiens 137-141 19147409-4 2009 We found a significant association between TB and two haplotypes, containing the functional rs9282799 and rs8078340 SNPs, in the NOS2A promoter. Terbium 43-45 nitric oxide synthase 2 Homo sapiens 129-134 19147409-7 2009 In the single-point analysis of NOS2A, rs2779249 (previously associated with TB in Brazilians) and the functional rs8078340 were nominally associated with disease. Terbium 77-79 nitric oxide synthase 2 Homo sapiens 32-37 19147409-9 2009 This study presents evidence that haplotypes in the NOS2A promoter influence susceptibility to TB and confirms the importance of NO production in the disease. Terbium 95-97 nitric oxide synthase 2 Homo sapiens 52-57 19250549-9 2009 CONCLUSION: IFN-gamma-producing RD1-specific T cells, as measured in the T-SPOT.TB assay, may be directly related to bacterial load in patients undergoing treatment for pulmonary TB. Terbium 80-82 phosphodiesterase 6B Homo sapiens 32-35 18706526-2 2008 Patients with immune-mediated inflammatory diseases (IMID) and suspected LTBI who are candidates for anti-TNF therapy are at a significant risk of TB reactivation yet are prone to false-negative TST results because they are already on immunosuppressive medications. Terbium 74-76 tumor necrosis factor Homo sapiens 106-109 18803615-8 2009 RESULTS: Compared with the pre-dialysis level, there was an obvious reduction in the IFN-gamma production level (in response to the TB-antigen cocktails) after the HD process (P=0.00). Terbium 132-134 interferon gamma Homo sapiens 85-94 19038005-5 2009 Moreover, TGF-betaRI expression and activation, analyzed by nuclear localization of phospho-Smad2, was higher in tumor cells and osteoclasts at the TB interface as compared to the tumor-alone area. Terbium 148-150 transforming growth factor beta receptor 1 Homo sapiens 10-20 19038005-8 2009 Together, these studies demonstrate that inhibition of TGF-betaRI signaling at the TB interface will be a therapeutic target in the treatment of breast cancer-induced osteolysis. Terbium 83-85 transforming growth factor beta receptor 1 Homo sapiens 55-65 19340290-12 2009 A positive correlation between ESAT6-induced IFNgamma and CXCL9 was present in all TB patients, but IFNgamma and CCL2 was only correlated in LNTB. Terbium 83-85 interferon gamma Homo sapiens 45-53 19340290-12 2009 A positive correlation between ESAT6-induced IFNgamma and CXCL9 was present in all TB patients, but IFNgamma and CCL2 was only correlated in LNTB. Terbium 83-85 C-X-C motif chemokine ligand 9 Homo sapiens 58-63 19125189-9 2009 CONCLUSIONS/ SIGNIFICANCE: By following quantitative IFNgamma values in each enrolled child with LTBI or active TB and receiving treatment, we were able to detect an increase in the IFNgamma response at day 10 of treatment which might allow the confirmation of a diagnosis. Terbium 98-100 interferon gamma Homo sapiens 53-61 19125189-9 2009 CONCLUSIONS/ SIGNIFICANCE: By following quantitative IFNgamma values in each enrolled child with LTBI or active TB and receiving treatment, we were able to detect an increase in the IFNgamma response at day 10 of treatment which might allow the confirmation of a diagnosis. Terbium 98-100 interferon gamma Homo sapiens 182-190 19237023-5 2009 CD11c levels decreased in response to anti-TB treatment. Terbium 43-45 integrin subunit alpha X Homo sapiens 0-5 19182419-4 2009 In an analogous way, the competitive relations were observed between EGCG and the site-I- (PB and TB) and site-II-binding (ethacrynic acid, EA) drugs for the binding of EGCG and BSA. Terbium 98-100 albumin Homo sapiens 178-181 19379168-4 2009 The TBS should have a high affinity for beta(2)-m so that the conjugates bind with the beta(2)-m in the bloodstream. Terbium 4-7 beta-2-microglobulin Homo sapiens 40-49 19379168-4 2009 The TBS should have a high affinity for beta(2)-m so that the conjugates bind with the beta(2)-m in the bloodstream. Terbium 4-7 beta-2-microglobulin Homo sapiens 87-96 19146687-11 2009 Finally, both methods agreed well with the TST, k = 0.86 for TST/QuantiFERON-TB Gold and k = 0.76 for TST/T SPOT-TB. Terbium 77-79 thiosulfate sulfurtransferase Homo sapiens 43-46 19590968-3 2009 However, the regulation and functional significance of RANKL at the TB-interface in tumor-induced osteolysis remains unclear. Terbium 68-70 TNF superfamily member 11 Homo sapiens 55-60 19590968-5 2009 Using a novel mammary tumor model, we identified that RANKL expression was upregulated at the TB-interface as compared to the tumor alone area. Terbium 94-96 TNF superfamily member 11 Homo sapiens 54-59 19590968-7 2009 The ratio of RANKL to osteoprotegrin (OPG), a decoy receptor for RANKL, at the TB-interface was also increased. Terbium 79-81 TNF superfamily member 11 Homo sapiens 13-18 19590968-7 2009 The ratio of RANKL to osteoprotegrin (OPG), a decoy receptor for RANKL, at the TB-interface was also increased. Terbium 79-81 TNF superfamily member 11 Homo sapiens 65-70 19590968-8 2009 Targeting RANKL expression with antisense oligonucleotides (RANKL-ASO), significantly abrogated tumor-induced osteolysis, decreased RANKL expression and the RANKL:OPG ratio at the TB-interface. Terbium 180-182 TNF superfamily member 11 Homo sapiens 10-15 19590968-8 2009 Targeting RANKL expression with antisense oligonucleotides (RANKL-ASO), significantly abrogated tumor-induced osteolysis, decreased RANKL expression and the RANKL:OPG ratio at the TB-interface. Terbium 180-182 TNF superfamily member 11 Homo sapiens 60-65 19590968-8 2009 Targeting RANKL expression with antisense oligonucleotides (RANKL-ASO), significantly abrogated tumor-induced osteolysis, decreased RANKL expression and the RANKL:OPG ratio at the TB-interface. Terbium 180-182 TNF superfamily member 11 Homo sapiens 60-65 19590968-8 2009 Targeting RANKL expression with antisense oligonucleotides (RANKL-ASO), significantly abrogated tumor-induced osteolysis, decreased RANKL expression and the RANKL:OPG ratio at the TB-interface. Terbium 180-182 TNF superfamily member 11 Homo sapiens 60-65 19590968-9 2009 Together, these results demonstrate that upregulation of RANKL expression and sRANKL generation at the TB-interface potentiates tumor-induced osteolysis. Terbium 103-105 TNF superfamily member 11 Homo sapiens 57-62 19277111-9 2009 IP-10 levels were significantly higher in TB vs non-TB participants (p<0.0001). Terbium 42-44 C-X-C motif chemokine ligand 10 Homo sapiens 0-5 19277111-9 2009 IP-10 levels were significantly higher in TB vs non-TB participants (p<0.0001). Terbium 52-54 C-X-C motif chemokine ligand 10 Homo sapiens 0-5 19277111-11 2009 Thus IP-10, using the ROC-derived cut-point, missed approximately 20% of TB cases and mis-diagnosed approximately 20% of non-TB cases. Terbium 73-75 C-X-C motif chemokine ligand 10 Homo sapiens 5-10 18972258-9 2009 Baseline osteocalcin and CTX-1 were independently associated with bone loss in TB and TF, respectively. Terbium 79-81 bone gamma-carboxyglutamate protein Homo sapiens 9-20 18706526-9 2008 Given the clinical imperative to prevent reactivation of TB in patients starting anti-TNF therapy, screening algorithms should maximise diagnostic sensitivity for detection of LTBI. Terbium 57-59 tumor necrosis factor Homo sapiens 86-89 18981763-5 2008 Surprisingly, numbers of phosphoantigen hydroxy-3-methyl-but-2-enyl pyrophosphate-specific IFNgamma+ Vgamma2Vdelta2+ T cells in the HIV + LTB group were much greater than those in the HIV + TB group (P < 0.001). Terbium 139-141 interferon gamma Homo sapiens 91-99 18680347-1 2008 The present investigation aims at the synthesis of KSr 1-x-y PO 4:Tb(3+) x Eu(2+) y phosphors using the combinatorial chemistry method. Terbium 66-68 kinase suppressor of ras 1 Homo sapiens 51-56 18817372-1 2008 In this paper, we present a facile and general synthetic route to high-quality alkaline earth metal fluoride (AEF2, AE = Ca, Sr, Ba) nanocrystals and CaF2:Tb(3+) nanocrystals based on the thermal decomposition of corresponding trifluoroacetate precursors in hot oleylamine. Terbium 155-157 CCR4-NOT transcription complex subunit 8 Homo sapiens 150-154 18817372-5 2008 Furthermore, we demonstrate the feasibility of introducing Tb(3+) ions into the CaF2 host via this method, which shows strong green emission corresponding to the characteristic (5)D4-(7)F(J) (J = 3, 4, 5, 6) emission of Tb(3+) ions, which can be potentially used as labels for biological molecules. Terbium 59-61 CCR4-NOT transcription complex subunit 8 Homo sapiens 80-84 18817372-5 2008 Furthermore, we demonstrate the feasibility of introducing Tb(3+) ions into the CaF2 host via this method, which shows strong green emission corresponding to the characteristic (5)D4-(7)F(J) (J = 3, 4, 5, 6) emission of Tb(3+) ions, which can be potentially used as labels for biological molecules. Terbium 220-222 CCR4-NOT transcription complex subunit 8 Homo sapiens 80-84 18692540-7 2008 We were also able to detect PPD-specific IFN-gamma release during short term culture of blood from a number of humans with active TB indicating that this test may have wider application and is potentially useful for the rapid diagnosis of disease in humans. Terbium 130-132 interferon gamma Homo sapiens 41-50 18853288-7 2008 In multivariate analysis, incidence of TB in country of origin was the strongest predictor of result of TST or T-SPOT.TB. Terbium 39-41 thiosulfate sulfurtransferase Homo sapiens 104-107 18853288-12 2008 Longitudinal data are needed to clarify the risk of TB in T-SPOT.TB+/TST- individuals. Terbium 52-54 thiosulfate sulfurtransferase Homo sapiens 69-72 19295106-9 2008 CONCLUSION: The presence of therapeutically inactive form of the EB2HCl from 30-100% in approximately 30% of the products in the local market is an alarming finding, which means low quality anti-TB products are in circulation. Terbium 195-197 microtubule associated protein RP/EB family member 2 Homo sapiens 65-68 18774804-3 2008 Crystallographic data for Tb2@C79N x Ni(OEP) x 2 C6H6 demonstrate the presence of an 80-atom cage with idealized I(h) symmetry and two, widely separated Tb atoms inside with a Tb-Tb separation of 3.9020(10) A for the major terbium sites. Terbium 153-155 receptor accessory protein 5 Homo sapiens 26-29 18774804-3 2008 Crystallographic data for Tb2@C79N x Ni(OEP) x 2 C6H6 demonstrate the presence of an 80-atom cage with idealized I(h) symmetry and two, widely separated Tb atoms inside with a Tb-Tb separation of 3.9020(10) A for the major terbium sites. Terbium 153-155 receptor accessory protein 5 Homo sapiens 26-29 18761435-6 2008 It involves rapid interaction of the 1:1 complex ML (M=In, L=NTA) with TB (T=transferrin, B=CO3(2-)) to give a quaternary intermediate MLTB which then evolves to an "open" MTB* ternary complex complex with expulsion of L. In turn, this complex interconverts to a "closed", more stable, form MTB. Terbium 71-73 transferrin Homo sapiens 77-88 21794559-5 2008 Nevertheless, later they have been published not controlled studies that show infections and TB in patients with RA that receive anti-TNFalpha drugs. Terbium 93-95 tumor necrosis factor Homo sapiens 134-142 18998325-1 2008 UNLABELLED: Romania decided and initiated a DRS for anti-TB drugs at national level using the standardized methodology proposed by WHO and IUATLD. Terbium 57-59 sushi repeat containing protein X-linked Homo sapiens 44-47 18558414-7 2008 Another group of toads treated with 2 mg kg(-1) (400 microg per animal) of l-NMMA or mCSF was submitted to hypoxia (3% inspired O(2)) for 8 h. The vehicle group showed a reduction of preferred Tb, a response that was inhibited by l-NMMA. Terbium 193-195 colony stimulating factor 2 (granulocyte-macrophage) Mus musculus 85-89 18699727-5 2008 Purified human C5a was labeled with terbium chelate and used as the fluorescence donor. Terbium 36-43 complement C5a receptor 1 Homo sapiens 15-18 18605682-2 2008 In the gas phase and in chloroform, the conformation tB with a trans depsipeptide bond is most preferred for the Lac dipeptide, whose backbone torsion angles are phi approximately -150 degrees and psi approximately -5 degrees , juxtaposed to those of the 3 10-helical structure. Terbium 53-55 lactase Homo sapiens 113-116 20165661-11 2008 CONCLUSION: ADA > 100IU/L was observed in TB only. Terbium 45-47 adenosine deaminase Homo sapiens 12-15 18560033-3 2008 Mutations of rpoB, katG, inhA and ahpC gene associated with rifampicin (RIF) and isoniazid (INH) resistance were detected by "TB-Biochip" test system. Terbium 126-128 inhibin subunit alpha Homo sapiens 25-29 18479146-3 2008 The deletion of htrA2 gives attenuated virulence in a mouse model of TB. Terbium 69-71 HtrA serine peptidase 2 Mus musculus 16-21 18482337-1 2008 In an attempt to design novel anti-TB drugs, the target chosen is the enzyme 6-hydroxymethyl-7,8-dihydropteroate synthase (DHPS), which is an attractive target since it is present in microorganisms but not in humans. Terbium 35-37 deoxyhypusine synthase Homo sapiens 123-127 18686610-2 2008 METHODS: We used ex vivo gamma-interferon enzyme-linked immunospot assays to test T cell responses to three novel gene products encoded by RD1 (Rv3873, Rv3878, and Rv3879c) in 49 patients (TB group) who were bacteriologically confirmed by positive cultures for MTB and 38 healthy BCG-vaccinated donors (control group). Terbium 189-191 phosphodiesterase 6B Homo sapiens 139-142 18355800-3 2008 We demonstrated that p27/Kip1, p21/Cip1 and the keratinocyte differentiation marker, human involucrin (hINV), were induced (>25 microM) in TB-induced differentiated A431 cells. Terbium 142-144 zinc ribbon domain containing 2 Homo sapiens 21-24 18355800-3 2008 We demonstrated that p27/Kip1, p21/Cip1 and the keratinocyte differentiation marker, human involucrin (hINV), were induced (>25 microM) in TB-induced differentiated A431 cells. Terbium 142-144 cyclin dependent kinase inhibitor 1B Homo sapiens 25-29 18355800-3 2008 We demonstrated that p27/Kip1, p21/Cip1 and the keratinocyte differentiation marker, human involucrin (hINV), were induced (>25 microM) in TB-induced differentiated A431 cells. Terbium 142-144 H3 histone pseudogene 16 Homo sapiens 31-34 18355800-3 2008 We demonstrated that p27/Kip1, p21/Cip1 and the keratinocyte differentiation marker, human involucrin (hINV), were induced (>25 microM) in TB-induced differentiated A431 cells. Terbium 142-144 cyclin dependent kinase inhibitor 1A Homo sapiens 35-39 18355800-5 2008 Immunocytochemical staining analysis showed that p27/Kip1, but not p21/Cip1, positive-stained cells were detected in the early-differentiated cells of TB-treated tumor tissues. Terbium 151-153 zinc ribbon domain containing 2 Homo sapiens 49-52 18355800-5 2008 Immunocytochemical staining analysis showed that p27/Kip1, but not p21/Cip1, positive-stained cells were detected in the early-differentiated cells of TB-treated tumor tissues. Terbium 151-153 cyclin dependent kinase inhibitor 1B Homo sapiens 53-57 18355800-6 2008 SP1, which regulates p27/Kip1 expression, was induced by TB (>10 microM) in A431 cells. Terbium 57-59 zinc ribbon domain containing 2 Homo sapiens 21-24 18355800-6 2008 SP1, which regulates p27/Kip1 expression, was induced by TB (>10 microM) in A431 cells. Terbium 57-59 cyclin dependent kinase inhibitor 1B Homo sapiens 25-29 18355800-7 2008 The TB-induced promoter activity and protein expression levels of p27/Kip1 were significantly attenuated by pretreatment with mithramycin A, a SP1 specific inhibitor. Terbium 4-6 zinc ribbon domain containing 2 Homo sapiens 66-69 18355800-7 2008 The TB-induced promoter activity and protein expression levels of p27/Kip1 were significantly attenuated by pretreatment with mithramycin A, a SP1 specific inhibitor. Terbium 4-6 cyclin dependent kinase inhibitor 1B Homo sapiens 70-74 18355800-10 2008 Such results suggest that SP1 plays a critical role in the p27/Kip1 gene transcriptional activation that may be subsequently involved in the TB-induced A431 cancer cell differentiation process. Terbium 141-143 zinc ribbon domain containing 2 Homo sapiens 59-62 18355800-10 2008 Such results suggest that SP1 plays a critical role in the p27/Kip1 gene transcriptional activation that may be subsequently involved in the TB-induced A431 cancer cell differentiation process. Terbium 141-143 cyclin dependent kinase inhibitor 1B Homo sapiens 63-67 18653907-11 2008 Among participants with CD4+ < 200 cells/microl, the prevalence of TB was 60 per cent. Terbium 70-72 CD4 molecule Homo sapiens 24-27 18173265-1 2008 The hydrothermal reaction of (L)-ethyl lactate (Lig-Et) with Tb(ClO(4))(3).6H(2)O gives colorless block (Lig)(2)Tb(H(2)O)(2)(ClO(4)) (1), in which 1 displays a laminar 2D framework. Terbium 61-63 ubiquitin conjugating enzyme E2 K Homo sapiens 48-51 18173265-1 2008 The hydrothermal reaction of (L)-ethyl lactate (Lig-Et) with Tb(ClO(4))(3).6H(2)O gives colorless block (Lig)(2)Tb(H(2)O)(2)(ClO(4)) (1), in which 1 displays a laminar 2D framework. Terbium 61-63 ubiquitin conjugating enzyme E2 K Homo sapiens 105-108 18173265-1 2008 The hydrothermal reaction of (L)-ethyl lactate (Lig-Et) with Tb(ClO(4))(3).6H(2)O gives colorless block (Lig)(2)Tb(H(2)O)(2)(ClO(4)) (1), in which 1 displays a laminar 2D framework. Terbium 112-114 ubiquitin conjugating enzyme E2 K Homo sapiens 48-51 18173265-1 2008 The hydrothermal reaction of (L)-ethyl lactate (Lig-Et) with Tb(ClO(4))(3).6H(2)O gives colorless block (Lig)(2)Tb(H(2)O)(2)(ClO(4)) (1), in which 1 displays a laminar 2D framework. Terbium 112-114 ubiquitin conjugating enzyme E2 K Homo sapiens 105-108 18173265-3 2008 Ferroelectricity of its analogue, (Lig)(2)Tb(D(2)O)(2)(ClO(4)) (2), further confirms the presence of the ferroelectric deuterium effect. Terbium 42-44 ubiquitin conjugating enzyme E2 K Homo sapiens 35-38 17964229-3 2008 We recently reported that in rat pups NMDA glutamate receptor limits Tb drop upon hypoxic exposure, an effect that has not been reported by others in adult rats. Terbium 69-71 glutamate ionotropic receptor NMDA type subunit 2C Rattus norvegicus 38-61 18239278-2 2008 In the present study, the transport activity of P-gp for sertraline, desmethylsertraline, bupropion, and the major metabolites of bupropion, threo-amino alcohol (TB), erythro-amino alcohol (EB), and hydroxy metabolite (HB) was studied using an ATPase assay in expressed human P-gp membranes by measuring concentrations of inorganic P(i) in expressed human P-gp membranes. Terbium 162-164 ATP binding cassette subfamily B member 1 Homo sapiens 48-52 17964229-6 2008 MK-801 amplified the magnitude of the hypoxic-induced Tb drop in P4, P10 and P20 rats, but this effect was not apparent in adults. Terbium 54-56 heat shock protein family B (small) member 6 Rattus norvegicus 77-80 18231607-1 2008 There is an increasing body of evidence which suggests that IL-4 plays a role in the pathogenesis of TB, but a general consensus on its role remains elusive. Terbium 101-103 interleukin 4 Homo sapiens 60-64 18003625-6 2008 Bcl2 mRNA content was correlated with protamine mRNA ratio (P = 0.0250 for TB; P = 0.0003 for E). Terbium 75-77 BCL2 apoptosis regulator Homo sapiens 0-4 18003625-7 2008 Infertile men exhibit a more than 10-fold (P = 0.0155 for TB; P = 7.0 x 10(-6) for E) higher Bcl2 mRNA content versus controls. Terbium 58-60 BCL2 apoptosis regulator Homo sapiens 93-97 18003625-10 2008 CONCLUSIONS: We found significantly aberrant protamine ratios and a higher Bcl2 content in TB and E of infertile men compared to controls, suggesting that these molecules may be useful biomarkers for predicting male infertility. Terbium 91-93 BCL2 apoptosis regulator Homo sapiens 75-79 18239278-8 2008 The results of the present study indicate that sertraline and desmethylsertraline have high affinity for P-gp, whereas bupropion and its three major metabolites TB, EB, and HB have very weak affinity for P-gp. Terbium 161-163 ATP binding cassette subfamily B member 1 Homo sapiens 204-208 18688837-10 2008 These results indicate that Pb(II), the most active metal ion, competes for Tb(III) binding differently from other metal ions such as Zn(II), suggesting that Pb(II) may bind to a different site from that for the other metal ions including Zn(II) and Tb(III). Terbium 76-78 submaxillary gland androgen regulated protein 3B Homo sapiens 28-34 18688837-10 2008 These results indicate that Pb(II), the most active metal ion, competes for Tb(III) binding differently from other metal ions such as Zn(II), suggesting that Pb(II) may bind to a different site from that for the other metal ions including Zn(II) and Tb(III). Terbium 76-78 submaxillary gland androgen regulated protein 3B Homo sapiens 158-164 18688837-10 2008 These results indicate that Pb(II), the most active metal ion, competes for Tb(III) binding differently from other metal ions such as Zn(II), suggesting that Pb(II) may bind to a different site from that for the other metal ions including Zn(II) and Tb(III). Terbium 250-252 submaxillary gland androgen regulated protein 3B Homo sapiens 28-34 18688837-10 2008 These results indicate that Pb(II), the most active metal ion, competes for Tb(III) binding differently from other metal ions such as Zn(II), suggesting that Pb(II) may bind to a different site from that for the other metal ions including Zn(II) and Tb(III). Terbium 250-252 submaxillary gland androgen regulated protein 3B Homo sapiens 158-164 18061950-11 2008 The use of PPD to stimulate CD4+IFN-gamma+ cells in the lung in active TB leads to >3-12-fold greater responses than seen with CFP-10 or ESAT-6, and any interference from BCG vaccination is absent. Terbium 71-73 CD4 molecule Homo sapiens 28-31 18061950-11 2008 The use of PPD to stimulate CD4+IFN-gamma+ cells in the lung in active TB leads to >3-12-fold greater responses than seen with CFP-10 or ESAT-6, and any interference from BCG vaccination is absent. Terbium 71-73 interferon gamma Homo sapiens 32-41 18061950-14 2008 In active TB, but not in BCG vaccinees, TB-specific memory CD4+ T cells can be found in blood that are dominantly CD27-negative and probably lung seeking and can be diagnostically useful. Terbium 10-12 CD4 molecule Homo sapiens 59-62 18061950-14 2008 In active TB, but not in BCG vaccinees, TB-specific memory CD4+ T cells can be found in blood that are dominantly CD27-negative and probably lung seeking and can be diagnostically useful. Terbium 10-12 CD27 molecule Homo sapiens 114-118 18061950-14 2008 In active TB, but not in BCG vaccinees, TB-specific memory CD4+ T cells can be found in blood that are dominantly CD27-negative and probably lung seeking and can be diagnostically useful. Terbium 40-42 CD4 molecule Homo sapiens 59-62 18061950-14 2008 In active TB, but not in BCG vaccinees, TB-specific memory CD4+ T cells can be found in blood that are dominantly CD27-negative and probably lung seeking and can be diagnostically useful. Terbium 40-42 CD27 molecule Homo sapiens 114-118 19065267-3 2008 IFN-gamma-inducible protein 10 (IP-10/CXCL10) has recently been evaluated as a marker for active TB in adults with promising results. Terbium 97-99 interferon gamma Homo sapiens 0-9 18444139-5 2008 In hypothalamus, ghrelin-infused TB rats exhibited significantly increased concentration of neuropeptide Y (NPY) as compared to saline-infused TB rats. Terbium 33-35 ghrelin and obestatin prepropeptide Rattus norvegicus 17-24 18444139-5 2008 In hypothalamus, ghrelin-infused TB rats exhibited significantly increased concentration of neuropeptide Y (NPY) as compared to saline-infused TB rats. Terbium 33-35 neuropeptide Y Rattus norvegicus 92-106 18444139-5 2008 In hypothalamus, ghrelin-infused TB rats exhibited significantly increased concentration of neuropeptide Y (NPY) as compared to saline-infused TB rats. Terbium 33-35 neuropeptide Y Rattus norvegicus 108-111 18444139-5 2008 In hypothalamus, ghrelin-infused TB rats exhibited significantly increased concentration of neuropeptide Y (NPY) as compared to saline-infused TB rats. Terbium 143-145 ghrelin and obestatin prepropeptide Rattus norvegicus 17-24 18444139-7 2008 Proopiomelanocortin message was reduced in ghrelin-infused and saline-infused TB rats as compared to noninfused TB control rats. Terbium 78-80 proopiomelanocortin Rattus norvegicus 0-19 18444139-7 2008 Proopiomelanocortin message was reduced in ghrelin-infused and saline-infused TB rats as compared to noninfused TB control rats. Terbium 112-114 proopiomelanocortin Rattus norvegicus 0-19 19065267-3 2008 IFN-gamma-inducible protein 10 (IP-10/CXCL10) has recently been evaluated as a marker for active TB in adults with promising results. Terbium 97-99 C-X-C motif chemokine ligand 10 Homo sapiens 32-37 19065267-3 2008 IFN-gamma-inducible protein 10 (IP-10/CXCL10) has recently been evaluated as a marker for active TB in adults with promising results. Terbium 97-99 C-X-C motif chemokine ligand 10 Homo sapiens 38-44 19065267-5 2008 METHOD: We measured IP-10 levels using ELISA in supernatants of whole blood samples stimulated with TB-specific-antigens and negative control antigen. Terbium 100-102 C-X-C motif chemokine ligand 10 Homo sapiens 20-25 19065267-6 2008 RESULTS: IP-10 is produced in high levels following mycobacterial antigen stimulation in active TB (n = 17) and LTBI (n = 16) compared to controls (n = 16) and to IFN-gamma. Terbium 96-98 C-X-C motif chemokine ligand 10 Homo sapiens 9-14 19065267-7 2008 The baseline levels of IP-10 are increased in active TB and in LTBI, but there is no significant difference of stimulated levels of IP-10 between active TB and LTBI. Terbium 53-55 C-X-C motif chemokine ligand 10 Homo sapiens 23-28 19065267-7 2008 The baseline levels of IP-10 are increased in active TB and in LTBI, but there is no significant difference of stimulated levels of IP-10 between active TB and LTBI. Terbium 64-66 C-X-C motif chemokine ligand 10 Homo sapiens 23-28 18077577-4 2007 MB and the related redox dyes toluidine blue O (TBO), thionine (TN), brilliant cresyl blue (BCB), and toluylene blue (TB) were reversible competitive inhibitors of both MAO-A and MAO-B and were highly selective toward MAO-A. Terbium 48-50 monoamine oxidase A Rattus norvegicus 169-174 18023090-4 2007 RESULTS: Statistical analysis revealed that the frequency of a variant haplotype, NAT2 6A, was significantly increased in TB patients with hepatotoxicity, compared with those without hepatotoxicity [P = 0.001, odds ratio (OR) = 3.535]. Terbium 122-124 N-acetyltransferase 2 Homo sapiens 82-86 18023090-7 2007 CONCLUSION: The present study shows that NAT2 is one of the determinants of anti-TB drug-induced hepatotoxicity. Terbium 81-83 N-acetyltransferase 2 Homo sapiens 41-45 18023090-8 2007 Moreover, the haplotypes, NAT2 4 and NAT2 6A, are useful new biomarkers for predicting anti-TB drug-induced hepatotoxicity. Terbium 92-94 N-acetyltransferase 2 Homo sapiens 26-30 18023090-8 2007 Moreover, the haplotypes, NAT2 4 and NAT2 6A, are useful new biomarkers for predicting anti-TB drug-induced hepatotoxicity. Terbium 92-94 N-acetyltransferase 2 Homo sapiens 37-41 17717055-6 2007 Collectively, the findings of this study suggest that hypothalamic AMPK activation reverses cancer anorexia by inhibiting the production of proinflammatory molecules and controlling the neuropeptide expression in the hypothalamus, reflecting in a prolonged life span in TB rats. Terbium 270-272 protein kinase AMP-activated catalytic subunit alpha 2 Rattus norvegicus 67-71 17935709-0 2007 Elevated level of serum LDH2 and LDH3 in sputum three positive TB patients of Sahariya tribe: a preliminary study. Terbium 63-65 lactate dehydrogenase C Homo sapiens 33-37 17766185-2 2007 The peripheral blood mononuclear cells of TB contacts showed maximum recognition in response to the combination of ESAT-6+MPT-64 in terms of predominant lymphoproliferation, IFN-gamma levels and the number of responders. Terbium 42-44 Fas (TNF receptor superfamily member 6) Mus musculus 153-172 17766185-2 2007 The peripheral blood mononuclear cells of TB contacts showed maximum recognition in response to the combination of ESAT-6+MPT-64 in terms of predominant lymphoproliferation, IFN-gamma levels and the number of responders. Terbium 42-44 interferon gamma Mus musculus 174-183 17608386-0 2007 Review: commercial interferon-gamma release assays have high specificity but suboptimal sensitivity for detecting latent TB. Terbium 121-123 interferon gamma Homo sapiens 19-35 17855170-5 2007 In HIV+TB+ patients, a significantly increased frequency of YA/YA diplotype (associated with very high MBL levels) was observed compared to controls (P=0.03). Terbium 7-9 mannose binding lectin 2 Homo sapiens 103-106 17855170-6 2007 In HIV+TB+ patients, a significantly decreased frequency of medium MBL expression diplotypes (XA/XA and YA/YO) were noticed compared to HIV+TB- and healthy controls. Terbium 7-9 mannose binding lectin 2 Homo sapiens 67-70 17855170-8 2007 Medium MBL expression diplotypes might protect against development of TB in HIV-infected patients. Terbium 70-72 mannose binding lectin 2 Homo sapiens 7-10 17573957-11 2007 RESULTS indicated that anti-TB drugs in combination: (i) caused membrane damage resulting in leakage of ALT, ALP and bilirubin; (ii) caused imbalance in endogenous enzymatic oxidant-antioxidant defense via increased lipid peroxidation and in glutathione homeostasis; and (iii) enhanced the CYP 2E1-mediated bioactivation mechanism. Terbium 28-30 cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus 290-297 18078110-3 2007 With CD4 count< 50/microL extrapulmonary TB is more common, and chest X-rays show lower and middle lobe and miliary infiltrates, usually without cavitation. Terbium 44-46 CD4 molecule Homo sapiens 5-8 18183335-7 2007 Targeting for rapid drug resistance detection, in hospitalized patients at "Servico de Pneumologia 2 do Hospital Pulido Valente", the test INNO-LIPA Rif.TB, to identify the rifampicin resistance as a marker of multi-drug resistance, was evaluated. Terbium 153-155 lipase A, lysosomal acid type Homo sapiens 144-148 18183335-10 2007 The INNO-LIPA Rif.TB test is, now, performed in every patient with smear-positive Tuberculosis with no previous knows resistance profile, with good outcome. Terbium 18-20 lipase A, lysosomal acid type Homo sapiens 9-13 17888914-4 2007 In combination, this experimentally validates TbNB as functional homologue of rat Tb15 in the human organism and clarifies the current composition of the human Tb family. Terbium 46-48 thymosin beta 15A Homo sapiens 82-86 17984934-6 2007 The novel non-synonymous mutation, c.3022T>C (C1008R) in the TB domain of FBN1 gene, may be involved in the pathogenesis of MFS in a Han Chinese family. Terbium 64-66 fibrillin 1 Homo sapiens 77-81 17995024-9 2007 For Ca1 we recover the leading order original calculation, where the VB mode coexists with TB. Terbium 91-93 carbonic anhydrase 1 Homo sapiens 4-7 17662590-7 2007 Comparing DQA1 alleles in both patient groups, DQA1*0501, DQA1*0505 alleles were more common and DQA1*03011, DQA1*0302, DQA1*0303 were less common after Bonferroni correction in SA than in TB. Terbium 189-191 major histocompatibility complex, class II, DQ alpha 1 Homo sapiens 10-14 17662590-8 2007 CONCLUSION: We revealed that DQA1*03011 allele was less common in SA than in the controls and TB. Terbium 94-96 major histocompatibility complex, class II, DQ alpha 1 Homo sapiens 29-33 18293704-10 2007 Thus, IFN-gamma, TNFalpha, IL-4, and IL5 production after 6 months-treatment decreased in moderate TB and increased in severe disease (p < 0.05). Terbium 99-101 interferon gamma Homo sapiens 6-15 18293704-10 2007 Thus, IFN-gamma, TNFalpha, IL-4, and IL5 production after 6 months-treatment decreased in moderate TB and increased in severe disease (p < 0.05). Terbium 99-101 interleukin 4 Homo sapiens 27-31 17110158-4 2007 To the Tb3+/Tm3+/Yb3+ triply doped glass system, a novel up-conversion mechanism is proposed as follows: the energy of (3)G(4) level (Tm3+) was transferred to (5)D(4) (Tb(3+)) and the 477-nm UC luminescence of Tm3+ was nearly quenched. Terbium 7-9 tropomyosin 3 Homo sapiens 12-15 18293704-10 2007 Thus, IFN-gamma, TNFalpha, IL-4, and IL5 production after 6 months-treatment decreased in moderate TB and increased in severe disease (p < 0.05). Terbium 99-101 interleukin 5 Homo sapiens 37-40 17110158-4 2007 To the Tb3+/Tm3+/Yb3+ triply doped glass system, a novel up-conversion mechanism is proposed as follows: the energy of (3)G(4) level (Tm3+) was transferred to (5)D(4) (Tb(3+)) and the 477-nm UC luminescence of Tm3+ was nearly quenched. Terbium 7-9 tropomyosin 3 Homo sapiens 134-137 17110158-4 2007 To the Tb3+/Tm3+/Yb3+ triply doped glass system, a novel up-conversion mechanism is proposed as follows: the energy of (3)G(4) level (Tm3+) was transferred to (5)D(4) (Tb(3+)) and the 477-nm UC luminescence of Tm3+ was nearly quenched. Terbium 7-9 tropomyosin 3 Homo sapiens 134-137 17475563-9 2007 These results indicate that a polymorphism in the NOS2A gene influences the susceptibility to TB and suggest a role for NOS2A in the pathogenesis of mycobacterial infection. Terbium 94-96 nitric oxide synthase 2 Homo sapiens 50-55 17478419-6 2007 We report herein the estimation of the metal-binding affinities of these predicted sites in the CaSR by monitoring aromatic-sensitized Tb(3+) fluorescence energy transfer. Terbium 135-137 calcium sensing receptor Homo sapiens 96-100 17433038-6 2007 In Late-TB mice, splenic MSC number intensively accumulated; the mRNA expressions of the signal transducer and activator of transcription 1, interferon regulatory factor 1 (IRF-1), and inducible nitric-oxide synthase (iNOS) were enhanced in MSC; the nitric oxide production and arginase enzyme activity increased in MSC as well. Terbium 8-10 signal transducer and activator of transcription 1 Mus musculus 89-139 17433038-7 2007 Furthermore, the concanavalin A-induced T cell proliferation was inhibited in the presence of lipopolysaccharide- or IFN-gamma-activated MSC from Late-TB mice, which could be reversed by the iNOS specific inhibitor L-NMMA. Terbium 151-153 interferon gamma Mus musculus 117-126 17433038-7 2007 Furthermore, the concanavalin A-induced T cell proliferation was inhibited in the presence of lipopolysaccharide- or IFN-gamma-activated MSC from Late-TB mice, which could be reversed by the iNOS specific inhibitor L-NMMA. Terbium 151-153 nitric oxide synthase 2, inducible Mus musculus 191-195 17453968-7 2007 CD34(+) cell recovery was higher with Sepax (86+/-11.6%) than with HES (81.5+/-12.5%) and TB (82.0+/-17.7%) (P<0.008 and <0.0001, respectively) and results with HES and TB were not significantly different (P=0.7). Terbium 90-92 CD34 molecule Homo sapiens 0-4 17507558-3 2007 TBS increased severalfold the numbers of spines containing phosphorylated (p) p21-activated kinase (PAK) or its downstream target cofilin; the latter regulates actin filament assembly. Terbium 0-3 cofilin 1 Homo sapiens 130-137 17302936-4 2007 Sequence alignment of pilQ derived from TB vs. PAO1 suggests that close direct repeats framing the deletion site may have triggered this mutation. Terbium 40-42 PilQ Pseudomonas aeruginosa 22-26 29788627-0 2007 NAT2 polymorphisms and their influence on the pharmacology and toxicity of isoniazid in TB patients. Terbium 88-90 N-acetyltransferase 2 Homo sapiens 0-4 17539288-6 2007 The mean serum ADA activity was significantly increased in patients with tubercular pleural effusion (34.53 +/- 10.27 IU/l) compared to pulmonary tuberculosis patients without pleural effusion (26.54 +/- 4.76 IU/l), (p = 0.004), those with non-TB respiratory disease (16.71 +/- 5.16 IU/l), (p = 0.0001) and healthy controls (15.53 +/- 4.4 IU/l) (p = 0.0001). Terbium 244-246 adenosine deaminase Homo sapiens 15-18 17539288-7 2007 The mean ADA in the pleural fluid of tubercular pleural effusion patients (90.29 +/- 54.80 IU/l) was significantly higher compared to those with non-TB respiratory disease (24.43 +/- 9.28 IU/l) (p = 0.0001). Terbium 149-151 adenosine deaminase Homo sapiens 9-12 17158965-2 2007 IFNgamma, a key cytokine in TB, usually inhibits MMP-9 secretion. Terbium 28-30 interferon gamma Homo sapiens 0-8 17158965-2 2007 IFNgamma, a key cytokine in TB, usually inhibits MMP-9 secretion. Terbium 28-30 matrix metallopeptidase 9 Homo sapiens 49-54 17158965-3 2007 Addition of IFNgamma to conditioned media from M. tb-infected monocytes (CoMTB) resulted in a 7-fold increase in MMP-9 activity detected by gelatin zymography (P<0.01). Terbium 50-52 interferon gamma Homo sapiens 12-20 17158965-3 2007 Addition of IFNgamma to conditioned media from M. tb-infected monocytes (CoMTB) resulted in a 7-fold increase in MMP-9 activity detected by gelatin zymography (P<0.01). Terbium 50-52 matrix metallopeptidase 9 Homo sapiens 113-118 17158965-7 2007 IL-1beta activity is dependent on p38 mitogen-activated protein (MAPK) kinase, which was found to be phosphorylated in tissue specimens from patients with CNS-TB. Terbium 159-161 interleukin 1 beta Homo sapiens 0-8 17158965-7 2007 IL-1beta activity is dependent on p38 mitogen-activated protein (MAPK) kinase, which was found to be phosphorylated in tissue specimens from patients with CNS-TB. Terbium 159-161 mitogen-activated protein kinase 1 Homo sapiens 34-37 17158965-7 2007 IL-1beta activity is dependent on p38 mitogen-activated protein (MAPK) kinase, which was found to be phosphorylated in tissue specimens from patients with CNS-TB. Terbium 159-161 mitogen-activated protein kinase 1 Homo sapiens 65-69 17263297-0 2007 Role of the C-reactive protein for the diagnosis of TB among military personnel in South Korea. Terbium 52-54 C-reactive protein Homo sapiens 12-30 17234300-5 2007 Based on two replicates of four pooled samples each, both NPY and AgRP mRNA appeared to be elevated in the VMA of anorectic TB rats, while only AgRP exhibited a similar increase in the DMA. Terbium 124-126 neuropeptide Y Rattus norvegicus 58-61 17234300-5 2007 Based on two replicates of four pooled samples each, both NPY and AgRP mRNA appeared to be elevated in the VMA of anorectic TB rats, while only AgRP exhibited a similar increase in the DMA. Terbium 124-126 agouti related neuropeptide Rattus norvegicus 66-70 17234300-6 2007 Levels of NPY were elevated in the VMA of both TB and pair-fed (PF) rats, but in the DMA only PF rats exhibited a significant NPY increase. Terbium 47-49 neuropeptide Y Rattus norvegicus 10-13 17386031-2 2007 Patients with pulmonary TB having similar allergic skin prick test sensitivity as healthy controls but unable to show vigorous atopic phenotype in their healthy period might be a sign for Th1-Th2 immune interaction. Terbium 24-26 negative elongation factor complex member C/D Homo sapiens 188-191 17453968-7 2007 CD34(+) cell recovery was higher with Sepax (86+/-11.6%) than with HES (81.5+/-12.5%) and TB (82.0+/-17.7%) (P<0.008 and <0.0001, respectively) and results with HES and TB were not significantly different (P=0.7). Terbium 175-177 CD34 molecule Homo sapiens 0-4 17192968-0 2006 Polyol-mediated synthesis of nanoscale CaF2 and CaF2:Ce,Tb. Terbium 56-58 CCR4-NOT transcription complex subunit 8 Homo sapiens 48-52 17365019-9 2007 Of particular interest was the decreased levels of the Th2 cytokine IL-4 in TB-derived samples. Terbium 76-78 heart and neural crest derivatives expressed 2 Mus musculus 55-58 17365019-9 2007 Of particular interest was the decreased levels of the Th2 cytokine IL-4 in TB-derived samples. Terbium 76-78 interleukin 4 Mus musculus 68-72 17299650-5 2007 The effect of AC on focus intensity was semiquantified by determination of the tumor-to-background (TB) ratio for SPECT(AC) and SPECT(NAC). Terbium 100-102 synuclein alpha Homo sapiens 134-137 17163576-6 2007 Five proteins, including creatine kinase and MHC class II antigens were found up-regulated in tonsils of TB+ boars. Terbium 105-107 MHC class II histocompatibility antigen SLA-DRB1 Sus scrofa 45-57 16973184-2 2006 We predicted that injection of L-NAME (non-selective NO synthase (NOS) inhibitor) and SMTC (neuronal NOS (nNOS) inhibitor) would restore the huddling behavior and eliminate the reduction of Tb caused by hypoxia. Terbium 190-192 nitric oxide synthase 1 Rattus norvegicus 92-104 16877037-1 2006 The strong fluorescence Tb/acetyl acetone (acac)/Poly (Acrylamide) (PAM) composite nanoparticles have been prepared under ultrasonic radiation. Terbium 24-26 peptidylglycine alpha-amidating monooxygenase Homo sapiens 68-71 17008485-0 2006 Whole blood IFN-gamma assay for detecting TB in children. Terbium 42-44 interferon gamma Homo sapiens 12-21 16766622-4 2006 Terbium binding and isothermal titration calorimetry data reveal that two atoms of Cu2+/Ca2+ bind per subunit of S100A13. Terbium 0-7 S100 calcium binding protein A13 Homo sapiens 113-120 17029383-3 2006 The hydration numbers obtained from luminescence lifetime measurements in aqueous solutions of the Eu(III) and Tb(III) complexes are q = 0.6 (EuL2), 0.7 (TbL2), 0.8 (EuL3), and 0.4 (TbL3). Terbium 111-113 transducin beta like 2 Homo sapiens 154-158 17029383-3 2006 The hydration numbers obtained from luminescence lifetime measurements in aqueous solutions of the Eu(III) and Tb(III) complexes are q = 0.6 (EuL2), 0.7 (TbL2), 0.8 (EuL3), and 0.4 (TbL3). Terbium 111-113 transducin beta like 3 Homo sapiens 182-186 16889744-3 2006 To assess how coregulator proteins interact with ERRgamma in response to ligand, an in vitro interaction methodology using time-resolved fluorescence resonance energy transfer (TR-FRET) was developed using glutathione S-transferase (GST)-tagged ERRgamma ligand-binding domain (LBD), a terbium-labeled anti-GST antibody, a fluorescein-labeled peptide containing sequences derived from coregulator proteins, and various ligands. Terbium 285-292 glutathione S-transferase kappa 1 Homo sapiens 233-236 16556901-3 2006 Because orexin is released during wakefulness and is thought to promote heat production, we hypothesized that orexin KO mice would have lower Tb while awake. Terbium 142-144 hypocretin Mus musculus 8-14 16556901-3 2006 Because orexin is released during wakefulness and is thought to promote heat production, we hypothesized that orexin KO mice would have lower Tb while awake. Terbium 142-144 hypocretin Mus musculus 110-116 16556901-5 2006 Orexin KO mice had normal diurnal variations in Tb, but the ultradian rhythms of Tb, locomotor activity, and wakefulness were markedly reduced. Terbium 48-50 hypocretin Mus musculus 0-6 16461017-4 2006 INT4 and D543N showed allelic association with pulmonary TB (P=0.02 and 0.03 respectively). Terbium 57-59 Wnt family member 3 Homo sapiens 0-4 16620953-4 2006 We found that PARN expressed from pET33 in BL21(DE3) grown in TB and induced at OD595 approximately 1 with 1 mM IPTG yielded mg amounts of soluble PARN per litre culture. Terbium 62-64 poly(A)-specific ribonuclease Homo sapiens 14-18 17058933-3 2006 PBD emission appears in the EL spectra of ITO/PVK: Tb complex/PBD/LiF/Al in comparison with ITO/PVK: Tb complex: PBD/PBD/LiF/Al. Terbium 51-53 LIF interleukin 6 family cytokine Homo sapiens 66-69 16898373-6 2006 The TST performed poorly in vaccinated persons of all ages from countries of low TB incidence, but was a useful screen for LTBI in vaccinated adults from countries of high and intermediate incidence. Terbium 81-83 thiosulfate sulfurtransferase Homo sapiens 4-7 16898373-9 2006 CONCLUSIONS: The usefulness of the TST as a screening method for LTBI depends on the age of the patient and the incidence of TB in their country of origin. Terbium 66-68 thiosulfate sulfurtransferase Homo sapiens 35-38 16784591-2 2006 METHODS: After the treatment in Tb cells with monoclonal antibodies (mAb) R5 of against Robo1 receptor extracellular domain, the apoptosis of Tb cell was examined by clone formation assay, flow cytometry, DNA ladder and Hochst-PI. Terbium 32-34 roundabout guidance receptor 1 Homo sapiens 88-93 16425263-10 2006 The biological relevance of this locally activated MMP-2 was underscored by the observation that only the TBS pattern of MMP-2 significantly correlated with decreased survival. Terbium 106-109 matrix metallopeptidase 2 Homo sapiens 51-56 16425263-10 2006 The biological relevance of this locally activated MMP-2 was underscored by the observation that only the TBS pattern of MMP-2 significantly correlated with decreased survival. Terbium 106-109 matrix metallopeptidase 2 Homo sapiens 121-126 16722616-3 2006 We investigated IFN-gamma responses to specific TB antigens among Indian health care workers (HCWs) before, and after LTBI preventive therapy. Terbium 48-50 interferon gamma Homo sapiens 16-25 16242741-4 2006 There were significantly higher initial levels of SR and TNF-alpha in HIV+/Tb+ patients (79 +/- 29 mm/h and 13.5 +/- 7.6 pg/ml), than in HIV-/Tb+ patients (60 +/- 23 mm/h and 6.8 +/- 5.9 pg/ml, P<0.001). Terbium 75-77 tumor necrosis factor Homo sapiens 57-66 16466744-7 2006 Furthermore, bathing crystals with the trivalent calcium ion mimic, Tb3+, results in anomalous scattering data that permit unequivocal localization of terbium ions in each of the proposed type I and type II ion-binding sites of both halves of gelsolin. Terbium 151-158 gelsolin Homo sapiens 243-251 16488659-1 2006 The fluorescence of Tb(3+) is sensitized by complexation with dibutylphosphate (DBP) and tri-n-butylphosphate (TBP). Terbium 20-22 TATA-box binding protein Homo sapiens 111-114 16700703-7 2006 The RD1 selected peptides assay had the highest diagnostic odds ratio for A-TB. Terbium 76-78 phosphodiesterase 6B Homo sapiens 4-7 16700703-8 2006 Thus, the results suggest that an assay based on RD1 selected peptides has a higher diagnostic accuracy for A-TB in a clinical setting compared with commercially available assays based on RD1 overlapping peptides. Terbium 110-112 phosphodiesterase 6B Homo sapiens 49-52 16644751-9 2006 Among these radiolanthanides, (161)Tb and (177)Lu are the only ones that can be produced no-carrier-added (nca) and with high specific activities. Terbium 35-37 CEA cell adhesion molecule 6 Homo sapiens 107-110 16113045-0 2005 Preventing TB in patients with Crohn"s disease needing infliximab or other anti-TNF therapy. Terbium 11-13 tumor necrosis factor Homo sapiens 80-83 17187661-8 2006 When the molecular and histomorphometric data were plotted, positive associations were observed in the controls for OCN/glyceraldehyde-3-phosphate dehydrogenase (GAPDH) versus bone tissue volume (r = 0.82, p < 0.0007) and OCN/GAPDH versus Tb.N (r = 0.56, p < 0.05) and a negative association was observed for OCN/GAPDH versus Tb.Sp (r = -0.64, p < 0.02). Terbium 242-244 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 116-160 17187661-8 2006 When the molecular and histomorphometric data were plotted, positive associations were observed in the controls for OCN/glyceraldehyde-3-phosphate dehydrogenase (GAPDH) versus bone tissue volume (r = 0.82, p < 0.0007) and OCN/GAPDH versus Tb.N (r = 0.56, p < 0.05) and a negative association was observed for OCN/GAPDH versus Tb.Sp (r = -0.64, p < 0.02). Terbium 242-244 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 162-167 17187661-8 2006 When the molecular and histomorphometric data were plotted, positive associations were observed in the controls for OCN/glyceraldehyde-3-phosphate dehydrogenase (GAPDH) versus bone tissue volume (r = 0.82, p < 0.0007) and OCN/GAPDH versus Tb.N (r = 0.56, p < 0.05) and a negative association was observed for OCN/GAPDH versus Tb.Sp (r = -0.64, p < 0.02). Terbium 242-244 bone gamma-carboxyglutamate protein Homo sapiens 116-119 17187661-8 2006 When the molecular and histomorphometric data were plotted, positive associations were observed in the controls for OCN/glyceraldehyde-3-phosphate dehydrogenase (GAPDH) versus bone tissue volume (r = 0.82, p < 0.0007) and OCN/GAPDH versus Tb.N (r = 0.56, p < 0.05) and a negative association was observed for OCN/GAPDH versus Tb.Sp (r = -0.64, p < 0.02). Terbium 332-334 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 116-160 17187661-8 2006 When the molecular and histomorphometric data were plotted, positive associations were observed in the controls for OCN/glyceraldehyde-3-phosphate dehydrogenase (GAPDH) versus bone tissue volume (r = 0.82, p < 0.0007) and OCN/GAPDH versus Tb.N (r = 0.56, p < 0.05) and a negative association was observed for OCN/GAPDH versus Tb.Sp (r = -0.64, p < 0.02). Terbium 332-334 glyceraldehyde-3-phosphate dehydrogenase Homo sapiens 162-167 17187661-8 2006 When the molecular and histomorphometric data were plotted, positive associations were observed in the controls for OCN/glyceraldehyde-3-phosphate dehydrogenase (GAPDH) versus bone tissue volume (r = 0.82, p < 0.0007) and OCN/GAPDH versus Tb.N (r = 0.56, p < 0.05) and a negative association was observed for OCN/GAPDH versus Tb.Sp (r = -0.64, p < 0.02). Terbium 332-334 bone gamma-carboxyglutamate protein Homo sapiens 116-119 16581924-0 2006 Thermoluminescence of terbium sensitised by samarium in CaF2. Terbium 22-29 CCR4-NOT transcription complex subunit 8 Homo sapiens 56-60 16184029-12 2005 With anti-TB treatment, IL-4 levels did not change whilst IL-4delta2 levels increased significantly. Terbium 10-12 interleukin 4 Homo sapiens 24-28 16455329-7 2006 RESULTS: At anorexia, hypothalamic NPY in arcuate nucleus (ARC) increased by 38% in TB-omega3FA versus TB-Control, whereas alpha-MSH decreased 64% in ARC and 29% in paraventricular nucleus (PVN). Terbium 84-86 neuropeptide Y Rattus norvegicus 35-38 17089872-4 2006 The diagnosis of TB in most of the world depends on the presence of a clinical illness typical for TB in concert with radiographic changes, the presence of AFB in sputum, or a positive TST. Terbium 17-19 thiosulfate sulfurtransferase Homo sapiens 185-188 17238344-1 2006 The PIH-EMR is a Web based electronic medical record that has been in operation for over four years in Peru supporting the treatment of drug resistant TB. Terbium 151-153 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 4-7 16381999-7 2006 RESULTS: Mann-Whitney rank sum tests showed that BMD of the LS, FN and TB was reduced by 14.8% (P < 0.001), 15.7% (P < 0.001), and 9.2% (P < 0.001) in CS vs. controls at baseline, with markedly reduced serum osteocalcin (P = 0.014) and increased CTX-1 (P = 0.012) levels, but no correlation between markers. Terbium 71-73 bone gamma-carboxyglutamate protein Homo sapiens 217-228 16262311-4 2005 The degree of hydration of Tb(III) on binding to DNA is followed by luminescence lifetime measurements in water and deuterium oxide solutions, and it is found that the lanthanide ion loses at least one hydration water on binding to long double stranded DNA at pH 4.7 and pH 7. Terbium 27-29 prolyl 4-hydroxylase, transmembrane Homo sapiens 260-264 16275946-6 2005 Using our selected peptides, IFN-gamma production, evaluated by both WBE and ELISPOT, was significantly higher in patients with A-TB than in controls (P < 0.0001). Terbium 130-132 interferon gamma Homo sapiens 29-38 16098953-4 2005 NPY markedly reduced Tb in the heterothermic Siberian hamster. Terbium 21-23 neuropeptide Y Rattus norvegicus 0-3 16202375-0 2005 When, and when not, to use the interferon-gamma TB test. Terbium 48-50 interferon gamma Homo sapiens 31-47 16165030-0 2005 Fluorimetric study of the interaction between human serum albumin and quinolones-terbium complex and its application. Terbium 81-88 albumin Homo sapiens 52-65 16098953-8 2005 NPY decreased 24-h food intake and this was exaggerated in the animals reaching criterion for torpor; the decrease in food intake was positively correlated with the magnitude of the decrease in Tb. Terbium 194-196 neuropeptide Y Rattus norvegicus 0-3 15860577-14 2005 Viewed collectively, these results support the hypothesis that TB-1-099 allosterically modulates hSERT binding and function. Terbium 63-65 solute carrier family 6 member 4 Homo sapiens 97-102 16104640-6 2005 However, the sensitivity of detection of TB in the presence of HIV increased to 87% by concomitant detection of circulating free and CIC serine protease antigen. Terbium 41-43 coagulation factor II, thrombin Homo sapiens 137-152 16104640-7 2005 CONCLUSION: Detection of free and CIC tuberculous serine protease antigen along with antibody is more useful for detecting TB in the presence of HIV co-infection. Terbium 123-125 coagulation factor II, thrombin Homo sapiens 50-65 15860577-7 2005 Using rat brain membranes, TB-1-099 weakly inhibited DAT binding (K(i) = 439 nM), was inactive at NET binding ([(3)H]nisoxetine), and partially inhibited SERT binding with an extrapolated plateau ("A" value) of 20%. Terbium 27-29 solute carrier family 6 member 4 Rattus norvegicus 154-158 16133992-6 2005 These findings may indicate that, during TB, predisposition of CD4 T-cells to apoptosis may involve both low expression of Bcl-2, and excessive expression of TGF-beta TNF-alpha and FasL. Terbium 41-43 BCL2 apoptosis regulator Homo sapiens 123-128 16133992-6 2005 These findings may indicate that, during TB, predisposition of CD4 T-cells to apoptosis may involve both low expression of Bcl-2, and excessive expression of TGF-beta TNF-alpha and FasL. Terbium 41-43 transforming growth factor beta 1 Homo sapiens 158-166 16133992-6 2005 These findings may indicate that, during TB, predisposition of CD4 T-cells to apoptosis may involve both low expression of Bcl-2, and excessive expression of TGF-beta TNF-alpha and FasL. Terbium 41-43 Fas ligand Homo sapiens 181-185 15927553-8 2005 In TB-omega-3FA vs. TB-Chow, NPY immunoreactivity increased 38% in arcuate nucleus (ARC; P < 0.05), and 50% in magnocellular paraventricular nucleus (mPVN; P < 0.05). Terbium 3-5 neuropeptide Y Rattus norvegicus 29-32 16021474-5 2005 Although no changes were found for these parameters, the maximal activities (by radioassay) of CPT I and II were reduced (P<0.05) in TB compared with controls. Terbium 136-138 carnitine palmitoyltransferase 1A Rattus norvegicus 95-100 16021474-6 2005 CPT II activity in the perivenous (PV) region was higher in TB compared with controls. Terbium 60-62 carnitine palmitoyltransferase 2 Rattus norvegicus 0-6 16135684-0 2005 Local IFN-{gamma} responses in TB. Terbium 31-33 interferon gamma Homo sapiens 6-16 16041416-1 2005 A novel surfactant-encapsulated terbium-substituted heteropolyoxotungstate complex [L1]13[Tb(SiW11O39)2].30H2O (SEC-1) bearing mesomorphous groups was successfully prepared by the ionic self-assembling route, exhibiting characteristic thermotropic liquid-crystalline behavior. Terbium 32-39 secretory blood group 1, pseudogene Homo sapiens 112-117 15955429-3 2005 We previously reported that 5-HT 1B-receptors are up regulated while NPY is down regulated in tumor-bearing (TB)-related anorexia, contributing to food intake reduction. Terbium 109-111 5-hydroxytryptamine receptor 1B Rattus norvegicus 28-35 15955429-3 2005 We previously reported that 5-HT 1B-receptors are up regulated while NPY is down regulated in tumor-bearing (TB)-related anorexia, contributing to food intake reduction. Terbium 109-111 neuropeptide Y Rattus norvegicus 69-72 15955429-4 2005 In anorectic TB rats we hypothesize that after tumor resection when food intake has reverted to normal, normalization of 5-HT 1B-receptor and NPY will occur. Terbium 13-15 5-hydroxytryptamine receptor 1B Rattus norvegicus 121-128 15955429-4 2005 In anorectic TB rats we hypothesize that after tumor resection when food intake has reverted to normal, normalization of 5-HT 1B-receptor and NPY will occur. Terbium 13-15 neuropeptide Y Rattus norvegicus 142-145 15836918-8 2005 Provision of unspecific NOS-antagonists to TB mice increased nNOS, eNOS and iNOS in several brain nuclei (PVN, LHA, VMH), but left tumor-induced anorexia unchanged. Terbium 43-45 nitric oxide synthase 1, neuronal Mus musculus 61-65 15687481-5 2005 Tb at resting periods was progressively decreased with declining Ta in HSA-mUCP1 transgenic mice but not in WT. Terbium 0-2 uncoupling protein 1 (mitochondrial, proton carrier) Mus musculus 75-80 15917089-5 2005 The CaM-CD2-III-5G-52 has stronger affinities to Ca(2+), Tb(3+) and La(3+) than CaM-CD2-IV-5G-52, indicating differential intrinsic metal-binding affinities of the EF-loops. Terbium 57-59 calmodulin 1 Homo sapiens 4-7 15917089-5 2005 The CaM-CD2-III-5G-52 has stronger affinities to Ca(2+), Tb(3+) and La(3+) than CaM-CD2-IV-5G-52, indicating differential intrinsic metal-binding affinities of the EF-loops. Terbium 57-59 CD2 molecule Homo sapiens 8-11 15955140-8 2005 Serum levels of IL-18 in the patients with P-TB correlated well with the extent of disease. Terbium 45-47 interleukin 18 Homo sapiens 16-21 15882069-4 2005 In competition studies with Tb(3+), the dissociation rates of Ca(2+) (k(off)) from the EF2 domains of S100B in the absence and presence of the p53 peptide was determined to be 60 and 7 s(-)(1), respectively. Terbium 28-30 S100 calcium binding protein B Homo sapiens 102-107 15836918-8 2005 Provision of unspecific NOS-antagonists to TB mice increased nNOS, eNOS and iNOS in several brain nuclei (PVN, LHA, VMH), but left tumor-induced anorexia unchanged. Terbium 43-45 nitric oxide synthase 2, inducible Mus musculus 76-80 15481852-6 2004 Both higher serum concentration of 1,25-(OH)2D3 and lower serum concentration of PTH were observed in the ESRD-TB group relative to the ESRD group, suggesting enhanced extrarenal production of 1,25-(OH)2D3 and suppressed secretion of PTH by hypercalcemia in the ESRD-TB group. Terbium 111-113 parathyroid hormone Homo sapiens 81-84 15708307-3 2005 PBMC from HCWs who developed TB showed decreased percentages of cells expressing CD8+CD25+ in comparison to HCWs who remained healthy. Terbium 29-31 interleukin 2 receptor subunit alpha Homo sapiens 85-89 16257833-5 2005 Of special interest are the nat genes of TB-causing Mycobacteria, since their protein products inactivate the anti-tubercular drug isoniazid. Terbium 41-43 bromodomain containing 2 Homo sapiens 28-31 15670956-4 2005 As an anti-TB drug target, Mtb-MAT has been well validated. Terbium 11-13 methionine adenosyltransferase 1A Homo sapiens 31-34 15607888-5 2005 The concentration of sf-COMP was higher in TB with an osteochondral fracture than in STB with osteochondral fractures and TB and STB with OA. Terbium 43-45 cartilage oligomeric matrix protein Equus caballus 24-28 15607888-9 2005 The increased concentration of sf-COMP in TB with osteochondral fractures, but not in synovial fluid from equine joints with OA, is a novel finding. Terbium 42-44 cartilage oligomeric matrix protein Equus caballus 34-38 20021081-4 2005 The treatments with D-penicillamine (D-PEN), ethylenediaminetetraacetic acid (EDTA), and MeOBGD reduced the content of Tb in the lung. Terbium 119-121 proprotein convertase subtilisin/kexin type 1 inhibitor Mus musculus 39-42 15378441-1 2004 We report the role of human neutrophil peptide (HNP)-1 as an adjunct to antituberculosis (anti-TB) drugs. Terbium 95-97 HNP1 Homo sapiens 28-54 15378441-5 2004 HNP-1 used in conjunction with anti-TB drugs resulted in significant clearance of bacterial load from lungs, liver, and spleen of infected, compared with control animals. Terbium 36-38 HNP1 Homo sapiens 0-5 15378441-7 2004 These results clearly suggest that HNP-1 can be used as adjunct chemotherapy with conventional drugs against TB. Terbium 109-111 HNP1 Homo sapiens 35-40 15821780-13 2005 TNFalpha significantly reduced (p<0.05) the blastocyst rates as well as TB and ICM. Terbium 75-77 tumor necrosis factor Mus musculus 0-8 15481852-6 2004 Both higher serum concentration of 1,25-(OH)2D3 and lower serum concentration of PTH were observed in the ESRD-TB group relative to the ESRD group, suggesting enhanced extrarenal production of 1,25-(OH)2D3 and suppressed secretion of PTH by hypercalcemia in the ESRD-TB group. Terbium 111-113 parathyroid hormone Homo sapiens 234-237 15481852-6 2004 Both higher serum concentration of 1,25-(OH)2D3 and lower serum concentration of PTH were observed in the ESRD-TB group relative to the ESRD group, suggesting enhanced extrarenal production of 1,25-(OH)2D3 and suppressed secretion of PTH by hypercalcemia in the ESRD-TB group. Terbium 267-269 parathyroid hormone Homo sapiens 81-84 15481852-8 2004 The ratio of 1,25-(OH)2D3 to PTH in serum was above 0.9 in the ESRD-TB group and below 0.9 in the ESRD group. Terbium 68-70 parathyroid hormone Homo sapiens 29-32 15643786-1 2004 Update for UAN affiliates on the Respiratory Protection Standard for TB. Terbium 69-71 zinc finger protein 365 Homo sapiens 11-14 15220699-6 2004 Seventeen completed combined standard TB and HIV therapy; 16 of 20 (80%) patients enrolled and 15 of 17 (88%) patients completing standard TB therapy achieved a viral load <50 copies/mL and mean CD4 count increase of 148 cells/mm(3). Terbium 139-141 CD4 molecule Homo sapiens 198-201 15311940-5 2004 The P450 has normal spectral features (including absolute absorbance, carbon monoxide, and ligand binding spectra), is efficiently reduced by TB and rat CPR but demonstrates altered specificity in comparison with human CYP51 toward three tested azole inhibitors, and contrary to the human, Candida albicans, and MT isoforms, reveals profound substrate preference toward obtusifoliol (turnover 5.6 min(-1)). Terbium 142-144 cytochrome P450 family 51 subfamily A member 1 Homo sapiens 219-224 15300190-9 2004 In TB-Resection versus NTB-Sham, 5-HT, DA, NPY, and FI normalized after tumor resection. Terbium 3-5 neuropeptide Y Rattus norvegicus 43-46 15005116-8 2004 But the slopes of decrease of MPF, MF, ZCR and Lempel-ziv complexity of TB were significantly steeper than those of BB. Terbium 72-74 mesothelin Homo sapiens 30-33 15185230-12 2004 Depletion of CD25+ cells before immunization restored response to mL26 in TB mice. Terbium 74-76 interleukin 2 receptor, alpha chain Mus musculus 13-17 15176595-4 2004 Peak latency of P300 was significantly longer for VS than for TB in both groups. Terbium 62-64 E1A binding protein p300 Homo sapiens 16-20 15176595-7 2004 The age showing the shortest P300 peak latency was younger for TB (20.3 years) than for VS (23.6 years). Terbium 63-65 E1A binding protein p300 Homo sapiens 29-33 15176595-8 2004 The P300 peak latency reduced around 10 years old more rapidly for VS than for TB. Terbium 79-81 E1A binding protein p300 Homo sapiens 4-8 15508808-11 2004 In the group of patients with the highest %TB, reaching 100%, the tKT value reached respectively 5, 10.8 and 13.6. Terbium 43-45 transketolase Homo sapiens 66-69 15508808-12 2004 The analysis of the relation between %TB and tKT showed a linear correlation of these two parameters. Terbium 38-40 transketolase Homo sapiens 45-48 15006598-3 2004 Intravenous injection of DOTAP:Chol-luciferase (luc) DNA complex resulted in tumor necrosis factor-alpha levels that were 50% lower and interleukin-10 levels that were 50-60% higher in TB mice than in NTB mice. Terbium 185-187 interleukin 10 Mus musculus 136-150 15006598-9 2004 Injection of anti-IL-10 antibody in TB mice resulted in a significant decrease in luc expression (P = 0.01) compared with that in mice injected with a control antibody. Terbium 36-38 interleukin 10 Mus musculus 18-23 15305487-9 2004 CONCLUSIONS: HLA-DRB1*07 and HLA-DQA1*0101 appeared to be the predisposing alleles and HLA-DQA1*0301 and 0501 the protective alleles in our patients with TB. Terbium 154-156 major histocompatibility complex, class II, DR beta 1 Homo sapiens 13-21 15305487-9 2004 CONCLUSIONS: HLA-DRB1*07 and HLA-DQA1*0101 appeared to be the predisposing alleles and HLA-DQA1*0301 and 0501 the protective alleles in our patients with TB. Terbium 154-156 major histocompatibility complex, class II, DQ alpha 1 Homo sapiens 29-37 15305487-9 2004 CONCLUSIONS: HLA-DRB1*07 and HLA-DQA1*0101 appeared to be the predisposing alleles and HLA-DQA1*0301 and 0501 the protective alleles in our patients with TB. Terbium 154-156 major histocompatibility complex, class II, DQ alpha 1 Homo sapiens 87-95 15100408-1 2004 The conformational space sampled by the two-domain protein calmodulin has been explored by an approach based on four sets of NMR observables obtained on Tb(3+)- and Tm(3+)-substituted proteins. Terbium 153-155 calmodulin 1 Homo sapiens 59-69 15048957-6 2004 The average ASC:SIL ratios pre- and postimplementation of TBS 2001 were 1.52:1 and 1.42:1, respectively. Terbium 58-61 PYD and CARD domain containing Homo sapiens 12-15 15048957-6 2004 The average ASC:SIL ratios pre- and postimplementation of TBS 2001 were 1.52:1 and 1.42:1, respectively. Terbium 58-61 STIL centriolar assembly protein Homo sapiens 16-19 14698305-4 2004 Enzymes that synthesize MSH are attractive candidates for the design of novel anti-TB drugs because of the importance of MSH for mycobacterial life and the absence of such enzymes in humans. Terbium 83-85 msh homeobox 2 Homo sapiens 24-27 14698305-4 2004 Enzymes that synthesize MSH are attractive candidates for the design of novel anti-TB drugs because of the importance of MSH for mycobacterial life and the absence of such enzymes in humans. Terbium 83-85 msh homeobox 2 Homo sapiens 121-124 15127942-6 2003 These results suggest that the POMC alpha-MSH satiety system is refractory in TB rats, even prior to the onset of anorexia. Terbium 78-80 proopiomelanocortin Rattus norvegicus 31-35 15231452-5 2004 However, the elevated concentration of NPY in the VMH of anorectic TB rats was also normalized by the DCA treatment. Terbium 67-69 neuropeptide Y Rattus norvegicus 39-42 14741405-2 2004 The TB motif (located at nts -900/-872 relative to the neuronal cap site) bears striking similarities with the dimeric Pit-1 binding site from growth hormone gene promoter (GH-1), and it enhanced the activity of the minimal tk promoter in transfected SK-N-BE neuroblastoma cells. Terbium 4-6 growth hormone 1 Homo sapiens 173-177 14741405-5 2004 We now show that both TB and ONF sites participate in the activation of the neuronal promoter by Brn-2. Terbium 22-24 POU class 3 homeobox 2 Homo sapiens 97-102 14741405-6 2004 EMSA experiments showed that the recombinant Brn-2 POU domain dimerized on the TB element in a cooperative manner. Terbium 79-81 POU class 3 homeobox 2 Homo sapiens 45-50 14741405-7 2004 By site directed mutagenesis of the POU domain of Brn-2, the dimerization interface on the TB element was localized to the hydrophobic pocket of the POU specific domain and the C-terminal part of the POU homeodomain. Terbium 91-93 POU class 3 homeobox 2 Homo sapiens 50-55 15127942-6 2003 These results suggest that the POMC alpha-MSH satiety system is refractory in TB rats, even prior to the onset of anorexia. Terbium 78-80 proopiomelanocortin Rattus norvegicus 36-45 15127942-8 2003 Cytokine involvement in the altered response to MC3/MC4 receptor stimulation and blockade is a possibility, since TNF-alpha and IL-2 were increased in hypothalamus of anorectic TB rats. Terbium 177-179 tumor necrosis factor Rattus norvegicus 114-123 15127942-8 2003 Cytokine involvement in the altered response to MC3/MC4 receptor stimulation and blockade is a possibility, since TNF-alpha and IL-2 were increased in hypothalamus of anorectic TB rats. Terbium 177-179 interleukin 2 Rattus norvegicus 128-132 14682409-4 2003 RESULTS: The pleural fluid Levels of IL-6, TNF-alpha and IFN-gamma in TB patients were significantly higher than those with non-TB effusions (P values of <0.001, 0.018 and <0.001, respectively by independent t-test). Terbium 70-72 interleukin 6 Homo sapiens 37-41 14682409-4 2003 RESULTS: The pleural fluid Levels of IL-6, TNF-alpha and IFN-gamma in TB patients were significantly higher than those with non-TB effusions (P values of <0.001, 0.018 and <0.001, respectively by independent t-test). Terbium 70-72 tumor necrosis factor Homo sapiens 43-52 14682409-4 2003 RESULTS: The pleural fluid Levels of IL-6, TNF-alpha and IFN-gamma in TB patients were significantly higher than those with non-TB effusions (P values of <0.001, 0.018 and <0.001, respectively by independent t-test). Terbium 70-72 interferon gamma Homo sapiens 57-66 14607119-0 2003 Solution structure of the third TB domain from LTBP1 provides insight into assembly of the large latent complex that sequesters latent TGF-beta. Terbium 32-34 latent transforming growth factor beta binding protein 1 Homo sapiens 47-52 14607119-0 2003 Solution structure of the third TB domain from LTBP1 provides insight into assembly of the large latent complex that sequesters latent TGF-beta. Terbium 32-34 transforming growth factor beta 1 Homo sapiens 135-143 14607119-8 2003 In order to clarify the basis of TB domain function, we have determined the solution NMR structure of TB3(LTBP1). Terbium 33-35 latent transforming growth factor beta binding protein 1 Homo sapiens 106-111 15227883-5 2003 Among the 10 HIV-positive participants who subsequently developed TB disease, the CD4 count was low (median 201/microliter, range 45-419), and viral load high (median 4.97 log copies/ml, range 3.70-5.58), at the routine follow-up visit prior to TB diagnosis. Terbium 66-68 CD4 molecule Homo sapiens 82-85 14598973-4 2003 ICE activity was significantly lower in TB patients (65.3 +/- 34.4 vs. 142.2 +/- 75.6 U/mg) (P < 0.05). Terbium 40-42 caspase 1 Homo sapiens 0-3 23105392-7 2003 The sensitivity of ERBA LISA test in tuberculous meningitis and genito-urinary TB was significantly low (26.6% & 40% respectively) compared to sensitivity obtained using SEVA TB ELISA (86.6% & 60% respectively) with overall specificity of 60% and 87.5%. Terbium 79-81 thyroid hormone receptor alpha Homo sapiens 19-23 12780691-5 2003 IFN-gamma production was depressed significantly in all groups of TB patients compared with the HTR group. Terbium 66-68 interferon gamma Homo sapiens 0-9 12736818-6 2003 ELISA results showed that IFN-gamma production following stimulation with the 30-kDa Ag was significantly lower in each group of TB patients than in the HTR controls. Terbium 129-131 interferon gamma Homo sapiens 26-35 14603964-2 2003 The Private Practitioners (PPs) involved in Public-Private Mix (PPM) in India"s RNTCP are the first point of contact for more than 2/3rds of TB symptomatics. Terbium 141-143 Mix paired-like homeobox Homo sapiens 59-62 12735118-6 2003 New guidelines for the treatment of LTBI emphasize targeted TST among persons at high risk for development of active TB and no longer use age as an exclusionary condition. Terbium 37-39 thiosulfate sulfurtransferase Homo sapiens 60-63 16167723-16 2003 Among the HIV-1 infected children, only TB, parotiditis, and acute otitis media (AOM) were significantly associated with decreased CD4+ T cell count (p<0.05) resulting from HIV infection. Terbium 40-42 CD4 molecule Homo sapiens 131-134 12588010-5 2003 Among the 10 HIV-positive participants who subsequently developed TB disease, the CD4 count was low (median 201/microl, range 45-419), and viral load high (median 4.97 log copies/ml, range 3.70-5.58), at the routine follow-up visit prior to TB diagnosis. Terbium 66-68 CD4 molecule Homo sapiens 82-85 12819375-6 2002 Allelic frequencies of AlbB, ESI, TFD and TFF1 were high in TB. Terbium 60-62 trefoil factor 1 Equus caballus 42-46 12535782-4 2003 NPY-immunoreactive neurons were visualized in Control and anorectic TB rats in the preoptic region, the arcuate nucleus, and occasionally in the lateral hypothalamus. Terbium 68-70 neuropeptide Y Rattus norvegicus 0-3 12535782-5 2003 Semiquantitative image analysis showed a significant decrease in the NPY immunostaining in some hypothalamic nuclei of the anorectic TB rats, most prominently in the supraoptic nucleus, the parvocellular portion of the paraventricular nucleus, and, to a lesser extent, the suprachiasmatic and arcuate nuclei. Terbium 133-135 neuropeptide Y Rattus norvegicus 69-72 12535782-7 2003 The data support the hypothesis of an altered hypothalamic NPY system at the onset of anorexia in TB rats and also reveal the hypothalamic nuclei through which NPY influences food intake. Terbium 98-100 neuropeptide Y Rattus norvegicus 59-62 12572798-1 2003 Screening of a small library of tripod ligands resulted in the discovery of bis(2-pyridylmethyl)-(2-hydroxybenzyl)amine (HL1) as a new sensitiser, which is able to transfer its excitation energy to terbium(III). Terbium 198-205 intelectin 1 Homo sapiens 121-124 12574446-1 2003 We have previously reported that varying stimulus intensity produces qualitatively different types of synaptic plasticity in area CA1 of hippocampal slices: brief low-intensity (LI) theta-burst (TB) stimuli induce long-term potentiation (LTP), but if the stimulus intensity is increased (to mimic conditions that may exist during seizures), LTP is not induced; instead, high-intensity (HI) TB stimuli erase previously induced LTP ("TB depotentiation"). Terbium 195-197 carbonic anhydrase 1 Rattus norvegicus 130-133 12574446-3 2003 We found that TB depotentiation was blocked by okadaic acid and calyculin A (inhibitors of serine/threonine protein phosphatases PP1 and PP2A), FK506 (a specific blocker of calcineurin, a Ca(2+)/calmodulin (CaM) protein phosphatase), and 8-Br-cAMP (an activator of protein kinase A) with 3-isobutyl-1-methylxanthine (IBMX, a phosphodiesterase inhibitor). Terbium 14-16 neuropeptide Y receptor Y4 Rattus norvegicus 129-132 12635507-5 2003 Furthermore, experimental data from in vitro investigations and animal models demonstrate a link between decreased TNF alpha activity and increased susceptibility to TB. Terbium 166-168 tumor necrosis factor Homo sapiens 115-124 12527624-5 2003 IFN-gamma is emerging as an important cytokine for use in the treatment of patients with infectious diseases, including multidrug-resistant pulmonary TB. Terbium 150-152 interferon gamma Homo sapiens 0-9 12793733-0 2002 Thermoluminescence in sintered CaF2:Tb. Terbium 36-38 CCR4-NOT transcription complex subunit 8 Homo sapiens 31-35 12793733-3 2002 The TL intensity from CaF2:Tb was the highest among the samples doped other lanthanide elements. Terbium 27-29 CCR4-NOT transcription complex subunit 8 Homo sapiens 22-26 12793733-5 2002 The TL peaks are observed at about 353 K, 378 K and 458 K. It was found that the 378 K TL peak intensity of CaF2:Tb became strong by addition of Sm2O3. Terbium 113-115 CCR4-NOT transcription complex subunit 8 Homo sapiens 108-112 12357811-1 2002 The coordinately unsaturated terbium complexes Tb.1 and Tb.2 possess two labile metal-bound water molecules that can be displaced upon metal chelation to aromatic carboxylic anions such as salicylic acid in water, which gives rise to large enhancements in the Tb(III) luminescence. Terbium 47-49 receptor accessory protein 5 Homo sapiens 56-60 11909487-1 2002 We propose an electronic spin-filter device that uses a nonmagnetic triple barrier resonant tunneling diode (TB-RTD). Terbium 109-111 spindlin 1 Homo sapiens 25-29 12370992-12 2002 This undoubtedly reflects the select population with an extremely high rate of TB and resultant bronchiectasis leading to NTM infection. Terbium 79-81 neurotrimin Homo sapiens 122-125 12370992-26 2002 It has been speculated that infection with TB [29,38] and Bacillus Calmette-Guerin (BCG) [19,68] may provide cross-immunity protecting against NTM infection. Terbium 43-45 neurotrimin Homo sapiens 143-146 12200539-4 2002 The addition of protein concentration to Tb(III) solution results in a large enhancement of Tb(III) fluorescence due to energy transfer between terbium ions and aromatic residues in CD2-D1. Terbium 144-151 CD2 molecule Homo sapiens 182-185 12022826-5 2002 Removal of two TBS protecting groups to reveal the C15 and C20 hydroxyls occurred without rearrangement to isolaulimalide. Terbium 15-18 placenta associated 8 Homo sapiens 51-54 11996601-3 2002 Here, Ce(3+), Tb(3+), Dy(3+), Ho(3+), Er(3+), Tm(3+), Yb(3+) in the C-terminal site of calbindin D(9k) have been investigated. Terbium 14-16 S100 calcium binding protein G Homo sapiens 87-101 12073618-3 2002 At the time of diagnosis, IFN-gamma production by CD4+ T cells in either tuberculosis patients without DM (TB) or with DM was significantly lower than that in the healthy control. Terbium 107-109 interferon gamma Homo sapiens 26-35 12073618-4 2002 CD4+ T cells in tuberculosis patients with DM under poor control (DM(p)TB) produced significantly less IFN-gamma than did patients with DM under good control (DM(g)TB). Terbium 71-73 interferon gamma Homo sapiens 103-112 12073618-5 2002 In longitudinal studies, IFN-gamma production in both TB and DM(g)TB patients returned to the control level by 6 months, whereas the production in DM(p)TB patients remained depressed. Terbium 54-56 interferon gamma Homo sapiens 25-34 12073618-5 2002 In longitudinal studies, IFN-gamma production in both TB and DM(g)TB patients returned to the control level by 6 months, whereas the production in DM(p)TB patients remained depressed. Terbium 66-68 interferon gamma Homo sapiens 25-34 12073618-5 2002 In longitudinal studies, IFN-gamma production in both TB and DM(g)TB patients returned to the control level by 6 months, whereas the production in DM(p)TB patients remained depressed. Terbium 66-68 interferon gamma Homo sapiens 25-34 12067307-9 2002 Our findings suggest that patients with MDRTB have dysregulated IL-12, IL-18 and IL-10 production during Mycobacterium tuberculosis infection, and the cytokine profiles are similar to those in patients with drug-sensitive advanced TB previously reported in the literature. Terbium 43-45 interleukin 18 Homo sapiens 71-76 12067307-9 2002 Our findings suggest that patients with MDRTB have dysregulated IL-12, IL-18 and IL-10 production during Mycobacterium tuberculosis infection, and the cytokine profiles are similar to those in patients with drug-sensitive advanced TB previously reported in the literature. Terbium 43-45 interleukin 10 Homo sapiens 81-86 12000217-6 2002 The BuChE activity dropped from 5.24 mU/mg in NB to 3.39 mU/mg in TB (p = 0.002). Terbium 66-68 butyrylcholinesterase Homo sapiens 4-9 12000217-7 2002 Glycolipid-linked AChE dimers and monomers and hydrophilic BuChE tetramers and monomers were identified in NB and TB, and their proportions were unmodified by the neoplasia. Terbium 114-116 butyrylcholinesterase Homo sapiens 59-64 11850089-6 2002 The TB-P300 amplitudes were significantly negatively correlated with thought disorders remaining after treatment and were positively correlated with age of onset. Terbium 4-6 E1A binding protein p300 Homo sapiens 7-11 11850089-7 2002 Illness duration was significantly correlated to TB-P300 and TS-P300 amplitudes in the group of patients with late onset. Terbium 49-51 E1A binding protein p300 Homo sapiens 52-56 11801790-6 2001 Using a specific CK15 antibody, 38% of TB showed a focal labeling and all BCC remained negative; 70% of TB and 22% of BCC expressed CK19. Terbium 39-41 keratin 15 Homo sapiens 17-21 11936108-5 2002 The TB CAT procedure is illustrated by a flow diagram and a case study of Nd(III) complexation by picolinic acid N-oxide (pic NO) in aqueous solution. Terbium 4-6 catalase Homo sapiens 7-10 11743664-4 2002 The ALP activity was enhanced in a dose-dependent manner up to 180-fold by 1 mM TB. Terbium 80-82 alkaline phosphatase, placental Homo sapiens 4-7 11811784-1 2001 Expression of CXCR4 was significantly reduced from normal on all cell subsets of persons with pulmonary tuberculosis (TB group), with HIV-1 infection (HIV group), and those with both infections (HIV/TB group), except for on monocytes in the HIV group. Terbium 118-120 C-X-C motif chemokine receptor 4 Homo sapiens 14-19 11811784-4 2001 By contrast, CCR5 expression on most cell subsets analyzed was increased in all the disease groups, except for on monocytes in the two TB groups. Terbium 135-137 C-C motif chemokine receptor 5 Homo sapiens 13-17 11521912-6 2001 When using a capillary filled with 1.5 M TB buffer, pH 10.0, and PEO solution prepared in 800 mM TB buffer, pH 9.0, the LOD values for CA and alpha-lac were 13.8 nM and 126.0 nM, respectively, which were about 4.7 and 11.2-fold sensitivity enhancements compared to those obtained by a conventional hydrodynamic injection (30 cm height for 10 s), respectively. Terbium 97-99 lactalbumin alpha Homo sapiens 142-151 11920913-10 2001 Fluorescence of PON1 complexed to terbium ion shows that at least one tryptophan is close to the calcium binding site. Terbium 34-41 paraoxonase 1 Homo sapiens 16-20 11761444-7 2001 Also the IFN-gamma production and cytotoxicity against the wild-type tumor cells and the NK sensitive YAC cells were depressed in spleen cells of TB rats after 5-day restimulation with wild-type tumor cells. Terbium 146-148 interleukin 18 Rattus norvegicus 9-18 11801790-6 2001 Using a specific CK15 antibody, 38% of TB showed a focal labeling and all BCC remained negative; 70% of TB and 22% of BCC expressed CK19. Terbium 104-106 keratin 15 Homo sapiens 17-21 11801790-7 2001 CK8 was expressed by numerous Merkel cells present in all TB but in none of the BCC examined. Terbium 58-60 keratin 8 Homo sapiens 0-3 10943070-9 2000 The present study suggested that the genotype tt of vitamin D receptor gene may be associated with susceptibility to pulmonary TB in female patients, and the genotype TT may be associated with resistance in female contacts. Terbium 127-129 vitamin D receptor Homo sapiens 52-70 11170995-2 2001 A significant reduction in the fluorescence intensity of CD88 on PMNL was observed in the HIV and HIV/TB groups, compared with both the healthy donor (HD) and TB groups. Terbium 102-104 complement C5a receptor 1 Homo sapiens 57-61 11899696-3 2001 In recent years particular polymorphisms of several human genes have been shown to be correlated with susceptibility to TB: NRAMP1, Vitamin D receptor, Interferon gamma receptor, IL-12 and its receptor, several HLA haplotypes and there are probably several others that will be discovered. Terbium 120-122 solute carrier family 11 member 1 Homo sapiens 124-130 11899696-3 2001 In recent years particular polymorphisms of several human genes have been shown to be correlated with susceptibility to TB: NRAMP1, Vitamin D receptor, Interferon gamma receptor, IL-12 and its receptor, several HLA haplotypes and there are probably several others that will be discovered. Terbium 120-122 vitamin D receptor Homo sapiens 132-150 11156391-14 2000 This research warrants a prospective trial to corroborate the usefulness of gene diagnosis of UGT1A1 polymorphisms prior tb irinotecan chemotherapy. Terbium 121-123 UDP glucuronosyltransferase family 1 member A1 Homo sapiens 94-100 11004547-3 2000 Sensitized luminescence arising from resonance energy transfer from epsilon-adenine to Tb(3+) is quenched by PDI. Terbium 87-89 prolyl 4-hydroxylase subunit beta Homo sapiens 109-112 11067810-4 2000 Free and total PSA were detected with europium- or terbium-labeled Fab fragments on a single microparticle using a microfluorometer in a time-resolved mode. Terbium 51-58 FA complementation group B Homo sapiens 67-70 10901810-0 2000 Western Cape MEC toughens up on TB. Terbium 32-34 C-C motif chemokine ligand 28 Homo sapiens 13-16 10872850-5 2000 C3a was significantly higher (p=0.02) in the TBS group after 30 minutes of CPB, but the C3a increase after protamine administration was significantly less pronounced in the TBS group vs. the control group. Terbium 173-176 complement C3 Homo sapiens 88-91 10872850-5 2000 C3a was significantly higher (p=0.02) in the TBS group after 30 minutes of CPB, but the C3a increase after protamine administration was significantly less pronounced in the TBS group vs. the control group. Terbium 45-48 complement C3 Homo sapiens 0-3 10847479-7 2000 Compared to IL-6+/+ controls, IL-6-/- mice showed slightly less BEC proliferation, a trend toward more liver injury, and significantly higher total serum bilirubin (TB) levels, suggestive of impaired biliary tree integrity. Terbium 165-167 interleukin 6 Mus musculus 30-34 10916272-6 2000 Following administration of synthetic ACTH (cosyntropin), the 30 and 60 minutes mean serum cortisol values in the TB group were significantly lower as compared to the normal control group (p < 0.05). Terbium 114-116 proopiomelanocortin Homo sapiens 38-42 10423959-8 1999 Diverse cytokines are known to play an important role in anti-TB cell-mediated immunity, including IL-2, IL-12, IL-18 and IFN-gamma. Terbium 62-64 interleukin 2 Homo sapiens 99-103 10620552-7 2000 Repeated-measures analysis of variance comparing the run-in phase with the trial phase showed that PMO TNFalpha release was significantly elevated in patients treated with both TB (P = 0.040) and TBL (P = 0.014) but not in patients treated with Lac-PDF (P = 0. Terbium 177-179 tumor necrosis factor Homo sapiens 103-111 10691916-8 2000 TNF-alpha secretion was enhanced in the presence of TB plasma (4/8) but not in the presence of control plasma. Terbium 52-54 tumor necrosis factor Homo sapiens 0-9 10695268-8 2000 In TB rats, intra-VMN mianserin or IL-1ra selectively increased meal number, leading to improved food intake. Terbium 3-5 interleukin 1 receptor antagonist Rattus norvegicus 35-41 10471799-1 1999 In the present work, we studied the interactions of recombinant alpha1 and alpha2 integrin I domains with cations Tb(3+), Mn(2+), Mg(2+) and Ca(2+). Terbium 114-116 adrenoceptor alpha 1D Homo sapiens 64-70 10423959-11 1999 Clinical trial of inhalation therapy with IFN-gamma showed some improvement for drug-resistant TB. Terbium 95-97 interferon gamma Homo sapiens 42-51 10421441-9 1999 The luminescence spectrum of the PON terbium complex exhibited an emission peak at 545 nm characteristic of an aromatic residue (Trp and/or Tyr)-terbium interaction. Terbium 37-44 paraoxonase 1 Homo sapiens 33-36 10421441-9 1999 The luminescence spectrum of the PON terbium complex exhibited an emission peak at 545 nm characteristic of an aromatic residue (Trp and/or Tyr)-terbium interaction. Terbium 145-152 paraoxonase 1 Homo sapiens 33-36 10225834-3 1999 In contrast, PMNLs from the HIV and HIV/TB groups responded reciprocally in the same assay; that is, higher IL-8 input concentrations resulted in the release of less enzyme than lower IL-8 input concentrations. Terbium 40-42 C-X-C motif chemokine ligand 8 Homo sapiens 108-112 10225834-3 1999 In contrast, PMNLs from the HIV and HIV/TB groups responded reciprocally in the same assay; that is, higher IL-8 input concentrations resulted in the release of less enzyme than lower IL-8 input concentrations. Terbium 40-42 C-X-C motif chemokine ligand 8 Homo sapiens 184-188 12496823-1 1999 We have developed a direct immunofluorescence technique utilising chelates of the lanthanide ions europium and terbium conjugated to monoclonal IgGs (Mabs) against prostate-specific antigen (PSA) and alpha-1-antichymotrypsin (ACT) for the detection and quantification on the same tissue section. Terbium 111-118 kallikrein related peptidase 3 Homo sapiens 164-195 12496823-1 1999 We have developed a direct immunofluorescence technique utilising chelates of the lanthanide ions europium and terbium conjugated to monoclonal IgGs (Mabs) against prostate-specific antigen (PSA) and alpha-1-antichymotrypsin (ACT) for the detection and quantification on the same tissue section. Terbium 111-118 serpin family A member 3 Homo sapiens 200-224 9697673-5 1998 Exposure of PMO to TBL or TB (1.36% glucose) resulted in a significant increase in the generation of TNFalpha (pg/2 X 10(6) PMO) compared with PD4. Terbium 19-21 tumor necrosis factor Homo sapiens 101-109 18967492-3 1999 The spectra overlap interferences from GdH, GdO, GdOH(n) (n=1-3) on Tb, Tm, Yb and Lu were eliminated by 2-thylhexylhydrogen-2-ethylhexy phosphonate (EHEHP) extraction chromatographic separation. Terbium 68-70 glutamate dehydrogenase 1 Homo sapiens 39-42 10191600-12 1999 WHO has made a great challenge with TB after the nomination of Dr Kochi to chief medical officer, TUB in 1989. Terbium 36-38 TUB bipartite transcription factor Homo sapiens 98-101 9887177-1 1999 The aim of the present study was to examine a possible involvement of leukotrienes (LTs) in lipopolysaccharide (LPS)-induced body temperature (Tb) response. Terbium 143-145 toll-like receptor 4 Mus musculus 112-115 9887177-3 1999 Intraperitoneal injection of LPS (50 microgramg/mouse) led to a decrease in Tb starting 1 h after the injection. Terbium 76-78 toll-like receptor 4 Mus musculus 29-32 9869567-9 1999 Levels of expression of the TGF-beta and interleukin-6 genes of spleen cells obtained from CAM-treated TB rats were both significantly lower than those of spleen cells from CAM-untreated TB rats. Terbium 103-105 transforming growth factor, beta 1 Rattus norvegicus 28-36 9869567-9 1999 Levels of expression of the TGF-beta and interleukin-6 genes of spleen cells obtained from CAM-treated TB rats were both significantly lower than those of spleen cells from CAM-untreated TB rats. Terbium 103-105 interleukin 6 Rattus norvegicus 41-54 9869567-9 1999 Levels of expression of the TGF-beta and interleukin-6 genes of spleen cells obtained from CAM-treated TB rats were both significantly lower than those of spleen cells from CAM-untreated TB rats. Terbium 187-189 transforming growth factor, beta 1 Rattus norvegicus 28-36 9869567-9 1999 Levels of expression of the TGF-beta and interleukin-6 genes of spleen cells obtained from CAM-treated TB rats were both significantly lower than those of spleen cells from CAM-untreated TB rats. Terbium 187-189 interleukin 6 Rattus norvegicus 41-54 9824675-0 1998 Binding of terbium and cisplatin to C13* human ovarian cancer cells using time-resolved terbium luminescence. Terbium 11-18 homeobox C13 Homo sapiens 36-39 9824675-0 1998 Binding of terbium and cisplatin to C13* human ovarian cancer cells using time-resolved terbium luminescence. Terbium 88-95 homeobox C13 Homo sapiens 36-39 9792099-2 1998 Analysis of the nuclear magnetic resonance (NMR) data for the sixth TB module from human fibrillin-1 has revealed the existence of two stable conformers that differ in the isomerization states of two proline residues. Terbium 68-70 fibrillin 1 Homo sapiens 89-100 9802428-6 1998 These results suggest that the transcription of NPY is elevated in PF rats and is increased further in anorectic TB rats. Terbium 113-115 neuropeptide Y Rattus norvegicus 48-51 9712580-1 1998 Electron-electron interactions together with Umklapp scattering resulted in a correlation gap and an insulating state for small tb. An insulator-to-metal transition was observed when tb exceeded a critical value, on the order of the correlation gap Egap. The absence of a plasma edge on the insulator side of the transition for polarization perpendicular to the chains suggests that the electrons are confined to the chains. Terbium 129-131 N-alpha-acetyltransferase 35, NatC auxiliary subunit Homo sapiens 250-254 9362480-6 1997 Analyses of MFS-causing mutations and the fibrillin-1 cell-binding RGD site provide the first clues to the surface specificity of TB domain interactions. Terbium 130-132 fibrillin 1 Homo sapiens 42-53 9932030-9 1998 COPD may often be mixed up with other obstructive diseases, especially asthma, and many doctors include also the obstructive post-TB syndromes in COPD. Terbium 130-132 COPD Homo sapiens 0-4 9932030-9 1998 COPD may often be mixed up with other obstructive diseases, especially asthma, and many doctors include also the obstructive post-TB syndromes in COPD. Terbium 130-132 COPD Homo sapiens 146-150 11364834-0 1997 Low CD4 count is predictor of TB in patients with HIV. Terbium 30-32 CD4 molecule Homo sapiens 4-7 9362480-7 1997 Modelling of a homologous TB domain from LTBP-1 (residues 1018-1080) suggests that hydrophobic contacts may play a role in its interaction with the TGF-beta1 latency-associated peptide. Terbium 26-28 latent transforming growth factor beta binding protein 1 Homo sapiens 41-47 9353367-8 1997 TB-3-4 did not permeate wild-type NMDA channels but could easily permeate channels containing an N616G mutation in the NR1 subunit. Terbium 0-2 glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis 119-122 9655153-13 1997 Following an initial drop, pHi stabilized after 4 minutes at levels of 6.96 and 6.8 after incubation in TB and TBL, respectively. Terbium 104-106 glucose-6-phosphate isomerase Homo sapiens 27-30 9417972-5 1997 Acetylcholinesterase-positive fibers predominated in area TC and pyramidal neurons in areas TA and IA and in parts of TB; a mixture of fiber and neuronal staining was found in TC/TG, TD, and IB. Terbium 118-120 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 9655153-14 1997 In comparison to the control solution, a fall of 11% and 21% in TNFalpha secretion was seen after incubation in TB for 15 and 30 minutes, respectively, and 15% and 26% after incubation in TBL. Terbium 112-114 tumor necrosis factor Homo sapiens 64-72 9432375-6 1997 beta-glucuronidase activity was higher in inactive-TB than in active-TB patients and control subjects. Terbium 51-53 glucuronidase beta Homo sapiens 0-18 9432375-6 1997 beta-glucuronidase activity was higher in inactive-TB than in active-TB patients and control subjects. Terbium 69-71 glucuronidase beta Homo sapiens 0-18 9432375-9 1997 Further, increase in the activity of beta-glucuronidase in inactive-TB patients reveals the quiescent stage of the disease. Terbium 68-70 glucuronidase beta Homo sapiens 37-55 9024798-3 1997 When C55.7 cells were transfected with either mouse ODC (M) or trypanosome ODC (Tb), intracellular putrescine content increased slightly in C55.7(Tb-ODC), compared to C55.7(M-ODC), due to the lack of response of Tb-ODC to polyamine regulation. Terbium 80-82 ornithine decarboxylase, structural 1 Mus musculus 52-55 9076974-7 1997 This alligator parvalbumin isoform is unusual in that it has an atypically high Ca2+ content (almost 3.0 mole of Ca2+ per mole of protein) following purification, a fact supported by terbium fluorescence titration experiments. Terbium 183-190 parvalbumin alpha Alligator mississippiensis 15-26 9132004-8 1997 These results clearly show that calbindin D28K binds 4 mol of calcium/mol of protein and that terbium-binding stoichiometry is similar to that of calcium. Terbium 94-101 calbindin 1 Rattus norvegicus 32-41 9024798-3 1997 When C55.7 cells were transfected with either mouse ODC (M) or trypanosome ODC (Tb), intracellular putrescine content increased slightly in C55.7(Tb-ODC), compared to C55.7(M-ODC), due to the lack of response of Tb-ODC to polyamine regulation. Terbium 80-82 ornithine decarboxylase, structural 1 Mus musculus 75-78 9024798-3 1997 When C55.7 cells were transfected with either mouse ODC (M) or trypanosome ODC (Tb), intracellular putrescine content increased slightly in C55.7(Tb-ODC), compared to C55.7(M-ODC), due to the lack of response of Tb-ODC to polyamine regulation. Terbium 80-82 ornithine decarboxylase, structural 1 Mus musculus 75-78 9024798-3 1997 When C55.7 cells were transfected with either mouse ODC (M) or trypanosome ODC (Tb), intracellular putrescine content increased slightly in C55.7(Tb-ODC), compared to C55.7(M-ODC), due to the lack of response of Tb-ODC to polyamine regulation. Terbium 80-82 ornithine decarboxylase, structural 1 Mus musculus 75-78 9024798-3 1997 When C55.7 cells were transfected with either mouse ODC (M) or trypanosome ODC (Tb), intracellular putrescine content increased slightly in C55.7(Tb-ODC), compared to C55.7(M-ODC), due to the lack of response of Tb-ODC to polyamine regulation. Terbium 80-82 ornithine decarboxylase, structural 1 Mus musculus 75-78 8869046-8 1996 Analysis of correlation allowed to identify a relation between: 1) dT and Tb [dT = Tb/[-0.305 + (0.0388)(Tb)]; P < 10(-4)]; 2) the slope of CA 125 initial regression (P) and DFS [DFS = 201.9e (-16.64*P); P < 10(-8)]; 3) P and OS [OS = 285.0e(-17.00*P); P < 10(-7)]. Terbium 74-76 mucin 16, cell surface associated Homo sapiens 143-149 15299599-1 1996 The crystal structures of three metal complexes of troponin C (TnC) have been determined and refined where the two occupied structural Ca(2+) sites in the C domain have been substituted by Mn(2+), Cd(2+) and Tb(3+). Terbium 208-210 tenascin C Homo sapiens 51-67 9132165-1 1996 The effects of lanthanide ions (Ln(3+)), La(3+), Ce(3+), Gd(3+), and Tb(3+), on the binding ability of annexin V to phospholipid vesicle were studied, and compared with that of Ca(2+). Terbium 69-71 annexin A5 Homo sapiens 103-112 8637060-8 1996 Investigation of the defense system against oxidative damage in the lung showed that superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities were all decreased after Tb administration at the higher dose. Terbium 201-203 catalase Mus musculus 113-121 8637060-8 1996 Investigation of the defense system against oxidative damage in the lung showed that superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities were all decreased after Tb administration at the higher dose. Terbium 201-203 catalase Mus musculus 123-126 8637060-10 1996 These results suggest that pulmonary lipid peroxidation may be an early and sensitive consequence of Tb exposure and that SOD, CAT, and GSH-Px might be considered as potential modulators of Tb-induced lipid peroxidation. Terbium 190-192 catalase Mus musculus 127-130 9132165-2 1996 The energy transfer following excitation at 278 nm was accompanied by a small decrease (about 3%) in the fluorescence signal (310-315 nm) of the aromatic amino acid residues, followed by strong re-emission of annexin V-bound Tb(3+) at 547 nm. Terbium 225-227 annexin A5 Homo sapiens 209-218 9132165-3 1996 The results of the titration of Tb(3+)-protein interactions using the rate dialysis method suggest that there are two high affinity metal binding sites on annexin V, to which Tb(3+) binds with an average dissociation constant, Kd, of about 2.11 x 10(-7) M. The Ln(3+) seemed to assist the anticoagulant action of annexin V because it binds more strongly to phospholipid than Ca(2+) does. Terbium 32-34 annexin A5 Homo sapiens 155-164 8992872-13 1996 Our results showed that: 1) intermittent PTH treatment of Ovx rats elicited an immediate increase of bone formation activity by the existing osteoblasts, 2) the increase of Cn-BV/TV after PTH administration resulted primarily from an increase in Tb.Th, and 3) improved mechanical strength after PTH treatment can be achieved by increases in Tb.Th without an increase in Tb.N. Terbium 246-248 parathyroid hormone Rattus norvegicus 41-44 8736106-3 1996 The activity of carnitine palmitoyltransferase (CPT) II was demonstrable in the lymphocytes of the TB group (8.2 +/- 5.6 nmol/min per mg mitochondria protein for 15 rats) and was not detected in the control, while that of CPT I was only slightly increased in the former. Terbium 99-101 carnitine palmitoyltransferase 2 Rattus norvegicus 16-55 8736106-3 1996 The activity of carnitine palmitoyltransferase (CPT) II was demonstrable in the lymphocytes of the TB group (8.2 +/- 5.6 nmol/min per mg mitochondria protein for 15 rats) and was not detected in the control, while that of CPT I was only slightly increased in the former. Terbium 99-101 carnitine palmitoyltransferase 1B Rattus norvegicus 222-227 8992872-13 1996 Our results showed that: 1) intermittent PTH treatment of Ovx rats elicited an immediate increase of bone formation activity by the existing osteoblasts, 2) the increase of Cn-BV/TV after PTH administration resulted primarily from an increase in Tb.Th, and 3) improved mechanical strength after PTH treatment can be achieved by increases in Tb.Th without an increase in Tb.N. Terbium 341-343 parathyroid hormone Rattus norvegicus 188-191 8992872-13 1996 Our results showed that: 1) intermittent PTH treatment of Ovx rats elicited an immediate increase of bone formation activity by the existing osteoblasts, 2) the increase of Cn-BV/TV after PTH administration resulted primarily from an increase in Tb.Th, and 3) improved mechanical strength after PTH treatment can be achieved by increases in Tb.Th without an increase in Tb.N. Terbium 341-343 parathyroid hormone Rattus norvegicus 188-191 8992872-13 1996 Our results showed that: 1) intermittent PTH treatment of Ovx rats elicited an immediate increase of bone formation activity by the existing osteoblasts, 2) the increase of Cn-BV/TV after PTH administration resulted primarily from an increase in Tb.Th, and 3) improved mechanical strength after PTH treatment can be achieved by increases in Tb.Th without an increase in Tb.N. Terbium 246-248 parathyroid hormone Rattus norvegicus 188-191 8992872-13 1996 Our results showed that: 1) intermittent PTH treatment of Ovx rats elicited an immediate increase of bone formation activity by the existing osteoblasts, 2) the increase of Cn-BV/TV after PTH administration resulted primarily from an increase in Tb.Th, and 3) improved mechanical strength after PTH treatment can be achieved by increases in Tb.Th without an increase in Tb.N. Terbium 246-248 parathyroid hormone Rattus norvegicus 188-191 8992872-13 1996 Our results showed that: 1) intermittent PTH treatment of Ovx rats elicited an immediate increase of bone formation activity by the existing osteoblasts, 2) the increase of Cn-BV/TV after PTH administration resulted primarily from an increase in Tb.Th, and 3) improved mechanical strength after PTH treatment can be achieved by increases in Tb.Th without an increase in Tb.N. Terbium 341-343 parathyroid hormone Rattus norvegicus 41-44 8992872-13 1996 Our results showed that: 1) intermittent PTH treatment of Ovx rats elicited an immediate increase of bone formation activity by the existing osteoblasts, 2) the increase of Cn-BV/TV after PTH administration resulted primarily from an increase in Tb.Th, and 3) improved mechanical strength after PTH treatment can be achieved by increases in Tb.Th without an increase in Tb.N. Terbium 341-343 parathyroid hormone Rattus norvegicus 188-191 8992872-13 1996 Our results showed that: 1) intermittent PTH treatment of Ovx rats elicited an immediate increase of bone formation activity by the existing osteoblasts, 2) the increase of Cn-BV/TV after PTH administration resulted primarily from an increase in Tb.Th, and 3) improved mechanical strength after PTH treatment can be achieved by increases in Tb.Th without an increase in Tb.N. Terbium 341-343 parathyroid hormone Rattus norvegicus 188-191 8992872-13 1996 Our results showed that: 1) intermittent PTH treatment of Ovx rats elicited an immediate increase of bone formation activity by the existing osteoblasts, 2) the increase of Cn-BV/TV after PTH administration resulted primarily from an increase in Tb.Th, and 3) improved mechanical strength after PTH treatment can be achieved by increases in Tb.Th without an increase in Tb.N. Terbium 341-343 parathyroid hormone Rattus norvegicus 41-44 8789106-8 1996 The Km of ATP was larger for tB than for kF, as found with fibers for Vo and their ATPase. Terbium 29-31 dynein axonemal heavy chain 8 Homo sapiens 83-89 8901228-6 1996 The serum levels of TNF-alpha in these TB patients was 2.21 +/- 1.72 pg/ml, whereas TNF-alpha was not detectable in the sera of 9 healthy control. Terbium 39-41 tumor necrosis factor Homo sapiens 20-29 8901228-8 1996 When TB patients were treated with antituberculosis drugs and clinical improvements were achieved, the elevated levels of sTNFR type I and TNF-alpha in the sera of same 5 patients measured before starting treatment showed significant decline and the serum levels of sTNFR type II showed also declined, however, the decline was statistically not significant. Terbium 5-7 tumor necrosis factor Homo sapiens 139-148 9011612-6 1996 The concurrent microinjection of 25 pg MIP-1 alpha and 25 pg MIP-1 beta into the AHPOA attenuated the effects on Tb of either cytokine alone. Terbium 113-115 C-C motif chemokine ligand 3 Rattus norvegicus 39-50 9011612-6 1996 The concurrent microinjection of 25 pg MIP-1 alpha and 25 pg MIP-1 beta into the AHPOA attenuated the effects on Tb of either cytokine alone. Terbium 113-115 C-C motif chemokine ligand 4 Rattus norvegicus 61-71 9121613-7 1996 The systemic administration of 10 mg/kg of the MAO-A inhibitor, clorgyline, also lowered Tb significantly. Terbium 89-91 monoamine oxidase A Rattus norvegicus 47-52 8844769-3 1996 The constant infusion of NPY (125 ng/h) into the perifornical hypothalamus of TB and control rats elicited increased feeding for only 2 days. Terbium 78-80 neuropeptide Y Rattus norvegicus 25-28 8844769-5 1996 Daily injection of increasing doses of NPY stimulated ad lib feeding in non-TB rats, while having no effect on TB rats. Terbium 76-78 neuropeptide Y Rattus norvegicus 39-42 8844769-7 1996 These results suggest that hypothalamic NPY feeding systems are refractory in TB rats, even before they exhibit anorexia. Terbium 78-80 neuropeptide Y Rattus norvegicus 40-43 8599813-5 1995 In the GRF the position as regards TB during the past three years is considered stabilized without apparent changes; the same applies also to the CR. Terbium 35-37 growth hormone releasing hormone Homo sapiens 7-10 8538168-5 1995 IL-1 beta enhanced wound tensile strength (WTS) in TB-irradiated mice, while TGF-beta enhanced WTS in HB-irradiated mice. Terbium 51-53 interleukin 1 beta Mus musculus 0-9 7503324-3 1995 Mice deficient in IL-1 beta had normal circadian rhythm of Tb but were less active than their control counterparts. Terbium 59-61 interleukin 1 beta Mus musculus 18-27 9223015-2 1995 In TFE both gastrin and CCK exhibited high affinities for calcium and terbium. Terbium 70-77 gastrin Homo sapiens 12-19 9223015-2 1995 In TFE both gastrin and CCK exhibited high affinities for calcium and terbium. Terbium 70-77 cholecystokinin Homo sapiens 24-27 7649174-5 1995 Tb.Ant-dATP recognizes the nucleotide site of Hsc70 as revealed by an increase in the emission anisotropy from 0.03 to 0.21 and by a change in the fluorescence-decay time from 2.52 ns to 3.75 ns. Terbium 0-2 solute carrier family 25 member 6 Homo sapiens 3-6 8558359-2 1995 The luminescence lifetime for Tb(III) measured by frequency domain fluorimetry increases from 1278 microseconds for the calmodulin complex to 1496 microsecond for the complex of calmodulin and M13, a peptide derived from the calmodulin target protein myosin light chain kinase. Terbium 30-32 calmodulin 1 Homo sapiens 120-130 8558359-2 1995 The luminescence lifetime for Tb(III) measured by frequency domain fluorimetry increases from 1278 microseconds for the calmodulin complex to 1496 microsecond for the complex of calmodulin and M13, a peptide derived from the calmodulin target protein myosin light chain kinase. Terbium 30-32 calmodulin 1 Homo sapiens 178-188 8558359-2 1995 The luminescence lifetime for Tb(III) measured by frequency domain fluorimetry increases from 1278 microseconds for the calmodulin complex to 1496 microsecond for the complex of calmodulin and M13, a peptide derived from the calmodulin target protein myosin light chain kinase. Terbium 30-32 calmodulin 1 Homo sapiens 178-188 7544380-2 1995 The effect of recombinant human IL-3 on human basophils from normal subjects was evaluated by the decrease of toluidine blue-positive basophils (TB+) and by histamine release. Terbium 145-148 interleukin 3 Homo sapiens 32-36 7544380-3 1995 IL-3 (0.001 to 100 ng) caused the decrease of TB+ without concomitant histamine release, whereas anti-IgE-induced TB+ decrease was accompanied by histamine release. Terbium 46-49 interleukin 3 Homo sapiens 0-4 7544380-4 1995 IL-3 enhanced both anti-IgE-induced TB+ decrease and histamine release. Terbium 36-39 interleukin 3 Homo sapiens 0-4 7544380-5 1995 IL-3-induced TB+ decrease was dose- and Ca2+-dependent and related to the time of incubation (detectable after an incubation of 5 min and maximal after incubation of 2 h). Terbium 13-16 interleukin 3 Homo sapiens 0-4 7544380-11 1995 These results indicate that: 1) IL-3 can induce TB+ decrease without concomitant histamine release, 2) basophils from normal subjects can release histamine on challenge with IL-3 once the inhibitory effect of Na+ is removed, and 3) Na+ and K+ down-regulate IL-3 as well as anti-IgE-induced histamine release. Terbium 48-51 interleukin 3 Homo sapiens 32-36 7544380-11 1995 These results indicate that: 1) IL-3 can induce TB+ decrease without concomitant histamine release, 2) basophils from normal subjects can release histamine on challenge with IL-3 once the inhibitory effect of Na+ is removed, and 3) Na+ and K+ down-regulate IL-3 as well as anti-IgE-induced histamine release. Terbium 48-51 interleukin 3 Homo sapiens 174-178 7544380-11 1995 These results indicate that: 1) IL-3 can induce TB+ decrease without concomitant histamine release, 2) basophils from normal subjects can release histamine on challenge with IL-3 once the inhibitory effect of Na+ is removed, and 3) Na+ and K+ down-regulate IL-3 as well as anti-IgE-induced histamine release. Terbium 48-51 interleukin 3 Homo sapiens 174-178 8748250-9 1995 Eight of the 13 TB rats had detectable concentrations of CSF IL-1 alpha; the mean CSF IL-1 alpha concentration for TB rats was 73.2 +/- 17.3 pg/ml. Terbium 16-18 interleukin 1 alpha Rattus norvegicus 61-71 8748250-12 1995 Data suggest a link between CSF IL-1 alpha and food intake in anorectic TB rats. Terbium 72-74 interleukin 1 alpha Rattus norvegicus 32-42 7649174-5 1995 Tb.Ant-dATP recognizes the nucleotide site of Hsc70 as revealed by an increase in the emission anisotropy from 0.03 to 0.21 and by a change in the fluorescence-decay time from 2.52 ns to 3.75 ns. Terbium 0-2 heat shock protein family A (Hsp70) member 8 Homo sapiens 46-51 7631899-6 1995 In addition, a human recombinant TNF-alpha given intraperitoneally abolished fever and prolonged the fall of Tb in mice after LPS. Terbium 109-111 tumor necrosis factor Homo sapiens 33-42 7631899-7 1995 We conclude that the reduction of Tb soon after injection of LPS in mice is dependent on TNF-alpha. Terbium 34-36 tumor necrosis factor Mus musculus 89-98 8067285-1 1994 The efficacy of NPY to elicit feeding in TB rats was reduced prior to the onset of overt anorexia, with the feeding response decreasing further as anorexia developed. Terbium 41-43 neuropeptide Y Rattus norvegicus 16-19 7616410-13 1995 DY/NT reduced Tb dose dependently but the effect did not differ significantly from NT alone. Terbium 14-16 neurotensin Rattus norvegicus 3-5 8061214-0 1994 Changes in the profile structure of the sarcoplasmic reticulum membrane induced by phosphorylation of the Ca2+ ATPase enzyme in the presence of terbium: a time-resolved x-ray diffraction study. Terbium 144-151 dynein axonemal heavy chain 8 Homo sapiens 111-117 8061214-3 1994 The results from the time-resolved, nonresonance x-ray diffraction work reported in this paper are consistent with the enzyme phosphorylation experiments; they indicate that the changes in the profile structure of the SR membrane induced by terbium-activated phosphorylation of the ATPase enzyme are persistent over the much longer lifetime of the phosphorylated enzyme and are qualitatively similar to the changes induced by calcium-activated phosphorylation, but smaller in magnitude. Terbium 241-248 dynein axonemal heavy chain 8 Homo sapiens 282-288 8061215-0 1994 Changes in the relative occupancy of metal-binding sites in the profile structure of the sarcoplasmic reticulum membrane induced by phosphorylation of the Ca2+ATPase enzyme in the presence of terbium: a time-resolved, resonance x-ray diffraction study. Terbium 192-199 dynein axonemal heavy chain 8 Homo sapiens 159-165 7552623-5 1995 Liver GCS activity (nanomolar per hour per milligram protein) in TB rats (106.6 +/- 37.7) was increased (p < 0.01) compared with CTL rats (57.5 +/- 12.3) and correlated positively with tumor burden (R = 0.77). Terbium 65-67 glutamate-cysteine ligase, catalytic subunit Rattus norvegicus 6-9 7552623-6 1995 Muscle GGTP was decreased (p = 0.001) in TB rats (1.7 +/- 1.1) compared with controls (6.8 +/- 1.1). Terbium 41-43 gamma-glutamyltransferase 1 Rattus norvegicus 7-11 7605940-3 1995 Eight of the 13 anorectic TB rats had detectable CSF IL-1 alpha; no CSF IL-1 alpha was detected in controls. Terbium 26-28 interleukin 1 alpha Rattus norvegicus 53-63 7605940-4 1995 In anorectic TB rats a negative correlation existed between CSF IL-1 alpha and food intake and a positive correlation between CSF IL-1 alpha and tumor weight. Terbium 13-15 interleukin 1 alpha Rattus norvegicus 64-74 7605940-4 1995 In anorectic TB rats a negative correlation existed between CSF IL-1 alpha and food intake and a positive correlation between CSF IL-1 alpha and tumor weight. Terbium 13-15 interleukin 1 alpha Rattus norvegicus 130-140 7739912-7 1995 Activity of ornithine decarboxylase was increased in the NTB-TPN group but was not altered significantly in either TB group. Terbium 58-60 ornithine decarboxylase 1 Rattus norvegicus 12-35 7947682-13 1994 Finally, terbium derivatives of Fbp and human transferrin yield virtually identical luminescence excitation spectra, implying a highly similar binding site environment. Terbium 9-16 folate receptor beta Homo sapiens 32-35 7947682-13 1994 Finally, terbium derivatives of Fbp and human transferrin yield virtually identical luminescence excitation spectra, implying a highly similar binding site environment. Terbium 9-16 transferrin Homo sapiens 46-57 7807590-5 1994 MIP-1 beta in a dose of 25 pg evoked an intense fever characterized by a short latency, a mean maximum rise in Tb of 2.4 +/- 0.21 degrees C reached by 3.7 +/- 0.42 hr, and a duration exceeding 6.5 hr. Terbium 111-113 C-C motif chemokine ligand 4 Rattus norvegicus 0-10 7807590-6 1994 Injected into homologous sites in the AH/POA, IL-6 induced a dose dependent fever of similar latency and a mean maximal increase in Tb of 1.2 +/- 0.25 degrees C, 1.8 +/- 0.15 degrees C, and 2.1 +/- 0.22 degrees C and duration of 6.2 +/- 1.28 hr, 6.7 +/- 0.49 hr, and 6.8 +/- 0.65 hr when given in doses of 25, 50, and 100 ng, respectively. Terbium 132-134 interleukin 6 Rattus norvegicus 46-50 7914137-0 1994 Manifestations of TB to CD4 cell counts. Terbium 18-20 CD4 molecule Homo sapiens 24-27 8049142-4 1994 These results suggest that the androgen receptor mRNA determined might encode TBS and that testosterone may stimulate the metabolic rate of TBS, or inhibit the translation rate of androgen receptor mRNA to TBS. Terbium 78-81 androgen receptor Homo sapiens 31-48 8067285-2 1994 Hypothalamic concentration of NPY was reduced in TB rats, with the magnitude of the decrease paralleling the degree of anorexia. Terbium 49-51 neuropeptide Y Rattus norvegicus 30-33 8067285-5 1994 These results suggest that NPY feeding systems are abnormal in TB rats and that hyperammonemia may be of primary importance in this dysfunction. Terbium 63-65 neuropeptide Y Rattus norvegicus 27-30 7999418-5 1994 Increased levels of t-PA were found in TB, but not in CF, indicating that t-PA is released by the tumour vasculature, but not by the tumour tissue. Terbium 39-41 plasminogen activator, tissue type Homo sapiens 20-24 7999418-5 1994 Increased levels of t-PA were found in TB, but not in CF, indicating that t-PA is released by the tumour vasculature, but not by the tumour tissue. Terbium 39-41 plasminogen activator, tissue type Homo sapiens 74-78 7920280-5 1994 Tb contacts showed depressed granulocyte metabolic activity as measured by CL response to chemostatic peptide N-FORMYL-MET-LEU-PHE (FMLP) in comparison with control subjects. Terbium 0-2 formyl peptide receptor 1 Homo sapiens 110-130 7881860-6 1994 The authors recommend to control the level of yttrium, terbium and lutetium fluorides in the air of workplace through the MACs for the fluorides at 2.5 mg/cu m (maximal single concentration) and 0.5 mg/cu m (average shift concentration), the level of ytterbium fluoride as moderate fibrogenic dust at 6 mg/cu m. Terbium 55-62 myristoylated alanine rich protein kinase C substrate Rattus norvegicus 122-126 7920280-5 1994 Tb contacts showed depressed granulocyte metabolic activity as measured by CL response to chemostatic peptide N-FORMYL-MET-LEU-PHE (FMLP) in comparison with control subjects. Terbium 0-2 formyl peptide receptor 1 Homo sapiens 132-136 8456066-2 1993 This method was based on competitive displacement of DPA from binding to terbium by stronger chelating groups such as diethylenetriaminepentaacetic acid (DTPA), EDTA, nitrilotriacetic acid (NTA), DTPA-conjugated bovine serum albumin (BSA-DTPA), or DTPA-conjugated immunoglobulin G (IgG-DTPA), resulting in a significant reduction in terbium fluorescence. Terbium 73-80 albumin Homo sapiens 219-232 8510794-5 1993 MIP-1 alpha micro-injected similarly evoked a biphasic fever, with the Tb declining transiently at the 30 min point > or = 0.4 degrees C lower than the congruent rises in Tb evoked by doublet MIP-1 or MIP-1 beta. Terbium 71-73 C-C motif chemokine ligand 3 Rattus norvegicus 0-11 8510794-5 1993 MIP-1 alpha micro-injected similarly evoked a biphasic fever, with the Tb declining transiently at the 30 min point > or = 0.4 degrees C lower than the congruent rises in Tb evoked by doublet MIP-1 or MIP-1 beta. Terbium 71-73 zinc finger protein 667 Rattus norvegicus 0-5 8510794-5 1993 MIP-1 alpha micro-injected similarly evoked a biphasic fever, with the Tb declining transiently at the 30 min point > or = 0.4 degrees C lower than the congruent rises in Tb evoked by doublet MIP-1 or MIP-1 beta. Terbium 174-176 C-C motif chemokine ligand 3 Rattus norvegicus 0-11 8510794-5 1993 MIP-1 alpha micro-injected similarly evoked a biphasic fever, with the Tb declining transiently at the 30 min point > or = 0.4 degrees C lower than the congruent rises in Tb evoked by doublet MIP-1 or MIP-1 beta. Terbium 174-176 zinc finger protein 667 Rattus norvegicus 0-5 8510794-6 1993 The secondary rise in Tb induced by MIP-1 alpha had a latency of 1.5-2.0 hrs and reached a maximum of 1.56 +/- 0.16 degrees C. Although all three cytokines significantly attenuated the rats" mean intake of food during the 24 hr interval after their micro-injection into the AH/POA, doublet MIP-1 exerted the most potent anorexic effect in comparison to that of the saline control rats. Terbium 22-24 C-C motif chemokine ligand 3 Rattus norvegicus 36-47 8510794-6 1993 The secondary rise in Tb induced by MIP-1 alpha had a latency of 1.5-2.0 hrs and reached a maximum of 1.56 +/- 0.16 degrees C. Although all three cytokines significantly attenuated the rats" mean intake of food during the 24 hr interval after their micro-injection into the AH/POA, doublet MIP-1 exerted the most potent anorexic effect in comparison to that of the saline control rats. Terbium 22-24 zinc finger protein 667 Rattus norvegicus 36-41 2277198-4 1990 Patients with the meningoencephalitis syndrome and CSF findings of low glucose levels, elevated protein levels, and pleocytosis should be treated immediately if there is evidence of TB elsewhere in the body, or if prompt evaluation fails to establish an alternative diagnosis. Terbium 182-184 colony stimulating factor 2 Homo sapiens 51-54 8319099-6 1993 The bilateral microinjection of MIP-1 in a dose of 14 pg per 0.5 microliters into the AH/POA caused a biphasic elevation in Tb to 0.9 +/- 0.2 degrees C within 1.0 h, which reached 1.5 +/- 0.2 degrees C within 3.0 h, and persisted for over 6.0 h. An identical injection of MIP-1 into the VSA increased Tb biphasically to 0.1 +/- 0.1 degrees C within 1.0 h and to 0.8 +/- 0.3 degrees C within 3.0 h. The infusion into the third ventricle of 80 micrograms/10 microliters of the inhibitor of protein synthesis, anisomycin, either 10 or 30 min before the microinjection of MIP-1 into the AH/POA, attenuated significantly the rise in Tb for 1.0 to 3.0 h or 2.5 to 3.0 h, respectively. Terbium 124-126 zinc finger protein 667 Rattus norvegicus 32-37 8319099-6 1993 The bilateral microinjection of MIP-1 in a dose of 14 pg per 0.5 microliters into the AH/POA caused a biphasic elevation in Tb to 0.9 +/- 0.2 degrees C within 1.0 h, which reached 1.5 +/- 0.2 degrees C within 3.0 h, and persisted for over 6.0 h. An identical injection of MIP-1 into the VSA increased Tb biphasically to 0.1 +/- 0.1 degrees C within 1.0 h and to 0.8 +/- 0.3 degrees C within 3.0 h. The infusion into the third ventricle of 80 micrograms/10 microliters of the inhibitor of protein synthesis, anisomycin, either 10 or 30 min before the microinjection of MIP-1 into the AH/POA, attenuated significantly the rise in Tb for 1.0 to 3.0 h or 2.5 to 3.0 h, respectively. Terbium 301-303 zinc finger protein 667 Rattus norvegicus 32-37 8319099-6 1993 The bilateral microinjection of MIP-1 in a dose of 14 pg per 0.5 microliters into the AH/POA caused a biphasic elevation in Tb to 0.9 +/- 0.2 degrees C within 1.0 h, which reached 1.5 +/- 0.2 degrees C within 3.0 h, and persisted for over 6.0 h. An identical injection of MIP-1 into the VSA increased Tb biphasically to 0.1 +/- 0.1 degrees C within 1.0 h and to 0.8 +/- 0.3 degrees C within 3.0 h. The infusion into the third ventricle of 80 micrograms/10 microliters of the inhibitor of protein synthesis, anisomycin, either 10 or 30 min before the microinjection of MIP-1 into the AH/POA, attenuated significantly the rise in Tb for 1.0 to 3.0 h or 2.5 to 3.0 h, respectively. Terbium 301-303 zinc finger protein 667 Rattus norvegicus 32-37 8417277-2 1993 Inhibition studies were performed with tolbutamide and sulfaphenazole (respectively the prototype substrate and a selective inhibitor of cytochrome P450TB--CYP2C subfamily), and with phenytoin and (+/-)-warfarin, other proposed substrates of P450TB. Terbium 152-154 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 156-161 1643036-0 1992 Europium(III) luminescence and tyrosine to terbium(III) energy-transfer studies of invertebrate (octopus) calmodulin. Terbium 43-50 calmodulin Bos taurus 106-116 1317483-8 1992 Interleukin-4 administered to cultured cells from TB mice enhanced O2-, as well as MLR and CTL (P less than 0.01), and decreased TNF release but did not alter PM phi TNF-independent anti-tumor responses (P815). Terbium 50-52 interleukin 4 Mus musculus 0-13 1317483-8 1992 Interleukin-4 administered to cultured cells from TB mice enhanced O2-, as well as MLR and CTL (P less than 0.01), and decreased TNF release but did not alter PM phi TNF-independent anti-tumor responses (P815). Terbium 50-52 tumor necrosis factor Mus musculus 129-132 1317483-10 1992 These findings indicate the therapeutic potential of IL-4 in the TB host which may function through downregulation of TNF production while potentiating certain T cell-dependent and independent anti-tumor immune mechanisms. Terbium 65-67 interleukin 4 Mus musculus 53-57 1317483-10 1992 These findings indicate the therapeutic potential of IL-4 in the TB host which may function through downregulation of TNF production while potentiating certain T cell-dependent and independent anti-tumor immune mechanisms. Terbium 65-67 tumor necrosis factor Mus musculus 118-121 1373040-3 1992 In the tumor-bearing (TB) population, IGF-I-treated groups showed a dose-dependent increase in host weight gain (P less than 0.05), final carcass weight (P less than 0.05), and gastrocnemius muscle weights (P less than 0.05) and protein contents (0.50 +/- 0.02, 0.40 +/- 0.01, and 0.52 +/- 0.03 g/100 g host wt, for non-TB saline, TB saline, and TB 400 mg IGF-I groups, respectively; P less than 0.01, IGF-I vs. saline). Terbium 22-24 insulin-like growth factor 1 Rattus norvegicus 38-43 1373040-3 1992 In the tumor-bearing (TB) population, IGF-I-treated groups showed a dose-dependent increase in host weight gain (P less than 0.05), final carcass weight (P less than 0.05), and gastrocnemius muscle weights (P less than 0.05) and protein contents (0.50 +/- 0.02, 0.40 +/- 0.01, and 0.52 +/- 0.03 g/100 g host wt, for non-TB saline, TB saline, and TB 400 mg IGF-I groups, respectively; P less than 0.01, IGF-I vs. saline). Terbium 320-322 insulin-like growth factor 1 Rattus norvegicus 38-43 1498521-4 1992 Lyt-2+ cells in the spleen increased transiently (7 days) in tumor-bearing (TB) mice and returned to normal levels by 14 days TB. Terbium 76-78 CD8 antigen, alpha chain Mus musculus 0-5 1498521-8 1992 The numbers of Lyt-2+ cells in both the spleen and BM of 7 days indomethacin-treated TB mice were reduced relative to those of untreated TB mice. Terbium 85-87 CD8 antigen, alpha chain Mus musculus 15-20 1901758-4 1991 TB rats treated with an antisera to recombinant murine TNF, which was 100% protective when given to NTB rats 6 h before a lethal endotoxin challenge, did not differ significantly from TB rats treated with control antibody with respect to food intake, body weight, survival, or tumor size. Terbium 0-2 tumor necrosis factor Mus musculus 55-58 1901758-4 1991 TB rats treated with an antisera to recombinant murine TNF, which was 100% protective when given to NTB rats 6 h before a lethal endotoxin challenge, did not differ significantly from TB rats treated with control antibody with respect to food intake, body weight, survival, or tumor size. Terbium 101-103 tumor necrosis factor Mus musculus 55-58 1863267-0 1991 Effect of phosphorylation of calmodulin on calcium binding affinity as estimated by terbium fluorescence. Terbium 84-91 calmodulin 1 Homo sapiens 29-39 1863267-1 1991 The effect of phosphorylation of calmodulin by casein kinase 2 on the calcium binding of the former was studied by measurement of terbium fluorescence. Terbium 130-137 calmodulin 1 Homo sapiens 33-43 1863267-3 1991 The terbium fluorescence of phosphorylated calmodulin increased at a lower concentration of Tb3+ than that of non-phosphorylated calmodulin, indicating that Tb3+ binding affinity of calmodulin was increased by phosphorylation. Terbium 4-11 calmodulin 1 Homo sapiens 43-53 8129478-18 1993 In a small recent prospective study 4 out of 10 HIV+ persons with no evidence for TB yielded a positive result for the ELISA-P32. Terbium 82-84 CD8a molecule Homo sapiens 125-128 1294780-5 1992 The results were as follows: (1) The production of IL-1 beta, TNF alpha and IL-6 in TB patients was significantly higher than that observed in the healthy control subjects. Terbium 84-86 interleukin 1 beta Homo sapiens 51-60 1294780-5 1992 The results were as follows: (1) The production of IL-1 beta, TNF alpha and IL-6 in TB patients was significantly higher than that observed in the healthy control subjects. Terbium 84-86 tumor necrosis factor Homo sapiens 62-71 1294780-5 1992 The results were as follows: (1) The production of IL-1 beta, TNF alpha and IL-6 in TB patients was significantly higher than that observed in the healthy control subjects. Terbium 84-86 interleukin 6 Homo sapiens 76-80 1294780-6 1992 (2) The production of IL-1 beta, TNF alpha and IL-6 in TB+DM patients was significantly lower than that observed in the TB patients. Terbium 55-57 interleukin 1 beta Homo sapiens 22-31 1294780-6 1992 (2) The production of IL-1 beta, TNF alpha and IL-6 in TB+DM patients was significantly lower than that observed in the TB patients. Terbium 55-57 tumor necrosis factor Homo sapiens 33-42 1294780-6 1992 (2) The production of IL-1 beta, TNF alpha and IL-6 in TB+DM patients was significantly lower than that observed in the TB patients. Terbium 55-57 interleukin 6 Homo sapiens 47-51 1294780-7 1992 (3) The production of IL-1 beta and TNF alpha in TB+DM patients with poor control was significantly lower than that observed in the patients with good control. Terbium 49-51 interleukin 1 beta Homo sapiens 22-31 1294780-7 1992 (3) The production of IL-1 beta and TNF alpha in TB+DM patients with poor control was significantly lower than that observed in the patients with good control. Terbium 49-51 tumor necrosis factor Homo sapiens 36-45 1294780-8 1992 (4) The TNF alpha production had a significant inverse correlation to HbA1c in the TB+DM patients. Terbium 83-85 tumor necrosis factor Homo sapiens 8-17 1960917-4 1991 On the first issue of the problem, how to treat the refractory TB, Dr. Ikeda reported that chronic, bacilli-positive cases with long duration of chemotherapy showed poor prognosis, often fatal because they were usually resistant to other drugs, too, in addition to INH and RFP, whereas some cases in which no prior chemotherapy was conducted responded to ordinary regimen including INH and RFP. Terbium 63-65 tripartite motif containing 27 Homo sapiens 273-276 1960917-4 1991 On the first issue of the problem, how to treat the refractory TB, Dr. Ikeda reported that chronic, bacilli-positive cases with long duration of chemotherapy showed poor prognosis, often fatal because they were usually resistant to other drugs, too, in addition to INH and RFP, whereas some cases in which no prior chemotherapy was conducted responded to ordinary regimen including INH and RFP. Terbium 63-65 tripartite motif containing 27 Homo sapiens 390-393 1960917-13 1991 However, treatment of drug-resistant cases at home sometimes led to the development of new TB cases among the family, that is infection in children and grandchildren whose bacilli were also found resistant to INH and RFP. Terbium 91-93 tripartite motif containing 27 Homo sapiens 217-220 1654822-0 1991 The binding of terbium ions to gelsolin reveals two classes of metal ion binding sites. Terbium 15-22 gelsolin Homo sapiens 31-39 33943031-5 2021 Pretreatment screening tests had been performed using the T-SPOT.TB assay, which quantifies the number of interferon-gamma-releasing T cells (as immunospots) in response to phytohemagglutinin and tuberculosis-specific antigen stimulation. Terbium 65-67 interferon gamma Homo sapiens 106-122 2354441-8 1990 Following treatment, TB rats that had been treated with rTNF ate significantly more and lost less weight than TB rats that had been treated with saline (P less than 0.00001). Terbium 21-23 tumor necrosis factor Rattus norvegicus 56-60 2354441-9 1990 rTNF treatment of TB rats also demonstrated antineoplastic activity, as estimated tumor weight of tumors from rats treated with rTNF were significantly less than controls (P = 0.003). Terbium 18-20 tumor necrosis factor Rattus norvegicus 0-4 2354441-9 1990 rTNF treatment of TB rats also demonstrated antineoplastic activity, as estimated tumor weight of tumors from rats treated with rTNF were significantly less than controls (P = 0.003). Terbium 18-20 tumor necrosis factor Rattus norvegicus 128-132 2354441-10 1990 The anticachexia and antineoplastic effects of rTNF resulted in prolonged survival of TB rats treated with rTNF compared to control TB rats (P = 0.015). Terbium 86-88 tumor necrosis factor Rattus norvegicus 47-51 2354441-10 1990 The anticachexia and antineoplastic effects of rTNF resulted in prolonged survival of TB rats treated with rTNF compared to control TB rats (P = 0.015). Terbium 86-88 tumor necrosis factor Rattus norvegicus 107-111 2354441-10 1990 The anticachexia and antineoplastic effects of rTNF resulted in prolonged survival of TB rats treated with rTNF compared to control TB rats (P = 0.015). Terbium 132-134 tumor necrosis factor Rattus norvegicus 47-51 2354441-14 1990 Survival of TB rats treated with rTNF was again significantly increased in a dose-dependent manner (P = 0.006). Terbium 12-14 tumor necrosis factor Rattus norvegicus 33-37 2354441-15 1990 Repeated administration of low doses of rTNF to TB rats induces mild reduction in tumor growth, tolerance to the cachectic effects of rTNF that results in tolerance to the cachectic effects of tumor, and prolongation of survival. Terbium 48-50 tumor necrosis factor Rattus norvegicus 40-44 2354441-15 1990 Repeated administration of low doses of rTNF to TB rats induces mild reduction in tumor growth, tolerance to the cachectic effects of rTNF that results in tolerance to the cachectic effects of tumor, and prolongation of survival. Terbium 48-50 tumor necrosis factor Rattus norvegicus 134-138 2317813-16 1990 to TNF-pretreated TB mice did not improve therapeutic efficacy. Terbium 18-20 tumor necrosis factor Mus musculus 3-6 2317813-17 1990 In mice bearing the MCA-106 tumor the most efficacious treatment responses were seen in animals that were previously naive to TNF, and treatment toxicity (lethality) correlated directly with antitumor efficacy such that larger treatment doses of TNF in tolerant mice resulted in similar antitumor effects as smaller treatment doses in control TB mice. Terbium 343-345 tumor necrosis factor Mus musculus 246-249 2317813-20 1990 The results suggest that TNF tolerance occurs in TB mice and reduces the toxicity as well as the therapeutic efficacy of TNF. Terbium 49-51 tumor necrosis factor Mus musculus 25-28 2317813-20 1990 The results suggest that TNF tolerance occurs in TB mice and reduces the toxicity as well as the therapeutic efficacy of TNF. Terbium 49-51 tumor necrosis factor Mus musculus 121-124 2160874-10 1990 The contents of CRH and AVP in stalk-median eminence extracts of TB nude mice was significantly lower than that of C nude mice. Terbium 65-67 corticotropin releasing hormone Mus musculus 16-19 1702755-6 1990 While there was an increase in the concentrations of transferrin in patients with pulmonary and abdominal TB, there was a significant decrease in those with TB meningitis; alpha 2-macroglobulin did not appear to function as an acute phase reactant in any of the 3 groups. Terbium 106-108 transferrin Homo sapiens 53-64 33818004-9 2021 In the TB group, BMP-2, P-SMAD1/5, RUNX2 and OPG levels were increased in bone tissue (P < 0.01), RANKL levels were decreased (P < 0.01), and the bone microstructure and biomechanical strength were improved. Terbium 7-9 bone morphogenetic protein 2 Rattus norvegicus 17-22 33818004-9 2021 In the TB group, BMP-2, P-SMAD1/5, RUNX2 and OPG levels were increased in bone tissue (P < 0.01), RANKL levels were decreased (P < 0.01), and the bone microstructure and biomechanical strength were improved. Terbium 7-9 RUNX family transcription factor 2 Rattus norvegicus 35-40 33818004-9 2021 In the TB group, BMP-2, P-SMAD1/5, RUNX2 and OPG levels were increased in bone tissue (P < 0.01), RANKL levels were decreased (P < 0.01), and the bone microstructure and biomechanical strength were improved. Terbium 7-9 TNF receptor superfamily member 11B Rattus norvegicus 45-48 33818004-9 2021 In the TB group, BMP-2, P-SMAD1/5, RUNX2 and OPG levels were increased in bone tissue (P < 0.01), RANKL levels were decreased (P < 0.01), and the bone microstructure and biomechanical strength were improved. Terbium 7-9 TNF superfamily member 11 Rattus norvegicus 98-103 33793834-9 2021 Furthermore, we found that gallic acid treatment inhibited NF-kappaB/TLR-4 axis upregulated by the anti-TB drugs. Terbium 104-106 toll-like receptor 4 Rattus norvegicus 69-74 24011630-9 2013 Hence we conclude that IFN-gamma or TNF-alpha response to these ESAT-6 peptides has the potential to differentiate between active and latent TB in our population. Terbium 141-143 interferon gamma Homo sapiens 23-32 24011630-9 2013 Hence we conclude that IFN-gamma or TNF-alpha response to these ESAT-6 peptides has the potential to differentiate between active and latent TB in our population. Terbium 141-143 tumor necrosis factor Homo sapiens 36-45 34705574-11 2022 However, the ability of the GeneXpert MTB/RIF to provide rapid TB diagnosis is not dependent on sputum quality. Terbium 63-65 ras homolog family member F, filopodia associated Homo sapiens 42-45 34284646-4 2022 OBJECTIVE: The objective was to examine the effect of DN on muscle stiffness and motoneuron excitability of a latent medial MTrP (nodule and TB) of the soleus muscle in non-injured subjects. Terbium 141-143 lysosomal protein transmembrane 4 alpha Homo sapiens 124-128 34899731-6 2021 Lung macrophages and blood monocytes from M.tb-infected TCRbeta-/- mice showed upregulated expression of cell surface activation markers and also showed higher mRNA expression of inflammation-associated chemokines and matrix metalloproteases responsible for tissue damage. Terbium 44-46 T cell receptor alpha chain Mus musculus 56-63 34419792-1 2022 In this work, we demonstrate a novel solid-state electrochemiluminescence (ECL) sensor based on the Ru(bpy)32+@terbium-guanosine monophosphate infinite coordination polymer network ((Ru(bpy)32+@Tb-GMP ICPn). Terbium 194-196 5'-nucleotidase, cytosolic II Homo sapiens 197-200 34358784-0 2022 ZIF-8@GMP-Tb nanocomplex for ratiometric fluorescent detection of alkaline phosphatase activity. Terbium 10-12 5'-nucleotidase, cytosolic II Homo sapiens 0-9 34358784-0 2022 ZIF-8@GMP-Tb nanocomplex for ratiometric fluorescent detection of alkaline phosphatase activity. Terbium 10-12 alkaline phosphatase, placental Homo sapiens 66-86 34358784-2 2022 In this work, guanosine monophosphate (GMP), terbium ion (Tb3+) and zeolitic imidazolate framework-8 (ZIF-8) are self-assembled to form a ZIF-8@GMP-Tb nanocomplex, which can be utilized as a ratiometric fluorescent probe to monitor alkaline phosphatase (ALP) activity. Terbium 148-150 alkaline phosphatase, placental Homo sapiens 232-252 34358784-2 2022 In this work, guanosine monophosphate (GMP), terbium ion (Tb3+) and zeolitic imidazolate framework-8 (ZIF-8) are self-assembled to form a ZIF-8@GMP-Tb nanocomplex, which can be utilized as a ratiometric fluorescent probe to monitor alkaline phosphatase (ALP) activity. Terbium 148-150 alkaline phosphatase, placental Homo sapiens 254-257 34933240-4 2022 Our results demonstrated that LTBI individuals with SARS-CoV-2 seropositivity (LTBI+/IgG +) were associated with increased levels of unstimulated and TB-antigen stimulated IFNgamma, IL-2, TNFalpha, IL-17, IL-1beta, IL-6, IL-12, IL-4, CXCL1, CXCL9 and CXCL10 when compared to those without seropositivity (LTBI+/IgG-). Terbium 150-152 interferon gamma Homo sapiens 172-180 34736839-7 2022 RC ground TB had greater moisture fat-free than CN. Terbium 10-12 regucalcin Bos taurus 0-2 34736839-10 2022 RC ground TB had greater oxygen consumption and lower thiobarbituric acid reactive substances compared to CN. Terbium 10-12 regucalcin Bos taurus 0-2 34396977-4 2022 Specifically, Tb(III) binds to its receptor (FASCICLIN-like arabinogalactan protein 17 (FLA17)) on the plasma membrane of leaf cells and then docks to an intracellular adaptor protein (adaptor protein 2 (AP2)) to form ternary complex (Tb(III)-FLA17-AP2), which finally initiates CME pathway in leaf cells. Terbium 14-16 transcription factor AP-2 alpha Homo sapiens 185-202 34396977-4 2022 Specifically, Tb(III) binds to its receptor (FASCICLIN-like arabinogalactan protein 17 (FLA17)) on the plasma membrane of leaf cells and then docks to an intracellular adaptor protein (adaptor protein 2 (AP2)) to form ternary complex (Tb(III)-FLA17-AP2), which finally initiates CME pathway in leaf cells. Terbium 14-16 transcription factor AP-2 alpha Homo sapiens 204-207 34396977-4 2022 Specifically, Tb(III) binds to its receptor (FASCICLIN-like arabinogalactan protein 17 (FLA17)) on the plasma membrane of leaf cells and then docks to an intracellular adaptor protein (adaptor protein 2 (AP2)) to form ternary complex (Tb(III)-FLA17-AP2), which finally initiates CME pathway in leaf cells. Terbium 14-16 transcription factor AP-2 alpha Homo sapiens 249-252 34396977-4 2022 Specifically, Tb(III) binds to its receptor (FASCICLIN-like arabinogalactan protein 17 (FLA17)) on the plasma membrane of leaf cells and then docks to an intracellular adaptor protein (adaptor protein 2 (AP2)) to form ternary complex (Tb(III)-FLA17-AP2), which finally initiates CME pathway in leaf cells. Terbium 235-237 transcription factor AP-2 alpha Homo sapiens 185-202 34396977-4 2022 Specifically, Tb(III) binds to its receptor (FASCICLIN-like arabinogalactan protein 17 (FLA17)) on the plasma membrane of leaf cells and then docks to an intracellular adaptor protein (adaptor protein 2 (AP2)) to form ternary complex (Tb(III)-FLA17-AP2), which finally initiates CME pathway in leaf cells. Terbium 235-237 transcription factor AP-2 alpha Homo sapiens 204-207 34396977-4 2022 Specifically, Tb(III) binds to its receptor (FASCICLIN-like arabinogalactan protein 17 (FLA17)) on the plasma membrane of leaf cells and then docks to an intracellular adaptor protein (adaptor protein 2 (AP2)) to form ternary complex (Tb(III)-FLA17-AP2), which finally initiates CME pathway in leaf cells. Terbium 235-237 transcription factor AP-2 alpha Homo sapiens 249-252 34922263-13 2022 The irGEP analysis implicated M2-type macrophages, angiogenesis and transforming growth factor-beta as well as protumourigenic signalling pathways in ICI resistance conferred by a high TB. Terbium 185-187 tumor necrosis factor Homo sapiens 68-99 34919497-8 2021 CONCLUSIONS: Intraocular TB granulomas have high levels of VEGF-A. Terbium 25-27 vascular endothelial growth factor A Homo sapiens 59-65 34717654-6 2021 The targeted fluorescence imaging of TB/PTX@RTK micelles and the synergistic anti-tumor efficacy of TB/PTX@RTK micelles-mediated chemo-PDT combined with anti-PD-L1 were assessed both in vitro and in vivo. Terbium 37-39 CD274 molecule Homo sapiens 158-163 34887853-7 2021 Six months of TB therapy significantly decreased levels of major neutrophil-derived pro-inflammatory mediators: MMP1 (p = 4.90E-12 and p = 2.20E-07), MMP8 (p = 3.40E-14 and p = 1.30E-05) and MMP9 (p = 1.60E-04 and p = 1.50E-03) in plasma and sputum, respectively. Terbium 14-16 matrix metallopeptidase 1 Homo sapiens 112-116 34887853-7 2021 Six months of TB therapy significantly decreased levels of major neutrophil-derived pro-inflammatory mediators: MMP1 (p = 4.90E-12 and p = 2.20E-07), MMP8 (p = 3.40E-14 and p = 1.30E-05) and MMP9 (p = 1.60E-04 and p = 1.50E-03) in plasma and sputum, respectively. Terbium 14-16 matrix metallopeptidase 8 Homo sapiens 150-154 34887853-7 2021 Six months of TB therapy significantly decreased levels of major neutrophil-derived pro-inflammatory mediators: MMP1 (p = 4.90E-12 and p = 2.20E-07), MMP8 (p = 3.40E-14 and p = 1.30E-05) and MMP9 (p = 1.60E-04 and p = 1.50E-03) in plasma and sputum, respectively. Terbium 14-16 matrix metallopeptidase 9 Homo sapiens 191-195 34835204-4 2021 Recently we described the protective efficacy of new mucosal TB vaccine candidate based on recombinant attenuated influenza vector (Flu/THSP) co-expressing TB10.4 and HspX proteins of M.tb within an NS1 influenza protein open reading frame. Terbium 61-63 thymosin, beta 10 Mus musculus 156-160 34815862-4 2021 TNF-alpha and CRP has a major role in immune activity of spinal TB. Terbium 64-66 tumor necrosis factor Oryctolagus cuniculus 0-9 34815862-4 2021 TNF-alpha and CRP has a major role in immune activity of spinal TB. Terbium 64-66 C-reactive protein Oryctolagus cuniculus 14-17 34815862-6 2021 This study aims to investigate TNFalpha and CRP value as evaluator of bone inflammation activity in Spinal TB through experimental studies in Laboratory at Veterinary Faculty, Universitas Brawijaya. Terbium 107-109 tumor necrosis factor Oryctolagus cuniculus 31-39 34815862-6 2021 This study aims to investigate TNFalpha and CRP value as evaluator of bone inflammation activity in Spinal TB through experimental studies in Laboratory at Veterinary Faculty, Universitas Brawijaya. Terbium 107-109 C-reactive protein Oryctolagus cuniculus 44-47 34804048-10 2021 A dual marker of host-derived miR-let7e-5p and M. tuberculosis-derived RNA for monitoring-TB treatment based in serum EVs. Terbium 90-92 membrane associated ring-CH-type finger 8 Homo sapiens 30-33 34804048-10 2021 A dual marker of host-derived miR-let7e-5p and M. tuberculosis-derived RNA for monitoring-TB treatment based in serum EVs. Terbium 90-92 microRNA let-7e Homo sapiens 34-39 34517050-10 2021 Despite adequate CD4 counts, women with HIV express less IFN-gamma than women without HIV , which may explain the high TB incidence in postpartum women with HIV. Terbium 119-121 interferon gamma Homo sapiens 57-66 34717654-11 2021 CONCLUSION: Our results suggest that the combination of TB/PTX@RTK micelle-mediated chemo-PDT with anti-PD-L1 monoclonal antibodies can synergistically enhance systemic anti-tumor effects, and provide a novel insight into the development of new nanomedicine with precise controlled release and multimodal therapy to enhance the therapeutic efficacy of HCC. Terbium 56-58 CD274 molecule Homo sapiens 104-109 34699542-3 2021 Feasibility of Find cases Actively, Separate safely and Treat effectively (FAST) Strategy helps to improve the early diagnosis of tuberculosis cases among inpatient settings as well as out patient department patients and prevent TB transmission in hospital. Terbium 229-231 Fas activated serine/threonine kinase Homo sapiens 75-79 34856472-9 2022 The involvement of SOCS1 has also been suggested in the regulation of the micro immune environment in TB. Terbium 102-104 suppressor of cytokine signaling 1 Homo sapiens 19-24 34685683-4 2021 Comparisons between TB and control/LTBI showed significant differential expression of all three genes (NPC2high p < 0.01, DOCK9low p < 0.01, and EPHA4low p < 0.05). Terbium 20-22 NPC intracellular cholesterol transporter 2 Homo sapiens 103-107 34685683-4 2021 Comparisons between TB and control/LTBI showed significant differential expression of all three genes (NPC2high p < 0.01, DOCK9low p < 0.01, and EPHA4low p < 0.05). Terbium 20-22 dedicator of cytokinesis 9 Homo sapiens 127-132 34685683-4 2021 Comparisons between TB and control/LTBI showed significant differential expression of all three genes (NPC2high p < 0.01, DOCK9low p < 0.01, and EPHA4low p < 0.05). Terbium 20-22 EPH receptor A4 Homo sapiens 155-160 34685683-5 2021 NPC2high had the highest mean area under the ROC curve (AUROC) for the differentiation of TB vs. controls (0.95) and LTBI (0.94). Terbium 90-92 NPC intracellular cholesterol transporter 2 Homo sapiens 0-4 34685683-6 2021 In addition, NPC2 accurately distinguished TB from the clinically similar conditions pneumonia (AUROC, 0.88), non-active sarcoidosis (0.87), and lung cancer (0.86), but not from active sarcoidosis (0.66). Terbium 43-45 NPC intracellular cholesterol transporter 2 Homo sapiens 13-17 34691079-5 2021 We confirmed previous observations demonstrating that TB-IRIS individuals display pronounced CD4+ lymphopenia prior to ART initiation. Terbium 54-56 CD4 molecule Homo sapiens 93-96 34691079-7 2021 Importantly, we demonstrate that TB-IRIS subjects display higher frequencies of cytotoxic CD8+ T lymphocytes which is not affected by ART. Terbium 33-35 CD8a molecule Homo sapiens 90-93 34612182-11 2021 FAST reduced the time from hospital admission to the start of TB treatment (HR, 2.11; 95% CI, 1.39-3.21; P < .001). Terbium 62-64 Fas activated serine/threonine kinase Homo sapiens 0-4 34591952-1 2021 A novel strategy was developed for the detection of methotrexate (MTX) via the quenching effect of MTX on the fluorescence intensity of terbium-doped dendritic silica particles (Tb@KCC-1). Terbium 178-180 solute carrier family 12 member 4 Homo sapiens 181-186 34293708-9 2021 RESULTS: We determined that high TB in breast invasive ductal carcinoma cases was associated with low survival time, metastasis, axillary lymph node metastasis, angiolymphatic invasion, advanced stage (pT3), high Ki-67 proliferation index, progesterone receptor (PR) loss, and advanced age. Terbium 33-35 progesterone receptor Homo sapiens 240-261 34293708-9 2021 RESULTS: We determined that high TB in breast invasive ductal carcinoma cases was associated with low survival time, metastasis, axillary lymph node metastasis, angiolymphatic invasion, advanced stage (pT3), high Ki-67 proliferation index, progesterone receptor (PR) loss, and advanced age. Terbium 33-35 progesterone receptor Homo sapiens 263-265 34503465-13 2021 CONCLUSIONS: The young age at presentation with severe clinical and laboratory manifestations may reflect local epidemiology as TB continues to be widespread in the country. Terbium 128-130 renin binding protein Homo sapiens 23-26 34382270-12 2021 Furthermore, due to the specific binding between AS1411 and nucleolin up-expressed in cancer cells, the AS-nFAp:Gd/Tb possessed excellent AS1411-targeted fluorescence and MRI imaging properties. Terbium 115-117 nucleolin Homo sapiens 60-69 34314164-2 2021 In this work, the rare-earth (RE) cluster-based MOF Y-CU-10 with shp topology was modified through transmetalation using a series of RE ions, including La(III), Nd(III), Eu(III), Tb(III), Er(III), Tm(III), and Yb(III). Terbium 179-181 nuclear receptor subfamily 0 group B member 2 Homo sapiens 65-68 34304255-1 2021 Combination of phosphoryl and calix(4)arene moieties in the same organic framework (LPO) directs the formation of homoleptic double-decker complexes (LnIII(LPO)2)(OTf)3 for Ln = Tb and Dy, with the latter displaying slow relaxation of the magnetisation. Terbium 178-180 lactoperoxidase Homo sapiens 84-87 34444022-11 2021 The rate was higher for TN (43%) than TN/TB (25%). Terbium 41-43 C-type lectin domain family 3 member B Homo sapiens 38-40 34615586-0 2021 Clinical experience of TB in patients treated with anti-TNF-alpha. Terbium 23-25 tumor necrosis factor Homo sapiens 56-65 34597347-10 2021 PDL1 levels moderately correlated with plasma TNFalpha, IL6, IP10, IFNgamma and IL10 level in TB subjects whereas weakly correlated with TNFalpha and IP10 in HIV patients. Terbium 94-96 CD274 molecule Homo sapiens 0-4 34679041-8 2021 Indirect ELISA assay showed that mice immunized with TB-Cap-CD154 and TB-Cap-GM-CSF fusion proteins produced higher PCV2-specific antibodies than mice immunized with the TB-Cap and a commercial vaccine (p < 0.0001). Terbium 53-55 CD40 ligand Mus musculus 60-65 34679041-11 2021 The transcription levels of IL-2, IFN-gamma, IL-4 and IL-10 cytokines in the TB-Cap, TB-Cap-CD154 and TB-Cap-GM-CSF groups were significantly higher than those in the PBS and recombinant vaccine groups (p < 0.0001). Terbium 77-79 interleukin 2 Homo sapiens 28-32 34679041-11 2021 The transcription levels of IL-2, IFN-gamma, IL-4 and IL-10 cytokines in the TB-Cap, TB-Cap-CD154 and TB-Cap-GM-CSF groups were significantly higher than those in the PBS and recombinant vaccine groups (p < 0.0001). Terbium 77-79 interferon gamma Homo sapiens 34-43 34679041-11 2021 The transcription levels of IL-2, IFN-gamma, IL-4 and IL-10 cytokines in the TB-Cap, TB-Cap-CD154 and TB-Cap-GM-CSF groups were significantly higher than those in the PBS and recombinant vaccine groups (p < 0.0001). Terbium 77-79 interleukin 4 Homo sapiens 45-49 34679041-11 2021 The transcription levels of IL-2, IFN-gamma, IL-4 and IL-10 cytokines in the TB-Cap, TB-Cap-CD154 and TB-Cap-GM-CSF groups were significantly higher than those in the PBS and recombinant vaccine groups (p < 0.0001). Terbium 77-79 interleukin 10 Homo sapiens 54-59 34679041-11 2021 The transcription levels of IL-2, IFN-gamma, IL-4 and IL-10 cytokines in the TB-Cap, TB-Cap-CD154 and TB-Cap-GM-CSF groups were significantly higher than those in the PBS and recombinant vaccine groups (p < 0.0001). Terbium 102-104 interleukin 2 Homo sapiens 28-32 34679041-11 2021 The transcription levels of IL-2, IFN-gamma, IL-4 and IL-10 cytokines in the TB-Cap, TB-Cap-CD154 and TB-Cap-GM-CSF groups were significantly higher than those in the PBS and recombinant vaccine groups (p < 0.0001). Terbium 102-104 interferon gamma Homo sapiens 34-43 34679041-11 2021 The transcription levels of IL-2, IFN-gamma, IL-4 and IL-10 cytokines in the TB-Cap, TB-Cap-CD154 and TB-Cap-GM-CSF groups were significantly higher than those in the PBS and recombinant vaccine groups (p < 0.0001). Terbium 102-104 interleukin 4 Homo sapiens 45-49 34679041-11 2021 The transcription levels of IL-2, IFN-gamma, IL-4 and IL-10 cytokines in the TB-Cap, TB-Cap-CD154 and TB-Cap-GM-CSF groups were significantly higher than those in the PBS and recombinant vaccine groups (p < 0.0001). Terbium 102-104 interleukin 10 Homo sapiens 54-59 34679041-11 2021 The transcription levels of IL-2, IFN-gamma, IL-4 and IL-10 cytokines in the TB-Cap, TB-Cap-CD154 and TB-Cap-GM-CSF groups were significantly higher than those in the PBS and recombinant vaccine groups (p < 0.0001). Terbium 102-104 colony stimulating factor 2 Homo sapiens 109-115 34679041-14 2021 The novel TB-Cap-CD154 and TB-Cap-GM-CSF subunit vaccine has the potential to be used for the prevention and control of PCVAD. Terbium 10-12 CD40 ligand Homo sapiens 17-22 34679041-14 2021 The novel TB-Cap-CD154 and TB-Cap-GM-CSF subunit vaccine has the potential to be used for the prevention and control of PCVAD. Terbium 27-29 colony stimulating factor 2 Homo sapiens 34-40 34252302-8 2021 The TTP model built depicts a novel phase 2B surrogate endpoint that can inform early assessment of experimental treatment efficacy and treatment failure or relapse in patients treated with shorter and novel TB treatment regimens, improving efficiency of phase 2 clinical trials. Terbium 208-210 ZFP36 ring finger protein Homo sapiens 4-7 34378584-0 2021 Terbium doping of graphitic carbon nitride endows a highly sensitive ratiometric fluorescence assay of alkaline phosphatase. Terbium 0-7 alkaline phosphatase, placental Homo sapiens 103-123 34378584-2 2021 The modification of g-C3N4:Tb with HOOC-PEG-COOH provides a ratiometric fluorescent probe which ensures highly sensitive detection of alkaline phosphatase (ALP) activity based on the inner filter effect (IFE). Terbium 27-29 alkaline phosphatase, placental Homo sapiens 134-154 34378584-2 2021 The modification of g-C3N4:Tb with HOOC-PEG-COOH provides a ratiometric fluorescent probe which ensures highly sensitive detection of alkaline phosphatase (ALP) activity based on the inner filter effect (IFE). Terbium 27-29 alkaline phosphatase, placental Homo sapiens 156-159 34482785-6 2022 high-sensitivity C-reactive protein, being a non-specific inflammatory marker could be an adjunct tool for TB prognosis. Terbium 107-109 C-reactive protein Homo sapiens 17-35 34472583-8 2021 Loss of IgA was significantly associated with age (p=0.023) and a previous diagnosis of TB (p=0.018). Terbium 88-90 CD79a molecule Homo sapiens 8-11 34358992-5 2021 Some of the leucocyte frequencies (atypical memory B cells, pDCs, myeloid-derived suppressor cells, CD4+ effector and CD8+ central memory was increased; activated memory and plasma B cell, mDCs, classical, non-classical, intermediate monocytes, T regs, CD4+ TEMRA, CD4+, CD8+ naive and effector memory cells and CD8+ central memory cells were decreased) were significantly modulated after anti-TB treatment among TBL individuals. Terbium 394-396 CD4 molecule Homo sapiens 100-103 34358992-5 2021 Some of the leucocyte frequencies (atypical memory B cells, pDCs, myeloid-derived suppressor cells, CD4+ effector and CD8+ central memory was increased; activated memory and plasma B cell, mDCs, classical, non-classical, intermediate monocytes, T regs, CD4+ TEMRA, CD4+, CD8+ naive and effector memory cells and CD8+ central memory cells were decreased) were significantly modulated after anti-TB treatment among TBL individuals. Terbium 394-396 CD8a molecule Homo sapiens 118-121 34358992-5 2021 Some of the leucocyte frequencies (atypical memory B cells, pDCs, myeloid-derived suppressor cells, CD4+ effector and CD8+ central memory was increased; activated memory and plasma B cell, mDCs, classical, non-classical, intermediate monocytes, T regs, CD4+ TEMRA, CD4+, CD8+ naive and effector memory cells and CD8+ central memory cells were decreased) were significantly modulated after anti-TB treatment among TBL individuals. Terbium 394-396 CD4 molecule Homo sapiens 253-256 34358992-5 2021 Some of the leucocyte frequencies (atypical memory B cells, pDCs, myeloid-derived suppressor cells, CD4+ effector and CD8+ central memory was increased; activated memory and plasma B cell, mDCs, classical, non-classical, intermediate monocytes, T regs, CD4+ TEMRA, CD4+, CD8+ naive and effector memory cells and CD8+ central memory cells were decreased) were significantly modulated after anti-TB treatment among TBL individuals. Terbium 394-396 CD4 molecule Homo sapiens 265-268 34358992-5 2021 Some of the leucocyte frequencies (atypical memory B cells, pDCs, myeloid-derived suppressor cells, CD4+ effector and CD8+ central memory was increased; activated memory and plasma B cell, mDCs, classical, non-classical, intermediate monocytes, T regs, CD4+ TEMRA, CD4+, CD8+ naive and effector memory cells and CD8+ central memory cells were decreased) were significantly modulated after anti-TB treatment among TBL individuals. Terbium 394-396 CD8a molecule Homo sapiens 271-274 34358992-5 2021 Some of the leucocyte frequencies (atypical memory B cells, pDCs, myeloid-derived suppressor cells, CD4+ effector and CD8+ central memory was increased; activated memory and plasma B cell, mDCs, classical, non-classical, intermediate monocytes, T regs, CD4+ TEMRA, CD4+, CD8+ naive and effector memory cells and CD8+ central memory cells were decreased) were significantly modulated after anti-TB treatment among TBL individuals. Terbium 394-396 CD8a molecule Homo sapiens 312-315 34441452-1 2021 OBJECTIVE: To compare the radiomic features of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and intratumoral heterogeneity according to tumor budding (TB) status and to develop a prediction model for the TB status using the radiomic feature of 18F-FDG PET/CT in patients with cervical cancer. Terbium 249-251 mastermind like domain containing 1 Homo sapiens 47-51 34591952-2 2021 The fluorescence intensity of Tb@KCC-1 can be effectively quenched by MTX at 546 nm under an excitation wavelength of 233 nm. Terbium 30-32 solute carrier family 12 member 4 Homo sapiens 33-38 34409172-11 2021 Four hundred fifty seven (27.7%) cases were diagnosed with extra pulmonary TB (EPTB) and 1194 (72.3%) were pulmonary TB patients out of which, 376 (73.6%) were smear-positive pulmonary TB (PTB+). Terbium 185-187 polypyrimidine tract binding protein 1 Homo sapiens 189-192 34360313-8 2021 TB antigen-stimulated IFN-gamma, I-TAC, and MIG levels were all significantly higher in the TB-LAP patients than in the controls and non-TB-LAP patients. Terbium 0-2 interferon gamma Homo sapiens 22-31 34360313-8 2021 TB antigen-stimulated IFN-gamma, I-TAC, and MIG levels were all significantly higher in the TB-LAP patients than in the controls and non-TB-LAP patients. Terbium 0-2 C-X-C motif chemokine ligand 11 Homo sapiens 33-38 34360313-8 2021 TB antigen-stimulated IFN-gamma, I-TAC, and MIG levels were all significantly higher in the TB-LAP patients than in the controls and non-TB-LAP patients. Terbium 0-2 C-X-C motif chemokine ligand 9 Homo sapiens 44-47 34360313-8 2021 TB antigen-stimulated IFN-gamma, I-TAC, and MIG levels were all significantly higher in the TB-LAP patients than in the controls and non-TB-LAP patients. Terbium 0-2 LAP Homo sapiens 95-98 34360313-8 2021 TB antigen-stimulated IFN-gamma, I-TAC, and MIG levels were all significantly higher in the TB-LAP patients than in the controls and non-TB-LAP patients. Terbium 0-2 LAP Homo sapiens 140-143 34360313-8 2021 TB antigen-stimulated IFN-gamma, I-TAC, and MIG levels were all significantly higher in the TB-LAP patients than in the controls and non-TB-LAP patients. Terbium 92-94 interferon gamma Homo sapiens 22-31 34360313-8 2021 TB antigen-stimulated IFN-gamma, I-TAC, and MIG levels were all significantly higher in the TB-LAP patients than in the controls and non-TB-LAP patients. Terbium 92-94 C-X-C motif chemokine ligand 11 Homo sapiens 33-38 34360313-8 2021 TB antigen-stimulated IFN-gamma, I-TAC, and MIG levels were all significantly higher in the TB-LAP patients than in the controls and non-TB-LAP patients. Terbium 92-94 C-X-C motif chemokine ligand 9 Homo sapiens 44-47 34325678-1 2021 BACKGROUND: One-handed backhand (OB) and two-handed backhand (TB) styles are commonly used in tennis, but only TB generates loadings on the non-dominant arm and a greater extension torque on the rear leg, leading to a greater axial torque involving rotation of the hip and trunk. Terbium 111-113 hedgehog interacting protein Homo sapiens 265-268 34256363-2 2021 In this study, we developed a novel acetylcholinesterase (AChE) biosensor based on Au-Tb alloy nanospheres (NSs) for rapid and sensitive detection of OPs for the first time. Terbium 86-88 acetylcholinesterase (Cartwright blood group) Homo sapiens 36-56 34256363-2 2021 In this study, we developed a novel acetylcholinesterase (AChE) biosensor based on Au-Tb alloy nanospheres (NSs) for rapid and sensitive detection of OPs for the first time. Terbium 86-88 acetylcholinesterase (Cartwright blood group) Homo sapiens 58-62 34360313-8 2021 TB antigen-stimulated IFN-gamma, I-TAC, and MIG levels were all significantly higher in the TB-LAP patients than in the controls and non-TB-LAP patients. Terbium 92-94 LAP Homo sapiens 95-98 34360313-9 2021 The levels of I-TAC and MIG, but not IFN-gamma, showed significant differences between the TB-LAP patients and IGRA-positive controls. Terbium 91-93 C-X-C motif chemokine ligand 11 Homo sapiens 14-19 34304400-1 2021 We previously reported that M. tb on its own as well as together with HIV inhibits macrophage apoptosis by upregulating the expression of Bcl2 and Inhibitor of Apoptosis (IAP). Terbium 31-33 BCL2 apoptosis regulator Homo sapiens 138-142 34360313-9 2021 The levels of I-TAC and MIG, but not IFN-gamma, showed significant differences between the TB-LAP patients and IGRA-positive controls. Terbium 91-93 C-X-C motif chemokine ligand 9 Homo sapiens 24-27 34360313-9 2021 The levels of I-TAC and MIG, but not IFN-gamma, showed significant differences between the TB-LAP patients and IGRA-positive controls. Terbium 91-93 LAP Homo sapiens 94-97 34360313-10 2021 Area under the receiver operating characteristic curves (AUROCs) of IFN-gamma, I-TAC, and MIG were 0.955, 0.958, and 0.959, respectively, for differentiating TB-LAP from control group, and were 0.912, 0.956, and 0.936, respectively, for differentiating TB-LAP from non-TB-LAP. Terbium 158-160 interferon gamma Homo sapiens 68-77 34360313-10 2021 Area under the receiver operating characteristic curves (AUROCs) of IFN-gamma, I-TAC, and MIG were 0.955, 0.958, and 0.959, respectively, for differentiating TB-LAP from control group, and were 0.912, 0.956, and 0.936, respectively, for differentiating TB-LAP from non-TB-LAP. Terbium 158-160 C-X-C motif chemokine ligand 11 Homo sapiens 79-84 34360313-10 2021 Area under the receiver operating characteristic curves (AUROCs) of IFN-gamma, I-TAC, and MIG were 0.955, 0.958, and 0.959, respectively, for differentiating TB-LAP from control group, and were 0.912, 0.956, and 0.936, respectively, for differentiating TB-LAP from non-TB-LAP. Terbium 158-160 C-X-C motif chemokine ligand 9 Homo sapiens 90-93 34360313-10 2021 Area under the receiver operating characteristic curves (AUROCs) of IFN-gamma, I-TAC, and MIG were 0.955, 0.958, and 0.959, respectively, for differentiating TB-LAP from control group, and were 0.912, 0.956, and 0.936, respectively, for differentiating TB-LAP from non-TB-LAP. Terbium 253-255 C-X-C motif chemokine ligand 9 Homo sapiens 90-93 34360313-11 2021 In conclusion, the TB antigen-stimulated MIG and I-TAC could be useful biomarkers in the diagnosis of TB-LAP. Terbium 19-21 C-X-C motif chemokine ligand 9 Homo sapiens 41-44 34360313-11 2021 In conclusion, the TB antigen-stimulated MIG and I-TAC could be useful biomarkers in the diagnosis of TB-LAP. Terbium 19-21 C-X-C motif chemokine ligand 11 Homo sapiens 49-54 34360313-11 2021 In conclusion, the TB antigen-stimulated MIG and I-TAC could be useful biomarkers in the diagnosis of TB-LAP. Terbium 19-21 LAP Homo sapiens 105-108 34360313-11 2021 In conclusion, the TB antigen-stimulated MIG and I-TAC could be useful biomarkers in the diagnosis of TB-LAP. Terbium 102-104 C-X-C motif chemokine ligand 9 Homo sapiens 41-44 34360313-11 2021 In conclusion, the TB antigen-stimulated MIG and I-TAC could be useful biomarkers in the diagnosis of TB-LAP. Terbium 102-104 C-X-C motif chemokine ligand 11 Homo sapiens 49-54 34360313-11 2021 In conclusion, the TB antigen-stimulated MIG and I-TAC could be useful biomarkers in the diagnosis of TB-LAP. Terbium 102-104 LAP Homo sapiens 105-108 34386510-6 2021 We applied a backward stepwise multivariable logistic regression model to identify characteristics in each age group associated with unfavorable TB treatment outcomes. Terbium 145-147 renin binding protein Homo sapiens 107-110 34361272-0 2021 Magnetic Field-Assisted Photocatalytic Degradation of Organic Pollutants over Bi1-xRxFeO3 (R = Ce, Tb; x = 0.00, 0.05, 0.10 and 0.15) Nanostructures. Terbium 99-101 transmembrane BAX inhibitor motif containing 6 Homo sapiens 78-81 34111934-14 2021 Conversely, ATG7 knockdown in NRVMs abolished these beneficial effects of TB on cell death and ROS reduction. Terbium 74-76 autophagy related 7 Mus musculus 12-16 34170146-4 2021 Interestingly, this Tb-MOF exhibited dual luminescence owing to the partial energy transfer from the antenna H4L to Tb3+. Terbium 20-22 H4 clustered histone 7 Homo sapiens 109-112 34099205-16 2021 CONCLUSION: TBM is associated with high morbidity and mortality in children especially in India where Burden of TB is high. Terbium 112-114 mucin 5AC, oligomeric mucus/gel-forming Homo sapiens 12-15 34278932-11 2021 Furthermore, mice in group TB showed significant loss of body weight and muscle weight in which XO activity, 8-OHdG, and expression of IL-6 were significantly increased compared to those in group C. Febuxostat administration not only significantly improved the body weight and muscleweight, but also reduced markers of oxidative stress and pro-inflammatory cytokines. Terbium 27-29 interleukin 6 Mus musculus 135-139 34176483-8 2021 RESULTS: We observed that the percentages of "CD27-IFN-gamma+CD4+" cells were significantly increased in the SN-TB group compared with the HC and TB-C groups (AUC was 0.88, sensitivity was 82.14%, specificity was 80.00%, and P < 0.0001). Terbium 146-148 CD27 molecule Homo sapiens 46-50 34203413-5 2021 When RNA sequencing (RNA-seq) was used to investigate the mechanism underlying TB-CM-induced cell migration on scratch-wounded HNDFs, the increased expression of genes associated with C-X-C motif ligand (CXCL) chemokines, toll-like receptors, and nuclear factor-kappa B (NF-kappaB) signaling was observed. Terbium 79-81 nuclear factor kappa B subunit 1 Homo sapiens 247-269 34203413-5 2021 When RNA sequencing (RNA-seq) was used to investigate the mechanism underlying TB-CM-induced cell migration on scratch-wounded HNDFs, the increased expression of genes associated with C-X-C motif ligand (CXCL) chemokines, toll-like receptors, and nuclear factor-kappa B (NF-kappaB) signaling was observed. Terbium 79-81 nuclear factor kappa B subunit 1 Homo sapiens 271-280 34176483-8 2021 RESULTS: We observed that the percentages of "CD27-IFN-gamma+CD4+" cells were significantly increased in the SN-TB group compared with the HC and TB-C groups (AUC was 0.88, sensitivity was 82.14%, specificity was 80.00%, and P < 0.0001). Terbium 146-148 interferon gamma Homo sapiens 51-60 34176483-8 2021 RESULTS: We observed that the percentages of "CD27-IFN-gamma+CD4+" cells were significantly increased in the SN-TB group compared with the HC and TB-C groups (AUC was 0.88, sensitivity was 82.14%, specificity was 80.00%, and P < 0.0001). Terbium 146-148 CD4 molecule Homo sapiens 61-64 34076597-7 2021 A bioinformatic analysis revealed that the core domain in the middle (Leu117-Asp462 in Sc-Rsm22) resembles the corresponding region in Tb-Rsm22, including a Rossmann-like methyltransferase fold followed by a zinc-finger-like structure. Terbium 135-137 mitochondrial 37S ribosomal protein RSM22 Saccharomyces cerevisiae S288C 138-143 34085301-9 2022 Additionally, with the information of PPT, a significant difference was observed between mean SWSs for the sides with and without TBs and/or MTrPs, for PPT values between 0 and 50 N/cm2 (P < .005), but for PPT values between 50 and 90 N/cm2 , it was difficult to differentiate mean SWSs with and without TBs and/or MTrPs. Terbium 130-133 palmitoyl-protein thioesterase 1 Homo sapiens 38-41 34081721-3 2021 This study aimed to compare the EMG-force relationships of the medial (TB-Med), lateral (TB-Lat), and long heads (TB-Long) of the TB. Terbium 89-91 linker for activation of T cells Homo sapiens 92-95 34076597-9 2021 The first half of the C-terminal domain is likely to form an OB-fold, which is typically found in RNA-binding proteins and is also seen in the Tb-Rsm22 structure. Terbium 143-145 mitochondrial 37S ribosomal protein RSM22 Saccharomyces cerevisiae S288C 146-151 34240047-4 2021 Objectives: To evaluate the diagnostic value of Xpert MTB/RIF assay on diagnosis of TB in pleural tissue obtained via blind closed pleural biopsy. Terbium 84-86 ras homolog family member F, filopodia associated Homo sapiens 58-61 35398293-8 2022 W-PTH increased Tb.vBMD (+5.3%, +1.9%), maintained Ct.vTMD (-0.7%, +0.2%) compared with D-PTH, increased Ct.Th (+0.6%, +3.6%), and increased FL (+4.9%, +4.5%). Terbium 16-18 parathyroid hormone Homo sapiens 2-5 34336605-6 2021 Methods: In this assay, a biotinylated peptide was used as a G9a substrate in conjugation with streptavidin-coated ZnS/CdSe QD as FRET acceptor, and an anti-mark antibody labeled with Tb as a donor. Terbium 184-186 euchromatic histone lysine methyltransferase 2 Homo sapiens 61-64 34336605-12 2021 Conclusion: It was shown that Tb-to-QD FRET is an outstanding platform for developing a homogenous assay for the G9a enzyme and its inhibitors. Terbium 30-32 euchromatic histone lysine methyltransferase 2 Homo sapiens 113-116 35583194-4 2022 Therefore, we reported an easily available ratiometric fluorescent probe, TB-BChE, with aggregation-induced emission (AIE) characteristics for ratiometric imaging of BChE. Terbium 74-76 butyrylcholinesterase Homo sapiens 166-170 35583194-5 2022 TB-BChE demonstrated excellent sensitivity (LOD = 39.24 ng mL-1) and specificity for BChE. Terbium 0-2 butyrylcholinesterase Homo sapiens 3-7 35583194-5 2022 TB-BChE demonstrated excellent sensitivity (LOD = 39.24 ng mL-1) and specificity for BChE. Terbium 0-2 L1 cell adhesion molecule Mus musculus 59-63 35583194-5 2022 TB-BChE demonstrated excellent sensitivity (LOD = 39.24 ng mL-1) and specificity for BChE. Terbium 0-2 butyrylcholinesterase Homo sapiens 85-89 35583194-6 2022 Moreover, we have successfully studied the ratiometric imaging of TB-BChE to BChE in a nonalcoholic fatty liver disease model. Terbium 66-68 butyrylcholinesterase Homo sapiens 69-73 35583194-6 2022 Moreover, we have successfully studied the ratiometric imaging of TB-BChE to BChE in a nonalcoholic fatty liver disease model. Terbium 66-68 butyrylcholinesterase Homo sapiens 77-81 35613045-4 2022 We developed a novel scoring system that incorporates TB and PDC into a single parameter ("Combined Score"; CS), eliminating the need for such cutoffs and allowing the prognostic value of PDC to be captured alongside TB. Terbium 54-56 citrate synthase Homo sapiens 108-110 35602429-5 2022 Similarly, RTE extruded snacks fortified by 10% TB exhibited higher DPPH, FRAP, ABTS, hydroxyl radical activities, reducing power, and essential amino acids, such as lysine, leucine, isoleucine, cysteine, threonine, tyrosine, and methionine derived by HPLC. Terbium 48-50 mechanistic target of rapamycin kinase Homo sapiens 74-78 35594958-6 2022 Pearson"s correlation coefficient and hierarchical cluster analysis revealed that PN in TB-EPS was the major factor influencing the effect of sludge electro-dewatering. Terbium 88-90 U6 snRNA biogenesis phosphodiesterase 1 Homo sapiens 82-84 35608549-7 2022 Among the 29 symptom-negative/CXR-abnormal child contacts, 20% (3/15) of the isoniazid recipients developed incident TB, compared to 57% (8/14) of those who did not receive isoniazid preventive therapy (82% IPT efficacy). Terbium 117-119 tRNA isopentenyltransferase 1 Homo sapiens 207-210 35590345-7 2022 RESULTS: A total of 953 sputum-smear positive patients were enrolled, of which 917 were confirmed as positive for TB by either Xpert MTB/RIF or culture. Terbium 114-116 ras homolog family member F, filopodia associated Homo sapiens 137-140 35491036-3 2022 By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite. Terbium 141-143 alkaline phosphatase, placental Homo sapiens 103-123 35491036-5 2022 However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite. Terbium 172-174 alkaline phosphatase, placental Homo sapiens 43-46 35505474-13 2022 The increase in low-level INH resistance mutation inhA-c-15t may be associated with ethionamide/prothionamide resistance, and this should be taken into account when designing DR-TB regimen. Terbium 178-180 inhibin subunit alpha Homo sapiens 50-54 35505481-1 2022 INTRODUCTION: Xpert Ultra (Ultra) was developed to improve the detection of TB; however, data on Ultra s diagnostic accuracy in extrapulmonary TB (EPTB) are limited.METHODS: In this prospective diagnostic accuracy study, 242 EPTB samples were subjected to Ultra and Xpert MTB/Rif (Xpert) testing, and these were compared with both culture and a composite gold standard.RESULTS: Compared to culture, Ultra sensitivity and specificity using bone, cerebrospinal fluid (CSF), lymph node and tissue samples, and overall were respectively 100% and 77.3%, 75% and 100%, 87.5% and 87.5%, 100% and 87%, and 89.7% and 87.4%; in comparison to the composite gold standard, Ultra s sensitivity and specificity were respectively 66.7% and 100%, 17.6% and 100%, 46.9% and 95.7%, 38.5% and 94.1%, and 46.2% and 96.9%. Terbium 76-78 ras homolog family member F, filopodia associated Homo sapiens 276-279 35486232-3 2022 Given the huge variability in the prevalence of TB across age-groups in China, the vaccination, diagnostic techniques, and treatment for different age-groups may have different effects. Terbium 48-50 renin binding protein Homo sapiens 58-61 35486232-3 2022 Given the huge variability in the prevalence of TB across age-groups in China, the vaccination, diagnostic techniques, and treatment for different age-groups may have different effects. Terbium 48-50 renin binding protein Homo sapiens 147-150 34189157-5 2021 Active TB at follow-up was defined by positive sputum Xpert-TB/RIF or culture. Terbium 7-9 ras homolog family member F, filopodia associated Homo sapiens 54-66 35620155-9 2022 However, we unexpectedly found autistic participants with larger auditory Tb ERP amplitudes had reduced hearing acuity, even though all participants had hearing acuity in the non-clinical range. Terbium 74-76 ETS transcription factor ELK3 Homo sapiens 77-80 35550158-8 2022 RESULTS: Lower Tb was associated with increased NFT burden, as well as increased plasma and CSF P-tau levels (p < 0.05). Terbium 15-17 microtubule associated protein tau Homo sapiens 98-101 35550158-11 2022 CONCLUSIONS: These results, the first available for human, suggest that lower Tb in older adults may be associated with increased soluble and aggregated tau pathology. Terbium 78-80 microtubule associated protein tau Homo sapiens 153-156 35325275-2 2022 Studies indicated that TAP plays a key role in the presentation and transport of antigenic peptides during anti-M.tb infection. Terbium 114-116 nuclear RNA export factor 1 Homo sapiens 23-26 35544632-2 2022 METHODOLOGY: Through a cross-sectional descriptive study, this study aims to determine the predictors of knowledge about TB among 261 mothers of children under 5 years of age attending Child Welfare Clinic, Bingham University Teaching Hospital, Jos, Plateau State, Nigeria. Terbium 121-123 ataxin 3 Homo sapiens 245-248 35491036-3 2022 By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite. Terbium 141-143 alkaline phosphatase, placental Homo sapiens 125-128 35491036-3 2022 By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite. Terbium 231-233 alkaline phosphatase, placental Homo sapiens 103-123 35491036-3 2022 By employing terbium ion (Tb3+) as a metal node and guanine monophosphate (GMP) as a bridge ligand, an alkaline phosphatase (ALP)-responsive Tb/GMP CPs was fabricated, which allows amyloglucosidase (GA) to be integrated to form GA@Tb/GMP composite. Terbium 231-233 alkaline phosphatase, placental Homo sapiens 125-128 35491036-5 2022 However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite. Terbium 9-11 alkaline phosphatase, placental Homo sapiens 43-46 35491036-5 2022 However, Tb/GMP CPs is highly sensitive to ALP, which can hydrolyze the phosphate group of GMP to destroy the structure of Tb/GMP CPs, leading to the release of GA from GA@Tb/GMP composite. Terbium 123-125 alkaline phosphatase, placental Homo sapiens 43-46 35452629-2 2022 We sought to find the correlation between the serum levels of SAA1 and IL-1beta in response to ATT in adult patients with pulmonary TB (PTB) or extra-pulmonary TB (EPTB). Terbium 160-162 serum amyloid A1 Homo sapiens 62-66 35443636-6 2022 Group TB exhibited significantly smaller left pedicle-aorta distance, pedicular line-aorta distance and vertebra/rib-aorta distance than those in group NC at the T5-T10 levels, but bigger at the L1-3 levels. Terbium 6-8 immunoglobulin kappa variable 2-4 (pseudogene) Homo sapiens 195-199 35477378-7 2022 The poisoning symptoms of TB were relieved in all patients, and ESR (42.09 +- 9.53 vs 8.04 +- 5.41, P < 0.05) and CRP (30.37 +- 16.02 vs 7.4 +- 2.68, P < 0.05) were decreased at the 3 postoperative months in the comparison of the preoperative. Terbium 26-28 C-reactive protein Homo sapiens 114-117 35470464-10 2022 WHAT IS NEW AND CONCLUSION: Based on this 1:4 individual matched case-control study, SNP rs11660001 in the FECH gene may be associated with susceptibility to AT-DILI in Chinese female anti-TB treatment patients. Terbium 189-191 ferrochelatase Homo sapiens 107-111 35625355-4 2022 Endogenous VIP, acting on VPAC1 (but not VPAC2) receptors, inhibited CA1 hippocampal LTP induced by TBS in young adult Wistar rats and this effect was dependent on GABAergic transmission and relied on the integrity of NMDA and CaMKII-dependent LTP expression mechanisms but not on PKA and PKC activity. Terbium 100-103 vasoactive intestinal peptide Rattus norvegicus 11-14 35380559-6 2022 As it may be expected, Sr2Tb3B27-deltaO46 and Ba2Eu3B27-deltaO46 (delta = 2/3) are promising green (Tb) and red (Eu) components for use in WLEDs. Terbium 100-102 delta like canonical Notch ligand 3 Homo sapiens 46-77 35452629-2 2022 We sought to find the correlation between the serum levels of SAA1 and IL-1beta in response to ATT in adult patients with pulmonary TB (PTB) or extra-pulmonary TB (EPTB). Terbium 160-162 interleukin 1 alpha Homo sapiens 71-79 35388750-12 2022 Second, COPD patients in the Prior TB Group had more severe clinical symptoms: Compared with no history of tuberculosis, mMRC (p-value = 0.001) and CAT (p-value = 0.002) scores were higher in the History of tuberculosis group among COPD patients. Terbium 35-37 catalase Homo sapiens 148-151 35381636-7 2022 Results: IL-6R expression in TB group was lower than that in control group, but DNMT1 and DNMT3B expressions were higher than those in control group in CD4+T cells isolated from PBMC. Terbium 29-31 interleukin 6 receptor Homo sapiens 9-14 35432354-2 2022 Of note, TB-IRIS is characterized by exacerbated inflammation and tissue damage that occurs in response to the elevated production of CD4+ T cell-derived IFN-gamma. Terbium 9-11 CD4 molecule Homo sapiens 134-137 35432354-2 2022 Of note, TB-IRIS is characterized by exacerbated inflammation and tissue damage that occurs in response to the elevated production of CD4+ T cell-derived IFN-gamma. Terbium 9-11 interferon gamma Homo sapiens 154-163 35432354-5 2022 Results: We found that TB-IRIS individuals display higher frequencies of Antigen-experienced CD8+ T cells during the onset of IRIS and that the levels of these cells positively correlate with baseline mycobacterial smear grade. Terbium 23-25 CD8a molecule Homo sapiens 93-96 35432354-6 2022 TB-IRIS individuals exhibited higher frequencies of effector memory and lower percentages of naive CD8+ T cells than their Non-IRIS counterparts. Terbium 0-2 CD8a molecule Homo sapiens 99-102 35432354-7 2022 In both TB-IRIS and Non-IRIS patients, ART commencement was associated with fewer significant correlations among memory CD8+ T cells and cells from other immune compartments. Terbium 8-10 CD8a molecule Homo sapiens 120-123 35432354-10 2022 Furthermore, we found that CXCR3+ naive CD8+ T cells were inversely associated with the risk of TB-IRIS development. Terbium 96-98 C-X-C motif chemokine receptor 3 Homo sapiens 27-32 35432354-10 2022 Furthermore, we found that CXCR3+ naive CD8+ T cells were inversely associated with the risk of TB-IRIS development. Terbium 96-98 CD8a molecule Homo sapiens 40-43 35432354-11 2022 On the other hand, we noticed that the frequencies of CXCR3+ effector CD8+ T cells were positively associated with the probability of TB-IRIS development. Terbium 134-136 C-X-C motif chemokine receptor 3 Homo sapiens 54-59 35432354-11 2022 On the other hand, we noticed that the frequencies of CXCR3+ effector CD8+ T cells were positively associated with the probability of TB-IRIS development. Terbium 134-136 CD8a molecule Homo sapiens 70-73 35432354-12 2022 Conclusion: Our data suggest that TB-IRIS individuals display a distinct profile of memory CD8+ T cell subsets reconstitution after ART initiation. Terbium 34-36 CD8a molecule Homo sapiens 91-94 35432354-13 2022 Moreover, our data point to a differential association between the frequencies of CXCR3+ CD8+ T cells and the risk of TB-IRIS development. Terbium 118-120 C-X-C motif chemokine receptor 3 Homo sapiens 82-87 35432354-13 2022 Moreover, our data point to a differential association between the frequencies of CXCR3+ CD8+ T cells and the risk of TB-IRIS development. Terbium 118-120 CD8a molecule Homo sapiens 89-92 35432354-14 2022 Collectively, our findings lend insights into the potential role of memory CD8+ T cells in TB-IRIS pathophysiology. Terbium 91-93 CD8a molecule Homo sapiens 75-78 35345666-9 2022 CCL5 performed well in distinguishing the healthy group from the TB group (AUC = 0.723). Terbium 65-67 C-C motif chemokine ligand 5 Homo sapiens 0-4 35103916-9 2022 Postoperatively, the SG-PTB and SG-TB groups had higher postoperative GLP-1 levels than postoperative SG and SHAM groups. Terbium 35-37 glucagon Rattus norvegicus 70-75 35266939-4 2022 Non-agglomerated nanosized Ce1-xLnxO2-x/2 (Ln = Pr, Tb, particle size < 10 nm) was prepared mechanochemically from CeCl3 and Na2CO3 followed by short calcination. Terbium 52-54 carboxylesterase 1 Homo sapiens 27-30 35244135-4 2022 More importantly, porous CaF2:Ce,Tb nanoarchitectures can prevent aggregation quenching and anion exchange of PQDs. Terbium 33-35 CCR4-NOT transcription complex subunit 8 Homo sapiens 25-29 35345666-10 2022 And CCL19 performed well in distinguishing the TB group from the ORD groups (AUC = 0.811). Terbium 47-49 C-C motif chemokine ligand 19 Homo sapiens 4-9 35119086-11 2022 In the low TB-BMD subgroup the mean OC and the OPG/sRANKL ratio were lower than in the normal TB-BMD subgroup. Terbium 11-13 basic transcription factor 3 pseudogene 11 Homo sapiens 47-50 34857466-6 2022 With the addition of citrate, the fluorescence of GMP/Tb at 545 nm was significantly quenched, contrasting to the enhancement of fluorescence of CDs at 454 nm. Terbium 54-56 5'-nucleotidase, cytosolic II Homo sapiens 50-53 35195865-6 2022 In comparison with raw sludge, adsorption water proportion in TB-EPS and S-EPS was reduced after lysozyme (LZM) or freezing-thaw conditioning, which was ascribed to reduction of EPS viscosity and the weakness of water adsorption capacity. Terbium 62-64 lysozyme Homo sapiens 97-105 35195865-6 2022 In comparison with raw sludge, adsorption water proportion in TB-EPS and S-EPS was reduced after lysozyme (LZM) or freezing-thaw conditioning, which was ascribed to reduction of EPS viscosity and the weakness of water adsorption capacity. Terbium 62-64 lysozyme Homo sapiens 107-110 35163636-6 2022 An increased immunoexpression of the tissue biomarkers CASP-1, IL-33, ACE2, B1R and B2R was observed in the alveolar septum of the COVID-19 patients, associated with a higher density of IgE+ MCs, tryptase+ MCs and TB-stained MCs, in addition to the presence of intra-alveolar edema. Terbium 214-216 bradykinin receptor B1 Homo sapiens 76-87 35161072-1 2022 In this study, we investigated the effect of terbium ions (Tb3+) on the subphases of the limiting area of the molecule for the complex compound (CC) TbL3 bipy (where HL is 3-methyl-1-phenyl-4-stearoylpyrazol-5-one and bipy is 2,2"-bipyridine). Terbium 45-52 transducin beta like 3 Homo sapiens 149-153 35073927-8 2022 Histologically, intra-cerebroventricular infection of Nos2-/- mice with M.tb resembled human CNS-TB brain biopsy specimens. Terbium 97-99 nitric oxide synthase 2, inducible Mus musculus 54-58 35073927-10 2022 CONCLUSIONS: Intra-cerebroventricular infection of Nos2-/- mice with H37Rv creates a murine CNS-TB model that resembled human CNS-TB immunopathology, exhibiting the worst neurobehavioral score with a high and early mortality reflecting disease severity and its associated neurological morbidity. Terbium 96-98 nitric oxide synthase 2, inducible Mus musculus 51-55 35073927-10 2022 CONCLUSIONS: Intra-cerebroventricular infection of Nos2-/- mice with H37Rv creates a murine CNS-TB model that resembled human CNS-TB immunopathology, exhibiting the worst neurobehavioral score with a high and early mortality reflecting disease severity and its associated neurological morbidity. Terbium 130-132 nitric oxide synthase 2, inducible Mus musculus 51-55 35509359-7 2022 Results: The optimal expression level of main and control plac1 was obtained in BL21 (DE3) and TB culture medium in the presence of 0.25 mM IPTG after 24 hr of induction at 15 C. The buffer containing 2% sarkosyl produced higher yield and purity. Terbium 95-97 placental specific protein 1 Mus musculus 58-63 34969431-0 2022 VIDAS TB-IGRA reagents induce a CD4+ and CD8+ T-cell IFN-gamma response for both TB infection and active TB. Terbium 82-84 CD4 molecule Homo sapiens 33-36 34969431-0 2022 VIDAS TB-IGRA reagents induce a CD4+ and CD8+ T-cell IFN-gamma response for both TB infection and active TB. Terbium 82-84 CD8a molecule Homo sapiens 42-45 34969431-0 2022 VIDAS TB-IGRA reagents induce a CD4+ and CD8+ T-cell IFN-gamma response for both TB infection and active TB. Terbium 82-84 interferon gamma Homo sapiens 54-63 35268621-2 2022 Drugs targeting distinct cellular mechanisms including synthesis of the cell wall, lipids, proteins, and nucleic acids in Mtb are currently being used for the treatment of TB. Terbium 172-174 metallothionein 1J, pseudogene Homo sapiens 122-125 35183749-1 2022 OBJECTIVES: Interferon-gamma release assays (IGRAs), including T-SPOT.TB (TSPOT) and QuantiFERON Gold In-Tube (QFT), are important diagnostic tools for tuberculosis infection, yet little work has been done to study the performance of these tests in populations prioritized for tuberculosis testing in the United States, especially other than healthcare personnel. Terbium 70-72 interferon gamma Homo sapiens 12-28 35198736-8 2022 Results: Out of 78 participants, pro-inflammatory cytokines IFN-gamma and TNF-alpha were significantly increased in TB positive patients than TB negative patients (p < 0.05). Terbium 116-118 interferon gamma Homo sapiens 60-69 35198736-8 2022 Results: Out of 78 participants, pro-inflammatory cytokines IFN-gamma and TNF-alpha were significantly increased in TB positive patients than TB negative patients (p < 0.05). Terbium 116-118 tumor necrosis factor Homo sapiens 74-83 35198736-8 2022 Results: Out of 78 participants, pro-inflammatory cytokines IFN-gamma and TNF-alpha were significantly increased in TB positive patients than TB negative patients (p < 0.05). Terbium 142-144 tumor necrosis factor Homo sapiens 74-83 35198736-9 2022 IFN-gamma value of TB positive patients (41.26 +- 41.05) was higher than TB negative (22.94 +- 44.51) patients. Terbium 19-21 interferon gamma Homo sapiens 0-9 35198736-10 2022 TNF-alpha value (44.31 +- 64.22) of TB positive patients was higher than TB negative (15.86 +- 41.45) patients. Terbium 36-38 tumor necrosis factor Homo sapiens 0-9 35198736-13 2022 Conclusion: IFN-gamma and TNF-alpha were significantly higher in TB positive patients and it may act as a potential biomarker for diagnosis of genital tuberculosis. Terbium 65-67 interferon gamma Homo sapiens 12-21 35198736-13 2022 Conclusion: IFN-gamma and TNF-alpha were significantly higher in TB positive patients and it may act as a potential biomarker for diagnosis of genital tuberculosis. Terbium 65-67 tumor necrosis factor Homo sapiens 26-35 35145511-9 2021 CD20+, CD4+, CD68+, Foxp3+CD4+ cells were demonstrated to infiltrate higher in TM while CD20+ and CD68+ cells were also enriched in NS and TB regions respectively. Terbium 139-141 keratin 20 Homo sapiens 88-92 35119086-12 2022 The TB-Z-score values (both normal and low) correlated significantly and positively with all nutritional indices and the OPG/sRANKL ratio. Terbium 4-6 basic transcription factor 3 pseudogene 11 Homo sapiens 121-124 35119086-13 2022 The low TB-Z-score values correlated significantly and positively also with chemerin. Terbium 8-10 retinoic acid receptor responder 2 Homo sapiens 76-84 35119086-14 2022 In the low TB-BMD subgroup chemerin correlated significantly and positively with weight and BMI (expressed as absolute values), Cole index, the duration of the disease, and OPG/sRANKL ratio while its correlation with age was negative. Terbium 11-13 retinoic acid receptor responder 2 Homo sapiens 27-35 2729996-0 1989 Interaction of terbium and calcium with chicken cystatin. Terbium 15-22 cystatin C Gallus gallus 48-56 2604719-8 1989 Tb3+ (terbium ion) binding studies on the S100b.Zn2+6 complex proved that Tb3+ antagonizes only Ca2+ binding site II beta and confirmed the sequential occupation of Ca2+-binding sites on the S100b.Zn2+6 complex. Terbium 6-13 S100 calcium binding protein B Bos taurus 42-47 2499626-10 1989 In addition, the sera of untreated TB mice contained levels of IL-6 which paralleled the extent of tumor burden (serum IL-6 in day 30 MCA 106 TB mice = 420 HGF U/ml). Terbium 35-37 interleukin 6 Mus musculus 63-67 2499626-10 1989 In addition, the sera of untreated TB mice contained levels of IL-6 which paralleled the extent of tumor burden (serum IL-6 in day 30 MCA 106 TB mice = 420 HGF U/ml). Terbium 35-37 interleukin 6 Mus musculus 119-123 2499626-14 1989 Although the exact role of IL-6 in TB animals remains to be elucidated, its known pleotrophic immune and metabolic effects may be important in the host response to malignancy. Terbium 35-37 interleukin 6 Mus musculus 27-31 2729996-1 1989 The emission intensity of the fluorescent lanthanide, terbium, is shown to be enhanced upon binding to chicken cystatin. Terbium 54-61 cystatin C Gallus gallus 111-119 2729996-4 1989 Calcium displaces the terbium from cystatin as judged by the decrease of terbium fluorescence in competition titrations. Terbium 22-29 cystatin C Gallus gallus 35-43 2729996-4 1989 Calcium displaces the terbium from cystatin as judged by the decrease of terbium fluorescence in competition titrations. Terbium 73-80 cystatin C Gallus gallus 35-43 2729996-5 1989 Similar titrations with magnesium or strontium demonstrate that the metal binding site of cystatin exhibits specificity for calcium or terbium. Terbium 135-142 cystatin C Gallus gallus 90-98 2667397-1 1989 Bovine serum albumin was labelled with a terbium complex by means of a reagent prepared from diethylenetriaminepentaacetic acid or diethylenetriaminepentaphosphonic acid and p-aminosalicylic acid. Terbium 41-48 albumin Homo sapiens 7-20 2716304-5 1989 Tumor resection reversed the heightened macrophage activity as LPS-induced levels of TNF secreted by macrophages from resected TB rats were not different from those of sham-operated NTB control rats. Terbium 127-129 tumor necrosis factor-like Rattus norvegicus 85-88 2716304-6 1989 TB rats had serum levels of TNF activity following an iv bolus of 10 mg/kg LPS greater than those of NTB rats (P less than 0.05). Terbium 0-2 tumor necrosis factor-like Rattus norvegicus 28-31 2566905-4 1989 Terbium (III) inhibition of transglutaminase-catalyzed putrescine incorporation into casein was not reversed by the presence of 10-200 fold molar excess of calcium ions (Ki for Tb(III) = 60 microM). Terbium 0-7 protein-glutamine gamma-glutamyltransferase 2 Cavia porcellus 28-44 2566905-4 1989 Terbium (III) inhibition of transglutaminase-catalyzed putrescine incorporation into casein was not reversed by the presence of 10-200 fold molar excess of calcium ions (Ki for Tb(III) = 60 microM). Terbium 177-179 protein-glutamine gamma-glutamyltransferase 2 Cavia porcellus 28-44 2564774-3 1989 Factor XIIIa formed by thrombin or trypsin in the presence of 40 microM-Tb(III) ions, however, was indistinguishable from Factor XIIIa formed in the presence of 2-5 mM-Ca(II) ions with respect to molecular mass and transglutaminase activity. Terbium 72-75 coagulation factor XIII A chain Homo sapiens 0-12 16031246-0 1986 MAF takes over TB scheme--a reply. Terbium 15-17 MAF bZIP transcription factor Homo sapiens 0-3 2506411-3 1989 Moreover, a strict relationship between Tac antigen expression and ability of exogenous IL-2 to enhance bulk culture cell proliferation was observed in Dis-TB patients. Terbium 156-158 interleukin 2 receptor subunit alpha Homo sapiens 40-51 2506411-3 1989 Moreover, a strict relationship between Tac antigen expression and ability of exogenous IL-2 to enhance bulk culture cell proliferation was observed in Dis-TB patients. Terbium 156-158 interleukin 2 Homo sapiens 88-92 3182830-3 1988 The combined study of direct calcium binding, modification of tryptophan fluorescence properties upon calcium binding, and terbium titration allows some discrimination among proposed mechanisms of cation binding to calmodulin. Terbium 123-130 calmodulin 1 Homo sapiens 215-225 2842452-0 1988 Interactions of spin-labeled calmodulin with trifluoperazine and phosphodiesterase in the presence of Ca(II), Cd(II), La(III), Tb(III), and Lu(III). Terbium 127-129 calmodulin Bos taurus 29-39 3407414-5 1988 Repeated (4 days) treatment with TB provoked an induction of HBO, AH, and EMND accompanied by an increase of NADPH-Cyt-C reductase and cytochrome P-450, hem and microsomal protein content. Terbium 33-35 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 135-151 3470740-1 1987 The fluorescence decay of the rare earth terbium when bound to the protein calmodulin changes from a simple exponential decay to a complex nonexponential decay as the temperature is lowered below 200 K. We have fit the observed decay curves by assuming that the terbium emission is a forced electric dipole transition and proteins have a distribution of continuous conformational states. Terbium 41-48 calmodulin 1 Homo sapiens 75-85 3470740-1 1987 The fluorescence decay of the rare earth terbium when bound to the protein calmodulin changes from a simple exponential decay to a complex nonexponential decay as the temperature is lowered below 200 K. We have fit the observed decay curves by assuming that the terbium emission is a forced electric dipole transition and proteins have a distribution of continuous conformational states. Terbium 262-269 calmodulin 1 Homo sapiens 75-85 3797845-5 1986 During increases in Tb in both control and vagotomized pigeons, fR, PaO2, pHa, heart rate and oxygen consumption increased, and PaCO2 decreased. Terbium 20-22 lamin B receptor Homo sapiens 74-77 3651471-11 1987 Terbium increased the intrinsic fluorescence of calsequestrin 2-fold, and increased the alpha-helical content of calsequestrin from 16 to 33%. Terbium 0-7 calsequestrin-2 Oryctolagus cuniculus 48-63 3626536-5 1987 TTR, TF, and RBP correlated significantly with TB and NTB VIS nitrogen and TB CAR nitrogen. Terbium 47-49 transthyretin Rattus norvegicus 0-3 3626536-5 1987 TTR, TF, and RBP correlated significantly with TB and NTB VIS nitrogen and TB CAR nitrogen. Terbium 47-49 transferrin Rattus norvegicus 5-7 3626536-5 1987 TTR, TF, and RBP correlated significantly with TB and NTB VIS nitrogen and TB CAR nitrogen. Terbium 47-49 retinol binding protein 4 Rattus norvegicus 13-16 3626536-6 1987 The correlation of NTB VIS nitrogen with TTR, TF, and RBP (r range = 0.70-0.85, P less than 0.001) was higher than for TB rats (r range = 0.53-0.57, P less than 0.005). Terbium 20-22 transthyretin Rattus norvegicus 41-44 3626536-6 1987 The correlation of NTB VIS nitrogen with TTR, TF, and RBP (r range = 0.70-0.85, P less than 0.001) was higher than for TB rats (r range = 0.53-0.57, P less than 0.005). Terbium 20-22 retinol binding protein 4 Rattus norvegicus 54-57 3792310-0 1986 Kinetics of cadmium and terbium dissociation from calmodulin and its tryptic fragments. Terbium 24-31 calmodulin Bos taurus 50-60 3792310-1 1986 The kinetics of cadmium and terbium dissociation from bovine testis calmodulin and its tryptic fragments have been studied by stopped-flow fluorescence methods, using the calcium indicator Quin 2. Terbium 28-35 calmodulin Bos taurus 68-78 16031228-0 1986 MAF takes over TB scheme--a reply. Terbium 15-17 MAF bZIP transcription factor Homo sapiens 0-3 3160702-0 1985 Localization of a fibrinogen calcium binding site between gamma-subunit positions 311 and 336 by terbium fluorescence. Terbium 97-104 fibrinogen beta chain Homo sapiens 18-28 16031310-0 1986 MAF takes over TB scheme. Terbium 15-17 MAF bZIP transcription factor Homo sapiens 0-3 9940058-0 1986 Spin-glass transition in amorphous Tb-Si films. Terbium 35-37 spindlin 1 Homo sapiens 0-4 3160702-3 1985 Terbium (Tb3+) competitively inhibited 45Ca2+ binding to fibrinogen during equilibrium dialysis, accelerated fibrin polymerization, and limited fibrinogen fragment D digestion by plasmin. Terbium 0-7 fibrinogen beta chain Homo sapiens 57-67 3160702-3 1985 Terbium (Tb3+) competitively inhibited 45Ca2+ binding to fibrinogen during equilibrium dialysis, accelerated fibrin polymerization, and limited fibrinogen fragment D digestion by plasmin. Terbium 0-7 fibrinogen beta chain Homo sapiens 144-154 3016042-4 1985 During torpor Ea1 increased in a linear manner as Tb was lowered. Terbium 50-52 potassium voltage-gated channel subfamily A member 1 Homo sapiens 14-17 6868057-6 1983 ABO blood group typing results indicate that blood group "O" may afford protection against TB. Terbium 91-93 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Homo sapiens 0-15 6469988-0 1984 Conformational changes induced by zinc and terbium binding to native bovine alpha-lactalbumin and calcium-free alpha-lactalbumin. Terbium 43-50 lactalbumin alpha Bos taurus 76-93 6469988-0 1984 Conformational changes induced by zinc and terbium binding to native bovine alpha-lactalbumin and calcium-free alpha-lactalbumin. Terbium 43-50 lactalbumin alpha Bos taurus 111-128 6469988-1 1984 Terbium at submillimolar concentrations appears to bind to the calcium site of apo bovine alpha-lactalbumin and stabilizes the N conformation (fluorescence criterion; Kronman, M. J., Sinha, S., and Brew, K. (1981) J. Biol. Terbium 0-7 lactalbumin alpha Bos taurus 90-107 6469988-11 1984 Millimolar concentrations of Zn2+ induce a time-dependent conformational change in both calcium-free and calcium-liganded alpha-lactalbumin to produce an "expanded A-like state" comparable to that seen with terbium at similar concentrations. Terbium 207-214 lactalbumin alpha Bos taurus 122-139 6716357-0 1984 Tuberculosis in a developing country: experiences of the TB service at BMH, Dharan. Terbium 57-59 bleomycin hydrolase Homo sapiens 71-74 6389227-2 1984 Terbium (Tb3+), an ion of the lanthanide series that has been used as a fluorescent probe for calcium (Ca2+) binding sites in proteins, binds to the proteins in both solubilized and purified human placental insulin receptor preparations. Terbium 0-7 insulin receptor Homo sapiens 207-223 6334140-4 1984 In cocultures consisting of NS and TBS (1:1), TCGF production by NS was markedly suppressed. Terbium 35-38 interleukin 2 Mus musculus 46-50 6334140-7 1984 TCGF production by TBS could be completely restored by depletion of both phagocytes and Lyt 2+ T cells. Terbium 19-22 interleukin 2 Mus musculus 0-4 6334140-9 1984 It is concluded that suppression of TCGF production in vitro by TBS is mediated by phagocyte-released PG and by Lyt 2+ T lymphocytes. Terbium 64-67 interleukin 2 Mus musculus 36-40 6726222-0 1984 Spectroscopic studies on the binding of iron, terbium, and zinc by apoferritin. Terbium 46-53 ferritin heavy chain 1 Homo sapiens 67-78 6149075-0 1984 Terbium binding to rat brain acetylcholinesterase. Terbium 0-7 acetylcholinesterase Rattus norvegicus 29-49 6149075-3 1984 Terbium was studied as a fluorescence probe of Ca2+ binding sites in partially purified AChE from whole rat brain. Terbium 0-7 acetylcholinesterase Rattus norvegicus 88-92 6838970-1 1983 We have used anomalous small-angle x-ray scattering as a structural probe for solutions of rabbit parvalbumin labeled with terbium. Terbium 123-130 parvalbumin alpha Oryctolagus cuniculus 98-109 921926-0 1977 Energy transfer between terbium and iron bound to transferrin: reinvestigation of the distance between metal-binding sites. Terbium 24-31 transferrin Homo sapiens 50-61 7295641-0 1981 Distance between metal-binding sites in transferrin: energy transfer from bound terbium (III) to iron (III) or manganese (III). Terbium 80-87 transferrin Homo sapiens 40-51 7295641-1 1981 The distance between the two metal-binding sites of human serum transferrin has been studied by observing energy transfer between an excited terbium ion bound at one site and a ferric (or manganic) ion bound at the other site of the same transferrin molecule. Terbium 141-148 transferrin Homo sapiens 64-75 6295470-6 1982 Discontinuities in the slope of Arrhenius plots for TB were seen at 34 and 66 degrees C (yeast MSL tRNA), 37 and 60 degrees C (E. coli MSL 5S RNA), 37 and 57 degrees C (yeast MSL 5S RNA), and 36 and 54 degrees C (wheat germ MSL 5S RNA). Terbium 52-54 mRNA splicing protein MSL5 Saccharomyces cerevisiae S288C 135-140 6276400-2 1982 Terbium, a trivalent lanthanide, effectively substituted for Ca2+ in calmodulin as judged by several criteria: intrinsic fluorescence spectra, altered mobilities on polyacrylamide gel electrophoresis, formation of a stable complex with troponin I or calcineurin, and stimulation of phosphodiesterase. Terbium 0-7 calmodulin 1 Homo sapiens 69-79 6117485-4 1981 Some somatostatin-related peptides, e.g., desAA 1,2,4,5,12,13 [D-Trp8]-somatostatin (ODT8-SS), act within the brain to prevent bombesin-induced reduction of VO2 and Tb. Terbium 165-167 somatostatin Rattus norvegicus 5-17 6117485-4 1981 Some somatostatin-related peptides, e.g., desAA 1,2,4,5,12,13 [D-Trp8]-somatostatin (ODT8-SS), act within the brain to prevent bombesin-induced reduction of VO2 and Tb. Terbium 165-167 somatostatin Rattus norvegicus 71-83 6912588-0 1980 AKAP nurses in primary health care TB control program. Terbium 35-37 A-kinase anchoring protein 1 Homo sapiens 0-4 35127-1 1978 It was determined that in the serum of TB patients, the factor (beta-lipoprotein) was present, lowering/modulating the ability of T lymphocyte rosette formation with SRBC. Terbium 39-41 caveolae associated protein 3 Homo sapiens 166-170 921926-1 1977 The addition of trivalent iron, gallium, and terbium ions to the metal binding sites of human transferrin has been investigated by fluorescence and spectrophotometric measurements. Terbium 45-52 transferrin Homo sapiens 94-105 921926-3 1977 The subsequent addition of terbium leads to the binding of terbium ions to the vacant sites on monoferric transferrin molecules, and observations of the intensity of terbium fluorescence from such samples provides clear evidence of transfer of excitation energy from the terbium site to the iron site. Terbium 27-34 transferrin Homo sapiens 106-117 921926-3 1977 The subsequent addition of terbium leads to the binding of terbium ions to the vacant sites on monoferric transferrin molecules, and observations of the intensity of terbium fluorescence from such samples provides clear evidence of transfer of excitation energy from the terbium site to the iron site. Terbium 59-66 transferrin Homo sapiens 106-117 921926-3 1977 The subsequent addition of terbium leads to the binding of terbium ions to the vacant sites on monoferric transferrin molecules, and observations of the intensity of terbium fluorescence from such samples provides clear evidence of transfer of excitation energy from the terbium site to the iron site. Terbium 59-66 transferrin Homo sapiens 106-117 921926-3 1977 The subsequent addition of terbium leads to the binding of terbium ions to the vacant sites on monoferric transferrin molecules, and observations of the intensity of terbium fluorescence from such samples provides clear evidence of transfer of excitation energy from the terbium site to the iron site. Terbium 59-66 transferrin Homo sapiens 106-117 1151070-1 1975 This preliminary study was undertaken to investigate the chemical nature of the Thy-1.2 antigen expressed on the murine cell line S-49.1 TB-2-3 (S-49). Terbium 137-139 thymus cell antigen 1, theta Mus musculus 80-87 851545-6 1977 From the positional distribution of 14C-labeled fatty acid and the change in the doubly labeled molecular species of phospholipids, it was concluded that tb degradation of dilinoleoylglycerophosphocholine and that of phosphatidylethanolamine could be accounted for by the action of phospholipase A1, while the degradation of dipalmitoylglycerophosphocholine proceeded through the action of phospholipase A2. Terbium 154-156 phospholipase A2 group IB Rattus norvegicus 390-406 931853-8 1976 Our results also support the concept that Tb may be the regulated variable of the thermoregulatory system, since we obtained a very significant and uniform correlation between Esk and delta Tb at the three Ta and the two work intensities which were studied. Terbium 42-44 TTK protein kinase Homo sapiens 176-179 826080-2 1976 The unstable haemoglobin, Tb Torino (alpha43(CD1)Phe replaced by Val), has been found for the second time in a family from the Treviso region of Italy. Terbium 26-28 CD1c molecule Homo sapiens 45-48 1158898-18 1975 These observations, particularly those made in the course of characterizine P"2, have led to the conclusion that cleavage of the peptide bond connecting the TA and TB portions of the prothrombin molecule (or its derivatives) produces a serine active center and, hence, a molecule possessing thrombin activity. Terbium 164-166 coagulation factor II, thrombin Homo sapiens 183-194 1158898-18 1975 These observations, particularly those made in the course of characterizine P"2, have led to the conclusion that cleavage of the peptide bond connecting the TA and TB portions of the prothrombin molecule (or its derivatives) produces a serine active center and, hence, a molecule possessing thrombin activity. Terbium 164-166 coagulation factor II, thrombin Homo sapiens 186-194 1155384-2 1975 The method is based on the discovery by C. K. Luk that the fluorescence of terbium ion (Tb-3+) is enhanced enormously when it binds to an empty Fe-3+ binding site of transferrin. Terbium 75-82 transferrin Homo sapiens 166-177 5981380-0 1966 Physicians can aid early TB examinations required for school personnel by Sept 1. Terbium 25-27 septin 1 Homo sapiens 74-80 4811068-0 1974 Optical activity of terbium ions bound to transferrin and conalbumin studied by circular polarization of luminescence. Terbium 20-27 transferrin Homo sapiens 42-53 33554369-7 2021 Compared with SC-SL, TB-SL MRF showed in experiments greater robustness against severe B1 inhomogeneities and in Bloch simulations greater robustness against B1 and B0 . Terbium 21-23 immunoglobulin kappa variable 7-3 (pseudogene) Homo sapiens 158-167 34041910-5 2021 We demonstrated specific miR-21 detection with 80 fM limit of detection and multiplexing capability with FRET from a Tb complex to different QDs. Terbium 117-119 microRNA 21 Homo sapiens 25-31 34046917-10 2021 WHAT IS NEW AND CONCLUSION: Based on a 1:4 individual matched case-control study, possessing the CC genotype at rs2011404 of the UGT1A4 gene reduces the risk of moderate or severe liver injury in Eastern Chinese Han patients receiving anti-TB treatment. Terbium 240-242 UDP glucuronosyltransferase family 1 member A4 Homo sapiens 129-135 34009424-12 2021 In addition, Tb.Th (p < 0.05) and the mRNA gene expression levels of COX-2 and RANKL (p < 0.05) were decreased. Terbium 13-15 TNF superfamily member 11 Rattus norvegicus 79-84 34034718-10 2021 Bone Dkk-1 was positively correlated with serum ionised calcium, serum Dkk-1, BMD, BV/TV, trabecular thickness, Tb.N, maximum compressive force, yield strength, and Young"s modulus (r = 0.38, 0.809, 0.293, 0.293, 0.228, 0.318, 0.352, 0.315, and 0.266, respectively, P < 0.05) and negatively correlated with age and Tb.Sp (r = - 0.56 and - 0.38, respectively, P < 0.05). Terbium 112-114 dickkopf WNT signaling pathway inhibitor 1 Homo sapiens 5-10 34038711-3 2021 Using mice, we now identify POA neurons expressing bombesin-like receptor 3 (POABRS3) as a population whose activation increased Tb; inversely, acute inhibition of these neurons reduced Tb. Terbium 129-131 bombesin-like receptor 3 Mus musculus 51-75 34038711-3 2021 Using mice, we now identify POA neurons expressing bombesin-like receptor 3 (POABRS3) as a population whose activation increased Tb; inversely, acute inhibition of these neurons reduced Tb. Terbium 186-188 bombesin-like receptor 3 Mus musculus 51-75 33730443-11 2021 Finally, delayed salivary melatonin and Tb phases were observed in MTNR1B G-allele carriers with advanced glaucoma. Terbium 40-42 melatonin receptor 1B Homo sapiens 67-73 34058448-7 2021 RESULTS: Recessive genetic models of NOD2 802C > T SNP with TT genotype and AA genotype of NOD2 2105G > A SNP were significantly associated with increased TB risk in PTB patients and HHC compared with HC. Terbium 155-157 nucleotide binding oligomerization domain containing 2 Homo sapiens 37-41 34058448-7 2021 RESULTS: Recessive genetic models of NOD2 802C > T SNP with TT genotype and AA genotype of NOD2 2105G > A SNP were significantly associated with increased TB risk in PTB patients and HHC compared with HC. Terbium 155-157 nucleotide binding oligomerization domain containing 2 Homo sapiens 91-95 33903099-11 2021 Therefore, CC214-2 and related mTOR kinase inhibitors may be more effective candidates for HDT than rapamycin analogs and may have the potential to shorten the duration of TB treatment. Terbium 172-174 mechanistic target of rapamycin kinase Mus musculus 31-35 33185014-5 2021 A good linear relationship between the MET concentration and enhanced emission intensity of Tb-phen-AgNPs system was observed in the range of (0.75-3.7) x 10-6 M under optimum conditions. Terbium 92-94 SAFB like transcription modulator Homo sapiens 39-42 33507518-8 2021 Postoperatively, the RYGB and SG-TB groups had significantly higher GLP-1 levels and lower insulin levels than the SG group. Terbium 33-35 glucagon Rattus norvegicus 68-73 33581127-13 2021 Moreover, in vivo experiments showed that in ovariectomized rats, silencing of miR-935 significantly reduced BMD, BV/TV, Tb.N, Tb.Th and increased Tb.Sp. Terbium 121-123 microRNA 935 Rattus norvegicus 79-86 33581127-13 2021 Moreover, in vivo experiments showed that in ovariectomized rats, silencing of miR-935 significantly reduced BMD, BV/TV, Tb.N, Tb.Th and increased Tb.Sp. Terbium 127-129 microRNA 935 Rattus norvegicus 79-86 33922073-2 2021 Herein, we synthesized ultra-small nanoparticle chelated with Terbium (Tb) as a nanoscintillator and 5-(4-carboxyphenyl succinimide ester)-10,15,20-triphenyl porphyrin (P1) as a photosensitizer (AGuIX@Tb-P1). Terbium 71-73 TNF receptor superfamily member 1A Homo sapiens 201-206 33900343-9 2021 The network pharmacology analysis based on these absorbed components was performed and, along with experimental evidence, it revealed that the ERBB, PI3K-Akt, and MAPK signaling pathways may be involved in the anti-tumor effect of TB-TF on HCC. Terbium 231-233 epidermal growth factor receptor Mus musculus 143-147 33900343-9 2021 The network pharmacology analysis based on these absorbed components was performed and, along with experimental evidence, it revealed that the ERBB, PI3K-Akt, and MAPK signaling pathways may be involved in the anti-tumor effect of TB-TF on HCC. Terbium 231-233 thymoma viral proto-oncogene 1 Mus musculus 154-157 33997311-2 2021 Methods: We examined the levels of TIMP-1, -2, -3 and -4 in pulmonary tuberculosis alone (TB) or TB-DM at baseline and after ATT. Terbium 90-92 TIMP metallopeptidase inhibitor 1 Homo sapiens 35-56 33997311-3 2021 Results: TIMP-1, -3 and -4 were significantly increased in TB-DM compared to TB at baseline and after ATT. Terbium 59-61 TIMP metallopeptidase inhibitor 1 Homo sapiens 9-26 33922073-6 2021 We demonstrated that the AGuIX@Tb-P1 design was consistent with X-ray photon energy transfer from Terbium to P1. Terbium 98-105 TNF receptor superfamily member 1A Homo sapiens 31-36 33997311-4 2021 ATT resulted in a significant reduction in TIMP-2 and -3 levels and a significant increase in TIMP-1 in both TB and TB-DM. Terbium 109-111 TIMP metallopeptidase inhibitor 1 Homo sapiens 94-100 33832532-13 2021 Postn-/- mice also showed lower trabecular bone parameters such as BV/TV, vBMD, Tb.Th, and Tb.N and high Tb. Terbium 80-82 periostin, osteoblast specific factor Mus musculus 0-5 33997311-5 2021 TIMP-1, -3 and -4 were also significantly increased in TB-DM individuals with bilateral, cavitary disease and also exhibited a positive relationship with bacterial burden in TB-DM and HbA1c in all TB individuals. Terbium 55-57 TIMP metallopeptidase inhibitor 1 Homo sapiens 0-17 33997311-5 2021 TIMP-1, -3 and -4 were also significantly increased in TB-DM individuals with bilateral, cavitary disease and also exhibited a positive relationship with bacterial burden in TB-DM and HbA1c in all TB individuals. Terbium 174-176 TIMP metallopeptidase inhibitor 1 Homo sapiens 0-17 33997311-5 2021 TIMP-1, -3 and -4 were also significantly increased in TB-DM individuals with bilateral, cavitary disease and also exhibited a positive relationship with bacterial burden in TB-DM and HbA1c in all TB individuals. Terbium 174-176 TIMP metallopeptidase inhibitor 1 Homo sapiens 0-17 33997311-6 2021 Within the TB-DM group, those known to be diabetic before incident TB (KDM) exhibited higher levels of TIMP-1, -2, -3 and -4 at baseline and TIMP-2 at post-treatment compared to those newly diagnosed with DM (NDM). Terbium 11-13 TIMP metallopeptidase inhibitor 1 Homo sapiens 103-124 33997311-6 2021 Within the TB-DM group, those known to be diabetic before incident TB (KDM) exhibited higher levels of TIMP-1, -2, -3 and -4 at baseline and TIMP-2 at post-treatment compared to those newly diagnosed with DM (NDM). Terbium 11-13 TIMP metallopeptidase inhibitor 2 Homo sapiens 141-147 33997311-8 2021 Conclusions: TIMP levels were elevated in TB-DM, associated with disease severity and bacterial burden, correlated with HbA1c levels and modulated by duration of DM and metformin treatment. Terbium 42-44 TIMP metallopeptidase inhibitor 1 Homo sapiens 13-17 33887214-8 2021 Animals showed TB reactivation suggesting that dMtb may exploit ASCs for disease reactivation.. Terbium 15-17 mtb Drosophila melanogaster 47-51 33826292-6 2021 The combination of cerium (C), molybdenum (M), europium (E), and terbium (T) results in a sheet-like CMET perovskite obeying hexagonal geometry. Terbium 65-72 MET proto-oncogene, receptor tyrosine kinase Homo sapiens 101-105 33832532-13 2021 Postn-/- mice also showed lower trabecular bone parameters such as BV/TV, vBMD, Tb.Th, and Tb.N and high Tb. Terbium 91-93 periostin, osteoblast specific factor Mus musculus 0-5 33832532-13 2021 Postn-/- mice also showed lower trabecular bone parameters such as BV/TV, vBMD, Tb.Th, and Tb.N and high Tb. Terbium 91-93 periostin, osteoblast specific factor Mus musculus 0-5 33831998-12 2021 Bcl-2 staining limited to the outermost layer of the proliferation is more likely to be found in TB. Terbium 97-99 BCL2 apoptosis regulator Homo sapiens 0-5 33317988-6 2021 RESULTS: IL-1RA, IFN-gamma, CXCL10/IP-10, and CCL4/MIP-1beta levels were higher in the active TB group than in the LTBI group in QFT-GIT antigen (GIT Ag) tubes. Terbium 94-96 C-C motif chemokine ligand 4 Homo sapiens 46-50 33317988-6 2021 RESULTS: IL-1RA, IFN-gamma, CXCL10/IP-10, and CCL4/MIP-1beta levels were higher in the active TB group than in the LTBI group in QFT-GIT antigen (GIT Ag) tubes. Terbium 94-96 C-C motif chemokine ligand 4 Homo sapiens 51-60 33317988-8 2021 In Nil tubes, CCL5/RANTES, TNF-alpha, PDGF-BB, and IL-2 levels were significantly higher in the active TB group. Terbium 103-105 C-C motif chemokine ligand 5 Homo sapiens 14-18 33317988-8 2021 In Nil tubes, CCL5/RANTES, TNF-alpha, PDGF-BB, and IL-2 levels were significantly higher in the active TB group. Terbium 103-105 C-C motif chemokine ligand 5 Homo sapiens 19-25 33317988-8 2021 In Nil tubes, CCL5/RANTES, TNF-alpha, PDGF-BB, and IL-2 levels were significantly higher in the active TB group. Terbium 103-105 tumor necrosis factor Homo sapiens 27-36 33317988-8 2021 In Nil tubes, CCL5/RANTES, TNF-alpha, PDGF-BB, and IL-2 levels were significantly higher in the active TB group. Terbium 103-105 interleukin 2 Homo sapiens 51-55 33317988-11 2021 CONCLUSIONS: IL-1RA level in the QFT-GIT supernatant can be a good marker for discriminating active TB from LTBI. Terbium 100-102 interleukin 1 receptor antagonist Homo sapiens 13-19 33828558-11 2021 After 10 weeks of TB treatment, there was reversion in the observed functional impairment in total MAIT cells, with increases in CD107a (p = 0.020) and IFNgamma (p = 0.010) expression. Terbium 18-20 lysosomal associated membrane protein 1 Homo sapiens 129-135 32808146-11 2021 When compared with the control group, the expression of RANKL was significantly reduced by 40.0% in periodontitis in rats treated with TB-PDT for 15 days (P < 0.01). Terbium 135-137 TNF superfamily member 11 Rattus norvegicus 56-61 32808146-12 2021 The expression of OPG was increased in the PDT group with TB-PDT for 15 days, when compared with the control group (P < 0.05). Terbium 58-60 TNF receptor superfamily member 11B Rattus norvegicus 18-21 32808146-13 2021 TB-PDT treatment significantly reverses the abnormal expression of RANKL and OPG in periodontitis in rats. Terbium 0-2 TNF superfamily member 11 Rattus norvegicus 67-72 32808146-13 2021 TB-PDT treatment significantly reverses the abnormal expression of RANKL and OPG in periodontitis in rats. Terbium 0-2 TNF receptor superfamily member 11B Rattus norvegicus 77-80 33828558-11 2021 After 10 weeks of TB treatment, there was reversion in the observed functional impairment in total MAIT cells, with increases in CD107a (p = 0.020) and IFNgamma (p = 0.010) expression. Terbium 18-20 interferon gamma Homo sapiens 152-160 33740106-7 2021 Combined with fine-mapping and GWAS-eQTL colocalization analyses, our results suggested that locus 1p13.2 (including PTPN22, MAGI3, PHTF1, and RSBN1) was an important region to regulate TB-BMD and RA simultaneously. Terbium 186-188 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 117-123 33753877-2 2021 The objectives of our study were to determine whether the single-nucleotide polymorphism (SNPs) of MASP2 and the gene-tea drinking interaction were associated with the susceptibility to TB. Terbium 186-188 MBL associated serine protease 2 Homo sapiens 99-104 33753877-9 2021 Our finding indicated that the SNPs (rs12711521 and rs7548659) of MASP2 were associated with the susceptibility to TB. Terbium 115-117 MBL associated serine protease 2 Homo sapiens 66-71 33744856-4 2021 T-SPOT.TB was used to detect the number of cells secreting Interferon gamma. Terbium 7-9 interferon gamma Homo sapiens 59-75 33740106-7 2021 Combined with fine-mapping and GWAS-eQTL colocalization analyses, our results suggested that locus 1p13.2 (including PTPN22, MAGI3, PHTF1, and RSBN1) was an important region to regulate TB-BMD and RA simultaneously. Terbium 186-188 membrane associated guanylate kinase, WW and PDZ domain containing 3 Homo sapiens 125-130 33740106-7 2021 Combined with fine-mapping and GWAS-eQTL colocalization analyses, our results suggested that locus 1p13.2 (including PTPN22, MAGI3, PHTF1, and RSBN1) was an important region to regulate TB-BMD and RA simultaneously. Terbium 186-188 putative homeodomain transcription factor 1 Homo sapiens 132-137 33740106-7 2021 Combined with fine-mapping and GWAS-eQTL colocalization analyses, our results suggested that locus 1p13.2 (including PTPN22, MAGI3, PHTF1, and RSBN1) was an important region to regulate TB-BMD and RA simultaneously. Terbium 186-188 round spermatid basic protein 1 Homo sapiens 143-148 33869073-9 2021 After anti-TB treatment, IFN-gamma responses to the MTBK antigen were significantly reduced, and strong TNF-alpha responses at diagnosis were dramatically decreased. Terbium 11-13 interferon gamma Homo sapiens 25-34 33578038-7 2021 We demonstrated for the first time that transgelin plays an essential role in tumor vessel normalization, and thus, it impairs TB and metastasis. Terbium 127-129 transgelin Mus musculus 40-50 32678272-7 2021 Building on substantial evidence from animal models implicating CD153 as a mediator of host protection, our findings suggest it may play a similar role in humans and its measurement may be useful to evaluate TB vaccine efficacy. Terbium 208-210 TNF superfamily member 8 Homo sapiens 64-69 33672750-2 2021 It was found that, in contrast to the situation in amorphous Gd-Co ribbons, the dependence of Tc on Tb content and the maximum -DeltaSm vs. Tc -2/3 plots in Tb-Co binary amorphous alloys do not follow a linear relationship, both of which are supposed to be closely related to the non-linear compositional dependence of Tb-Co interaction due to the existence of orbital momentum in Tb. Terbium 157-159 transcobalamin 2 Homo sapiens 140-147 33672750-2 2021 It was found that, in contrast to the situation in amorphous Gd-Co ribbons, the dependence of Tc on Tb content and the maximum -DeltaSm vs. Tc -2/3 plots in Tb-Co binary amorphous alloys do not follow a linear relationship, both of which are supposed to be closely related to the non-linear compositional dependence of Tb-Co interaction due to the existence of orbital momentum in Tb. Terbium 157-159 transcobalamin 2 Homo sapiens 140-147 33672750-2 2021 It was found that, in contrast to the situation in amorphous Gd-Co ribbons, the dependence of Tc on Tb content and the maximum -DeltaSm vs. Tc -2/3 plots in Tb-Co binary amorphous alloys do not follow a linear relationship, both of which are supposed to be closely related to the non-linear compositional dependence of Tb-Co interaction due to the existence of orbital momentum in Tb. Terbium 157-159 transcobalamin 2 Homo sapiens 140-147 33796106-6 2021 In general, males showed higher interferon-gamma responses to TB antigens ESAT-6 and CFP-10, whilst females had stronger tuberculin responses in those with sputum smear- and culture-positive tuberculosis, but smaller responses in those who were screened for tuberculosis and who did not develop disease. Terbium 62-64 interferon gamma Homo sapiens 32-48 33440261-4 2021 METHODS: In the IDEA-TB study we enrolled HIV + adult patients attending 3 DREAM Centers in Kenya who were suspected of having TB. Terbium 127-129 potassium voltage-gated channel interacting protein 3 Homo sapiens 75-80 33440261-12 2021 Malnutrition and elevated HS-CRP were associated with TB (AOR 2.2[1.23-3.90] and 6.8[3.75-12.60]). Terbium 54-56 C-reactive protein Homo sapiens 29-32 33440261-14 2021 No single factor was associated with mortality, only the combination of malnutrition and elevated HS-CRP was highly predictive of death (OR 9.8[1.88-50.95]); the association was stronger in TB- patients (33.3% vs 1.0%, OR 47.6 [7.03-322.23]). Terbium 190-192 C-reactive protein Homo sapiens 101-104 33584652-10 2020 Interestingly, in exploratory analysis, LTBI+ TB progressors had significantly higher levels of IL1beta, IL-6 and IL-13 in multivariable models compared to LTBI+ non-progressors. Terbium 41-43 interleukin 1 alpha Homo sapiens 96-103 33598569-6 2021 TB prevention in silicosis patients is essential and include active surveillance of the workers, periodic chest X-rays, tuberculin skin test or interferon-gamma releasing assay testing, and, importantly, adoption of measures to reduce the exposure to silica dust. Terbium 0-2 interferon gamma Homo sapiens 144-160 32734457-8 2021 PSMA-TB detected significantly more PCa and csPCa than TRUS-GB in the TRUS controls (PCa, 21/25 (84.0%) vs 19/60 (31.6%), P < 0.01; csPCa, 20/25 (80.0%) vs 15/60 (25.0%), P < 0.01). Terbium 5-7 folate hydrolase 1 Homo sapiens 0-4 32734457-10 2021 No haematuria, urinary retention or pelvic infection was observed after PSMA-TB compare with TRUS-GB. Terbium 77-79 folate hydrolase 1 Homo sapiens 72-76 32577812-11 2021 High TB grade (Bd3) was significantly associated with shorter CSS (P = 0.0001), but it lost prognostic value at multivariate analysis. Terbium 5-7 defensin beta 103B Homo sapiens 15-18 33571149-2 2021 We aimed to find out the diagnostic yield and accuracy of chemokine CXCL12 (SDF-1a) levels in diagnosing active TB (aTB) and making a differential diagnosis from other several infectious/non-infectious pulmonary conditions. Terbium 112-114 C-X-C motif chemokine ligand 12 Homo sapiens 68-74 33584591-0 2020 Low-Density Granulocytes Affect T-SPOT.TB Assay by Inhibiting the Production of Interferon-gamma in T Cells via PD-L1/PD-1 Pathway. Terbium 39-41 interferon gamma Homo sapiens 80-96 33584591-0 2020 Low-Density Granulocytes Affect T-SPOT.TB Assay by Inhibiting the Production of Interferon-gamma in T Cells via PD-L1/PD-1 Pathway. Terbium 39-41 CD274 molecule Homo sapiens 112-117 33584591-0 2020 Low-Density Granulocytes Affect T-SPOT.TB Assay by Inhibiting the Production of Interferon-gamma in T Cells via PD-L1/PD-1 Pathway. Terbium 39-41 programmed cell death 1 Homo sapiens 118-122 33584591-1 2020 Background: T-SPOT TB (T-SPOT) assay is widely used for detection of Mycobacterium tuberculosis infection that is based on the detection of M. tuberculosis-specific interferon-gamma-secreting T cells (ISCs) in peripheral blood mononuclear cells (PBMCs). Terbium 19-21 interferon gamma Homo sapiens 165-181 33584652-10 2020 Interestingly, in exploratory analysis, LTBI+ TB progressors had significantly higher levels of IL1beta, IL-6 and IL-13 in multivariable models compared to LTBI+ non-progressors. Terbium 41-43 interleukin 6 Homo sapiens 105-109 33584652-10 2020 Interestingly, in exploratory analysis, LTBI+ TB progressors had significantly higher levels of IL1beta, IL-6 and IL-13 in multivariable models compared to LTBI+ non-progressors. Terbium 41-43 interleukin 13 Homo sapiens 114-119 33410430-5 2021 However, in the presence of thiocholine (TCh), a thiol-containing compound hydrolyzed from acetylthiocholine (ATCh) by AChE, a stronger coordination interaction between Cu2+ and TCh occurred, resulting in the restoration of the fluorescence of GQD@Tb/GMP ICPs. Terbium 248-250 acetylcholinesterase Rattus norvegicus 119-123 33256982-8 2021 To test the activity of NADPH oxidase, we detected NADPH in MEM and CAZ/TB pre-cultivated activated PMNs, which showed that MEM and CAZ/TB modulates NETs formation through activation of NADHP oxidase by affecting the subunits of key enzymes. Terbium 72-74 2,4-dienoyl-CoA reductase 1 Homo sapiens 24-29 33397312-3 2021 This study estimates diagnostic efficacy of the interferon gamma release assay (IGRA: T-SPOT.TB) in TPE patients of different characteristics. Terbium 93-95 interferon gamma Homo sapiens 48-64 33256982-8 2021 To test the activity of NADPH oxidase, we detected NADPH in MEM and CAZ/TB pre-cultivated activated PMNs, which showed that MEM and CAZ/TB modulates NETs formation through activation of NADHP oxidase by affecting the subunits of key enzymes. Terbium 72-74 2,4-dienoyl-CoA reductase 1 Homo sapiens 51-56 33256982-8 2021 To test the activity of NADPH oxidase, we detected NADPH in MEM and CAZ/TB pre-cultivated activated PMNs, which showed that MEM and CAZ/TB modulates NETs formation through activation of NADHP oxidase by affecting the subunits of key enzymes. Terbium 136-138 2,4-dienoyl-CoA reductase 1 Homo sapiens 24-29 33256982-8 2021 To test the activity of NADPH oxidase, we detected NADPH in MEM and CAZ/TB pre-cultivated activated PMNs, which showed that MEM and CAZ/TB modulates NETs formation through activation of NADHP oxidase by affecting the subunits of key enzymes. Terbium 136-138 2,4-dienoyl-CoA reductase 1 Homo sapiens 51-56 33045524-8 2021 TB antigens induced the secretion of IL-1Ra in LTB+ subjects in the NGT, PDM and NDM groups, but not in the KDM group. Terbium 0-2 interleukin 1 receptor antagonist Homo sapiens 37-43 33045524-8 2021 TB antigens induced the secretion of IL-1Ra in LTB+ subjects in the NGT, PDM and NDM groups, but not in the KDM group. Terbium 0-2 lymphotoxin beta Homo sapiens 47-50 32965543-12 2021 CONCLUSION: Higher ZBTB7A expression in the tumor margin may contribute to the dissociation of tumor cells from the tumor mass to form TB by initiating EMT via EGFR-MEK-ERK and PI3K-AKT-mTOR pathway. Terbium 21-23 epidermal growth factor receptor Homo sapiens 160-164 32965543-12 2021 CONCLUSION: Higher ZBTB7A expression in the tumor margin may contribute to the dissociation of tumor cells from the tumor mass to form TB by initiating EMT via EGFR-MEK-ERK and PI3K-AKT-mTOR pathway. Terbium 21-23 mitogen-activated protein kinase kinase 7 Homo sapiens 165-168 32965543-12 2021 CONCLUSION: Higher ZBTB7A expression in the tumor margin may contribute to the dissociation of tumor cells from the tumor mass to form TB by initiating EMT via EGFR-MEK-ERK and PI3K-AKT-mTOR pathway. Terbium 21-23 mitogen-activated protein kinase 1 Homo sapiens 169-172 32965543-12 2021 CONCLUSION: Higher ZBTB7A expression in the tumor margin may contribute to the dissociation of tumor cells from the tumor mass to form TB by initiating EMT via EGFR-MEK-ERK and PI3K-AKT-mTOR pathway. Terbium 21-23 AKT serine/threonine kinase 1 Homo sapiens 182-185 32965543-12 2021 CONCLUSION: Higher ZBTB7A expression in the tumor margin may contribute to the dissociation of tumor cells from the tumor mass to form TB by initiating EMT via EGFR-MEK-ERK and PI3K-AKT-mTOR pathway. Terbium 21-23 mechanistic target of rapamycin kinase Homo sapiens 186-190 33384873-8 2021 Conclusions: It is necessary to check the expression of mRNA gene Treg, Treg, CD4+, and CD8+ with more samples to find the mean value that shows the protective value of further TB. Terbium 177-179 CD4 molecule Homo sapiens 78-81 32768732-2 2021 In this study, we reported that doping Terbium (III) ions (Tb3+) in self-activated luminescent nHAp via a facile hydrothermal reaction, using trisodium citrate (Cit3-), generates unique emission-tunable probes known as Cit/Tb-nHAp. Terbium 59-61 citron rho-interacting serine/threonine kinase Homo sapiens 161-164 32768732-3 2021 The morphology, crystal phase, and luminescence properties of these Cit/Tb-nHAp probes are studied in detail. Terbium 72-74 citron rho-interacting serine/threonine kinase Homo sapiens 68-71 32768732-7 2021 We also present in vitro data showing efficient cytoplasmic localization of transferrin conjugated Cit/Tb-nHAp into C6 glioma cells by fluorescence cell imaging. Terbium 103-105 transferrin Homo sapiens 76-87 32768732-8 2021 We have successfully engineered Cit/Tb-nHAp, a promising biocompatible agent for future in vitro and in vivo fluorescence bioimaging. Terbium 36-38 citron rho-interacting serine/threonine kinase Homo sapiens 32-35 33185878-2 2021 Secretion of tumor necrosis factor (TNF) has important protective and immune modulatory functions for immune responses during CNS-TB. Terbium 130-132 tumor necrosis factor Mus musculus 13-34 33185878-2 2021 Secretion of tumor necrosis factor (TNF) has important protective and immune modulatory functions for immune responses during CNS-TB. Terbium 130-132 tumor necrosis factor Mus musculus 36-39 32564647-4 2021 To more effectively identify promising Nrf2 activators through the inhibition of Keap1-Nrf2 PPI, a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET) assay was developed in this work by indirectly labeling the Keap1 Kelch domain protein with Tb-anti-His antibody as the donor and using, as the acceptor, fluorescein isothiocyanate (FITC)-labeled 9mer Nrf2 peptide amide, the same fluorescent probe that was used in an earlier fluorescence polarization (FP) assay. Terbium 266-268 NFE2 like bZIP transcription factor 2 Homo sapiens 39-43 32564647-4 2021 To more effectively identify promising Nrf2 activators through the inhibition of Keap1-Nrf2 PPI, a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET) assay was developed in this work by indirectly labeling the Keap1 Kelch domain protein with Tb-anti-His antibody as the donor and using, as the acceptor, fluorescein isothiocyanate (FITC)-labeled 9mer Nrf2 peptide amide, the same fluorescent probe that was used in an earlier fluorescence polarization (FP) assay. Terbium 266-268 kelch like ECH associated protein 1 Homo sapiens 81-86 32564647-4 2021 To more effectively identify promising Nrf2 activators through the inhibition of Keap1-Nrf2 PPI, a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET) assay was developed in this work by indirectly labeling the Keap1 Kelch domain protein with Tb-anti-His antibody as the donor and using, as the acceptor, fluorescein isothiocyanate (FITC)-labeled 9mer Nrf2 peptide amide, the same fluorescent probe that was used in an earlier fluorescence polarization (FP) assay. Terbium 266-268 kelch like ECH associated protein 1 Homo sapiens 234-239 33249336-6 2021 In participants with a household TB contact, HLA-A*66:01, -A*68:02 and -B*49:01 were associated with TST-negativity. Terbium 33-35 major histocompatibility complex, class I, A Homo sapiens 45-50 33382831-7 2020 A significant decrease over time could be observed in TB-IRIS patients during ART for anti -PR3 (p = 0.027), -lysozyme (p = 0.011), and -lactoferrin (p = 0.019). Terbium 54-56 proteinase 3 Homo sapiens 92-95 33382831-7 2020 A significant decrease over time could be observed in TB-IRIS patients during ART for anti -PR3 (p = 0.027), -lysozyme (p = 0.011), and -lactoferrin (p = 0.019). Terbium 54-56 lysozyme Homo sapiens 110-118 33376362-4 2020 TGH, located in the Sheka zone, is one of the remote areas and the KAP towards TB is unknown. Terbium 79-81 cyclin dependent kinase inhibitor 3 Homo sapiens 67-70 33376362-5 2020 Therefore, the current study was undertaken in TGH to assess the KAP towards TB. Terbium 77-79 carboxylesterase 1 Homo sapiens 47-50 33376362-5 2020 Therefore, the current study was undertaken in TGH to assess the KAP towards TB. Terbium 77-79 cyclin dependent kinase inhibitor 3 Homo sapiens 65-68 33437678-11 2020 High sensitivity of Determine TB-LAM Ag at lower CD4 count supports increased use in settings providing care to PLHIV, particularly with advanced HIV disease. Terbium 30-32 CD4 molecule Homo sapiens 49-52 33384873-8 2021 Conclusions: It is necessary to check the expression of mRNA gene Treg, Treg, CD4+, and CD8+ with more samples to find the mean value that shows the protective value of further TB. Terbium 177-179 CD8a molecule Homo sapiens 88-91 33381602-2 2020 In the present study, effort was made to find out the association of CCL2-2518 A>G and -362 G>C variants with susceptibility to TB in a population from North India. Terbium 128-130 C-C motif chemokine ligand 2 Homo sapiens 69-73 33301596-3 2021 Especially, Tb-complex is a bifunctional sensor for acac and Cd2+ , through luminescence "turn on" and "turn off", respectively. Terbium 12-14 acetyl-CoA carboxylase alpha Homo sapiens 52-56 33301596-3 2021 Especially, Tb-complex is a bifunctional sensor for acac and Cd2+ , through luminescence "turn on" and "turn off", respectively. Terbium 12-14 CD2 molecule Homo sapiens 61-64 32971238-4 2020 FPR1 expression on M1/M2a, FPR2 expression on M1, and FPR3 expression of M1 were all decreased in active TB versus LTBI group, while FPR1 over FPR2 expression ratio on NK T cell was increased in active TB versus either NIHS or LTBI group. Terbium 105-107 formyl peptide receptor 1 Homo sapiens 0-4 32971238-4 2020 FPR1 expression on M1/M2a, FPR2 expression on M1, and FPR3 expression of M1 were all decreased in active TB versus LTBI group, while FPR1 over FPR2 expression ratio on NK T cell was increased in active TB versus either NIHS or LTBI group. Terbium 105-107 formyl peptide receptor 3 Homo sapiens 54-58 33296342-1 2020 INTRODUCTION: The interferon-gamma release assays as potent adjunct tools for the quick detection of TB in high burden countries is feasible. Terbium 101-103 interferon gamma Homo sapiens 18-34 32501573-0 2020 Ultrabright terbium nanoparticles for FRET biosensing and in-situ imaging of epidermal growth factor receptors. Terbium 12-19 epidermal growth factor receptor Homo sapiens 77-110 33029834-9 2020 Moreover, the pronounced temperature dependence of the anisotropy that follows from its Tc of 450 K, together with a thermal conductivity of 20 W m-1 K-1 , make Rh2 CoSb a candidate for the development of heat-assisted writing with a recording density in excess of 10 Tb in.-2 . Terbium 268-270 Rh associated glycoprotein Homo sapiens 161-164 33160379-8 2020 CASE PRESENTATION: In two representative cases of conventional advanced CRC, we immunohistochemically examined S100A10 and ANX A2 expressions in which both TB and PDC were prominent. Terbium 156-158 S100 calcium binding protein A10 Homo sapiens 111-118 33160379-8 2020 CASE PRESENTATION: In two representative cases of conventional advanced CRC, we immunohistochemically examined S100A10 and ANX A2 expressions in which both TB and PDC were prominent. Terbium 156-158 annexin A2 Homo sapiens 123-129 33160379-14 2020 CONCLUSIONS: During oncogenesis, membranous S100A10 has the potential to be related to TB of CRC. Terbium 87-89 S100 calcium binding protein A10 Homo sapiens 44-51 31900473-8 2020 IPT reduced the risk of TB by approximately 30% (aHR 0.71 [95%CI 0.63 - 0.81]; absolute risk-difference 1518/100000 women). Terbium 24-26 aryl hydrocarbon receptor Homo sapiens 49-52 31900473-10 2020 CONCLUSIONS: This analysis of programmatic data is reassuring regarding the safety of antenatal IPT, with the greatest benefits against TB disease observed in women with CD4 count<=350cells/mul. Terbium 136-138 CD4 molecule Homo sapiens 170-173 33147218-12 2020 Age (18-29 years), HIV positive and previous TB treatment history were significantly associated with high MTB (p < 0.001), whereas gender (being female) was associated with low MTB (p < 0.001). Terbium 45-47 metallothionein 1J, pseudogene Homo sapiens 106-109 33073797-2 2020 Replacement of a proportion of the cerium chloride in synthesis by a second lanthanide chloride yields a set of materials Ce1-xLnx(OH)2Cl for Ln = La, Pr, Gd, Tb. Terbium 159-161 carboxylesterase 1 Homo sapiens 122-125 32677119-1 2020 A novel folic acid functionalized terbium-doped dendritic fibrous nanoparticle (Tb@KCC-1-NH2 -FA) with high surface area was synthesized using a novel hydrothermal protocol. Terbium 80-82 solute carrier family 12 member 4 Homo sapiens 83-88 32700645-6 2020 The pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were separately as 87%, 98%, 34.78, 0.14, 256.41 and 0.98, indicating a very powerful differentiating ability of IL-2 for LTBI from non-TB controls.For differentiating ATB from LTBI, the pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were 83%, 76%, 3.41, 0.22, 15.47 and 0.87, respectively, suggesting a good differentiating ability of IL-2.Conclusions: These findings showed that IL-2 is a powerful marker for differentiating LTBI from non-TB controls and a good marker for differentiating ATB from LTBI individuals. Terbium 190-192 interleukin 2 Homo sapiens 180-184 32700645-6 2020 The pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were separately as 87%, 98%, 34.78, 0.14, 256.41 and 0.98, indicating a very powerful differentiating ability of IL-2 for LTBI from non-TB controls.For differentiating ATB from LTBI, the pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were 83%, 76%, 3.41, 0.22, 15.47 and 0.87, respectively, suggesting a good differentiating ability of IL-2.Conclusions: These findings showed that IL-2 is a powerful marker for differentiating LTBI from non-TB controls and a good marker for differentiating ATB from LTBI individuals. Terbium 190-192 interleukin 2 Homo sapiens 180-184 32700645-6 2020 The pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were separately as 87%, 98%, 34.78, 0.14, 256.41 and 0.98, indicating a very powerful differentiating ability of IL-2 for LTBI from non-TB controls.For differentiating ATB from LTBI, the pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were 83%, 76%, 3.41, 0.22, 15.47 and 0.87, respectively, suggesting a good differentiating ability of IL-2.Conclusions: These findings showed that IL-2 is a powerful marker for differentiating LTBI from non-TB controls and a good marker for differentiating ATB from LTBI individuals. Terbium 190-192 interleukin 2 Homo sapiens 180-184 32700645-6 2020 The pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were separately as 87%, 98%, 34.78, 0.14, 256.41 and 0.98, indicating a very powerful differentiating ability of IL-2 for LTBI from non-TB controls.For differentiating ATB from LTBI, the pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were 83%, 76%, 3.41, 0.22, 15.47 and 0.87, respectively, suggesting a good differentiating ability of IL-2.Conclusions: These findings showed that IL-2 is a powerful marker for differentiating LTBI from non-TB controls and a good marker for differentiating ATB from LTBI individuals. Terbium 190-192 interleukin 2 Homo sapiens 180-184 32700645-6 2020 The pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were separately as 87%, 98%, 34.78, 0.14, 256.41 and 0.98, indicating a very powerful differentiating ability of IL-2 for LTBI from non-TB controls.For differentiating ATB from LTBI, the pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were 83%, 76%, 3.41, 0.22, 15.47 and 0.87, respectively, suggesting a good differentiating ability of IL-2.Conclusions: These findings showed that IL-2 is a powerful marker for differentiating LTBI from non-TB controls and a good marker for differentiating ATB from LTBI individuals. Terbium 203-205 interleukin 2 Homo sapiens 180-184 32700645-6 2020 The pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were separately as 87%, 98%, 34.78, 0.14, 256.41 and 0.98, indicating a very powerful differentiating ability of IL-2 for LTBI from non-TB controls.For differentiating ATB from LTBI, the pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were 83%, 76%, 3.41, 0.22, 15.47 and 0.87, respectively, suggesting a good differentiating ability of IL-2.Conclusions: These findings showed that IL-2 is a powerful marker for differentiating LTBI from non-TB controls and a good marker for differentiating ATB from LTBI individuals. Terbium 203-205 interleukin 2 Homo sapiens 180-184 32700645-6 2020 The pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were separately as 87%, 98%, 34.78, 0.14, 256.41 and 0.98, indicating a very powerful differentiating ability of IL-2 for LTBI from non-TB controls.For differentiating ATB from LTBI, the pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were 83%, 76%, 3.41, 0.22, 15.47 and 0.87, respectively, suggesting a good differentiating ability of IL-2.Conclusions: These findings showed that IL-2 is a powerful marker for differentiating LTBI from non-TB controls and a good marker for differentiating ATB from LTBI individuals. Terbium 203-205 interleukin 2 Homo sapiens 180-184 32700645-6 2020 The pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were separately as 87%, 98%, 34.78, 0.14, 256.41 and 0.98, indicating a very powerful differentiating ability of IL-2 for LTBI from non-TB controls.For differentiating ATB from LTBI, the pooled sensitivity, specificity, PLR, NLR,DOR and AUROCof IL-2 were 83%, 76%, 3.41, 0.22, 15.47 and 0.87, respectively, suggesting a good differentiating ability of IL-2.Conclusions: These findings showed that IL-2 is a powerful marker for differentiating LTBI from non-TB controls and a good marker for differentiating ATB from LTBI individuals. Terbium 203-205 interleukin 2 Homo sapiens 180-184 32677119-2 2020 In the present work, we report the fluorescent Tb-doted nanomaterial with emission wavelength at 497 nm which confirms the formation of Tb@KCC-1-NH2 -FA. Terbium 47-49 solute carrier family 12 member 4 Homo sapiens 139-144 32677119-2 2020 In the present work, we report the fluorescent Tb-doted nanomaterial with emission wavelength at 497 nm which confirms the formation of Tb@KCC-1-NH2 -FA. Terbium 136-138 solute carrier family 12 member 4 Homo sapiens 139-144 32677119-4 2020 Specially, our desired nanomaterial which has FA moieties on the surface of Tb@KCC-1-NH2-FA where interact with folate receptor (FR) which there is on the surface of the various cancer cells. Terbium 76-78 solute carrier family 12 member 4 Homo sapiens 79-84 32677119-7 2020 The cytotoxicity survey of Tb@KCC-1-NH2 -FA was examined by MTT assays against MDA breast cancer, HT 29 colon cancer and HEK 293 Normal cell lines which confirmed their biocompatible nature with any significant cytotoxic effects even for concentration higher than 900 mug/mL which could be used as a non-toxic catalyst or carrier in biological ambient. Terbium 27-29 solute carrier family 12 member 4 Homo sapiens 30-35 32677119-8 2020 Hence, Tb@KCC-1-NH2 -FA were synthesized using green and hydrothermal method; the process was simple with good productivity and desired nanocomposite was non-toxic. Terbium 7-9 solute carrier family 12 member 4 Homo sapiens 10-15 33162940-8 2020 Both PTH and ABL prevented the immobilization-induced decrease in aBMD, metaphyseal and epiphyseal Tb.Th, and metaphyseal Tb.N. Terbium 99-101 parathyroid hormone Rattus norvegicus 5-8 32844824-6 2020 As a proof-of-concept, a 10-fold increase in the DESI-MS response for insulin was achieved following the TB-IEF preconcentration, whilst simultaneously isolating the target solutes from their sample matrix. Terbium 105-107 insulin Homo sapiens 70-77 32829068-4 2020 LGR5 expression was evaluated by RNAscope, a newly developed RNA in situ hybridization technique, using a tissue microarray consisting of 55 patient samples of TB in colon adenocarcinoma (CA) selected from the medical archives at our hospital. Terbium 160-162 leucine rich repeat containing G protein-coupled receptor 5 Homo sapiens 0-4 32951482-0 2021 TB Free India by 2025: Hype or Hope. Terbium 0-2 FIC domain protein adenylyltransferase Homo sapiens 23-27 32505775-0 2020 Higher T-SPOT.TB Threshold May Aid in Diagnosing Active Tuberculosis? Terbium 14-16 activation induced cytidine deaminase Homo sapiens 31-34 32505775-2 2020 BACKGROUND: This study aimed to determine whether increased cut-off of the T-SPOT.TB could aid in diagnosing active tuberculosis (ATB). Terbium 82-84 activation induced cytidine deaminase Homo sapiens 91-94 32866942-1 2020 OBJECTIVE: QFT-Plus"s newly added antigen elicited a specific CD8 T-cell response, which is closely related to active TB (ATB), and the IGRA based on Heparin-binding haemagglutinin (HBHA-IGRA) is a promising tool in latent tuberculosis infection (LTBI) diagnosis. Terbium 118-120 CD8a molecule Homo sapiens 62-65 32805836-0 2020 The Stimulus Response of GQDs Sensitized Tb/GMP ICP Nanoparticles with Dual-Responsive Ratiometric Fluorescence: Towards Point-of-Use Analysis of Acetylcholinesterase and Organophosphorus Pesticides Poisoning with Acetylcholinesterase as a Biomarker. Terbium 41-43 acetylcholinesterase (Cartwright blood group) Homo sapiens 146-166 32805836-0 2020 The Stimulus Response of GQDs Sensitized Tb/GMP ICP Nanoparticles with Dual-Responsive Ratiometric Fluorescence: Towards Point-of-Use Analysis of Acetylcholinesterase and Organophosphorus Pesticides Poisoning with Acetylcholinesterase as a Biomarker. Terbium 41-43 acetylcholinesterase (Cartwright blood group) Homo sapiens 214-234 32805836-1 2020 In this study, by rationally designing the stimulus response of graphene quantum dots (GQDs) sensitized Tb/GMP infinite coordination polymer (ICP) nanoparticles, we have constructed a smartphone-based colorimetric assay with ratiometric fluorescence, which could be applied for the detection of acetylcholinesterase (AChE) and organophosphorus pesticides (OPs) directly. Terbium 104-106 acetylcholinesterase (Cartwright blood group) Homo sapiens 295-315 32805836-1 2020 In this study, by rationally designing the stimulus response of graphene quantum dots (GQDs) sensitized Tb/GMP infinite coordination polymer (ICP) nanoparticles, we have constructed a smartphone-based colorimetric assay with ratiometric fluorescence, which could be applied for the detection of acetylcholinesterase (AChE) and organophosphorus pesticides (OPs) directly. Terbium 104-106 acetylcholinesterase (Cartwright blood group) Homo sapiens 317-321 32805836-4 2020 With the presence of thiocholine (TCh), an enzymatic product hydrolyzed from acetylthiocholine (ATCh) by AChE, the competitive coordination of Tb3+ between GMP and TCh results in the collapse of ICP network and thereby the release of GQDs into the solution, thus, the fluorescence of Tb/GMP turns off and the fluorescence of GQDs turns on. Terbium 143-145 acetylcholinesterase (Cartwright blood group) Homo sapiens 105-109 32805836-6 2020 Moreover, when OPs are subsequently introduced, the activity of AChE is blocked, thus preventing the stimulus response of GQDs@Tb/GMP ICP nanoparticles, leading to the fluorescent color change from greenish-blue to green, which could also be employed for OPs detection. Terbium 127-129 acetylcholinesterase (Cartwright blood group) Homo sapiens 64-68 32719030-1 2020 Interferon-gamma (IFN-gamma) release assays (IGRAs) are increasingly used to test for latent TB infection. Terbium 93-95 interferon gamma Homo sapiens 0-16 32719030-1 2020 Interferon-gamma (IFN-gamma) release assays (IGRAs) are increasingly used to test for latent TB infection. Terbium 93-95 interferon gamma Homo sapiens 18-27 32780727-8 2020 Receiver-operating-characteristics analyses using a 5-protein panel (CFHR5, LRG1, CRP, LBP and SAA1) exhibited discriminatory power in distinguishing between TB and ORD (AUC =0.81).ConclusionsWe report the most comprehensive TB plasma proteome to date, identifying numerous novel markers with verification in two independent cohorts, which led to a 5-protein biosignature with potential to improve TB diagnosis. Terbium 158-160 complement factor H related 5 Homo sapiens 69-74 32780727-8 2020 Receiver-operating-characteristics analyses using a 5-protein panel (CFHR5, LRG1, CRP, LBP and SAA1) exhibited discriminatory power in distinguishing between TB and ORD (AUC =0.81).ConclusionsWe report the most comprehensive TB plasma proteome to date, identifying numerous novel markers with verification in two independent cohorts, which led to a 5-protein biosignature with potential to improve TB diagnosis. Terbium 158-160 leucine rich alpha-2-glycoprotein 1 Homo sapiens 76-80 32780727-8 2020 Receiver-operating-characteristics analyses using a 5-protein panel (CFHR5, LRG1, CRP, LBP and SAA1) exhibited discriminatory power in distinguishing between TB and ORD (AUC =0.81).ConclusionsWe report the most comprehensive TB plasma proteome to date, identifying numerous novel markers with verification in two independent cohorts, which led to a 5-protein biosignature with potential to improve TB diagnosis. Terbium 158-160 C-reactive protein Homo sapiens 82-85 32780727-8 2020 Receiver-operating-characteristics analyses using a 5-protein panel (CFHR5, LRG1, CRP, LBP and SAA1) exhibited discriminatory power in distinguishing between TB and ORD (AUC =0.81).ConclusionsWe report the most comprehensive TB plasma proteome to date, identifying numerous novel markers with verification in two independent cohorts, which led to a 5-protein biosignature with potential to improve TB diagnosis. Terbium 158-160 lipopolysaccharide binding protein Homo sapiens 87-90 32780727-8 2020 Receiver-operating-characteristics analyses using a 5-protein panel (CFHR5, LRG1, CRP, LBP and SAA1) exhibited discriminatory power in distinguishing between TB and ORD (AUC =0.81).ConclusionsWe report the most comprehensive TB plasma proteome to date, identifying numerous novel markers with verification in two independent cohorts, which led to a 5-protein biosignature with potential to improve TB diagnosis. Terbium 158-160 serum amyloid A1 Homo sapiens 95-99 32526553-8 2020 Moreover, their anti-TB activity was found to be related to the NDH-2 inhibition. Terbium 21-23 DExH-box helicase 9 Homo sapiens 64-69 32387752-12 2020 CONCLUSIONS: Based on this case-control study, SNPs rs7643645 and rs2276707 in NR1I2 may contribute to susceptibility to ATDH in Eastern Chinese Han anti-TB treatment patients. Terbium 154-156 nuclear receptor subfamily 1 group I member 2 Homo sapiens 79-84 33295721-14 2020 TB was developed in only one patient out of 393 patients who were treated with anti-TNF treatments and the the prevalence of TB development was found 255/100.000. Terbium 0-2 tumor necrosis factor Homo sapiens 84-87 33295721-14 2020 TB was developed in only one patient out of 393 patients who were treated with anti-TNF treatments and the the prevalence of TB development was found 255/100.000. Terbium 125-127 tumor necrosis factor Homo sapiens 84-87 32806745-7 2020 The simultaneous quantification of CEA, NSE, and PSA at different concentrations from the same serum sample demonstrated actual multiplexing Tb-to-QD FRET immunoassays and the potential of this technology for translation into clinical diagnostics. Terbium 141-143 CEA cell adhesion molecule 3 Homo sapiens 35-38 32983107-7 2020 Furthermore, CD15 expression level at diagnosis was associated with TB culture conversion after 2 months of therapy (OR: 0.14, 95% CI: 0.02, 0.89), a standard measure of early TB treatment success. Terbium 68-70 fucosyltransferase 4 Homo sapiens 13-17 32983107-7 2020 Furthermore, CD15 expression level at diagnosis was associated with TB culture conversion after 2 months of therapy (OR: 0.14, 95% CI: 0.02, 0.89), a standard measure of early TB treatment success. Terbium 176-178 fucosyltransferase 4 Homo sapiens 13-17 32320824-10 2020 CONCLUSIONS: The polymorphisms of IL27, rs17855750, but not rs181206 and rs26528, plays a protective role on the susceptibility to TB. Terbium 131-133 interleukin 27 Homo sapiens 34-38 32806745-7 2020 The simultaneous quantification of CEA, NSE, and PSA at different concentrations from the same serum sample demonstrated actual multiplexing Tb-to-QD FRET immunoassays and the potential of this technology for translation into clinical diagnostics. Terbium 141-143 enolase 2 Homo sapiens 40-43 32806745-7 2020 The simultaneous quantification of CEA, NSE, and PSA at different concentrations from the same serum sample demonstrated actual multiplexing Tb-to-QD FRET immunoassays and the potential of this technology for translation into clinical diagnostics. Terbium 141-143 kallikrein related peptidase 3 Homo sapiens 49-52 32192926-3 2020 The present study compared the surgical outcomes of TB and ES for harvesting the anterolateral thigh free flap (ALTFF). Terbium 52-54 arachidonate 5-lipoxygenase activating protein Homo sapiens 106-110 32418903-5 2020 Mucus-penetrating-microparticles(NAC/PLGA-MPP) were developed combining the benefits of anti-TB drug with host defence peptides(HDP). Terbium 93-95 NLR family, pyrin domain containing 1A Mus musculus 33-36 32418903-11 2020 The inhalation of NAC/PLGA-MPP encapsulated with IDR-1018 significantly reduced (p < .05) bacterial load (up to ~3.02LogCFU/ml) and inflammation in lungs in a mouse model of TB compared to untreated and blank treated animals in 6 weeks of daily dose. Terbium 174-176 NLR family, pyrin domain containing 1A Mus musculus 18-21 32756559-15 2020 The findings have facilitated a policy decision by National TB Programme mandating the use of Xpert MTB/RIF as a primary diagnostic tool for TB diagnosis in children, which is being scaled-up. Terbium 60-62 ras homolog family member F, filopodia associated Homo sapiens 104-107 32672500-0 2021 Experimental and computational interaction studies of terbium (III) and lanthanide (III) complexes containing 2,2"-bipyridine with bovine serum albumin and their in vitro anticancer and antimicrobial activities. Terbium 54-61 albumin Homo sapiens 138-151 31980958-9 2020 Absence of TB was associated with low ZEB2 expression (p = 0.003). Terbium 11-13 zinc finger E-box binding homeobox 2 Homo sapiens 38-42 32720695-8 2021 The loss of QGIT positivity during pregnancy was explained by decreased IFNgamma production in response to TB antigen and/or mitogen. Terbium 107-109 interferon gamma Homo sapiens 72-80 32639724-7 2020 Global analysis of the luminescence titration experiment points to the formation of 4:1, 3:1, and 3:2 [TbL1]/Eu heteropolynuclear assemblies, exhibiting a strong preference to forming [TbL1]3Eu2 at increased europium concentrations, with energy transfer occurring between the kinetically inert terbium complex and added europium cations. Terbium 294-301 transducin beta like 1 Y-linked Homo sapiens 103-107 32639724-7 2020 Global analysis of the luminescence titration experiment points to the formation of 4:1, 3:1, and 3:2 [TbL1]/Eu heteropolynuclear assemblies, exhibiting a strong preference to forming [TbL1]3Eu2 at increased europium concentrations, with energy transfer occurring between the kinetically inert terbium complex and added europium cations. Terbium 294-301 transducin beta like 1 Y-linked Homo sapiens 185-189 32736608-4 2020 The pre-ART CD4 count lower than 50 cells/mm3 was found to be significantly associated with development of TB-IRIS. Terbium 107-109 CD4 molecule Homo sapiens 12-15 32736608-5 2020 Similarly, patients with higher than 4-fold increase in CD4 cell count after antiretroviral therapy (ART) had significantly higher odds of having TB-IRIS. Terbium 146-148 CD4 molecule Homo sapiens 56-59 32736608-9 2020 Lower baseline CD4 count and rapid increase in CD4 count are the major risk factors associated with the occurrence of paradoxical TB-IRIS. Terbium 130-132 CD4 molecule Homo sapiens 15-18 32736608-9 2020 Lower baseline CD4 count and rapid increase in CD4 count are the major risk factors associated with the occurrence of paradoxical TB-IRIS. Terbium 130-132 CD4 molecule Homo sapiens 47-50 32722132-5 2020 The construct was additionally doped with Tb and Eu during the CaF2 core synthesis to prepare nanoparticles (NPs) with X-ray luminescent properties for potential application in fluorescence imaging. Terbium 42-44 CCR4-NOT transcription complex subunit 8 Homo sapiens 63-67 32718398-7 2020 The strong linear association between CAD4TB score and Xpert positivity was found in both community and hospital settings.CONCLUSION: The strong association between CAD4TB scores and Xpert positivity provide evidence that an ACR-based pre-screening performs well when implemented at scale in a high-burden setting. Terbium 169-171 cadherin 4 Homo sapiens 38-42 32573632-3 2020 Here, we present the development and application of a homogeneous methyltransferase (SET7/9) assay based on time-gated Forster resonance energy transfer (TG-FRET) between terbium complexes (Tb) and luminescent semiconductor quantum dots (QDs). Terbium 190-192 SET domain containing 7, histone lysine methyltransferase Homo sapiens 85-91 32573632-4 2020 Specific binding of a Tb-antibody conjugate to a SET7/9-methylated Lys4 on a histone H3(1-21) peptide substrate attached to the QD surface resulted in efficient FRET and provided the mechanism for monitoring the SET7/9 activity. Terbium 22-24 SET domain containing 7, histone lysine methyltransferase Homo sapiens 49-55 32573632-4 2020 Specific binding of a Tb-antibody conjugate to a SET7/9-methylated Lys4 on a histone H3(1-21) peptide substrate attached to the QD surface resulted in efficient FRET and provided the mechanism for monitoring the SET7/9 activity. Terbium 22-24 SET domain containing 7, histone lysine methyltransferase Homo sapiens 212-218 32339714-2 2020 METHODS: We evaluated the IFN-gamma responses (QuantiFERON-TB Gold-In-Tube (QFT-GIT) TSPOT-TB) stratified according to the M.tb spoligotype of the culture isolate obtained from the same patients with confirmed active TB (n = 91). Terbium 59-61 interferon gamma Homo sapiens 26-35 32339714-4 2020 RESULTS: In HIV uninfected patients TSPOT.TB and QFT-GIT IFN-gamma responses were 5-fold (p < 0.01) and 2-fold higher (p < 0.05) for those infected with family 33 compared to the LAM strain (additionally, TSPOT.TB responses were 5.6-fold (p < 0.05) and 2.6-fold higher (p < 0.05) for the patients infected with the family 33 versus the X strain and Beijing versus the LAM strain, respectively). Terbium 211-213 interferon gamma Homo sapiens 57-66 32584968-3 2021 METHODS: We used a model of TB transmission to estimate the numbers of individuals who could be tested by interferon-gamma release assay (IGRA) and treated for LTBI with three months of self-administered rifapentine and isoniazid (3HP) under various TTT scenarios. Terbium 28-30 interferon gamma Homo sapiens 106-122 32626768-1 2020 One of the well-studied phase II drug metabolizing enzymes is N-acetyltransferase 2 (NAT2) which has an essential role in the detoxification and metabolism of several environmental toxicants and many therapeutic drugs like isoniazid (antituberculosis, TB) and antimicrobial sulfonamides. Terbium 252-254 N-acetyltransferase 2 Homo sapiens 62-83 32574211-10 2020 These findings support a search for selective activators of TFEB for HDT of TB. Terbium 76-78 transcription factor EB Mus musculus 60-64 32626768-1 2020 One of the well-studied phase II drug metabolizing enzymes is N-acetyltransferase 2 (NAT2) which has an essential role in the detoxification and metabolism of several environmental toxicants and many therapeutic drugs like isoniazid (antituberculosis, TB) and antimicrobial sulfonamides. Terbium 252-254 N-acetyltransferase 2 Homo sapiens 85-89 32603174-4 2020 The curious in-plane spin-momentum locking is remarkably robust and remains intact across a paramagnetic-antiferromagnetic transition in spite of spin-orbit interaction on Rh atoms being considerably weaker than the out-of-plane exchange field due to the Tb 4f moments. Terbium 255-257 spindlin 1 Homo sapiens 21-25 32125282-5 2020 By MSRE-qPCR, multiple genes of the IL-12-IFN-gamma signaling pathway (IL12B, IL12RB2, TYK2, IFNGR1, JAK1 and JAK2) were hyper-methylated in TB patients. Terbium 141-143 Janus kinase 2 Homo sapiens 110-114 33163022-9 2020 Patients with CD4 <= 349 were almost twice as likely to have TB, than those with CD4 >=500. Terbium 61-63 CD4 molecule Homo sapiens 14-17 32125282-5 2020 By MSRE-qPCR, multiple genes of the IL-12-IFN-gamma signaling pathway (IL12B, IL12RB2, TYK2, IFNGR1, JAK1 and JAK2) were hyper-methylated in TB patients. Terbium 141-143 Janus kinase 1 Homo sapiens 101-105 32134742-3 2020 Using the well-established mouse model of TB, our new data provides evidence that the alarmin S100A8/A9 mediates neutrophil accumulation during progression to chronic TB. Terbium 42-44 S100 calcium binding protein A8 (calgranulin A) Mus musculus 94-100 32134742-3 2020 Using the well-established mouse model of TB, our new data provides evidence that the alarmin S100A8/A9 mediates neutrophil accumulation during progression to chronic TB. Terbium 167-169 S100 calcium binding protein A8 (calgranulin A) Mus musculus 94-100 32134742-6 2020 These findings are further substantiated by increased expression of S100A8 and S100A9 mRNA in whole blood in human TB progressors when compared to non-progressors, and rapidly decreased S100A8/A9 protein levels in the serum upon TB treatment. Terbium 115-117 S100 calcium binding protein A8 Homo sapiens 68-74 32134742-6 2020 These findings are further substantiated by increased expression of S100A8 and S100A9 mRNA in whole blood in human TB progressors when compared to non-progressors, and rapidly decreased S100A8/A9 protein levels in the serum upon TB treatment. Terbium 115-117 S100 calcium binding protein A9 Homo sapiens 79-85 32134742-6 2020 These findings are further substantiated by increased expression of S100A8 and S100A9 mRNA in whole blood in human TB progressors when compared to non-progressors, and rapidly decreased S100A8/A9 protein levels in the serum upon TB treatment. Terbium 229-231 S100 calcium binding protein A8 Homo sapiens 186-192 32134742-8 2020 Thus, our results support targeting S100A8/A9 pathways as host-directed therapy for TB. Terbium 84-86 S100 calcium binding protein A8 (calgranulin A) Mus musculus 36-42 32440172-3 2020 Here, we report a rare case of TB in Guizhou Province of China that was identified as RIF-susceptible by the Xpert MTB/RIF assay, but later was confirmed as MDR-TB by DST, and its successful treatment with effective second-line anti-TB drugs. Terbium 31-33 ras homolog family member F, filopodia associated Homo sapiens 86-89 32456524-6 2020 Co-culture cells challenged with gamma-irradiated M.Tb under various conditions resulted in high interleukin (IL)-10 secretion and high percentage of PD1 expression on CD8 T cells, which might be due to defective antigen presentation of TAP on dendritic cells and macrophages. Terbium 52-54 IL10 Sus scrofa 97-116 32456524-6 2020 Co-culture cells challenged with gamma-irradiated M.Tb under various conditions resulted in high interleukin (IL)-10 secretion and high percentage of PD1 expression on CD8 T cells, which might be due to defective antigen presentation of TAP on dendritic cells and macrophages. Terbium 52-54 MHC class I antigen 1 Sus scrofa 150-153 32456524-6 2020 Co-culture cells challenged with gamma-irradiated M.Tb under various conditions resulted in high interleukin (IL)-10 secretion and high percentage of PD1 expression on CD8 T cells, which might be due to defective antigen presentation of TAP on dendritic cells and macrophages. Terbium 52-54 putative ABC-transporter Sus scrofa 237-240 32408647-1 2020 The reaction of the Schiff base ligand o-OH-C6H4-CH=N-C(CH2OH)3, H4L, with Ni(O2CMe)2 4H2O and lanthanide nitrate salts in a 4 : 2 : 1 ratio lead to the formation of the trinuclear complexes [Ni2Ln(H3L)4(O2CMe)2](NO3) (Ln = Sm (1), Eu (2), Gd (3), Tb (4)). Terbium 248-250 H4 clustered histone 7 Homo sapiens 65-68 32125282-4 2020 Here, we evaluated the DNA methylation status of TB patients and their asymptomatic household contacts demonstrating that TB patients have DNA hyper-methylation of the IL-2-STAT5, TNF-NF-kappaB and IFN-gamma signaling pathways. Terbium 49-51 interleukin 2 Homo sapiens 168-172 32125282-4 2020 Here, we evaluated the DNA methylation status of TB patients and their asymptomatic household contacts demonstrating that TB patients have DNA hyper-methylation of the IL-2-STAT5, TNF-NF-kappaB and IFN-gamma signaling pathways. Terbium 49-51 signal transducer and activator of transcription 5A Homo sapiens 173-178 32125282-4 2020 Here, we evaluated the DNA methylation status of TB patients and their asymptomatic household contacts demonstrating that TB patients have DNA hyper-methylation of the IL-2-STAT5, TNF-NF-kappaB and IFN-gamma signaling pathways. Terbium 49-51 tumor necrosis factor Homo sapiens 180-183 32125282-4 2020 Here, we evaluated the DNA methylation status of TB patients and their asymptomatic household contacts demonstrating that TB patients have DNA hyper-methylation of the IL-2-STAT5, TNF-NF-kappaB and IFN-gamma signaling pathways. Terbium 49-51 interferon gamma Homo sapiens 198-207 32125282-4 2020 Here, we evaluated the DNA methylation status of TB patients and their asymptomatic household contacts demonstrating that TB patients have DNA hyper-methylation of the IL-2-STAT5, TNF-NF-kappaB and IFN-gamma signaling pathways. Terbium 122-124 interleukin 2 Homo sapiens 168-172 32125282-4 2020 Here, we evaluated the DNA methylation status of TB patients and their asymptomatic household contacts demonstrating that TB patients have DNA hyper-methylation of the IL-2-STAT5, TNF-NF-kappaB and IFN-gamma signaling pathways. Terbium 122-124 signal transducer and activator of transcription 5A Homo sapiens 173-178 32125282-4 2020 Here, we evaluated the DNA methylation status of TB patients and their asymptomatic household contacts demonstrating that TB patients have DNA hyper-methylation of the IL-2-STAT5, TNF-NF-kappaB and IFN-gamma signaling pathways. Terbium 122-124 tumor necrosis factor Homo sapiens 180-183 32125282-4 2020 Here, we evaluated the DNA methylation status of TB patients and their asymptomatic household contacts demonstrating that TB patients have DNA hyper-methylation of the IL-2-STAT5, TNF-NF-kappaB and IFN-gamma signaling pathways. Terbium 122-124 interferon gamma Homo sapiens 198-207 32125282-5 2020 By MSRE-qPCR, multiple genes of the IL-12-IFN-gamma signaling pathway (IL12B, IL12RB2, TYK2, IFNGR1, JAK1 and JAK2) were hyper-methylated in TB patients. Terbium 141-143 interleukin 12B Homo sapiens 71-76 32125282-5 2020 By MSRE-qPCR, multiple genes of the IL-12-IFN-gamma signaling pathway (IL12B, IL12RB2, TYK2, IFNGR1, JAK1 and JAK2) were hyper-methylated in TB patients. Terbium 141-143 interleukin 12 receptor subunit beta 2 Homo sapiens 78-85 32125282-5 2020 By MSRE-qPCR, multiple genes of the IL-12-IFN-gamma signaling pathway (IL12B, IL12RB2, TYK2, IFNGR1, JAK1 and JAK2) were hyper-methylated in TB patients. Terbium 141-143 tyrosine kinase 2 Homo sapiens 87-91 32125282-5 2020 By MSRE-qPCR, multiple genes of the IL-12-IFN-gamma signaling pathway (IL12B, IL12RB2, TYK2, IFNGR1, JAK1 and JAK2) were hyper-methylated in TB patients. Terbium 141-143 interferon gamma receptor 1 Homo sapiens 93-99 32432943-6 2021 The interaction of SCAP and SQSTM1 requires the WD40 domain of SCAP and the TB domain of SQSTM1. Terbium 76-78 SREBF chaperone Mus musculus 19-23 32432943-6 2021 The interaction of SCAP and SQSTM1 requires the WD40 domain of SCAP and the TB domain of SQSTM1. Terbium 76-78 sequestosome 1 Mus musculus 28-34 32432943-6 2021 The interaction of SCAP and SQSTM1 requires the WD40 domain of SCAP and the TB domain of SQSTM1. Terbium 76-78 sequestosome 1 Mus musculus 89-95 32477361-6 2020 Since IL-1 may contribute to LZD toxicity and does influence TB pathology, we targeted this pathway with a potential host-directed therapy (HDT). Terbium 61-63 interleukin 1 alpha Homo sapiens 6-10 32477361-7 2020 We hypothesized LZD efficacy could be enhanced by modulation of IL-1 pathway to reduce bone marrow toxicity and TB associated-inflammation. Terbium 112-114 interleukin 1 alpha Homo sapiens 64-68 32477361-14 2020 Together, our data support that inhibition of IL-1 in combination with LZD has potential to be an effective HDT for TB and the need for further research in this area. Terbium 116-118 interleukin 1 alpha Homo sapiens 46-50 32398634-6 2022 In the TB, mean muscle activity values were significantly (p < 0.001) greater in the stable SwB intervention than the SBp and UBp. Terbium 7-9 selenium binding protein 1 Homo sapiens 118-121 32398634-6 2022 In the TB, mean muscle activity values were significantly (p < 0.001) greater in the stable SwB intervention than the SBp and UBp. Terbium 7-9 ubiquitin specific peptidase 1 Homo sapiens 126-129 32474547-6 2020 However, among the XDR-TB isolates (n = 4), one specimen (25%) was found to be associated with a mutation in atpE gene at position 49, resulting in the amino acid leucine replaced by proline (L-49-P). Terbium 23-25 ATP synthase F1 subunit epsilon Homo sapiens 109-113 32149887-9 2020 Individual analysis of TB heads showed significantly greater CSA increases in the lateral head for MJ, MJ + SJ, and SJ + MJ compared with SJ. Terbium 23-25 ERCC excision repair 8, CSA ubiquitin ligase complex subunit Homo sapiens 61-64 32501260-2 2020 We assessed associations between diabetes and interferon-gamma (IFN-gamma) TB antigen response among adults with TB infection using US representative data. Terbium 75-77 interferon gamma Homo sapiens 46-62 32501260-2 2020 We assessed associations between diabetes and interferon-gamma (IFN-gamma) TB antigen response among adults with TB infection using US representative data. Terbium 75-77 interferon gamma Homo sapiens 64-73 31900748-11 2020 CONCLUSION: The incidence of TB in patients with rheumatic diseases exposed TNF inhibitor considering all countries was 9.62 cases per 1000 patients exposed. Terbium 29-31 tumor necrosis factor Homo sapiens 76-79 32007302-4 2020 The homozygosity for SFTPA2 +26 C > A SNP variant allele occurred less commonly within TB, while homozygosity for the FCN1 -542 G > A major allele was less frequent within the control group. Terbium 87-89 surfactant protein A2 Homo sapiens 21-27 32260161-1 2020 A detailed comparison of the gas permeability of four Polymers of Intrinsic Microporosity containing Troger"s base (TB-PIMs) is reported. Terbium 116-118 gastrin Homo sapiens 29-32 32225094-3 2020 TB has a larger particle size, a lower surface area, and lower level of particle aggregation, while being the most eco-friendly grade among the CB family. Terbium 0-2 ciliogenesis associated kinase 1 Homo sapiens 115-118 31926897-1 2020 Antagonists of the transient receptor potential vanilloid-1 (TRPV1) channel alter body temperature (Tb) in laboratory animals and humans: most cause hyperthermia; some produce hypothermia; and yet others have no effect. Terbium 100-102 transient receptor potential cation channel subfamily V member 1 Homo sapiens 19-59 31926897-1 2020 Antagonists of the transient receptor potential vanilloid-1 (TRPV1) channel alter body temperature (Tb) in laboratory animals and humans: most cause hyperthermia; some produce hypothermia; and yet others have no effect. Terbium 100-102 transient receptor potential cation channel subfamily V member 1 Homo sapiens 61-66 31926897-7 2020 A Tb response occurs when a TRPV1 antagonist blocks (in case of hyperthermia) or potentiates (hypothermia) the tonic TRPV1 activation by protons somewhere in the trunk, perhaps in muscles, and - via the acido-antithermogenic and acido-antivasoconstrictor reflexes - modulates thermogenesis and skin vasoconstriction. Terbium 2-4 transient receptor potential cation channel subfamily V member 1 Homo sapiens 28-33 31926897-7 2020 A Tb response occurs when a TRPV1 antagonist blocks (in case of hyperthermia) or potentiates (hypothermia) the tonic TRPV1 activation by protons somewhere in the trunk, perhaps in muscles, and - via the acido-antithermogenic and acido-antivasoconstrictor reflexes - modulates thermogenesis and skin vasoconstriction. Terbium 2-4 transient receptor potential cation channel subfamily V member 1 Homo sapiens 117-122 31926897-8 2020 In this work, we used a mathematical model to analyze Tb data from human clinical trials of TRPV1 antagonists. Terbium 54-56 transient receptor potential cation channel subfamily V member 1 Homo sapiens 92-97 31926897-12 2020 We also conducted a meta-analysis of Tb data from human trials and found that polymodal TRPV1 antagonists (ABT-102, AZD1386, and V116517) increase Tb, whereas the mode-selective blocker NEO6860 does not. Terbium 147-149 transient receptor potential cation channel subfamily V member 1 Homo sapiens 88-93 32225094-13 2020 TB proved to be an outstanding eco-filler for compounds to be used in injection molding and 3D printing technologies. Terbium 0-2 ciliogenesis associated kinase 1 Homo sapiens 31-34 32192622-9 2020 Patients that attended the clinics by foot (ARR 3.38) (P < 0.05), females (ARR: 1.25) and HIV negative patients (ARR: 1.20) were more likely to achieve TB cure. Terbium 152-154 arrestin 3 Homo sapiens 44-49 32265833-6 2020 In turn, TB+DM showed even higher levels of interferon gamma -IFN-gamma- and hGH (vs. TB), or IL-6, C reactive protein, cortisol and hGH (vs. DM). Terbium 9-11 interleukin 6 Homo sapiens 94-98 32265833-6 2020 In turn, TB+DM showed even higher levels of interferon gamma -IFN-gamma- and hGH (vs. TB), or IL-6, C reactive protein, cortisol and hGH (vs. DM). Terbium 9-11 C-reactive protein Homo sapiens 100-118 32265833-9 2020 Leptin was also decreased in both TB cases, particularly in the TB group, revealing a lower body mass index, as well. Terbium 34-36 leptin Homo sapiens 0-6 32265833-9 2020 Leptin was also decreased in both TB cases, particularly in the TB group, revealing a lower body mass index, as well. Terbium 64-66 leptin Homo sapiens 0-6 31727517-1 2020 In this work, a label-free, selective, and sensitive luminescent sensing platform was established for tyrosinase (TYR) activity monitoring and its inhibitor screening using one kind of lanthanide coordination polymer nanoparticles AMP-Tb/Ag+. Terbium 235-237 tyrosinase Homo sapiens 102-112 31727517-1 2020 In this work, a label-free, selective, and sensitive luminescent sensing platform was established for tyrosinase (TYR) activity monitoring and its inhibitor screening using one kind of lanthanide coordination polymer nanoparticles AMP-Tb/Ag+. Terbium 235-237 tyrosinase Homo sapiens 114-117 32065177-2 2020 Herein we report an easy approach to the preparation of a heat-set lanthanide-based metallogel (H6L/Tb gel) with stable luminescence from 5,5",5""-(1,3,5-triazine-2,4,6-triyl)tris(azanediyl) triisophthalate (H6L) as a Tb3+ coordinating ligand. Terbium 218-221 H6 family homeobox 2 Homo sapiens 96-99 32065177-2 2020 Herein we report an easy approach to the preparation of a heat-set lanthanide-based metallogel (H6L/Tb gel) with stable luminescence from 5,5",5""-(1,3,5-triazine-2,4,6-triyl)tris(azanediyl) triisophthalate (H6L) as a Tb3+ coordinating ligand. Terbium 218-221 H6 family homeobox 2 Homo sapiens 208-211 32233619-8 2020 The Xpert MTB/RIF group had a significantly shorter interval for the initiation of anti-MDR/ RR-TB treatment {1 [1-1] vs. 52 [47-57] days, P<0.0001}; and following two-month chemotherapy, the percentage of positive culture MDR/RR-TB patients in the Xpert MTB/RIF group was significantly reduced (24.18% vs. 50%, P=0.0003). Terbium 11-13 ras homolog family member F, filopodia associated Homo sapiens 259-262 32233619-11 2020 We recommend that re-treatment PTB patients receive anti-RR/TB chemotherapy following a positive RFP resistance result in the Xpert MTB/RIF assay. Terbium 32-34 ras homolog family member F, filopodia associated Homo sapiens 136-139 31884393-1 2020 A novel fluorescent probe for detection of HT 29 cancer cells was developed based on terbium-doped dendritic fibrous nanosilica functionalized by folic acid (Tb@KCC-1-NH2-FA). Terbium 158-160 solute carrier family 12 member 4 Homo sapiens 161-166 31884393-2 2020 Using this probe, fluorescence signals was emitted by Tb@KCC-1-NH2-FA at 490 nm by applying 380 nm as excitation wavelength. Terbium 54-56 solute carrier family 12 member 4 Homo sapiens 57-62 31884393-3 2020 The reported probe is based on the interaction between FA decorated on the surface of Tb@KCC-1-NH2-FA and folate receptor (FR) which is overexpressed on the surface of the most of cancer cells. Terbium 86-88 solute carrier family 12 member 4 Homo sapiens 89-94 31884393-4 2020 Fluorescence microscopy and flow cytometry were utilized to verify the uptake of Tb@KCC-1-NH2-FA with FR-positive HT 29 cancer cells. Terbium 81-83 solute carrier family 12 member 4 Homo sapiens 84-89 31884393-5 2020 The specificity of Tb@KCC-1-NH2-FA towards FR-positive cells was approved by staining HEK 293 cells as FR-negative cells with Tb@KCC-1-NH2-FA which obtained results approved selective differentiation of normal cells with the FA-decorated nanomaterials. Terbium 19-21 solute carrier family 12 member 4 Homo sapiens 22-27 31884393-5 2020 The specificity of Tb@KCC-1-NH2-FA towards FR-positive cells was approved by staining HEK 293 cells as FR-negative cells with Tb@KCC-1-NH2-FA which obtained results approved selective differentiation of normal cells with the FA-decorated nanomaterials. Terbium 19-21 solute carrier family 12 member 4 Homo sapiens 129-134 31884393-5 2020 The specificity of Tb@KCC-1-NH2-FA towards FR-positive cells was approved by staining HEK 293 cells as FR-negative cells with Tb@KCC-1-NH2-FA which obtained results approved selective differentiation of normal cells with the FA-decorated nanomaterials. Terbium 126-128 solute carrier family 12 member 4 Homo sapiens 22-27 31884393-5 2020 The specificity of Tb@KCC-1-NH2-FA towards FR-positive cells was approved by staining HEK 293 cells as FR-negative cells with Tb@KCC-1-NH2-FA which obtained results approved selective differentiation of normal cells with the FA-decorated nanomaterials. Terbium 126-128 solute carrier family 12 member 4 Homo sapiens 129-134 31884393-6 2020 The cytotoxicity of Tb@KCC-1-NH2-FA was evaluated by MTT assay which confirmed their biocompatible nature. Terbium 20-22 solute carrier family 12 member 4 Homo sapiens 23-28 31884393-8 2020 Due to the room temperature stability of Tb@KCC-1-NH2-FA, this cytosensor could be developed in a simple way with exceptional specificity which may show potential applications for early stage detection of colon cancer. Terbium 41-43 solute carrier family 12 member 4 Homo sapiens 44-49 32011125-0 2020 Unusually Distorted Pseudo-Octahedral Coordination Environment Around CoII from Thioether Schiff Base Ligands in Dinuclear [CoLn] (Ln = La, Gd, Tb, Dy, Ho) Complexes: Synthesis, Structure, and Understanding of Magnetic Behavior. Terbium 144-146 mitochondrially encoded cytochrome c oxidase II Homo sapiens 70-74 32011125-1 2020 The synthesis, structural characterization, and magnetic behavior of a new family of binuclear CoII-LnIII complexes of formula [LnIIICoIIL2(NO3)3] H2O (Ln = La, 1; Gd, 2; Tb, 3; Dy, 4; Ho, 5; HL = 3-methoxy-N-(2-(methylsulfanyl)phenyl)salicylaldimine) have been reported. Terbium 171-173 mitochondrially encoded cytochrome c oxidase II Homo sapiens 95-99 31967118-1 2020 The exquisite combination of hetreometallic [TbIIINiII(COO)3(H2O)] clusters with a designed hexatopic ligand generates one highly robust three-dimensional heterometallic TbIII/NiII-organic framework material {[TbNi(HTDP)(H2O)] 3DMF 2H2O}n (NUC-2; H6TDP = 2,4,6-tri(2,4-dicarboxyphenyl)pyridine). Terbium 45-50 cell division cycle 27 Homo sapiens 240-245 32033581-11 2020 There were significant changes in the mean CD4+ and CD8+ T cell counts after the course of anti-TB treatment in both groups of patients(p < 0.05). Terbium 96-98 CD4 molecule Homo sapiens 43-46 32033581-11 2020 There were significant changes in the mean CD4+ and CD8+ T cell counts after the course of anti-TB treatment in both groups of patients(p < 0.05). Terbium 96-98 CD8a molecule Homo sapiens 52-55 32033581-13 2020 CONCLUSION: We found significantly lower CD4+ T cell counts among TB infected HIV negative patients compared with controls who showed that TB was the cause of non-HIV-associated declination of circulating CD4 counts, and the reduction was reversible with anti-tubercular treatment in both HIV-negative and ART naive TB-HIV co-infected patients. Terbium 66-68 CD4 molecule Homo sapiens 41-44 32033581-13 2020 CONCLUSION: We found significantly lower CD4+ T cell counts among TB infected HIV negative patients compared with controls who showed that TB was the cause of non-HIV-associated declination of circulating CD4 counts, and the reduction was reversible with anti-tubercular treatment in both HIV-negative and ART naive TB-HIV co-infected patients. Terbium 66-68 CD4 molecule Homo sapiens 205-208 31472402-4 2020 TB-KDM individuals exhibit significantly higher levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-1alpha, IL-1beta and IL-6 in comparison to TB-NDM, TB alone and DM alone individuals. Terbium 0-2 interferon gamma Homo sapiens 58-66 31472402-4 2020 TB-KDM individuals exhibit significantly higher levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-1alpha, IL-1beta and IL-6 in comparison to TB-NDM, TB alone and DM alone individuals. Terbium 0-2 interleukin 2 Homo sapiens 68-72 31472402-4 2020 TB-KDM individuals exhibit significantly higher levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-1alpha, IL-1beta and IL-6 in comparison to TB-NDM, TB alone and DM alone individuals. Terbium 0-2 tumor necrosis factor Homo sapiens 74-82 31472402-4 2020 TB-KDM individuals exhibit significantly higher levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-1alpha, IL-1beta and IL-6 in comparison to TB-NDM, TB alone and DM alone individuals. Terbium 0-2 interleukin 17A Homo sapiens 84-90 31472402-4 2020 TB-KDM individuals exhibit significantly higher levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-1alpha, IL-1beta and IL-6 in comparison to TB-NDM, TB alone and DM alone individuals. Terbium 0-2 interleukin 1 alpha Homo sapiens 92-101 31472402-4 2020 TB-KDM individuals exhibit significantly higher levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-1alpha, IL-1beta and IL-6 in comparison to TB-NDM, TB alone and DM alone individuals. Terbium 0-2 interleukin 1 beta Homo sapiens 103-111 31472402-4 2020 TB-KDM individuals exhibit significantly higher levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-1alpha, IL-1beta and IL-6 in comparison to TB-NDM, TB alone and DM alone individuals. Terbium 0-2 interleukin 6 Homo sapiens 116-120 31472402-7 2020 TB-NDM individuals are also characterized by significantly diminished TB-antigen stimulated levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-17F, IL-1alpha, IL-1beta and/or IL-6 at pre-treatment and at 2 months of ATT and IFNgamma, IL-2, IL-1alpha and IL-1beta at post-treatment. Terbium 0-2 interferon gamma Homo sapiens 102-110 31472402-7 2020 TB-NDM individuals are also characterized by significantly diminished TB-antigen stimulated levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-17F, IL-1alpha, IL-1beta and/or IL-6 at pre-treatment and at 2 months of ATT and IFNgamma, IL-2, IL-1alpha and IL-1beta at post-treatment. Terbium 0-2 interleukin 2 Homo sapiens 112-116 31472402-7 2020 TB-NDM individuals are also characterized by significantly diminished TB-antigen stimulated levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-17F, IL-1alpha, IL-1beta and/or IL-6 at pre-treatment and at 2 months of ATT and IFNgamma, IL-2, IL-1alpha and IL-1beta at post-treatment. Terbium 0-2 tumor necrosis factor Homo sapiens 118-126 31472402-7 2020 TB-NDM individuals are also characterized by significantly diminished TB-antigen stimulated levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-17F, IL-1alpha, IL-1beta and/or IL-6 at pre-treatment and at 2 months of ATT and IFNgamma, IL-2, IL-1alpha and IL-1beta at post-treatment. Terbium 0-2 interleukin 17A Homo sapiens 128-134 31472402-7 2020 TB-NDM individuals are also characterized by significantly diminished TB-antigen stimulated levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-17F, IL-1alpha, IL-1beta and/or IL-6 at pre-treatment and at 2 months of ATT and IFNgamma, IL-2, IL-1alpha and IL-1beta at post-treatment. Terbium 0-2 interleukin 17F Homo sapiens 136-142 31472402-7 2020 TB-NDM individuals are also characterized by significantly diminished TB-antigen stimulated levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-17F, IL-1alpha, IL-1beta and/or IL-6 at pre-treatment and at 2 months of ATT and IFNgamma, IL-2, IL-1alpha and IL-1beta at post-treatment. Terbium 0-2 interleukin 1 alpha Homo sapiens 144-153 31472402-7 2020 TB-NDM individuals are also characterized by significantly diminished TB-antigen stimulated levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-17F, IL-1alpha, IL-1beta and/or IL-6 at pre-treatment and at 2 months of ATT and IFNgamma, IL-2, IL-1alpha and IL-1beta at post-treatment. Terbium 0-2 interleukin 1 beta Homo sapiens 155-163 31472402-7 2020 TB-NDM individuals are also characterized by significantly diminished TB-antigen stimulated levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-17F, IL-1alpha, IL-1beta and/or IL-6 at pre-treatment and at 2 months of ATT and IFNgamma, IL-2, IL-1alpha and IL-1beta at post-treatment. Terbium 0-2 interleukin 6 Homo sapiens 171-175 31472402-7 2020 TB-NDM individuals are also characterized by significantly diminished TB-antigen stimulated levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-17F, IL-1alpha, IL-1beta and/or IL-6 at pre-treatment and at 2 months of ATT and IFNgamma, IL-2, IL-1alpha and IL-1beta at post-treatment. Terbium 0-2 interferon gamma Homo sapiens 221-229 31472402-7 2020 TB-NDM individuals are also characterized by significantly diminished TB-antigen stimulated levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-17F, IL-1alpha, IL-1beta and/or IL-6 at pre-treatment and at 2 months of ATT and IFNgamma, IL-2, IL-1alpha and IL-1beta at post-treatment. Terbium 0-2 interleukin 2 Homo sapiens 231-235 31472402-7 2020 TB-NDM individuals are also characterized by significantly diminished TB-antigen stimulated levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-17F, IL-1alpha, IL-1beta and/or IL-6 at pre-treatment and at 2 months of ATT and IFNgamma, IL-2, IL-1alpha and IL-1beta at post-treatment. Terbium 0-2 interleukin 1 alpha Homo sapiens 237-246 31472402-7 2020 TB-NDM individuals are also characterized by significantly diminished TB-antigen stimulated levels of IFNgamma, IL-2, TNFalpha, IL-17A, IL-17F, IL-1alpha, IL-1beta and/or IL-6 at pre-treatment and at 2 months of ATT and IFNgamma, IL-2, IL-1alpha and IL-1beta at post-treatment. Terbium 0-2 interleukin 1 beta Homo sapiens 251-259 32265867-12 2020 This study provides new insight into GreA as a potential target in multi-drug resistant TB treatment. Terbium 88-90 transcription elongation factor GreA Mycobacterium tuberculosis H37Rv 37-41 32197582-7 2020 RESULTS: Of 103 ascites fluid samples collected, 52 of them (50.5%) had an elevated ADA, consistent with a presumptive diagnosis of peritoneal TB. Terbium 143-145 adenosine deaminase Homo sapiens 84-87 32067022-2 2020 The MSN-Tb-UbR exhibits ratiometric sensing ability for DUB (UCH-L1) with good sensitivity and selectivity. Terbium 8-10 ubiquitin C-terminal hydrolase L1 Homo sapiens 61-67 32164621-7 2020 RESULTS: In this 78 patient cohort, high TB was significantly associated with advanced tumor status (pT4: 50.0% vs 22.2%, p = 0.007, pN1/2: 70.8% vs 39.6%, p = 0.011, M1: 20.8% vs 1.9%) and higher histological grade (G3: 25.0% vs 5.7%, p = 0.014). Terbium 41-43 serpin family E member 2 Homo sapiens 133-138 32383705-4 2020 Hormonal changes in T2-D also may increase susceptibility to TB, including 2 hormones -ghrelin and leptin that are involved to in controlling blood glucose levels related to malnutrition during TB. Terbium 61-63 leptin Homo sapiens 99-105 32224537-12 2020 CONCLUSION: Evaluation of immune status based on PD-L1 pleural concentration and Th2 to Th1 ratio might predict the risk of MDR-TB occurrence. Terbium 128-130 negative elongation factor complex member C/D Homo sapiens 88-91 31538348-5 2020 The TB score correlated significantly with sex, Lauren phenotype, pT-, pN- and M categories, histological grade, R status; and lymph node ratio, lymphatic invasion, perineural invasion and HER2-, MET- and MSI status. Terbium 4-6 erb-b2 receptor tyrosine kinase 2 Homo sapiens 189-193 31538348-5 2020 The TB score correlated significantly with sex, Lauren phenotype, pT-, pN- and M categories, histological grade, R status; and lymph node ratio, lymphatic invasion, perineural invasion and HER2-, MET- and MSI status. Terbium 4-6 SAFB like transcription modulator Homo sapiens 196-199 31945300-3 2020 OBJECTIVE: Define the optimal dose of isoniazid for patients with isoniazid-resistant TB mediated by inhA mutations. Terbium 86-88 inhibin subunit alpha Homo sapiens 101-105 31821340-0 2019 IL-18/IL-37/IP-10 signalling complex as a potential biomarker for discriminating active and latent TB. Terbium 99-101 interleukin 18 Homo sapiens 0-5 31875422-8 2020 However, in STN and TB percent PAX7-positive cells were decreased compared with CON (P < 0.05). Terbium 20-22 paired box protein Pax-7 Ovis aries 31-35 31821340-0 2019 IL-18/IL-37/IP-10 signalling complex as a potential biomarker for discriminating active and latent TB. Terbium 99-101 interleukin 37 Homo sapiens 6-11 31821340-0 2019 IL-18/IL-37/IP-10 signalling complex as a potential biomarker for discriminating active and latent TB. Terbium 99-101 C-X-C motif chemokine ligand 10 Homo sapiens 12-17 31797893-7 2019 The TNF-alpha levels showed a significant positive correlation with TB SUVmax (rho = 0.220 and p = 0.018) and TB SUVmean (rho = 0.250 and p = 0.007). Terbium 68-70 tumor necrosis factor Homo sapiens 4-13 31797893-7 2019 The TNF-alpha levels showed a significant positive correlation with TB SUVmax (rho = 0.220 and p = 0.018) and TB SUVmean (rho = 0.250 and p = 0.007). Terbium 110-112 tumor necrosis factor Homo sapiens 4-13 31454491-10 2019 In conclusion, IFN-gamma/IL-2 FluoroSpot assay is conducive for the diagnosis of ATB in patients with positive T-SPOT.TB results. Terbium 82-84 interferon gamma Homo sapiens 15-24 31454491-10 2019 In conclusion, IFN-gamma/IL-2 FluoroSpot assay is conducive for the diagnosis of ATB in patients with positive T-SPOT.TB results. Terbium 82-84 interleukin 2 Homo sapiens 25-29 31252187-7 2019 Furthermore, the hepcidin level showed a negative correlation with spot numbers in the positive control wells of the T-SPOT.TB assay; thus the effect of the peptide on interferon-gamma production in T cells was explored. Terbium 124-126 hepcidin antimicrobial peptide Homo sapiens 17-25 31625291-7 2019 Participants were tested with tuberculin skin test (TST) and T-SPOT.TB (an interferon gamma release assay) simultaneously. Terbium 68-70 interferon gamma Homo sapiens 75-91 31625291-14 2019 However, in participants with CD4+ < 200 cells/mm3, T-SPOT.TB detected more latent tuberculosis infections than the TST. Terbium 59-61 CD4 molecule Homo sapiens 30-33 31377576-8 2019 In addition, the biosensor was able to detect IFN-gamma in serum samples successfully, which is expected to provide an efficient method for TB diagnosis at early stages. Terbium 140-142 interferon gamma Homo sapiens 46-55 31112308-5 2019 Micro-CT analysis of femurs and vertebrae of Cldn-11 knock-out (KO) mice at 12 weeks of age exhibited a 40% (p < 0.01) reduction in Tb bone volume adjusted for tissue volume compared with control mice, a change caused by significant reductions in Tb number and thickness and increase in Tb separation. Terbium 135-137 claudin 11 Mus musculus 45-52 31112308-5 2019 Micro-CT analysis of femurs and vertebrae of Cldn-11 knock-out (KO) mice at 12 weeks of age exhibited a 40% (p < 0.01) reduction in Tb bone volume adjusted for tissue volume compared with control mice, a change caused by significant reductions in Tb number and thickness and increase in Tb separation. Terbium 250-252 claudin 11 Mus musculus 45-52 31112308-5 2019 Micro-CT analysis of femurs and vertebrae of Cldn-11 knock-out (KO) mice at 12 weeks of age exhibited a 40% (p < 0.01) reduction in Tb bone volume adjusted for tissue volume compared with control mice, a change caused by significant reductions in Tb number and thickness and increase in Tb separation. Terbium 250-252 claudin 11 Mus musculus 45-52 31112308-6 2019 Histomorphometry and serum biomarker studies revealed that reduced bone formation, not increased resorption, is the cause for reduced Tb bone volume in the Cldn-11 KO mice. Terbium 134-136 claudin 11 Mus musculus 156-163 31525214-16 2019 TB positivity rate was 67.8%, 49.3%, 24.3%, and 14.5% using cytology, Xpert MTB/RIF, Auramine O (FM) microscopy, and Ziehl Nelson (ZN) microscopy, respectively. Terbium 0-2 ras homolog family member F, filopodia associated Homo sapiens 80-83 31215255-8 2019 Serum HPA levels were significantly higher in patients with high TB than low TB [250.1 (188.5-338.1) vs. 173.6 (134.3-219.8) pg/mL] (p < 0.001). Terbium 65-67 heparanase Homo sapiens 6-9 31215255-8 2019 Serum HPA levels were significantly higher in patients with high TB than low TB [250.1 (188.5-338.1) vs. 173.6 (134.3-219.8) pg/mL] (p < 0.001). Terbium 77-79 heparanase Homo sapiens 6-9 31215255-10 2019 In multiple logistic regression analysis HPA was a predictor of high TB. Terbium 69-71 heparanase Homo sapiens 41-44 31215255-11 2019 Conclusion: Elevated HPA level in patients with STEMI is related to high TB. Terbium 73-75 heparanase Homo sapiens 21-24 31586142-7 2019 This study shows that genetic polymorphisms of NRF2, MAFF and MAFK may contribute to the susceptibility to ATLI in the Chinese anti-TB treatment population. Terbium 132-134 NFE2 like bZIP transcription factor 2 Homo sapiens 47-51 31586142-7 2019 This study shows that genetic polymorphisms of NRF2, MAFF and MAFK may contribute to the susceptibility to ATLI in the Chinese anti-TB treatment population. Terbium 132-134 MAF bZIP transcription factor F Homo sapiens 53-57 31586142-7 2019 This study shows that genetic polymorphisms of NRF2, MAFF and MAFK may contribute to the susceptibility to ATLI in the Chinese anti-TB treatment population. Terbium 132-134 MAF bZIP transcription factor K Homo sapiens 62-66 31625364-1 2019 BACKGROUND: Interferon-gamma release assay (T-SPOT.TB) has the theoretical possibility of discriminating TB from most non-tuberculous mycobacteria (NTM) infections, but there are limited reports on the use of T-SPOT.TB for diseases due to NTM in high TB burden country. Terbium 51-53 interferon gamma Homo sapiens 12-28 31625364-1 2019 BACKGROUND: Interferon-gamma release assay (T-SPOT.TB) has the theoretical possibility of discriminating TB from most non-tuberculous mycobacteria (NTM) infections, but there are limited reports on the use of T-SPOT.TB for diseases due to NTM in high TB burden country. Terbium 105-107 interferon gamma Homo sapiens 12-28 31247363-5 2019 The combined use of TB and 0.4 g/g TSS APG achieved the maximal activities of protease (1.8) and alpha-glucosidase (1.9), and the activities of protease and alpha-glucosidase were positively correlated to the dosage of APG. Terbium 20-22 sucrase-isomaltase Homo sapiens 97-114 31247363-5 2019 The combined use of TB and 0.4 g/g TSS APG achieved the maximal activities of protease (1.8) and alpha-glucosidase (1.9), and the activities of protease and alpha-glucosidase were positively correlated to the dosage of APG. Terbium 20-22 sucrase-isomaltase Homo sapiens 157-174 31261245-10 2019 We report one known false negative, in a patient who developed disseminated TB on anti-TNF therapy. Terbium 76-78 tumor necrosis factor Homo sapiens 87-90 31075739-4 2019 The CASN-P2:mu-calpain ratio at day 0 was greater for TB, which presented lesser calpain autolysis, myofibrillar protein degradation, and fewer sarcoplasmic proteome changes during aging. Terbium 54-56 calpastatin Bos taurus 4-8 31352780-3 2019 We report the synthesis and physical characterization of an S4 symmetric, four-coordinate tetravalent terbium complex, [Tb(NP(1,2-bis-tBu-diamidoethane)(NEt2))4] (where Et is ethyl and tBu is tert-butyl). Terbium 102-109 tetraspanin 12 Homo sapiens 153-157 31352780-4 2019 The ligand field in this complex is weak and the metal-ligand bonds sufficiently covalent so that the tetravalent terbium ion is stable and accessible via a mild oxidant from the anionic, trivalent, terbium precursor, [(Et2O)K][Tb(NP(1,2-bis-tBu-diamidoethane)(NEt2))4]. Terbium 114-121 tetraspanin 12 Homo sapiens 261-265 31352780-7 2019 Magnetic susceptibility, electron paramagnetic resonance (EPR) spectroscopy, X-ray absorption near-edge spectroscopy (XANES), and density functional theory studies indicate a 4f7 ground state for [Tb(NP(1,2-bis-tBu-diamidoethane)(NEt2))4] with considerable zero-field splitting, demonstrating that magnetic, tetravalent lanthanide ions engage in covalent metal-ligand bonds. Terbium 197-199 tetraspanin 12 Homo sapiens 230-234 31268768-0 2019 End TB Strategy: Time to Move on From the Skin Test to the Interferon-gamma Release Assays. Terbium 4-6 interferon gamma Homo sapiens 59-75 31227345-4 2019 Herein, we report novel N-methyl carbazole derivatives as potential anti-TB compounds acting directly via InhA inhibition. Terbium 73-75 NADH-dependent enoyl-[ACP] reductase Mycobacterium tuberculosis H37Rv 106-110 30776144-4 2019 The present study aimed to investigate the associations between HMOX1 and NQO1 polymorphisms and ATLI in Chinese anti-TB treatment population. Terbium 118-120 heme oxygenase 1 Homo sapiens 64-69 30776144-4 2019 The present study aimed to investigate the associations between HMOX1 and NQO1 polymorphisms and ATLI in Chinese anti-TB treatment population. Terbium 118-120 NAD(P)H quinone dehydrogenase 1 Homo sapiens 74-78 30776144-9 2019 WHAT IS NEW AND CONCLUSION: This is the first study to explore the relationship between HMOX1, NQO1 polymorphisms and ATLI in Chinese anti-TB treatment population. Terbium 139-141 heme oxygenase 1 Homo sapiens 88-93 30776144-9 2019 WHAT IS NEW AND CONCLUSION: This is the first study to explore the relationship between HMOX1, NQO1 polymorphisms and ATLI in Chinese anti-TB treatment population. Terbium 139-141 NAD(P)H quinone dehydrogenase 1 Homo sapiens 95-99 30986485-4 2019 A cytokeratin AE1/AE3 immunostaining was applied to identify and quantify TB by the "hot-spot" method. Terbium 74-76 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 14-17 30638734-1 2019 BACKGROUND AND PURPOSE: We aimed to estimate TB prevalence among in-patients hospitalized with acute lower respiratory infection (ALRI) through a routine TB case finding approach (Patient-Initiated-Pathway, PIP) and among those without initial TB detection by PIP using a supplementary-Intensified-Case-Finding (supplementary-ICF) approach to determine the extent of active TB infection in patients enrolled in population-based surveillance in Sa Keao, Thailand. Terbium 45-47 prolactin induced protein Homo sapiens 260-263 30638734-8 2019 RESULTS: TB prevalence among ALRI hospitalized patients was 12.2% among those undergoing PIP and 6.8% among those undergoing supplementary-ICF. Terbium 9-11 prolactin induced protein Homo sapiens 89-92 31413362-3 2019 There is also an important positive feedback loop as Tb influences BMR1-3. Terbium 53-55 bone morphogenetic protein receptor type 2 Homo sapiens 67-73 30986485-4 2019 A cytokeratin AE1/AE3 immunostaining was applied to identify and quantify TB by the "hot-spot" method. Terbium 74-76 solute carrier family 4 member 3 Homo sapiens 18-21 31357953-13 2019 CONCLUSIONS: In T-SPOT.TB-assisted diagnosis of patients with active tuberculosis, previous treatment, decreased CD4+ and platelet count might lead to the decreased SFCs to ESAT-6, decreased alpha-2 globulin and high platelet distribution width might lead to the decreased SFCs to CFP-10, decreased albumin-globulin ratio, CD4+ and CD8+ might lead to an increase in the false negative rate of the T-SPOT.TB. Terbium 23-25 CD4 molecule Homo sapiens 113-116 31357953-13 2019 CONCLUSIONS: In T-SPOT.TB-assisted diagnosis of patients with active tuberculosis, previous treatment, decreased CD4+ and platelet count might lead to the decreased SFCs to ESAT-6, decreased alpha-2 globulin and high platelet distribution width might lead to the decreased SFCs to CFP-10, decreased albumin-globulin ratio, CD4+ and CD8+ might lead to an increase in the false negative rate of the T-SPOT.TB. Terbium 23-25 CD4 molecule Homo sapiens 323-326 31357953-13 2019 CONCLUSIONS: In T-SPOT.TB-assisted diagnosis of patients with active tuberculosis, previous treatment, decreased CD4+ and platelet count might lead to the decreased SFCs to ESAT-6, decreased alpha-2 globulin and high platelet distribution width might lead to the decreased SFCs to CFP-10, decreased albumin-globulin ratio, CD4+ and CD8+ might lead to an increase in the false negative rate of the T-SPOT.TB. Terbium 404-406 CD4 molecule Homo sapiens 113-116 30720667-9 2019 On the basis of this case-control study, SNP rs10946737 in FAM65B may be associated with susceptibility to ATDH in Chinese Han anti-TB treatment patients. Terbium 132-134 RHO family interacting cell polarization regulator 2 Homo sapiens 59-65 31439177-3 2019 IL-6 screening of patients with TB may be useful to monitor the progress of infection and to infer the risk of progression to active disease. Terbium 32-34 interleukin 6 Homo sapiens 0-4 30817003-9 2019 Based on this 1:2 matched case-control study, the AA genotype of rs4430924 in XPO1 may be associated with higher risk of anti-TB drug-induced hepatotoxicity in Chinese anti-TB treatment patients. Terbium 126-128 exportin 1 Homo sapiens 78-82 30817003-9 2019 Based on this 1:2 matched case-control study, the AA genotype of rs4430924 in XPO1 may be associated with higher risk of anti-TB drug-induced hepatotoxicity in Chinese anti-TB treatment patients. Terbium 173-175 exportin 1 Homo sapiens 78-82 30973098-4 2019 Interferon gamma (IFN-gamma) assays are a reliable detection method for TB in other animal species, and studies have indicated that these tests can be used in white rhinoceros. Terbium 72-74 interferon gamma Equus caballus 18-27 31248116-4 2019 The applicability of these electrode chips in bioaffinity assays was demonstrated by an immunoassay of human C-reactive protein (i) using Tb(III) chelate label displaying long-lived hot electron-induced electrochemiluminescence (HECL) and (ii) now for the first time fluorescein isothiocyanate (FITC) was utilized as an a low-cost organic label displaying a short-lived HECL in a real-world bioaffinity assay. Terbium 138-140 C-reactive protein Homo sapiens 109-127 31211376-9 2019 Mitochondrial density (CS) was higher for SB and TB than QH (P <= 0.0007). Terbium 49-51 citrate synthase Equus caballus 23-25 31100646-4 2019 LGR5 expression was evaluated by RNAscope, a newly developed RNA in situ hybridization technique, using a tissue microarray consisting of 55 patient samples of TB in colon adenocarcinoma (CA) selected from the medical archives at our hospital. Terbium 160-162 leucine rich repeat containing G protein-coupled receptor 5 Homo sapiens 0-4 31066103-7 2019 The compounds R7, R12, R17, R18, R19, R20 were found to be more potent as anti-TB agents than ethambutol (MIC 3.125 mug/ml). Terbium 79-81 G protein-coupled receptor 17 Homo sapiens 18-21 31270533-9 2019 Mitochondrial density (CS) was higher for SB and TB than QH (P <= 0.0007). Terbium 49-51 citrate synthase Equus caballus 23-25 30905632-2 2019 QuantiFERON -TB Gold Plus (QFT-Plus) has two TB-specific antigens tubes (TB1 and TB2). Terbium 13-15 receptor accessory protein 5 Homo sapiens 81-84 31331525-5 2019 In the E2(-) group exposed to 27 C, the change in Tb in rats applied cinnamaldehyde was significantly lower than that of rats applied vehicle. Terbium 51-53 dihydrolipoamide S-succinyltransferase Rattus norvegicus 7-9 31190914-2 2019 We investigate the diagnostic significance of IDO as a potential biomarker to discriminate MDR patients among the TB patients. Terbium 114-116 indoleamine 2,3-dioxygenase 1 Homo sapiens 46-49 31133658-6 2019 Based on colony forming unit analysis, motif Pep-H led to killing of more than 90% M. tb in vitro at 10 mug/ml, whereas, similar activity against intracellularly growing M. tb was observed at 5 mug/ml only. Terbium 86-88 prolyl endopeptidase Homo sapiens 45-48 31133658-6 2019 Based on colony forming unit analysis, motif Pep-H led to killing of more than 90% M. tb in vitro at 10 mug/ml, whereas, similar activity against intracellularly growing M. tb was observed at 5 mug/ml only. Terbium 173-175 prolyl endopeptidase Homo sapiens 45-48 30660613-3 2019 Recently, we reported that TB cells are sensitive to the cytotoxic effects of beta-amyloid peptides, activating the cytosolic phospholipase A2. Terbium 27-29 phospholipase A2 group IVA Homo sapiens 116-142 31190914-6 2019 Results: We found that plasma IDO activity was significantly higher in the MDR-TB patients than in the DS-TB patients (p=0.012) and in the LC patients (p=0.003). Terbium 79-81 indoleamine 2,3-dioxygenase 1 Homo sapiens 30-33 31190914-7 2019 We evaluated the diagnostic significance of plasma IDO activity in discriminating the MDR-TB group from the DS-TB group using a receiver operating characteristic (ROC) curve. Terbium 90-92 indoleamine 2,3-dioxygenase 1 Homo sapiens 51-54 31190914-9 2019 Plasma IDO activity was higher in cavity cases than in non-cavity cases (p=0.042), proving a positive correlation between lung cavity number and cavity size (p<0.05, separately) among all the TB patients studied. Terbium 195-197 indoleamine 2,3-dioxygenase 1 Homo sapiens 7-10 31103419-5 2019 On specific stimulation of PFMCs with Ag85A, expression of RANTES was significantly lower in TB compared to NTB patients. Terbium 93-95 C-C motif chemokine ligand 5 Homo sapiens 59-65 30451374-11 2019 The phosphorylated mTOR levels in the liver and brain were significantly lower in TB rats than in CN rats. Terbium 82-84 mechanistic target of rapamycin kinase Rattus norvegicus 19-23 30988761-9 2019 TB and SA treatment in Abeta25-35-induced SH-SY5Y cells resulted in the restoration of cell morphology, an increase of SOD and GSH-Px activity, a decrease in ROS, Ca2+ and MDA content, and a decrease in Calnexin expression. Terbium 0-2 carbonic anhydrase 2 Homo sapiens 163-166 30988761-9 2019 TB and SA treatment in Abeta25-35-induced SH-SY5Y cells resulted in the restoration of cell morphology, an increase of SOD and GSH-Px activity, a decrease in ROS, Ca2+ and MDA content, and a decrease in Calnexin expression. Terbium 0-2 calnexin Homo sapiens 203-211 30988761-13 2019 As potential AD treatment drugs, SA and TB compounds have been demonstrated to alleviate the oxidative stress induced by Abeta25-35 via the regulation of intracellular calcium homeostasis and Calnexin, preventing AD development. Terbium 40-42 calnexin Mus musculus 192-200 31103419-6 2019 We also observed increased expression of T regs and PD1 on CD8+T cells in PFMC of TB patients. Terbium 82-84 MHC class I antigen 1 Sus scrofa 52-55 31103419-10 2019 The observations necessitate further studies to investigate the levels of RANTES for its potential biological relevance in TB immunity and its use as a biomarker for diagnosis of pleural TB. Terbium 123-125 C-C motif chemokine ligand 5 Homo sapiens 74-80 31022273-11 2019 Though these patterns were less pronounced in CD3-CD8lo lymphocytes, the percentage of KLRG1+ cells was higher in TB-IRIS patients prior to ART (p<=0.043). Terbium 114-116 killer cell lectin like receptor G1 Homo sapiens 87-92 31039752-8 2019 CONCLUSIONS: There was increased macrophage expression of VDR after stimulation with live M. tuberculosis in persons with previous extrapulmonary TB. Terbium 146-148 vitamin D receptor Homo sapiens 58-61 31039752-9 2019 If post-treatment VDR expression reflects expression prior to disease, it may identify persons at risk for extrapulmonary TB. Terbium 122-124 vitamin D receptor Homo sapiens 18-21 31022273-15 2019 Since a dysfunctional CD8+ lymphocyte compartment could predispose patients to TB-IRIS, the functional role of these cells prior to TB-IRIS development should be further explored. Terbium 79-81 CD8a molecule Homo sapiens 22-25 31105511-9 2019 However, in the dynamic FC analysis, post-TBS showed reduced FC in the left angular and PCC in the early windows, and in the following windows, increased FC in multiple cortical areas including bilateral pre- and postcentral gyri and paracentral lobule and non-sensorimotor areas including the prefrontal, temporal and occipital gyrus, and brain stem. Terbium 42-45 crystallin gamma D Homo sapiens 88-91 30827373-0 2019 Simultaneous measurement of antigen-induced CXCL10 and IFN-gamma enhances test sensitivity for bovine TB detection in cattle. Terbium 102-104 C-X-C motif chemokine ligand 10 Bos taurus 44-50 30786125-0 2019 High Blocking Temperature of Magnetization and Giant Coercivity in the Azafullerene Tb2 @C79 N with a Single-Electron Terbium-Terbium Bond. Terbium 118-125 receptor accessory protein 5 Homo sapiens 84-87 30786125-0 2019 High Blocking Temperature of Magnetization and Giant Coercivity in the Azafullerene Tb2 @C79 N with a Single-Electron Terbium-Terbium Bond. Terbium 126-133 receptor accessory protein 5 Homo sapiens 84-87 31024518-8 2019 Additionally, the frequency of IL-17-expressing CD4+ T cells, predominately with single-positive IL-17+ and double-positive IL-2+/IL-17+ phenotypes, was higher in participants with active TB than in the other two groups. Terbium 188-190 interleukin 17A Homo sapiens 31-36 30506122-8 2019 RESULTS: Eight SNPs of CD53 were found to be associated with TB case. Terbium 61-63 CD53 molecule Homo sapiens 23-27 30684743-6 2019 The present study analysed secreted BiP from plasma samples collected from healthy participants and patients with newly diagnosed tuberculosis (TBdx), seen over the course of TB treatment at week 1 (W1), month 2 (M2), and month 6 (M6). Terbium 144-146 heat shock protein family A (Hsp70) member 5 Homo sapiens 36-39 30684743-7 2019 The results revealed that during the initial TB disease and treatment period, cells are subjected to stress conditions resulting in metabolic shifts, which lead to the secretion of the intracellular UPR-mediating chaperone protein, BiP. Terbium 45-47 heat shock protein family A (Hsp70) member 5 Homo sapiens 232-235 30684743-10 2019 Analysis of paired time-point visits revealed increased BiP secretion during early TB treatment. Terbium 83-85 heat shock protein family A (Hsp70) member 5 Homo sapiens 56-59 30684743-11 2019 The detection of BiP in plasma samples was found to decrease after successful TB treatment to levels comparable to those in the healthy controls. Terbium 78-80 heat shock protein family A (Hsp70) member 5 Homo sapiens 17-20 30684743-12 2019 Evaluation of BiP levels in larger TB treatment studies may lead to the identification of a new target for early TB diagnosis and host-directed immunotherapy. Terbium 35-37 heat shock protein family A (Hsp70) member 5 Homo sapiens 14-17 30684743-12 2019 Evaluation of BiP levels in larger TB treatment studies may lead to the identification of a new target for early TB diagnosis and host-directed immunotherapy. Terbium 113-115 heat shock protein family A (Hsp70) member 5 Homo sapiens 14-17 30623240-8 2019 We demonstrated that both TB1 and TB2 induce a higher expression of CD25+CD134+ markers on CD4+ T cells among infected TB subjects, compared to the lower degree of CD8+ T cells, mainly induced to TB2 stimulation. Terbium 26-28 receptor accessory protein 5 Homo sapiens 196-199 30604272-13 2019 TB showed loss of ER (p < 0.0001) and PR (p < 0.0001), reduced E-cadherin (p < 0.0001) expression, and aberrant beta-catenin expression (p = 0.042). Terbium 0-2 cadherin 1 Homo sapiens 69-79 30604272-13 2019 TB showed loss of ER (p < 0.0001) and PR (p < 0.0001), reduced E-cadherin (p < 0.0001) expression, and aberrant beta-catenin expression (p = 0.042). Terbium 0-2 catenin beta 1 Homo sapiens 121-133 30889894-6 2019 Moreover, TB supplementation increased gene expression of PGC-1alpha and SIRT1, involved in muscle biogenesis and function. Terbium 10-12 PPARG coactivator 1 alpha Rattus norvegicus 58-68 30889894-6 2019 Moreover, TB supplementation increased gene expression of PGC-1alpha and SIRT1, involved in muscle biogenesis and function. Terbium 10-12 sirtuin 1 Rattus norvegicus 73-78 30889894-7 2019 These results suggested that TB might attenuate obesity-induced inflammation and mitochondrial dysfunction by modulating adipose tissue inflammation and the muscle PGC-1alpha/SIRT1 pathway. Terbium 29-31 PPARG coactivator 1 alpha Rattus norvegicus 164-174 30889894-7 2019 These results suggested that TB might attenuate obesity-induced inflammation and mitochondrial dysfunction by modulating adipose tissue inflammation and the muscle PGC-1alpha/SIRT1 pathway. Terbium 29-31 sirtuin 1 Rattus norvegicus 175-180 30841876-8 2019 The median MIF levels in patients with advanced disease, disseminated and drug-resistant TB were significantly higher than that observed in mild -to- moderate disease, non-disseminated and drug-sensitive TB. Terbium 89-91 macrophage migration inhibitory factor Homo sapiens 11-14 30841876-8 2019 The median MIF levels in patients with advanced disease, disseminated and drug-resistant TB were significantly higher than that observed in mild -to- moderate disease, non-disseminated and drug-sensitive TB. Terbium 204-206 macrophage migration inhibitory factor Homo sapiens 11-14 30427060-4 2019 During longitudinal follow up, sCD14, CRP and sTF levels remained significantly increased in TB-DM compared with TB from baseline (pre-treatment), during treatment (2nd month) and at the completion (6th month) of anti-TB treatment (ATT), whereas sCD163 was significantly higher in TB-DM compared with TB only at baseline. Terbium 93-95 C-reactive protein Homo sapiens 38-41 30827373-0 2019 Simultaneous measurement of antigen-induced CXCL10 and IFN-gamma enhances test sensitivity for bovine TB detection in cattle. Terbium 102-104 interferon gamma Bos taurus 55-64 30657312-3 2019 Here, we demonstrate the implementation of time-gated Forster resonance energy transfer (TG-FRET) between terbium donors and dye acceptors into HCR for multiplexed quantification of microRNAs (miR-20a and miR-21) and their DNA analogues. Terbium 106-113 microRNA 20a Homo sapiens 193-200 30657312-3 2019 Here, we demonstrate the implementation of time-gated Forster resonance energy transfer (TG-FRET) between terbium donors and dye acceptors into HCR for multiplexed quantification of microRNAs (miR-20a and miR-21) and their DNA analogues. Terbium 106-113 microRNA 21 Homo sapiens 205-211 30728405-6 2019 Moreover, there was an expansion and functional restoration of central memory (CD27+CD45RO+) CXCR3+CCR6- CD4+ lymphocytes and corresponding cytokines, with reduction in CXCR3-CCR6+ cells after ART initiation only in those who developed TB-IRIS. Terbium 236-238 C-C motif chemokine receptor 6 Homo sapiens 99-103 30586869-5 2018 Moreover, we found that TB and bortezomib up-regulated p62/Sequestosome1(p62/SQSTM1) protein, while metformin and quercetin down-regulated it. Terbium 24-26 sequestosome 1 Homo sapiens 77-83 30076971-8 2019 IP-10 sensitivity/specificity in TB vs. non-TB studies was 85%/63% and in TB and HIV coinfected vs. other lung conditions 94%/21%. Terbium 33-35 C-X-C motif chemokine ligand 10 Homo sapiens 0-5 30076971-8 2019 IP-10 sensitivity/specificity in TB vs. non-TB studies was 85%/63% and in TB and HIV coinfected vs. other lung conditions 94%/21%. Terbium 44-46 C-X-C motif chemokine ligand 10 Homo sapiens 0-5 29938548-4 2019 RESULTS: Staining for CK20, TDAG51, INSM1, and stromal CD10 was significantly more common in TB cases than in BCC cases ( P < .001). Terbium 93-95 keratin 20 Homo sapiens 22-26 29938548-4 2019 RESULTS: Staining for CK20, TDAG51, INSM1, and stromal CD10 was significantly more common in TB cases than in BCC cases ( P < .001). Terbium 93-95 INSM transcriptional repressor 1 Homo sapiens 36-41 29938548-4 2019 RESULTS: Staining for CK20, TDAG51, INSM1, and stromal CD10 was significantly more common in TB cases than in BCC cases ( P < .001). Terbium 93-95 membrane metalloendopeptidase Homo sapiens 55-59 29938548-5 2019 Epithelial CD10 and AR staining was significantly more common in BCC cases than in TB cases ( P < .001). Terbium 83-85 membrane metalloendopeptidase Homo sapiens 11-15 29938548-5 2019 Epithelial CD10 and AR staining was significantly more common in BCC cases than in TB cases ( P < .001). Terbium 83-85 androgen receptor Homo sapiens 20-22 29938548-8 2019 TDAG51 showed 100% specificity for TB. Terbium 35-37 pleckstrin homology like domain family A member 1 Homo sapiens 0-6 30696859-8 2019 In mouse liver, HSF1 is regulated by the daily Tb rhythm, and acts as a circadian transcription factor. Terbium 47-49 heat shock factor 1 Mus musculus 16-20 30696859-9 2019 Taken together, chipmunks similarly use the Tb rhythm to regulate gene expression via HSF1 during the torpor-arousal cycle in the hibernation season. Terbium 44-46 heat shock factor 1 Mus musculus 86-90 30522898-3 2019 The bioassay results revealed that most of the target molecules had anti-tuberculosis (anti-TB) activity, of which 14 compounds had very strong anti-TB activity [minimum inhibitory concentration (MIC) < 2 muM]. Terbium 149-151 latexin Homo sapiens 208-211 31383594-3 2019 The present study evaluated for the first time therapeutic efficacy and tolerability of continuous TBS (cTBS) over the supplementary motor area (SMA) in treatment resistant OCD patients using a double blind, sham-controlled design. Terbium 99-102 survival of motor neuron 1, telomeric Homo sapiens 145-148 31912094-5 2019 More than half of the cases of mucinous ADK revealed an increased intensity of TB, whereas in the case of "signet ring cell" ADK, an average intensity of this phenomenon. Terbium 79-81 adenosine kinase Homo sapiens 40-43 30774540-5 2019 Technetium-99m-ethambutol (99mTc-EMB) scintigraphy can be used to detect and localize of TB. Terbium 89-91 embigin Homo sapiens 33-36 30774540-18 2019 This study showed that patient STB with suspected 99mTc-EMB scintigraphy result could be directly treated with anti-TB. Terbium 32-34 embigin Homo sapiens 56-59 30586869-5 2018 Moreover, we found that TB and bortezomib up-regulated p62/Sequestosome1(p62/SQSTM1) protein, while metformin and quercetin down-regulated it. Terbium 24-26 sequestosome 1 Homo sapiens 55-58 30586869-5 2018 Moreover, we found that TB and bortezomib up-regulated p62/Sequestosome1(p62/SQSTM1) protein, while metformin and quercetin down-regulated it. Terbium 24-26 sequestosome 1 Homo sapiens 59-72 30586869-5 2018 Moreover, we found that TB and bortezomib up-regulated p62/Sequestosome1(p62/SQSTM1) protein, while metformin and quercetin down-regulated it. Terbium 24-26 sequestosome 1 Homo sapiens 73-76 30753412-4 2019 In the current study, we report that EBI3 production by macrophages is elevated in TB patients. Terbium 83-85 Epstein-Barr virus induced 3 Homo sapiens 37-41 30682830-7 2019 Therefore, the current data provide evidence that TRPV1 channels exert an inhibitory modulation on the hypoxic drive to breathe and stimulate the Tb reduction during hypoxia. Terbium 146-148 transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus 50-55 30239753-0 2019 High efavirenz serum concentrations in TB/HIV-coinfected Ugandan adults with a CYP2B6 516 TT genotype on anti-TB treatment. Terbium 39-41 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 79-85 30586869-6 2018 p62/SQSTM1 silencing or the inhibition of NF-E2-related factor 2 (NRF2) or Heat Shock Factor 1 (HSF1), that mediate p62/SQSTM1 transcription, also reduced KSHV lytic antigen expression induced by TB or bortezomib. Terbium 196-198 sequestosome 1 Homo sapiens 0-3 30586869-6 2018 p62/SQSTM1 silencing or the inhibition of NF-E2-related factor 2 (NRF2) or Heat Shock Factor 1 (HSF1), that mediate p62/SQSTM1 transcription, also reduced KSHV lytic antigen expression induced by TB or bortezomib. Terbium 196-198 NFE2 like bZIP transcription factor 2 Homo sapiens 66-70 30586869-6 2018 p62/SQSTM1 silencing or the inhibition of NF-E2-related factor 2 (NRF2) or Heat Shock Factor 1 (HSF1), that mediate p62/SQSTM1 transcription, also reduced KSHV lytic antigen expression induced by TB or bortezomib. Terbium 196-198 heat shock transcription factor 1 Homo sapiens 96-100 30586869-7 2018 Interestingly, such combination treatments further increased intracellular ROS and cytotoxicity induced by the single TB or bortezomib treatment, suggesting that NRF2, HSF1 and p62/SQSTM1 keep the ROS level under control, allowing primary effusion lymphoma (PEL) cells to continue to survive and KSHV to replicate. Terbium 118-120 NFE2 like bZIP transcription factor 2 Homo sapiens 162-166 30586869-7 2018 Interestingly, such combination treatments further increased intracellular ROS and cytotoxicity induced by the single TB or bortezomib treatment, suggesting that NRF2, HSF1 and p62/SQSTM1 keep the ROS level under control, allowing primary effusion lymphoma (PEL) cells to continue to survive and KSHV to replicate. Terbium 118-120 heat shock transcription factor 1 Homo sapiens 168-172 30586869-7 2018 Interestingly, such combination treatments further increased intracellular ROS and cytotoxicity induced by the single TB or bortezomib treatment, suggesting that NRF2, HSF1 and p62/SQSTM1 keep the ROS level under control, allowing primary effusion lymphoma (PEL) cells to continue to survive and KSHV to replicate. Terbium 118-120 sequestosome 1 Homo sapiens 177-180 30586869-7 2018 Interestingly, such combination treatments further increased intracellular ROS and cytotoxicity induced by the single TB or bortezomib treatment, suggesting that NRF2, HSF1 and p62/SQSTM1 keep the ROS level under control, allowing primary effusion lymphoma (PEL) cells to continue to survive and KSHV to replicate. Terbium 118-120 sequestosome 1 Homo sapiens 181-187 30575787-5 2018 Importantly, pharmacological inhibition of TLR4 (Atorvastatin) reproduced the main protective effect against AT remodeling found in TLR4-/- TB mice. Terbium 140-142 toll-like receptor 4 Mus musculus 43-47 30047605-1 2018 AIMS: The aim of this study is to evaluate the potential association between N-acetyltransferase type 2 (NAT2) polymorphisms and drug-induced liver injury during anti-TB treatment (AT-DILI). Terbium 167-169 N-acetyltransferase 2 Homo sapiens 77-103 30575787-5 2018 Importantly, pharmacological inhibition of TLR4 (Atorvastatin) reproduced the main protective effect against AT remodeling found in TLR4-/- TB mice. Terbium 140-142 toll-like receptor 4 Mus musculus 132-136 30291987-7 2018 This DDA:TDB-TLR7/8 formulation offers similar vesicle characteristics to DDA:TDB (size and charge) and offers high retention of both resiquimod and the electrostatically adsorbed TB subunit antigen Ag85B-ESAT6-Rv2660c (H56). Terbium 180-182 toll like receptor 7 Homo sapiens 13-17 30047605-1 2018 AIMS: The aim of this study is to evaluate the potential association between N-acetyltransferase type 2 (NAT2) polymorphisms and drug-induced liver injury during anti-TB treatment (AT-DILI). Terbium 167-169 N-acetyltransferase 2 Homo sapiens 105-109 30265593-2 2018 In Thoroughbreds (TB), we previously demonstrated that the haplotype association for height (LCORL/NCAPG locus on ECA3, which affects body size) and RLN was coincident. Terbium 18-20 ligand dependent nuclear receptor corepressor like Equus caballus 93-98 29745810-6 2018 RESULTS: The best results were found for the CTR and RAL20 groups, in which the BV, BV/TV, Tb.Sp, and Tb.N parameters were statistically significant in comparison with RAL10 (p < 0.05). Terbium 91-93 calcitonin receptor Rattus norvegicus 45-48 29745810-6 2018 RESULTS: The best results were found for the CTR and RAL20 groups, in which the BV, BV/TV, Tb.Sp, and Tb.N parameters were statistically significant in comparison with RAL10 (p < 0.05). Terbium 102-104 calcitonin receptor Rattus norvegicus 45-48 30864749-0 2018 New TB Tools Need to be Affordable in the Private Sector: The Case Study of Xpert MTB/RIF. Terbium 4-6 ras homolog family member F, filopodia associated Homo sapiens 86-89 30509649-5 2018 At 27 C, in the E2(+) and E2(-) groups, the Tb and Ttail were greater in rats applied menthol than that in rats applied vehicle. Terbium 45-47 dihydrolipoamide S-succinyltransferase Rattus norvegicus 17-19 30509649-6 2018 In rats applied menthol, the Tb in the E2(+) group was lower than that in the E2(-) group. Terbium 29-31 dihydrolipoamide S-succinyltransferase Rattus norvegicus 39-41 30509649-9 2018 E2 administration suppresses Tb elevation induced by application of menthol to ovariectomized rats. Terbium 29-31 dihydrolipoamide S-succinyltransferase Rattus norvegicus 0-2 30265593-2 2018 In Thoroughbreds (TB), we previously demonstrated that the haplotype association for height (LCORL/NCAPG locus on ECA3, which affects body size) and RLN was coincident. Terbium 18-20 non-SMC condensin I complex subunit G Equus caballus 99-104 30215692-8 2018 They were more likely to advise patients not to travel to TB-endemic area if on both anti-tumour necrosis factor [TNF] and azathioprine, than if on vedolizumab and azathioprine [47% vs 17.6%, p < 0.01]. Terbium 58-60 tumor necrosis factor Homo sapiens 114-117 30514502-2 2018 In this study, we identified a CD1c DC subset with phenotype of CD1c+CD11c+CD19-CD11b+ that was significantly increased in tuberculous pleural effusions and in peripheral blood from patients with TB compared with that from healthy controls (p < 0.0001). Terbium 196-198 CD1c molecule Homo sapiens 31-35 30514502-2 2018 In this study, we identified a CD1c DC subset with phenotype of CD1c+CD11c+CD19-CD11b+ that was significantly increased in tuberculous pleural effusions and in peripheral blood from patients with TB compared with that from healthy controls (p < 0.0001). Terbium 196-198 CD1c molecule Homo sapiens 64-68 30514502-2 2018 In this study, we identified a CD1c DC subset with phenotype of CD1c+CD11c+CD19-CD11b+ that was significantly increased in tuberculous pleural effusions and in peripheral blood from patients with TB compared with that from healthy controls (p < 0.0001). Terbium 196-198 integrin subunit alpha X Homo sapiens 69-74 30514502-2 2018 In this study, we identified a CD1c DC subset with phenotype of CD1c+CD11c+CD19-CD11b+ that was significantly increased in tuberculous pleural effusions and in peripheral blood from patients with TB compared with that from healthy controls (p < 0.0001). Terbium 196-198 CD19 molecule Homo sapiens 75-79 30514502-2 2018 In this study, we identified a CD1c DC subset with phenotype of CD1c+CD11c+CD19-CD11b+ that was significantly increased in tuberculous pleural effusions and in peripheral blood from patients with TB compared with that from healthy controls (p < 0.0001). Terbium 196-198 integrin subunit alpha M Homo sapiens 80-85 30514502-4 2018 After effective anti-TB chemotherapy, the frequency of CD1c+CD11b+ DC subset in peripheral blood and tuberculous pleural effusions was decreased. Terbium 21-23 CD1c molecule Homo sapiens 55-59 30514502-4 2018 After effective anti-TB chemotherapy, the frequency of CD1c+CD11b+ DC subset in peripheral blood and tuberculous pleural effusions was decreased. Terbium 21-23 integrin subunit alpha M Homo sapiens 60-65 30052856-10 2018 One case of active TB [isoniazid-resistant strain] occurred in a patient with positive baseline TST receiving anti-TNF [0.05 events/100 patient-years]. Terbium 19-21 tumor necrosis factor Homo sapiens 115-118 32254721-6 2018 Such a Tb-GMP-Eu CPNs sensor exhibited sensitive response to ALP with a detection limit down to 0.004 U L-1. Terbium 7-9 alkaline phosphatase, placental Homo sapiens 61-64 29777718-5 2018 Similarly, LTBI with LBMI is also characterized by diminished TB-antigen stimulated levels of CCL1, CCL2, CCL3, CCL4, CCL11, CXCL1, CXCL2, CXCL9, CXCL10 and CXCL11. Terbium 12-14 C-C motif chemokine ligand 1 Homo sapiens 94-98 29777718-5 2018 Similarly, LTBI with LBMI is also characterized by diminished TB-antigen stimulated levels of CCL1, CCL2, CCL3, CCL4, CCL11, CXCL1, CXCL2, CXCL9, CXCL10 and CXCL11. Terbium 12-14 C-C motif chemokine ligand 2 Homo sapiens 100-104 29777718-5 2018 Similarly, LTBI with LBMI is also characterized by diminished TB-antigen stimulated levels of CCL1, CCL2, CCL3, CCL4, CCL11, CXCL1, CXCL2, CXCL9, CXCL10 and CXCL11. Terbium 12-14 C-C motif chemokine ligand 3 Homo sapiens 106-110 29777718-5 2018 Similarly, LTBI with LBMI is also characterized by diminished TB-antigen stimulated levels of CCL1, CCL2, CCL3, CCL4, CCL11, CXCL1, CXCL2, CXCL9, CXCL10 and CXCL11. Terbium 12-14 C-C motif chemokine ligand 4 Homo sapiens 112-116 29777718-5 2018 Similarly, LTBI with LBMI is also characterized by diminished TB-antigen stimulated levels of CCL1, CCL2, CCL3, CCL4, CCL11, CXCL1, CXCL2, CXCL9, CXCL10 and CXCL11. Terbium 12-14 C-C motif chemokine ligand 11 Homo sapiens 118-123 29777718-5 2018 Similarly, LTBI with LBMI is also characterized by diminished TB-antigen stimulated levels of CCL1, CCL2, CCL3, CCL4, CCL11, CXCL1, CXCL2, CXCL9, CXCL10 and CXCL11. Terbium 12-14 C-X-C motif chemokine ligand 1 Homo sapiens 125-130 29777718-5 2018 Similarly, LTBI with LBMI is also characterized by diminished TB-antigen stimulated levels of CCL1, CCL2, CCL3, CCL4, CCL11, CXCL1, CXCL2, CXCL9, CXCL10 and CXCL11. Terbium 12-14 C-X-C motif chemokine ligand 2 Homo sapiens 132-137 29777718-5 2018 Similarly, LTBI with LBMI is also characterized by diminished TB-antigen stimulated levels of CCL1, CCL2, CCL3, CCL4, CCL11, CXCL1, CXCL2, CXCL9, CXCL10 and CXCL11. Terbium 12-14 C-X-C motif chemokine ligand 9 Homo sapiens 139-144 29777718-5 2018 Similarly, LTBI with LBMI is also characterized by diminished TB-antigen stimulated levels of CCL1, CCL2, CCL3, CCL4, CCL11, CXCL1, CXCL2, CXCL9, CXCL10 and CXCL11. Terbium 12-14 C-X-C motif chemokine ligand 10 Homo sapiens 146-152 29777718-5 2018 Similarly, LTBI with LBMI is also characterized by diminished TB-antigen stimulated levels of CCL1, CCL2, CCL3, CCL4, CCL11, CXCL1, CXCL2, CXCL9, CXCL10 and CXCL11. Terbium 12-14 C-X-C motif chemokine ligand 11 Homo sapiens 157-163 30420888-11 2018 Therefore, we suggest that the criterion of a TST reaction of 5 mm to define latent TB infection in our population should be reevaluated. Terbium 84-86 thiosulfate sulfurtransferase Homo sapiens 46-49 32254721-0 2018 Fluorescence assay for alkaline phosphatase activity based on energy transfer from terbium to europium in lanthanide coordination polymer nanoparticles. Terbium 83-90 alkaline phosphatase, placental Homo sapiens 23-43 32254721-1 2018 In this study, bimetallic lanthanide coordination polymer nanoparticles (Tb-GMP-Eu CPNs) were developed for sensing alkaline phosphatase (ALP) by utilizing guanine monophosphate (GMP) as the bridge ligand to self-assemble with Tb3+ and Eu3+ in Tris-HCl buffer solution. Terbium 73-75 alkaline phosphatase, placental Homo sapiens 116-136 32254721-1 2018 In this study, bimetallic lanthanide coordination polymer nanoparticles (Tb-GMP-Eu CPNs) were developed for sensing alkaline phosphatase (ALP) by utilizing guanine monophosphate (GMP) as the bridge ligand to self-assemble with Tb3+ and Eu3+ in Tris-HCl buffer solution. Terbium 73-75 alkaline phosphatase, placental Homo sapiens 138-141 32254721-4 2018 When ALP was introduced into the Tb-GMP-Eu CPNs system, it would destruct the combination between Tb and GMP by a dephosphorylation process, resulting in interruption of energy transfer from Tb3+ to Eu3+ and therefore the fluorescence quenching of Eu3+. Terbium 33-35 alkaline phosphatase, placental Homo sapiens 5-8 32254721-4 2018 When ALP was introduced into the Tb-GMP-Eu CPNs system, it would destruct the combination between Tb and GMP by a dephosphorylation process, resulting in interruption of energy transfer from Tb3+ to Eu3+ and therefore the fluorescence quenching of Eu3+. Terbium 98-100 alkaline phosphatase, placental Homo sapiens 5-8 30351077-2 2018 The general reaction between CuCl2 2H2O, LnCl3 6H2O, phenoxH, and NEt3 in a 1:2:2:4 molar ratio, in a solvent mixture comprising MeCN and MeOH, afforded brown crystals of a new family of [Cu3LnCl3(phenox)6(MeOH)3] clusters (Ln = Gd (1), Tb (2), Dy (3)) that possess an unprecedented [Cu3Ln(mu-NO)6]3+ "propeller"-like core. Terbium 237-239 tetraspanin 2 Homo sapiens 66-70 30180300-13 2018 CONCLUSION: Peripheral and respiratory muscle strength and leptin levels were reduced in patients with active TB. Terbium 110-112 leptin Homo sapiens 59-65 30379230-8 2018 BFP participation (OR=0.5; 95% CI 0.3-0.6) and BCG vaccination (OR=0.5; 95% CI 0.3-0.9) were found to be protective factors against TB. Terbium 132-134 ring finger protein 112 Homo sapiens 0-3 30333506-0 2018 Age-related waning of immune responses to BCG in healthy children supports the need for a booster dose of BCG in TB endemic countries. Terbium 113-115 renin binding protein Homo sapiens 0-3 30265522-0 2018 Frustration and Glasslike Character in RIn1- xMn xO3 (R = Tb, Dy, Gd). Terbium 58-60 Ras and Rab interactor 1 Homo sapiens 39-43 30406140-7 2018 Micro-CT analyses showed that (1) 99Tc-MDP reversed glucocorticoid induced bone microarchitecture destruction by increasing BV/TV, Tb.Th, and Tb.N and decreasing BS/BV, Tb.Sp, and TBPf; (2) effect of 99Tc-MDP increased as its dosage increased; and (3) 99Tc-MDP could improve cortical bone thickness while MDP failed to do so. Terbium 131-133 dipeptidase 1 Homo sapiens 39-42 30406140-7 2018 Micro-CT analyses showed that (1) 99Tc-MDP reversed glucocorticoid induced bone microarchitecture destruction by increasing BV/TV, Tb.Th, and Tb.N and decreasing BS/BV, Tb.Sp, and TBPf; (2) effect of 99Tc-MDP increased as its dosage increased; and (3) 99Tc-MDP could improve cortical bone thickness while MDP failed to do so. Terbium 142-144 dipeptidase 1 Homo sapiens 39-42 30393476-9 2018 Conclusions: The MBL2 rs1800451 polymorphism is associated with decreased TB risk in the general population, and A/O, rs7096206, rs1800450 and rs1800451 are likely to be associated with the risk for some specific ethnic groups. Terbium 74-76 mannose binding lectin 2 Homo sapiens 17-21 30285633-1 2018 BACKGROUND: The depletion of CD4 cell is the underlying reason for TB hyper-susceptibility among people with HIV. Terbium 67-69 CD4 molecule Homo sapiens 29-32 30148839-4 2018 This study aims to evaluate the use either isolated or in combination with adenosine deaminase (ADA), interferon-gamma (IFN-gamma), interferon-gamma inducible protein of 10-kD (IP-10) levels on PF in order to guide an accurate anti-TB treatment in microbiologically non-confirmed cases. Terbium 232-234 C-X-C motif chemokine ligand 10 Homo sapiens 177-182 30011241-5 2018 The dual-wavelength emission property of terbium-conjugated anti-BTK antibody served as the energy donor for two fluorescent energy acceptors with distinct excitation and emission spectra. Terbium 41-48 Bruton tyrosine kinase Homo sapiens 65-68 29993186-7 2018 The cellular data confirmed that TB-triggered DNA damage and induced apoptosis of U2OS cells by regulation of Mki67, PARP, caspase 3 and H2AX, and Western blot assay showed an activation of p53 signalling pathway. Terbium 33-35 marker of proliferation Ki-67 Homo sapiens 110-115 29993186-7 2018 The cellular data confirmed that TB-triggered DNA damage and induced apoptosis of U2OS cells by regulation of Mki67, PARP, caspase 3 and H2AX, and Western blot assay showed an activation of p53 signalling pathway. Terbium 33-35 collagen type XI alpha 2 chain Homo sapiens 117-121 29993186-7 2018 The cellular data confirmed that TB-triggered DNA damage and induced apoptosis of U2OS cells by regulation of Mki67, PARP, caspase 3 and H2AX, and Western blot assay showed an activation of p53 signalling pathway. Terbium 33-35 caspase 3 Homo sapiens 123-132 29993186-7 2018 The cellular data confirmed that TB-triggered DNA damage and induced apoptosis of U2OS cells by regulation of Mki67, PARP, caspase 3 and H2AX, and Western blot assay showed an activation of p53 signalling pathway. Terbium 33-35 H2A.X variant histone Homo sapiens 137-141 29704228-9 2018 After 24 months, the area under the curve (AUC) of GLP1 increased and in the SG + TB group and the AUC of the GIP concentrations was lower in the SG + TB group than in the SMT. Terbium 151-153 gastric inhibitory polypeptide Homo sapiens 110-113 29704228-10 2018 At 3 months, SG + TB group showed a marked increase in FGF19 levels (74.1 +- 45.8 to 237.3 +- 234 pg/mL; P = 0.001). Terbium 18-20 fibroblast growth factor 19 Homo sapiens 55-60 30323818-6 2018 At 9 weeks after anti-TB treatment initiation the frequencies of activation marker (CD38, HLA-DR, Ki67) positive MTB-specific, but not total CD4 T cells, were significantly reduced (p < 0.0001). Terbium 22-24 CD38 molecule Homo sapiens 84-88 30005014-2 2018 Clinical trials have reported early (within 2 weeks of TB therapy) antiretroviral therapy (ART) reduces mortality among HIV-TB co-infected research participants with low CD4 cell counts, but this has not been consistently observed. Terbium 55-57 CD4 molecule Homo sapiens 170-173 30245860-3 2018 Data were previously collected on IFN-gamma secreting CD4+ T cells over time for novel TB vaccines H56 and H1 adjuvanted with IC31 in mice (1 dose groups (0.1-1.5 and 15 mug H56 + IC31), 45 mice) and humans (1 dose (50 mug H56/H1 + IC31), 18 humans). Terbium 87-89 interferon gamma Mus musculus 34-43 30208925-14 2018 There was an interaction between CYP27A1 methylation level and 1,25-dihydroxyvitamin D concentration associated with the risk of TB (ORinteraction = 4.11, 95% CI 1.26-13.36, P = 0.019). Terbium 129-131 cytochrome P450 family 27 subfamily A member 1 Homo sapiens 33-40 30130101-4 2018 The TbIII derivative, Tb-TEMPO-CN, also shows strong Tb-radical AF coupling, which has been rationalized using the ab initio CASSCF approach ( JTb-rad = -23.02 K, -16.7 cm-1) and confirmed by luminescence measurements. Terbium 4-6 jumping translocation breakpoint Homo sapiens 143-146 30130101-4 2018 The TbIII derivative, Tb-TEMPO-CN, also shows strong Tb-radical AF coupling, which has been rationalized using the ab initio CASSCF approach ( JTb-rad = -23.02 K, -16.7 cm-1) and confirmed by luminescence measurements. Terbium 22-24 jumping translocation breakpoint Homo sapiens 143-146 29961269-10 2018 By further validation, hsa_circRNA_103571 exhibited significant decrease in active TB patients and showed potential interaction with active TB-related miRNAs such as miR-29a and miR-16. Terbium 83-85 microRNA 29a Homo sapiens 166-173 29961269-10 2018 By further validation, hsa_circRNA_103571 exhibited significant decrease in active TB patients and showed potential interaction with active TB-related miRNAs such as miR-29a and miR-16. Terbium 83-85 glycerophosphodiester phosphodiesterase 1 Homo sapiens 178-184 29961269-10 2018 By further validation, hsa_circRNA_103571 exhibited significant decrease in active TB patients and showed potential interaction with active TB-related miRNAs such as miR-29a and miR-16. Terbium 140-142 microRNA 29a Homo sapiens 166-173 29961269-10 2018 By further validation, hsa_circRNA_103571 exhibited significant decrease in active TB patients and showed potential interaction with active TB-related miRNAs such as miR-29a and miR-16. Terbium 140-142 glycerophosphodiester phosphodiesterase 1 Homo sapiens 178-184 30025786-5 2018 RESULTS: While IP-10 levels were significantly reduced in TB+ subjects in all the sub-groups, IL-8 levels were significantly reduced in NDM-TB+ and increased in KDM-TB+ subjects. Terbium 58-61 C-X-C motif chemokine ligand 10 Homo sapiens 15-20 30025786-5 2018 RESULTS: While IP-10 levels were significantly reduced in TB+ subjects in all the sub-groups, IL-8 levels were significantly reduced in NDM-TB+ and increased in KDM-TB+ subjects. Terbium 58-60 C-X-C motif chemokine ligand 10 Homo sapiens 15-20 30025786-5 2018 RESULTS: While IP-10 levels were significantly reduced in TB+ subjects in all the sub-groups, IL-8 levels were significantly reduced in NDM-TB+ and increased in KDM-TB+ subjects. Terbium 140-142 C-X-C motif chemokine ligand 8 Homo sapiens 94-98 30025786-6 2018 SDF-1 levels were significantly elevated in TB+ subjects in all the subgroups, except for KDM-TB+. Terbium 44-47 C-X-C motif chemokine ligand 12 Homo sapiens 0-5 30157233-7 2018 RESULTS: We found that the addition of IL-7 led to significantly higher release of IFN-gamma in individuals with active TB from 4.2IU/ml (IQR 1.4-6.9IU/ml) to 5.1IU/ml (IQR 1.5-8.1IU/ml, p = 0.0057), and we found an indication of a lower release of both IFN-gamma and IP-10 in participants with negative tests. Terbium 120-122 interferon gamma Homo sapiens 83-92 29847333-8 2018 In another cohort of 749 patients presenting with at least one TB-related symptom and clinically evaluated, CRP had a sensitivity of 98.7% and specificity of 48.3%. Terbium 63-65 C-reactive protein Homo sapiens 108-111 29847333-10 2018 Use of CRP as a screening tool to exclude active TB could identify the same number of HIV-associated TB cases, but reduce the use of diagnostic sputum testing in TB-endemic regions. Terbium 49-51 C-reactive protein Homo sapiens 7-10 30148839-18 2018 The combination of IFN-gamma and ADA, in a reviewed cut-off point, showed to be particularly useful to clinicians as their positive results combined prompts immediate treatment for TB while both negative results suggest further investigation. Terbium 181-183 interferon gamma Homo sapiens 19-28 30148839-18 2018 The combination of IFN-gamma and ADA, in a reviewed cut-off point, showed to be particularly useful to clinicians as their positive results combined prompts immediate treatment for TB while both negative results suggest further investigation. Terbium 181-183 adenosine deaminase Homo sapiens 33-36 30079524-5 2018 Immediate applicability by the quantification of the human epidermal growth factor receptor 2 (HER2) in serum-containing samples using time-gated Tb-to-QD FRET detection on the clinical benchtop immunoassay analyzer KRYPTOR is demonstrated here. Terbium 146-148 erb-b2 receptor tyrosine kinase 2 Homo sapiens 59-93 29684756-1 2018 Although IL-10 is known to be an important cytokine in the immune response to TB, very little is known about the role of IL-20 subfamily of cytokines in the host response to TB. Terbium 78-80 interleukin 10 Homo sapiens 9-14 29345081-12 2018 Therefore, this method for the screening of LTBI in Indian patients with RA being considered for tumor necrosis factor alpha treatment could be satisfactory for offsetting TB flare. Terbium 45-47 tumor necrosis factor Homo sapiens 97-124 29901122-12 2018 ORM2, S100A9, IL-36alpha and SOD1 were associated with the development of TB, and have the potential to distinguish between different stages of TB. Terbium 74-76 orosomucoid 2 Homo sapiens 0-4 29901122-12 2018 ORM2, S100A9, IL-36alpha and SOD1 were associated with the development of TB, and have the potential to distinguish between different stages of TB. Terbium 74-76 S100 calcium binding protein A9 Homo sapiens 6-12 29901122-12 2018 ORM2, S100A9, IL-36alpha and SOD1 were associated with the development of TB, and have the potential to distinguish between different stages of TB. Terbium 74-76 interleukin 36 alpha Homo sapiens 14-24 29901122-12 2018 ORM2, S100A9, IL-36alpha and SOD1 were associated with the development of TB, and have the potential to distinguish between different stages of TB. Terbium 74-76 superoxide dismutase 1 Homo sapiens 29-33 29901122-12 2018 ORM2, S100A9, IL-36alpha and SOD1 were associated with the development of TB, and have the potential to distinguish between different stages of TB. Terbium 144-146 orosomucoid 2 Homo sapiens 0-4 29901122-12 2018 ORM2, S100A9, IL-36alpha and SOD1 were associated with the development of TB, and have the potential to distinguish between different stages of TB. Terbium 144-146 interleukin 36 alpha Homo sapiens 14-24 29901122-12 2018 ORM2, S100A9, IL-36alpha and SOD1 were associated with the development of TB, and have the potential to distinguish between different stages of TB. Terbium 144-146 superoxide dismutase 1 Homo sapiens 29-33 30079524-5 2018 Immediate applicability by the quantification of the human epidermal growth factor receptor 2 (HER2) in serum-containing samples using time-gated Tb-to-QD FRET detection on the clinical benchtop immunoassay analyzer KRYPTOR is demonstrated here. Terbium 146-148 erb-b2 receptor tyrosine kinase 2 Homo sapiens 95-99 30064368-12 2018 In 2013, over 75% of ART-naive TB patients still had a CD4 count < 350 cells/mm3. Terbium 31-33 CD4 molecule Homo sapiens 55-58 30064368-14 2018 In multivariate analysis a decrease in TB mortality was most strongly associated with CD4 count (Adjusted HR 0.82 per increase of 50 cells/mm3, 95% CI: 0.81-0.83, p < 001) and the initiation of ART during TB treatment (Adjusted HR 0.39, 95% CI: 0.35-0.42, p < 0.001). Terbium 39-41 CD4 molecule Homo sapiens 86-89 30064368-14 2018 In multivariate analysis a decrease in TB mortality was most strongly associated with CD4 count (Adjusted HR 0.82 per increase of 50 cells/mm3, 95% CI: 0.81-0.83, p < 001) and the initiation of ART during TB treatment (Adjusted HR 0.39, 95% CI: 0.35-0.42, p < 0.001). Terbium 208-210 CD4 molecule Homo sapiens 86-89 30064368-16 2018 However TB still remained a major presenting opportunistic infection with the majority of cases occurring at low CD4 counts. Terbium 8-10 CD4 molecule Homo sapiens 113-116 30045341-11 2018 VDR genotypes may be associated with TB clinical characteristics. Terbium 37-39 vitamin D receptor Homo sapiens 0-3 30011931-0 2018 Effect of Tb-doped Concentration Variation on the Electrical and Dielectric Properties of CaF2 Nanoparticles. Terbium 10-12 CCR4-NOT transcription complex subunit 8 Homo sapiens 90-94 30073038-9 2018 A total of 43 (11.0%) participants developed TB while receiving ART which was independently associated with male gender (OR = 2.9; p=0.007), WHO clinical stage 3 and 4 (OR = 1.4; p=0.029), baseline CD4 count <200 cells/microl (OR = 9.1; p < 0.001), and having not used IPT (OR = 3.1; p=0.05). Terbium 45-47 CD4 molecule Homo sapiens 198-201 29870777-8 2018 FKN induced a long lasting febrile response in which the highest dose (500 pg/muL) induced a marked rise on Tb that was accompanied by a reduced Tsk and HLI, consequently. Terbium 108-110 C-X3-C motif chemokine ligand 1 Rattus norvegicus 0-3 30157233-7 2018 RESULTS: We found that the addition of IL-7 led to significantly higher release of IFN-gamma in individuals with active TB from 4.2IU/ml (IQR 1.4-6.9IU/ml) to 5.1IU/ml (IQR 1.5-8.1IU/ml, p = 0.0057), and we found an indication of a lower release of both IFN-gamma and IP-10 in participants with negative tests. Terbium 120-122 interleukin 7 Homo sapiens 39-43 29743310-5 2018 Additionally, we document a high degree of correlation between IFN-gamma levels in the QFT-GIT TB antigen tube and each of the two QFT-Plus TB antigen tubes, as well as between the QFT-Plus TB1 and TB2 tubes (Pearson"s correlation coefficients [R] > 0.95). Terbium 95-97 interferon gamma Homo sapiens 63-72 29743310-5 2018 Additionally, we document a high degree of correlation between IFN-gamma levels in the QFT-GIT TB antigen tube and each of the two QFT-Plus TB antigen tubes, as well as between the QFT-Plus TB1 and TB2 tubes (Pearson"s correlation coefficients [R] > 0.95). Terbium 140-142 interferon gamma Homo sapiens 63-72 29914244-3 2018 Twenty-one percent (n = 14) of the patients with TB coinfection died during the study period and these patients had significantly lower baseline CD4 counts at the time of TB diagnosis (P = 0.005). Terbium 49-51 CD4 molecule Homo sapiens 145-148 29914244-4 2018 None of the patients with CD4 count of >=200 cells/mm3 died during follow-up and a low CD4 count at the time of TB diagnosis (<200 cells/ mm3) was associated with poor survival (P = 0.012). Terbium 115-117 CD4 molecule Homo sapiens 90-93 29870777-10 2018 Our data consistently indicate that FKN increases AVPO PGE2 production and Tb, accompanied by raised plasma IL-6 levels and activation of the hypothalamus-pituitary-adrenal axis. Terbium 75-77 C-X3-C motif chemokine ligand 1 Rattus norvegicus 36-39 29486365-2 2018 We tried to verified the hypothesis that TLR2 genetic loci effect on the susceptibility to TB in the Western Chinese population. Terbium 91-93 toll like receptor 2 Homo sapiens 41-45 29486365-12 2018 Our study proposed that common TLR2 genetic variants may influence TB development and disease phenotypes in Western Chinese population. Terbium 67-69 toll like receptor 2 Homo sapiens 31-35 29843631-4 2018 METHODS: IP-10 was measured using enzyme-linked immunosorbent assays in urine and serum samples collected concomitantly from 23 patients with active TB and 21 healthy adults (44 total individuals). Terbium 149-151 C-X-C motif chemokine ligand 10 Homo sapiens 9-14 29843631-8 2018 CONCLUSIONS: Unstimulated IP-10 in urine can be used as a biomarker to monitor treatment response in patients with active pulmonary TB. Terbium 132-134 C-X-C motif chemokine ligand 10 Homo sapiens 26-31 29758082-2 2018 We evaluated whether adjunctive inhibition of MMP-9 could improve the response to standard TB treatment in a mouse model that develops necrotic lesions. Terbium 91-93 matrix metallopeptidase 9 Mus musculus 46-51 31458775-7 2018 Interestingly, the luminescence color of breathing co-doped lanthanide MOF 1"-Eu0.015Tb0.985 is blue-shifted and turned from orange to green with an increase in temperature, which can be attributed to a change in the relative intensity of Tb and Eu emissions, and is quite different from that observed for the reported related compounds. Terbium 85-87 lysine acetyltransferase 8 Homo sapiens 71-74 29477867-6 2018 We found that neutrophil-associated miR-197-3p, miR-99b-5p and miR-191-5p transcript levels were significantly lower in TB cases. Terbium 120-122 microRNA 1973 Homo sapiens 36-46 29477867-6 2018 We found that neutrophil-associated miR-197-3p, miR-99b-5p and miR-191-5p transcript levels were significantly lower in TB cases. Terbium 120-122 microRNA 1915 Homo sapiens 63-73 29477867-7 2018 Additionally, B-cell-associated miR-320a, miR-204-5p, miR331-3p and other transcript levels were higher in TB cases. Terbium 107-109 microRNA 320a Homo sapiens 32-40 29477867-7 2018 Additionally, B-cell-associated miR-320a, miR-204-5p, miR331-3p and other transcript levels were higher in TB cases. Terbium 107-109 microRNA 331 Homo sapiens 54-60 29768503-14 2018 Gaps remain in getting patients with CD4<50/muL to receive ART within the recommended two weeks post TB treatment initiation. Terbium 104-106 CD4 molecule Homo sapiens 37-40 29758082-6 2018 Compared to the standard TB treatment, relapse rates in animals that received adjunctive treatments with anti-MMP-9 antibody or etanercept were significantly decreased to 25.9% (P = 0.006) and 29.8% (P = 0.019) respectively, but were not different from the arm that received the isotype control antibody (25.9%). Terbium 25-27 matrix metallopeptidase 9 Mus musculus 110-115 29740708-0 2018 Fluorometric determination of the activity of alkaline phosphatase based on the competitive binding of gold nanoparticles and pyrophosphate to CePO4:Tb nanorods. Terbium 149-151 alkaline phosphatase, placental Homo sapiens 46-66 29740708-4 2018 In the presence of ALP, PPi is hydrolyzed to form phosphate which has much weaker affinity for the CePO4:Tb. Terbium 105-107 alkaline phosphatase, placental Homo sapiens 19-22 29740708-10 2018 Graphical abstract A assay for the detection of alkaline phosphatase is proposed based on the fluorescence resonance energy transfer between CePO4:Tb and AuNPs. Terbium 147-149 alkaline phosphatase, placental Homo sapiens 48-68 29475111-17 2018 Combination of PTH and GH increased distal femoral metaphyseal bone strength (+45%, p<0.001), BV/TV (+50%, p<0.05), Tb.Th (+40%, p<0.05), and whole femoral aBMD (+15%, p<0.001) compared to BTX and muscle mass (+21%, p<0.05) compared to BTX+PTH. Terbium 122-124 gonadotropin releasing hormone receptor Rattus norvegicus 23-25 29866214-5 2018 RESULTS: Nine patients with active Tb-SLC (14 eyes) and 8 with active SC (12 eyes) were included. Terbium 35-37 C-C motif chemokine ligand 21 Homo sapiens 38-41 29866214-7 2018 A hyporeflective, wedge-shaped band was observed more often in the SC group [5 Tb-SLC eyes (36%), 9 SC eyes (75%); P = 0.045] than in the Tb-SLC group. Terbium 79-81 C-C motif chemokine ligand 21 Homo sapiens 82-85 29866214-7 2018 A hyporeflective, wedge-shaped band was observed more often in the SC group [5 Tb-SLC eyes (36%), 9 SC eyes (75%); P = 0.045] than in the Tb-SLC group. Terbium 138-140 C-C motif chemokine ligand 21 Homo sapiens 141-144 29421751-3 2018 Similar to 5alpha-dihydrotestosterone (DHT), 17 TB was reported to exhibit endocrine disrupting effects on animals and humans due to its androgenic effect via binding to the androgen receptor. Terbium 48-50 androgen receptor Homo sapiens 174-191 29421751-6 2018 Treatment with 17 TB increased the expression of cell cycle regulatory proteins, cyclin D2/CDK-4 and cyclin E/CDK-2, whereas the expression of p27 was down-regulated. Terbium 18-20 cyclin D2 Homo sapiens 81-90 29421751-6 2018 Treatment with 17 TB increased the expression of cell cycle regulatory proteins, cyclin D2/CDK-4 and cyclin E/CDK-2, whereas the expression of p27 was down-regulated. Terbium 18-20 cyclin dependent kinase 4 Homo sapiens 91-96 29421751-6 2018 Treatment with 17 TB increased the expression of cell cycle regulatory proteins, cyclin D2/CDK-4 and cyclin E/CDK-2, whereas the expression of p27 was down-regulated. Terbium 18-20 cyclin dependent kinase 2 Homo sapiens 110-115 29421751-6 2018 Treatment with 17 TB increased the expression of cell cycle regulatory proteins, cyclin D2/CDK-4 and cyclin E/CDK-2, whereas the expression of p27 was down-regulated. Terbium 18-20 dynactin subunit 6 Homo sapiens 143-146 29421751-8 2018 When 22Rv1 cells were exposed to 30 pM of 17 TB, which is the effective concentration (EC50) value required to observe proliferative effects on 22Rv1 cells, the expression levels of the phosphorylated forms of Akt and GSK3beta were increased. Terbium 45-47 AKT serine/threonine kinase 1 Homo sapiens 210-213 29421751-8 2018 When 22Rv1 cells were exposed to 30 pM of 17 TB, which is the effective concentration (EC50) value required to observe proliferative effects on 22Rv1 cells, the expression levels of the phosphorylated forms of Akt and GSK3beta were increased. Terbium 45-47 glycogen synthase kinase 3 beta Homo sapiens 218-226 29421751-9 2018 This study demonstrates that 17 TB induces AR-dependent proliferation through the modulation of cell cycle-related proteins in the Akt signaling pathway. Terbium 32-34 AKT serine/threonine kinase 1 Homo sapiens 131-134 29526607-3 2018 DESIGN: This prospective, cross-sectional study used interferon-gamma release assay (IGRA) to screen for TB among Emirati citizens between August-2016 and May-2017; expatriates were not included in this study. Terbium 105-107 interferon gamma Homo sapiens 53-69 29779769-1 2018 This study aimed to determine whether there are seasonal changes in the performance of QuantiFERON-TB Gold In-Tube (QFT-GIT) assays, an interferon-gamma release assay widely used for the diagnosis of tuberculosis infection. Terbium 99-101 interferon gamma Homo sapiens 136-152 29617458-10 2018 Considering their lower capacity to produce TB-specific interferon-gamma, a lower cut-off level for defining QFT-Plus-positivity may be considered in HIV-positive pregnant women. Terbium 44-46 interferon gamma Homo sapiens 56-72 32254437-2 2018 We now report the detection and assay of two biologically important enzymes, alkaline phosphatase and beta-galactosidase, in Eu- or Tb-based cholate hydrogels, respectively, and on filter paper discs coated with such hydrogels. Terbium 132-134 galactosidase beta 1 Homo sapiens 102-120 29622693-0 2018 Stratification by interferon-gamma release assay level predicts risk of incident TB. Terbium 81-83 interferon gamma Homo sapiens 18-34 29622693-5 2018 We used restricted cubic splines to model non-linear relationships between IFN-gamma levels and TB, and applied these findings to a competing risk model. Terbium 96-98 interferon gamma Homo sapiens 75-84 29622693-8 2018 TB risk increased with the IFN-gamma level until a plateau level, above which further increase was not associated with additional prognostic information. Terbium 0-2 interferon gamma Homo sapiens 27-36 29622693-9 2018 The HRs for TB were 8.8 (95% CI 4.7 to 16.5), 19.2 (95% CI 11.6 to 31.6) and 31.3 (95% CI 19.8 to 49.5) times higher with IFN-gamma levels of 0.35 to <1.00, 1.00 to <4.00 and >4.00 IU/mL, respectively, compared with negative tests (<0.35 IU/mL). Terbium 12-14 interferon gamma Homo sapiens 122-131 29140933-1 2018 BACKGROUND: The T-SPOT.TB, an interferon-gamma release assay, is an indirect test of Mycobacterium tuberculosis infection. Terbium 23-25 interferon gamma Homo sapiens 30-46 29174965-5 2018 The Rv0183-specific IL-6 response was significantly higher in aTB patients (n = 128) than in those with non-TB lung disease (n = 64) and in healthy individuals (n = 327) (p < 0.0001), and not affected by latent TB infection. Terbium 63-65 interleukin 6 Homo sapiens 20-24 29174965-8 2018 CONCLUSIONS: These results clearly show that the Rv0183 antigen-specific IL-6 response has the potential to be used as an immune-diagnosis test for active TB in clinical practice. Terbium 155-157 interleukin 6 Homo sapiens 73-77 29388301-6 2018 Moreover, the two scaffolds have differential inhibitory activities against the two homologous Ndh-2 enzymes in Mtb, which will allow precise control over Ndh-2 function in Mtb to facilitate the assessment of this anti-TB drug target. Terbium 219-221 DExH-box helicase 9 Homo sapiens 95-100 29558947-6 2018 TB was scored across 10 high power fields at the invasive front in cytokeratin AE1/AE3 stained sections. Terbium 0-2 solute carrier family 4 member 1 (Diego blood group) Homo sapiens 79-82 29558947-6 2018 TB was scored across 10 high power fields at the invasive front in cytokeratin AE1/AE3 stained sections. Terbium 0-2 solute carrier family 4 member 3 Homo sapiens 83-86 29548281-4 2018 We recently showed that assays of M.tb thymidylate kinase (TMKmt) antigen and host specific IgG can differentiate ATB from LTBI and or no TB (NTB, or healthy controls). Terbium 115-117 deoxythymidylate kinase Homo sapiens 39-57 29499060-2 2018 We aimed to determine the effect of two new potential interventions for TB contact tracing programmes: Point of Care CD4 (PoC CD4) on HIV linkage to care and household Isoniazid Preventive Therapy (IPT) provision on uptake and retention of IPT. Terbium 72-74 CD4 molecule Homo sapiens 126-129