PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 18779575-4 2008 Defects in MMACHC represent the most common cause of inborn errors of B(12) metabolism, and our results explain the observation that fibroblasts from these patients are poorly responsive to vitamin B(12) but show some metabolic correction with aquocobalamin, a cofactor form lacking the cyanide ligand, which is mirrored by patients showing poorer clinical responsiveness to cyano- versus aquocobalamin. aquacobalamin 244-257 metabolism of cobalamin associated C Homo sapiens 11-17 16441149-1 2006 The reactions of aquacobalamin (Cbl(III)H2O, vitamin B12a) and reduced cobalamin (Cbl(II), vitamin B12r) with the nitrosothiols S-nitrosoglutathione (GSNO) and S-nitroso-N-acetylpenicillamine (SNAP) were studied in aqueous solution at pH 7.4. aquacobalamin 17-30 Cbl proto-oncogene Homo sapiens 32-35 15726141-0 2005 Probing the nature of the Co(III) ion in cobalamins: a comparison of the reaction of aquacobalamin (vitamin B12a) and aqua-10-chlorocobalamin with some anionic and N-donor ligands. aquacobalamin 85-98 mitochondrially encoded cytochrome c oxidase III Homo sapiens 26-33 16417369-1 2006 Femtosecond transient IR and visible absorption spectroscopies have been employed to investigate the excited-state photophysics of vitamin B12 (cyanocobalamin, CNCbl) and the related cob(III)alamins, azidocobalamin (N3Cbl), and aquocobalamin (H2OCbl). aquacobalamin 228-241 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 139-142 15726141-0 2005 Probing the nature of the Co(III) ion in cobalamins: a comparison of the reaction of aquacobalamin (vitamin B12a) and aqua-10-chlorocobalamin with some anionic and N-donor ligands. aquacobalamin 100-112 mitochondrially encoded cytochrome c oxidase III Homo sapiens 26-33 11788601-1 2002 Changes in the absorbance spectrum of aquo-cobalamin (Cbl x OH(2)) revealed that its binding to transcobalamin (TC) is followed by slow conformational reorganization of the protein-ligand complex (Fedosov, S. N., Fedosova, N. U., Nexo, E., and Petersen, T. E. (2000) J. Biol. aquacobalamin 38-52 Cbl proto-oncogene Homo sapiens 54-57 8229302-6 1993 The enzyme was specific for NADPH as electron donor and had the ability to reduce cytochrome c (15.4 mumol.min-1 x mg protein-1), potassium ferricyanide (4.9 mumol.min-1 x mg protein-1) and 2,6-dichlorophenolindophenol (16.8 mumol.min-1.mg protein-1) as well as aquacobalamin (6.4 mumol.min-1 x mg protein-1). aquacobalamin 262-275 cytochrome c, somatic Homo sapiens 82-94 1552368-3 1992 By mixing the purified cytochrome b5 with cytochrome b5 reductase, cob(II)alamin was immediately formed from aquacobalamin and NADH. aquacobalamin 109-122 cytochrome b5 type A Rattus norvegicus 42-55 1552368-3 1992 By mixing the purified cytochrome b5 with cytochrome b5 reductase, cob(II)alamin was immediately formed from aquacobalamin and NADH. aquacobalamin 109-122 cytochrome b5 type A Rattus norvegicus 23-36 27864634-1 2017 Reactions of aquacobalamin (H2O-Cbl(III)) and its one-electron reduced form (cob(II)alamin, Cbl(II)) with chlorite (ClO2-) and chlorine dioxide (ClO 2 ) were studied by conventional and stopped-flow UV-Vis spectroscopies and matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS). aquacobalamin 13-26 Cbl proto-oncogene Homo sapiens 32-35 2559772-1 1989 Corrinoids, such as aquocobalamin, methylcobalamin, and (cyanoaquo)cobinamide, catalyze the reductive dehalogenation of CCl4 with titanium(III) citrate as the electron donor [Krone et al. aquacobalamin 20-33 C-C motif chemokine ligand 4 Homo sapiens 120-124 3338997-2 1988 A vitamin B12-binding protein (haptocorrin) from chicken serum has been purified to homogeneity by photodissociative affinity chromatography and characterized by gel electrophoresis and UV-visible spectrophotometry of its aquocobalamin, hydroxocobalamin, and cyanocobalamin complexes. aquacobalamin 222-235 transcobalamin 1 Homo sapiens 31-42 5529636-0 1970 Binding of aquocobalamin to the histidine residues in bovine serum albumin. aquacobalamin 11-24 albumin Homo sapiens 61-74 31773269-3 2020 This interaction leads to the formation of one-electron reduced cobalamin, cob(II)alamin, and proceeds via water substitution on aquacobalamin by NADH and further decomposition of NADH-Co(III) complex to cob(II)alamin and NADH +. aquacobalamin 129-142 metabolism of cobalamin associated B Homo sapiens 64-67 31773269-3 2020 This interaction leads to the formation of one-electron reduced cobalamin, cob(II)alamin, and proceeds via water substitution on aquacobalamin by NADH and further decomposition of NADH-Co(III) complex to cob(II)alamin and NADH +. aquacobalamin 129-142 metabolism of cobalamin associated B Homo sapiens 75-78 31773269-4 2020 Riboflavin catalyzes the reduction of aquacobalamin by NADH both in free form and with aquacobalamin bound to the cobalamin processing enzyme CblC. aquacobalamin 38-51 Cbl proto-oncogene C Homo sapiens 142-146 27864634-1 2017 Reactions of aquacobalamin (H2O-Cbl(III)) and its one-electron reduced form (cob(II)alamin, Cbl(II)) with chlorite (ClO2-) and chlorine dioxide (ClO 2 ) were studied by conventional and stopped-flow UV-Vis spectroscopies and matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS). aquacobalamin 13-26 Cbl proto-oncogene Homo sapiens 92-95 25994134-5 2015 All acyl-Cbls underwent the Co-C bond cleavage upon photo-irradiation with a tungsten light bulb as well as upon treatment with alkali, forming aquacobalamin (aqCbl) and hydroxocobalamin (OH-Cbl), respectively, under air. aquacobalamin 144-157 Cbl proto-oncogene Homo sapiens 9-12 25994134-5 2015 All acyl-Cbls underwent the Co-C bond cleavage upon photo-irradiation with a tungsten light bulb as well as upon treatment with alkali, forming aquacobalamin (aqCbl) and hydroxocobalamin (OH-Cbl), respectively, under air. aquacobalamin 159-164 Cbl proto-oncogene Homo sapiens 9-12 25994134-6 2015 Formyl-Cbl was thermally unstable and decomposed to aqCbl, and the thermal stability in neutral solution was much lower than in diluted HCl. aquacobalamin 52-57 Cbl proto-oncogene Homo sapiens 7-10 24742678-4 2014 In this study, we discovered two new GSH-dependent activities associated with the Caenorhabditis elegans CblC for generating cob(II)alamin: decyanation of CNCbl and reduction of aquocobalamin (OH2Cbl). aquacobalamin 178-191 Cbl proto-oncogene C Homo sapiens 105-109