PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
3126485-2	1988	The c-fos gene and genes stimulated by gamma-interferon also are affected by CaPO4-DNA precipitates, but the calcium ionophore A23187 stimulates only c-fos among this group.	capo4	77-82	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	4-9
6573026-8	1983	RNA only from cells which express phenylalanine hydroxylase, such as rat hepatoma cells and MEL cybrids, when introduced into MEL cells by the CaPO4 coprecipitation method, resulted in the permanent activation of the mouse phenylalanine hydroxylase gene.	capo4	143-148	phenylalanine hydroxylase	Rattus norvegicus	34-59
28202848-10	2016	Moreover, induction of IkappaB, ERK, and p38 phosphorylation by TNFalpha and CaPO4 in macrophages was suppressed by puerarin treatments.	capo4	77-82	mitogen-activated protein kinase 1	Mus musculus	32-35
31479773-5	2019	METHODS: The presence of exosomes in human and calcium phosphate (CaPO4)-induced AAA tissues was determined by immunofluorescence staining of CD63 and Alix.	capo4	66-71	CD63 molecule	Homo sapiens	142-146
31479773-5	2019	METHODS: The presence of exosomes in human and calcium phosphate (CaPO4)-induced AAA tissues was determined by immunofluorescence staining of CD63 and Alix.	capo4	66-71	programmed cell death 6 interacting protein	Homo sapiens	151-155
30651000-5	2019	Flow cytometry analysis, immunostaining, and immunoblot analysis showed that exogenous IL-33 increased CD4+Foxp3+ regulatory T cells in spleens, blood, and aortas in periaorta CaPO4-treated mice.	capo4	176-181	interleukin 33	Mus musculus	87-92
29308612-8	2018	RESULTS: Transfection of anti-ADK miR-shRNAs in HEK293T cells using CaPO4 method showed high efficiency.	capo4	68-73	adenosine kinase	Homo sapiens	30-33
27021877-4	2016	A murine macrophage cell line, RAW264.7, was treated with tumor necrosis factor alpha (TNF-alpha) plus CaPO4 and showed a significant increase in matrix metalloproteinase 9 (Mmp9) mRNA and secreted protein expression compared with TNF-alpha alone.	capo4	103-108	matrix metallopeptidase 9	Mus musculus	146-172
27021877-4	2016	A murine macrophage cell line, RAW264.7, was treated with tumor necrosis factor alpha (TNF-alpha) plus CaPO4 and showed a significant increase in matrix metalloproteinase 9 (Mmp9) mRNA and secreted protein expression compared with TNF-alpha alone.	capo4	103-108	matrix metallopeptidase 9	Mus musculus	174-178
27021877-4	2016	A murine macrophage cell line, RAW264.7, was treated with tumor necrosis factor alpha (TNF-alpha) plus CaPO4 and showed a significant increase in matrix metalloproteinase 9 (Mmp9) mRNA and secreted protein expression compared with TNF-alpha alone.	capo4	103-108	tumor necrosis factor	Mus musculus	231-240
27021877-6	2016	Nr1h2 mRNA and protein expression were suppressed by treatment with TNF-alpha plus CaPO4 but were restored by hyperglycemic conditions.	capo4	83-88	nuclear receptor subfamily 1, group H, member 2	Mus musculus	0-5
27021877-7	2016	Activation of Nr1h2 by the antagonist GW3965 during stimulation with TNF-alpha plus CaPO4 mimicked hyperglycemic conditions and inhibited Mmp9 upregulation, whereas the deactivation of Nr1h2 by small interfering RNA (siRNA) under hyperglycemic conditions canceled the suppressive effect and restored Mmp9 expression induced by TNF-alpha plus CaPO4.	capo4	84-89	nuclear receptor subfamily 1, group H, member 2	Mus musculus	14-19
27021877-7	2016	Activation of Nr1h2 by the antagonist GW3965 during stimulation with TNF-alpha plus CaPO4 mimicked hyperglycemic conditions and inhibited Mmp9 upregulation, whereas the deactivation of Nr1h2 by small interfering RNA (siRNA) under hyperglycemic conditions canceled the suppressive effect and restored Mmp9 expression induced by TNF-alpha plus CaPO4.	capo4	84-89	matrix metallopeptidase 9	Mus musculus	138-142
27021877-7	2016	Activation of Nr1h2 by the antagonist GW3965 during stimulation with TNF-alpha plus CaPO4 mimicked hyperglycemic conditions and inhibited Mmp9 upregulation, whereas the deactivation of Nr1h2 by small interfering RNA (siRNA) under hyperglycemic conditions canceled the suppressive effect and restored Mmp9 expression induced by TNF-alpha plus CaPO4.	capo4	342-347	nuclear receptor subfamily 1, group H, member 2	Mus musculus	14-19
27021877-8	2016	Moreover, Nr1h2 activation with GW3965 significantly suppressed CaPO4-induced aneurysm in mice compared with vehicle-injected control mice.	capo4	64-69	nuclear receptor subfamily 1, group H, member 2	Mus musculus	10-15
28202848-10	2016	Moreover, induction of IkappaB, ERK, and p38 phosphorylation by TNFalpha and CaPO4 in macrophages was suppressed by puerarin treatments.	capo4	77-82	mitogen-activated protein kinase 14	Mus musculus	41-44
26496478-5	2015	We used four methods to test and verify the performance of this level-2 PPI network: cross validation, human AAA mRNA chip array comparison, literature mining, and verification in a mouse CaPO4 AAA model.	capo4	188-193	AAA1	Homo sapiens	194-197
34465809-5	2021	Transgenic overexpression of the human KAL gene (KS-Tg) or administration of recombinant human KAL (rhKAL) inhibited AAA in the calcium phosphate (CaPO4) and subcutaneous angiotensin II (AngII) infusion mouse models.	capo4	147-152	serpin family A member 4	Homo sapiens	39-42
34465809-5	2021	Transgenic overexpression of the human KAL gene (KS-Tg) or administration of recombinant human KAL (rhKAL) inhibited AAA in the calcium phosphate (CaPO4) and subcutaneous angiotensin II (AngII) infusion mouse models.	capo4	147-152	serpin family A member 4	Homo sapiens	95-98