PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
22999639-0	2013	Expression of Egr1 and p53 in human carotid plaques and apoptosis induced by 7-oxysterol or p53.	7-oxysterol	77-88	early growth response 1	Homo sapiens	14-18
22999639-5	2013	Cells with nuclear fragmentation induced by 7-oxysterol or p53 showed increased levels of p53, but decreased levels of Egr1.	7-oxysterol	44-55	tumor protein p53	Homo sapiens	90-93
22999639-5	2013	Cells with nuclear fragmentation induced by 7-oxysterol or p53 showed increased levels of p53, but decreased levels of Egr1.	7-oxysterol	44-55	early growth response 1	Homo sapiens	119-123
27079462-7	2016	Third, macrophages isolated from CysC(-/-) mice displayed increased levels of p62/SQSTM1 and higher sensitivity to 7-oxysterol-mediated lysosomal membrane destabilization and apoptosis.	7-oxysterol	115-126	cystatin C	Mus musculus	33-37
22940536-0	2013	11beta-Hydroxysteroid dehydrogenase type 1 contributes to the regulation of 7-oxysterol levels in the arterial wall through the inter-conversion of 7-ketocholesterol and 7beta-hydroxycholesterol.	7-oxysterol	76-87	hydroxysteroid 11-beta dehydrogenase 1	Mus musculus	0-42
22940536-10	2013	These results demonstrate that 7-KC has greater effects than 7betaOHC on vascular function, and that 11beta-HSD1 can inter-convert 7-KC and 7betaOHC in the arterial wall, contributing to the regulation of 7-oxysterol levels and potentially influencing vascular function.	7-oxysterol	205-216	hydroxysteroid 11-beta dehydrogenase 1	Mus musculus	101-112
22985798-5	2012	The role of p53 in 7-oxysterol-mediated cell death is further investigated in temperature sensitive p53-transfected (M1-t-p53) and in p53-deficient (M1) cells.	7-oxysterol	19-30	tumor protein p53	Homo sapiens	12-15
22985798-8	2012	The findings reveal that 7-oxysterol-induced cell death occurs via p53-dependent pathways.	7-oxysterol	25-36	tumor protein p53	Homo sapiens	67-70
22535762-10	2012	Taken together, our results show that the anthocyanin C3G prevents or reverses hypercholesterolemia-induced endothelial dysfunction by inhibiting cholesterol and 7-oxysterol accumulation in the aorta and the subsequent decrease in superoxide production, thereby preserving eNOS activity and NO bioavailability.	7-oxysterol	162-173	Rap guanine nucleotide exchange factor (GEF) 1	Mus musculus	54-57
20798376-2	2010	METHODS AND RESULTS: ABCG1 promotes cholesterol and 7-oxysterol efflux from endothelial cells (ECs) to HDL.	7-oxysterol	52-63	ATP binding cassette subfamily G member 1	Mus musculus	21-26