PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
17354266-9	2007	EDAR is activated by its ligand, ectodysplasin, and uses EDARADD to build an intracellular complex and activate nuclear factor kappa B (NF-kB).	edaradd	57-64	ectodysplasin A receptor	Homo sapiens	0-4
16251197-4	2005	To gain further insight into the mechanism of IKK activation by Edar and Edaradd, we performed a yeast two-hybrid screen and isolated TAB2 (TAK1-binding protein 2) as a binding partner of Edaradd.	edaradd	73-80	TGF-beta activated kinase 1 (MAP3K7) binding protein 2	Homo sapiens	140-162
16251197-4	2005	To gain further insight into the mechanism of IKK activation by Edar and Edaradd, we performed a yeast two-hybrid screen and isolated TAB2 (TAK1-binding protein 2) as a binding partner of Edaradd.	edaradd	188-195	ectodysplasin A receptor	Homo sapiens	64-68
16251197-4	2005	To gain further insight into the mechanism of IKK activation by Edar and Edaradd, we performed a yeast two-hybrid screen and isolated TAB2 (TAK1-binding protein 2) as a binding partner of Edaradd.	edaradd	188-195	TGF-beta activated kinase 1 (MAP3K7) binding protein 2	Homo sapiens	140-162
16251197-6	2005	Here, we show that endogenous and overexpressed TAB2, TRAF6 and TAK1 co-immunoprecipitated with Edaradd in 293 cells.	edaradd	96-103	LOC222344	Homo sapiens	54-59
16251197-6	2005	Here, we show that endogenous and overexpressed TAB2, TRAF6 and TAK1 co-immunoprecipitated with Edaradd in 293 cells.	edaradd	96-103	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	64-68
16251197-7	2005	Moreover, we show that dominant negative forms of TAB2, TRAF6 and TAK1 blocked the NF-kappaB activation induced by Edaradd.	edaradd	115-122	LOC222344	Homo sapiens	56-61
16251197-7	2005	Moreover, we show that dominant negative forms of TAB2, TRAF6 and TAK1 blocked the NF-kappaB activation induced by Edaradd.	edaradd	115-122	mitogen-activated protein kinase kinase kinase 7	Homo sapiens	66-70
12351572-5	2002	On the other hand, hypohidrotic/anhidrotic ectodermal dysplasia (HED/EDA) has been ascribed to at least three genes also involved in NF-kappaB activation: ectodysplasin (EDA1), EDA-receptor (EDAR) and EDAR-associated death domain (EDARADD).	edaradd	231-238	ectodysplasin A	Homo sapiens	69-72
12351572-5	2002	On the other hand, hypohidrotic/anhidrotic ectodermal dysplasia (HED/EDA) has been ascribed to at least three genes also involved in NF-kappaB activation: ectodysplasin (EDA1), EDA-receptor (EDAR) and EDAR-associated death domain (EDARADD).	edaradd	231-238	nuclear factor kappa B subunit 1	Homo sapiens	133-142
12351572-5	2002	On the other hand, hypohidrotic/anhidrotic ectodermal dysplasia (HED/EDA) has been ascribed to at least three genes also involved in NF-kappaB activation: ectodysplasin (EDA1), EDA-receptor (EDAR) and EDAR-associated death domain (EDARADD).	edaradd	231-238	ectodysplasin A	Homo sapiens	155-168
12351572-5	2002	On the other hand, hypohidrotic/anhidrotic ectodermal dysplasia (HED/EDA) has been ascribed to at least three genes also involved in NF-kappaB activation: ectodysplasin (EDA1), EDA-receptor (EDAR) and EDAR-associated death domain (EDARADD).	edaradd	231-238	ectodysplasin A	Homo sapiens	170-174
12351572-6	2002	During hair follicle morphogenesis, EDAR is activated by ectodysplasin, and uses EDARADD as an adapter to build a signal transducing complex that leads to NF-kappaB activation.	edaradd	81-88	ectodysplasin A receptor	Homo sapiens	36-40
12351572-6	2002	During hair follicle morphogenesis, EDAR is activated by ectodysplasin, and uses EDARADD as an adapter to build a signal transducing complex that leads to NF-kappaB activation.	edaradd	81-88	nuclear factor kappa B subunit 1	Homo sapiens	155-164
11780064-7	2001	This adapter, which we have called Edaradd (for Edar-associated death domain), interacts with the death domain of Edar and links the receptor to downstream signalling pathways.	edaradd	35-42	ectodysplasin-A receptor	Mus musculus	48-52
27908934-4	2017	Furthermore, we show that in vivo Gata6 stimulates EDA-receptor signaling adaptor Edaradd level and NF-kappaB pathway activation, known to be important for DNA damage repair and stress response in general and for hair follicle growth in particular.	edaradd	82-89	GATA binding protein 6	Mus musculus	34-39
27908934-5	2017	In cultured keratinocytes, Edaradd rescues DNA damage, cell survival, and proliferation of Gata6 knockout cells and restores MCM10 expression.	edaradd	27-34	GATA binding protein 6	Mus musculus	91-96
27908934-5	2017	In cultured keratinocytes, Edaradd rescues DNA damage, cell survival, and proliferation of Gata6 knockout cells and restores MCM10 expression.	edaradd	27-34	minichromosome maintenance 10 replication initiation factor	Mus musculus	125-130