PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
16480998-0	2006	Generation of nanostructures of mica supported lysozyme molecules in aqueous solution by atomic force microscopy.	mica	32-36	lysozyme	Homo sapiens	47-55
16621903-1	2006	CONTEXT: Major histocompatibility complex class I-related chains A and B (MICA/B) are two stress-inducible ligands for the immunoreceptor NKG2D that is expressed on cytotoxic T cells and natural killer (NK) cells.	mica	74-78	killer cell lectin like receptor K1	Homo sapiens	138-143
16621903-9	2006	MICA/B expression was detected in eight of 10 thyroid tumor cell lines and correlated with their sensitivity to killing by the NKG2/D-positive NK-92 cells.	mica	0-4	killer cell lectin like receptor C1	Homo sapiens	127-131
16621903-12	2006	Transient transfection of mutant BRAF and RAS oncogenes led to increased MICA/B expression in 293 cells and WRO82 cells.	mica	73-77	B-Raf proto-oncogene, serine/threonine kinase	Homo sapiens	33-37
16480998-1	2006	Nanostructures of lysozyme molecules adsorbed to mica were generated by the tip of an atomic force microscope in contact, tapping, and force-distance mode in aqueous solution.	mica	49-53	lysozyme	Homo sapiens	18-26
16480998-7	2006	It is postulated that reduction of electrostatic interaction between the oppositely charged lysozyme molecules and mica surface by sufficient high ionic strength is essential for monolayer formation.	mica	115-119	lysozyme	Homo sapiens	92-100
16480998-8	2006	It is discussed that for the underlying mechanism of monolayer generation in contact mode lysozyme molecules of the bulk phase adsorb to the tip, become pulled off and attach to the mica surface by the scan process of the tip.	mica	182-186	lysozyme	Homo sapiens	90-98
16756296-0	2006	Coexistence of liquid and solid phases of Bmim-PF6 ionic liquid on mica surfaces at room temperature.	mica	67-71	sperm associated antigen 17	Homo sapiens	47-50
16756296-1	2006	In this communication, we report the coexistence of liquid and solid phases of room temperature ionic liquid (IL) [Bmim][PF6] on mica surfaces, observed by tapping mode atomic force microscopy (AFM) in air.	mica	129-133	sperm associated antigen 17	Homo sapiens	121-124
16732660-5	2006	In particular, the morphology of the adsorbed nonquaternized 0qPDMA-PDEA copolymer micelles is clearly influenced by the substrate type: these micelles form a disordered layer on silica, while much more close-packed, highly ordered layers are obtained on mica.	mica	255-259	phosphodiesterase 6A	Homo sapiens	68-72
16706023-4	2006	RESULT: There was the tendency that mica monomer granule preparation with three different dosage could decrease the expression of p53 as well as p21, and mica had the obvious regulative effects on deletion of p16 and high-expression of bcl-2.	mica	36-40	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	130-133
16513776-1	2006	We have used a DNA-aptamer tethered to an atomic force microscope probe to carry out recognition imaging of IgE molecules attached to a mica substrate.	mica	136-140	immunoglobulin heavy constant epsilon	Homo sapiens	108-111
16706023-4	2006	RESULT: There was the tendency that mica monomer granule preparation with three different dosage could decrease the expression of p53 as well as p21, and mica had the obvious regulative effects on deletion of p16 and high-expression of bcl-2.	mica	36-40	KRAS proto-oncogene, GTPase	Rattus norvegicus	145-148
16706023-4	2006	RESULT: There was the tendency that mica monomer granule preparation with three different dosage could decrease the expression of p53 as well as p21, and mica had the obvious regulative effects on deletion of p16 and high-expression of bcl-2.	mica	36-40	BCL2, apoptosis regulator	Rattus norvegicus	236-241
16706023-4	2006	RESULT: There was the tendency that mica monomer granule preparation with three different dosage could decrease the expression of p53 as well as p21, and mica had the obvious regulative effects on deletion of p16 and high-expression of bcl-2.	mica	154-158	cyclin-dependent kinase inhibitor 2A	Rattus norvegicus	209-212
16706023-4	2006	RESULT: There was the tendency that mica monomer granule preparation with three different dosage could decrease the expression of p53 as well as p21, and mica had the obvious regulative effects on deletion of p16 and high-expression of bcl-2.	mica	154-158	BCL2, apoptosis regulator	Rattus norvegicus	236-241
16617021-2	2006	Most of the mica-adsorbed alpha-Syn fibrils disassemble into small particles step-by-step on the mica surface in diluted solutions, yet a few short fibrils still extend to form longer fibrils.	mica	12-16	synuclein alpha	Homo sapiens	26-35
16617021-2	2006	Most of the mica-adsorbed alpha-Syn fibrils disassemble into small particles step-by-step on the mica surface in diluted solutions, yet a few short fibrils still extend to form longer fibrils.	mica	97-101	synuclein alpha	Homo sapiens	26-35
15909285-2	2005	The interactions between protein bovine vitronectin layers adsorbed onto a silica probe and a mica surface have been investigated with the use of atomic force microscopy (AFM).	mica	94-98	vitronectin	Bos taurus	40-51
16322264-1	2005	We show that histone deacetylase (HDAC) inhibitors lead to functional expression of MHC class I-related chain A and B (MICA/B) on cancer cells, making them potent targets for natural killer (NK) cell-mediated killing through a NK group 2, member D (NKG2D) restricted mechanism.	mica	119-123	histone deacetylase 9	Homo sapiens	13-32
16322264-1	2005	We show that histone deacetylase (HDAC) inhibitors lead to functional expression of MHC class I-related chain A and B (MICA/B) on cancer cells, making them potent targets for natural killer (NK) cell-mediated killing through a NK group 2, member D (NKG2D) restricted mechanism.	mica	119-123	histone deacetylase 9	Homo sapiens	34-38
16322264-1	2005	We show that histone deacetylase (HDAC) inhibitors lead to functional expression of MHC class I-related chain A and B (MICA/B) on cancer cells, making them potent targets for natural killer (NK) cell-mediated killing through a NK group 2, member D (NKG2D) restricted mechanism.	mica	119-123	killer cell lectin like receptor K1	Homo sapiens	249-254
16322264-3	2005	HDAC inhibitor treatment induced glycogen synthase kinase-3 (GSK-3) activity and down-regulation of GSK-3 by small interfering RNA or by different inhibitors showed that GSK-3 activity is essential for the induced MICA/B expression.	mica	214-218	histone deacetylase 9	Homo sapiens	0-4
16085777-2	2005	We previously found that annexin A5 self-assembles into two-dimensional (2D) crystals on supported lipid bilayers (SLBs) formed on mica while a monolayer of disordered trimers is formed on SLBs on silica.	mica	131-135	annexin A5	Homo sapiens	25-35
16085777-3	2005	Here, we investigated in detail and correlated the adsorption kinetics of annexin A5 on SLBs, supported on silica and on mica, with the protein"s 2D self-assembly behavior.	mica	121-125	annexin A5	Homo sapiens	74-84
16207028-1	2005	The adsorption of a biologically important glycoprotein, mucin, and mucin-chitosan complex layer formation on negatively charged surfaces, silica and mica, have been investigated employing ellipsometry, the interferometric surface apparatus, and atomic force microscopy techniques.	mica	150-154	LOC100508689	Homo sapiens	68-73
16002667-3	2005	Although MICA functions as a potent activating ligand of mouse NKG2D, H2-K(b)-MICA mice appear healthy without aberrations in lymphocyte subsets.	mica	9-13	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	63-68
16002667-3	2005	Although MICA functions as a potent activating ligand of mouse NKG2D, H2-K(b)-MICA mice appear healthy without aberrations in lymphocyte subsets.	mica	78-82	histocompatibility 2, K1, K region	Mus musculus	70-76
16002667-4	2005	However, NKG2D-mediated cytotoxicity of H2-K(b)-MICA NK cells is severely impaired in vitro and in vivo.	mica	48-52	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	9-14
16002667-4	2005	However, NKG2D-mediated cytotoxicity of H2-K(b)-MICA NK cells is severely impaired in vitro and in vivo.	mica	48-52	histocompatibility 2, K1, K region	Mus musculus	40-46
16002667-6	2005	As a consequence, H2-K(b)-MICA mice fail to reject MICA-expressing tumors and to mount normal CD8 T cell responses upon Listeria infection emphasizing the importance of NKG2D in immunity against tumors and intracellular infectious agents.	mica	26-30	histocompatibility 2, K1, K region	Mus musculus	18-24
16002667-6	2005	As a consequence, H2-K(b)-MICA mice fail to reject MICA-expressing tumors and to mount normal CD8 T cell responses upon Listeria infection emphasizing the importance of NKG2D in immunity against tumors and intracellular infectious agents.	mica	26-30	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	169-174
16002667-6	2005	As a consequence, H2-K(b)-MICA mice fail to reject MICA-expressing tumors and to mount normal CD8 T cell responses upon Listeria infection emphasizing the importance of NKG2D in immunity against tumors and intracellular infectious agents.	mica	51-55	histocompatibility 2, K1, K region	Mus musculus	18-24
15450850-3	2004	When mature vimentin IFs were imaged in air on mica, they appeared to have a width of approximately 28 nm, a height of approximately 4 nm and a length of several micrometers.	mica	47-51	vimentin	Mus musculus	12-20
15758205-3	2005	In chimpanzees, however, only one MIC gene is expressed, showing an intermediate character, resulting from a deletion fusing the MICA and MICB gene segments together.	mica	129-133	MHC class I polypeptide-related sequence B	Pan troglodytes	34-37
15835980-1	2005	Molecular force spectroscopy was used to study the mechanical behavior of plasma fibronectin (FN) on mica, gold, poly(ethylene glycol), and -CH(3), -OH, and -COOH terminated alkanethiol self-assembled monolayers.	mica	101-105	fibronectin 1	Homo sapiens	81-92
15835980-1	2005	Molecular force spectroscopy was used to study the mechanical behavior of plasma fibronectin (FN) on mica, gold, poly(ethylene glycol), and -CH(3), -OH, and -COOH terminated alkanethiol self-assembled monolayers.	mica	101-105	fibronectin 1	Homo sapiens	94-96
15784682-6	2005	The interaction force (force required to break a single AbII-13/HSP60 bond) was 59+/-2 pN, which correlated nicely to the 51+/-1 pN measured with isolated HSP60 attached to mica surfaces.	mica	173-177	heat shock protein family D (Hsp60) member 1	Homo sapiens	64-69
15784682-6	2005	The interaction force (force required to break a single AbII-13/HSP60 bond) was 59+/-2 pN, which correlated nicely to the 51+/-1 pN measured with isolated HSP60 attached to mica surfaces.	mica	173-177	heat shock protein family D (Hsp60) member 1	Homo sapiens	155-160
15698989-2	2005	METHODS: AFM was used to acquire the images of SPA-G binding to the surface of mica under physiological condition for determining the 3D conformation of the molecule.	mica	79-83	surfactant protein A1	Homo sapiens	47-50
15666410-10	2005	Additionally, protein conformation and assembly orientation on these surfaces were documented where fibrinogen on HOPG formed a network-like structure, whereas fibrinogen on mica was more random.	mica	174-178	fibrinogen beta chain	Homo sapiens	160-170
15379516-1	2004	Tapping-mode atomic force microscopy was used to study the time-dependent changes in the structure of fibrinogen under aqueous conditions following adsorption on two model surfaces: hydrophobic graphite and hydrophilic mica.	mica	219-223	fibrinogen beta chain	Homo sapiens	102-112
15212902-5	2004	CL-20 abiotically degrades in oxic environments at slow rates (i.e., 10s to 100s of hours) with a wide variety of minerals, but at fast rates (i.e., minutes) in the presence of 2:1 phyllosilicate clays (hectorite, montmorillonite, nontronite), micas (biotite, illite), and specific oxides (MnO2 and the ferrous-ferric iron oxide magnetite).	mica	244-249	epithelial membrane protein 1	Homo sapiens	0-5
15342243-0	2004	Atomic force microscopy reveals defects within mica supported lipid bilayers induced by the amyloidogenic human amylin peptide.	mica	47-51	islet amyloid polypeptide	Homo sapiens	112-118
15142590-5	2004	A solution containing ER-alpha was dropped onto the Ni-treated mica substrate on which the DNA prove was previously immobilized, and it was observed by AFM.	mica	63-67	estrogen receptor 1	Homo sapiens	22-30
15835139-6	2004	The BEn surfactants are only weakly attracted to hydrophilic surfaces, more on oxidized silicon than on mica.	mica	104-108	GTF2I repeat domain containing 1	Homo sapiens	4-7
15706923-1	2004	OBJECTIVE: To study regulative action of mica monomer granule preparation on gastrin (GAS), somatostatin (SS) and G cells as well as D cells of gastric mucosa in experimental chronic atrophic gastritis (CAG) rat.	mica	41-45	gastrin	Rattus norvegicus	77-84
15706923-1	2004	OBJECTIVE: To study regulative action of mica monomer granule preparation on gastrin (GAS), somatostatin (SS) and G cells as well as D cells of gastric mucosa in experimental chronic atrophic gastritis (CAG) rat.	mica	41-45	somatostatin	Rattus norvegicus	92-104
15706923-4	2004	RESULT: Mica monomer granule of three different dosages could increase the quantity of G cells as well as D cells of gastric mucosa and the concentration of blood serum GAS and decrease the content of blood plasma SS in CAG rat at different level respectively.	mica	8-12	gastrin	Rattus norvegicus	169-172
15969416-3	2004	The CT salt of the amphiphilic bis(TTF)-macrocycle having a [24]crown-8 ring system formed a uniform surface morphology on mica.	mica	123-127	ras homolog family member H	Homo sapiens	35-38
15969416-9	2004	Further reduction of the macrocyclic ring from [21]crown-7 to [18]crown-6 resulted in a CT salt of the bis(TTF)-macrocycle with F4-TCNQ with a leaf-shape domain morphology and a typical dimension of approximately 1 microm2 on mica.	mica	226-230	ras homolog family member H	Homo sapiens	107-110
15162429-1	2004	Mill (MHC class I-like located near the leukocyte receptor complex) is a novel family of class I genes identified in mice that is most closely related to the human MICA/B family.	mica	164-168	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	Mus musculus	10-17
15162429-1	2004	Mill (MHC class I-like located near the leukocyte receptor complex) is a novel family of class I genes identified in mice that is most closely related to the human MICA/B family.	mica	164-168	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	Mus musculus	89-96
14607946-1	2003	We previously reported that monocyte-derived dendritic cells activate resting NK cells by expressing MHC class I-related chain A and B (MICA/B), ligands for NKG2D, in response to IFN-alpha, but the MICA/B expression was severely impaired in patients with chronic hepatitis C virus (HCV) infection.	mica	136-140	interferon alpha 1	Homo sapiens	179-188
14762927-3	2004	In this study, adsorption of Vn molecules on mica and oxidized titanium substrates in Milli-Q water (pH 5.6) and in simulated body fluid (SBF, pH 7.4) has been investigated using tapping mode atomic force microscopy.	mica	45-49	vitronectin	Homo sapiens	29-31
14762927-7	2004	After 15 min of adsorption, globular Vn molecules form clusters of aggregates in extended chains on the mica surface.	mica	104-108	vitronectin	Homo sapiens	37-39
14762927-11	2004	The larger contact areas of Vn associated with Ti substrates indicates higher affinity for the biomaterial oxidized titanium surface than for mica.	mica	142-146	vitronectin	Homo sapiens	28-30
14762927-12	2004	In SBF, Vn interacted weakly with the mica surfaces and Vn molecules were easily desorbed during the imaging process.	mica	38-42	vitronectin	Homo sapiens	8-10
15518340-3	2004	As one of the activating receptors, NKG2D recognises some self ligands such as MICA/B in human and Rae1 in mice, which is dissimilar to those toll-like receptors that recognise some pathogen-derived ligands.	mica	79-83	killer cell lectin like receptor K1	Homo sapiens	36-41
15487690-0	2004	Effect of the shape of mica particles on the production of tumor necrosis factor alpha in mouse macrophages.	mica	23-27	tumor necrosis factor	Mus musculus	59-86
14607946-1	2003	We previously reported that monocyte-derived dendritic cells activate resting NK cells by expressing MHC class I-related chain A and B (MICA/B), ligands for NKG2D, in response to IFN-alpha, but the MICA/B expression was severely impaired in patients with chronic hepatitis C virus (HCV) infection.	mica	136-140	killer cell lectin like receptor K1	Homo sapiens	157-162
14607946-2	2003	In the present study, we examined induction of MICA/B on DCs by various innate cytokines and found that DCs from either healthy donors or HCV-infected individuals, upon IL-15 stimulation, express MICA/B and can activate NK cells, which is solely dependent on MICA/B-NKG2D interaction.	mica	47-51	interleukin 15	Homo sapiens	169-174
14607946-3	2003	Of interest is the finding that IL-15- and type I IFN-mediated induction of MICA/B in healthy donors is completely inhibited when DCs are incubated in the presence of anti-IFN-alpha/betaR or anti-IL-15Ralpha, respectively, suggesting interdependent roles of these cytokines in MICA/B expression.	mica	76-80	interleukin 15	Homo sapiens	32-54
14607946-3	2003	Of interest is the finding that IL-15- and type I IFN-mediated induction of MICA/B in healthy donors is completely inhibited when DCs are incubated in the presence of anti-IFN-alpha/betaR or anti-IL-15Ralpha, respectively, suggesting interdependent roles of these cytokines in MICA/B expression.	mica	76-80	interferon alpha 1	Homo sapiens	172-187
14607946-3	2003	Of interest is the finding that IL-15- and type I IFN-mediated induction of MICA/B in healthy donors is completely inhibited when DCs are incubated in the presence of anti-IFN-alpha/betaR or anti-IL-15Ralpha, respectively, suggesting interdependent roles of these cytokines in MICA/B expression.	mica	76-80	interleukin 15 receptor subunit alpha	Homo sapiens	196-207
14607946-3	2003	Of interest is the finding that IL-15- and type I IFN-mediated induction of MICA/B in healthy donors is completely inhibited when DCs are incubated in the presence of anti-IFN-alpha/betaR or anti-IL-15Ralpha, respectively, suggesting interdependent roles of these cytokines in MICA/B expression.	mica	277-281	interleukin 15	Homo sapiens	32-54
14607946-3	2003	Of interest is the finding that IL-15- and type I IFN-mediated induction of MICA/B in healthy donors is completely inhibited when DCs are incubated in the presence of anti-IFN-alpha/betaR or anti-IL-15Ralpha, respectively, suggesting interdependent roles of these cytokines in MICA/B expression.	mica	277-281	interferon alpha 1	Homo sapiens	172-187
14607946-3	2003	Of interest is the finding that IL-15- and type I IFN-mediated induction of MICA/B in healthy donors is completely inhibited when DCs are incubated in the presence of anti-IFN-alpha/betaR or anti-IL-15Ralpha, respectively, suggesting interdependent roles of these cytokines in MICA/B expression.	mica	277-281	interleukin 15 receptor subunit alpha	Homo sapiens	196-207
14607946-6	2003	The present study demonstrates that IL-15 and type I IFN lead to DC expression of MICA/B and subsequent DC activation of NK cells, which is critically dependent on each other"s autocrine/paracrine effect, and suggests that impaired IL-15 production is one of the mechanisms of the aberrant response of DC to type I IFN in HCV-infected patients.	mica	82-86	interleukin 15	Homo sapiens	36-41
14607946-6	2003	The present study demonstrates that IL-15 and type I IFN lead to DC expression of MICA/B and subsequent DC activation of NK cells, which is critically dependent on each other"s autocrine/paracrine effect, and suggests that impaired IL-15 production is one of the mechanisms of the aberrant response of DC to type I IFN in HCV-infected patients.	mica	82-86	interleukin 15	Homo sapiens	232-237
12801682-2	2003	Investigations were carried out to find the concentration of NiCl(2) required to immobilize mucin molecules on a freshly cleaved mica surface, for imaging using intermittent contact in air.	mica	129-133	LOC100508689	Homo sapiens	92-97
12956881-1	2003	A large proportion of Japanese with the HLA-B48 allele have a MICA gene deletion associated with a MICB null allele within the class I region of the Major Histocompatibility Complex (MHC).	mica	62-66	MHC class I polypeptide-related sequence B	Homo sapiens	99-103
12757384-3	2003	After adhesion to the mica surface, both liposomes without fibrinogen and liposomes with attached fibrinogen collapsed into patches.	mica	22-26	fibrinogen beta chain	Homo sapiens	59-69
12829503-3	2003	To measure a specific and delicate interaction force, we obtained force curves without pressing the probe onto GroEL molecules spread on a mica surface.	mica	139-143	heat shock protein family D (Hsp60) member 1	Homo sapiens	111-116
12757384-3	2003	After adhesion to the mica surface, both liposomes without fibrinogen and liposomes with attached fibrinogen collapsed into patches.	mica	22-26	fibrinogen beta chain	Homo sapiens	98-108
12707750-3	2003	The adsorption of proteins leads to changes in topography, which was monitored for the build up of protein layers of hen egg-white lysozyme and bovine serum albumin (BSA) on mica in real time in phosphate-buffered aqueous solution over a time period of 10 min.	mica	174-178	albumin	Homo sapiens	151-164
12839652-0	2003	[Coloration of mica glass ceramic for use in dental CAD/CAM system].	mica	15-19	calmodulin 3	Homo sapiens	56-59
12839652-3	2003	RESULTS: Factors influencing the color appearance of mica glass ceramic were nucleation agent and the ratio of Mg(2+) to K(+) in base formula; Cerium oxide (CeO(2)) was used as the main coloration; The preferred heat treatment was 650 degrees C for 1 h and 1,000 degrees C or 1,050 degrees C for 3 h - 4 h. CONCLUSIONS: This mica glass-ceramic could provide 4 to 5 color appearance for dental use, it showed excellent machinability which was eminently suitable for use in dental CAD/CAM system.	mica	53-57	calmodulin 3	Homo sapiens	483-486
12373294-15	2002	This finding sheds light on the role of a receptor for MICA, named NKG2D, presented by natural killer cells, and CD8+, alphabetaT cells and gammadeltaT cells, usually localised in gut mucosa.	mica	55-59	killer cell lectin like receptor K1	Homo sapiens	67-72
15098660-7	2003	This is demonstrated by imaging myosin V molecules moving on mica, in solution.	mica	61-65	myosin VA	Homo sapiens	32-40
12522822-0	2003	Surface-dependent conformations of human plasma fibronectin adsorbed to silica, mica, and hydrophobic surfaces, studied with use of Atomic Force Microscopy.	mica	80-84	fibronectin 1	Homo sapiens	48-59
12522822-3	2003	Electron microscopy images of Fn air-sprayed onto mica surfaces show elongated protein structures, indicating a surface-induced structural change.	mica	50-54	fibronectin 1	Homo sapiens	30-32
12522822-5	2003	We have used intermittent-contact Atomic Force Microscopy to investigate the structure of Fn adsorbed onto mica, silica, and methylated silica surfaces.	mica	107-111	fibronectin 1	Homo sapiens	90-92
12538683-4	2003	Alternatively, MHC class I-related chain A and B (MICA/B), ligands for NKG2D activating receptor, were found to be induced on DCs upon IFN-alpha stimulation and to be responsible for the NK activation because mAb-mediated masking of MICA/B as well as inhibition of direct cell-to-cell contact using transwell insert completely abolished DC-dependent NK cell activation by IFN-alpha.	mica	50-54	interferon alpha 1	Homo sapiens	135-144
12538683-4	2003	Alternatively, MHC class I-related chain A and B (MICA/B), ligands for NKG2D activating receptor, were found to be induced on DCs upon IFN-alpha stimulation and to be responsible for the NK activation because mAb-mediated masking of MICA/B as well as inhibition of direct cell-to-cell contact using transwell insert completely abolished DC-dependent NK cell activation by IFN-alpha.	mica	50-54	interferon alpha 1	Homo sapiens	372-381
12538683-4	2003	Alternatively, MHC class I-related chain A and B (MICA/B), ligands for NKG2D activating receptor, were found to be induced on DCs upon IFN-alpha stimulation and to be responsible for the NK activation because mAb-mediated masking of MICA/B as well as inhibition of direct cell-to-cell contact using transwell insert completely abolished DC-dependent NK cell activation by IFN-alpha.	mica	233-237	interferon alpha 1	Homo sapiens	135-144
12538683-6	2003	These findings suggested that MICA/B induction on DCs may be one of the mechanisms by which IFN-alpha activates NK cells; this impairment might affect IFN-alpha responsiveness in hepatitis C virus infection.	mica	30-34	interferon alpha 1	Homo sapiens	92-101
12538683-6	2003	These findings suggested that MICA/B induction on DCs may be one of the mechanisms by which IFN-alpha activates NK cells; this impairment might affect IFN-alpha responsiveness in hepatitis C virus infection.	mica	30-34	interferon alpha 1	Homo sapiens	151-160
12356747-3	2002	SMA formed fibrils on native mica at pH 5.0, conditions under which predominantly amorphous aggregates form in solution.	mica	29-33	survival of motor neuron 1, telomeric	Homo sapiens	0-3
12235484-6	2002	Atomic force microscopy (AFM) of syncollin on mica supports at pH 7.6 showed particles of molecular volume 155 nm(3).	mica	46-50	syncollin	Homo sapiens	33-42
12202389-7	2002	By modifying the worm-like chain model for applicability to two dimensions, we have confirmed that under the conditions employed mucin adsorbs to mica in an equilibrated conformation.	mica	146-150	LOC100508689	Homo sapiens	129-134
12144820-1	2002	OBJECTIVE: In a previous study using the same cases of squamous cervical neoplasia and microinvasive carcinoma (MICA) we found an association between FHIT gene deletion and infection with high-risk HPV (HR HPV).	mica	112-116	fragile histidine triad diadenosine triphosphatase	Homo sapiens	150-154
12144820-5	2002	RESULTS: Fifty percent (14/28) of CIN3 lesions and 78% (18/23) of MICA lesions had a marked reduction or absence of Fhit protein expression (P = <0.001, strength of association, Cramers" V, 0.632).	mica	66-70	fragile histidine triad diadenosine triphosphatase	Homo sapiens	116-120
12144820-8	2002	A significant statistical relationship was found between Fhit protein expression and HPV 16 infection in combined CIN1, CIN3, and MICA cases (P = <0.001).	mica	130-134	fragile histidine triad diadenosine triphosphatase	Homo sapiens	57-61
12133944-4	2002	Soluble MICA tetramers were used as a binding reagent to demonstrate specific interactions with various V(delta)1 gamma delta TCRs expressed on transfectants of a T cell line selected for lack of NKG2D.	mica	8-12	killer cell lectin like receptor K1	Homo sapiens	196-201
11718557-2	2001	The divalent cation Mg(2+) was used to loosely attach both DNA and p53 to a mica surface so they could be imaged by the AFM while interacting with each other.	mica	76-80	tumor protein p53	Homo sapiens	67-70
11981900-14	2002	2: STM image (819x819 nm2) of a monolayer of [Cu.3]+ on Au(111) on mica.	mica	67-71	sulfotransferase family 1A member 3	Homo sapiens	3-6
12021142-9	2002	The test of the strongest association of the MICA A5 allele and TNF-alpha allele 2 with IDDM showed that both are independently associated with the disease.	mica	45-49	tumor necrosis factor	Homo sapiens	64-73
12096896-5	2002	Our preliminary studies confirm that (1) the intact receptor can be reconstituted constitutively within a lipid vesicle and (2) fusion of the receptor-containing vesicles to mica resulted in the formation of molecular flat 5.5-nm-thick supported planar bilayers populated by two populations of protrusions, the shape and size of which are consistent with those of the insulin receptor"s intra- and extracellular domains as modeled by the cryo-EM data of Ottensmeyer et al.	mica	174-178	insulin receptor	Homo sapiens	368-384
11977407-1	2002	Atomic force microscopy was used to study adsorption and adhesion peculiarities of interferon alpha-2a on glass and mica surfaces.	mica	116-120	interferon alpha 2	Homo sapiens	83-102
11908853-4	2002	CFTR-containing liposomes in solution were deposited on freshly cleaved mica and imaging was performed in tapping-mode AFM.	mica	72-76	CF transmembrane conductance regulator	Homo sapiens	0-4
11309099-2	2001	Monolayers deposited onto mica substrates at a surface pressure of 15 mN m-1 exhibit a two-phase coexistence across a broad range of SP-B(1-25) concentrations.	mica	26-30	surfactant protein B	Homo sapiens	133-137
11410278-6	2001	2-D crystallisation of the Prx-II protein on mica as part of a TEM study resulted in the formation of a p2 crystal form with parallel linear arrays of stacked rings.	mica	45-49	peroxiredoxin 2	Homo sapiens	27-33
10494763-8	1999	Quantitative dimensional analysis, which yielded structural information in three dimensions, indicates that surface-dependent structural deformation or spreading of fibrinogen increases according to the order: mica < APTES < OTS.	mica	210-214	fibrinogen beta chain	Homo sapiens	165-175
11969944-1	1999	Thick layers of the protein lysozyme have been deposited on mica, and their force-distance hysteresis measured using atomic force microscopy in the presence of different salts.	mica	60-64	lysozyme	Homo sapiens	28-36
10932247-2	2000	In particular, we have observed individual molecules of the chaperonin protein GroES binding to and then dissociating from individual GroEL proteins, which were immobilized on a mica support.	mica	178-182	heat shock protein family E (Hsp10) member 1	Homo sapiens	79-84
10932247-2	2000	In particular, we have observed individual molecules of the chaperonin protein GroES binding to and then dissociating from individual GroEL proteins, which were immobilized on a mica support.	mica	178-182	heat shock protein family D (Hsp60) member 1	Homo sapiens	134-139
18345192-5	2000	We use these roughness equations to determine the roughness of cleaved muscovite mica [essentially, KAl(2)(OH)(2)Si(3)AlO(10)]; the calculated values for both two- and three-dimensional roughness are consistent with those obtained in our AFM measurements.	mica	81-85	anosmin 1	Homo sapiens	100-103
10097098-1	1999	We have applied in situ atomic force microscopy to directly observe the aggregation of Alzheimer"s beta-amyloid peptide (Abeta) in contact with two model solid surfaces: hydrophilic mica and hydrophobic graphite.	mica	182-186	amyloid beta precursor protein	Homo sapiens	99-119
10097098-1	1999	We have applied in situ atomic force microscopy to directly observe the aggregation of Alzheimer"s beta-amyloid peptide (Abeta) in contact with two model solid surfaces: hydrophilic mica and hydrophobic graphite.	mica	182-186	amyloid beta precursor protein	Homo sapiens	121-126
10097098-5	1999	On hydrophilic mica, Abeta formed particulate, pseudomicellar aggregates, which at higher Abeta concentration had the tendency to form linear assemblies, reminiscent of protofibrillar species described recently in the literature.	mica	15-19	amyloid beta precursor protein	Homo sapiens	21-26
10097098-5	1999	On hydrophilic mica, Abeta formed particulate, pseudomicellar aggregates, which at higher Abeta concentration had the tendency to form linear assemblies, reminiscent of protofibrillar species described recently in the literature.	mica	15-19	amyloid beta precursor protein	Homo sapiens	90-95
9916039-0	1999	Force measurements on myelin basic protein adsorbed to mica and lipid bilayer surfaces done with the atomic force microscope.	mica	55-59	myelin basic protein	Bos taurus	22-42
9916039-6	1999	While attached to the mica surface, the MBP molecules exhibited elastic stretching behavior that agreed with the worm-like chain model, yielding a persistence length of 0.5 +/- 0.25 nm and an average contour length of 53 +/- 19 nm.	mica	22-26	myelin basic protein	Bos taurus	40-43
9878384-3	1999	By time-lapse atomic force microscopy (AFM), the growth of individual amylin fibrils on a mica surface was observed over several hours.	mica	90-94	islet amyloid polypeptide	Homo sapiens	70-76
10576601-2	1999	AChE and ACh were covalently immobilized onto the surfaces of gold-plated mica and Si3N4 tip of the atomic force microscope respectively.	mica	74-78	acetylcholinesterase (Cartwright blood group)	Homo sapiens	0-4
10780466-2	1999	RecA and DNA were reacted under several conditions, and deposited onto a mica substrate pre-treated in various ways.	mica	73-77	RAD51 recombinase	Homo sapiens	0-4
9548925-3	1998	Insulin molecules, modified with a photochemically active azido functionality on specific residues, were attached to force microscope tips and opposing mica surfaces in configurations that would either favor or disfavor dimer formation.	mica	43-47	insulin	Homo sapiens	0-7
9698416-1	1998	The short-range interaction force between a mica surface and an AFM probe tip in electrolyte solutions was measured by atomic force microscopy (AFM) to directly evaluate the thickness of the adsorbed layer on the surface.	mica	44-48	TOR signaling pathway regulator	Homo sapiens	74-77
9267032-1	1997	Using quick-freeze/deep-etch electron microscopy of recombinant proteins adsorbed to mica, we show that NSF, the oligomeric ATPase involved in membrane fusion, is a hollow 10 x 16 nm cylinder whose conformation depends upon nucleotide binding.	mica	85-89	N-ethylmaleimide sensitive factor, vesicle fusing ATPase	Homo sapiens	104-107
9635779-2	1998	High-resolution images can be obtained, which show the up-right position of GroEL adsorbed on mica with the substrate-binding site on top.	mica	94-98	GroEL	Escherichia coli	76-81
9768470-6	1997	Purified human fibrinogen, together with 15-nm colloidal gold particles serving as an internal calibration standard, were adhered to a poly-L-lysine substrate on freshly cleaved mica.	mica	178-182	fibrinogen beta chain	Homo sapiens	15-25
8641460-1	1996	alpha2-Macroglobulin was derivatized with a sulfhydryl cross-linker and sandwiched between a mica substrate and a silicon nitride tip, both coated with gold, of an atomic force microscope and force curve measurement was carried out.	mica	93-97	alpha-2-macroglobulin	Homo sapiens	0-20
8889197-2	1996	We demonstrate that both GroEL and GroES that have been adsorbed to a mica surface can be resolved directly by the AFM in aqueous solution at room temperature.	mica	70-74	GroEL	Escherichia coli	25-30
8889197-2	1996	We demonstrate that both GroEL and GroES that have been adsorbed to a mica surface can be resolved directly by the AFM in aqueous solution at room temperature.	mica	70-74	chaperonin GroES	Escherichia coli	35-40
8710944-10	1996	In experiments on ROMK1 in aqueous solution, single molecules appear to aggregate, but contact to the mica was maintained.	mica	102-106	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	18-23
8816973-8	1996	The high relative avidities for GAD65 of MICA 1, 3, 4 and 6 and their high, nonrandom ratio of replacement versus silent mutations in the antigen binding regions indicated that the humoral response to GAD65 is driven by the antigen.	mica	41-45	glutamate decarboxylase 2	Homo sapiens	32-37
8816973-8	1996	The high relative avidities for GAD65 of MICA 1, 3, 4 and 6 and their high, nonrandom ratio of replacement versus silent mutations in the antigen binding regions indicated that the humoral response to GAD65 is driven by the antigen.	mica	41-45	glutamate decarboxylase 2	Homo sapiens	201-206
8957788-0	1996	Mechanical properties of a new mica-based machinable glass ceramic for CAD/CAM restorations.	mica	31-35	calmodulin 3	Homo sapiens	75-78
8785352-3	1996	The transition metal cations that effectively bind DNA to mica are Ni(II), Co(II), and Zn(II), which have ionic radii from 0.69 to 0.74 A.	mica	58-62	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	75-81
8785352-10	1996	Ni(II), Co(II), and Zn(II) have anomalously high enthalpies of hydration that may relate to their ability to bind DNA to mica.	mica	121-125	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	8-14
8714736-4	1995	We demonstrate that single or multiple rabbit anti-human serum albumin molecules form complexes with preadsorbed single human serum albumin molecules on mica.	mica	153-157	albumin	Homo sapiens	57-70
7577227-1	1995	Negatively stained electron microscope images are presented, showing the nucleation of two-dimensional (2-D) crystals of human erythrocyte catalase produced on mica by the negative staining-carbon film technique.	mica	160-164	catalase	Homo sapiens	139-147
8714736-4	1995	We demonstrate that single or multiple rabbit anti-human serum albumin molecules form complexes with preadsorbed single human serum albumin molecules on mica.	mica	153-157	albumin	Homo sapiens	126-139
2061408-6	1991	Our observations also suggested the presence of a rather rigid 30-40 nm stretch in the middle of the caldesmon molecule, which was always visible under rotary shadowing, and a flexible structure of about 20 nm in length at each end of the molecule, which may or may not be visible depending on their orientation on the mica surface.	mica	319-323	caldesmon 1	Gallus gallus	101-110
8079171-1	1994	The height fluctuations on top of the protein lysozyme adsorbed on mica were measured locally with an atomic force microscope operated in tapping mode in liquid.	mica	67-71	lysozyme	Homo sapiens	46-54
2261309-3	1990	When protein solutions were sprayed on mica sheets and then heated to melt alpha-helices, myosin molecules did not show any sign of chain separation but appeared to have collapsed into loose clumps.	mica	39-43	myosin heavy chain 14	Homo sapiens	90-96
35119498-9	2022	Importantly, EVs from cytokine-stimulated NK cells penetrate into the spheroid core, and tumor spheroid susceptibility to NK-cell derived EVs was linked to differential expression of the NKG2D ligands MICA/B, which was blocked with an anti-NKG2D antibody.	mica	201-205	killer cell lectin like receptor K1	Homo sapiens	187-192
33779082-2	2021	NKG2D is the most important activating receptor expressed on the NK cell surface; this receptor binds to the ligands MICA/B and ULBPs to activate NK cells.	mica	117-121	killer cell lectin like receptor K1	Homo sapiens	0-5
27655504-1	2016	This study explored the expression of interleukin 17D (IL-17D) secreted by human ovariancarcinoma cells and the effect of exogenous IL-17D transfection on MICA, which is the ligand of NKG2D, on the surface of ovary carcinoma cells.	mica	155-159	interleukin 17D	Homo sapiens	132-138
25526818-8	2015	Similarly, the results show that Sal suppressed cytotoxicity of both CD8 T and NK cells in vitro following stimulation with Chinese hamster ovary cell line transfected with MICA(*009) (T-CHO) and the human erythromyeloblastoid leukemic (K562) cell line.	mica	173-177	CD8a molecule	Homo sapiens	69-72
34766499-4	2021	By testing and comparing aMD4 synthesized with linkers of different lengths and rigidities, we maximize the interaction between the functionalized tip and hMET added to both a mica surface and supported lipid bilayers.	mica	176-180	TOR signaling pathway regulator	Homo sapiens	147-150
34766499-4	2021	By testing and comparing aMD4 synthesized with linkers of different lengths and rigidities, we maximize the interaction between the functionalized tip and hMET added to both a mica surface and supported lipid bilayers.	mica	176-180	SAFB like transcription modulator	Homo sapiens	155-159
35393416-5	2022	In the HNSCC model we demonstrate that CHMP2A mediates tumor resistance to NK cells via secretion of extracellular vesicles (EVs) that express MICA/B and TRAIL.	mica	143-147	charged multivesicular body protein 2A	Homo sapiens	39-45
35309907-8	2022	Furthermore, administration of a MALAT1 inhibitor or an miR-92a-3p mimic reduced the MICA/B shedding and enhanced recognition and killing by NK cells.	mica	85-89	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	33-39
35309907-9	2022	These results confirmed that low-dose chemotherapy induces senescence in neuroblastoma cells, and that senescent tumor cells promote the shedding of the NKG2D ligand MICA/B through the MALAT1/miR-92a/ADAM10 axis, thereby contributing to the formation of a suppressive immune microenvironment and promoting immune escape.	mica	166-170	killer cell lectin like receptor K1	Homo sapiens	153-158
35309907-9	2022	These results confirmed that low-dose chemotherapy induces senescence in neuroblastoma cells, and that senescent tumor cells promote the shedding of the NKG2D ligand MICA/B through the MALAT1/miR-92a/ADAM10 axis, thereby contributing to the formation of a suppressive immune microenvironment and promoting immune escape.	mica	166-170	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	185-191
35309907-9	2022	These results confirmed that low-dose chemotherapy induces senescence in neuroblastoma cells, and that senescent tumor cells promote the shedding of the NKG2D ligand MICA/B through the MALAT1/miR-92a/ADAM10 axis, thereby contributing to the formation of a suppressive immune microenvironment and promoting immune escape.	mica	166-170	ADAM metallopeptidase domain 10	Homo sapiens	200-206
34581579-8	2021	Finally, we discovered that intracellular MICA-glutathione metabolites are recognized and exported by the efflux pump MRP1, providing a parallel and perhaps complementary pathway for MGO detoxification working alongside the glyoxalase pathway.	mica	42-46	ATP binding cassette subfamily C member 1	Homo sapiens	118-122
35119498-9	2022	Importantly, EVs from cytokine-stimulated NK cells penetrate into the spheroid core, and tumor spheroid susceptibility to NK-cell derived EVs was linked to differential expression of the NKG2D ligands MICA/B, which was blocked with an anti-NKG2D antibody.	mica	201-205	killer cell lectin like receptor K1	Homo sapiens	240-245
35154904-1	2022	DNA damage by genotoxic drugs such as gemcitabine and 5-fluorouracil (5-FU) activates the ataxia telangiectasia, mutated (ATM)-Chk pathway and induces the expression of NKG2D ligands such as the MHC class I-related chain A and B (MICA/B).	mica	230-234	ataxia telangiectasia mutated	Mus musculus	122-125
35154904-1	2022	DNA damage by genotoxic drugs such as gemcitabine and 5-fluorouracil (5-FU) activates the ataxia telangiectasia, mutated (ATM)-Chk pathway and induces the expression of NKG2D ligands such as the MHC class I-related chain A and B (MICA/B).	mica	230-234	megakaryocyte-associated tyrosine kinase	Mus musculus	127-130
35154904-1	2022	DNA damage by genotoxic drugs such as gemcitabine and 5-fluorouracil (5-FU) activates the ataxia telangiectasia, mutated (ATM)-Chk pathway and induces the expression of NKG2D ligands such as the MHC class I-related chain A and B (MICA/B).	mica	230-234	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	169-174
6512859-4	1984	Significant differences were observed depending on whether the electron microscope specimens were prepared by spraying or by layering of the titin onto a mica substrate; we tentatively attribute these differences to elasticity in the titin, revealed by the high shearing forces that accompany spraying.	mica	154-158	titin	Homo sapiens	141-146
6417145-7	1983	In contrast, fibronectin molecules sprayed onto mica surfaces at pH 7, rotary shadowed, and examined by transmission electron microscopy were elongated and nodular with a contour length of 120-130 nm.	mica	48-52	fibronectin 1	Homo sapiens	13-24
11596491-1	1983	The mica replication technique first described by Hall [5] has produced myosin molecules which were heterogeneous in appearance in terms of shadowing, decoration, contrast and background.	mica	4-8	myosin heavy chain 14	Homo sapiens	72-78
960051-0	1976	Fibrinogen structure after spraying on mica: assessing the electron microscopic basis for a trinodular model.	mica	39-43	fibrinogen beta chain	Homo sapiens	0-10
870006-1	1977	A mica adsorption technique was used to prepare fibrinogen and early fibrin polymers for examination in the transmission electron microscope.	mica	2-6	fibrinogen beta chain	Homo sapiens	48-58
4327023-1	1971	I. Competetive adsorption of fibrinogen and heparin on mica.	mica	55-59	fibrinogen beta chain	Homo sapiens	29-39
33789714-8	2021	RESULTS: Here we show that MITF regulates expression of ADAM10, a key sheddase that cleaves the MICA/B family of ligands for NK cells.	mica	96-100	melanogenesis associated transcription factor	Mus musculus	27-31
33368266-6	2021	Finally, knocking down of HEIH resulted in improvement of immunogenic profile of TNBC cells through inducing MICA/B and suppressing the immune checkpoint inhibitor PDL1.	mica	109-113	hepatocellular carcinoma up-regulated EZH2-associated long non-coding RNA	Homo sapiens	26-30
33713674-5	2021	In AFM experiments, both Dps protein molecules and DNA-Dps complexes adsorbed on mica or highly oriented pyrolytic graphite (HOPG) surfaces form densely packed hexagonal structures with a characteristic size of about 9 nm.	mica	81-85	decaprenyl diphosphate synthase subunit 1	Homo sapiens	25-28
33713674-5	2021	In AFM experiments, both Dps protein molecules and DNA-Dps complexes adsorbed on mica or highly oriented pyrolytic graphite (HOPG) surfaces form densely packed hexagonal structures with a characteristic size of about 9 nm.	mica	81-85	decaprenyl diphosphate synthase subunit 1	Homo sapiens	55-58
33789714-8	2021	RESULTS: Here we show that MITF regulates expression of ADAM10, a key sheddase that cleaves the MICA/B family of ligands for NK cells.	mica	96-100	a disintegrin and metallopeptidase domain 10	Mus musculus	56-62
31661135-10	2019	NRF2-dependent upregulation of the NKG2D ligand MICA/B was observed.	mica	48-52	NFE2 like bZIP transcription factor 2	Homo sapiens	0-4
33440654-0	2021	ADCC against MICA/B Is Mediated against Differentiated Oral and Pancreatic and Not Stem-Like/Poorly Differentiated Tumors by the NK Cells; Loss in Cancer Patients due to Down-Modulation of CD16 Receptor.	mica	13-17	Fc gamma receptor IIIa	Homo sapiens	189-193
32636849-14	2020	This appeared to be at least in part due to an inverse correlation between NODAL and surface MICA/B expression on breast cancer target lines.	mica	93-97	nodal growth differentiation factor	Homo sapiens	75-80
31348857-3	2019	The morphology of PEO layers (adsorbed onto mica), to which liposomes were added, was examined using atomic force microscopy (AFM) and cryo-scanning electron microscopy (cryo-SEM).	mica	44-48	twinkle mtDNA helicase	Homo sapiens	18-21
31348857-7	2019	Remarkably, such bridging could be suppressed and the friction could be restored to its previous low value if the KNO3 was replaced with NaNO3, as a result of the different PEO-mica ligation properties of Na+ compared to those of K+.	mica	177-181	twinkle mtDNA helicase	Homo sapiens	173-176
31355643-10	2019	In addition, this study finds exceptionally poor LUB adhesion to both mica and poly(methyl methacrylate) surfaces that remain widely used substrates for constructing model surfaces in fundamental tribology studies which may have significant implications for the findings of a number of foundational studies into LUB tribology and molecular synergies.	mica	70-74	proteoglycan 4	Homo sapiens	49-52
33266137-0	2020	An Anti-MICA/B Antibody and IL-15 Rescue Altered NKG2D-Dependent NK Cell Responses in Hepatocellular Carcinoma.	mica	8-12	killer cell lectin like receptor K1	Homo sapiens	49-54
33266137-10	2020	Anti-MICA/B mAb associated with IL-15 was able to induce PB NK cytotoxicity for primary HCC cells in HD and patients with HCC, who also showed NK-TIL degranulation for autologous primary HCC cells.	mica	5-9	interleukin 15	Homo sapiens	32-37
33266137-11	2020	Our findings highlight the key role of the NKG2D-MICA/B axis in the regulation of NK cell responses in HCC and provide evidence in support of a potentially important role of anti-MICA/B mAb and IL-15 stimulation in HCC immunotherapy.	mica	49-53	killer cell lectin like receptor K1	Homo sapiens	43-48
33010307-3	2020	An archaeal single-subunit OST protein was immobilized on a mica support via biotin-avidin interactions and reconstituted in a lipid bilayer.	mica	60-64	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	27-30
32996653-4	2020	Here, we demonstrate that the SCFA propionate upregulates surface expression of the immune stimulatory NKG2D ligands, MICA/B by imposing metabolic changes in dividing cells.	mica	118-122	killer cell lectin like receptor K1	Homo sapiens	103-108
32996653-6	2020	By siRNA-directed knockdown, we could further link phosphoenolpyruvate carboxykinase (PEPCK), the rate-limiting enzyme in gluconeogenesis to propionate regulation of MICA/B expression.	mica	166-170	phosphoenolpyruvate carboxykinase 2, mitochondrial	Homo sapiens	51-84
32996653-6	2020	By siRNA-directed knockdown, we could further link phosphoenolpyruvate carboxykinase (PEPCK), the rate-limiting enzyme in gluconeogenesis to propionate regulation of MICA/B expression.	mica	166-170	phosphoenolpyruvate carboxykinase 2, mitochondrial	Homo sapiens	86-91
32996653-7	2020	Moreover, knockdown of Rictor and specific mTOR inhibitors implicated mTORC2 activity with metabolic changes that control MICA/B expression.	mica	122-126	RPTOR independent companion of MTOR complex 2	Homo sapiens	23-29
32996653-7	2020	Moreover, knockdown of Rictor and specific mTOR inhibitors implicated mTORC2 activity with metabolic changes that control MICA/B expression.	mica	122-126	mechanistic target of rapamycin kinase	Homo sapiens	43-47
31661135-10	2019	NRF2-dependent upregulation of the NKG2D ligand MICA/B was observed.	mica	48-52	killer cell lectin like receptor K1	Homo sapiens	35-40
31088566-0	2019	High glucose promotes pancreatic cancer cells to escape from immune surveillance via AMPK-Bmi1-GATA2-MICA/B pathway.	mica	101-105	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	85-89
31181466-2	2019	A two-dimensional network of DNA structures was successfully stretched on Mg2+-modified mica substrates under a DC electric field (1 V, 1 A) and imaged in gaseous and aqueous phases by atomic force microscopy.	mica	88-92	mucin 7, secreted	Homo sapiens	74-77
31427976-0	2019	Small Intestine Protection of Mica Against Non-Steroidal Anti-Inflammatory Drugs-Injury Through ERK1/2 Signal Pathway in Rats.	mica	30-34	mitogen activated protein kinase 3	Rattus norvegicus	96-102
31427976-16	2019	Tryptase, PAR-2, and p-ERK1/2 expression was down-regulated in mica group compared with model group.	mica	63-67	tryptase alpha/beta 1	Rattus norvegicus	0-8
31427976-16	2019	Tryptase, PAR-2, and p-ERK1/2 expression was down-regulated in mica group compared with model group.	mica	63-67	F2R like trypsin receptor 1	Rattus norvegicus	10-15
31427976-16	2019	Tryptase, PAR-2, and p-ERK1/2 expression was down-regulated in mica group compared with model group.	mica	63-67	mitogen activated protein kinase 3	Rattus norvegicus	23-29
31427976-17	2019	Conclusion: Mica inhibit small intestinal injury induced by NSAIDs via ERK signaling pathway.	mica	12-16	mitogen activated protein kinase 3	Rattus norvegicus	71-74
31088566-9	2019	Bmi1, a polycomb group (PcG) protein, was found to be up-regulated by high glucose, and mediated the inhibition of MICA/B expression through promoting GATA2 in pancreatic cancer.	mica	115-119	BMI1 proto-oncogene, polycomb ring finger	Homo sapiens	0-4
31088566-12	2019	In this process, constitutive activation of AMPK-Bmi1-GATA2 axis could mediate MICA/B inhibition, which may serve as a therapeutic target for further intervention of pancreatic cancer immune evasion.	mica	79-83	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	44-48
31088566-12	2019	In this process, constitutive activation of AMPK-Bmi1-GATA2 axis could mediate MICA/B inhibition, which may serve as a therapeutic target for further intervention of pancreatic cancer immune evasion.	mica	79-83	BMI1 proto-oncogene, polycomb ring finger	Homo sapiens	49-53
31033991-10	2019	The resulting radiotracer, [18F]MICA-302, showed good labeling of active caspase-3 in vitro and favorable pharmacokinetic properties.	mica	32-36	caspase 3	Homo sapiens	73-82
31088566-0	2019	High glucose promotes pancreatic cancer cells to escape from immune surveillance via AMPK-Bmi1-GATA2-MICA/B pathway.	mica	101-105	GATA binding protein 2	Homo sapiens	95-100
31088566-12	2019	In this process, constitutive activation of AMPK-Bmi1-GATA2 axis could mediate MICA/B inhibition, which may serve as a therapeutic target for further intervention of pancreatic cancer immune evasion.	mica	79-83	GATA binding protein 2	Homo sapiens	54-59
30667553-4	2019	Crystals of insulin were epitaxially grown on the template, whereas insulin crystals grown on clean muscovite mica had a random orientation.	mica	110-114	insulin	Homo sapiens	68-75
30901531-4	2019	Compared to on the hydrophilic mica surface, FVIII proteins appear bigger vertical sizes while similar lateral sizes on the HOPG surface.	mica	31-35	coagulation factor VIII	Homo sapiens	45-50
30327650-7	2018	UL142, ectopically expressed in isolation, and UL148A, target specific MICA allotypes that are ligands for NKG2D.	mica	71-75	killer cell lectin like receptor K1	Homo sapiens	107-112
30845699-2	2019	Most gammadelta-T-cells become activated via a major histocompatibility complex (MHC)-independent pathway by the interaction of their receptor, Natural Killer Group 2 Member D (NKG2D) with the tumor-specific NKG2D ligands, including MHC class I-related chain A/B (MICA/B) and UL16-binding proteins (ULBPs), to kill tumor cells.	mica	264-268	killer cell lectin like receptor K1	Homo sapiens	144-175
30845699-2	2019	Most gammadelta-T-cells become activated via a major histocompatibility complex (MHC)-independent pathway by the interaction of their receptor, Natural Killer Group 2 Member D (NKG2D) with the tumor-specific NKG2D ligands, including MHC class I-related chain A/B (MICA/B) and UL16-binding proteins (ULBPs), to kill tumor cells.	mica	264-268	killer cell lectin like receptor K1	Homo sapiens	177-182
30676017-3	2019	In this work, ammonium polyphosphate/zinc borate (APP/ZB) was developed to achieve the highly efficient flame retardance and ceramization of the ethylene-vinyl acetate/mica powder/organo-modified montmorillonite (EVA/MP/OMMT) composite.	mica	168-172	amyloid beta precursor protein	Homo sapiens	50-56
30676017-3	2019	In this work, ammonium polyphosphate/zinc borate (APP/ZB) was developed to achieve the highly efficient flame retardance and ceramization of the ethylene-vinyl acetate/mica powder/organo-modified montmorillonite (EVA/MP/OMMT) composite.	mica	168-172	myelin protein zero like 2	Homo sapiens	213-216
30608145-3	2019	In this work, the adsorption behavior and lubrication mechanism of full-length recombinant human PRG4 (rhPRG4) on mica as well as the effect of adding hyaluronic acid (HA, a polysaccharide) were systematically investigated using a surface forces apparatus (SFA) technique.	mica	114-118	proteoglycan 4	Homo sapiens	97-101
30056470-5	2018	Hyperglycemia and tau phosphorylation were induced by either RNAi suppression of the dld-1 gene or by inhibition of the DLD enzyme by the inhibitor, 2-methoxyindole-2-carboxylic acid (MICA).	mica	184-188	microtubule associated protein tau	Homo sapiens	18-21
30056470-7	2018	While inhibition of the dld-1 gene or treatment with MICA partially reversed the inhibition of acetylcholine neurotransmission by tau, neither treatment affected tau inhibited mobility.	mica	53-57	microtubule associated protein tau	Homo sapiens	130-133
30001104-6	2018	The monomers were induced into monolayers when the F-SAP solution in HFIP was adsorbed on mica as observed by atomic force microscopy.	mica	90-94	hyaluronan binding protein 2	Homo sapiens	51-56
29793174-0	2018	Effect of Ca2+ ion concentration on adsorption of poly(carboxylate ether)-based (PCE) superplasticizer on mica.	mica	106-110	carbonic anhydrase 2	Homo sapiens	10-13
29741244-5	2018	In line with this suggestion, we studied NK cell cytotoxicity in peripheral blood of PE patients and controls and the mRNA expression of cytokines and of the NKG2D receptor and its ligands MICA/B and ULBP1-3 in PE- and normal placenta.	mica	189-193	killer cell lectin like receptor K1	Homo sapiens	158-172
29741244-7	2018	The cytokine mRNA profiles and the mRNA expression of the NKG2D receptor and its ligands MICA/B and ULBP 1-3 in PE placenta were assessed and compared to those in normal placenta using real-time quantitative RT-PCR.	mica	89-93	killer cell lectin like receptor K1	Homo sapiens	58-72
30307208-0	2018	Structure and dynamics of mica-confined films of [C10C1Pyrr][NTf2] ionic liquid.	mica	26-30	nuclear transport factor 2	Homo sapiens	61-65
29379285-4	2018	The formation of a single p53-COP1 bimolecular complex was visualized by atomic force microscopy imaging on a mica substrate.	mica	110-114	tumor protein p53	Homo sapiens	26-29
29394917-7	2018	RESULTS: Compared to pure DCIS, miCa contained significantly more cases with TIL density grade 3 (p = 0.028).	mica	32-36	toll like receptor 1	Homo sapiens	77-80
29394917-8	2018	Concordantly, CD8+, CD4+ and CD38+ cells were more numerous in miCa than in pure DCIS.	mica	63-67	CD8a molecule	Homo sapiens	14-17
29394917-8	2018	Concordantly, CD8+, CD4+ and CD38+ cells were more numerous in miCa than in pure DCIS.	mica	63-67	CD4 molecule	Homo sapiens	20-23
29394917-8	2018	Concordantly, CD8+, CD4+ and CD38+ cells were more numerous in miCa than in pure DCIS.	mica	63-67	CD38 molecule	Homo sapiens	29-33
29394917-13	2018	CONCLUSION: Results indicate that TIL density level can distinguish 2 biologically different DCIS subgroups, one of which (DCIS with >=30% TILs, the TIL-rich DCIS) is like miCa.	mica	175-179	toll like receptor 1	Homo sapiens	34-37
29394917-13	2018	CONCLUSION: Results indicate that TIL density level can distinguish 2 biologically different DCIS subgroups, one of which (DCIS with >=30% TILs, the TIL-rich DCIS) is like miCa.	mica	175-179	toll like receptor 1	Homo sapiens	142-145
29101877-1	2018	The aim of this work was to assess for the first time the use of two high-charge swelling micas (Na-Mica-4 and C18-Mica-4) for the removal of four linear alkylbenzene sulfonates (LAS) from aqueous samples.	mica	90-95	MHC class I polypeptide-related sequence A	Homo sapiens	115-119
29555675-0	2018	NKG2D-MICA Interaction: A Paradigm Shift in Innate Recognition.	mica	6-10	killer cell lectin like receptor K1	Homo sapiens	0-5
29101877-1	2018	The aim of this work was to assess for the first time the use of two high-charge swelling micas (Na-Mica-4 and C18-Mica-4) for the removal of four linear alkylbenzene sulfonates (LAS) from aqueous samples.	mica	90-95	MHC class I polypeptide-related sequence A	Homo sapiens	100-104
29101877-1	2018	The aim of this work was to assess for the first time the use of two high-charge swelling micas (Na-Mica-4 and C18-Mica-4) for the removal of four linear alkylbenzene sulfonates (LAS) from aqueous samples.	mica	90-95	Bardet-Biedl syndrome 9	Homo sapiens	111-114
29379285-4	2018	The formation of a single p53-COP1 bimolecular complex was visualized by atomic force microscopy imaging on a mica substrate.	mica	110-114	COP1 E3 ubiquitin ligase	Homo sapiens	30-34
28701757-6	2017	First, MV-Edm infection compelled HCC cells to express the specific NKG2D ligands MICA/B, which may contribute to the activation of CD8+NKG2D+ cells.	mica	82-86	killer cell lectin like receptor K1	Homo sapiens	68-73
29078994-0	2018	Sup35NMp morphology evaluation on Au, Si, formvar and mica surfaces using AFM, SEM and TEM.	mica	54-58	translation termination factor GTPase eRF3	Saccharomyces cerevisiae S288C	0-8
29078994-3	2018	Here, we consider one of the first amyloids found in Saccharomyces cerevisiae yeast, i.e. Sup35NMp, to study the adsorption of monomeric protein and its fibrils on the surface of mica, silica, gold and on formvar film.	mica	179-183	translation termination factor GTPase eRF3	Saccharomyces cerevisiae S288C	90-98
29055493-12	2017	Results of polycations (PEI, PAMAM dendrimers, PAH, PDADMAC) and polyanions (PAA, PSS) adsorption on mica, silicon, gold, and PTFE are quantitatively interpreted in terms of theoretical approaches postulating the three dimensional charge distribution or the random sequential adsorption model (RSA).	mica	101-105	PSS	Homo sapiens	82-85
28825842-1	2017	Bulk physicochemical properties of neurotrophin 4 (NT-4) in electrolyte solutions and its adsorption/desorption on/from mica surfaces have been studied using dynamic light scattering (DLS), microelectrophoresis, a solution depletion technique (enzyme-linked immunosorbent assay, ELISA), and AFM imaging.	mica	15-19	neurotrophin 4	Homo sapiens	35-49
28825842-1	2017	Bulk physicochemical properties of neurotrophin 4 (NT-4) in electrolyte solutions and its adsorption/desorption on/from mica surfaces have been studied using dynamic light scattering (DLS), microelectrophoresis, a solution depletion technique (enzyme-linked immunosorbent assay, ELISA), and AFM imaging.	mica	15-19	neurotrophin 4	Homo sapiens	51-55
28623696-6	2017	MIM protein with two different sizes were observed on mica surface with AFM.	mica	54-58	MTSS I-BAR domain containing 1	Homo sapiens	0-3
28722103-0	2017	Decreased levels of active uPA and KLK8 assessed by [111 In]MICA-401 binding correlate with the seizure burden in an animal model of temporal lobe epilepsy.	mica	60-64	plasminogen activator, urokinase	Rattus norvegicus	27-30
28722103-0	2017	Decreased levels of active uPA and KLK8 assessed by [111 In]MICA-401 binding correlate with the seizure burden in an animal model of temporal lobe epilepsy.	mica	60-64	kallikrein related-peptidase 8	Rattus norvegicus	35-39
28722103-7	2017	RESULTS: At 7 days post-SE, in vitro autoradiography revealed significantly decreased [111 In]MICA-401 binding in hippocampal CA3 subfield and extrahippocampal temporal lobe (ETL).	mica	94-98	carbonic anhydrase 3	Rattus norvegicus	126-129
28722103-12	2017	SIGNIFICANCE: Strong association of reduced [111 In]MICA-401 binding with seizure burden in the KASE model suggests that analysis of reduced levels of active uPA/KLK8 represents a novel biomarker candidate to be explored as a biomarker for epilepsy severity.	mica	52-56	plasminogen activator, urokinase	Rattus norvegicus	158-161
28722103-12	2017	SIGNIFICANCE: Strong association of reduced [111 In]MICA-401 binding with seizure burden in the KASE model suggests that analysis of reduced levels of active uPA/KLK8 represents a novel biomarker candidate to be explored as a biomarker for epilepsy severity.	mica	52-56	kallikrein related-peptidase 8	Rattus norvegicus	162-166
28820526-3	2017	Silica nanoparticle monolayers of controlled coverage were formed on macroion (PAH)-modified mica.	mica	93-97	phenylalanine hydroxylase	Homo sapiens	79-82
28677817-4	2017	The upregulation of major histocompatibility complex class I-related chain A and B (MICA/B) (members of NKG2D ligands) expression after DNA damage is associated with NK cell-mediated killing of cancer cells.	mica	84-88	killer cell lectin like receptor K1	Homo sapiens	104-109
28677817-7	2017	Screening in terms of chromatin remodeling identified that inhibitors related to chromatin relaxation via post-translational modification on histone H3K9, i.e. HDAC, Suv39 or G9a inhibition, restored DNA damage-dependent MICA/B expression in insensitive cells.	mica	221-225	euchromatic histone lysine methyltransferase 2	Homo sapiens	175-178
28677817-8	2017	In addition, we revealed that the restored MICA/B expression was dependent on ATR as well as E2F1, a transcription factor.	mica	43-47	ATR serine/threonine kinase	Homo sapiens	78-81
28677817-8	2017	In addition, we revealed that the restored MICA/B expression was dependent on ATR as well as E2F1, a transcription factor.	mica	43-47	E2F transcription factor 1	Homo sapiens	93-97
28677817-11	2017	Thus, the present study revealed that DNA damage-dependent MICA/B expression in insensitive cancer cells can be restored by chromatin relaxation via the HDAC/Suv39/G9a pathway.	mica	59-63	euchromatic histone lysine methyltransferase 2	Homo sapiens	164-167
28701757-6	2017	First, MV-Edm infection compelled HCC cells to express the specific NKG2D ligands MICA/B, which may contribute to the activation of CD8+NKG2D+ cells.	mica	82-86	CD8a molecule	Homo sapiens	132-135
28701757-6	2017	First, MV-Edm infection compelled HCC cells to express the specific NKG2D ligands MICA/B, which may contribute to the activation of CD8+NKG2D+ cells.	mica	82-86	killer cell lectin like receptor K1	Homo sapiens	136-141
28559451-1	2017	NKG2D (natural killer group 2, member D) is an activating receptor found on the surface of immune cells, including natural killer (NK) cells, which regulates innate and adaptive immunity through recognition of the stress-induced ligands ULBP1 (UL16 binding protein 1) to ULBP6 and MICA/B.	mica	281-285	killer cell lectin like receptor K1	Homo sapiens	0-5
28433635-1	2017	NKG2D, an activating receptor expressed on CD8+ T lymphocytes, serves as a co-stimulation molecule by engagement with its ligands MICA/B and ULBPs to trigger immune activation against tumors.	mica	130-134	killer cell lectin like receptor K1	Homo sapiens	0-5
28702455-4	2017	Our surface forces apparatus (SFA) normal force measurements indicate that the lubricin-mimetic (mimLUB) could be kept anchored between mica surfaces, even under high contact pressures, when an intermediate layer of FN was present.	mica	136-140	proteoglycan 4	Homo sapiens	79-87
28702455-6	2017	These results demonstrate synergistic interactions between mimLUB and FN in assisting the lubrication and wear protection of ideal (mica) substrates upon shear.	mica	132-136	fibronectin 1	Homo sapiens	70-72
28932644-7	2017	We also demonstrated that romidpesin significantly induced the expression of Natural Killer Group 2, Member D (NKG2D) ligands MICA/B in both rituximab-sensitive and -resistant BL cells (P < 0.001) resulting in enhancement of exPBNK in vitro cytotoxicity through NKG2D.	mica	126-130	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	111-116
28559451-1	2017	NKG2D (natural killer group 2, member D) is an activating receptor found on the surface of immune cells, including natural killer (NK) cells, which regulates innate and adaptive immunity through recognition of the stress-induced ligands ULBP1 (UL16 binding protein 1) to ULBP6 and MICA/B.	mica	281-285	UL16 binding protein 1	Homo sapiens	237-242
28559451-1	2017	NKG2D (natural killer group 2, member D) is an activating receptor found on the surface of immune cells, including natural killer (NK) cells, which regulates innate and adaptive immunity through recognition of the stress-induced ligands ULBP1 (UL16 binding protein 1) to ULBP6 and MICA/B.	mica	281-285	UL16 binding protein 1	Homo sapiens	244-266
28559451-1	2017	NKG2D (natural killer group 2, member D) is an activating receptor found on the surface of immune cells, including natural killer (NK) cells, which regulates innate and adaptive immunity through recognition of the stress-induced ligands ULBP1 (UL16 binding protein 1) to ULBP6 and MICA/B.	mica	281-285	retinoic acid early transcript 1L	Homo sapiens	271-276
28177768-0	2017	Ethanol-dependent expression of the NKG2D ligands MICA/B in human cell lines and leukocytes.	mica	50-54	killer cell lectin like receptor K1	Homo sapiens	36-41
28177768-3	2017	We hypothesized that ethanol may influence the expression of MICA and MICB, stress-induced molecules capable of regulating the activity of cytotoxic lymphocytes through the interaction with receptor NKG2D, which substantially affects the functionality of cellular immunity.	mica	61-65	killer cell lectin like receptor K1	Homo sapiens	199-204
28177768-11	2017	Presumably, changes in MICA/B expression caused by ethanol can affect the functions of NKG2D-positive cytotoxic lymphocytes, modulating immune reactions at excessive alcohol consumption.	mica	23-27	killer cell lectin like receptor K1	Homo sapiens	87-92
28423623-5	2017	This secretion reduces the expression of the two NKG2D ligands, MICA/B, at the surface of tumor cells and consequently decreases the NKG2D-dependent cytotoxic activity of NK cells against melanoma tumor cells.	mica	64-68	killer cell lectin like receptor K1	Homo sapiens	49-54
28279834-5	2017	METHODS: Here, atomic force microscopy (AFM) was used to in situ visualize the organization of apoA-I, which was exposed via depletion of the lipid component of plasma HDL pre-immobilized on functionalized mica sheets.	mica	206-210	apolipoprotein A1	Homo sapiens	95-101
28073045-5	2017	Interestingly, Bp2 that contains both hydrophobic and protonated amine units exhibits asymmetric bridging with an exceptionally high adhesion energy up to 100mJ/m2 between mica and both gold and CH3 SAM.	mica	172-176	BP2	Homo sapiens	15-18
28423623-5	2017	This secretion reduces the expression of the two NKG2D ligands, MICA/B, at the surface of tumor cells and consequently decreases the NKG2D-dependent cytotoxic activity of NK cells against melanoma tumor cells.	mica	64-68	killer cell lectin like receptor K1	Homo sapiens	133-138
28413816-8	2017	This data description also documents the coverage of solid-supported bilayers prepared by spin-coating mica using binary lipid mixes, a necessary step to ensure that AFM is performed on areas that are covered by lipid bilayers when performing experiments.	mica	103-107	afamin	Homo sapiens	166-169
28413816-10	2017	We tested naked mica s ability to cause aggregation as seen by AFM, and found this to be low compared to preparations containing negatively charged lipids.	mica	16-20	afamin	Homo sapiens	63-66
28245380-5	2017	The apoptosis induced by allo-NK cells in LSC and the expressions of NKG2D ligands including MICA/B and ULBP1-3 on LSC were detected by flow cytometry.	mica	93-97	killer cell lectin like receptor K1	Homo sapiens	69-74
28031333-5	2017	NKG2D+NK cells were also increased and preferentially activated in the HBV-infected liver (p < 0.001), in direct proportion to the percentage of MICA/B-expressing CD4 T cells colocated within freshly isolated liver tissue (p < 0.001).	mica	148-152	killer cell lectin like receptor K1	Homo sapiens	0-5
28031333-6	2017	This suggests that NKG2DL induced on T cells within a diseased organ can calibrate NKG2D-dependent activation of local NK cells; furthermore, NKG2D blockade could rescue HBV-specific and MICA/B-expressing T cells from HBV-infected livers.	mica	187-191	killer cell lectin like receptor K1	Homo sapiens	19-24
28031333-6	2017	This suggests that NKG2DL induced on T cells within a diseased organ can calibrate NKG2D-dependent activation of local NK cells; furthermore, NKG2D blockade could rescue HBV-specific and MICA/B-expressing T cells from HBV-infected livers.	mica	187-191	killer cell lectin like receptor K1	Homo sapiens	83-88
27477692-5	2017	Loss of CBP/p300 decreased the basal cell surface expression of human ligands and reduced the upregulation of MICA/B and ULBP2 in response to histone deacetylase inhibitors or DNA damage.	mica	110-114	CREB binding protein	Homo sapiens	8-16
27558262-0	2016	Preclinical evaluation of [111 In]MICA-401, an activity-based probe for SPECT imaging of in vivo uPA activity.	mica	34-38	plasminogen activator, urokinase	Mus musculus	97-100
27868339-7	2017	An interaction of the MicA stress ligand with the NKG2D receptor is necessary for the release of this cytotoxic complex.	mica	22-26	killer cell lectin like receptor K1	Homo sapiens	50-64
27558262-4	2016	A DOTA-conjugated uPA inhibitor was synthesized and radiolabelled with 111 In ([111 In]MICA-401), together with its inactive, hydrolysed form ([111 In]MICA-402).	mica	87-91	plasminogen activator, urokinase	Mus musculus	18-21
27558262-4	2016	A DOTA-conjugated uPA inhibitor was synthesized and radiolabelled with 111 In ([111 In]MICA-401), together with its inactive, hydrolysed form ([111 In]MICA-402).	mica	151-155	plasminogen activator, urokinase	Mus musculus	18-21
26940474-1	2016	MHC class I chain-related molecule A and B (MICA/B) are NK group 2 member D (NKG2D) ligands, which are broadly expressed in transformed cells.	mica	44-48	killer cell lectin like receptor K1	Homo sapiens	56-75
27468621-7	2016	The over-expression rate of MICA/B protein in the group with mutant epidermal growth factor receptor (EGFR) gene was significantly higher than that in the group with wild EGFR gene (93.8% vs 11.8%, P<0.001).	mica	28-32	epidermal growth factor receptor	Homo sapiens	68-100
27468621-7	2016	The over-expression rate of MICA/B protein in the group with mutant epidermal growth factor receptor (EGFR) gene was significantly higher than that in the group with wild EGFR gene (93.8% vs 11.8%, P<0.001).	mica	28-32	epidermal growth factor receptor	Homo sapiens	102-106
27468621-7	2016	The over-expression rate of MICA/B protein in the group with mutant epidermal growth factor receptor (EGFR) gene was significantly higher than that in the group with wild EGFR gene (93.8% vs 11.8%, P<0.001).	mica	28-32	epidermal growth factor receptor	Homo sapiens	171-175
27468621-10	2016	CONCLUSION: Overexpression of MICA/B in operable lung adenocarcinoma tissue is closely related to the mutations of EGFR and overall survival, which may be a poor prognosis indicator in patients with operable lung adenocarcinoma.	mica	30-34	epidermal growth factor receptor	Homo sapiens	115-119
27175912-3	2016	The present study demonstrated that natural killer group 2, member D (NKG2D)-major histocompatibility complex class I-related chain A/B (MICA/B) interactions contributed to the cytotoxic effect of NK cells on K562 and U251 cells.	mica	137-141	killer cell lectin like receptor K1	Homo sapiens	70-75
27633040-5	2016	Furthermore, reverse transcription polymerase chain reaction (RT-PCR), western blotting and immunofluorescence results demonstrated TMP upregulation of the expression of NKG2D ligands (NKG2DLs) MHC class I chain-related molecules A and B (MICA/B) and epithelial cell expression marker of E-cadherin, and downregulation of mesenchymal cell expression markers of vimentin and fibronectin.	mica	239-243	killer cell lectin like receptor K1	Homo sapiens	170-175
27633040-7	2016	The binding of NKG2D to its ligands activates NK cells, giving the rationale for studies on the utilization of TMP as a potential cancer therapeutic compound to increase NK cells-mediated cytotoxicity against high MICA/B expression in cancer cells.	mica	214-218	killer cell lectin like receptor K1	Homo sapiens	15-20
27494876-1	2016	MICA/B (the major histocompatibility antigen-related chain A and B) and Rae I are stress-inducible ligands for the immune-receptor NKG2D.	mica	0-4	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	131-136
27494876-3	2016	Here, we report that inhibition of xanthine oxidoreductase (XOR) activity by allopurinol or inhibition of XOR expression by gene knockdown abrogated genotoxic stress-induced expression of MICA/B and Rae I in three tumor cell lines.	mica	188-192	xanthine dehydrogenase	Mus musculus	35-58
27494876-3	2016	Here, we report that inhibition of xanthine oxidoreductase (XOR) activity by allopurinol or inhibition of XOR expression by gene knockdown abrogated genotoxic stress-induced expression of MICA/B and Rae I in three tumor cell lines.	mica	188-192	xanthine dehydrogenase	Mus musculus	60-63
27494876-3	2016	Here, we report that inhibition of xanthine oxidoreductase (XOR) activity by allopurinol or inhibition of XOR expression by gene knockdown abrogated genotoxic stress-induced expression of MICA/B and Rae I in three tumor cell lines.	mica	188-192	xanthine dehydrogenase	Mus musculus	106-109
27376848-2	2016	Here, a method is developed to design orientation-controlled and well-defined single-crystalline PbS nanoplates arrays on mica.	mica	122-126	cholinergic receptor muscarinic 3	Homo sapiens	97-100
26990637-2	2016	Oriented growth of mid-infrared Pb1- x Snx Te nanowire arrays on bendable mica, extending the function of existing nanowire arrays, is reported.	mica	74-78	polybromo 1	Homo sapiens	32-35
26940474-1	2016	MHC class I chain-related molecule A and B (MICA/B) are NK group 2 member D (NKG2D) ligands, which are broadly expressed in transformed cells.	mica	44-48	killer cell lectin like receptor K1	Homo sapiens	77-82
26940474-9	2016	In vitro assays using cell lines revealed that MICA/B expression was upregulated by cisplatin via ATM-ATR signaling, resulting in enhanced NK cell-mediated cytotoxicity.	mica	47-51	ATM serine/threonine kinase	Homo sapiens	98-101
26585323-0	2016	The MICA-129Met/Val dimorphism affects plasma membrane expression and shedding of the NKG2D ligand MICA.	mica	4-8	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	86-91
26563374-5	2016	Our results show that EOC exosomes differentially and constitutively express NKG2D ligands from both MICA/B and ULBP families on their surface, while DNAM-1 ligands are more seldom expressed and not associated with the exosomal membrane surface.	mica	101-105	killer cell lectin like receptor K1	Homo sapiens	77-82
26608587-4	2016	We therefore investigated the expression of the NKG2D receptor and its ligands MHC class I chain-related proteins A and B (MICA/B), unique long 16 binding protein (ULBP) 1, and ULBP2/5/6 in resected specimens from 82 patients with EHCC.	mica	123-127	killer cell lectin like receptor K1	Homo sapiens	48-62
26585323-0	2016	The MICA-129Met/Val dimorphism affects plasma membrane expression and shedding of the NKG2D ligand MICA.	mica	99-103	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	86-91
26585323-1	2016	The MHC class I chain-related molecule A (MICA) is a ligand for the activating natural killer (NK) cell receptor NKG2D.	mica	42-46	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	113-118
26585323-3	2016	It is known that tumors can escape NKG2D-mediated immune surveillance by proteolytic shedding of MICA.	mica	97-101	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	35-40
26585323-14	2016	Both processes appear to limit the cell surface expression of MICA-129Met variants that have a high binding avidity to NKG2D.	mica	62-66	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	119-124
26272241-1	2016	Colloid particle deposition was applied in order to characterize human serum albumin (HSA) monolayers on mica adsorbed under diffusion transport at pH 3.5.	mica	105-109	albumin	Homo sapiens	71-84
26855469-1	2016	After an hour contact with a phospholipase A2 (PLA2) solution, only the outer leaflet of the dipalmitoylphosphatidylcholine (DPPC) bilayers supported on mica surface underwent hydrolysis whose products, i.e., palmitic acid and lysophospholipid, accumulated on the bilayer surface.	mica	153-157	phospholipase A2 group IB	Homo sapiens	29-45
26613862-0	2015	Electrokinetic characteristics of HSA dimer and its monolayers at mica.	mica	66-70	albumin	Homo sapiens	34-37
26855469-1	2016	After an hour contact with a phospholipase A2 (PLA2) solution, only the outer leaflet of the dipalmitoylphosphatidylcholine (DPPC) bilayers supported on mica surface underwent hydrolysis whose products, i.e., palmitic acid and lysophospholipid, accumulated on the bilayer surface.	mica	153-157	phospholipase A2 group IB	Homo sapiens	47-51
26122035-5	2016	In addition, recent evidences suggest that HIV-1-infected CD4(+) T cells may release NKG2DLs, particularly MICA, in soluble form, a phenomenon that has the potential to down-modulate NKG2D on circulating lymphocytes and allow evasion of NKG2D-mediated immune responses.	mica	107-111	killer cell lectin like receptor K1	Homo sapiens	85-90
26122035-5	2016	In addition, recent evidences suggest that HIV-1-infected CD4(+) T cells may release NKG2DLs, particularly MICA, in soluble form, a phenomenon that has the potential to down-modulate NKG2D on circulating lymphocytes and allow evasion of NKG2D-mediated immune responses.	mica	107-111	killer cell lectin like receptor K1	Homo sapiens	183-188
26692933-6	2015	DAC up-regulated the expression of MICA/B, ULBP-1 and ULBP-3 in HL-60 cells, and increased the killing activity of NK cells to HL-60 cells.	mica	35-39	arylacetamide deacetylase	Homo sapiens	0-3
26340356-3	2015	When we perform mica-assisted growth annealing with CT1, a dramatic dimensional change occurs where the 1D nanotubes transform into 2D nanolattices due to the presence of the substrate.	mica	16-20	cardiotrophin 1	Homo sapiens	52-55
26340356-4	2015	We assessed the coverage percentage of the 2D nanolattices grown on the mica substrate with CT1 and CT2 as a function of the concentration of the DNA monomer.	mica	72-76	cardiotrophin 1	Homo sapiens	92-95
26340356-4	2015	We assessed the coverage percentage of the 2D nanolattices grown on the mica substrate with CT1 and CT2 as a function of the concentration of the DNA monomer.	mica	72-76	cancer/testis antigen 2	Homo sapiens	100-103
26439264-11	2015	Additionally, we showed that both ATM-ATR and EGFR regulate MICA/B via miR20a.	mica	60-64	ATM serine/threonine kinase	Homo sapiens	34-37
26439264-11	2015	Additionally, we showed that both ATM-ATR and EGFR regulate MICA/B via miR20a.	mica	60-64	ATR serine/threonine kinase	Homo sapiens	38-41
26439264-11	2015	Additionally, we showed that both ATM-ATR and EGFR regulate MICA/B via miR20a.	mica	60-64	epidermal growth factor receptor	Homo sapiens	46-50
26439264-11	2015	Additionally, we showed that both ATM-ATR and EGFR regulate MICA/B via miR20a.	mica	60-64	microRNA 20a	Homo sapiens	71-77
26221979-3	2015	Using a Surface Forces Apparatus, we have measured the normal (adhesion/repulsion) and lateral (friction) forces across layers of individual synovial fluid components physisorbed onto FN-coated mica substrates.	mica	194-198	fibronectin 1	Homo sapiens	184-186
26221979-4	2015	Our chief findings are (i) FN strongly tethers LUB and HA to mica, as indicated by high and reversible long-range repulsive normal interactions between surfaces, and (ii) FN and LUB synergistically enhance wear protection of surfaces during shear, as suggested by the structural robustness of FN+LUB layers under pressures up to about 4 MPa.	mica	61-65	fibronectin 1	Homo sapiens	27-29
26221979-4	2015	Our chief findings are (i) FN strongly tethers LUB and HA to mica, as indicated by high and reversible long-range repulsive normal interactions between surfaces, and (ii) FN and LUB synergistically enhance wear protection of surfaces during shear, as suggested by the structural robustness of FN+LUB layers under pressures up to about 4 MPa.	mica	61-65	proteoglycan 4	Homo sapiens	47-50
26221979-4	2015	Our chief findings are (i) FN strongly tethers LUB and HA to mica, as indicated by high and reversible long-range repulsive normal interactions between surfaces, and (ii) FN and LUB synergistically enhance wear protection of surfaces during shear, as suggested by the structural robustness of FN+LUB layers under pressures up to about 4 MPa.	mica	61-65	fibronectin 1	Homo sapiens	171-173
26221979-4	2015	Our chief findings are (i) FN strongly tethers LUB and HA to mica, as indicated by high and reversible long-range repulsive normal interactions between surfaces, and (ii) FN and LUB synergistically enhance wear protection of surfaces during shear, as suggested by the structural robustness of FN+LUB layers under pressures up to about 4 MPa.	mica	61-65	proteoglycan 4	Homo sapiens	178-181
26221979-4	2015	Our chief findings are (i) FN strongly tethers LUB and HA to mica, as indicated by high and reversible long-range repulsive normal interactions between surfaces, and (ii) FN and LUB synergistically enhance wear protection of surfaces during shear, as suggested by the structural robustness of FN+LUB layers under pressures up to about 4 MPa.	mica	61-65	fibronectin 1	Homo sapiens	171-173
26221979-4	2015	Our chief findings are (i) FN strongly tethers LUB and HA to mica, as indicated by high and reversible long-range repulsive normal interactions between surfaces, and (ii) FN and LUB synergistically enhance wear protection of surfaces during shear, as suggested by the structural robustness of FN+LUB layers under pressures up to about 4 MPa.	mica	61-65	proteoglycan 4	Homo sapiens	178-181
25866912-4	2015	An AFM tip was functionalized with ANK1-62k and used to probe spectrin crosslinked to mica surface.	mica	86-90	ankyrin 1	Homo sapiens	35-39
25982889-5	2015	Comparative height profile analysis combined with ATR-FTIR studies of the spectral regions characteristic of carboxylic groups and C1s core level envelope by XPS confirmed specific interactions between LPSQ-COOH and mica.	mica	216-220	complement C1s	Homo sapiens	131-134
25806669-6	2015	Mucin molecules adsorbed abundantly onto mica from saline buffer, generating polymer-like, long-ranged, repulsive, and nonhysteretic forces upon compression of the adsorbed layers.	mica	41-45	mucin 1, cell surface associated	Bos taurus	0-5
24997223-7	2014	Human monocyte-derived macrophages treated in vitro with acetylated low-density lipoproteins enhanced expression of MICA/B and scavenger receptor A, thus accounting for NKG2D ligand expression in foam cells infiltrating atherosclerotic plaques.	mica	116-120	killer cell lectin like receptor K1	Homo sapiens	169-174
25510288-7	2014	ULBP1 expression was correlated with MICA/B (p<0.001) and ULBP2 (p=0.002) expression in cervical cancer.	mica	37-41	UL16 binding protein 1	Homo sapiens	0-5
25510288-10	2014	Multivariate analysis indicated that MICA/B+/ULBP1+ (HR=0.16, p=0.015) and ULBP1+ (HR=0.31, p=0.024) are independent prognostic factors of disease-free survival in cervical cancer.	mica	37-41	UL16 binding protein 1	Homo sapiens	45-50
24813230-7	2014	Taken together, our data indicate that increased levels of miR-20a in tumor cells may indirectly suppress NK cell cytotoxicity by downregulating MICA/B expression.	mica	145-149	microRNA 20a	Homo sapiens	59-66
25103413-5	2015	A knockdown of HIF-1alpha revealed that the decreased surface expression of MICA/B under hypoxia is dependent on HIF-1alpha in H1339 cells with high basal HIF-1alpha levels.	mica	76-80	hypoxia inducible factor 1 subunit alpha	Homo sapiens	15-25
25103413-5	2015	A knockdown of HIF-1alpha revealed that the decreased surface expression of MICA/B under hypoxia is dependent on HIF-1alpha in H1339 cells with high basal HIF-1alpha levels.	mica	76-80	hypoxia inducible factor 1 subunit alpha	Homo sapiens	113-123
25103413-5	2015	A knockdown of HIF-1alpha revealed that the decreased surface expression of MICA/B under hypoxia is dependent on HIF-1alpha in H1339 cells with high basal HIF-1alpha levels.	mica	76-80	hypoxia inducible factor 1 subunit alpha	Homo sapiens	113-123
24813230-4	2014	We found that miR-20a binds directly to the 3"-untranslated region of MICA/B mRNA, resulting in its degradation and reducing its protein levels on the plasma membrane.	mica	70-74	microRNA 20a	Homo sapiens	14-21
24813230-5	2014	Reduction of membrane-bound MICA/B proteins, which are ligands of the natural killer group 2 member D (NKG2D) receptor found on natural killer (NK) cells, gammadelta(+) T cells and CD8(+) T cells, allows tumor cells to evade immune-mediated killing.	mica	28-32	killer cell lectin like receptor K1	Homo sapiens	70-101
24813230-5	2014	Reduction of membrane-bound MICA/B proteins, which are ligands of the natural killer group 2 member D (NKG2D) receptor found on natural killer (NK) cells, gammadelta(+) T cells and CD8(+) T cells, allows tumor cells to evade immune-mediated killing.	mica	28-32	killer cell lectin like receptor K1	Homo sapiens	103-118
24997223-6	2014	Foam cells expressing NKG2D ligands MICA/B were found in advanced atherosclerotic lesions accompanied by a large necrotic core or hemorrhage.	mica	36-40	killer cell lectin like receptor K1	Homo sapiens	22-27
24370024-2	2013	The expressions of NKG2D ligand MICA/B, ULBP1-3 in several human leukemia cell lines (K562, OUN-1, U937 and K562/AO2), as well as primary leukemic cells isolated from malignant leukemia patients were analyzed by flow cytometry.	mica	32-36	killer cell lectin like receptor K1	Homo sapiens	19-24
24455460-1	2014	Amplitude-modulation atomic force microscopy (AM-AFM) is used to determine the retention properties of CaF2 nanoparticles adsorbed on mica and on tooth enamel in liquid.	mica	134-138	CCR4-NOT transcription complex subunit 8	Homo sapiens	103-107
24718859-2	2014	One way cytolytic lymphocytes recognize tumor cells is by engagement of their activating receptor, NKG2D, by stress antigens of the MICA/B and ULBP families.	mica	132-136	killer cell lectin like receptor K1	Homo sapiens	99-104
24352446-5	2014	Reestablishment of complement protein expression was found to be mediated by direct interaction between NKG2D on NK cells and the hepatocyte protein major histocompatibility complex class I-related chains A and B (MICA/B) and not to be associated with specific cytokine signaling events.	mica	214-218	killer cell lectin like receptor K1	Homo sapiens	104-109
24354916-5	2014	The latter value matches the maximum coverage previously determined for human serum albumin on mica using the streaming potential method.	mica	95-99	albumin	Homo sapiens	78-91
23987654-4	2013	By repeated scanning of a single line on a SELP-coated mica surface, we observed a sudden stepwise height increase.	mica	55-59	selectin P	Homo sapiens	43-47
23117544-6	2013	Our results suggest that the unfolded, self-assembled Pop1 is more active in inducing defense, and that the unfolding process can be induced by interaction with hydrophobic inanimate surfaces such as Teflon, treated mica, and gold sheets.	mica	216-220	POP1 homolog, ribonuclease P/MRP subunit	Homo sapiens	54-58
23937531-1	2013	Colloid particle deposition was applied to characterize bovine and human fibrinogen (Fb) monolayers on mica produced by controlled adsorption under diffusion transport at pH 3.5.	mica	103-107	fibrinogen beta chain	Homo sapiens	73-83
23937531-1	2013	Colloid particle deposition was applied to characterize bovine and human fibrinogen (Fb) monolayers on mica produced by controlled adsorption under diffusion transport at pH 3.5.	mica	103-107	fibrinogen beta chain	Homo sapiens	85-87
23937531-4	2013	It was shown that Fb adsorbs irreversibly on mica for a broad range of ionic strength of 4 x 10(-4) to 0.15 M, NaCl.	mica	45-49	fibrinogen beta chain	Homo sapiens	18-20
23937531-5	2013	The overcharging of initially negative mica surface occurred for fibrinogen surface concentrations higher than 1400 mum(-2).	mica	39-43	fibrinogen beta chain	Homo sapiens	65-75
23937531-9	2013	This confirms that, at this pH, fibrinogen molecules adsorb end-on on mica assuming extended conformations with the positive charge located mostly in the end part of the alphaA chains.	mica	70-74	fibrinogen beta chain	Homo sapiens	32-42
23937096-0	2013	Impact of nanoscale surface heterogeneity on precursor film growth and macroscopic spreading of [Rmim][NTf2] ionic liquids on mica.	mica	126-130	nuclear transport factor 2	Homo sapiens	103-107
23820258-1	2013	BACKGROUND: NKG2D recognises several ligands, including polymorphic major histocompatibility complex class I chain-related chain-related proteins A and B (MICA/B) and unique long 16-binding proteins (ULBPs).	mica	155-159	killer cell lectin like receptor K1	Homo sapiens	12-17
23820258-11	2013	miR-302c and miR-520c expression was induced, and their levels inversely correlated with the levels of NKG2D ligands MICA/B and ULBP2 upon 1,25(OH)2D3 treatment.	mica	117-121	microRNA 302c	Homo sapiens	0-8
23820258-11	2013	miR-302c and miR-520c expression was induced, and their levels inversely correlated with the levels of NKG2D ligands MICA/B and ULBP2 upon 1,25(OH)2D3 treatment.	mica	117-121	microRNA 520c	Homo sapiens	13-21
23820258-11	2013	miR-302c and miR-520c expression was induced, and their levels inversely correlated with the levels of NKG2D ligands MICA/B and ULBP2 upon 1,25(OH)2D3 treatment.	mica	117-121	killer cell lectin like receptor K1	Homo sapiens	103-108
23820258-12	2013	A luciferase reporter assay revealed that miR-302c and miR-520c directly targeted the 3"-UTRs of MICA/B and ULBP2 and negatively regulated the expression of MIA/B and ULBP2.	mica	97-101	microRNA 302c	Homo sapiens	42-50
23820258-12	2013	A luciferase reporter assay revealed that miR-302c and miR-520c directly targeted the 3"-UTRs of MICA/B and ULBP2 and negatively regulated the expression of MIA/B and ULBP2.	mica	97-101	microRNA 520c	Homo sapiens	55-63
23820258-12	2013	A luciferase reporter assay revealed that miR-302c and miR-520c directly targeted the 3"-UTRs of MICA/B and ULBP2 and negatively regulated the expression of MIA/B and ULBP2.	mica	97-101	UL16 binding protein 2	Homo sapiens	108-113
23820258-12	2013	A luciferase reporter assay revealed that miR-302c and miR-520c directly targeted the 3"-UTRs of MICA/B and ULBP2 and negatively regulated the expression of MIA/B and ULBP2.	mica	97-101	UL16 binding protein 2	Homo sapiens	167-172
23820258-15	2013	CONCLUSION: 1,25(OH)2D3 facilitates the immuno-attack of NK cells against malignant cells partly through downregulation of miR-302c and miR-520c and hence upregulation of the NKG2D ligands MICA/B and ULBP2.	mica	189-193	killer cell lectin like receptor K1	Homo sapiens	175-180
23679194-2	2013	Ligands for human NKG2D comprise two groups of MHC class I-related molecules, the MHC class I chain-related proteins A and B (MICA/B) and 6 UL16-binding proteins (ULBP1-6).	mica	126-130	killer cell lectin like receptor K1	Homo sapiens	18-23
23282955-3	2013	Doxycycline inhibits matrix metalloproteinases (MMPs) that act to cleave the extracellular domain of MICA/B, ligands for the NKG2D receptor.	mica	101-105	killer cell lectin like receptor K1	Homo sapiens	125-139
23621148-11	2013	Also, streaming potential measurements of fibrinogen adsorption kinetics on mica were successfully interpreted in terms of this model.	mica	76-80	fibrinogen beta chain	Homo sapiens	42-52
22964480-1	2013	In this study we demonstrate that histone deacetylase (HDAC)-inhibitor mediated cell surface expression of the structural different NKG2D-ligands MICA/B and ULBP2 is calcium-dependent.	mica	146-150	histone deacetylase 9	Homo sapiens	34-53
22984783-23	2013	CONCLUSION: Mica additions to denture PMMA reduced flexural strength; however, with the specimens containing highest mica concentrations (20%), microhardness significantly increased.	mica	117-121	MHC class I polypeptide-related sequence A	Homo sapiens	12-16
23241529-10	2013	Blocking ULBP3 and MICA/B reversed the effects of O3-exposed NECs on IFN-gamma production in NK cells.	mica	19-23	interferon gamma	Homo sapiens	69-78
23465925-3	2013	In this work, we present self-assembled structures starting from spin coated thin films of carboxylated polystyrene (PSC) and xyloglucan (XG) mixtures on both mica and silicon substrates.	mica	159-163	PSC	Homo sapiens	117-120
23645763-4	2013	Major histocompatibility complex class I-related chain A/B (MICA/B) on tumor cells, known as the representative ligand for NKG2D receptor on NK cells, has been reported to be modulated by a variety of stress factors, including some chemotherapeutic agents, and it is anticipated that enhancing MICA/B expression will be contributory to anticancer treatment.	mica	60-64	killer cell lectin like receptor K1	Homo sapiens	123-137
23645763-4	2013	Major histocompatibility complex class I-related chain A/B (MICA/B) on tumor cells, known as the representative ligand for NKG2D receptor on NK cells, has been reported to be modulated by a variety of stress factors, including some chemotherapeutic agents, and it is anticipated that enhancing MICA/B expression will be contributory to anticancer treatment.	mica	294-298	killer cell lectin like receptor K1	Homo sapiens	123-137
23509364-3	2013	In this study, we show that induction of EMT by TGF-beta stimulation of human keratinocytes, by glycogen synthase kinase-3beta inhibition in several epithelial tumor cell lines, and by Snail1 overexpression in colorectal cancer cells strongly upregulated the expression of NKG2D ligands (NKG2DLs), MHC class I chain-related molecules A and B (MICA/B) and ULBP1-3.	mica	343-347	transforming growth factor beta 1	Homo sapiens	48-56
23509364-3	2013	In this study, we show that induction of EMT by TGF-beta stimulation of human keratinocytes, by glycogen synthase kinase-3beta inhibition in several epithelial tumor cell lines, and by Snail1 overexpression in colorectal cancer cells strongly upregulated the expression of NKG2D ligands (NKG2DLs), MHC class I chain-related molecules A and B (MICA/B) and ULBP1-3.	mica	343-347	snail family transcriptional repressor 1	Homo sapiens	185-191
23509364-5	2013	The stimulation of MICA/B expression by TGF-beta treatment was independent of Sp1, but it involved posttranslational mechanisms mediated by mammalian target of rapamycin pathway.	mica	19-23	transforming growth factor beta 1	Homo sapiens	40-48
23509364-8	2013	This decrease of MICA/B expression was associated with a dramatic increase of NKG2D(+)-tumor infiltrating lymphocytes.	mica	17-21	killer cell lectin like receptor K1	Homo sapiens	78-83
23421850-7	2013	The residual protein concentration after making contact with latex particles was determined by electrokinetic measurements and AFM imaging where the surface coverage of fibrinogen on mica was quantitatively determined.	mica	183-187	fibrinogen beta chain	Homo sapiens	169-179
22964480-1	2013	In this study we demonstrate that histone deacetylase (HDAC)-inhibitor mediated cell surface expression of the structural different NKG2D-ligands MICA/B and ULBP2 is calcium-dependent.	mica	146-150	histone deacetylase 9	Homo sapiens	55-59
22964480-1	2013	In this study we demonstrate that histone deacetylase (HDAC)-inhibitor mediated cell surface expression of the structural different NKG2D-ligands MICA/B and ULBP2 is calcium-dependent.	mica	146-150	killer cell lectin like receptor K1	Homo sapiens	132-137
22964480-2	2013	Treatment with the calcium chelator EGTA inhibited constitutive as well as HDAC-inhibitor induced MICA/B and ULBP2 cell surface expression on melanoma cells and Jurkat T-cells.	mica	98-102	histone deacetylase 9	Homo sapiens	75-79
22964480-8	2013	We provide evidence that MICA/B and ULBP2 cell surface expression is controlled differently by calcium, which adds to the increasing perception that cell surface expression of MICA/B and ULBP2 is controlled by distinct signal transduction pathways.	mica	176-180	UL16 binding protein 2	Homo sapiens	36-41
23316196-4	2012	Only in the last few years has it become evident that, upon activation, human T cells express MICA-B, ULBP1-3, and PVR, ligands of the activating receptors NKG2D and DNAM-1, respectively.	mica	94-98	killer cell lectin like receptor K1	Homo sapiens	156-161
23276203-6	2013	We demonstrate that the AFM tip, in either the contact or the tapping mode, can fabricate SF micropatterns on mica with controlled surface topography.	mica	110-114	TOR signaling pathway regulator	Homo sapiens	28-31
23276203-7	2013	We show that the deposition process requires a mechanical force-induced SF sol-gel transition followed by a transfer to the mica surface at the tip-surface contact, and the efficiency of this process depends on not only AFM operation mode but also the SF bulk concentration, the SF amount on mica, and the AFM tip spring constant.	mica	124-128	TOR signaling pathway regulator	Homo sapiens	144-147
23276203-7	2013	We show that the deposition process requires a mechanical force-induced SF sol-gel transition followed by a transfer to the mica surface at the tip-surface contact, and the efficiency of this process depends on not only AFM operation mode but also the SF bulk concentration, the SF amount on mica, and the AFM tip spring constant.	mica	124-128	TOR signaling pathway regulator	Homo sapiens	310-313
23316196-4	2012	Only in the last few years has it become evident that, upon activation, human T cells express MICA-B, ULBP1-3, and PVR, ligands of the activating receptors NKG2D and DNAM-1, respectively.	mica	94-98	CD226 molecule	Homo sapiens	166-172
23010053-0	2013	Mechanism of HSA adsorption on mica determined by streaming potential, AFM and XPS measurements.	mica	31-35	albumin	Homo sapiens	13-16
23010053-1	2013	Adsorption of human serum albumin (HSA) on mica at pH 3.5 (0.15M NaCl) was studied using in situ streaming potential measurements, AFM imaging and XPS.	mica	43-47	albumin	Homo sapiens	20-33
23010053-1	2013	Adsorption of human serum albumin (HSA) on mica at pH 3.5 (0.15M NaCl) was studied using in situ streaming potential measurements, AFM imaging and XPS.	mica	43-47	albumin	Homo sapiens	35-38
23010053-4	2013	It was concluded that HSA adsorption on mica at pH 3.5 occurred under side-on, electrostatically controlled mechanisms with no tendency to multilayer formation.	mica	40-44	albumin	Homo sapiens	22-25
23515568-3	2013	Ves-fusion technique was applied for incorporating AChE G(4) in a lipid layer on mica.	mica	81-85	acetylcholinesterase (Cartwright blood group)	Homo sapiens	51-55
22119572-1	2012	BACKGROUND: The nature of fibrillar deposits from aqueous solutions of human serum and recombinant human transferrin on mica and carbon-coated formvar surfaces has been investigated.	mica	120-124	transferrin	Homo sapiens	105-116
23308050-4	2012	A (51)Cr release assay and degranulation assay indicated that the induction of MICA/B and ULBP2 augmented NK cell-mediated lysis of myeloma cells, which was abolished by the addition of a blocking NKG2D antibody.	mica	79-83	killer cell lectin like receptor K1	Homo sapiens	197-202
23308050-5	2012	Activation of constitutively phosphorylated extracellular signal-regulated kinase (ERK) by VPA is essential for the up-regulation of MICA/B and ULBP2 expressions.	mica	133-137	mitogen-activated protein kinase 1	Homo sapiens	44-81
23308050-5	2012	Activation of constitutively phosphorylated extracellular signal-regulated kinase (ERK) by VPA is essential for the up-regulation of MICA/B and ULBP2 expressions.	mica	133-137	mitogen-activated protein kinase 1	Homo sapiens	83-86
23308050-6	2012	Inhibition of ERK using ERK inhibitor PD98059 decreased both MICA/B and ULBP2 expressions and NK cell cytotoxicity.	mica	61-65	mitogen-activated protein kinase 1	Homo sapiens	14-17
23308050-6	2012	Inhibition of ERK using ERK inhibitor PD98059 decreased both MICA/B and ULBP2 expressions and NK cell cytotoxicity.	mica	61-65	mitogen-activated protein kinase 1	Homo sapiens	24-27
23308050-7	2012	Furthermore, overexpression of constitutively active ERK in ARK resulted in increased MICA/B and ULBP2 expressions and enhanced NK cell lysis.	mica	86-90	mitogen-activated protein kinase 1	Homo sapiens	53-56
23308050-7	2012	Furthermore, overexpression of constitutively active ERK in ARK resulted in increased MICA/B and ULBP2 expressions and enhanced NK cell lysis.	mica	86-90	AXL receptor tyrosine kinase	Homo sapiens	60-63
23057706-0	2012	Human serum albumin monolayers on mica: electrokinetic characteristics.	mica	34-38	albumin	Homo sapiens	12-19
23057706-1	2012	Adsorption of human serum albumin (HSA) on mica from 0.15 M NaCl solutions and various pH values was studied using in situ streaming potential measurements, AFM imaging, and XPS.	mica	43-47	albumin	Homo sapiens	20-39
23057706-6	2012	At pH >10.5, the adsorption of HSA on mica was negligible.	mica	41-45	albumin	Homo sapiens	34-37
22455798-9	2012	MICA was up-regulated after the scald, and this up-regulation was greatly diminished by ulinastatin.	mica	0-4	alpha-1-microglobulin/bikunin precursor	Rattus norvegicus	88-99
22822216-3	2012	We find the S-layer-on-mica system possesses a kinetic trap associated with conformational differences between a long-lived transient state and the final stable state.	mica	23-27	TRAP	Homo sapiens	55-59
22415659-0	2012	Midkine upregulates MICA/B expression in human gastric cancer cells and decreases natural killer cell cytotoxicity.	mica	20-24	midkine	Homo sapiens	0-7
22415659-2	2012	In the current study, a positive correlation was observed between MK expression and MICA/B serum levels of gastric cancer patients.	mica	84-88	midkine	Homo sapiens	66-68
22415659-3	2012	In addition, MK transfection significantly increased MICA/B expression in gastric cancer cells.	mica	53-57	midkine	Homo sapiens	13-15
22415659-7	2012	CHOP was indirectly bound to the MICA/B promoter region by interacting with AP-1, leading to MICA/B transcription.	mica	33-37	DNA damage inducible transcript 3	Homo sapiens	0-4
22415659-7	2012	CHOP was indirectly bound to the MICA/B promoter region by interacting with AP-1, leading to MICA/B transcription.	mica	93-97	DNA damage inducible transcript 3	Homo sapiens	0-4
22065380-3	2012	It was demonstrated that bare mica was superior to APTES-modified mica to keep the tip clean while wearing, which was crucial for DNA pickup during AFM nanomanipulation.	mica	30-34	TOR signaling pathway regulator	Homo sapiens	83-86
22065380-3	2012	It was demonstrated that bare mica was superior to APTES-modified mica to keep the tip clean while wearing, which was crucial for DNA pickup during AFM nanomanipulation.	mica	66-70	TOR signaling pathway regulator	Homo sapiens	83-86
22119572-2	2012	METHODS AND RESULTS: Atomic force microscopy showed that the deposition of recombinant transferrin onto the hydrophilic surface of mica resulted in the formation of a monolayer-thick film composed of conformationally-strained flattened protein molecules.	mica	131-135	transferrin	Homo sapiens	87-98
22316211-3	2012	NKG2D, an activating receptor on NK cells, recognizes MHC class I chain-related molecules, such as MICA/B and members of the ULBP/RAET1 family.	mica	99-103	killer cell lectin like receptor K1	Homo sapiens	0-5
21999960-0	2012	Ionic strength effect in HSA adsorption on mica determined by streaming potential measurements.	mica	43-47	albumin	Homo sapiens	25-28
22065548-4	2012	vWF was printed on plasma-treated glass and mica surfaces, producing elongated network-like fibril structures.	mica	44-48	von Willebrand factor	Homo sapiens	0-3
21999960-1	2012	Adsorption and desorption of human serum albumin (HSA) from aqueous solutions on mica were studied using AFM and in situ streaming potential measurements.	mica	81-85	albumin	Homo sapiens	35-54
21999960-3	2012	These measurements, performed for various ionic strength, allowed one to determine the coverage of HSA as a function of the zeta potential of mica.	mica	142-146	albumin	Homo sapiens	99-102
22189020-3	2012	DNAX accessory molecule-1 (DNAM-1) and NK group 2 member D (NKG2D) are major NK cell activating receptors, which transduce activating signals after binding their ligands CD155, CD112 and major histocompatibility complex class I-related chains A and B (MICA/B).	mica	252-256	CD226 molecule	Homo sapiens	0-25
22242197-8	2012	In contrast, NKG2D ligands ULBP-2 ULBP-3 and MICA/B were not expressed on CD14+ and CD3+ cells, however a variable expression of ULBP-1 was observed.	mica	45-49	killer cell lectin like receptor K1	Homo sapiens	13-18
22189020-3	2012	DNAX accessory molecule-1 (DNAM-1) and NK group 2 member D (NKG2D) are major NK cell activating receptors, which transduce activating signals after binding their ligands CD155, CD112 and major histocompatibility complex class I-related chains A and B (MICA/B).	mica	252-256	CD226 molecule	Homo sapiens	27-33
22189020-3	2012	DNAX accessory molecule-1 (DNAM-1) and NK group 2 member D (NKG2D) are major NK cell activating receptors, which transduce activating signals after binding their ligands CD155, CD112 and major histocompatibility complex class I-related chains A and B (MICA/B).	mica	252-256	killer cell lectin like receptor K1	Homo sapiens	39-58
22189020-3	2012	DNAX accessory molecule-1 (DNAM-1) and NK group 2 member D (NKG2D) are major NK cell activating receptors, which transduce activating signals after binding their ligands CD155, CD112 and major histocompatibility complex class I-related chains A and B (MICA/B).	mica	252-256	killer cell lectin like receptor K1	Homo sapiens	60-65
22189020-3	2012	DNAX accessory molecule-1 (DNAM-1) and NK group 2 member D (NKG2D) are major NK cell activating receptors, which transduce activating signals after binding their ligands CD155, CD112 and major histocompatibility complex class I-related chains A and B (MICA/B).	mica	252-256	PVR cell adhesion molecule	Homo sapiens	170-175
22189020-3	2012	DNAX accessory molecule-1 (DNAM-1) and NK group 2 member D (NKG2D) are major NK cell activating receptors, which transduce activating signals after binding their ligands CD155, CD112 and major histocompatibility complex class I-related chains A and B (MICA/B).	mica	252-256	nectin cell adhesion molecule 2	Homo sapiens	177-182
21815844-1	2011	Human salivary statherin was purified from parotid saliva and adsorbed to bare hydrophilic (HP) mica and STAI-coated hydrophobic (HB) mica in a series of Surface Force Balance experiments that measured the normal (F(n)) and friction forces (F(s)*) between statherin-coated mica substrata.	mica	96-100	statherin	Homo sapiens	15-24
22006996-6	2011	Nitric oxide mimetic agents interfered with the hypoxia-induced accumulation of HIF-1alpha and with the hypoxia-induced upregulation of ADAM10 expression required for decreased surface MICA expression and resistance to lysis.	mica	185-189	a disintegrin and metallopeptidase domain 10	Mus musculus	136-142
21766803-3	2011	In this work, we measure the effects of solution concentration, residence time, and protein competition with BSA on the time-dependent functional changes in adsorbed fibrinogen on mica surface.	mica	180-184	fibrinogen beta chain	Homo sapiens	166-176
21889157-4	2011	The zeta potential of mica modified by the adsorption of cationic polyelectrolytes: PEI and PAH was also determined using the streaming potential measurements.	mica	22-26	phenylalanine hydroxylase	Homo sapiens	92-95
21889157-10	2011	It was also demonstrated that for higher ionic strengths, the maximum coverage of particle monolayers on PAH modified mica exceeded 0.39.	mica	118-122	phenylalanine hydroxylase	Homo sapiens	105-108
21621181-7	2011	Results are discussed, obtained for cationic polyelectrolytes (PEI, PAH) and fibrinogen adsorbing on mica, interpreted quantitatively in terms of the theoretical approach postulating a heterogeneous 3D charge distribution.	mica	101-105	phenylalanine hydroxylase	Homo sapiens	68-71
21621181-7	2011	Results are discussed, obtained for cationic polyelectrolytes (PEI, PAH) and fibrinogen adsorbing on mica, interpreted quantitatively in terms of the theoretical approach postulating a heterogeneous 3D charge distribution.	mica	101-105	fibrinogen beta chain	Homo sapiens	77-87
21815844-1	2011	Human salivary statherin was purified from parotid saliva and adsorbed to bare hydrophilic (HP) mica and STAI-coated hydrophobic (HB) mica in a series of Surface Force Balance experiments that measured the normal (F(n)) and friction forces (F(s)*) between statherin-coated mica substrata.	mica	134-138	statherin	Homo sapiens	15-24
21815844-1	2011	Human salivary statherin was purified from parotid saliva and adsorbed to bare hydrophilic (HP) mica and STAI-coated hydrophobic (HB) mica in a series of Surface Force Balance experiments that measured the normal (F(n)) and friction forces (F(s)*) between statherin-coated mica substrata.	mica	134-138	statherin	Homo sapiens	15-24
21815844-7	2011	The observations were attributed to statherin adsorbing to the mica in multimer aggregates, with internal re-arrangement of the protein molecules within the aggregate dependent on the substratum to which the aggregate adsorbed.	mica	63-67	statherin	Homo sapiens	36-45
21644031-7	2011	DNAM-1 ligands are frequently expressed on blasts, whereas the expression of the NKG2D ligand MICA/B is found in half of the patients and CD48, a ligand for CD244, in only one-fourth of the patients.	mica	94-98	killer cell lectin like receptor K1	Homo sapiens	81-86
21860374-6	2011	By coating freshly cleaved mica surfaces with porcine (pig) gelatin, negatively charged bacteria can be immobilized on the surface and imaged in liquid by AFM.	mica	27-31	afamin	Sus scrofa	155-158
21452804-5	2011	We have studied the influence of hydrophobicity on the surface-catalyzed assembly of IAPP on ultrasmooth hydrocarbon films grown on ion-beam-modified mica surfaces by atomic force microscopy.	mica	150-154	islet amyloid polypeptide	Homo sapiens	85-89
21542606-12	2011	In this way, magnetic AFM tips could be functionalized with an ethylene diamine derivative of ATP which showed specific interaction with mitochondrial uncoupling protein 1 (UCP1) that had been purified and reconstituted in a mica-supported planar lipid bilayer.	mica	225-229	solute carrier family 25 member 19	Homo sapiens	137-171
21542606-12	2011	In this way, magnetic AFM tips could be functionalized with an ethylene diamine derivative of ATP which showed specific interaction with mitochondrial uncoupling protein 1 (UCP1) that had been purified and reconstituted in a mica-supported planar lipid bilayer.	mica	225-229	uncoupling protein 1	Homo sapiens	173-177
22778873-7	2011	However, aggregation occurring directly on a negatively charged mica surface resulted in distinct aggregate morphologies formed by different mutant forms of Abeta.	mica	64-68	amyloid beta precursor protein	Homo sapiens	157-162
21377446-8	2011	When P59 and gp41-FP were incubated together, annular structures of about 200 nm in diameter appeared on the mica surface, thus indicating a peptide-peptide interaction.	mica	109-113	HLA complex P5B	Homo sapiens	5-8
21918653-4	2011	Here, we use atomic force microscopy (AFM) and molecular dynamics (MD) simulations to demonstrate that at room temperature a truncated Abeta peptide which is generated in vivo and shown to be toxic in vitro forms fibrillar structures on hydrophobic graphite surfaces, but not on hydrophilic mica or lipid bilayers.	mica	291-295	amyloid beta precursor protein	Homo sapiens	135-140
21341680-9	2011	The lower friction with HB relative to HP mica suggests a selectivity of the HB surface to the hydrophobic moieties of the mucin that in consequence exposes relatively more of the better-lubricating hydrophilic groups.	mica	42-46	LOC100508689	Homo sapiens	123-128
21364924-3	2011	Using real-time quantitative RT-PCR and immunoflow cytometry we show that Jurkat and Raji cells constitutively express mRNA and protein for the stress-inducible NKG2D ligands MICA/B and ULBP1 and 2, and up-regulate the expression in a cell-line specific and stress-specific manner.	mica	175-179	killer cell lectin like receptor K1	Homo sapiens	161-166
21185149-5	2011	To address this issue, we have taken advantage of our expertise with atomic force microscopy and studied anti-annexin A5 autoantibodies isolated from patients and focused on the ability of these antibodies to influence annexin A5 crystallization on planar mica-supported phospholipid bilayers.	mica	256-260	annexin A5	Homo sapiens	219-229
21364924-3	2011	Using real-time quantitative RT-PCR and immunoflow cytometry we show that Jurkat and Raji cells constitutively express mRNA and protein for the stress-inducible NKG2D ligands MICA/B and ULBP1 and 2, and up-regulate the expression in a cell-line specific and stress-specific manner.	mica	175-179	UL16 binding protein 1	Homo sapiens	186-197
20226591-3	2010	The lateral oscillation amplitude of the tuning fork was used as feedback signal for topographical imaging of avidin aggregates and lysozyme molecules on mica substrate.	mica	154-158	lysozyme	Homo sapiens	132-140
21192636-3	2011	The conformational analysis of a large population of fibrinogen molecules on mica revealed the two most energetically favorable conformations characterized by bending angles of ~100 and 160 degrees.	mica	77-81	fibrinogen beta chain	Homo sapiens	53-63
21192636-5	2011	Imaging in different environments supports the expected hydration of the fibrinogen molecules in buffer, whereas imaging in humid air suggests the 2D spreading of fibrinogen on mica induced by an adsorbed water layer.	mica	177-181	fibrinogen beta chain	Homo sapiens	163-173
21821960-2	2011	The formation of lactose caprate from lactose sugar and capric acid, using free lipase (free-CRL) and lipase immobilized on nanoporous mica (NER-CRL) as a biocatalyst, was evaluated through a kinetic study.	mica	135-139	interleukin 31 receptor A	Homo sapiens	145-148
21168719-10	2010	NKG2D+ cell counts that increased in the graft colocalized with MICA/B.	mica	64-68	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	0-5
20603671-1	2010	Aleuritic (9,10,16-trihydroxypalmitic) acid self-assembly on mica from solution has been studied using AFM, ATR-FTIR and MD simulations.	mica	61-65	ATR serine/threonine kinase	Homo sapiens	108-111
20452198-4	2010	NF-kappaB target sequence DNA has been employed to mica functionalization in order to set up a surface able to capture transcriptionally active NF-kappaB protein complexes from cell lysates, with the aim to detect DNA binding capacity of NF-kappaB from low amount of biological samples such as biopsy.	mica	51-55	nuclear factor kappa B subunit 1	Homo sapiens	0-9
20452198-4	2010	NF-kappaB target sequence DNA has been employed to mica functionalization in order to set up a surface able to capture transcriptionally active NF-kappaB protein complexes from cell lysates, with the aim to detect DNA binding capacity of NF-kappaB from low amount of biological samples such as biopsy.	mica	51-55	nuclear factor kappa B subunit 1	Homo sapiens	144-153
20452198-4	2010	NF-kappaB target sequence DNA has been employed to mica functionalization in order to set up a surface able to capture transcriptionally active NF-kappaB protein complexes from cell lysates, with the aim to detect DNA binding capacity of NF-kappaB from low amount of biological samples such as biopsy.	mica	51-55	nuclear factor kappa B subunit 1	Homo sapiens	144-153
20226163-4	2010	Surprisingly high-speed Abeta aggregation of fibril formations occurred at all GM1 concentrations examined on the mica surface, but on the SiO(2) surface, only globular agglomerates formed and they formed slowly.	mica	114-118	amyloid beta precursor protein	Homo sapiens	24-29
20927466-7	2010	This study illustrates that changes in the tertiary structure of DNA can be induced during AFM imaging at high humidity on mica.	mica	123-127	afamin	Homo sapiens	91-94
20586320-3	2010	During this test, we have obtained distinct precise AFM images of lysozyme monomers adsorbed from a clear aqueous solution onto a mica wafer.	mica	130-134	lysozyme	Homo sapiens	66-74
19699729-5	2009	These results suggest that cyt c molecules might intercalate between the mica and the lipid bilayer.	mica	73-77	cytochrome c, somatic	Homo sapiens	27-32
20356127-1	2009	Nanometer-scale silicate platelet (NSP) materials were previously developed by increasing the interlayer space and exfoliation of layered silicate clays such as montmorillonite and synthetic fluorinated mica by the process of polyamine exfoliation.	mica	203-207	reticulon 1	Homo sapiens	35-38
19888472-7	2009	We found a good agreement between the contours of the deposited vimentin filaments on mica ("ideal" trapping) and on glass ("ideal" equilibrated) with our simulations.	mica	86-90	vimentin	Homo sapiens	64-72
19699729-6	2009	Although the interaction of cyt c with the mica surface is likely to be an artifact, this work is the first direct observation of cyt c ability to cross membranes.	mica	43-47	cytochrome c, somatic	Homo sapiens	28-33
19619933-3	2009	GpA was mounted on a mica surface or natively presented on the erythrocyte membrane and probed with an AFM tip coated with the monomeric but multivalent Psathyrella velutina lectin (PVL) through covalent crosslinkers.	mica	21-25	glycophorin A (MNS blood group)	Homo sapiens	0-3
19203838-7	2009	MICA was up-regulated after the scald, and this up-regulation was greatly diminished by ulinastatin.	mica	0-4	alpha-1-microglobulin/bikunin precursor	Rattus norvegicus	88-99
18791713-1	2009	OBJECTIVE: To investigate the clinical significance of the expression of the NKG2D ligands MICA/B and ULBP2 in ovarian cancer.	mica	91-95	killer cell lectin like receptor K1	Homo sapiens	77-82
20596481-4	2009	We demonstrate that by using Dip-Pen Nanolithography, individual DNA molecules attached to modified mica surfaces can be efficiently digested by DNase I.	mica	100-104	proprotein convertase subtilisin/kexin type 1 inhibitor	Homo sapiens	33-36
19447870-10	2009	CONCLUSIONS: Murine NKG2D recognition of MICA/B is an important receptor-ligand interaction used by NK cells in immunodeficient strains to limit engraftment of human tumors.	mica	41-45	killer cell lectin-like receptor subfamily K, member 1	Mus musculus	20-25
19374400-1	2009	We report the direct observation of solidlike ordering at room temperature of thin films of [Bmim][NTf2] ionic liquid on mica, amorphous silica, and oxidized Si(110).	mica	121-125	nuclear transport factor 2	Homo sapiens	99-103
18791713-6	2009	The expression of MICA/B in ovarian cancer was highly correlated with that of ULBP2.	mica	18-22	UL16 binding protein 2	Homo sapiens	78-83
19360949-1	2008	The fibronectin (Fn) binding conformation on mica and ultraflat poly(D,L-lactide-co-glycolide) (UPLGA) was characterized using atomic force microscopy (AFM).	mica	45-49	fibronectin 1	Homo sapiens	4-15
19186036-0	2009	Dissimilar pH-dependent adsorption features of bovine serum albumin and alpha-chymotrypsin on mica probed by AFM.	mica	94-98	albumin	Homo sapiens	54-67
19360949-1	2008	The fibronectin (Fn) binding conformation on mica and ultraflat poly(D,L-lactide-co-glycolide) (UPLGA) was characterized using atomic force microscopy (AFM).	mica	45-49	fibronectin 1	Homo sapiens	17-19
19360949-2	2008	AFM topographic images showed that Fn was in an extended form on mica and in a compact structure on UPLGA.	mica	65-69	fibronectin 1	Homo sapiens	35-37
19360949-7	2008	Mean true height values were obtained from the histograms and showed that Fn and Ab(hep) formed complexes on mica, signifying that one of the heparin binding sites on Fn was open when Fn was adsorbed to mica.	mica	109-113	fibronectin 1	Homo sapiens	74-76
19360949-7	2008	Mean true height values were obtained from the histograms and showed that Fn and Ab(hep) formed complexes on mica, signifying that one of the heparin binding sites on Fn was open when Fn was adsorbed to mica.	mica	109-113	fibronectin 1	Homo sapiens	167-169
19360949-7	2008	Mean true height values were obtained from the histograms and showed that Fn and Ab(hep) formed complexes on mica, signifying that one of the heparin binding sites on Fn was open when Fn was adsorbed to mica.	mica	109-113	fibronectin 1	Homo sapiens	167-169
19360949-7	2008	Mean true height values were obtained from the histograms and showed that Fn and Ab(hep) formed complexes on mica, signifying that one of the heparin binding sites on Fn was open when Fn was adsorbed to mica.	mica	203-207	fibronectin 1	Homo sapiens	74-76
19360949-7	2008	Mean true height values were obtained from the histograms and showed that Fn and Ab(hep) formed complexes on mica, signifying that one of the heparin binding sites on Fn was open when Fn was adsorbed to mica.	mica	203-207	fibronectin 1	Homo sapiens	167-169
19360949-7	2008	Mean true height values were obtained from the histograms and showed that Fn and Ab(hep) formed complexes on mica, signifying that one of the heparin binding sites on Fn was open when Fn was adsorbed to mica.	mica	203-207	fibronectin 1	Homo sapiens	167-169
19000131-8	2008	MICA*00801 truncated product, and its low affinity for NKG2D receptor may work as an inhibitor in its putative soluble form.	mica	0-4	killer cell lectin like receptor K1	Homo sapiens	55-69
19000131-9	2008	It may also be that selective forces may favor MICA*00801 heterozygosity with NKG2D high affinity MICA alleles enabling activation and inhibition of cytotoxic activity of cells expressing the NKG2D receptor.	mica	47-51	killer cell lectin like receptor K1	Homo sapiens	192-206
19000131-9	2008	It may also be that selective forces may favor MICA*00801 heterozygosity with NKG2D high affinity MICA alleles enabling activation and inhibition of cytotoxic activity of cells expressing the NKG2D receptor.	mica	98-102	killer cell lectin like receptor K1	Homo sapiens	192-206
18973362-4	2008	One system consists of a square-well fluid interacting with a square-well substrate, and the other contains an embedded point charge model of lysozyme interacting with a mica surface.	mica	170-174	lysozyme	Homo sapiens	142-150
18937403-1	2008	We prepared amyloid-like fibrinogen (Fg) fibrils at pH 2.0 in the absence of thrombin; furthermore, we prepared uniform 2-D Fg fibril networks on a hydrophilic mica matrix.	mica	160-164	fibrinogen beta chain	Homo sapiens	124-126
20408656-0	2008	Measurement of interaction forces between fibrinogen coated probes and mica surface with the atomic force microscope: The pH and ionic strength effect.	mica	71-75	fibrinogen beta chain	Homo sapiens	42-52
19058239-3	2008	For each disease, a linear regression model predicted PHR from behavior, access, and disease prevalence data from MICA and other public data sources.	mica	114-118	MYC binding protein 2	Homo sapiens	54-57
18758006-1	2008	In contrast with the multiple twinning and/or domain formation found in the mica-like polymorphs of CaTe(2)O(5), calcium pentaoxidoditellurate(IV), that have been prepared by solid-state reactions and for which complete structure determinations have not been successful up to now, the crystal structure of a hydrothermally grown phase was fully determined from a non-twinned crystal.	mica	76-80	cathepsin E	Homo sapiens	100-104
18189132-3	2008	Recently, we have shown that amyloid beta 25-35 (A beta 25-35) forms a highly oriented, K(+)-dependent network on mica.	mica	114-118	amyloid beta precursor protein	Homo sapiens	49-55
18189132-5	2008	We find that A beta 25-35_N27C forms epitaxially growing fibrils on mica, which evolve into a trigonally oriented branched network.	mica	68-72	amyloid beta precursor protein	Homo sapiens	13-19
18616311-3	2008	These probes were used to collect force measurements between the antibody and fibrinogen on mica substrates and the probability of antigen recognition was calculated.	mica	92-96	fibrinogen beta chain	Homo sapiens	78-88
18616311-5	2008	Macroscale platelet adhesion measurements on these mica substrates were determined to be greatest at fibrinogen residence times of approximately 45 min, which correlated well with the functional activity of adsorbed fibrinogen as measured by the modified AFM probes.	mica	51-55	fibrinogen beta chain	Homo sapiens	101-111
18616311-5	2008	Macroscale platelet adhesion measurements on these mica substrates were determined to be greatest at fibrinogen residence times of approximately 45 min, which correlated well with the functional activity of adsorbed fibrinogen as measured by the modified AFM probes.	mica	51-55	fibrinogen beta chain	Homo sapiens	216-226
17764010-12	2008	However, NKG2D receptor could deliver a costimulatory signal enhancing the lysis of HCC and CRC tumors expressing MICA/B.	mica	114-118	killer cell lectin like receptor K1	Homo sapiens	9-23
18201941-2	2008	A monoclonal single-chain variable fragment (scFv) targeting insulin fibrils was isolated using phage display technology and an atomic force microscopy (AFM) mica substrate.	mica	158-162	immunglobulin heavy chain variable region	Homo sapiens	45-49
18201941-2	2008	A monoclonal single-chain variable fragment (scFv) targeting insulin fibrils was isolated using phage display technology and an atomic force microscopy (AFM) mica substrate.	mica	158-162	insulin	Homo sapiens	61-68
18652418-1	2008	To provide better understanding of how a protein secondary structure affects protein-protein and protein-surface interactions, forces between amphiphilic alpha-helical proteins (human apolipoprotein AII) adsorbed on a hydrophilic surface (mica) were measured using an interferometric surface force apparatus (SFA).	mica	239-243	apolipoprotein A2	Homo sapiens	184-202
18495144-2	2008	We have shown that the normal interactions between mucin coated mica and silica surfaces are dominated by long-range steric repulsion on both compression and decompression.	mica	64-68	LOC100508689	Homo sapiens	51-56
17872962-7	2008	Dynamic force measurements showed similar results for TfR on mica or at the cell surface but revealed striking differences between holo-Tf-TfR and apo-Tf-TfR interactions.	mica	61-65	transferrin receptor	Homo sapiens	54-57
20408656-2	2008	The authors have used atomic force microscopy (AFM) to directly measure the force of attraction/adhesion of fibrinogen coated tips to mica surfaces and reveal the effect of the surrounding solution pH and ionic strength on this interaction.	mica	134-138	fibrinogen beta chain	Homo sapiens	108-118
17887784-4	2007	According to the step-height differences, cyt c was able to remove neutral lipids in the fluid phase and then to reside on the mica surface.	mica	127-131	cytochrome c, somatic	Homo sapiens	42-47
18350884-7	2008	The EPR spectra of Cu-exchanged micas coincide with the mica"s charge characteristics that predict increased binding strength of exchangeable Cu in Na-4-mica and Na-3-mica than in Na-2-mica.	mica	32-37	MHC class I polypeptide-related sequence A	Homo sapiens	56-60
18350884-7	2008	The EPR spectra of Cu-exchanged micas coincide with the mica"s charge characteristics that predict increased binding strength of exchangeable Cu in Na-4-mica and Na-3-mica than in Na-2-mica.	mica	32-37	MHC class I polypeptide-related sequence A	Homo sapiens	56-60
18350884-7	2008	The EPR spectra of Cu-exchanged micas coincide with the mica"s charge characteristics that predict increased binding strength of exchangeable Cu in Na-4-mica and Na-3-mica than in Na-2-mica.	mica	32-37	MHC class I polypeptide-related sequence A	Homo sapiens	56-60
19195555-6	2008	On mica, a two-stage sequential conversion of amylin from soluble monomer to small oligomers and further to mature amyloid fibrils was revealed by the AFM.	mica	3-7	islet amyloid polypeptide	Homo sapiens	46-52
17887784-5	2007	Concerning gel phases, cyt c might insert between the two lipid leaflets, or it might intercalate between the mica and the bilayer.	mica	110-114	cytochrome c, somatic	Homo sapiens	23-28
17045469-1	2007	This work reports the first evidence that recombinant yeast phosphoglycerate kinase (PGK) is still significantly active when immobilized on glass and muscovite mica.	mica	160-164	phosphoglycerate kinase	Saccharomyces cerevisiae S288C	60-83
17512706-5	2007	Careful measurements indicate the Tet1.5 G-wires orient along the b lattice vector of mica, the next nearest neighbor potassium vacancy.	mica	86-90	tet methylcytosine dioxygenase 1	Homo sapiens	34-38
17594804-10	2007	CONCLUSION: A cell model with the expression of HBV antigens and the secretion of HBV DNA was established by pEcob6 transfection into L02 cells, the transcription or replication of HBV gene might induce stronger expressions of HLA-A, B, C and MICA/B on hepatic cells.	mica	243-247	major histocompatibility complex, class I, A	Homo sapiens	227-235
17911639-6	2007	Interestingly, a counter selection was observed against the expression of MICA/B in HSP70-overexpressing tumors compared with control tumors in SCID, but not in SCID/beige mice, suggesting a functional relevance of MICA/B expression.	mica	74-78	heat shock protein 1B	Mus musculus	84-89
17911639-6	2007	Interestingly, a counter selection was observed against the expression of MICA/B in HSP70-overexpressing tumors compared with control tumors in SCID, but not in SCID/beige mice, suggesting a functional relevance of MICA/B expression.	mica	215-219	heat shock protein 1B	Mus musculus	84-89
17911639-8	2007	HSP70-positive exosomes from the HSP70-overexpressing cells, in contrast to HSP70-negative exosomes from the control cells, were able to activate mouse NK cells in vitro to kill YAC-1 cells, which express NKG2D ligands constitutively, or the human melanoma cells, in which MICA/B expression was induced.	mica	273-277	heat shock protein 1B	Mus musculus	0-5
17911639-8	2007	HSP70-positive exosomes from the HSP70-overexpressing cells, in contrast to HSP70-negative exosomes from the control cells, were able to activate mouse NK cells in vitro to kill YAC-1 cells, which express NKG2D ligands constitutively, or the human melanoma cells, in which MICA/B expression was induced.	mica	273-277	heat shock protein 1B	Mus musculus	33-38
17911639-8	2007	HSP70-positive exosomes from the HSP70-overexpressing cells, in contrast to HSP70-negative exosomes from the control cells, were able to activate mouse NK cells in vitro to kill YAC-1 cells, which express NKG2D ligands constitutively, or the human melanoma cells, in which MICA/B expression was induced.	mica	273-277	heat shock protein 1B	Mus musculus	33-38
17931181-7	2007	In response to IFN-alpha, DC are able to express MHC class-I related chain A/B (MICA/B) and activate natural killer (NK) cells following ligation of NKG2D.	mica	80-84	interferon alpha 1	Homo sapiens	15-24
17931181-8	2007	Interestingly, DC from HCV-infected patients are unresponsive to exogenous IFN-alpha to enhance MICA/B expression and fail to activate NK cells.	mica	96-100	interferon alpha 1	Homo sapiens	75-84
17045469-1	2007	This work reports the first evidence that recombinant yeast phosphoglycerate kinase (PGK) is still significantly active when immobilized on glass and muscovite mica.	mica	160-164	phosphoglycerate kinase	Saccharomyces cerevisiae S288C	85-88
17142292-5	2007	For pressures up to approximately 6 atm, lubricin lubricates hydrophilic surfaces, in particular negatively charged mica (friction coefficient mu = 0.02-0.04), much better than hydrophobic surfaces (mu > 0.3).	mica	116-120	proteoglycan 4	Homo sapiens	41-49
17261045-7	2007	These results agreed with those obtained for LOx submonolayer deposits on mica substrates, which allows discarding any important contribution from the underlying substrate on the measured properties.	mica	74-78	lysyl oxidase	Homo sapiens	45-48
17332360-3	2007	Fluorescence-activated cell sorting analysis revealed that LNCaP tumor cells bear negligible levels of MHC class I molecules; yet, they express MICA/B molecules, ligands for the NKG2D receptors found on NK cells.	mica	144-148	killer cell lectin like receptor K1	Homo sapiens	178-183
17170457-3	2007	This study was designed to evaluate whether HIV-1 could interfere with the expression of NK cell-activating ligands, specifically the human leukocyte antigen (HLA)-I-like MICA and ULBP molecules that bind NKG2D, an activating receptor expressed by all NK cells.	mica	171-175	killer cell lectin like receptor K1	Homo sapiens	205-210
17170457-4	2007	Results show that the HIV-1 Nef protein downmodulates cell-surface expression of MICA, ULBP1 and ULBP2, with a stronger effect on the latter molecule.	mica	81-85	Nef	Human immunodeficiency virus 1	28-31
17170457-5	2007	The activity on MICA and ULBP2 is well conserved in Nef protein variants derived from HIV-1-infected patients.	mica	16-20	Nef	Human immunodeficiency virus 1	52-55
16927188-2	2006	METHODS: AFM images of phosphatidylcholine/cholesterol vesicles were obtained using a mucin-coated mica substrate.	mica	99-103	LOC100508689	Homo sapiens	86-91
17337166-0	2007	pH and ionic strength effect on single fibrinogen molecule adsorption on mica studied with AFM.	mica	73-77	fibrinogen beta chain	Homo sapiens	39-49
17337166-2	2007	We have used atomic force microscopy to image, in phosphate buffer, single fibrinogen molecules adsorbed on mica and compare the surface coverage at variable pH (7.4, 5.8, 3.5) or ionic strength (15, 150, 500 mM) conditions.	mica	108-112	fibrinogen beta chain	Homo sapiens	75-85
17267578-6	2007	NKG2D ligands [major histocompatibility complex class I chain-related molecules A and B (MICA/B)] were detected in groups of cells and colocalized with an oligodendrocyte marker (adenomatous polyposis coli) in white matter sections obtained from multiple sclerosis lesions but not in normal control samples.	mica	89-93	killer cell lectin like receptor K1	Homo sapiens	0-5
17214498-9	2007	Furthermore, it was found that the flat-lying DNA monolayers could still form on a mica surface when plasmid DNA pBR 322 and linear DNA pBR 322/Pst I were used as the DNA source.	mica	83-87	translocator protein	Homo sapiens	113-116
17214498-9	2007	Furthermore, it was found that the flat-lying DNA monolayers could still form on a mica surface when plasmid DNA pBR 322 and linear DNA pBR 322/Pst I were used as the DNA source.	mica	83-87	translocator protein	Homo sapiens	136-139
17392343-4	2007	The point is that adsorption of ssDN A-SSB complexes on mica, necessary for AFM imaging, is not an easy task.	mica	56-60	single-stranded DNA-binding protein	Escherichia coli	39-42
17392343-7	2007	At low spermidine concentration (<0.3 mM), we obtained AFM images of ssDNA-SSB complexes (E. coli SSB, gp32 and yRPA) on mica at both low and high ionic strengths.	mica	124-128	single-stranded DNA-binding protein	Escherichia coli	78-81
17392343-7	2007	At low spermidine concentration (<0.3 mM), we obtained AFM images of ssDNA-SSB complexes (E. coli SSB, gp32 and yRPA) on mica at both low and high ionic strengths.	mica	124-128	single-stranded DNA-binding protein	Escherichia coli	101-104