PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 20090944-8 2010 B. pertussis-treated MDDC promoted a mixed Th1/Th17 polarization, and the activity of CyaA altered the Th1/Th17 balance, enhancing Th17 and limiting Th1 expansion. mddc 21-25 negative elongation factor complex member C/D Homo sapiens 43-46 12228279-7 2002 CT, LT, dibutyryl-cyclic-3",5"-AMP, and Forskolin also dominantly inhibit interleukin 12 and tumor necrosis factor alpha production by MDDC in the presence of saturating concentrations of lipopolysaccharide. mddc 135-139 tumor necrosis factor Homo sapiens 74-120 11751963-6 2002 In addition, Tat uptake is abolished or greatly hampered by oxidation/inactivation of the protein or by performing the experiments at 4 degrees C, suggesting that MDDC take up native Tat by a receptor-mediated endocytosis. mddc 163-167 tyrosine aminotransferase Homo sapiens 13-16 11751963-6 2002 In addition, Tat uptake is abolished or greatly hampered by oxidation/inactivation of the protein or by performing the experiments at 4 degrees C, suggesting that MDDC take up native Tat by a receptor-mediated endocytosis. mddc 163-167 tyrosine aminotransferase Homo sapiens 183-186 20937235-10 2010 ApoA-I also stimulated MDDC to produce IL-12 and TNF-alpha. mddc 23-27 apolipoprotein A1 Homo sapiens 0-6 20937235-10 2010 ApoA-I also stimulated MDDC to produce IL-12 and TNF-alpha. mddc 23-27 tumor necrosis factor Homo sapiens 49-58 24801497-7 2014 Nevertheless, Fha44 induced the secretion of IL-12p40, IL-12p70, IL-23 and IL-6 by MDDC, albeit at lower levels than FHA. mddc 83-87 interleukin 6 Homo sapiens 75-79 22973879-9 2012 BM4-pulsed mdDC induced enhanced proliferative responses at earlier time-points in Bet v 1-specific T-cell clones and promoted less IL-5 production in T cells than Bet v 1-pulsed mdDC. mddc 11-15 delta/notch like EGF repeat containing Homo sapiens 83-86 22973879-9 2012 BM4-pulsed mdDC induced enhanced proliferative responses at earlier time-points in Bet v 1-specific T-cell clones and promoted less IL-5 production in T cells than Bet v 1-pulsed mdDC. mddc 11-15 interleukin 5 Homo sapiens 132-136 22841385-7 2012 Exposure of mdDC to purified CarLA resulted in the increased production of the pro-inflammatory cytokines IL-6 and to a lesser extent of IL-8 and TNF-alpha, and a reduced production of the anti-inflammatory cytokine IL-1RA. mddc 12-16 interleukin 6 Homo sapiens 106-110 22841385-7 2012 Exposure of mdDC to purified CarLA resulted in the increased production of the pro-inflammatory cytokines IL-6 and to a lesser extent of IL-8 and TNF-alpha, and a reduced production of the anti-inflammatory cytokine IL-1RA. mddc 12-16 C-X-C motif chemokine ligand 8 Homo sapiens 137-141 22841385-7 2012 Exposure of mdDC to purified CarLA resulted in the increased production of the pro-inflammatory cytokines IL-6 and to a lesser extent of IL-8 and TNF-alpha, and a reduced production of the anti-inflammatory cytokine IL-1RA. mddc 12-16 tumor necrosis factor Homo sapiens 146-155 22841385-7 2012 Exposure of mdDC to purified CarLA resulted in the increased production of the pro-inflammatory cytokines IL-6 and to a lesser extent of IL-8 and TNF-alpha, and a reduced production of the anti-inflammatory cytokine IL-1RA. mddc 12-16 interleukin 1 receptor antagonist Homo sapiens 216-222 20090944-8 2010 B. pertussis-treated MDDC promoted a mixed Th1/Th17 polarization, and the activity of CyaA altered the Th1/Th17 balance, enhancing Th17 and limiting Th1 expansion. mddc 21-25 negative elongation factor complex member C/D Homo sapiens 47-50 20090944-8 2010 B. pertussis-treated MDDC promoted a mixed Th1/Th17 polarization, and the activity of CyaA altered the Th1/Th17 balance, enhancing Th17 and limiting Th1 expansion. mddc 21-25 negative elongation factor complex member C/D Homo sapiens 47-50 19578865-10 2010 These data also indicated that TLR3/4 agonists might be effective adjuvants of mdDC-based vaccines against CA. mddc 79-83 toll like receptor 3 Homo sapiens 31-35 20205699-9 2010 CONCLUSIONS: These results indicated that the inhibition of Der p-induced activation of MH-S and MDDC by SP-D is mediated through suppression of the CD14/TLR signalling pathway and maintenance of DC-SIGN expression, which may protect allergen-induced airway inflammation. mddc 97-101 surfactant associated protein D Mus musculus 105-109 17620093-9 2007 The antigen-presenting capacity was diminished in CoPP-treated and HO-1-transduced MDDC. mddc 83-87 heme oxygenase 1 Mus musculus 67-71 17675509-4 2007 BPI produced a dose-dependent increase (up to 3-fold) in delivery of (14)C-labeled blebs to MDDC, but not to monocyte-derived macrophages in the presence or absence of serum. mddc 92-96 bactericidal permeability increasing protein Homo sapiens 0-3 18161527-6 2007 Infected, but not uninfected, MDDC induced IFN-alpha in pDC. mddc 30-34 interferon alpha 1 Homo sapiens 43-52 15810889-8 2005 Conversely, the inhibition of ERK by the specific inhibitor (PD98059), but not the p-38 inhibitor SB203580, restored CD1a expression (P=0.011, n=4) in iC3b-stimulated MDDC. mddc 167-171 mitogen-activated protein kinase 1 Homo sapiens 30-33