PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
22326953-7	2012	GSK-3alpha-specific suppression also led to impaired growth and proliferation in vitro, induction of apoptosis, loss of colony formation in methylcellulose, and anti-AML activity in vivo.	Methylcellulose	140-155	glycogen synthase kinase 3 alpha	Homo sapiens	0-10
21262971-12	2011	Furthermore, FL-stimulated colony formation of 32D cells expressing FLT3 in methylcellulose was induced in response to shRNA-mediated DEP-1 knockdown.	Methylcellulose	76-91	FMS-like tyrosine kinase 3 ligand	Mus musculus	13-15
21907798-9	2011	Periocular injection of Cx43 antisense oligonucleotides (AsODN) incorporated in the MC-IC system lead to a significant reduction in the Cx43 levels in the choroid of rats at 24 h of treatment.	Methylcellulose	84-86	gap junction protein, alpha 1	Rattus norvegicus	24-28
21907798-9	2011	Periocular injection of Cx43 antisense oligonucleotides (AsODN) incorporated in the MC-IC system lead to a significant reduction in the Cx43 levels in the choroid of rats at 24 h of treatment.	Methylcellulose	84-86	gap junction protein, alpha 1	Rattus norvegicus	136-140
21262971-12	2011	Furthermore, FL-stimulated colony formation of 32D cells expressing FLT3 in methylcellulose was induced in response to shRNA-mediated DEP-1 knockdown.	Methylcellulose	76-91	FMS-like tyrosine kinase 3	Mus musculus	68-72
21262971-12	2011	Furthermore, FL-stimulated colony formation of 32D cells expressing FLT3 in methylcellulose was induced in response to shRNA-mediated DEP-1 knockdown.	Methylcellulose	76-91	diabetic embryopathy 1	Mus musculus	134-139
20666608-3	2010	Overall, MC-x-LN1 enhanced both NSC survival and maturation compared with MC controls.	Methylcellulose	9-11	NZ lupus nephritis 1	Mus musculus	14-17
20666608-4	2010	Significantly lower levels of apoptotic activity were observed in MC-x-LN1 than in MC controls, as measured by bcl-2/bax gene expression and tetramethylrhodamine-dUTP nick end labeling.	Methylcellulose	66-68	NZ lupus nephritis 1	Mus musculus	71-74
20666608-5	2010	A higher percentage of NSCs extended neurites in a beta1-integrin-mediated fashion in MC-x-LN1 than in MC controls.	Methylcellulose	86-88	NZ lupus nephritis 1	Mus musculus	91-94
20666608-6	2010	Further, the differentiation profiles of NSCs in MC-x-LN1 exhibited higher levels of neuronal and oligodendrocyte precursor markers than in MC controls.	Methylcellulose	49-51	NZ lupus nephritis 1	Mus musculus	54-57
20666608-7	2010	LN1 production and co-localization with alpha6beta1 integrins was markedly increased within MC-x-LN1, whereas the production of fibronectin was more pronounced in MC controls.	Methylcellulose	92-94	NZ lupus nephritis 1	Mus musculus	0-3
20646200-3	2010	To study the prophylactic and therapeutic effects of GaM against Rhodococcus equi pneumonia in foals, we developed a methylcellulose formulation of GaM (GaM-MCF) for oral administration to neonatal foals.	Methylcellulose	117-132	glutaminase	Homo sapiens	148-151
20646200-3	2010	To study the prophylactic and therapeutic effects of GaM against Rhodococcus equi pneumonia in foals, we developed a methylcellulose formulation of GaM (GaM-MCF) for oral administration to neonatal foals.	Methylcellulose	117-132	glutaminase	Homo sapiens	148-151
20237089-2	2010	Nucleophosmin (NPM) was identified as a protein with increased levels in two-dimensional (2-D) gel analysis of human foreskin keratinocytes (HFKs) expressing E7 following methylcellulose-induced differentiation.	Methylcellulose	171-186	nucleophosmin 1	Homo sapiens	0-13
20237089-2	2010	Nucleophosmin (NPM) was identified as a protein with increased levels in two-dimensional (2-D) gel analysis of human foreskin keratinocytes (HFKs) expressing E7 following methylcellulose-induced differentiation.	Methylcellulose	171-186	nucleophosmin 1	Homo sapiens	15-18
19621982-6	2010	Release and permeation of insulin from the gel formulations decreased with increased concentration of PF-127, presence of salts, and addition of MC and HPMC.	Methylcellulose	145-147	insulin	Homo sapiens	26-33
18203894-9	2008	Insulin IAUC was lower than control (P < 0.001) after meals containing 2 g HV-HPMC, 2 g UHV-HPMC, and 4 g MC.	Methylcellulose	83-85	insulin	Homo sapiens	0-7
19080078-12	2008	The IOD of Muc5ac protein expression by Western-blotting of the methylcellulose group and the 3 YM976 groups were 1.177+/-0.190, 0.806+/-0.180, 0.303+/-0.061, and 0.134+/-0.035 respectively.	Methylcellulose	64-79	mucin 5AC, oligomeric mucus/gel-forming	Rattus norvegicus	11-17
18203894-11	2008	These findings indicate that HV-HPMC (1 and 2 g), UHV-HPMC (2 g), and MC (4 g) consumption reduced postprandial insulin excursions consistent with delayed glucose absorption.	Methylcellulose	34-36	insulin	Homo sapiens	112-119
17692541-4	2007	Using the embryonic stem cells generated for such studies, we show here that the presence of the fusion product AML1-ETO blocks definitive hematopoiesis in vitro as well, in both one and two step methylcellulose methods of embryonic stem cell hematopoietic differentiation.	Methylcellulose	196-211	runt related transcription factor 1	Mus musculus	112-116
17692541-4	2007	Using the embryonic stem cells generated for such studies, we show here that the presence of the fusion product AML1-ETO blocks definitive hematopoiesis in vitro as well, in both one and two step methylcellulose methods of embryonic stem cell hematopoietic differentiation.	Methylcellulose	196-211	RUNX1 translocation partner 1	Mus musculus	117-120
17934235-2	2007	Control animals were treated with a 0.5 w/v% solution of methylcellulose, the vehicle for P40.	Methylcellulose	57-72	septin 3	Rattus norvegicus	90-93
17275811-4	2007	Based on the expression profiles of CD45 and c-Kit, we defined three cell populations: CD45(low) c-Kit(+) cells that had the ability to form hematopoietic cell colonies in methylcellulose media and in co-cultures with stromal cells; CD45(low) c-Kit(-) cells that showed a granulocyte morphology; CD45(high) c-Kit(low/-) that exhibited a macrophage morphology.	Methylcellulose	172-187	protein tyrosine phosphatase, receptor type, C	Mus musculus	87-91
17275811-4	2007	Based on the expression profiles of CD45 and c-Kit, we defined three cell populations: CD45(low) c-Kit(+) cells that had the ability to form hematopoietic cell colonies in methylcellulose media and in co-cultures with stromal cells; CD45(low) c-Kit(-) cells that showed a granulocyte morphology; CD45(high) c-Kit(low/-) that exhibited a macrophage morphology.	Methylcellulose	172-187	KIT proto-oncogene receptor tyrosine kinase	Mus musculus	97-102
17275811-4	2007	Based on the expression profiles of CD45 and c-Kit, we defined three cell populations: CD45(low) c-Kit(+) cells that had the ability to form hematopoietic cell colonies in methylcellulose media and in co-cultures with stromal cells; CD45(low) c-Kit(-) cells that showed a granulocyte morphology; CD45(high) c-Kit(low/-) that exhibited a macrophage morphology.	Methylcellulose	172-187	protein tyrosine phosphatase, receptor type, C	Mus musculus	87-91
17275811-4	2007	Based on the expression profiles of CD45 and c-Kit, we defined three cell populations: CD45(low) c-Kit(+) cells that had the ability to form hematopoietic cell colonies in methylcellulose media and in co-cultures with stromal cells; CD45(low) c-Kit(-) cells that showed a granulocyte morphology; CD45(high) c-Kit(low/-) that exhibited a macrophage morphology.	Methylcellulose	172-187	KIT proto-oncogene receptor tyrosine kinase	Mus musculus	97-102
17275811-4	2007	Based on the expression profiles of CD45 and c-Kit, we defined three cell populations: CD45(low) c-Kit(+) cells that had the ability to form hematopoietic cell colonies in methylcellulose media and in co-cultures with stromal cells; CD45(low) c-Kit(-) cells that showed a granulocyte morphology; CD45(high) c-Kit(low/-) that exhibited a macrophage morphology.	Methylcellulose	172-187	protein tyrosine phosphatase, receptor type, C	Mus musculus	87-91
17275811-4	2007	Based on the expression profiles of CD45 and c-Kit, we defined three cell populations: CD45(low) c-Kit(+) cells that had the ability to form hematopoietic cell colonies in methylcellulose media and in co-cultures with stromal cells; CD45(low) c-Kit(-) cells that showed a granulocyte morphology; CD45(high) c-Kit(low/-) that exhibited a macrophage morphology.	Methylcellulose	172-187	KIT proto-oncogene receptor tyrosine kinase	Mus musculus	97-102
16732331-4	2006	Intriguingly, gadd45a-/- and gadd45b-/- colony forming units granulocyte/macrophage progenitors displayed prolonged proliferation capacity compared to wt controls upon re-plating in methylcellulose supplemented with interleukin-3.	Methylcellulose	182-197	growth arrest and DNA-damage-inducible 45 beta	Mus musculus	29-36
15681438-6	2005	LMP2A inhibited induction of differentiation in an assay conducted with semisolid methylcellulose medium, and the PY motifs were critical for this inhibition.	Methylcellulose	82-97	LMP2A	Human gammaherpesvirus 4	0-5
16643931-5	2006	In methylcellulose (MC) solution with YO-PRO-1 or YOYO-1, linear plasmid DNA eluted first, followed by supercoiled and nicked plasmid DNA, and nicked plasmid DNA eluted as a broad peak.	Methylcellulose	3-18	lamin A/C	Homo sapiens	41-46
16643931-5	2006	In methylcellulose (MC) solution with YO-PRO-1 or YOYO-1, linear plasmid DNA eluted first, followed by supercoiled and nicked plasmid DNA, and nicked plasmid DNA eluted as a broad peak.	Methylcellulose	20-22	lamin A/C	Homo sapiens	41-46
16338489-4	2005	RESULTS: Post ACE transfer, CFU-GM-derived colonies were generated in methylcellulose in the presence or absence of bleomycin.	Methylcellulose	70-85	angiotensin I converting enzyme	Homo sapiens	14-17
16555267-5	2006	We have developed a bioactive scaffold for neural tissue engineering by tethering laminin-1 (LN) to methylcellulose (MC), a thermoresponsive hydrogel.	Methylcellulose	117-119	laminin subunit alpha 1	Rattus norvegicus	82-91
16555267-8	2006	Immunoassays demonstrated tethering of LN at 1.6 +/- 0.5 ng of LN per milligram of MC.	Methylcellulose	83-85	laminin subunit alpha 1	Rattus norvegicus	39-41
16555267-8	2006	Immunoassays demonstrated tethering of LN at 1.6 +/- 0.5 ng of LN per milligram of MC.	Methylcellulose	83-85	laminin subunit alpha 1	Rattus norvegicus	63-65
16555267-9	2006	Rheological measurements for different MC-LN constructs indicated MC composition- and MC treatment-dependent effects on solution-gelation transition temperature.	Methylcellulose	39-41	laminin subunit alpha 1	Rattus norvegicus	42-44
16555267-9	2006	Rheological measurements for different MC-LN constructs indicated MC composition- and MC treatment-dependent effects on solution-gelation transition temperature.	Methylcellulose	66-68	laminin subunit alpha 1	Rattus norvegicus	42-44
16555267-9	2006	Rheological measurements for different MC-LN constructs indicated MC composition- and MC treatment-dependent effects on solution-gelation transition temperature.	Methylcellulose	66-68	laminin subunit alpha 1	Rattus norvegicus	42-44
16555267-10	2006	Cellular assays with primary rat cortical neurons demonstrated enhanced cell adhesion and viability on LN-functionalized MC when compared with base and oxidized MC.	Methylcellulose	121-123	laminin subunit alpha 1	Rattus norvegicus	103-105
12737498-1	2003	PURPOSE: To investigate the effects of 0.5, 1.0 and 2.5% methylcellulose coating agents on the ERG in normals.	Methylcellulose	57-72	ETS transcription factor ERG	Homo sapiens	95-98
15607963-3	2004	MOZ-TIF2-transduced progenitors could be serially replated in methylcellulose cultures and continuously propagated in liquid culture, and resulted in an acute myeloid leukemia in vivo that could be serially transplanted.	Methylcellulose	62-77	K(lysine) acetyltransferase 6A	Mus musculus	0-3
15607963-3	2004	MOZ-TIF2-transduced progenitors could be serially replated in methylcellulose cultures and continuously propagated in liquid culture, and resulted in an acute myeloid leukemia in vivo that could be serially transplanted.	Methylcellulose	62-77	TGF-beta1-induced anti-apoptotic factor 2	Mus musculus	4-8
15203047-1	2004	We developed a novel methylcellulose-immobilized strong cation-exchange (MC-SCX) precolumn for direct analysis of drugs in plasma.	Methylcellulose	21-36	scleraxis bHLH transcription factor	Rattus norvegicus	76-79
15248695-3	2004	At a fixed total salt concentration, the sol-gel transition temperature nicely followed a rule of mixing: Tp = m1Tp1 + m2Tp2 where Tp, Tp1, and Tp2 are the gelation peak temperatures for the MC solutions with a salt mixture, NaCl, and NaI, respectively, and mi is the molar fraction of the salt component i in the salt mixture.	Methylcellulose	191-193	transition protein 2	Homo sapiens	121-124
15631710-15	2004	The results showed that HSC was slowly generated with a few hematopoietic colony formations in methylcellulose medium differentiation system.	Methylcellulose	95-110	fucosyltransferase 1 (H blood group)	Homo sapiens	24-27
11771657-9	2002	Furthermore, the c-peptide (10-100 ng/ml) significantly inhibited early human OCL precursor (granulocyte-macrophage colony-forming unit [GM-CFU]) colony formation in methylcellulose cultures.	Methylcellulose	166-181	insulin	Homo sapiens	17-26
12507899-6	2003	Suspension of KCs in methylcellulose induced p12 expression.	Methylcellulose	21-36	DNA polymerase epsilon 4, accessory subunit	Homo sapiens	45-48
11929803-5	2002	Erythroid progenitors from an affected individual displayed Epo hypersensitivity in in vitro methylcellulose cultures, as indicated by more numerous erythroid burst-forming unit-derived colonies in low Epo concentrations compared to normal controls.	Methylcellulose	93-108	erythropoietin	Homo sapiens	60-63
12016119-3	2002	In normal, conscious unoperated animals, ghrelin/MTLRP (5 or 20 microg/kg iv) significantly accelerated the gastric emptying of a methylcellulose liquid solution (gastric residue after 15 min: 57 +/- 7, 42 +/- 11, 17 +/- 4, and 9 +/- 3% of the ingested meal with doses of 0, 1, 5, and 20 microg/kg iv, respectively) Transit of the methylcellulose liquid solution was also accelerated by ghrelin/MTLRP in the small intestine but not in the colon.	Methylcellulose	130-145	ghrelin and obestatin prepropeptide	Rattus norvegicus	41-48
12016119-3	2002	In normal, conscious unoperated animals, ghrelin/MTLRP (5 or 20 microg/kg iv) significantly accelerated the gastric emptying of a methylcellulose liquid solution (gastric residue after 15 min: 57 +/- 7, 42 +/- 11, 17 +/- 4, and 9 +/- 3% of the ingested meal with doses of 0, 1, 5, and 20 microg/kg iv, respectively) Transit of the methylcellulose liquid solution was also accelerated by ghrelin/MTLRP in the small intestine but not in the colon.	Methylcellulose	130-145	ghrelin and obestatin prepropeptide	Rattus norvegicus	49-54
11146157-7	2000	The effect of Ad-p53 on colony-forming unit granulocyte-macrophage (CFU-GM) and burst-forming unit erythroid (BFU-E) colony formation in methylcellulose was tested on purified CD34(+) and CD34(-) cells to evaluate bone marrow toxicity.	Methylcellulose	137-152	tumor protein p53	Homo sapiens	17-20
11516172-1	2001	Suspension of human epidermal cells in methylcellulose-containing medium induces CYP1A1 by a mechanism requiring functional Ah receptor (AhR).	Methylcellulose	39-54	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	81-87
11516172-1	2001	Suspension of human epidermal cells in methylcellulose-containing medium induces CYP1A1 by a mechanism requiring functional Ah receptor (AhR).	Methylcellulose	39-54	aryl hydrocarbon receptor	Homo sapiens	124-135
11516172-1	2001	Suspension of human epidermal cells in methylcellulose-containing medium induces CYP1A1 by a mechanism requiring functional Ah receptor (AhR).	Methylcellulose	39-54	aryl hydrocarbon receptor	Homo sapiens	137-140
11516172-2	2001	In present work CYP1A1 mRNA was induced in a variety of cultured rat epithelial cells by suspension, but the induction was transient, with CYP1A1 mRNA reaching maximal levels by 5 h and disappearing by 12 h. Though the methylcellulose itself contained no detectable ligand, (a) suspension activated the AhR, as judged by mobility shift assays, (b) the AhR competitive inhibitor alpha-naphthoflavone inhibited suspension-mediated induction, and (c) induction was dependent upon dioxin responsive transcriptional elements in the CYP1A1 promoter.	Methylcellulose	219-234	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	16-22
11290589-3	2001	HOXA10 misexpression profoundly impaired myeloid differentiation with a higher yield of blast cells in liquid culture and a greater than 100-fold increased generation of blast colonies after in vitro expansion or after replating of primary colonies first plated in methylcellulose directly after transduction (P < .01).	Methylcellulose	265-280	homeobox A10	Homo sapiens	0-6
11320899-4	2001	In 36 consecutive patients undergoing a stem cell transplantation, we performed a double-blind placebo-controlled study of 300 micrograms GM-CSF in a 2% methylcellulose gel daily versus a 2% methylcellulose gel alone.	Methylcellulose	153-168	colony stimulating factor 2	Homo sapiens	138-144
10886721-2	2000	In this group of rats (Thy-1 + MC group), many macrophages infiltrated in the lytic mesangium accompanied by rupture of capillary loops at an early stage and stayed with abundant deposition of mesangial matrices until day 35, whereas the proliferative lesions following mesangiolysis almost vanished in the rats treated with anti-thy1-1 antibody alone (Thy-1 group).	Methylcellulose	31-33	Thy-1 cell surface antigen	Rattus norvegicus	353-358
10925312-4	2000	While IL-15 exerted no significant effect on KC proliferation and IL-6 or IL-8 secretion, IL-15 inhibited both anti-Fas and methylcellulose-induced KC apoptosis in vitro.	Methylcellulose	124-139	interleukin 15	Homo sapiens	90-95
10886721-2	2000	In this group of rats (Thy-1 + MC group), many macrophages infiltrated in the lytic mesangium accompanied by rupture of capillary loops at an early stage and stayed with abundant deposition of mesangial matrices until day 35, whereas the proliferative lesions following mesangiolysis almost vanished in the rats treated with anti-thy1-1 antibody alone (Thy-1 group).	Methylcellulose	31-33	Thy-1 cell surface antigen	Rattus norvegicus	330-336
10886721-3	2000	In immunostaining, matrix metalloproteinase (MMP)-9 was expressed along regenerating capillaries of the Thy-1 group and in extracapillary lesions of the Thy-1 + MC group after day 7.	Methylcellulose	161-163	matrix metallopeptidase 9	Rattus norvegicus	19-51
10886721-4	2000	In gelatin zymography, the gelatinolytic band for MMP-9 was expressed much more strongly in the Thy-1 + MC group than in the Thy-1 group at day 3, but it was expressed a little more strongly in the Thy-1 group than in the Thy-1 + MC group at day 7.	Methylcellulose	104-106	matrix metallopeptidase 9	Rattus norvegicus	50-55
10886721-4	2000	In gelatin zymography, the gelatinolytic band for MMP-9 was expressed much more strongly in the Thy-1 + MC group than in the Thy-1 group at day 3, but it was expressed a little more strongly in the Thy-1 group than in the Thy-1 + MC group at day 7.	Methylcellulose	104-106	Thy-1 cell surface antigen	Rattus norvegicus	96-101
10886721-4	2000	In gelatin zymography, the gelatinolytic band for MMP-9 was expressed much more strongly in the Thy-1 + MC group than in the Thy-1 group at day 3, but it was expressed a little more strongly in the Thy-1 group than in the Thy-1 + MC group at day 7.	Methylcellulose	230-232	matrix metallopeptidase 9	Rattus norvegicus	50-55
10886721-4	2000	In gelatin zymography, the gelatinolytic band for MMP-9 was expressed much more strongly in the Thy-1 + MC group than in the Thy-1 group at day 3, but it was expressed a little more strongly in the Thy-1 group than in the Thy-1 + MC group at day 7.	Methylcellulose	230-232	Thy-1 cell surface antigen	Rattus norvegicus	96-101
10886721-5	2000	The bands for an active form of MMP-2 were more strongly expressed in the Thy-1 + MC group than in the Thy-1 group throughout the experimental period.	Methylcellulose	82-84	matrix metallopeptidase 2	Rattus norvegicus	32-37
10886721-5	2000	The bands for an active form of MMP-2 were more strongly expressed in the Thy-1 + MC group than in the Thy-1 group throughout the experimental period.	Methylcellulose	82-84	Thy-1 cell surface antigen	Rattus norvegicus	74-79
10446387-6	1999	When bone marrow cells from normal rats were incubated with recombinant rat IL-5 in medium containing methylcellulose, the colony formation by eosinophilic cells was induced.	Methylcellulose	102-117	interleukin 5	Rattus norvegicus	76-80
11023269-4	2000	To increase the residence time of PTH in the injected area, we used methylcellulose (MC) gel (2% W/V) for a slow-release formulation of PTH.	Methylcellulose	68-83	parathyroid hormone	Rattus norvegicus	34-37
11023269-4	2000	To increase the residence time of PTH in the injected area, we used methylcellulose (MC) gel (2% W/V) for a slow-release formulation of PTH.	Methylcellulose	68-83	parathyroid hormone	Rattus norvegicus	136-139
11023269-4	2000	To increase the residence time of PTH in the injected area, we used methylcellulose (MC) gel (2% W/V) for a slow-release formulation of PTH.	Methylcellulose	85-87	parathyroid hormone	Rattus norvegicus	34-37
11023269-4	2000	To increase the residence time of PTH in the injected area, we used methylcellulose (MC) gel (2% W/V) for a slow-release formulation of PTH.	Methylcellulose	85-87	parathyroid hormone	Rattus norvegicus	136-139
11023269-5	2000	MC gel containing PTH (PTH-MC) continuously released biologically active PTH into the acceptor medium for more than 72 hrs in vitro.	Methylcellulose	0-2	parathyroid hormone	Rattus norvegicus	18-21
11023269-5	2000	MC gel containing PTH (PTH-MC) continuously released biologically active PTH into the acceptor medium for more than 72 hrs in vitro.	Methylcellulose	0-2	parathyroid hormone	Rattus norvegicus	23-29
11023269-5	2000	MC gel containing PTH (PTH-MC) continuously released biologically active PTH into the acceptor medium for more than 72 hrs in vitro.	Methylcellulose	0-2	parathyroid hormone	Rattus norvegicus	23-26
10529595-3	1999	When bone marrow cells from normal rats were incubated with recombinant rat IL-5 in medium containing methylcellulose, the colony formation by eosinophilic cells was induced.	Methylcellulose	102-117	interleukin 5	Rattus norvegicus	76-80
10403792-2	1999	When single undifferentiated EG-1 cells were inoculated directly into the methylcellulose medium, both primitive and definitive erythropoiesis were seen in embryoid bodies derived from the EG cells as observed in ES cells, and production of myeloid cell lineages was stimulated by IL-3.	Methylcellulose	74-89	interleukin 3	Mus musculus	281-285
9950292-7	1999	The formulation containing MC exhibited a lower Tmc than the formulation containing dextran because of the smaller ratio of bound water and the higher molecular mobility of mobile water.	Methylcellulose	27-29	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	48-51
9447833-6	1997	Colony growth of MNC and CD34+ cells was enhanced by the addition of SCF to methylcellulose mixture, resulting in a statistically significant increase in CFU-GM and CFU-GEMM but not in BFU-E numbers.	Methylcellulose	76-91	CD34 molecule	Homo sapiens	25-29
9482885-7	1998	Furthermore, TIAR-deficient embryonic stem cells do not proliferate in the absence of exogenous leukemia inhibitory factor in an in vitro methylcellulose culture assay, supporting a role for TIAR in regulating cell proliferation.	Methylcellulose	138-153	Tia1 cytotoxic granule-associated RNA binding protein-like 1	Mus musculus	13-17
9591327-2	1998	The c-PTIO promoted colony formation by erythropoietin and either interleukin-6 (IL-6) or the c-kit ligand/stem cell factor (SCF) in a methylcellulose culture, where the number of colonies increased 2.2-fold and 1.7-fold, respectively.	Methylcellulose	135-150	kit ligand	Mus musculus	125-128
9447833-6	1997	Colony growth of MNC and CD34+ cells was enhanced by the addition of SCF to methylcellulose mixture, resulting in a statistically significant increase in CFU-GM and CFU-GEMM but not in BFU-E numbers.	Methylcellulose	76-91	KIT ligand	Homo sapiens	69-72
9275711-2	1996	In this paper, the effects of histamine H2 receptor agonist 4-methylhistamine (4-MH) and its antagonist ranitidine (Ranit) on the growth of PB CFU-GM cultured in methylcellulose system were studied and their differential effects on normal PB CFU-GM and leukemic HL-60 cells were compared with the effect of the antineoplastic agent cytosine arabinoside (Ara-C).	Methylcellulose	162-177	histamine receptor H2	Homo sapiens	30-51
9354659-3	1997	When Sca-1+c-kit+ fetal liver cells were cultured in methylcellulose media with interleukin (IL)-2, IL-7, IL-11, and steel factor (SF), we found mixed colonies consisting of diffuse small round cells characteristic of immature NK cells and other types of cells.	Methylcellulose	53-68	ataxin 1	Mus musculus	5-10
9358767-3	1997	Therefore, we applied 0.7 to 0.9 microgram of VEGF via methylcellulose carriers into the midbrain or onto the right forelimb of 4.5-day-old quail embryos.	Methylcellulose	55-70	vascular endothelial growth factor A	Mus musculus	46-50
9170212-4	1997	Addition of SCF (50 ng/ml) to methyl-cellulose cultures stimulated with maximal concentrations of G-CSF, GM-CSF, interleukin 3 and erythropoietin significantly increased the growth (mean +/- SE) of CFU-Mix (7.7 +/- 1.7 versus 2.4 +/- 0.6, p < or = 0.0001), BFU-E (47 +/- 10 versus 32 +/- 6, p < or = 0.002) and CFU-GM (173 +/- 31 versus 112 +/- 20, p < or = 0.0001).	Methylcellulose	30-46	KIT ligand	Homo sapiens	12-15
9170212-4	1997	Addition of SCF (50 ng/ml) to methyl-cellulose cultures stimulated with maximal concentrations of G-CSF, GM-CSF, interleukin 3 and erythropoietin significantly increased the growth (mean +/- SE) of CFU-Mix (7.7 +/- 1.7 versus 2.4 +/- 0.6, p < or = 0.0001), BFU-E (47 +/- 10 versus 32 +/- 6, p < or = 0.002) and CFU-GM (173 +/- 31 versus 112 +/- 20, p < or = 0.0001).	Methylcellulose	30-46	colony stimulating factor 3	Homo sapiens	98-103
9170212-4	1997	Addition of SCF (50 ng/ml) to methyl-cellulose cultures stimulated with maximal concentrations of G-CSF, GM-CSF, interleukin 3 and erythropoietin significantly increased the growth (mean +/- SE) of CFU-Mix (7.7 +/- 1.7 versus 2.4 +/- 0.6, p < or = 0.0001), BFU-E (47 +/- 10 versus 32 +/- 6, p < or = 0.002) and CFU-GM (173 +/- 31 versus 112 +/- 20, p < or = 0.0001).	Methylcellulose	30-46	colony stimulating factor 2	Homo sapiens	105-111
9170212-4	1997	Addition of SCF (50 ng/ml) to methyl-cellulose cultures stimulated with maximal concentrations of G-CSF, GM-CSF, interleukin 3 and erythropoietin significantly increased the growth (mean +/- SE) of CFU-Mix (7.7 +/- 1.7 versus 2.4 +/- 0.6, p < or = 0.0001), BFU-E (47 +/- 10 versus 32 +/- 6, p < or = 0.002) and CFU-GM (173 +/- 31 versus 112 +/- 20, p < or = 0.0001).	Methylcellulose	30-46	interleukin 3	Homo sapiens	113-126
9170212-4	1997	Addition of SCF (50 ng/ml) to methyl-cellulose cultures stimulated with maximal concentrations of G-CSF, GM-CSF, interleukin 3 and erythropoietin significantly increased the growth (mean +/- SE) of CFU-Mix (7.7 +/- 1.7 versus 2.4 +/- 0.6, p < or = 0.0001), BFU-E (47 +/- 10 versus 32 +/- 6, p < or = 0.002) and CFU-GM (173 +/- 31 versus 112 +/- 20, p < or = 0.0001).	Methylcellulose	30-46	erythropoietin	Homo sapiens	131-145
9354659-3	1997	When Sca-1+c-kit+ fetal liver cells were cultured in methylcellulose media with interleukin (IL)-2, IL-7, IL-11, and steel factor (SF), we found mixed colonies consisting of diffuse small round cells characteristic of immature NK cells and other types of cells.	Methylcellulose	53-68	kit ligand	Mus musculus	117-129
9192789-4	1997	Hypersensitivity to Epo of erythroid progenitors from an affected individual was observed in in vitro methylcellulose cultures, as indicated by more numerous and larger colonies compared with those of a control subject.	Methylcellulose	102-117	erythropoietin	Mus musculus	20-23
8977240-7	1996	Tpo added to SCF + erythropoietin (Epo)-supplemented methylcellulose cultures potently enhanced the formation of multilineage colonies containing granulocytes, macrophages, erythrocytes, and Mks.	Methylcellulose	53-68	thrombopoietin	Mus musculus	0-3
8977240-7	1996	Tpo added to SCF + erythropoietin (Epo)-supplemented methylcellulose cultures potently enhanced the formation of multilineage colonies containing granulocytes, macrophages, erythrocytes, and Mks.	Methylcellulose	53-68	erythropoietin	Mus musculus	19-33
8977240-7	1996	Tpo added to SCF + erythropoietin (Epo)-supplemented methylcellulose cultures potently enhanced the formation of multilineage colonies containing granulocytes, macrophages, erythrocytes, and Mks.	Methylcellulose	53-68	erythropoietin	Mus musculus	35-38
8879210-6	1996	IL-10 significantly inhibited the spontaneous growth of myeloid colonies in methylcellulose in 10/11 patients, and autonomous CMML cell growth in suspension in 5/5 patients tested.	Methylcellulose	76-91	interleukin 10	Homo sapiens	0-5
1712223-3	1991	While rIL-4 by itself did not show any colony stimulatory activity in the blast colony assay, it suppressed the blast colony formation in methylcellulose stimulated with G-CSF, GM-CSF or IL-3 in 14 patients.	Methylcellulose	138-153	interleukin 4	Rattus norvegicus	6-11
7633846-8	1995	CD34-enriched cells were infected with viral vectors bearing gamma c and grown in methylcellulose media.	Methylcellulose	82-97	CD34 antigen	Mus musculus	0-4
1790712-4	1991	EGF in PBS or in MC in doses ranging from 2-100 micrograms/eye did not promote more complete wound healing than that seen in eyes treated with their respective vehicle solutions alone.	Methylcellulose	17-19	epidermal growth factor	Homo sapiens	0-3
1655816-4	1991	In both of the two cases, IL-3 stimulated leukemic colony formation in methylcellulose culture, whereas IL-6 showed little such activity.	Methylcellulose	71-86	interleukin 3	Homo sapiens	26-30
7528591-2	1994	In the presence of human interleukin 3 (IL-3) and stem cell factor (SCF), the growth of colony forming units for granulocyte/macrophage (CFU-GM) in serum-free methylcellulose culture was enhanced up to 5.5-fold over baseline colony formation (n = 10, mean +/- SE, 3.18 +/- 1.00) by coculture with 2.5 x 10(3) U/ml IFN-gamma, whereas burst forming units-erythroid (BFU-E) growth induced by additional erythropoietin (Epo) was reduced dose-dependently.	Methylcellulose	159-174	interleukin 3	Homo sapiens	25-44
7528591-2	1994	In the presence of human interleukin 3 (IL-3) and stem cell factor (SCF), the growth of colony forming units for granulocyte/macrophage (CFU-GM) in serum-free methylcellulose culture was enhanced up to 5.5-fold over baseline colony formation (n = 10, mean +/- SE, 3.18 +/- 1.00) by coculture with 2.5 x 10(3) U/ml IFN-gamma, whereas burst forming units-erythroid (BFU-E) growth induced by additional erythropoietin (Epo) was reduced dose-dependently.	Methylcellulose	159-174	KIT ligand	Homo sapiens	50-66
7528591-2	1994	In the presence of human interleukin 3 (IL-3) and stem cell factor (SCF), the growth of colony forming units for granulocyte/macrophage (CFU-GM) in serum-free methylcellulose culture was enhanced up to 5.5-fold over baseline colony formation (n = 10, mean +/- SE, 3.18 +/- 1.00) by coculture with 2.5 x 10(3) U/ml IFN-gamma, whereas burst forming units-erythroid (BFU-E) growth induced by additional erythropoietin (Epo) was reduced dose-dependently.	Methylcellulose	159-174	KIT ligand	Homo sapiens	68-71
7680241-5	1993	Liquid-suspension preincubation of blood cells with FK506 before culture in methylcellulose induced a significant increase in the amount of IL-3-supported growth of CFU-GM and BFU-E, whereas initial preincubation with IL-3 and subsequent culture with FK506 plus IL-3 exerted its stimulatory effect only on BFU-E.	Methylcellulose	76-91	interleukin 3	Homo sapiens	140-144
8492450-4	1993	Eo-CSF is generally determined by colony formation methods, such as the methylcellulose method or liquid culture method.	Methylcellulose	72-87	colony stimulating factor 2	Homo sapiens	3-6
1712223-3	1991	While rIL-4 by itself did not show any colony stimulatory activity in the blast colony assay, it suppressed the blast colony formation in methylcellulose stimulated with G-CSF, GM-CSF or IL-3 in 14 patients.	Methylcellulose	138-153	colony stimulating factor 3	Homo sapiens	170-175
2127699-3	1990	Cells arrested in the presence of serum by anchorage denial in methyl cellulose suspension culture also induced vinculin expression and formed large vinculin positive plaques when reattaching and spreading on the substrate in the presence of serum.	Methylcellulose	63-79	vinculin	Homo sapiens	112-120
2127699-3	1990	Cells arrested in the presence of serum by anchorage denial in methyl cellulose suspension culture also induced vinculin expression and formed large vinculin positive plaques when reattaching and spreading on the substrate in the presence of serum.	Methylcellulose	63-79	vinculin	Homo sapiens	149-157
35335708-2	2022	To overcome this obstacle, we developed a novel, completely solvent-free process to prepare mechanically robust CNF-reinforced silica nanocomposites via the incorporation of methylcellulose and starch.	Methylcellulose	174-189	NPHS1 adhesion molecule, nephrin	Homo sapiens	112-115
2096963-1	1990	The formulation for the controlled release of NaF from matrix tablets using Methyl cellulose to prepare chewable NaF tablets for the prevention of dental caries is developed.	Methylcellulose	76-92	C-X-C motif chemokine ligand 8	Homo sapiens	46-49
2096963-1	1990	The formulation for the controlled release of NaF from matrix tablets using Methyl cellulose to prepare chewable NaF tablets for the prevention of dental caries is developed.	Methylcellulose	76-92	C-X-C motif chemokine ligand 8	Homo sapiens	113-116
34834177-8	2021	Thus, FGF-2 solution is effectively stabilised against both thermal and processing stressors in the presence of MC and alanine (F5), or MC and HSA (F6).	Methylcellulose	112-114	fibroblast growth factor 2	Homo sapiens	6-11
34834177-8	2021	Thus, FGF-2 solution is effectively stabilised against both thermal and processing stressors in the presence of MC and alanine (F5), or MC and HSA (F6).	Methylcellulose	136-138	fibroblast growth factor 2	Homo sapiens	6-11
2874894-2	1986	T-Cell-independent B-cell tolerance to the hapten derivatives of carboxymethyl cellulose (CMC) or methyl cellulose (MC) appears to be controlled by Thy-1-, Ly-2- adherent (A) cells contained in the spleen or peritoneal fluid.	Methylcellulose	72-88	thymus cell antigen 1, theta	Mus musculus	148-153
2532859-2	1989	Incubation with dCF (10(-5)M) and dAdo (10(-4)M) for 18 hours, inhibited protein and RNA synthesis in unstimulated lymphocytes and impaired the ability of the cells to respond to PHA stimulation or to give rise to T-cell colonies in methyl-cellulose.	Methylcellulose	233-249	ado	Drosophila melanogaster	34-38
3181342-2	1988	All cell lines (K562, HL-60, JOK-1, Daudi, and BB3, an IgM-kappa B-cell line) showed a prominent decrease in colony numbers and remarkable changes in colony morphology at rising MC concentrations, whereas no such influence could be demonstrated for HCL, mixed lineage colony-forming units (CFU-GEMM), granulocyte-macrophage CFU (CFU-GM), erythroid burst-forming units (BFU-E), and erythroid CFU (CFU-E).	Methylcellulose	178-180	bombesin receptor subtype 3	Homo sapiens	47-50
3260000-0	1988	Effects of recombinant G-CSF and GM-CSF on the growth in methylcellulose and suspension of the blast cells in acute myeloblastic leukemia.	Methylcellulose	57-72	colony stimulating factor 3	Homo sapiens	23-28
3260000-0	1988	Effects of recombinant G-CSF and GM-CSF on the growth in methylcellulose and suspension of the blast cells in acute myeloblastic leukemia.	Methylcellulose	57-72	colony stimulating factor 2	Homo sapiens	33-39
3416076-2	1988	When PMC purified to greater than 99% purity were cultured in methylcellulose with IL-3 and IL-4, approximately 25% of the PMC formed colonies, all of which contained both berberine sulfate-positive and berberine sulfate-negative mast cells.	Methylcellulose	62-77	interleukin 3	Mus musculus	83-87
3136661-5	1988	Intravenous injection of CCK-8 (300 pmol) 5 min before intragastric administration of a methylcellulose solution decreased gastric emptying by 55% in conscious control or vehicle-treated rats.	Methylcellulose	88-103	cholecystokinin	Rattus norvegicus	25-28
3042283-7	1988	When applied in methylcellulose-based eye drops, 90% of the EGF was lost from tear film within 10 min, while a small amount (10%) remained associated with conjuctival tissue.	Methylcellulose	16-31	epidermal growth factor	Homo sapiens	60-63
3487359-2	1986	First, both GM-CSF and HTB9-CM stimulated blast colony formation in methylcellulose cultures, patient-to-patient variations were seen in the dose-response curves, and GM-CSF was effective, but less so that HTB9-CM.	Methylcellulose	68-83	colony stimulating factor 2	Homo sapiens	12-18
2874894-2	1986	T-Cell-independent B-cell tolerance to the hapten derivatives of carboxymethyl cellulose (CMC) or methyl cellulose (MC) appears to be controlled by Thy-1-, Ly-2- adherent (A) cells contained in the spleen or peritoneal fluid.	Methylcellulose	72-88	CD8 antigen, alpha chain	Mus musculus	156-160
2874894-2	1986	T-Cell-independent B-cell tolerance to the hapten derivatives of carboxymethyl cellulose (CMC) or methyl cellulose (MC) appears to be controlled by Thy-1-, Ly-2- adherent (A) cells contained in the spleen or peritoneal fluid.	Methylcellulose	91-93	thymus cell antigen 1, theta	Mus musculus	148-153
2874894-2	1986	T-Cell-independent B-cell tolerance to the hapten derivatives of carboxymethyl cellulose (CMC) or methyl cellulose (MC) appears to be controlled by Thy-1-, Ly-2- adherent (A) cells contained in the spleen or peritoneal fluid.	Methylcellulose	91-93	CD8 antigen, alpha chain	Mus musculus	156-160
6718364-0	1984	The effect of methylcellulose on extrarenal erythropoietin production.	Methylcellulose	14-29	erythropoietin	Rattus norvegicus	44-58
3877534-2	1985	Delay for up to 72 hours of the addition of erythropoietin to semi-solid methylcellulose cultures of concentrated peripheral blood progenitors minimizes or eliminates BPA-independent erythroid colony formation with little loss of BPA-dependent erythroid colony formation.	Methylcellulose	73-88	erythropoietin	Homo sapiens	44-58
3906679-3	1985	From solutions of dextran, carboxymethylcellulose, hydroxyethylcellulose, and polyvinylpyrrolidone the release of GnRH is prolonged whereas the release of GnRH from highly viscous solutions of methylcellulose and polyacrylic acid is not.	Methylcellulose	34-49	gonadotropin releasing hormone 1	Homo sapiens	114-118
3874848-1	1985	Radiation survival of MOLT-4, a leukaemic T-lymphocyte cell line, was measured by counting colonies formed in 0.8 per cent methyl cellulose.	Methylcellulose	123-139	transmembrane protein 132D	Homo sapiens	22-26
444656-0	1979	In vitro assay for erythropoietin: erythroid colony formation in methyl cellulose used for the measurement of erythropoietin in plasma.	Methylcellulose	65-81	erythropoietin	Mus musculus	19-33
7373218-1	1980	We investigated the effects of murine resident peritoneal macrophages on the in vitro proliferation of erythropoietin (Ep)-sensitive committed precursors colony-forming unit-erythroid (CFU-E) and burst-forming unit-erythroid (BFU-E) with a two-layer cloning system of methylcellulose and semisolid agar.	Methylcellulose	268-283	erythropoietin	Mus musculus	103-117
7072710-1	1982	A quantitative bioassay for serum erythropoietin in anemic patients was established with erythroid colony-forming technique using methyl cellulose.	Methylcellulose	130-146	erythropoietin	Homo sapiens	34-48
444656-0	1979	In vitro assay for erythropoietin: erythroid colony formation in methyl cellulose used for the measurement of erythropoietin in plasma.	Methylcellulose	65-81	erythropoietin	Mus musculus	110-124
444656-1	1979	Erythroid colony formation in methyl cellulose has been used for the measurement of erythropoietin in plasma.	Methylcellulose	30-46	erythropoietin	Mus musculus	84-98
987043-1	1976	A time course study of the sequential appearance of erythropoietin-dependent colonies and bursts (derived from CFU-E and BFU-E, respectively) was performed on mouse hemopoietic cells cultured in methyl cellulose containing 2-mercaptoethanol.	Methylcellulose	195-211	erythropoietin	Mus musculus	52-66
435647-1	1979	We have demonstrated that the cyclohexanone method for the extraction of hematin can be used to measure hemoglobin synthesis induced by erythropoietin (epo) in mouse bone marrow cells cultured in medium containing methyl cellulose.	Methylcellulose	214-230	erythropoietin	Mus musculus	136-150
435647-1	1979	We have demonstrated that the cyclohexanone method for the extraction of hematin can be used to measure hemoglobin synthesis induced by erythropoietin (epo) in mouse bone marrow cells cultured in medium containing methyl cellulose.	Methylcellulose	214-230	erythropoietin	Mus musculus	152-155
286333-7	1979	Cells from the livers of midtrimester fetuses were cultured in methylcellulose with erythropoietin.	Methylcellulose	63-78	erythropoietin	Homo sapiens	84-98
32414848-5	2021	Incubation of KMT2A-R ALL cells in vitro with entospletinib inhibited methylcellulose colony formation and SYK pathway signaling in a dose-dependent manner.	Methylcellulose	70-85	lysine methyltransferase 2A	Homo sapiens	14-25
30705588-0	2019	An anti-inflammatory peptide and brain-derived neurotrophic factor-modified hyaluronan-methylcellulose hydrogel promotes nerve regeneration in rats with spinal cord injury.	Methylcellulose	87-102	brain-derived neurotrophic factor	Rattus norvegicus	33-66
32942681-5	2020	Inhibition of SMS2 activity significantly decreased sperm motility and penetration ability into methylcellulose, but had no influence on capacitation and acrosome reaction, or on intracellular [Ca2+]i compared to IgG-treated control groups.	Methylcellulose	96-111	sphingomyelin synthase 2	Homo sapiens	14-18
32942681-7	2020	Taken together, SMS2 can affect sperm motility and penetration ability into methylcellulose, and participate in apoptosis associated with the Akt and ERK signaling pathways.	Methylcellulose	76-91	sphingomyelin synthase 2	Homo sapiens	16-20
29211290-10	2017	The mRNA level of BSP has increased significantly in MTA with MC/CaCl2 compared to the control (p<.05).	Methylcellulose	62-64	integrin binding sialoprotein	Homo sapiens	18-21
29687380-7	2018	This solution exhibited a gel formation temperature of ~32  C. The addition (evenly spread) of 1 ml of 3 mg/ml rat tail type-I (pH adjusted to 7.5) over the MC coated surface at 37  C improves ASC adhesion and proliferation on the methylcellulose system.	Methylcellulose	157-159	PYD and CARD domain containing	Rattus norvegicus	193-196
29687380-8	2018	Upon confluence, a continuous monolayer ASC sheet was formed on the surface of the MC hydrogel system.	Methylcellulose	83-85	PYD and CARD domain containing	Rattus norvegicus	40-43
29146910-5	2017	Specific disruption of this protein complex, either genetically or chemically, removed ABCC4 from the plasma membrane, increased drug sensitivity, and abrogated MPP1-dependent hematopoietic progenitor cell replating in methylcellulose.	Methylcellulose	219-234	ATP binding cassette subfamily C member 4	Homo sapiens	87-92
29146910-5	2017	Specific disruption of this protein complex, either genetically or chemically, removed ABCC4 from the plasma membrane, increased drug sensitivity, and abrogated MPP1-dependent hematopoietic progenitor cell replating in methylcellulose.	Methylcellulose	219-234	MAGUK p55 scaffold protein 1	Homo sapiens	161-165
29211290-11	2017	This study revealed higher expression of ALP and mineralization in cells exposed to MTA mixed with water and MTA mixed with MC/CaCl2 compared to the control (p<.05).	Methylcellulose	124-126	alkaline phosphatase, placental	Homo sapiens	41-44
28199020-6	2017	We observed that gem-fed Cln2(-/-) mice lived longer by more than 10 weeks and had better motor activity compared to vehicle (0.1% Methyl cellulose) treatment.	Methylcellulose	131-147	tripeptidyl peptidase I	Mus musculus	25-29
28754385-5	2017	RESULTS: Although at high KCl concentrations (150mM), actin filaments tended to dissociate from a myosin-coated surface, 1% MC prevented this dissociation and enabled filament movement on myosin molecules.	Methylcellulose	124-126	myosin heavy chain 14	Homo sapiens	188-194
28617871-8	2017	Human oral keratinocyte (NOK) and gingival epithelial (hGET) cells induced to differentiate by incubation with either methyl cellulose or growth in organotypic culture accumulated both HIF-1alpha and Blimp-1alpha, another cellular factor implicated in lytic reactivation.	Methylcellulose	118-134	hypoxia inducible factor 1 subunit alpha	Homo sapiens	185-195
29089758-0	2017	Light-triggered methylcellulose gold nanoparticle hydrogels for leptin release to inhibit fat stores in adipocytes.	Methylcellulose	16-31	leptin	Homo sapiens	64-70
29089758-5	2017	The incorporation of gold NP into MC hydrogels led to a tunable light irradiation response that dictated the hydrogel release rate of leptin.	Methylcellulose	34-36	leptin	Homo sapiens	134-140
28130868-7	2017	OCN was upregulated in MC cell sheets at day 14 and PNIPAAm cell sheets at days 14 and 21.	Methylcellulose	23-25	bone gamma-carboxyglutamate protein	Homo sapiens	0-3
28179525-7	2017	Furthermore, we found that differentiation of NOKs-Akata cells by either methylcellulose suspension or organotypic culture induces LMP1 expression prior to Z and R expression.	Methylcellulose	73-88	PDZ and LIM domain 7	Homo sapiens	131-135
26748668-4	2016	Here, methylcellulose biopolymers are used as mechanical adjuvants to overcome this limitation and generate a thermoresponsive mucin/methylcellulose hybrid system.	Methylcellulose	6-21	LOC100508689	Homo sapiens	127-132
27957280-12	2016	Additionally, the dilution of PTH 1-34 within methyl cellulose (MC) gel increased the time range for drug release, enabling to reduce the drug concentration without decreasing the effectiveness of tooth movement.	Methylcellulose	46-62	parathyroid hormone	Rattus norvegicus	30-35
32263813-6	2016	A highly versatile injectable biomaterial platform for the sustained delivery of BDNF was developed using a physical blend of hyaluronic acid (HA) and methylcellulose (MC), in combination with poly-lactic-co-glycolic acid (PLGA) microparticles.	Methylcellulose	151-166	brain derived neurotrophic factor	Homo sapiens	81-85
32263813-6	2016	A highly versatile injectable biomaterial platform for the sustained delivery of BDNF was developed using a physical blend of hyaluronic acid (HA) and methylcellulose (MC), in combination with poly-lactic-co-glycolic acid (PLGA) microparticles.	Methylcellulose	168-170	brain derived neurotrophic factor	Homo sapiens	81-85
27503502-8	2016	Moreover, megakaryoblastic leukemia 1 (MKL1), a well-known actor in mechanotransduction, was found to be preferentially relocated within the nucleus of MC-differentiated MKs, whereas its inhibition prevented MC-mediated increased proplatelet formation.	Methylcellulose	152-154	myocardin related transcription factor A	Mus musculus	10-37
27503502-8	2016	Moreover, megakaryoblastic leukemia 1 (MKL1), a well-known actor in mechanotransduction, was found to be preferentially relocated within the nucleus of MC-differentiated MKs, whereas its inhibition prevented MC-mediated increased proplatelet formation.	Methylcellulose	152-154	myocardin related transcription factor A	Mus musculus	39-43
27503502-8	2016	Moreover, megakaryoblastic leukemia 1 (MKL1), a well-known actor in mechanotransduction, was found to be preferentially relocated within the nucleus of MC-differentiated MKs, whereas its inhibition prevented MC-mediated increased proplatelet formation.	Methylcellulose	208-210	myocardin related transcription factor A	Mus musculus	10-37
27503502-8	2016	Moreover, megakaryoblastic leukemia 1 (MKL1), a well-known actor in mechanotransduction, was found to be preferentially relocated within the nucleus of MC-differentiated MKs, whereas its inhibition prevented MC-mediated increased proplatelet formation.	Methylcellulose	208-210	myocardin related transcription factor A	Mus musculus	39-43
27083805-5	2016	However at concentrations above CAC, hydrophobic forces operative between MC and gemini surfactants were found to be more for 16-6-16 than that of 16-5-16 and 16-4-16.	Methylcellulose	74-76	carbonic anhydrase 2	Homo sapiens	32-35
25312704-6	2014	The free fatty acids released after 120 min of lipase digestion were 46, 63, and 81% (w/w) for methyl cellulose, pectin, and chitosan, respectively (3.6% (w/w) initial polysaccharide), indicating that methyl cellulose had the highest capacity to inhibit lipid digestion, followed by pectin, and then chitosan.	Methylcellulose	95-111	lipase	Zea mays	47-53
26762290-5	2016	A blend of hyaluronan and methylcellulose, known to promote cell survival, was covalently modified with Src homology 3 (SH3)-binding peptides and demonstrated tunable, affinity-based release of the prosurvival fusion protein SH3-IGF-1.	Methylcellulose	26-41	insulin like growth factor 1	Homo sapiens	229-234
25968649-6	2015	Mutants in fliH and fliI were incapable of translational motion in 1% methylcellulose or soft agar.	Methylcellulose	70-85	flightless I actin binding protein	Mus musculus	20-24
25312704-6	2014	The free fatty acids released after 120 min of lipase digestion were 46, 63, and 81% (w/w) for methyl cellulose, pectin, and chitosan, respectively (3.6% (w/w) initial polysaccharide), indicating that methyl cellulose had the highest capacity to inhibit lipid digestion, followed by pectin, and then chitosan.	Methylcellulose	201-217	lipase	Zea mays	47-53
25245775-0	2014	Thermo-reversible injectable gel based on enzymatically-chopped low molecular weight methylcellulose for exenatide and FGF 21 delivery to treat types 1 and 2 diabetes.	Methylcellulose	85-100	fibroblast growth factor 21	Homo sapiens	119-125
23294516-6	2013	RESULTS: hIgE secretion was induced by IL-4 and inhibited by the IL-4 antagonist Pitrakinra in vivo when formulated with methylcellulose.	Methylcellulose	121-136	immunoglobulin heavy constant epsilon	Homo sapiens	9-13
23513221-5	2013	Methylcellulose colony formation assays further showed that fenretinide significantly suppressed the formation of colonies derived from AML CD34(+) cells but not those from normal CD34(+) cells.	Methylcellulose	0-15	CD34 molecule	Homo sapiens	140-144
24906078-3	2014	Flow cytometry analyses and cultures in methyl cellulose revealed that bone marrow (BM) from CD18(HYP) mice was enriched in hematopoietic precursors, mainly early quiescent short-term and long-term Hematopoietic progenitors cells.	Methylcellulose	40-56	integrin beta 2	Mus musculus	93-97
23294516-6	2013	RESULTS: hIgE secretion was induced by IL-4 and inhibited by the IL-4 antagonist Pitrakinra in vivo when formulated with methylcellulose.	Methylcellulose	121-136	interleukin 4	Homo sapiens	65-69
23294516-6	2013	RESULTS: hIgE secretion was induced by IL-4 and inhibited by the IL-4 antagonist Pitrakinra in vivo when formulated with methylcellulose.	Methylcellulose	121-136	interleukin 4	Homo sapiens	81-91
22884434-4	2012	It was observed that when 0.1 M sodium citrate (NaC) and 0.1 M sodium tartrate (NaT) were used separately, the gelation temperature of MC was reduced up to 44 C and 47 C respectively but when mixture of NaC and NaT (0.1 (M) NaC and 0.1 (M) (NaT)) were used the gelation temperature was further reduced to 36 C. It was clear from ESEM images that when NaC and NaT were used separately the formation of network was not distinguishable.	Methylcellulose	135-137	synuclein alpha	Homo sapiens	48-51
22884434-4	2012	It was observed that when 0.1 M sodium citrate (NaC) and 0.1 M sodium tartrate (NaT) were used separately, the gelation temperature of MC was reduced up to 44 C and 47 C respectively but when mixture of NaC and NaT (0.1 (M) NaC and 0.1 (M) (NaT)) were used the gelation temperature was further reduced to 36 C. It was clear from ESEM images that when NaC and NaT were used separately the formation of network was not distinguishable.	Methylcellulose	135-137	bromodomain containing 2	Homo sapiens	80-83
22884434-4	2012	It was observed that when 0.1 M sodium citrate (NaC) and 0.1 M sodium tartrate (NaT) were used separately, the gelation temperature of MC was reduced up to 44 C and 47 C respectively but when mixture of NaC and NaT (0.1 (M) NaC and 0.1 (M) (NaT)) were used the gelation temperature was further reduced to 36 C. It was clear from ESEM images that when NaC and NaT were used separately the formation of network was not distinguishable.	Methylcellulose	135-137	synuclein alpha	Homo sapiens	203-206
22884434-4	2012	It was observed that when 0.1 M sodium citrate (NaC) and 0.1 M sodium tartrate (NaT) were used separately, the gelation temperature of MC was reduced up to 44 C and 47 C respectively but when mixture of NaC and NaT (0.1 (M) NaC and 0.1 (M) (NaT)) were used the gelation temperature was further reduced to 36 C. It was clear from ESEM images that when NaC and NaT were used separately the formation of network was not distinguishable.	Methylcellulose	135-137	bromodomain containing 2	Homo sapiens	211-214
22884434-4	2012	It was observed that when 0.1 M sodium citrate (NaC) and 0.1 M sodium tartrate (NaT) were used separately, the gelation temperature of MC was reduced up to 44 C and 47 C respectively but when mixture of NaC and NaT (0.1 (M) NaC and 0.1 (M) (NaT)) were used the gelation temperature was further reduced to 36 C. It was clear from ESEM images that when NaC and NaT were used separately the formation of network was not distinguishable.	Methylcellulose	135-137	synuclein alpha	Homo sapiens	203-206
22884434-4	2012	It was observed that when 0.1 M sodium citrate (NaC) and 0.1 M sodium tartrate (NaT) were used separately, the gelation temperature of MC was reduced up to 44 C and 47 C respectively but when mixture of NaC and NaT (0.1 (M) NaC and 0.1 (M) (NaT)) were used the gelation temperature was further reduced to 36 C. It was clear from ESEM images that when NaC and NaT were used separately the formation of network was not distinguishable.	Methylcellulose	135-137	bromodomain containing 2	Homo sapiens	211-214
22884434-4	2012	It was observed that when 0.1 M sodium citrate (NaC) and 0.1 M sodium tartrate (NaT) were used separately, the gelation temperature of MC was reduced up to 44 C and 47 C respectively but when mixture of NaC and NaT (0.1 (M) NaC and 0.1 (M) (NaT)) were used the gelation temperature was further reduced to 36 C. It was clear from ESEM images that when NaC and NaT were used separately the formation of network was not distinguishable.	Methylcellulose	135-137	synuclein alpha	Homo sapiens	203-206
22884434-4	2012	It was observed that when 0.1 M sodium citrate (NaC) and 0.1 M sodium tartrate (NaT) were used separately, the gelation temperature of MC was reduced up to 44 C and 47 C respectively but when mixture of NaC and NaT (0.1 (M) NaC and 0.1 (M) (NaT)) were used the gelation temperature was further reduced to 36 C. It was clear from ESEM images that when NaC and NaT were used separately the formation of network was not distinguishable.	Methylcellulose	135-137	bromodomain containing 2	Homo sapiens	211-214