PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
28673807-0	2017	Walsuronoid B induces mitochondrial and lysosomal dysfunction leading to apoptotic rather than autophagic cell death via ROS/p53 signaling pathways in liver cancer.	walsuronoid B	0-13	tumor protein p53	Homo sapiens	125-128
28673807-5	2017	Walsuronoid B induced cell death through G2/M phase arrest and apoptosis and induced the accumulation of autophagosomes through the suppression of mTOR signaling, which serves as a cell survival mechanism and prevents cell death.	walsuronoid B	0-13	mechanistic target of rapamycin kinase	Homo sapiens	147-151
28673807-8	2017	In addition, ROS induced by walsuronoid B upregulated p53 levels; conversely, p53 stimulated ROS.	walsuronoid B	28-41	tumor protein p53	Homo sapiens	54-57
28673807-12	2017	In summary, our findings demonstrated that walsuronoid B caused G2/M phase arrest and induced mitochondrial and lysosomal apoptosis through the ROS/p53 signaling pathway in human liver cancer cells in vitro and in vivo.	walsuronoid B	43-56	tumor protein p53	Homo sapiens	148-151