PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 7510340-2 1994 Synthesis of 2,2"-dithiobis(1H-indole-3-alkanamides) and investigation of their inhibitory activity against epidermal growth factor receptor and pp60v-src protein tyrosine kinases. 2,2"-dithiobis 13-27 epidermal growth factor receptor Homo sapiens 108-140 8355247-2 1993 Structure-activity relationships for inhibition of epidermal growth factor receptor tyrosine kinase activity by 2,3-dihydro-2-thioxo-1H-indole-3-alkanoic acids and 2,2"-dithiobis(1H-indole-3-alkanoic acids). 2,2"-dithiobis 164-178 epidermal growth factor receptor Mus musculus 51-83 6662893-3 1983 p-Sulfamoylbenzaldehyde and benzaldehyde formed enzymatically from p-sulfamoylbenzylamine (the substrate of monoamine oxidase A) and benzylamine (the substrate of monoamine oxidase B), respectively, are converted simultaneously into fluorescent compounds with 2,2"-dithiobis(1-aminonaphthalene). 2,2"-dithiobis 260-274 monoamine oxidase A Rattus norvegicus 108-127 2898532-4 1988 Although analysis of cis-1 with 2,2"-dithiobis(5-nitrobenzoic acid) revealed significant loss of the free thiol group under enzymatic assay conditions, the addition of the reducing agent, dithiothreitol, to the enzymatic reaction mixtures afforded cis-1 complete protection against this chemical decomposition, as evidenced by lowering of the inhibition constant in the presence of dithiothreitol. 2,2"-dithiobis 32-46 suppressor of cytokine signaling 1 Homo sapiens 21-26 6662893-3 1983 p-Sulfamoylbenzaldehyde and benzaldehyde formed enzymatically from p-sulfamoylbenzylamine (the substrate of monoamine oxidase A) and benzylamine (the substrate of monoamine oxidase B), respectively, are converted simultaneously into fluorescent compounds with 2,2"-dithiobis(1-aminonaphthalene). 2,2"-dithiobis 260-274 monoamine oxidase B Rattus norvegicus 163-182 22381367-6 2012 A major product of RVX degradation, 2,2"-dithiobis(N,N-diethylethanamine), caused significant inhibition of AChE at concentrations of >=0.1 mM (P<0.01) and had a false positive effect at higher concentrations (>=2 mM). 2,2"-dithiobis 36-50 acetylcholinesterase (Cartwright blood group) Homo sapiens 108-112