PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
18779575-4	2008	Defects in MMACHC represent the most common cause of inborn errors of B(12) metabolism, and our results explain the observation that fibroblasts from these patients are poorly responsive to vitamin B(12) but show some metabolic correction with aquocobalamin, a cofactor form lacking the cyanide ligand, which is mirrored by patients showing poorer clinical responsiveness to cyano- versus aquocobalamin.	aquacobalamin	244-257	metabolism of cobalamin associated C	Homo sapiens	11-17
1552368-3	1992	By mixing the purified cytochrome b5 with cytochrome b5 reductase, cob(II)alamin was immediately formed from aquacobalamin and NADH.	aquacobalamin	109-122	cytochrome b5 type A	Rattus norvegicus	42-55
3338997-2	1988	A vitamin B12-binding protein (haptocorrin) from chicken serum has been purified to homogeneity by photodissociative affinity chromatography and characterized by gel electrophoresis and UV-visible spectrophotometry of its aquocobalamin, hydroxocobalamin, and cyanocobalamin complexes.	aquacobalamin	222-235	transcobalamin 1	Homo sapiens	31-42
5529636-0	1970	Binding of aquocobalamin to the histidine residues in bovine serum albumin.	aquacobalamin	11-24	albumin	Homo sapiens	61-74
31773269-3	2020	This interaction leads to the formation of one-electron reduced cobalamin, cob(II)alamin, and proceeds via water substitution on aquacobalamin by NADH and further decomposition of NADH-Co(III) complex to cob(II)alamin and NADH +.	aquacobalamin	129-142	metabolism of cobalamin associated B	Homo sapiens	64-67
31773269-3	2020	This interaction leads to the formation of one-electron reduced cobalamin, cob(II)alamin, and proceeds via water substitution on aquacobalamin by NADH and further decomposition of NADH-Co(III) complex to cob(II)alamin and NADH +.	aquacobalamin	129-142	metabolism of cobalamin associated B	Homo sapiens	75-78
31773269-4	2020	Riboflavin catalyzes the reduction of aquacobalamin by NADH both in free form and with aquacobalamin bound to the cobalamin processing enzyme CblC.	aquacobalamin	38-51	Cbl proto-oncogene C	Homo sapiens	142-146
27864634-1	2017	Reactions of aquacobalamin (H2O-Cbl(III)) and its one-electron reduced form (cob(II)alamin, Cbl(II)) with chlorite (ClO2-) and chlorine dioxide (ClO 2  ) were studied by conventional and stopped-flow UV-Vis spectroscopies and matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS).	aquacobalamin	13-26	Cbl proto-oncogene	Homo sapiens	32-35
27864634-1	2017	Reactions of aquacobalamin (H2O-Cbl(III)) and its one-electron reduced form (cob(II)alamin, Cbl(II)) with chlorite (ClO2-) and chlorine dioxide (ClO 2  ) were studied by conventional and stopped-flow UV-Vis spectroscopies and matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS).	aquacobalamin	13-26	Cbl proto-oncogene	Homo sapiens	92-95
25994134-5	2015	All acyl-Cbls underwent the Co-C bond cleavage upon photo-irradiation with a tungsten light bulb as well as upon treatment with alkali, forming aquacobalamin (aqCbl) and hydroxocobalamin (OH-Cbl), respectively, under air.	aquacobalamin	144-157	Cbl proto-oncogene	Homo sapiens	9-12
25994134-5	2015	All acyl-Cbls underwent the Co-C bond cleavage upon photo-irradiation with a tungsten light bulb as well as upon treatment with alkali, forming aquacobalamin (aqCbl) and hydroxocobalamin (OH-Cbl), respectively, under air.	aquacobalamin	159-164	Cbl proto-oncogene	Homo sapiens	9-12
25994134-6	2015	Formyl-Cbl was thermally unstable and decomposed to aqCbl, and the thermal stability in neutral solution was much lower than in diluted HCl.	aquacobalamin	52-57	Cbl proto-oncogene	Homo sapiens	7-10
8229302-6	1993	The enzyme was specific for NADPH as electron donor and had the ability to reduce cytochrome c (15.4 mumol.min-1 x mg protein-1), potassium ferricyanide (4.9 mumol.min-1 x mg protein-1) and 2,6-dichlorophenolindophenol (16.8 mumol.min-1.mg protein-1) as well as aquacobalamin (6.4 mumol.min-1 x mg protein-1).	aquacobalamin	262-275	cytochrome c, somatic	Homo sapiens	82-94
1552368-3	1992	By mixing the purified cytochrome b5 with cytochrome b5 reductase, cob(II)alamin was immediately formed from aquacobalamin and NADH.	aquacobalamin	109-122	cytochrome b5 type A	Rattus norvegicus	23-36
2559772-1	1989	Corrinoids, such as aquocobalamin, methylcobalamin, and (cyanoaquo)cobinamide, catalyze the reductive dehalogenation of CCl4 with titanium(III) citrate as the electron donor [Krone et al.	aquacobalamin	20-33	C-C motif chemokine ligand 4	Homo sapiens	120-124
24742678-4	2014	In this study, we discovered two new GSH-dependent activities associated with the Caenorhabditis elegans CblC for generating cob(II)alamin: decyanation of CNCbl and reduction of aquocobalamin (OH2Cbl).	aquacobalamin	178-191	Cbl proto-oncogene C	Homo sapiens	105-109
11788601-1	2002	Changes in the absorbance spectrum of aquo-cobalamin (Cbl x OH(2)) revealed that its binding to transcobalamin (TC) is followed by slow conformational reorganization of the protein-ligand complex (Fedosov, S. N., Fedosova, N. U., Nexo, E., and Petersen, T. E. (2000) J. Biol.	aquacobalamin	38-52	Cbl proto-oncogene	Homo sapiens	54-57
16417369-1	2006	Femtosecond transient IR and visible absorption spectroscopies have been employed to investigate the excited-state photophysics of vitamin B12 (cyanocobalamin, CNCbl) and the related cob(III)alamins, azidocobalamin (N3Cbl), and aquocobalamin (H2OCbl).	aquacobalamin	228-241	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	139-142
15726141-0	2005	Probing the nature of the Co(III) ion in cobalamins: a comparison of the reaction of aquacobalamin (vitamin B12a) and aqua-10-chlorocobalamin with some anionic and N-donor ligands.	aquacobalamin	85-98	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	26-33
15726141-0	2005	Probing the nature of the Co(III) ion in cobalamins: a comparison of the reaction of aquacobalamin (vitamin B12a) and aqua-10-chlorocobalamin with some anionic and N-donor ligands.	aquacobalamin	100-112	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	26-33
16441149-1	2006	The reactions of aquacobalamin (Cbl(III)H2O, vitamin B12a) and reduced cobalamin (Cbl(II), vitamin B12r) with the nitrosothiols S-nitrosoglutathione (GSNO) and S-nitroso-N-acetylpenicillamine (SNAP) were studied in aqueous solution at pH 7.4.	aquacobalamin	17-30	Cbl proto-oncogene	Homo sapiens	32-35