PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 12390813-2 2002 METHODS: Rat primary hepatocytes with IR induced by high concentration of human insulin were used in which the incorporation rates of 14C-2-deoxyglucose and 14C-acetate were determined to estimate the insulin sensitivity of the cells and IDE activity was assessed. 14c-acetate 157-168 insulin Homo sapiens 201-208 12428690-3 2002 Synthesis of PAF was studied by combining the 14C-acetate incorporation into PAF with the quantitative analysis of PAF performed by a procedure based on gas chromatography-mass spectrometry with a negative ion chemical ionization. 14c-acetate 46-57 PCNA clamp associated factor Homo sapiens 13-16 12390813-5 2002 Significant inverse correlation was observed between IDE activity of IR cells and the incorporation rates of 14C-2-deoxyglucose and 14C-acetate. 14c-acetate 132-143 insulin degrading enzyme Rattus norvegicus 53-56 10405975-6 1999 Mevinolin (lovastatin), an inhibitor of 3-hydroxy-3-methylglutaryl-CoA(HMG-CoA) reductase, at 2 microM concentration, inhibited CH synthesis from 14C-acetate by 80%. 14c-acetate 146-157 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens 71-89 6868329-0 1983 Successful production and radioactive labeling 2 14C-acetate of "T-2" toxin on a liquid medium. 14c-acetate 49-60 solute carrier family 25 member 5 Homo sapiens 65-68 9785091-3 1997 Elastin appeared to inhibit the cholesterol synthesis in monocytes, measured by the incorporation of 14C-acetate. 14c-acetate 101-112 elastin Homo sapiens 0-7 8484956-4 1993 14C-Acetate incorporation into cholesterol of these fibroblasts was 27.8 +/- 9.4% that observed in normal fibroblasts, and the reduced cholesterol synthesis was confirmed by measuring the activity of the rate-limiting enzyme HMGCoA reductase which averaged 6.64 +/- 2.50 nmol/h/mg protein in the patient"s fibroblasts compared to 14.70 +/- 0.69 nmol/h/mg protein in the control fibroblasts. 14c-acetate 0-11 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens 225-241 6376245-5 1984 Cycloheximide (20 micrograms/ml), a translational inhibitor of protein synthesis, prevented the insulin-mediated increase in the enzyme activity and the incorporation of 14C-acetate into sterols. 14c-acetate 170-181 insulin Homo sapiens 96-103 10405973-5 1999 Furthermore, our 14C-acetate-labeling studies showed a 50% reduction in cholesteryl ester synthesis in the presence of either flavonoid, which could account for the reduction in net apoB secretion caused by incubation with these compounds. 14c-acetate 17-28 apolipoprotein B Homo sapiens 182-186 1505653-3 1992 Synthesis of C (as 14C-acetate incorporation) and of DNA (as 3H-thymidine incorporation) was clearly reduced, both in basal state and after PHA stimulation, in G-6-PD-deficient cells compared to normal cells. 14c-acetate 19-30 glucose-6-phosphate dehydrogenase Homo sapiens 160-166 3662811-8 1987 The results suggested that T-2 toxin inhibited the incorporation of 14C-acetate mainly into liver and its microsomal phospholipids and their subfractions in rats. 14c-acetate 68-79 brachyury 2 Rattus norvegicus 27-30 5531466-0 1970 [Effect of fat free diet on the incorporation of radioactivity intovarious fatty acid-moieties of lipids in liver slices incubated with 14C-acetate]. 14c-acetate 136-147 FAT atypical cadherin 1 Homo sapiens 11-14 986960-9 1976 Comparable quantitative fluctuations were found with the fractionated incorporation of 14C-acetate into the C21 and C18 steroids in the time sequence following hCG injection. 14c-acetate 87-98 hypertrichosis 2 (generalised, congenital) Homo sapiens 160-163 7086239-4 1982 Marked changes were not observed in the activity of plasma lipoprotein lipase in rabbits by the administration of o-PRL, but in in vitro experiments, the up-take of 14C-acetate into lipid fraction of rabbit liver slice significantly increased by the addition of o-PRL. 14c-acetate 165-176 prolactin Oryctolagus cuniculus 116-119 7086239-4 1982 Marked changes were not observed in the activity of plasma lipoprotein lipase in rabbits by the administration of o-PRL, but in in vitro experiments, the up-take of 14C-acetate into lipid fraction of rabbit liver slice significantly increased by the addition of o-PRL. 14c-acetate 165-176 prolactin Oryctolagus cuniculus 264-267 33420659-4 2021 The effect of polarizing stimuli on 14C-acetate uptake was determined by proinflammatory (interferon-gamma + lipopolysaccharide) vs inflammation-resolving (interleukin-4) stimulation of murine macrophages and human carotid endarterectomy specimens over 2 days. 14c-acetate 36-47 interferon gamma Mus musculus 90-106 33420659-6 2021 CD68-positive monocytes/macrophages vs smooth muscle actin-positive smooth muscle cells were the dominant cells in regions with high vs low 14C-acetate uptake. 14c-acetate 140-151 CD68 antigen Mus musculus 0-4 33420659-9 2021 Consistently, stimulation of endarterectomy specimens with interferon-gamma + lipopolysaccharide decreased 14C-acetate uptake to 66.5 +- 14.5%, while interleukin-4 increased 14C-acetate uptake to 151.5 +- 25.8% compared to non-stimulated plaques (P < .05). 14c-acetate 107-118 interferon gamma Homo sapiens 59-75 33420659-9 2021 Consistently, stimulation of endarterectomy specimens with interferon-gamma + lipopolysaccharide decreased 14C-acetate uptake to 66.5 +- 14.5%, while interleukin-4 increased 14C-acetate uptake to 151.5 +- 25.8% compared to non-stimulated plaques (P < .05). 14c-acetate 174-185 interferon gamma Homo sapiens 59-75 33420659-9 2021 Consistently, stimulation of endarterectomy specimens with interferon-gamma + lipopolysaccharide decreased 14C-acetate uptake to 66.5 +- 14.5%, while interleukin-4 increased 14C-acetate uptake to 151.5 +- 25.8% compared to non-stimulated plaques (P < .05). 14c-acetate 174-185 interleukin 4 Homo sapiens 150-163 16868926-5 2006 A decreased cholesterol synthesis and increased apoptosis was verified in experiments with human periovulatory granulosa cells treated with the PR antagonists Org 31710 or RU 486 by measuring caspase-3/7 activity and incorporation of 14C-acetate into cholesterol and progesterone. 14c-acetate 234-245 progesterone receptor Homo sapiens 144-146