PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
20079805-11	2010	The activity of the inducible isoform (iNOS) was inhibited by the three types of treatment (-31.8% for ASA, -29.1% for VOO and -56.0% for ASA plus VOO).	voo	119-122	nitric oxide synthase 2	Rattus norvegicus	39-43
20079805-11	2010	The activity of the inducible isoform (iNOS) was inhibited by the three types of treatment (-31.8% for ASA, -29.1% for VOO and -56.0% for ASA plus VOO).	voo	147-150	nitric oxide synthase 2	Rattus norvegicus	39-43
22535754-8	2012	When participants were categorized in tertiles of 1-y changes in the consumption of selected foods, those in the highest tertile of virgin olive oil (VOO) and vegetable consumption had a lower plasma TNFR60 concentration compared with those in tertile 1 (P < 0.02).	voo	150-153	TNF receptor superfamily member 1A	Homo sapiens	200-206
16131150-6	2005	Conversely, VOO reduced the LPL and non-LPL lipolytic activities, hence limiting the free fatty acids available for the synthesis of TG and CE in the vascular wall.	voo	12-15	lipoprotein lipase	Rattus norvegicus	28-31
16131150-6	2005	Conversely, VOO reduced the LPL and non-LPL lipolytic activities, hence limiting the free fatty acids available for the synthesis of TG and CE in the vascular wall.	voo	12-15	lipoprotein lipase	Rattus norvegicus	40-43
27155966-5	2016	Using western blot to determine the effect of these samples on Abeta-induced activation of pERK1/2, p38, and JNK MAPKs, results revealed that both VOO and Hc acids inhibited the activation of pERK1/2 and p-p38 MAPK, but not JNK.	voo	147-150	mitogen-activated protein kinase 14	Homo sapiens	100-103
27155966-5	2016	Using western blot to determine the effect of these samples on Abeta-induced activation of pERK1/2, p38, and JNK MAPKs, results revealed that both VOO and Hc acids inhibited the activation of pERK1/2 and p-p38 MAPK, but not JNK.	voo	147-150	mitogen-activated protein kinase 8	Homo sapiens	109-112
27155966-5	2016	Using western blot to determine the effect of these samples on Abeta-induced activation of pERK1/2, p38, and JNK MAPKs, results revealed that both VOO and Hc acids inhibited the activation of pERK1/2 and p-p38 MAPK, but not JNK.	voo	147-150	mitogen-activated protein kinase 14	Homo sapiens	206-209
27155966-5	2016	Using western blot to determine the effect of these samples on Abeta-induced activation of pERK1/2, p38, and JNK MAPKs, results revealed that both VOO and Hc acids inhibited the activation of pERK1/2 and p-p38 MAPK, but not JNK.	voo	147-150	mitogen-activated protein kinase 8	Homo sapiens	224-227
27155966-6	2016	Moreover, VOO upregulated the glycolytic enzymes genes hexokinase (HK1), and phosphofructokinase (PFKM) expression which means that VOO enhanced the energy metabolism of the neurotypic cells, and therefore suggests another mechanism by which VOO could provide protection against Abeta-induced cytotoxicity.	voo	10-13	hexokinase 1	Homo sapiens	67-70
27155966-6	2016	Moreover, VOO upregulated the glycolytic enzymes genes hexokinase (HK1), and phosphofructokinase (PFKM) expression which means that VOO enhanced the energy metabolism of the neurotypic cells, and therefore suggests another mechanism by which VOO could provide protection against Abeta-induced cytotoxicity.	voo	132-135	hexokinase 1	Homo sapiens	67-70
27155966-7	2016	The findings in this study suggest that VOO has a neuroprotective effect, attributable to its hydroxycinnamic acids component, against Abeta-induced cytotoxicity and oxidative stress through the inhibition of the activation of MAPKs ERK and p38 and by enhancing the energy metabolism of the neurotypic cells.	voo	40-43	mitogen-activated protein kinase 14	Homo sapiens	241-244