PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
21889459-1	2011	The orientation behavior of Bombolitin II (BLT2) in the dipalmitoylphosphatidylcholine membrane bilayer was investigated by using molecular-dynamics simulation.	1,2-Dipalmitoylphosphatidylcholine	56-86	leukotriene B4 receptor 2	Homo sapiens	43-47
21621398-8	2011	However, after the enzyme action the products of DPPC hydrolysis by PLA(2) (palmitic acid and lysophosphatidylcholine) increased again the hydrophilic character of Al(2)O(3) surface (a minor increase in gamma(s)(AB) component and drastic increase of the electron-donor gamma(s)(-) parameter was noticeable).	1,2-Dipalmitoylphosphatidylcholine	49-53	phospholipase A2 group IIA	Homo sapiens	68-73
21621398-9	2011	After treatment with DPPC or DPPC+enzyme PLA(2) solution the changes of the total surface free energy of alumina and its Lifshits-van der Waals (gamma(s)(LW)) component were in the range 7-10 mJ/m(2), but the most considerable and delivering more interesting information were the changes of the electron-donor (gamma(s)(-)) parameter ranging from 27 to 35 mJ/m(2).	1,2-Dipalmitoylphosphatidylcholine	29-33	phospholipase A2 group IIA	Homo sapiens	41-46
21640149-3	2011	We hypothesized that Brij surfactants resembling the chemical structures of MSPC and DSPE-PEG(2000) could be utilized for generating a thermosensitive formulation with DPPC.	1,2-Dipalmitoylphosphatidylcholine	168-172	progestagen associated endometrial protein	Homo sapiens	90-93
22047207-2	2011	We demonstrate that the dispersal of as-prepared (AP), purified (PD), and carboxylated (COOH) MWCNTs by bovine serum albumin (BSA) and dipalmitoylphosphatidylcholine (DPPC) influences TGF-beta1, PDGF-AA, and IL-1beta production in vitro and in vivo.	1,2-Dipalmitoylphosphatidylcholine	135-165	transforming growth factor beta 1	Homo sapiens	184-193
21767528-4	2011	In binary mixtures of DPPC with lung surfactant peptide fragment SP-B(1-25), the ordered side of the hysteresis loop is abolished altogether, suggesting that SP-B(1-25) effectively nucleates disorder in the monolayer on heating.	1,2-Dipalmitoylphosphatidylcholine	22-26	surfactant protein B	Homo sapiens	65-69
21767528-4	2011	In binary mixtures of DPPC with lung surfactant peptide fragment SP-B(1-25), the ordered side of the hysteresis loop is abolished altogether, suggesting that SP-B(1-25) effectively nucleates disorder in the monolayer on heating.	1,2-Dipalmitoylphosphatidylcholine	22-26	surfactant protein B	Homo sapiens	158-162
21621398-0	2011	Changes in wetting properties of alumina surface treated with DPPC in the presence of phospholipase A2 enzyme.	1,2-Dipalmitoylphosphatidylcholine	62-66	phospholipase A2 group IB	Homo sapiens	86-102
20048161-3	2010	TNAP reconstitution proved virtually complete in DPPC liposomes.	1,2-Dipalmitoylphosphatidylcholine	49-53	alkaline phosphatase, liver/bone/kidney	Mus musculus	0-4
21315062-0	2011	Interactions of the AT1 antagonist valsartan with dipalmitoyl-phosphatidylcholine bilayers.	1,2-Dipalmitoylphosphatidylcholine	50-81	angiotensin II receptor type 1	Homo sapiens	20-23
21702369-0	2011	Chemical stability and cytotoxicity of human insulin loaded in cationic DPPC/CTA/DDAB liposomes.	1,2-Dipalmitoylphosphatidylcholine	72-76	insulin	Homo sapiens	45-52
21702369-6	2011	The synthesized cationic lipid, CTA, and the DPPC/Chol/CTA liposomes loaded with human insulin demonstrated no cytotoxicity on normal human skin fibroblast but some cytotoxic effects on mouth epidermal cancer cell line.	1,2-Dipalmitoylphosphatidylcholine	45-49	insulin	Homo sapiens	87-94
21702369-7	2011	This study has demonstrated the enhancement of chemical stability of human insulin with no cytotoxicity when loaded this protein in cationic DPPC/CTA/DDAB liposomes.	1,2-Dipalmitoylphosphatidylcholine	141-145	insulin	Homo sapiens	75-82
21068446-1	2011	Acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1) is a relatively newly described and yet indispensable enzyme needed for generation of the bioactive surfactant phospholipid, dipalmitoylphosphatidylcholine (DPPtdCho).	1,2-Dipalmitoylphosphatidylcholine	185-215	lysophosphatidylcholine acyltransferase 1	Homo sapiens	0-50
21068446-1	2011	Acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1) is a relatively newly described and yet indispensable enzyme needed for generation of the bioactive surfactant phospholipid, dipalmitoylphosphatidylcholine (DPPtdCho).	1,2-Dipalmitoylphosphatidylcholine	185-215	lysophosphatidylcholine acyltransferase 1	Homo sapiens	52-58
21068446-1	2011	Acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1) is a relatively newly described and yet indispensable enzyme needed for generation of the bioactive surfactant phospholipid, dipalmitoylphosphatidylcholine (DPPtdCho).	1,2-Dipalmitoylphosphatidylcholine	217-225	lysophosphatidylcholine acyltransferase 1	Homo sapiens	0-50
21068446-1	2011	Acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1) is a relatively newly described and yet indispensable enzyme needed for generation of the bioactive surfactant phospholipid, dipalmitoylphosphatidylcholine (DPPtdCho).	1,2-Dipalmitoylphosphatidylcholine	217-225	lysophosphatidylcholine acyltransferase 1	Homo sapiens	52-58
21068446-7	2011	LPCAT1 is the first lipogenic substrate for beta-TrCP, and the results suggest that modulation of the GSK-3beta-SCFbeta(TrCP) E3 ligase effector pathway might be a unique strategy to optimize dipalmitoylphosphatidylcholine levels in sepsis.	1,2-Dipalmitoylphosphatidylcholine	192-222	lysophosphatidylcholine acyltransferase 1	Homo sapiens	0-6
20959114-0	2011	Kinetics of degradation of dipalmitoylphosphatidylcholine (DPPC) bilayers as a result of vipoxin phospholipase A2 activity: an atomic force microscopy (AFM) approach.	1,2-Dipalmitoylphosphatidylcholine	27-57	phospholipase A2 group IB	Homo sapiens	97-113
20959114-0	2011	Kinetics of degradation of dipalmitoylphosphatidylcholine (DPPC) bilayers as a result of vipoxin phospholipase A2 activity: an atomic force microscopy (AFM) approach.	1,2-Dipalmitoylphosphatidylcholine	59-63	phospholipase A2 group IB	Homo sapiens	97-113
20829000-1	2010	Adsorption of fibrinogen to the monolayers of mixed lipids, dipalmitoyl phosphatidyl choline (DPPC) and eicosylamine (EA) was measured at a surface pressure of 20 mN/m by an in situ surface plasmon resonance technique.	1,2-Dipalmitoylphosphatidylcholine	60-92	fibrinogen beta chain	Homo sapiens	14-24
20829000-1	2010	Adsorption of fibrinogen to the monolayers of mixed lipids, dipalmitoyl phosphatidyl choline (DPPC) and eicosylamine (EA) was measured at a surface pressure of 20 mN/m by an in situ surface plasmon resonance technique.	1,2-Dipalmitoylphosphatidylcholine	94-98	fibrinogen beta chain	Homo sapiens	14-24
20829000-5	2010	At a higher protein concentration (0.06 mg/ml) both the fibrinogen adsorbed amount and its maximum adsorption rate showed excess values relative to the pure EA for 1:1, 2:1 and 3:1 DPPC+EA monolayers.	1,2-Dipalmitoylphosphatidylcholine	181-185	fibrinogen beta chain	Homo sapiens	56-66
20858421-10	2010	The ability of SP-B(1-25) to fuse lipid lamellae via this mechanism, particularly those enriched in DPPC, suggests a specific role for the highly conserved N-terminus of SP-B in the packing of lipid lamellae into surfactant lamellar bodies or in stabilizing multilayer structures at the air-liquid interface.	1,2-Dipalmitoylphosphatidylcholine	100-104	surfactant protein B	Homo sapiens	15-19
20435014-8	2010	In contrast, the addition of PA has a charge-dependent condensing affect on DPPC monolayers containing SP-C.	1,2-Dipalmitoylphosphatidylcholine	76-80	surfactant protein C	Homo sapiens	103-107
20599851-1	2010	We analyzed the kinetics for the subgel (SGI) phase formation in DPPC/DOPC binary bilayers paying attention to DOPC-induced modification of the bilayer physical properties.	1,2-Dipalmitoylphosphatidylcholine	65-69	semenogelin 1	Homo sapiens	41-44
20599851-2	2010	Differential scanning calorimetry and X-ray diffraction revealed that addition of DOPC reduced the apparent initial lag time to start the SGI phase formation, and that the SGI phase in the binary bilayers had basically the same structure as that in pure DPPC bilayers though addition of DOPC markedly increased the peak temperature and enthalpy of the subtransition in heating.	1,2-Dipalmitoylphosphatidylcholine	254-258	semenogelin 1	Homo sapiens	172-175
20599851-3	2010	Moreover, addition of DOPC abolished the prolongation of the initial lag time in pure DPPC bilayers induced by lowering the incubation temperature from 0 to -5 degrees C. Our results suggested that DOPC molecules work as a diffusion enhancer to promote the nucleation of the SGI phase, and relatively destabilize the gel phase so that the formed SGI phase transforms into the ripple phase in heating.	1,2-Dipalmitoylphosphatidylcholine	86-90	semenogelin 1	Homo sapiens	275-278
20599851-3	2010	Moreover, addition of DOPC abolished the prolongation of the initial lag time in pure DPPC bilayers induced by lowering the incubation temperature from 0 to -5 degrees C. Our results suggested that DOPC molecules work as a diffusion enhancer to promote the nucleation of the SGI phase, and relatively destabilize the gel phase so that the formed SGI phase transforms into the ripple phase in heating.	1,2-Dipalmitoylphosphatidylcholine	86-90	semenogelin 1	Homo sapiens	346-349
21105403-0	2010	[Raman spectroscopy study on the interaction of ginsenoside Rb1 with DPPC bilayers].	1,2-Dipalmitoylphosphatidylcholine	69-73	RB transcriptional corepressor 1	Homo sapiens	60-63
21105403-6	2010	Both of them increased with adding the concentration of Rb1 to DPPC bilayers.	1,2-Dipalmitoylphosphatidylcholine	63-67	RB transcriptional corepressor 1	Homo sapiens	56-59
21105403-13	2010	Compared with those results, the action mode of ginsenoside Rb1 on DPPC bilayers may be because of hydrogen bonds that can be easily formed for the sugar moieties and the hydroxyls in Rb1 molecule.	1,2-Dipalmitoylphosphatidylcholine	67-71	RB transcriptional corepressor 1	Homo sapiens	60-63
21105403-13	2010	Compared with those results, the action mode of ginsenoside Rb1 on DPPC bilayers may be because of hydrogen bonds that can be easily formed for the sugar moieties and the hydroxyls in Rb1 molecule.	1,2-Dipalmitoylphosphatidylcholine	67-71	RB transcriptional corepressor 1	Homo sapiens	184-187
20222694-5	2010	The results also showed that colipase and lipase adsorbed exclusively onto the mixed DPPC-bile salt regions and not the DPPC condensed phase.	1,2-Dipalmitoylphosphatidylcholine	85-89	colipase	Homo sapiens	29-37
20222694-6	2010	When the colipase and lipase were in excess, they fully covered the mixed DPPC-bile salt regions.	1,2-Dipalmitoylphosphatidylcholine	74-78	colipase	Homo sapiens	9-28
20222694-11	2010	Thus, there are fewer hydrophobic patches that are of sufficient size to accommodate the colipase on the mixed DGDG-bile salt monolayer compared to the mixed DPPC-bile salt regions.	1,2-Dipalmitoylphosphatidylcholine	158-162	colipase	Homo sapiens	89-97
20423923-8	2010	By contrast, SP-A shows features consistent with its preference for lipid ligands, including lipid A and the major surfactant lipid, dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	133-163	surfactant protein A1	Homo sapiens	13-17
20441751-1	2010	We monitored the action of phospholipase A(2) (PLA(2)) on L- and D-dipalmitoyl-phosphatidylcholine (DPPC) Langmuir monolayers by mounting a Langmuir-trough on a wide-field fluorescence microscope with single molecule sensitivity.	1,2-Dipalmitoylphosphatidylcholine	100-104	phospholipase A2 group IB	Homo sapiens	27-45
20441751-1	2010	We monitored the action of phospholipase A(2) (PLA(2)) on L- and D-dipalmitoyl-phosphatidylcholine (DPPC) Langmuir monolayers by mounting a Langmuir-trough on a wide-field fluorescence microscope with single molecule sensitivity.	1,2-Dipalmitoylphosphatidylcholine	100-104	phospholipase A2 group IB	Homo sapiens	47-53
20441751-4	2010	Domains of gel state L-DPPC were degraded exclusively from the gel-fluid interface where the buildup of negatively charged hydrolysis products, fatty acid salts, led to changes in the mobility of PLA(2).	1,2-Dipalmitoylphosphatidylcholine	21-27	phospholipase A2 group IB	Homo sapiens	196-202
19505544-6	2010	Affinity capillary electrophoresis (ACE) revealed an interaction between ghrelin and the negatively charged (DPPC:DPPS) liposomes, whereas only very small affinities were discerned in the other liposomal formulations of ghrelin.	1,2-Dipalmitoylphosphatidylcholine	109-113	ghrelin and obestatin prepropeptide	Rattus norvegicus	73-80
20188129-2	2010	The SOD-like activity is dependent on the stability of the ligand-metal complex on the liposome membrane, with the value being higher for the DPPC liposome and at a higher pH.	1,2-Dipalmitoylphosphatidylcholine	142-146	superoxide dismutase 1	Homo sapiens	4-7
21718059-11	2011	Moreover, matching SANS experiments showed that BmimBF(4) molecules prefer to be located inside the DPPC membrane rather than in water.	1,2-Dipalmitoylphosphatidylcholine	100-104	USH1 protein network component sans	Homo sapiens	19-23
21555131-4	2011	Due to the molecular level interaction, specifically at mole fraction 0.3, the isotherm obtained from that mixture resembled the isotherm obtained from the DPPC monolayer in the presence of SP-C.	1,2-Dipalmitoylphosphatidylcholine	156-160	surfactant protein C	Homo sapiens	190-194
20875392-5	2011	We found that if ceramide is in a tightly packed environment such as in sphingomyelin or dipalmitoylphosphatidylcholine containing membranes, the CERT transfer activity is markedly reduced.	1,2-Dipalmitoylphosphatidylcholine	89-119	ceramide transporter 1	Homo sapiens	146-150
20461428-2	2010	The effect of the surrounding environment (DPPC molecules) has been observed during the stretching or compressing of the L(24).	1,2-Dipalmitoylphosphatidylcholine	43-47	immunoglobulin kappa variable 1D-8	Homo sapiens	121-126
20713727-8	2010	LPCAT1 (also called AYTL2) is a phospholipid biosynthesis/remodeling enzyme that facilitates the conversion of palmitoyl-lysophosphatidylcholine to dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	148-178	lysophosphatidylcholine acyltransferase 1	Mus musculus	0-6
20713727-8	2010	LPCAT1 (also called AYTL2) is a phospholipid biosynthesis/remodeling enzyme that facilitates the conversion of palmitoyl-lysophosphatidylcholine to dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	148-178	lysophosphatidylcholine acyltransferase 1	Mus musculus	20-25
20713727-8	2010	LPCAT1 (also called AYTL2) is a phospholipid biosynthesis/remodeling enzyme that facilitates the conversion of palmitoyl-lysophosphatidylcholine to dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	180-184	lysophosphatidylcholine acyltransferase 1	Mus musculus	0-6
20713727-8	2010	LPCAT1 (also called AYTL2) is a phospholipid biosynthesis/remodeling enzyme that facilitates the conversion of palmitoyl-lysophosphatidylcholine to dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	180-184	lysophosphatidylcholine acyltransferase 1	Mus musculus	20-25
20713727-9	2010	The analysis of retinal lipids from rd11 and B6-JR2845 mice showed substantially reduced DPPC levels compared with C57BL/6J control mice, suggesting a causal link to photoreceptor dysfunction.	1,2-Dipalmitoylphosphatidylcholine	89-93	lysophosphatidylcholine acyltransferase 1	Mus musculus	36-40
20000434-4	2010	The enzyme PLA(2) hydrolyzes DPPC monolayers in the presence of a supersaturated calcium oxalate subphase, inducing the rapid and plentiful nucleation of calcium oxalate at the lipid interface.	1,2-Dipalmitoylphosphatidylcholine	29-33	phospholipase A2 group IB	Homo sapiens	11-17
20079684-6	2010	The kinetics of CPD transfer by recombinant cholesteryl ester transfer protein (CETP) to human plasma LDL is well described by two-exponential decay, the fast component with a shorter transfer time being more populated in PLPC compared to DPPC complexes.	1,2-Dipalmitoylphosphatidylcholine	239-243	cholesteryl ester transfer protein	Homo sapiens	44-78
20079684-6	2010	The kinetics of CPD transfer by recombinant cholesteryl ester transfer protein (CETP) to human plasma LDL is well described by two-exponential decay, the fast component with a shorter transfer time being more populated in PLPC compared to DPPC complexes.	1,2-Dipalmitoylphosphatidylcholine	239-243	cholesteryl ester transfer protein	Homo sapiens	80-84
20127783-8	2010	They give rise to hydron transfers, under the influence of the DPPC electric charges, evidenced by two broad FTIR absorptions above (BB1) and below (BB2) the nu(C-O) stretch.	1,2-Dipalmitoylphosphatidylcholine	63-67	neuromedin B receptor	Homo sapiens	133-136
20127783-8	2010	They give rise to hydron transfers, under the influence of the DPPC electric charges, evidenced by two broad FTIR absorptions above (BB1) and below (BB2) the nu(C-O) stretch.	1,2-Dipalmitoylphosphatidylcholine	63-67	gastrin releasing peptide receptor	Homo sapiens	149-152
20127783-9	2010	These hydron transfers occur along strong (D(+))H(+) bonds of pyridinium ions with pyridine (BB1) and DPPC C=O groups (BB2).	1,2-Dipalmitoylphosphatidylcholine	102-106	gastrin releasing peptide receptor	Homo sapiens	119-122
20129098-0	2010	Abeta/Cu-catalyzed oxidation of cholesterol in 1,2-dipalmitoyl phosphatidylcholine liposome membrane.	1,2-Dipalmitoylphosphatidylcholine	47-82	amyloid beta precursor protein	Homo sapiens	0-5
19648651-3	2010	This study investigates the effect of the lipid-rich surfactant preparations Survanta, Curosurf, and the major surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC) on interleukin-8 (IL-8) gene and protein expression in human A549 lung epithelial cells using immunoassay and PCR techniques.	1,2-Dipalmitoylphosphatidylcholine	167-171	C-X-C motif chemokine ligand 8	Homo sapiens	176-189
19648651-5	2010	The lipid-rich surfactant preparations Survanta, Curosurf, and DPPC, at physiological concentrations, significantly downregulated lipopolysaccharide (LPS)-induced IL-8 expression in A549 cells both at the mRNA and protein levels.	1,2-Dipalmitoylphosphatidylcholine	63-67	C-X-C motif chemokine ligand 8	Homo sapiens	163-167
19384981-5	2009	The closely related Fra-1 and c-Fos share affinity for anionic lipids but the former has more affinity for a condensed phase and senses a change in DPPC phase, while the latter has more affinity for an expanded phase.	1,2-Dipalmitoylphosphatidylcholine	148-152	FOS like 1, AP-1 transcription factor subunit	Homo sapiens	20-25
19577642-6	2009	Acidic Ca(2+)-independent PLA2 (aiPLA2), of lysosomal origin, has additionally antioxidant properties, (peroxiredoxin VI activity), and participates in the formation of dipalmitoyl-phosphatidylcholine in lung surfactant.	1,2-Dipalmitoylphosphatidylcholine	169-200	phospholipase A2 group VI	Homo sapiens	26-30
19577642-6	2009	Acidic Ca(2+)-independent PLA2 (aiPLA2), of lysosomal origin, has additionally antioxidant properties, (peroxiredoxin VI activity), and participates in the formation of dipalmitoyl-phosphatidylcholine in lung surfactant.	1,2-Dipalmitoylphosphatidylcholine	169-200	peroxiredoxin 6	Homo sapiens	32-38
19917227-5	2009	SP-C modulates the effect of cholesterol to reduce the enthalpy associated with the gel-to-liquid-crystalline melting transition in dipalmitoylphosphatidylcholine (DPPC) bilayers, as analyzed by differential scanning calorimetry.	1,2-Dipalmitoylphosphatidylcholine	132-162	surfactant protein C	Homo sapiens	0-4
19917227-5	2009	SP-C modulates the effect of cholesterol to reduce the enthalpy associated with the gel-to-liquid-crystalline melting transition in dipalmitoylphosphatidylcholine (DPPC) bilayers, as analyzed by differential scanning calorimetry.	1,2-Dipalmitoylphosphatidylcholine	164-168	surfactant protein C	Homo sapiens	0-4
19917227-7	2009	Incorporation of 1% or 2% SP-C (protein/phospholipid by weight) promotes almost instantaneous adsorption of suspensions of DPPC/palmitoyloleoylphospatidylcholine (POPC)/palmitoyloleoyl-phosphatidylglycerol (POPG) (50:25:15, w/w/w) into the air-liquid interface of a captive bubble, in both the absence and presence of cholesterol.	1,2-Dipalmitoylphosphatidylcholine	123-127	surfactant protein C	Homo sapiens	26-30
19384981-5	2009	The closely related Fra-1 and c-Fos share affinity for anionic lipids but the former has more affinity for a condensed phase and senses a change in DPPC phase, while the latter has more affinity for an expanded phase.	1,2-Dipalmitoylphosphatidylcholine	148-152	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	30-35
19490108-5	2009	In the present study, we present an extensive analysis of lipid parameters for a model dipalmitoylphosphatidylcholine bilayer in the presence of the 40-residue Abeta peptide (Abeta40).	1,2-Dipalmitoylphosphatidylcholine	87-117	amyloid beta precursor protein	Homo sapiens	160-165
19362071-1	2009	In this present work we have studied the effect of MARCKS (151-175) peptide on a mixed DPPC/PIP2 monolayer.	1,2-Dipalmitoylphosphatidylcholine	87-91	myristoylated alanine rich protein kinase C substrate	Homo sapiens	51-57
19224204-0	2009	Perturbation of DPPC/POPG bilayers by the N-terminal helix of lung surfactant protein SP-B: a (2)H NMR study.	1,2-Dipalmitoylphosphatidylcholine	16-20	surfactant protein B	Rattus norvegicus	86-90
19167476-4	2009	To evaluate the in vivo capability of 1-MTX to radiosensitize tumors, we developed temperature-sensitive liposomal 1-MTX using DPPC:DMPC:DSPC (4:1:1 molar ratio) with intention of overcoming lethal toxicity of 1-MTX and controlling drug-release.	1,2-Dipalmitoylphosphatidylcholine	127-131	metaxin 1	Homo sapiens	117-120
19588235-3	2009	The fractionation (Sephadex G-200) of mixtures of the OA-complexes with the vesicles shows that OA-binding increases the affinity of alpha-LA to DPPC vesicles.	1,2-Dipalmitoylphosphatidylcholine	145-149	lactalbumin alpha	Homo sapiens	133-141
19167476-4	2009	To evaluate the in vivo capability of 1-MTX to radiosensitize tumors, we developed temperature-sensitive liposomal 1-MTX using DPPC:DMPC:DSPC (4:1:1 molar ratio) with intention of overcoming lethal toxicity of 1-MTX and controlling drug-release.	1,2-Dipalmitoylphosphatidylcholine	127-131	metaxin 1	Homo sapiens	117-120
19086158-4	2008	To investigate the binding of the Gla domain of prothrombin fragment 1 (PT1) to anionic lipids in the presence of Ca2+, we have conducted MD simulations of the protein with one and two dipalmitoylphosphatidylserines (DPPS) in a dipalmitoylphosphatidylcholine (DPPC) bilayer membrane.	1,2-Dipalmitoylphosphatidylcholine	228-258	coagulation factor II, thrombin	Homo sapiens	48-59
20298384-10	2009	CONCLUSION: Elevated DPPC levels are evident in induced sputum of all asthmatic children and they are significantly related to sputum ECP levels and pulmonary function test parameters.	1,2-Dipalmitoylphosphatidylcholine	21-25	ribonuclease A family member 3	Homo sapiens	134-137
19254533-4	2009	We applied Brownian dynamics simulations to investigate the effect of an atomistically modeled dipalmitoyl phosphatidylcholine membrane on the association behavior of cytochrome c toward COX from Paracoccus denitrificans.	1,2-Dipalmitoylphosphatidylcholine	95-126	cytochrome c, somatic	Equus caballus	167-179
19124026-5	2009	Data on the conformation, mobility, distance, and surface exposure of regions revealed by the cysteine probes were modeled into the molecular envelope of apoE bound to dipalmitoylphosphatidylcholine that had been determined by X-ray analysis.	1,2-Dipalmitoylphosphatidylcholine	168-198	apolipoprotein E	Homo sapiens	154-158
19186121-4	2009	We used unconstrained and umbrella sampling molecular dynamics simulations to investigate interactions between the 42-amino acid Abeta peptide and model bilayers of zwitterionic dipalmitoylphosphatidylcholine (DPPC) lipids and anionic dioleoylphosphatidylserine (DOPS) lipids.	1,2-Dipalmitoylphosphatidylcholine	178-208	amyloid beta precursor protein	Homo sapiens	129-134
19186121-4	2009	We used unconstrained and umbrella sampling molecular dynamics simulations to investigate interactions between the 42-amino acid Abeta peptide and model bilayers of zwitterionic dipalmitoylphosphatidylcholine (DPPC) lipids and anionic dioleoylphosphatidylserine (DOPS) lipids.	1,2-Dipalmitoylphosphatidylcholine	210-214	amyloid beta precursor protein	Homo sapiens	129-134
19186121-5	2009	Using these methods, we determined that Abeta is attracted to the surface of DPPC and DOPS bilayers over the small length scales used in these simulations.	1,2-Dipalmitoylphosphatidylcholine	77-81	amyloid beta precursor protein	Homo sapiens	40-45
18937360-3	2009	P-gp was reconstituted in egg-phosphatidylcholine (PhC) liposomes with or without cholesterol, 1,2-dipalmitoyl-phosphatidylcholine (DPPC), alpha-tocopherol (alpha-Toc) or 2,2,5,7,8-pentamethyl-6-chromanol (PMC).	1,2-Dipalmitoylphosphatidylcholine	95-130	ATP binding cassette subfamily B member 1	Homo sapiens	0-4
18937360-3	2009	P-gp was reconstituted in egg-phosphatidylcholine (PhC) liposomes with or without cholesterol, 1,2-dipalmitoyl-phosphatidylcholine (DPPC), alpha-tocopherol (alpha-Toc) or 2,2,5,7,8-pentamethyl-6-chromanol (PMC).	1,2-Dipalmitoylphosphatidylcholine	132-136	ATP binding cassette subfamily B member 1	Homo sapiens	0-4
18937360-10	2009	In contrast, verapamil stimulation of P-gp ATPase activity was not only enabled by cholesterol but also by alpha-Toc and DPPC.	1,2-Dipalmitoylphosphatidylcholine	121-125	ATP binding cassette subfamily B member 1	Homo sapiens	38-42
18937360-10	2009	In contrast, verapamil stimulation of P-gp ATPase activity was not only enabled by cholesterol but also by alpha-Toc and DPPC.	1,2-Dipalmitoylphosphatidylcholine	121-125	dynein axonemal heavy chain 8	Homo sapiens	43-49
19086158-4	2008	To investigate the binding of the Gla domain of prothrombin fragment 1 (PT1) to anionic lipids in the presence of Ca2+, we have conducted MD simulations of the protein with one and two dipalmitoylphosphatidylserines (DPPS) in a dipalmitoylphosphatidylcholine (DPPC) bilayer membrane.	1,2-Dipalmitoylphosphatidylcholine	260-264	coagulation factor II, thrombin	Homo sapiens	48-59
18503269-5	2008	The binding of MCH to the dpPC-water interface had a K d = 930 nM at 10 mN/m.	1,2-Dipalmitoylphosphatidylcholine	26-30	pro-melanin concentrating hormone	Homo sapiens	15-18
18708453-2	2008	From the film balance studies, we observe that the isotherms of pure DPPC and SP-B/DPPC mixtures very nearly overlay one another at very high pressures, suggesting that the SP-B is being excluded from the film.	1,2-Dipalmitoylphosphatidylcholine	69-73	surfactant protein B	Homo sapiens	173-177
18708453-2	2008	From the film balance studies, we observe that the isotherms of pure DPPC and SP-B/DPPC mixtures very nearly overlay one another at very high pressures, suggesting that the SP-B is being excluded from the film.	1,2-Dipalmitoylphosphatidylcholine	83-87	surfactant protein B	Homo sapiens	173-177
18708453-8	2008	Only a small amount of DPPC appears to be associated with the squeezed out SP-B.	1,2-Dipalmitoylphosphatidylcholine	23-27	surfactant protein B	Homo sapiens	75-79
18694722-4	2008	SP-B(59-80) forms an amphipathic helix which alters lipid organization and acyl chain dynamics in fluid lamellar phase 4:1 DPPC:POPG and 3:1 POPC:POPG MLVs.	1,2-Dipalmitoylphosphatidylcholine	123-127	surfactant protein B	Homo sapiens	0-4
18694722-5	2008	At higher levels of SP-B(59-80) in the POPC:POPG lipid system a transition to a nonlamellar phase is observed while DPPC:POPG mixtures remain in a lamellar phase.	1,2-Dipalmitoylphosphatidylcholine	116-120	surfactant protein B	Homo sapiens	20-24
18694722-6	2008	Deuterium NMR shows an increase in acyl chain order in DPPC:POPG MLVs on addition of SP-B(59-80); in POPC:POPG MLVs, acyl chain order parameters decrease.	1,2-Dipalmitoylphosphatidylcholine	55-59	surfactant protein B	Homo sapiens	85-89
18694722-7	2008	Our results indicate SP-B(59-80) penetrates deeply into DPPC:POPG bilayers and binds more peripherally to POPC:POPG bilayers.	1,2-Dipalmitoylphosphatidylcholine	56-60	surfactant protein B	Homo sapiens	21-25
18621014-2	2008	In particular, the interaction of hIAPP and its rat isoform (rIAPP) with zwitterionic dipalmitoyl-phosphatidylcholine (DPPC), negatively charged dipalmitoyl-phosphatidylserine (DPPS) vesicles and with a 3:1 mixtures of them, has been studied in the presence of Ca(2+) ions.	1,2-Dipalmitoylphosphatidylcholine	86-117	islet amyloid polypeptide	Homo sapiens	34-39
18621014-2	2008	In particular, the interaction of hIAPP and its rat isoform (rIAPP) with zwitterionic dipalmitoyl-phosphatidylcholine (DPPC), negatively charged dipalmitoyl-phosphatidylserine (DPPS) vesicles and with a 3:1 mixtures of them, has been studied in the presence of Ca(2+) ions.	1,2-Dipalmitoylphosphatidylcholine	86-117	islet amyloid polypeptide	Rattus norvegicus	61-66
18621014-2	2008	In particular, the interaction of hIAPP and its rat isoform (rIAPP) with zwitterionic dipalmitoyl-phosphatidylcholine (DPPC), negatively charged dipalmitoyl-phosphatidylserine (DPPS) vesicles and with a 3:1 mixtures of them, has been studied in the presence of Ca(2+) ions.	1,2-Dipalmitoylphosphatidylcholine	119-123	islet amyloid polypeptide	Homo sapiens	34-39
18621014-2	2008	In particular, the interaction of hIAPP and its rat isoform (rIAPP) with zwitterionic dipalmitoyl-phosphatidylcholine (DPPC), negatively charged dipalmitoyl-phosphatidylserine (DPPS) vesicles and with a 3:1 mixtures of them, has been studied in the presence of Ca(2+) ions.	1,2-Dipalmitoylphosphatidylcholine	119-123	islet amyloid polypeptide	Rattus norvegicus	61-66
18621014-3	2008	The experiments have evidenced that amorphous, soluble hIAPP assemblies interact with the hydrophobic core of DPPC bilayers.	1,2-Dipalmitoylphosphatidylcholine	110-114	islet amyloid polypeptide	Homo sapiens	55-60
18533723-12	2008	The populations of conformations with relatively open inter-domain angles, as well as large fluctuations of this coordinate in DPPC bi-layers allow the N-terminal helix to come into contact with the PLB binding site on the calcium ATPase.	1,2-Dipalmitoylphosphatidylcholine	127-131	phospholamban	Homo sapiens	199-202
18296035-4	2008	FB1 (0-81.4 microM), decreased in a dose-dependent manner, the fluorescence anisotropy of TMA-DPH (from 0.349+/-0.003 to 0.1720+/-0.0035) in dpPC bilayers, whilst no differences were registered with DPH.	1,2-Dipalmitoylphosphatidylcholine	141-145	TCF3 fusion partner	Homo sapiens	0-3
18296035-6	2008	FB1 increased the surface potential of dpPC and dpPC:DOTAP monolayers and decreased that of dpPC:dpPA.	1,2-Dipalmitoylphosphatidylcholine	39-43	TCF3 fusion partner	Homo sapiens	0-3
18296035-6	2008	FB1 increased the surface potential of dpPC and dpPC:DOTAP monolayers and decreased that of dpPC:dpPA.	1,2-Dipalmitoylphosphatidylcholine	48-52	TCF3 fusion partner	Homo sapiens	0-3
18296035-6	2008	FB1 increased the surface potential of dpPC and dpPC:DOTAP monolayers and decreased that of dpPC:dpPA.	1,2-Dipalmitoylphosphatidylcholine	48-52	TCF3 fusion partner	Homo sapiens	0-3
18083768-5	2008	Amantadine, an inhibitor of clathrin and, thus, receptor-mediated endocytosis via clathrin-coated pits, decreased basal [(3)H]DPPC uptake by 70% in SP-A +/+ but only by 20% in SP-A -/- lung, data compatible with an SP-A/receptor-regulated lipid clearance pathway in the SP-A +/+ mice.	1,2-Dipalmitoylphosphatidylcholine	126-130	surfactant associated protein A1	Mus musculus	148-152
18339301-10	2008	The effect of SP-C N-terminal peptides on the chain flexibility gradient of DPPC and DPPG bilayers is consistent with the existence of a peptide-promoted interdigitated phase at temperatures below the main gel-to-liquid-crystalline phase transition.	1,2-Dipalmitoylphosphatidylcholine	76-80	surfactant protein C	Homo sapiens	14-18
18355441-0	2008	DPPC regulates COX-2 expression in monocytes via phosphorylation of CREB.	1,2-Dipalmitoylphosphatidylcholine	0-4	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	15-20
18355441-0	2008	DPPC regulates COX-2 expression in monocytes via phosphorylation of CREB.	1,2-Dipalmitoylphosphatidylcholine	0-4	cAMP responsive element binding protein 1	Homo sapiens	68-72
18355441-5	2008	Further, DPPC increased the phosphorylation of the cyclic AMP response element binding protein (CREB; an important nuclear transcription factor important in regulating COX-2 expression).	1,2-Dipalmitoylphosphatidylcholine	9-13	cAMP responsive element binding protein 1	Homo sapiens	96-100
18355441-5	2008	Further, DPPC increased the phosphorylation of the cyclic AMP response element binding protein (CREB; an important nuclear transcription factor important in regulating COX-2 expression).	1,2-Dipalmitoylphosphatidylcholine	9-13	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	168-173
18355441-7	2008	This study provides new evidence for the anti-inflammatory activity of DPPC and that this activity is at least in part mediated via CREB activation of COX-2.	1,2-Dipalmitoylphosphatidylcholine	71-75	cAMP responsive element binding protein 1	Homo sapiens	132-136
18355441-7	2008	This study provides new evidence for the anti-inflammatory activity of DPPC and that this activity is at least in part mediated via CREB activation of COX-2.	1,2-Dipalmitoylphosphatidylcholine	71-75	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	151-156
18234820-3	2008	Activation of phospholipase A(2) (PLA(2)) by ternary model membranes with three components (DOPC/DPPC/Cholesterol) can potentially change the domain structure by preferential hydrolysis of the phospholipids.	1,2-Dipalmitoylphosphatidylcholine	97-101	phospholipase A2 group IB	Homo sapiens	14-32
18234820-3	2008	Activation of phospholipase A(2) (PLA(2)) by ternary model membranes with three components (DOPC/DPPC/Cholesterol) can potentially change the domain structure by preferential hydrolysis of the phospholipids.	1,2-Dipalmitoylphosphatidylcholine	97-101	phospholipase A2 group IB	Homo sapiens	34-40
18369576-3	2008	RESULTS: TNF-alpha and IL-1beta secretion and nitric oxide (NO) formation following LPS stimulation were inhibited by treatment with surfactants or DPPC.	1,2-Dipalmitoylphosphatidylcholine	148-152	tumor necrosis factor	Rattus norvegicus	9-18
18369576-3	2008	RESULTS: TNF-alpha and IL-1beta secretion and nitric oxide (NO) formation following LPS stimulation were inhibited by treatment with surfactants or DPPC.	1,2-Dipalmitoylphosphatidylcholine	148-152	interleukin 1 beta	Rattus norvegicus	23-31
17890383-2	2008	Low levels (3.7 mol % Au/lipid, 0.98% wt/wt) markedly inhibited adsorption of a semisynthetic pulmonary surfactant (dipalmitoyl-phosphatidylcholine (DPPC)/palmitoyl-oleoyl-phosphatidylglycerol/surfactant protein B (SP-B); 70:30:1 wt %).	1,2-Dipalmitoylphosphatidylcholine	116-147	surfactant protein B	Homo sapiens	193-213
17890383-2	2008	Low levels (3.7 mol % Au/lipid, 0.98% wt/wt) markedly inhibited adsorption of a semisynthetic pulmonary surfactant (dipalmitoyl-phosphatidylcholine (DPPC)/palmitoyl-oleoyl-phosphatidylglycerol/surfactant protein B (SP-B); 70:30:1 wt %).	1,2-Dipalmitoylphosphatidylcholine	116-147	surfactant protein B	Homo sapiens	215-219
18225945-3	2008	To address the mechanical fundamentals of nAChR gating, both conventional molecular dynamics (CMD) and steered rotation molecular dynamics (SRMD) simulations have been conducted on the cryo-electron microscopy (cryo-EM) structure of nAChR embedded in a dipalmitoylphosphatidylcholine (DPPC) bilayer and water molecules.	1,2-Dipalmitoylphosphatidylcholine	253-283	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	233-238
18083768-10	2008	These data are compatible with a major role for receptor-mediated endocytosis of DPPC by granular pneumocytes, a process critically dependent on SP-A.	1,2-Dipalmitoylphosphatidylcholine	81-85	surfactant associated protein A1	Mus musculus	145-149
18225945-3	2008	To address the mechanical fundamentals of nAChR gating, both conventional molecular dynamics (CMD) and steered rotation molecular dynamics (SRMD) simulations have been conducted on the cryo-electron microscopy (cryo-EM) structure of nAChR embedded in a dipalmitoylphosphatidylcholine (DPPC) bilayer and water molecules.	1,2-Dipalmitoylphosphatidylcholine	285-289	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	233-238
17668276-4	2007	For this purpose, a strategy was pursued in which a homology model of the hH(3)R based on the crystal structure of bovine rhodopsin was generated and refined by molecular dynamics simulations in a dipalmitoylphosphatidylcholine (DPPC)/water membrane mimic before the resulting binding pocket was used for high-throughput docking using the program GOLD.	1,2-Dipalmitoylphosphatidylcholine	197-227	rhodopsin	Bos taurus	122-131
17662236-3	2007	In turn, LL-37 leads to a disintegration of the lamellar organization of zwitterionic dipalmitoyl-phosphatidylcholine (DPPC) into disk-like micelles.	1,2-Dipalmitoylphosphatidylcholine	119-123	cathelicidin antimicrobial peptide	Homo sapiens	9-14
17897666-1	2007	We report the effect of N-nitrosodiethylamine (NDA) on the interaction between bovine serum albumin (BSA) and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine monolayers (DPPC) at the air-water interface.	1,2-Dipalmitoylphosphatidylcholine	166-170	albumin	Homo sapiens	86-99
17693477-0	2007	Surfactant protein A forms extensive lattice-like structures on 1,2-dipalmitoylphosphatidylcholine/rough-lipopolysaccharide-mixed monolayers.	1,2-Dipalmitoylphosphatidylcholine	64-98	surfactant protein A1	Homo sapiens	0-20
17693477-1	2007	Due to the inhalation of airborne particles containing bacterial lipopolysaccharide (LPS), these molecules might incorporate into the 1,2-dipalmitoylphosphatidylcholine (DPPC)-rich monolayer and interact with surfactant protein A (SP-A), the major surfactant protein component involved in host defense.	1,2-Dipalmitoylphosphatidylcholine	170-174	surfactant protein A1	Homo sapiens	209-229
17693477-1	2007	Due to the inhalation of airborne particles containing bacterial lipopolysaccharide (LPS), these molecules might incorporate into the 1,2-dipalmitoylphosphatidylcholine (DPPC)-rich monolayer and interact with surfactant protein A (SP-A), the major surfactant protein component involved in host defense.	1,2-Dipalmitoylphosphatidylcholine	170-174	surfactant protein A1	Homo sapiens	231-235
17693477-2	2007	In this study, epifluorescence microscopy combined with a surface balance was used to examine the interaction of SP-A with mixed monolayers of DPPC/rough LPS (Re-LPS).	1,2-Dipalmitoylphosphatidylcholine	143-147	surfactant protein A1	Homo sapiens	113-117
17693477-6	2007	SP-A interacted strongly with Re-LPS and promoted the formation of DPPC-rich solid domains.	1,2-Dipalmitoylphosphatidylcholine	67-71	surfactant protein A1	Homo sapiens	0-4
17693477-7	2007	Fluorescently labeled Texas red-SP-A accumulated at the fluid-solid boundary regions and formed networks of interconnected filaments in the fluid phase of DPPC/Re-LPS monolayers in a Ca(2+)-independent manner.	1,2-Dipalmitoylphosphatidylcholine	155-159	surfactant protein A1	Homo sapiens	32-36
17929861-2	2007	In this paper, we use large-scale molecular dynamics simulations to investigate the position and behavior of nitroxide spin labels attached to stearic acid molecules in dipalmitoylphosphatidylcholine (DPPC) bilayers.	1,2-Dipalmitoylphosphatidylcholine	169-199	spindlin 1	Homo sapiens	119-123
17929861-2	2007	In this paper, we use large-scale molecular dynamics simulations to investigate the position and behavior of nitroxide spin labels attached to stearic acid molecules in dipalmitoylphosphatidylcholine (DPPC) bilayers.	1,2-Dipalmitoylphosphatidylcholine	201-205	spindlin 1	Homo sapiens	119-123
17513378-8	2007	The phase behavior effect of the lipids mainly outperforms the electrostatic interactions between DPPG and SP-B, leading to a more passively achieved colocalization of DPPC and SP-B.	1,2-Dipalmitoylphosphatidylcholine	168-172	surfactant protein B	Homo sapiens	107-111
17668276-4	2007	For this purpose, a strategy was pursued in which a homology model of the hH(3)R based on the crystal structure of bovine rhodopsin was generated and refined by molecular dynamics simulations in a dipalmitoylphosphatidylcholine (DPPC)/water membrane mimic before the resulting binding pocket was used for high-throughput docking using the program GOLD.	1,2-Dipalmitoylphosphatidylcholine	197-227	histamine receptor H3	Homo sapiens	74-80
17668276-4	2007	For this purpose, a strategy was pursued in which a homology model of the hH(3)R based on the crystal structure of bovine rhodopsin was generated and refined by molecular dynamics simulations in a dipalmitoylphosphatidylcholine (DPPC)/water membrane mimic before the resulting binding pocket was used for high-throughput docking using the program GOLD.	1,2-Dipalmitoylphosphatidylcholine	229-233	histamine receptor H3	Homo sapiens	74-80
17668276-4	2007	For this purpose, a strategy was pursued in which a homology model of the hH(3)R based on the crystal structure of bovine rhodopsin was generated and refined by molecular dynamics simulations in a dipalmitoylphosphatidylcholine (DPPC)/water membrane mimic before the resulting binding pocket was used for high-throughput docking using the program GOLD.	1,2-Dipalmitoylphosphatidylcholine	229-233	rhodopsin	Bos taurus	122-131
17308333-0	2007	Apolipoprotein E*dipalmitoylphosphatidylcholine particles are ellipsoidal in solution.	1,2-Dipalmitoylphosphatidylcholine	17-47	apolipoprotein E	Homo sapiens	0-16
17408589-1	2007	The structure and dynamics of a single GM1 (Gal5-beta1,3-GalNAc4-beta1,4-(NeuAc3-alpha2,3)-Gal2-beta1,4-Glc1-beta1,1-Cer) embedded in a DPPC bilayer have been studied by MD simulations.	1,2-Dipalmitoylphosphatidylcholine	136-140	galectin 2	Homo sapiens	91-95
17408294-5	2007	The addition of DPPC vesicles into these unstable FB dispersions reversed FB aggregation and precipitation and produced stable translucent microdispersions.	1,2-Dipalmitoylphosphatidylcholine	16-20	fibrinogen beta chain	Homo sapiens	50-52
17277191-5	2007	The free energy of association between dipalmitoylphosphatidylserines in the environment of dipalmitoylphosphatidylcholines has been calculated by using a novel approach to the dual topology technique of the PS-PC hybrid.	1,2-Dipalmitoylphosphatidylcholine	92-123	surfactant protein C	Homo sapiens	208-213
17308333-5	2007	In contrast to a widely accepted discoidal model of apoA-I bound to dimyristoylphosphatidylcholine, which is based on solution studies, an X-ray diffraction study of apoE bound to dipalmitoylphosphatidylcholine (DPPC) indicated that apoE*DPPC particles are quasi-spheroidal and that the packing of the phospholipid core is similar to a micelle.	1,2-Dipalmitoylphosphatidylcholine	180-210	apolipoprotein E	Homo sapiens	166-170
17308333-6	2007	Using small-angle X-ray scattering, we show that apoE*DPPC particles in solution are ellipsoidal and that the shape of the phospholipid core is compatible with a twisted-bilayer model.	1,2-Dipalmitoylphosphatidylcholine	54-58	apolipoprotein E	Homo sapiens	49-53
17166234-5	2007	These changes in surfactant were associated with co-ordinate reductions in mRNAs and immunoreactive levels for CTP: phosphocholine cytidylyltransferase (CCTalpha), the rate-regulatory enzyme required for DPPC synthesis.	1,2-Dipalmitoylphosphatidylcholine	204-208	phosphate cytidylyltransferase 1, choline, alpha isoform	Mus musculus	153-161
17269123-0	2007	Effect of different treatments of long-range interactions and sampling conditions in molecular dynamic simulations of rhodopsin embedded in a dipalmitoyl phosphatidylcholine bilayer.	1,2-Dipalmitoylphosphatidylcholine	142-173	rhodopsin	Bos taurus	118-127
17269123-2	2007	Accordingly, the present work reports the analysis of different simulations of bovine rhodopsin embedded in a dipalmitoyl phosphatidylcholine (DPPC) lipid bilayer using two different sampling conditions and two different approaches for the treatment of long-range electrostatic interactions.	1,2-Dipalmitoylphosphatidylcholine	110-141	rhodopsin	Bos taurus	86-95
17269123-2	2007	Accordingly, the present work reports the analysis of different simulations of bovine rhodopsin embedded in a dipalmitoyl phosphatidylcholine (DPPC) lipid bilayer using two different sampling conditions and two different approaches for the treatment of long-range electrostatic interactions.	1,2-Dipalmitoylphosphatidylcholine	143-147	rhodopsin	Bos taurus	86-95
17260960-8	2007	Using this method, it could be demonstrated that in the presence of HA-PLTP, but not LA-PLTP, [14C]DPPC was transferred from small unilamellar vesicles (SUV) to acceptor HDL3 molecules.	1,2-Dipalmitoylphosphatidylcholine	99-103	phospholipid transfer protein	Homo sapiens	71-75
17051367-5	2007	Native SP-C added to DPPC/DPPG monolayers (molar ratio 80:20) induced the formation of the surface confined reservoir independent of its palmitoylation degree.	1,2-Dipalmitoylphosphatidylcholine	21-25	surfactant protein C	Homo sapiens	7-11
17286427-1	2007	Infrared reflection absorption spectroscopy (IRRAS) and surface plasmon resonance (SPR) techniques have been employed to investigate human serum albumin (HSA) binding to binary monolayers of zwitterionic dipalmitoylphosphatidylcholine (DPPC) and cationic dioctadecyldimethylammonium bromide (DOMA).	1,2-Dipalmitoylphosphatidylcholine	204-234	albumin	Homo sapiens	139-152
17274601-4	2007	All Pin-b types showed evidence of interaction with DPPC films, detected as changes in surface pressure (5.6 +/- 1.1 mN m-1); however, no protein peaks were detected in the ER-FTIR spectra, which indicated that the interaction was via penetration with limited adsorption at the lipid/water interface.	1,2-Dipalmitoylphosphatidylcholine	52-56	LOC543301	Triticum aestivum	4-9
17260960-8	2007	Using this method, it could be demonstrated that in the presence of HA-PLTP, but not LA-PLTP, [14C]DPPC was transferred from small unilamellar vesicles (SUV) to acceptor HDL3 molecules.	1,2-Dipalmitoylphosphatidylcholine	99-103	HDL3	Homo sapiens	170-174
17052685-3	2007	As a model, we have examined the interaction of Abeta(1-42) with phase separated DOPC/DPPC lipid bilayers using a combination of atomic force microscopy (AFM) and total internal reflection fluorescence microscopy (TIRF).	1,2-Dipalmitoylphosphatidylcholine	86-90	amyloid beta precursor protein	Homo sapiens	48-53
17052685-4	2007	AFM images show that addition of Abeta to preformed supported bilayers leads to accumulation of small peptide aggregates exclusively on the gel phase DPPC domains.	1,2-Dipalmitoylphosphatidylcholine	150-154	amyloid beta precursor protein	Homo sapiens	33-38
17126307-8	2007	Akt and ERK phosphorylation was increased following ePPC by 4.5+/-0.5 and 1.9+/-0.6 fold, respectively (p < 0.001), and dPPC by 24+/-2.0 and 2.1+/-0.1 fold, respectively (p < 0.001).	1,2-Dipalmitoylphosphatidylcholine	123-127	thymoma viral proto-oncogene 1	Mus musculus	0-3
17126307-8	2007	Akt and ERK phosphorylation was increased following ePPC by 4.5+/-0.5 and 1.9+/-0.6 fold, respectively (p < 0.001), and dPPC by 24+/-2.0 and 2.1+/-0.1 fold, respectively (p < 0.001).	1,2-Dipalmitoylphosphatidylcholine	123-127	mitogen-activated protein kinase 1	Mus musculus	8-11
17128993-8	2006	Both SP-ADEL and SP-AINS mutants as well as wild-type SP-A bound to liposomes containing dipalmitoylphosphatidylcholine and galactosylceramide at equivalent levels, but the abilities of the mutants to induce phospholipid liposome aggregation were significantly less developed than that of the wild type.	1,2-Dipalmitoylphosphatidylcholine	89-119	surfactant protein A1	Homo sapiens	5-9
17099081-6	2007	During both logarithmic and stationary phases of growth, the physiologically relevant phospholipids, dipalmitoyl phosphatidylcholine (DPPC) and dioleoyl phosphatidylcholine, were taken up and metabolized via PLB1.	1,2-Dipalmitoylphosphatidylcholine	101-132	phospholipase B1	Homo sapiens	208-212
17181183-0	2006	Spin-labeled alkylphospholipids in a dipalmitoylphosphatidylcholine bilayer: molecular dynamics simulations.	1,2-Dipalmitoylphosphatidylcholine	37-67	spindlin 1	Homo sapiens	0-4
16984129-4	2006	Here, we report that liposomes made from a new thiourea lipid, DPPC, and a lipid bearing an RGD ligand allowed very efficient entry of the lipopolythioureas into integrin alpha(v)beta(3) expressing cells.	1,2-Dipalmitoylphosphatidylcholine	63-67	integrin subunit alpha V	Homo sapiens	162-185
16939223-8	2006	RPE membranes containing LRAT transfer palmitoyl groups from radiolabeled [1-(14)C]-l-alpha-dipalmitoyl diphosphatidylcholine (DPPC) to RPE65.	1,2-Dipalmitoylphosphatidylcholine	127-131	lecithin retinol acyltransferase	Homo sapiens	25-29
16939223-8	2006	RPE membranes containing LRAT transfer palmitoyl groups from radiolabeled [1-(14)C]-l-alpha-dipalmitoyl diphosphatidylcholine (DPPC) to RPE65.	1,2-Dipalmitoylphosphatidylcholine	127-131	retinoid isomerohydrolase RPE65	Homo sapiens	136-141
17078651-4	2006	Comparison of NPY associated with zwitterionic DPPC and with anionic DMPS suggests that electrostatic attraction plays a major role for peptide binding to the membrane surface.	1,2-Dipalmitoylphosphatidylcholine	47-51	neuropeptide Y	Homo sapiens	14-17
16831006-4	2006	For a mixed DPPC/fibrinogen layer at the interface, the amide I RA intensity-area hysteresis curves suggest that the fibrinogen molecules were expelled from the interface upon compression, apparently because of the presence of insoluble DPPC molecules.	1,2-Dipalmitoylphosphatidylcholine	12-16	fibrinogen beta chain	Homo sapiens	117-127
17025673-3	2006	The effects of concentration of gadolinium ions Gd3+ on DPPC unilamellar vesicles in aqueous media were studied by different techniques.	1,2-Dipalmitoylphosphatidylcholine	56-60	GRDX	Homo sapiens	48-51
16831006-4	2006	For a mixed DPPC/fibrinogen layer at the interface, the amide I RA intensity-area hysteresis curves suggest that the fibrinogen molecules were expelled from the interface upon compression, apparently because of the presence of insoluble DPPC molecules.	1,2-Dipalmitoylphosphatidylcholine	237-241	fibrinogen beta chain	Homo sapiens	17-27
16831006-4	2006	For a mixed DPPC/fibrinogen layer at the interface, the amide I RA intensity-area hysteresis curves suggest that the fibrinogen molecules were expelled from the interface upon compression, apparently because of the presence of insoluble DPPC molecules.	1,2-Dipalmitoylphosphatidylcholine	237-241	fibrinogen beta chain	Homo sapiens	117-127
16831006-5	2006	The squeeze-out of fibrinogen evidently removed a pronounced amount of DPPC from the interface, as judged from the corresponding nu(a)-CH2 intensity and wavenumber data.	1,2-Dipalmitoylphosphatidylcholine	71-75	fibrinogen beta chain	Homo sapiens	19-29
16831006-7	2006	With the in situ IRRAS analysis of the mixed layer behavior at the interface, the induced loss of DPPC by fibrinogen expulsion from the compressed interface and the dominant adsorption of fibrinogen to the expanded interface were clearly demonstrated.	1,2-Dipalmitoylphosphatidylcholine	98-102	fibrinogen beta chain	Homo sapiens	106-116
16815092-9	2006	These results indicate increased DPPC degradation and synthesis by the reacylation pathway with Prdx6 overexpression and provide additional evidence that the PLA(2) activity of Prdx6 has an important role in lung surfactant turnover.	1,2-Dipalmitoylphosphatidylcholine	33-37	peroxiredoxin 6	Mus musculus	96-101
16815092-9	2006	These results indicate increased DPPC degradation and synthesis by the reacylation pathway with Prdx6 overexpression and provide additional evidence that the PLA(2) activity of Prdx6 has an important role in lung surfactant turnover.	1,2-Dipalmitoylphosphatidylcholine	33-37	peroxiredoxin 6	Mus musculus	177-182
16777057-2	2006	GLTP can catalyze the transfer of a fluorescently labeled GSL, anthrylvinyl-galactosylceramide (AV-GalCer), from vesicles composed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine and dipalmitoylphosphatidylcholine matrices, but not from vesicles prepared from N-palmitoylsphingomyelin, regardless of the cholesterol content of the vesicles.	1,2-Dipalmitoylphosphatidylcholine	187-217	glycolipid transfer protein	Homo sapiens	0-4
16732662-3	2006	Four moieties of the DPPC molecule are probed by BBSFG: the terminal methyl (CD3) groups of the tails, the methylene (CD2) groups of the tails, the choline methyls (CH3) in the headgroup, and the phosphate in the headgroup.	1,2-Dipalmitoylphosphatidylcholine	21-25	CD2 molecule	Homo sapiens	118-121
16777057-2	2006	GLTP can catalyze the transfer of a fluorescently labeled GSL, anthrylvinyl-galactosylceramide (AV-GalCer), from vesicles composed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine and dipalmitoylphosphatidylcholine matrices, but not from vesicles prepared from N-palmitoylsphingomyelin, regardless of the cholesterol content of the vesicles.	1,2-Dipalmitoylphosphatidylcholine	187-217	cathepsin A	Homo sapiens	58-61
16511521-2	2006	CTP:phosphocholine cytidylyltransferase (CCTalpha) is the rate-limiting enzyme required for the biosynthesis of dipalmitoylphosphatidylcholine (DPPC), the major phospholipid of surfactant.	1,2-Dipalmitoylphosphatidylcholine	112-142	phosphate cytidylyltransferase 1, choline, alpha isoform	Mus musculus	0-39
16511521-2	2006	CTP:phosphocholine cytidylyltransferase (CCTalpha) is the rate-limiting enzyme required for the biosynthesis of dipalmitoylphosphatidylcholine (DPPC), the major phospholipid of surfactant.	1,2-Dipalmitoylphosphatidylcholine	112-142	phosphate cytidylyltransferase 1, choline, alpha isoform	Mus musculus	41-49
16511521-2	2006	CTP:phosphocholine cytidylyltransferase (CCTalpha) is the rate-limiting enzyme required for the biosynthesis of dipalmitoylphosphatidylcholine (DPPC), the major phospholipid of surfactant.	1,2-Dipalmitoylphosphatidylcholine	144-148	phosphate cytidylyltransferase 1, choline, alpha isoform	Mus musculus	0-39
16511521-2	2006	CTP:phosphocholine cytidylyltransferase (CCTalpha) is the rate-limiting enzyme required for the biosynthesis of dipalmitoylphosphatidylcholine (DPPC), the major phospholipid of surfactant.	1,2-Dipalmitoylphosphatidylcholine	144-148	phosphate cytidylyltransferase 1, choline, alpha isoform	Mus musculus	41-49
16511521-5	2006	Pseudomonas aeruginosa (PA103) decreased DPPC synthesis, in part, via calpain-mediated degradation of CCTalpha.	1,2-Dipalmitoylphosphatidylcholine	41-45	phosphate cytidylyltransferase 1, choline, alpha isoform	Mus musculus	102-110
16511521-8	2006	The studies suggest that augmentation of DPPC synthesis via gene delivery of CCTalpha can attenuate impaired lung function in surfactant-deficient states such as bacterial sepsis.	1,2-Dipalmitoylphosphatidylcholine	41-45	phosphate cytidylyltransferase 1, choline, alpha isoform	Mus musculus	77-85
17118794-1	2006	Multifunctional transmembrane-building blocks with recognition sites for adrenaline on one end and the reaction partners for an SN2 reaction on the opposite end have been embedded in DPPC-liposomes.	1,2-Dipalmitoylphosphatidylcholine	183-187	solute carrier family 38 member 5	Homo sapiens	128-131
16115641-2	2006	For FB/DPPC mixtures with 750 ppm (0.075 wt%) FB and 1000 ppm (0.10 wt%) DPPC, the tension behavior was found to be similar to that of FB when alone, even with DPPC and FB being at the interface.	1,2-Dipalmitoylphosphatidylcholine	7-11	fibrinogen beta chain	Homo sapiens	46-48
16115641-2	2006	For FB/DPPC mixtures with 750 ppm (0.075 wt%) FB and 1000 ppm (0.10 wt%) DPPC, the tension behavior was found to be similar to that of FB when alone, even with DPPC and FB being at the interface.	1,2-Dipalmitoylphosphatidylcholine	7-11	fibrinogen beta chain	Homo sapiens	46-48
16115641-2	2006	For FB/DPPC mixtures with 750 ppm (0.075 wt%) FB and 1000 ppm (0.10 wt%) DPPC, the tension behavior was found to be similar to that of FB when alone, even with DPPC and FB being at the interface.	1,2-Dipalmitoylphosphatidylcholine	7-11	fibrinogen beta chain	Homo sapiens	46-48
16115641-2	2006	For FB/DPPC mixtures with 750 ppm (0.075 wt%) FB and 1000 ppm (0.10 wt%) DPPC, the tension behavior was found to be similar to that of FB when alone, even with DPPC and FB being at the interface.	1,2-Dipalmitoylphosphatidylcholine	73-77	fibrinogen beta chain	Homo sapiens	4-6
16115641-2	2006	For FB/DPPC mixtures with 750 ppm (0.075 wt%) FB and 1000 ppm (0.10 wt%) DPPC, the tension behavior was found to be similar to that of FB when alone, even with DPPC and FB being at the interface.	1,2-Dipalmitoylphosphatidylcholine	73-77	fibrinogen beta chain	Homo sapiens	4-6
16115641-3	2006	Thus, FB interferes with adsorption of DPPC and inhibits its surface tension lowering ability.	1,2-Dipalmitoylphosphatidylcholine	39-43	fibrinogen beta chain	Homo sapiens	6-8
16115641-4	2006	When FB protein is introduced in the solution after a DPPC monolayer has formed, the adsorption of FB is inhibited by the DPPC monolayer.	1,2-Dipalmitoylphosphatidylcholine	54-58	fibrinogen beta chain	Homo sapiens	5-7
16115641-4	2006	When FB protein is introduced in the solution after a DPPC monolayer has formed, the adsorption of FB is inhibited by the DPPC monolayer.	1,2-Dipalmitoylphosphatidylcholine	54-58	fibrinogen beta chain	Homo sapiens	99-101
16115641-4	2006	When FB protein is introduced in the solution after a DPPC monolayer has formed, the adsorption of FB is inhibited by the DPPC monolayer.	1,2-Dipalmitoylphosphatidylcholine	122-126	fibrinogen beta chain	Homo sapiens	5-7
16115641-4	2006	When FB protein is introduced in the solution after a DPPC monolayer has formed, the adsorption of FB is inhibited by the DPPC monolayer.	1,2-Dipalmitoylphosphatidylcholine	122-126	fibrinogen beta chain	Homo sapiens	99-101
16115641-5	2006	When a DPPC monolayer is spread onto a solution with a preadsorbed FB layer, the DPPC monolayer excludes FB from the surface and controls the tension behavior with little inhibition by FB.	1,2-Dipalmitoylphosphatidylcholine	7-11	fibrinogen beta chain	Homo sapiens	67-69
16115641-5	2006	When a DPPC monolayer is spread onto a solution with a preadsorbed FB layer, the DPPC monolayer excludes FB from the surface and controls the tension behavior with little inhibition by FB.	1,2-Dipalmitoylphosphatidylcholine	7-11	fibrinogen beta chain	Homo sapiens	105-107
16115641-5	2006	When a DPPC monolayer is spread onto a solution with a preadsorbed FB layer, the DPPC monolayer excludes FB from the surface and controls the tension behavior with little inhibition by FB.	1,2-Dipalmitoylphosphatidylcholine	7-11	fibrinogen beta chain	Homo sapiens	105-107
16115641-5	2006	When a DPPC monolayer is spread onto a solution with a preadsorbed FB layer, the DPPC monolayer excludes FB from the surface and controls the tension behavior with little inhibition by FB.	1,2-Dipalmitoylphosphatidylcholine	81-85	fibrinogen beta chain	Homo sapiens	67-69
16115641-5	2006	When a DPPC monolayer is spread onto a solution with a preadsorbed FB layer, the DPPC monolayer excludes FB from the surface and controls the tension behavior with little inhibition by FB.	1,2-Dipalmitoylphosphatidylcholine	81-85	fibrinogen beta chain	Homo sapiens	105-107
16115641-5	2006	When a DPPC monolayer is spread onto a solution with a preadsorbed FB layer, the DPPC monolayer excludes FB from the surface and controls the tension behavior with little inhibition by FB.	1,2-Dipalmitoylphosphatidylcholine	81-85	fibrinogen beta chain	Homo sapiens	105-107
16115641-6	2006	When a DPPC dispersion is introduced with the Trurnit method, or sprayed dropwise, onto an aqueous FB/DPPC surfaces, the DPPC layer formed on the surface prevents the adsorption of FB and dominates the surface tension behavior.	1,2-Dipalmitoylphosphatidylcholine	7-11	fibrinogen beta chain	Homo sapiens	99-101
16115641-6	2006	When a DPPC dispersion is introduced with the Trurnit method, or sprayed dropwise, onto an aqueous FB/DPPC surfaces, the DPPC layer formed on the surface prevents the adsorption of FB and dominates the surface tension behavior.	1,2-Dipalmitoylphosphatidylcholine	7-11	fibrinogen beta chain	Homo sapiens	181-183
16115641-6	2006	When a DPPC dispersion is introduced with the Trurnit method, or sprayed dropwise, onto an aqueous FB/DPPC surfaces, the DPPC layer formed on the surface prevents the adsorption of FB and dominates the surface tension behavior.	1,2-Dipalmitoylphosphatidylcholine	102-106	fibrinogen beta chain	Homo sapiens	181-183
16115641-6	2006	When a DPPC dispersion is introduced with the Trurnit method, or sprayed dropwise, onto an aqueous FB/DPPC surfaces, the DPPC layer formed on the surface prevents the adsorption of FB and dominates the surface tension behavior.	1,2-Dipalmitoylphosphatidylcholine	102-106	fibrinogen beta chain	Homo sapiens	181-183
16278220-0	2006	Model of biologically active apolipoprotein E bound to dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	55-85	apolipoprotein E	Homo sapiens	29-45
15979580-3	2005	The monolayer technique allowed us to define GPI-BIAP interaction with DPPC and POPC, lipids differing only by the presence of one unsaturation in their acyl chains.	1,2-Dipalmitoylphosphatidylcholine	71-75	glucose-6-phosphate isomerase	Bos taurus	45-48
16511213-4	2005	To test this possibility, apoE4 complexed with the phospholipid dipalmitoylphosphatidylcholine was chosen.	1,2-Dipalmitoylphosphatidylcholine	64-94	apolipoprotein E	Homo sapiens	26-31
15961786-4	2005	The present work studies the effect of AEA-induced structural modifications of the dipalmitoylphosphatidylcholine (DPPC) bilayer on phospholipase A2 (PLA2) activity, which is strictly dependent on lipid bilayer features.	1,2-Dipalmitoylphosphatidylcholine	83-113	phospholipase A2 group IB	Homo sapiens	132-148
15961786-4	2005	The present work studies the effect of AEA-induced structural modifications of the dipalmitoylphosphatidylcholine (DPPC) bilayer on phospholipase A2 (PLA2) activity, which is strictly dependent on lipid bilayer features.	1,2-Dipalmitoylphosphatidylcholine	83-113	phospholipase A2 group IB	Homo sapiens	150-154
15961786-4	2005	The present work studies the effect of AEA-induced structural modifications of the dipalmitoylphosphatidylcholine (DPPC) bilayer on phospholipase A2 (PLA2) activity, which is strictly dependent on lipid bilayer features.	1,2-Dipalmitoylphosphatidylcholine	115-119	phospholipase A2 group IB	Homo sapiens	132-148
15961786-4	2005	The present work studies the effect of AEA-induced structural modifications of the dipalmitoylphosphatidylcholine (DPPC) bilayer on phospholipase A2 (PLA2) activity, which is strictly dependent on lipid bilayer features.	1,2-Dipalmitoylphosphatidylcholine	115-119	phospholipase A2 group IB	Homo sapiens	150-154
15979580-4	2005	Meanwhile the exclusion pressures were similar for the two phospholipids, the comparison of the Langmuir isotherms (i.e., pressure/area diagrams) indicates that GPI-BIAP interacted differently with DPPC and POPC monolayers.	1,2-Dipalmitoylphosphatidylcholine	198-202	glucose-6-phosphate isomerase	Bos taurus	161-164
15698751-5	2005	Even though p24-1 is disordered in aqueous solutions, the interaction with dipalmitoyl phosphatidylcholine (DPPC) causes it to adopt an alpha-helix structure, as shown by circular dichroism (CD) data for multilamellar vesicles (MLV).	1,2-Dipalmitoylphosphatidylcholine	75-106	drosha ribonuclease III	Homo sapiens	12-17
15681395-0	2005	Surfactant phospholipid DPPC downregulates monocyte respiratory burst via modulation of PKC.	1,2-Dipalmitoylphosphatidylcholine	24-28	protein kinase C alpha	Homo sapiens	88-91
15681395-6	2005	The effects of DPPC were evaluated on both LPS/zymosan and PMA activation of protein kinase C (PKC), a ubiquitous intracellular kinase, in MM6 cells.	1,2-Dipalmitoylphosphatidylcholine	15-19	protein kinase C alpha	Homo sapiens	95-98
15681395-7	2005	We found that DPPC significantly inhibited the activity of PKC in stimulated cells by 70% (P < 0.01).	1,2-Dipalmitoylphosphatidylcholine	14-18	protein kinase C alpha	Homo sapiens	59-62
15681395-8	2005	Western blotting experiments demonstrated that DPPC was able to attenuate the activation of the PKCdelta isoform but not PKCalpha.	1,2-Dipalmitoylphosphatidylcholine	47-51	protein kinase C delta	Homo sapiens	96-104
15681395-9	2005	These results suggest that DPPC, the major component of pulmonary surfactant, plays a role in modulating leukocyte inflammatory responses in the lung via downregulation of PKC, a mechanism that may involve the PKCdelta isoform.	1,2-Dipalmitoylphosphatidylcholine	27-31	protein kinase C alpha	Homo sapiens	172-175
15681395-9	2005	These results suggest that DPPC, the major component of pulmonary surfactant, plays a role in modulating leukocyte inflammatory responses in the lung via downregulation of PKC, a mechanism that may involve the PKCdelta isoform.	1,2-Dipalmitoylphosphatidylcholine	27-31	protein kinase C delta	Homo sapiens	210-218
15772425-1	2005	Lung surfactant dipalmitoylphosphatidylcholine (DPPC) is endocytosed by alveolar epithelial cells and degraded by lysosomal-type phospholipase A2 (aiPLA2).	1,2-Dipalmitoylphosphatidylcholine	16-46	peroxiredoxin 6	Mus musculus	147-153
15772425-1	2005	Lung surfactant dipalmitoylphosphatidylcholine (DPPC) is endocytosed by alveolar epithelial cells and degraded by lysosomal-type phospholipase A2 (aiPLA2).	1,2-Dipalmitoylphosphatidylcholine	48-52	peroxiredoxin 6	Mus musculus	147-153
15772425-5	2005	Degradation of internalized [3H]DPPC in isolated mouse lungs after endotracheal instillation of unilamellar liposomes labeled with [3H]DPPC was significantly decreased at 2 h in Prdx6-/- mice (13.6 +/- 0.3% vs. 26.8 +/- 0.8% in the wild type), reflected by decreased dpm in the lysophosphatidylcholine and the unsaturated PC fractions.	1,2-Dipalmitoylphosphatidylcholine	32-36	peroxiredoxin 6	Mus musculus	178-183
15772425-5	2005	Degradation of internalized [3H]DPPC in isolated mouse lungs after endotracheal instillation of unilamellar liposomes labeled with [3H]DPPC was significantly decreased at 2 h in Prdx6-/- mice (13.6 +/- 0.3% vs. 26.8 +/- 0.8% in the wild type), reflected by decreased dpm in the lysophosphatidylcholine and the unsaturated PC fractions.	1,2-Dipalmitoylphosphatidylcholine	135-139	peroxiredoxin 6	Mus musculus	178-183
15772425-8	2005	These results confirm an important role for Prdx6 in lung surfactant DPPC degradation and synthesis by the reacylation pathway.	1,2-Dipalmitoylphosphatidylcholine	69-73	peroxiredoxin 6	Mus musculus	44-49
15829349-1	2005	Differential scanning calorimetry has been used to understand the thermodynamics of the interactions of dl-alpha-dipalmitoylphosphatidylcholine (DPPC) with alpha-lactalbumin and the effect of the antioxidant nicotinamide on these interactions.	1,2-Dipalmitoylphosphatidylcholine	145-149	lactalbumin alpha	Homo sapiens	156-173
15829349-5	2005	The thermal unfoldings of alpha-lactalbumin in the presence of DPPC as cosolute also adhered to two-state reversible mechanism.	1,2-Dipalmitoylphosphatidylcholine	63-67	lactalbumin alpha	Homo sapiens	26-43
15698751-5	2005	Even though p24-1 is disordered in aqueous solutions, the interaction with dipalmitoyl phosphatidylcholine (DPPC) causes it to adopt an alpha-helix structure, as shown by circular dichroism (CD) data for multilamellar vesicles (MLV).	1,2-Dipalmitoylphosphatidylcholine	108-112	drosha ribonuclease III	Homo sapiens	12-17
15738465-1	2005	We have performed molecular dynamics simulations of the interactions of the peptide SP-B(1-25), which is a truncated version of the full pulmonary surfactant protein SP-B, with dipalmitoylphosphatidylcholine monolayers, which are the major lipid components of lung surfactant.	1,2-Dipalmitoylphosphatidylcholine	177-207	surfactant protein B	Homo sapiens	84-88
15566157-5	2004	We demonstrated the hydrolysis reaction in DPPC (dipalmitoyl phosphatidylcholine)/DPPS (dipalmitoyl phosphatidylserine)-mixed monolayers by phospholipase A2 by using the system.	1,2-Dipalmitoylphosphatidylcholine	43-47	phospholipase A2 group IB	Homo sapiens	140-156
15628884-5	2005	SP-Br had, however, effects similar to those of native SP-B on the thermotropic properties of dipalmitoylphosphatidylcholine (DPPC) bilayers.	1,2-Dipalmitoylphosphatidylcholine	126-130	surfactant protein B	Homo sapiens	0-4
15628884-6	2005	SP-Br was more effective than native SP-B in promoting interfacial adsorption of phospholipid bilayers into interfacial films, presumably because of its higher structural flexibility, and retained the ability of native SP-B to stabilize DPPC interfacial films compressed to pressures near collapse against spontaneous relaxation.	1,2-Dipalmitoylphosphatidylcholine	237-241	surfactant protein B	Homo sapiens	0-4
15595797-1	2004	We present the results of a fluorescence microscopy study of the interaction of annexin A1 with dipalmitoylphosphatidylcholine (DPPC) monolayers as a function of the lipid monolayer phase and the pH of the aqueous subphase.	1,2-Dipalmitoylphosphatidylcholine	96-126	annexin A1	Homo sapiens	80-90
15595797-1	2004	We present the results of a fluorescence microscopy study of the interaction of annexin A1 with dipalmitoylphosphatidylcholine (DPPC) monolayers as a function of the lipid monolayer phase and the pH of the aqueous subphase.	1,2-Dipalmitoylphosphatidylcholine	128-132	annexin A1	Homo sapiens	80-90
15595797-2	2004	We show that annexin A1-DPPC interaction depends strongly on the domain structure of the DPPC monolayer and only weakly on the subphase pH.	1,2-Dipalmitoylphosphatidylcholine	24-28	annexin A1	Homo sapiens	13-23
15654742-2	2005	Addition of SP-B to liposomes composed of DPPC/PG (7:3) leads to membrane binding, destabilization, and fusion, ultimately resulting in rearrangement of membrane structure.	1,2-Dipalmitoylphosphatidylcholine	42-46	surfactant protein B	Homo sapiens	12-16
15628884-5	2005	SP-Br had, however, effects similar to those of native SP-B on the thermotropic properties of dipalmitoylphosphatidylcholine (DPPC) bilayers.	1,2-Dipalmitoylphosphatidylcholine	94-124	surfactant protein B	Homo sapiens	0-4
15566157-5	2004	We demonstrated the hydrolysis reaction in DPPC (dipalmitoyl phosphatidylcholine)/DPPS (dipalmitoyl phosphatidylserine)-mixed monolayers by phospholipase A2 by using the system.	1,2-Dipalmitoylphosphatidylcholine	49-80	phospholipase A2 group IB	Homo sapiens	140-156
15225660-2	2004	Atomic force microscopy revealed that the C-terminal 9-32 fragment of human calcitonin (hCT (9-32)), free or coupled to enhanced green fluorescent protein (hCT-eGFP) cargo forms aggregates in the DOPC fluid phase in absence of Chl and in the DPPC enriched liquid-ordered phase when Chl is present.	1,2-Dipalmitoylphosphatidylcholine	242-246	calcitonin related polypeptide alpha	Homo sapiens	76-86
15210366-1	2004	Monolayers of mixtures of 1,2-dipalmitoylphosphatidylcholine (DPPC) as the substrate and 1,2-dipalmitoylphosphatidic acid (DPPA) as the product of the hydrolysis reaction catalyzed by phospholipase D (PLD) were investigated in the presence of Ca2+.	1,2-Dipalmitoylphosphatidylcholine	26-60	glycosylphosphatidylinositol specific phospholipase D1	Homo sapiens	184-199
15257902-2	2004	METHODS: Freeze-drying method was used to prepare PPT-DPPC-PL, and the particle morphology, size range, encapsulation efficiency and stability of PPT-DPPC liposome were investigated.	1,2-Dipalmitoylphosphatidylcholine	54-58	tachykinin precursor 1	Homo sapiens	50-53
14504839-0	2004	Perturbation of DPPC bilayers by high concentrations of pulmonary surfactant protein SP-B.	1,2-Dipalmitoylphosphatidylcholine	16-20	surfactant protein B	Homo sapiens	85-89
15209508-4	2004	In HL60 cells, the fractional turnover rate is 34.1 +/- 16.6%/h for 1,2-dipalmitoylglycerophosphocholine (16:0,16:0-GPC), which accounts for approximately 10% of total diacylglycerol turnover.	1,2-Dipalmitoylphosphatidylcholine	68-104	glycophorin C (Gerbich blood group)	Homo sapiens	116-119
14504839-1	2004	Deuterium ((2)H) NMR has been used to observe perturbation of dipalmitoylphosphatidylcholine (DPPC) bilayers by the pulmonary surfactant protein B (SP-B) at concentrations up to 17% (w/w).	1,2-Dipalmitoylphosphatidylcholine	62-92	surfactant protein B	Homo sapiens	126-146
14504839-1	2004	Deuterium ((2)H) NMR has been used to observe perturbation of dipalmitoylphosphatidylcholine (DPPC) bilayers by the pulmonary surfactant protein B (SP-B) at concentrations up to 17% (w/w).	1,2-Dipalmitoylphosphatidylcholine	62-92	surfactant protein B	Homo sapiens	148-152
14504839-1	2004	Deuterium ((2)H) NMR has been used to observe perturbation of dipalmitoylphosphatidylcholine (DPPC) bilayers by the pulmonary surfactant protein B (SP-B) at concentrations up to 17% (w/w).	1,2-Dipalmitoylphosphatidylcholine	94-98	surfactant protein B	Homo sapiens	126-146
14504839-1	2004	Deuterium ((2)H) NMR has been used to observe perturbation of dipalmitoylphosphatidylcholine (DPPC) bilayers by the pulmonary surfactant protein B (SP-B) at concentrations up to 17% (w/w).	1,2-Dipalmitoylphosphatidylcholine	94-98	surfactant protein B	Homo sapiens	148-152
14504839-3	2004	This is consistent with the perturbation of headgroup-deuterated DPPC reported here for bilayers containing 6 and 9% (w/w) SP-B.	1,2-Dipalmitoylphosphatidylcholine	65-69	surfactant protein B	Homo sapiens	123-127
14504839-4	2004	For the higher concentrations of SP-B investigated in the present work, (2)H NMR spectra of DPPC deuterated in both the headgroup and chain display a prominent narrow component consistent with fast, large amplitude reorientation of some labeled lipid.	1,2-Dipalmitoylphosphatidylcholine	92-96	surfactant protein B	Homo sapiens	33-37
14504839-6	2004	The observation of large amplitude lipid reorientation at high SP-B concentration could indicate that SP-B can induce regions of high bilayer curvature and thus provides some insight into local interaction of SP-B with DPPC.	1,2-Dipalmitoylphosphatidylcholine	219-223	surfactant protein B	Homo sapiens	63-67
14504839-6	2004	The observation of large amplitude lipid reorientation at high SP-B concentration could indicate that SP-B can induce regions of high bilayer curvature and thus provides some insight into local interaction of SP-B with DPPC.	1,2-Dipalmitoylphosphatidylcholine	219-223	surfactant protein B	Homo sapiens	102-106
14504839-6	2004	The observation of large amplitude lipid reorientation at high SP-B concentration could indicate that SP-B can induce regions of high bilayer curvature and thus provides some insight into local interaction of SP-B with DPPC.	1,2-Dipalmitoylphosphatidylcholine	219-223	surfactant protein B	Homo sapiens	102-106
14744478-8	2004	DSC study suggested an indication of initial electrostatic stabilization of SOD by DPPC and sucrose, the following lipid perturbation by SOD, and the formation of an inclusion complex, thus minimizing the individual transition peaks of SOD and DPPC.	1,2-Dipalmitoylphosphatidylcholine	83-87	superoxide dismutase 1	Homo sapiens	76-79
15164767-1	2004	Based on the assumption that fatty-acid-binding proteins (FABPs) of the epidermal-type (E-FABP) and heart-type (H-FABP) in murine alveolar type II (TII) cells mediate the synthesis of dipalmitoyl phosphatidylcholine (DPPC), the main surfactant phospholipid, we analysed TII cells isolated from wild-type (wt) and E/H-FABP double-knockout (double-ko) mice.	1,2-Dipalmitoylphosphatidylcholine	184-215	fatty acid binding protein 3, muscle and heart	Mus musculus	112-118
15164767-1	2004	Based on the assumption that fatty-acid-binding proteins (FABPs) of the epidermal-type (E-FABP) and heart-type (H-FABP) in murine alveolar type II (TII) cells mediate the synthesis of dipalmitoyl phosphatidylcholine (DPPC), the main surfactant phospholipid, we analysed TII cells isolated from wild-type (wt) and E/H-FABP double-knockout (double-ko) mice.	1,2-Dipalmitoylphosphatidylcholine	217-221	fatty acid binding protein 3, muscle and heart	Mus musculus	112-118
15164767-8	2004	This indicated that E-FABP and/or H-FABP are involved in the mediation of DPPC synthesis in wt TII cells.	1,2-Dipalmitoylphosphatidylcholine	74-78	fatty acid binding protein 5, epidermal	Mus musculus	20-26
15164767-8	2004	This indicated that E-FABP and/or H-FABP are involved in the mediation of DPPC synthesis in wt TII cells.	1,2-Dipalmitoylphosphatidylcholine	74-78	fatty acid binding protein 3, muscle and heart	Mus musculus	34-40
14744478-8	2004	DSC study suggested an indication of initial electrostatic stabilization of SOD by DPPC and sucrose, the following lipid perturbation by SOD, and the formation of an inclusion complex, thus minimizing the individual transition peaks of SOD and DPPC.	1,2-Dipalmitoylphosphatidylcholine	244-248	superoxide dismutase 1	Homo sapiens	76-79
14744478-10	2004	The surface ESCA analysis of this formulation suggested the absence of SOD on the surface region of the powders, indicating that SOD was well surrounded and protected by DPPC and sucrose.	1,2-Dipalmitoylphosphatidylcholine	170-174	superoxide dismutase 1	Homo sapiens	129-132
14744478-11	2004	Spray drying has been demonstrated to be a feasible process to preserve the activity of SOD in the formulation of DPPC liposomes with sucrose.	1,2-Dipalmitoylphosphatidylcholine	114-118	superoxide dismutase 1	Homo sapiens	88-91
14507703-0	2003	Interaction of pulmonary surfactant protein SP-A with DPPC/egg-PG bilayers.	1,2-Dipalmitoylphosphatidylcholine	54-58	surfactant protein A1	Homo sapiens	44-48
14561475-3	2003	In this study, a binary phase diagram of hydrated mixtures of N-palmitoylethanolamine (NP-E)--an endogenous ligand for the peripheral cannabinoid receptor (CB-2)--with dipalmitoylphosphatidylcholine (DPPC) is established by high-sensitivity differential scanning calorimetry (DSC).	1,2-Dipalmitoylphosphatidylcholine	168-198	cannabinoid receptor 2	Homo sapiens	156-160
14507703-3	2003	Deuterium NMR was used to characterize the perturbation by SP-A, in the presence of 5 mM Ca(2+), of dipalmitoyl phosphatidylcholine (DPPC) properties in DPPC/egg-PG (7:3) bilayers.	1,2-Dipalmitoylphosphatidylcholine	100-131	surfactant protein A1	Homo sapiens	59-63
14507703-3	2003	Deuterium NMR was used to characterize the perturbation by SP-A, in the presence of 5 mM Ca(2+), of dipalmitoyl phosphatidylcholine (DPPC) properties in DPPC/egg-PG (7:3) bilayers.	1,2-Dipalmitoylphosphatidylcholine	133-137	surfactant protein A1	Homo sapiens	59-63
14507703-3	2003	Deuterium NMR was used to characterize the perturbation by SP-A, in the presence of 5 mM Ca(2+), of dipalmitoyl phosphatidylcholine (DPPC) properties in DPPC/egg-PG (7:3) bilayers.	1,2-Dipalmitoylphosphatidylcholine	153-157	surfactant protein A1	Homo sapiens	59-63
14507703-4	2003	Effects of SP-A were uniformly distributed over the observed DPPC population.	1,2-Dipalmitoylphosphatidylcholine	61-65	surfactant protein A1	Homo sapiens	11-15
14507703-5	2003	SP-A reduced DPPC chain orientational order significantly in the gel phase but only slightly in the liquid-crystalline phase.	1,2-Dipalmitoylphosphatidylcholine	13-17	surfactant protein A1	Homo sapiens	0-4
14507703-6	2003	Quadrupole echo decay times for DPPC chain deuterons were sensitive to SP-A in the liquid-crystalline mixture but not in the gel phase.	1,2-Dipalmitoylphosphatidylcholine	32-36	surfactant protein A1	Homo sapiens	71-75
14507703-8	2003	The observed effects of SP-A on DPPC/egg-PG bilayer properties differ from those of the hydrophobic surfactant proteins SP-B and SP-C.	1,2-Dipalmitoylphosphatidylcholine	32-36	surfactant protein A1	Homo sapiens	24-28
14507728-2	2003	To unravel the mechanism involved in these properties, the interaction of puroindoline-a (PIN-a) with dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylglycerol (DPPG) monolayers was studied by coupling Langmuir-Blodgett and imaging techniques.	1,2-Dipalmitoylphosphatidylcholine	102-132	puroindoline	Triticum aestivum	74-88
14507728-2	2003	To unravel the mechanism involved in these properties, the interaction of puroindoline-a (PIN-a) with dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylglycerol (DPPG) monolayers was studied by coupling Langmuir-Blodgett and imaging techniques.	1,2-Dipalmitoylphosphatidylcholine	102-132	puroindoline	Triticum aestivum	90-95
14507728-2	2003	To unravel the mechanism involved in these properties, the interaction of puroindoline-a (PIN-a) with dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylglycerol (DPPG) monolayers was studied by coupling Langmuir-Blodgett and imaging techniques.	1,2-Dipalmitoylphosphatidylcholine	134-138	puroindoline	Triticum aestivum	74-88
14507728-2	2003	To unravel the mechanism involved in these properties, the interaction of puroindoline-a (PIN-a) with dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylglycerol (DPPG) monolayers was studied by coupling Langmuir-Blodgett and imaging techniques.	1,2-Dipalmitoylphosphatidylcholine	134-138	puroindoline	Triticum aestivum	90-95
14507728-5	2003	Confocal laser scanning microscopy and atomic force microscopy showed that PIN-a was mainly inserted in the liquid-expanded phase of the DPPC, where it formed an aggregated protein network and induced the fusion of liquid-condensed domains.	1,2-Dipalmitoylphosphatidylcholine	137-141	puroindoline	Triticum aestivum	75-80
14995453-5	2004	C is shown to be linearly proportional to the monolayer surface viscosity, eta(s), for dipalmitoylphosphatidylcholine monolayers in the condensed phase by comparison to surface viscosity measured by channel viscometry.	1,2-Dipalmitoylphosphatidylcholine	87-117	endothelin receptor type A	Homo sapiens	75-78
14695272-6	2004	Presence of increasing amounts of pulmonary surfactant protein SP-B affected the distribution of the LE and LC regions of DPPC and DPPC/DPPG films both at the microscopic and the nanoscopic level.	1,2-Dipalmitoylphosphatidylcholine	122-126	surfactant protein B	Homo sapiens	63-67
14695272-6	2004	Presence of increasing amounts of pulmonary surfactant protein SP-B affected the distribution of the LE and LC regions of DPPC and DPPC/DPPG films both at the microscopic and the nanoscopic level.	1,2-Dipalmitoylphosphatidylcholine	131-135	surfactant protein B	Homo sapiens	63-67
14695272-10	2004	The effect of SP-B on the nanoscopic structure of the lipid films was greater in DPPC/DPPG than in pure DPPC films, indicating additional contributions of electrostatic lipid-protein interactions.	1,2-Dipalmitoylphosphatidylcholine	81-85	surfactant protein B	Homo sapiens	14-18
14695272-10	2004	The effect of SP-B on the nanoscopic structure of the lipid films was greater in DPPC/DPPG than in pure DPPC films, indicating additional contributions of electrostatic lipid-protein interactions.	1,2-Dipalmitoylphosphatidylcholine	104-108	surfactant protein B	Homo sapiens	14-18
14695272-12	2004	SP-B also formed segregated two-dimensional clusters that were associated with the boundaries between LC microdomains and the LE regions of DPPC and DPPC/DPPG films.	1,2-Dipalmitoylphosphatidylcholine	140-144	surfactant protein B	Homo sapiens	0-4
14695272-12	2004	SP-B also formed segregated two-dimensional clusters that were associated with the boundaries between LC microdomains and the LE regions of DPPC and DPPC/DPPG films.	1,2-Dipalmitoylphosphatidylcholine	149-153	surfactant protein B	Homo sapiens	0-4
14695273-0	2004	Distribution of GD3 in DPPC monolayers: a thermodynamic and atomic force microscopy combined study.	1,2-Dipalmitoylphosphatidylcholine	23-27	GRDX	Homo sapiens	16-19
12676766-0	2003	SP-A is necessary for increased clearance of alveolar DPPC with hyperventilation or secretagogues.	1,2-Dipalmitoylphosphatidylcholine	54-58	surfactant associated protein A1	Mus musculus	0-4
12676766-1	2003	The role of surfactant protein-A (SP-A) in pulmonary uptake and metabolism of [(3)H]dipalmitoylphosphatidylcholine ([(3)H]DPPC) was studied in SP-A gene-targeted mice (SP-A -/-).	1,2-Dipalmitoylphosphatidylcholine	122-126	surfactant associated protein A1	Mus musculus	12-32
12676766-1	2003	The role of surfactant protein-A (SP-A) in pulmonary uptake and metabolism of [(3)H]dipalmitoylphosphatidylcholine ([(3)H]DPPC) was studied in SP-A gene-targeted mice (SP-A -/-).	1,2-Dipalmitoylphosphatidylcholine	122-126	surfactant associated protein A1	Mus musculus	34-38
12676766-4	2003	[(3)H]DPPC uptake increased with CO(2)-induced hyperventilation in wild-type mice (SP-A +/+) but was unchanged in SP-A -/-.	1,2-Dipalmitoylphosphatidylcholine	6-10	surfactant associated protein A1	Mus musculus	83-87
12376341-1	2002	The content-dependent activity of surfactant protein (SP)-B was studied in mixtures with dipalmitoyl phosphatidylcholine (DPPC), synthetic lipids (SL), and purified phospholipids (PPL) from calf lung surfactant extract (CLSE).	1,2-Dipalmitoylphosphatidylcholine	89-120	surfactant protein B	Bos taurus	34-59
12672109-0	2003	Direct observations of the cleavage reaction of an L-DPPC monolayer catalyzed by phospholipase A2 and inhibited by an indole inhibitor at the air/water interface.	1,2-Dipalmitoylphosphatidylcholine	51-57	phospholipase A2 group IB	Homo sapiens	81-97
12672109-1	2003	The enzymatic hydrolysis of an L-dipalmitoylphosphatidylcholine (L-DPPC) monolayer at the air/water interface, catalyzed by phospholipase A(2) (PLA(2)), serves as a model for biospecific interfacial reactions.	1,2-Dipalmitoylphosphatidylcholine	65-71	phospholipase A2 group IB	Homo sapiens	124-142
12672109-1	2003	The enzymatic hydrolysis of an L-dipalmitoylphosphatidylcholine (L-DPPC) monolayer at the air/water interface, catalyzed by phospholipase A(2) (PLA(2)), serves as a model for biospecific interfacial reactions.	1,2-Dipalmitoylphosphatidylcholine	65-71	phospholipase A2 group IB	Homo sapiens	144-150
12676766-6	2003	Lungs degraded 23 +/- 1.2% of internalized [(3)H]DPPC in SP-A +/+ and 36 +/- 0.6% in SP-A -/-; degradation increased with 8-bromoadenosine 3",5"-cyclic monophosphate in SP-A +/+ but was unchanged in SP-A -/-.	1,2-Dipalmitoylphosphatidylcholine	49-53	surfactant associated protein A1	Mus musculus	57-61
12676766-8	2003	Thus SP-A is necessary for lungs to respond to hyperventilation or secretagogues with increased DPPC uptake and also modulates the PLA(2)-mediated degradation of internalized DPPC.	1,2-Dipalmitoylphosphatidylcholine	96-100	surfactant associated protein A1	Mus musculus	5-9
12676766-8	2003	Thus SP-A is necessary for lungs to respond to hyperventilation or secretagogues with increased DPPC uptake and also modulates the PLA(2)-mediated degradation of internalized DPPC.	1,2-Dipalmitoylphosphatidylcholine	175-179	surfactant associated protein A1	Mus musculus	5-9
12676766-8	2003	Thus SP-A is necessary for lungs to respond to hyperventilation or secretagogues with increased DPPC uptake and also modulates the PLA(2)-mediated degradation of internalized DPPC.	1,2-Dipalmitoylphosphatidylcholine	175-179	phospholipase A2, group V	Mus musculus	131-136
12706441-8	2003	We propose that PLB secreted by cryptococci promotes tissue invasion by hydrolysing host phospholipids, such as dipalmitoyl phosphatidyl choline, which is abundant in pulmonary surfactant, and lung cell membrane phospholipids.	1,2-Dipalmitoylphosphatidylcholine	112-144	phospholipase B1	Rattus norvegicus	16-19
16256461-0	2003	Induced removal of dipalmitoyl phosphatidylcholine by the exclusion of fibrinogen from compressed monolayers at air/liquid interfaces.	1,2-Dipalmitoylphosphatidylcholine	19-50	fibrinogen beta chain	Homo sapiens	71-81
16256461-1	2003	The induced removal of dipalmitoyl phosphatidylcholine (DPPC) by the exclusion of fibrinogen from mixed DPPC/fibrinogen monolayers at compressed air/liquid interfaces was analyzed.	1,2-Dipalmitoylphosphatidylcholine	23-54	fibrinogen beta chain	Homo sapiens	82-92
16256461-1	2003	The induced removal of dipalmitoyl phosphatidylcholine (DPPC) by the exclusion of fibrinogen from mixed DPPC/fibrinogen monolayers at compressed air/liquid interfaces was analyzed.	1,2-Dipalmitoylphosphatidylcholine	56-60	fibrinogen beta chain	Homo sapiens	82-92
16256461-1	2003	The induced removal of dipalmitoyl phosphatidylcholine (DPPC) by the exclusion of fibrinogen from mixed DPPC/fibrinogen monolayers at compressed air/liquid interfaces was analyzed.	1,2-Dipalmitoylphosphatidylcholine	56-60	fibrinogen beta chain	Homo sapiens	109-119
16256461-4	2003	For mixed monolayers of DPPC with fibrinogen, the fibrinogen molecules were expelled from the interface upon compression due to the presence of insoluble DPPC molecules.	1,2-Dipalmitoylphosphatidylcholine	24-28	fibrinogen beta chain	Homo sapiens	34-44
16256461-4	2003	For mixed monolayers of DPPC with fibrinogen, the fibrinogen molecules were expelled from the interface upon compression due to the presence of insoluble DPPC molecules.	1,2-Dipalmitoylphosphatidylcholine	24-28	fibrinogen beta chain	Homo sapiens	50-60
16256461-4	2003	For mixed monolayers of DPPC with fibrinogen, the fibrinogen molecules were expelled from the interface upon compression due to the presence of insoluble DPPC molecules.	1,2-Dipalmitoylphosphatidylcholine	154-158	fibrinogen beta chain	Homo sapiens	34-44
16256461-4	2003	For mixed monolayers of DPPC with fibrinogen, the fibrinogen molecules were expelled from the interface upon compression due to the presence of insoluble DPPC molecules.	1,2-Dipalmitoylphosphatidylcholine	154-158	fibrinogen beta chain	Homo sapiens	50-60
16256461-5	2003	The squeeze-out of fibrinogen molecules evidently removed a significant number of DPPC molecules from the interface, with the extent depending on fibrinogen surface concentration.	1,2-Dipalmitoylphosphatidylcholine	82-86	fibrinogen beta chain	Homo sapiens	19-29
16256461-5	2003	The squeeze-out of fibrinogen molecules evidently removed a significant number of DPPC molecules from the interface, with the extent depending on fibrinogen surface concentration.	1,2-Dipalmitoylphosphatidylcholine	82-86	fibrinogen beta chain	Homo sapiens	146-156
16256461-7	2003	The induced loss of free DPPC molecules at the interface by the expelled fibrinogen molecules during the area compression stage was then evaluated from the hysteresis curves.	1,2-Dipalmitoylphosphatidylcholine	25-29	fibrinogen beta chain	Homo sapiens	73-83
12376341-1	2002	The content-dependent activity of surfactant protein (SP)-B was studied in mixtures with dipalmitoyl phosphatidylcholine (DPPC), synthetic lipids (SL), and purified phospholipids (PPL) from calf lung surfactant extract (CLSE).	1,2-Dipalmitoylphosphatidylcholine	122-126	surfactant protein B	Bos taurus	34-59
12225750-2	2002	Two nanosecond long simulations of the N-terminal region of human surfactant protein-B (SP-B(1-25)) in dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylglycerol (DPPG) monolayers of different lipid surface densities reveal the preferential affinity of SP-B(1-25) for anionic phospholipids.	1,2-Dipalmitoylphosphatidylcholine	103-133	surfactant protein B	Homo sapiens	66-86
12225750-2	2002	Two nanosecond long simulations of the N-terminal region of human surfactant protein-B (SP-B(1-25)) in dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylglycerol (DPPG) monolayers of different lipid surface densities reveal the preferential affinity of SP-B(1-25) for anionic phospholipids.	1,2-Dipalmitoylphosphatidylcholine	103-133	surfactant protein B	Homo sapiens	88-92
12225750-2	2002	Two nanosecond long simulations of the N-terminal region of human surfactant protein-B (SP-B(1-25)) in dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylglycerol (DPPG) monolayers of different lipid surface densities reveal the preferential affinity of SP-B(1-25) for anionic phospholipids.	1,2-Dipalmitoylphosphatidylcholine	135-139	surfactant protein B	Homo sapiens	66-86
12225750-2	2002	Two nanosecond long simulations of the N-terminal region of human surfactant protein-B (SP-B(1-25)) in dipalmitoylphosphatidylcholine (DPPC) and dipalmitoylphosphatidylglycerol (DPPG) monolayers of different lipid surface densities reveal the preferential affinity of SP-B(1-25) for anionic phospholipids.	1,2-Dipalmitoylphosphatidylcholine	135-139	surfactant protein B	Homo sapiens	88-92
11951953-2	2002	Differential scanning calorimetry showed that BaP, at concentrations as low as 2 mol% in mixtures with dimyristoylphosphatidylcholine (DMPC), dipalmitoylphosphatidylcholine, and distearoylphosphatidylcholine, abolished the pretransition and broadened and shifted to lower temperatures the main gel-to-liquid crystalline phase transition.	1,2-Dipalmitoylphosphatidylcholine	142-172	prohibitin 2	Homo sapiens	46-49
12458624-9	2002	FBP caused a significant decrease in the FA of DPH in the liquid crystalline state of DPPC (P < 0.05), had no effect on FA of TMA-DPH in the liquid crystalline state of DPPC, but increased the FA of TMA-DPH in the gel state of DPPC.	1,2-Dipalmitoylphosphatidylcholine	86-90	fructose-bisphosphatase 1	Homo sapiens	0-3
11964222-3	2002	P2(1) was further tested in simulations involving the spreading of an octane film on water, and equilibration of a DPPC bilayer from an initial condition containing different numbers of lipids in the two leaflets.	1,2-Dipalmitoylphosphatidylcholine	115-119	cyclin dependent kinase inhibitor 1A	Homo sapiens	0-5
12060563-6	2002	Clearance of [3H]DPPC from the lungs of injured SP-A (-/-) animals was decreased by approximately 40%.	1,2-Dipalmitoylphosphatidylcholine	17-21	surfactant associated protein A1	Mus musculus	48-52
11867456-5	2002	The results show that both the WALP and the KALP peptides tend to favor the liquid-crystalline (or fluid) phase of the system; i.e., they tend to depress the main-transition temperature, T(m), of pure DPPC.	1,2-Dipalmitoylphosphatidylcholine	201-205	anosmin 2, pseudogene	Homo sapiens	44-48
11695915-0	2001	Thermal stability and DPPC/Ca2+ interactions of pulmonary surfactant SP-A from bulk-phase and monolayer IR spectroscopy.	1,2-Dipalmitoylphosphatidylcholine	22-26	surfactant protein A1	Homo sapiens	69-73
16290413-2	2002	A suspension of dipalmitoylphosphatidyl-choline (DPPC) spin-labeled strongly (10%) with a spin probe, 1-palmitoyl-2-(12-doxyl) stearoyl-phosphatidylcholine, was mixed with the surfactant solutions.	1,2-Dipalmitoylphosphatidylcholine	16-47	spindlin 1	Homo sapiens	55-59
16290413-2	2002	A suspension of dipalmitoylphosphatidyl-choline (DPPC) spin-labeled strongly (10%) with a spin probe, 1-palmitoyl-2-(12-doxyl) stearoyl-phosphatidylcholine, was mixed with the surfactant solutions.	1,2-Dipalmitoylphosphatidylcholine	49-53	spindlin 1	Homo sapiens	55-59
16290413-3	2002	The dissolution time of the DPPC membrane was estimated from the peak height change vs time, which was caused by the decrease in spin-exchange interaction.	1,2-Dipalmitoylphosphatidylcholine	28-32	spindlin 1	Homo sapiens	129-133
11718669-0	2001	Phospholipase A(2) activity towards vesicles of DPPC and DMPC-DSPC containing small amounts of SMPC.	1,2-Dipalmitoylphosphatidylcholine	48-52	phospholipase A2 group IB	Homo sapiens	0-18
11718669-2	2001	In this study the activity of PLA(2) towards large unilamellar vesicles composed of DPPC:SMPC and DMPC:DSPC:SMPC is investigated using fluorescence and HPLC techniques.	1,2-Dipalmitoylphosphatidylcholine	84-88	phospholipase A2 group IB	Homo sapiens	30-36
11695915-6	2001	Thermal denaturation of SP-A in the presence of either DPPC or Ca2+ ion reveals a sequence of events involving the initial melting of the collagen-like region, followed by formation of intermolecular extended forms.	1,2-Dipalmitoylphosphatidylcholine	55-59	surfactant protein A1	Homo sapiens	24-28
11695915-7	2001	Interestingly, these spectral changes were inhibited in the ternary system, showing that the combined presence of both DPPC and Ca2+ confers a remarkable thermal stability upon SP-A.	1,2-Dipalmitoylphosphatidylcholine	119-123	surfactant protein A1	Homo sapiens	177-181
11695915-9	2001	The IRRAS measurements indicated that incorporation of SP-A into preformed DPPC monolayers at a surface pressure of 10 mN/m induced a decrease in the average acyl chain tilt angle from 35 degrees to 28 degrees.	1,2-Dipalmitoylphosphatidylcholine	75-79	surfactant protein A1	Homo sapiens	55-59
11687228-5	2001	For complexes with all three apolipoproteins studied, at T<T(t) the probe mobility in the lipid phase of rHDL was significantly higher compared to pure DPPC bilayer.	1,2-Dipalmitoylphosphatidylcholine	155-159	apolipoprotein E	Homo sapiens	29-44
11557027-1	2001	A liposomal Muc1 mucin vaccine for treatment of adenocarcinomas was formulated by incorporating a synthetic Muc1 mucin-based lipopeptide and Lipid A into a DPPC/cholesterol bilayer.	1,2-Dipalmitoylphosphatidylcholine	156-160	mucin 1, transmembrane	Mus musculus	12-16
11557027-7	2001	At 20 mol% cholesterol and with lipopeptide, DSC showed a significant increase in the main phase transition of the DPPC bilayers, while Raman spectroscopy indicated a more ordered arrangement of DPPC molecules compared to control liposomes containing DPPC/cholesterol alone.	1,2-Dipalmitoylphosphatidylcholine	115-119	declival sulcus of cerebellum	Mus musculus	45-48
11292539-6	2001	A significantly higher blood glucose decrease was observed with a DPPC-insulin physical mixture compared to liposome, suggesting a possible effect of the phospholipid chain physical state on the insulin in-vivo absorption.	1,2-Dipalmitoylphosphatidylcholine	66-70	insulin	Homo sapiens	71-78
11523993-4	2001	NAP-22 mixed with dipalmitoylphosphatidylcholine and 40% cholesterol partitions into the detergent insoluble fraction in the presence of 1% Triton X-100.	1,2-Dipalmitoylphosphatidylcholine	18-48	brain abundant membrane attached signal protein 1	Homo sapiens	0-6
11520031-2	2001	The resulting derivative Dans-SP-C conserves the secondary structure of native SP-C as well as the ability to promote interfacial adsorption of DPPC suspensions and to affect the thermotropic behavior of DPPC bilayers.	1,2-Dipalmitoylphosphatidylcholine	144-148	surfactant protein C	Homo sapiens	30-34
11520031-2	2001	The resulting derivative Dans-SP-C conserves the secondary structure of native SP-C as well as the ability to promote interfacial adsorption of DPPC suspensions and to affect the thermotropic behavior of DPPC bilayers.	1,2-Dipalmitoylphosphatidylcholine	204-208	surfactant protein C	Homo sapiens	30-34
11305923-6	2001	The labeled apoA-I was reconstituted into well-defined HDL complexes containing two molecules of protein and dipalmitoylphosphatidylcholine, and the complexes were used in three quantitative fluorescence resonance energy transfer (FRET) experiments to determine the distances between two specific sites in an HDL particle.	1,2-Dipalmitoylphosphatidylcholine	109-139	apolipoprotein A1	Homo sapiens	12-18
11565844-0	2001	Substance P (free acid) adopts different conformation than native peptide in DMSO, water and DPPC bilayers.	1,2-Dipalmitoylphosphatidylcholine	93-97	tachykinin precursor 1	Homo sapiens	0-11
11565844-1	2001	The conformation of substance P (free acid) (SPOH) has been investigated in dimethylsulfoxide (DMSO), water and dipalmitoylphosphotidylcholine (DPPC) bilayers by two-dimensional NMR and restraint molecular dynamics simulations.	1,2-Dipalmitoylphosphatidylcholine	144-148	tachykinin precursor 1	Homo sapiens	20-31
11425766-8	2001	Mice receiving recombinant apoA-I(m) had 40% to 50% lower lipid content (P<0.01) and 29% to 36% lower macrophage content (P<0.05) in their plaques compared with the saline- and DPPC-treated mice, respectively.	1,2-Dipalmitoylphosphatidylcholine	183-187	apolipoprotein A-I	Mus musculus	27-33
11292539-6	2001	A significantly higher blood glucose decrease was observed with a DPPC-insulin physical mixture compared to liposome, suggesting a possible effect of the phospholipid chain physical state on the insulin in-vivo absorption.	1,2-Dipalmitoylphosphatidylcholine	66-70	insulin	Homo sapiens	195-202
11238016-1	2001	This study evaluated the role of a lysosomal-type phospholipase A2 (aiPLA(2)) in the degradation of internalized dipalmitoylphosphatidylcholine (DPPC) and in phospholipid synthesis by the rat lung.	1,2-Dipalmitoylphosphatidylcholine	113-143	peroxiredoxin 6	Rattus norvegicus	68-76
11332933-5	2001	Therefore, the presence of PLA2 activity in meconium, collected from 10 newborns, was measured by the formation of lysophosphatidylcholine after incubation of meconium with radioactively labelled dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	196-226	phospholipase A2 group IB	Homo sapiens	27-31
11238016-1	2001	This study evaluated the role of a lysosomal-type phospholipase A2 (aiPLA(2)) in the degradation of internalized dipalmitoylphosphatidylcholine (DPPC) and in phospholipid synthesis by the rat lung.	1,2-Dipalmitoylphosphatidylcholine	145-149	peroxiredoxin 6	Rattus norvegicus	68-76
11238016-9	2001	These results obtained with intact rat lungs indicate that aiPLA(2) is a major enzyme for degradation of internalized DPPC and also has an important role in DPPC synthesis.	1,2-Dipalmitoylphosphatidylcholine	118-122	peroxiredoxin 6	Rattus norvegicus	59-67
11238016-9	2001	These results obtained with intact rat lungs indicate that aiPLA(2) is a major enzyme for degradation of internalized DPPC and also has an important role in DPPC synthesis.	1,2-Dipalmitoylphosphatidylcholine	157-161	peroxiredoxin 6	Rattus norvegicus	59-67
11359446-7	2001	We also demonstrated that total PC (tPC; a heterogeneous species of PC from egg) and DPPC but not PAPC significantly inhibited the release of TNF-alpha from MM6 cells (P < 0.05).	1,2-Dipalmitoylphosphatidylcholine	85-89	tumor necrosis factor	Homo sapiens	142-151
11159019-1	2001	Metabolism of surfactant protein (SP) A and dipalmitoylphosphatidylcholine (DPPC) was assessed in alveolar macrophages isolated from granulocyte-macrophage colony-stimulated factor (GM-CSF) gene-targeted [GM(-/-)] mice, wild-type mice, and GM(-/-) mice expressing GM-CSF under control of the SP-C promoter element (SP-C-GM).	1,2-Dipalmitoylphosphatidylcholine	44-74	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	182-188
11159019-1	2001	Metabolism of surfactant protein (SP) A and dipalmitoylphosphatidylcholine (DPPC) was assessed in alveolar macrophages isolated from granulocyte-macrophage colony-stimulated factor (GM-CSF) gene-targeted [GM(-/-)] mice, wild-type mice, and GM(-/-) mice expressing GM-CSF under control of the SP-C promoter element (SP-C-GM).	1,2-Dipalmitoylphosphatidylcholine	76-80	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	133-180
11282244-9	2001	In conclusion, this study suggest that degradation of the lipid bilayer of PEG-liposomes by PLA(2) result in release of incapsulated drug, e.g. gentamicin and inclusion of PE in the liposomal bilayer, may enhance the activity of the mammalian sPLA(2) toward liposomes composed of DPPC.	1,2-Dipalmitoylphosphatidylcholine	280-284	phospholipase A2 group IB	Homo sapiens	92-98
11245834-4	2001	Higher activity in DPPC refinement of the monolayer was observed for SP-B compared with SP-C.	1,2-Dipalmitoylphosphatidylcholine	19-23	surfactant protein B	Homo sapiens	69-73
11245834-4	2001	Higher activity in DPPC refinement of the monolayer was observed for SP-B compared with SP-C.	1,2-Dipalmitoylphosphatidylcholine	19-23	surfactant protein C	Homo sapiens	88-92
11106621-5	2000	Addition of surfactant protein B (SP-B) to the surface film led to a progressive decrease in minimum surface tension toward 1 mN/m upon cycling, indicating an enrichment in DPPC.	1,2-Dipalmitoylphosphatidylcholine	173-177	surfactant protein B	Homo sapiens	12-32
11329264-9	2001	The second phase was absent when IFABP interacted with zwitterionic monolayers of 1,2-dipalmitoylphosphatidylcholine, revealing the important role of electrostatics at this stage.	1,2-Dipalmitoylphosphatidylcholine	82-116	fatty acid binding protein 2	Homo sapiens	33-38
11160365-7	2001	The DPPC emulsions bound more apoB-17 than EYPC or DMPC emulsions.	1,2-Dipalmitoylphosphatidylcholine	4-8	apolipoprotein B	Homo sapiens	30-34
11160365-8	2001	Immunoaffinity-purified apoB-17 exhibited saturable, high affinity binding to EYPC and DPPC emulsions.	1,2-Dipalmitoylphosphatidylcholine	87-91	apolipoprotein B	Homo sapiens	24-28
11152270-2	2000	The decrease in the intensity of the nuC=O ester band of dipalmitoylphosphatidylcholine at 1733 cm(-1) and the appearance of two new infrared bands in the 1530-1580 cm(-1) region allowed to monitor phospholipid hydrolysis by PLA2.	1,2-Dipalmitoylphosphatidylcholine	57-87	nucleobindin 1	Homo sapiens	37-40
11106621-5	2000	Addition of surfactant protein B (SP-B) to the surface film led to a progressive decrease in minimum surface tension toward 1 mN/m upon cycling, indicating an enrichment in DPPC.	1,2-Dipalmitoylphosphatidylcholine	173-177	surfactant protein B	Homo sapiens	34-38
11106621-10	2000	SP-A, combined with SP-B, induces a selective adsorption of DPPC from subphase vesicles into the surface film.	1,2-Dipalmitoylphosphatidylcholine	60-64	surfactant protein A1	Homo sapiens	0-4
11106621-10	2000	SP-A, combined with SP-B, induces a selective adsorption of DPPC from subphase vesicles into the surface film.	1,2-Dipalmitoylphosphatidylcholine	60-64	surfactant protein B	Homo sapiens	20-24
12567917-0	2000	[Interactions of insulin with dipalmitoylphosphatidylcholine liposomes].	1,2-Dipalmitoylphosphatidylcholine	30-60	insulin	Homo sapiens	17-24
12567917-1	2000	AIM: To study the interactions of insulin with dipalmitoylphosphatidylcholine liposomes.	1,2-Dipalmitoylphosphatidylcholine	47-77	insulin	Homo sapiens	34-41
12567917-6	2000	The insertion of tyrosine of insulin into dipalmitoylphosphatidylcholine liposomes membrane was not deep.	1,2-Dipalmitoylphosphatidylcholine	42-72	insulin	Homo sapiens	29-36
11029372-13	2000	In the presence of SP-B/C, surface activity corresponds to the concentration of DPPC.	1,2-Dipalmitoylphosphatidylcholine	80-84	surfactant protein B	Bos taurus	19-23
11053136-1	2000	Bovine rhodopsin was reconstituted into mixtures of didocosahexaenoylphosphatidylcholine (di22:6-PC), dipalmitoylphosphatidylcholine (di16:0-PC), sn-1-palmitoyl-sn-2-docosahexaenoylphosphatidylcholine (16:0, 22:6-PC) and cholesterol.	1,2-Dipalmitoylphosphatidylcholine	102-132	rhodopsin	Bos taurus	7-16
10946014-5	2000	At this concentration of apoA-I, POPC rHDL inhibited by only 16% and DPPC rHDL did not inhibit at all.	1,2-Dipalmitoylphosphatidylcholine	69-73	apolipoprotein A1	Homo sapiens	25-31
11030586-10	2000	We describe a model proposing that SP-A and SP-B create DPPC enriched domains which can readily be adsorbed to create a DPPC-rich monolayer at the interface.	1,2-Dipalmitoylphosphatidylcholine	56-60	surfactant protein A1	Homo sapiens	35-39
11030586-10	2000	We describe a model proposing that SP-A and SP-B create DPPC enriched domains which can readily be adsorbed to create a DPPC-rich monolayer at the interface.	1,2-Dipalmitoylphosphatidylcholine	56-60	surfactant protein B	Homo sapiens	44-48
11030586-10	2000	We describe a model proposing that SP-A and SP-B create DPPC enriched domains which can readily be adsorbed to create a DPPC-rich monolayer at the interface.	1,2-Dipalmitoylphosphatidylcholine	120-124	surfactant protein A1	Homo sapiens	35-39
11030586-10	2000	We describe a model proposing that SP-A and SP-B create DPPC enriched domains which can readily be adsorbed to create a DPPC-rich monolayer at the interface.	1,2-Dipalmitoylphosphatidylcholine	120-124	surfactant protein B	Homo sapiens	44-48
10964416-6	2000	Catalytically, DAGK showed a strong preference for bicelles containing 3-(cholamidopropyl)dimethylammonio-2-hydroxy-1-propanesulfonate (CHAPSO) as the detergentcomponent relative to short-chained phosphatidylcholine.DAGK also exhibited a preference for dimyristoylphosphatidylcholine or dipalmitoylphosphatidylcholine bicelles relative to those of dilauroylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	287-317	diacylglycerol kinase alpha	Homo sapiens	15-19
11028030-0	2000	Dynamic Observations of the Hydrolysis of a DPPC Monolayer at the Air/Water Interface Catalyzed by Phospholipase A(2) This work was supported by the research contract between the German Max-Planck-Society and the Chinese Academy of Sciences as well as the National Natural Science Foundation of China (NNSF).	1,2-Dipalmitoylphosphatidylcholine	44-48	phospholipase A2 group IB	Homo sapiens	99-116
11001826-3	2000	SP-A and SP-D are large hydrophilic proteins, which play an important role in host defense, whereas the small hydrophobic peptides SP-B and SP-C interact with DPPC to generate and maintain a surface-active film.	1,2-Dipalmitoylphosphatidylcholine	159-163	surfactant protein A1	Homo sapiens	0-4
11001826-3	2000	SP-A and SP-D are large hydrophilic proteins, which play an important role in host defense, whereas the small hydrophobic peptides SP-B and SP-C interact with DPPC to generate and maintain a surface-active film.	1,2-Dipalmitoylphosphatidylcholine	159-163	surfactant protein B	Homo sapiens	131-135
11001826-3	2000	SP-A and SP-D are large hydrophilic proteins, which play an important role in host defense, whereas the small hydrophobic peptides SP-B and SP-C interact with DPPC to generate and maintain a surface-active film.	1,2-Dipalmitoylphosphatidylcholine	159-163	surfactant protein C	Homo sapiens	140-144
10924113-5	2000	All apoC-III proteins bound to the apoE:DPPC complexes; the amount of apoE displaced from the complex was dependent on the apoC-III lipid binding affinity.	1,2-Dipalmitoylphosphatidylcholine	40-44	apolipoprotein C3	Homo sapiens	4-12
10924113-5	2000	All apoC-III proteins bound to the apoE:DPPC complexes; the amount of apoE displaced from the complex was dependent on the apoC-III lipid binding affinity.	1,2-Dipalmitoylphosphatidylcholine	40-44	apolipoprotein E	Homo sapiens	35-39
10924113-5	2000	All apoC-III proteins bound to the apoE:DPPC complexes; the amount of apoE displaced from the complex was dependent on the apoC-III lipid binding affinity.	1,2-Dipalmitoylphosphatidylcholine	40-44	apolipoprotein E	Homo sapiens	70-74
10880156-5	2000	There was a direct correlation between fluorescence and residual phospholipid surfactant remaining on particles using phospholipase A2 (PLA(2)) digestion in a cell-free system, indicating that the presence of the fluorophore on DPPC did not hinder enzymatic recognition.	1,2-Dipalmitoylphosphatidylcholine	228-232	phospholipase A2 group IB	Rattus norvegicus	118-134
10880156-5	2000	There was a direct correlation between fluorescence and residual phospholipid surfactant remaining on particles using phospholipase A2 (PLA(2)) digestion in a cell-free system, indicating that the presence of the fluorophore on DPPC did not hinder enzymatic recognition.	1,2-Dipalmitoylphosphatidylcholine	228-232	phospholipase A2 group IB	Rattus norvegicus	136-142
10866961-7	2000	The ternary mixture DPPC/DPPG/SP-C transferred from the collapse region exhibited SP-C-rich domains surrounding pure lipid areas.	1,2-Dipalmitoylphosphatidylcholine	20-24	surfactant protein C	Homo sapiens	30-34
10866961-7	2000	The ternary mixture DPPC/DPPG/SP-C transferred from the collapse region exhibited SP-C-rich domains surrounding pure lipid areas.	1,2-Dipalmitoylphosphatidylcholine	20-24	surfactant protein C	Homo sapiens	82-86
10918482-4	2000	Egg yolk phosphatidylcholine- and dipalmitoylphosphatidylcholine-based PCL were as effective as dioleoylphosphatidylethanolamine-based PCLs for gene transfer.	1,2-Dipalmitoylphosphatidylcholine	34-64	polycystic kidney disease 2-like 1	Mus musculus	71-74
10750736-1	2000	Dipalmitoyl phosphatidylcholine (DPPC) is a major phospholipid constituent in the pulmonary surfactant, whereas lysophosphatidylcholine (Lyso-PC) is a minor constituent, this membrane phospholipid being produced at inflammatory sites in association with activation of phospholipase A2.	1,2-Dipalmitoylphosphatidylcholine	0-31	phospholipase A2	Oryctolagus cuniculus	268-284
10793226-5	2000	Unlike VIP, injection of [(8)Arg]-vasopressin at an equimolar concentration only prevented the time-dependent decline in DPPC monolayer surface pressure.	1,2-Dipalmitoylphosphatidylcholine	121-125	arginine vasopressin	Homo sapiens	34-45
10645886-6	2000	[(3)H]choline was released when natural surfactant containing [(3)H]choline-labeled DPPC was cycled with yeast phospholipase D but not with convertase or peanut and cabbage phospholipases D. Similarly, yeast phospholipase D hydrolyzed [(3)H]choline from [(3)H]choline-labeled DPPC after incubation in vitro, whereas convertase, liver esterase, or peanut and cabbage phospholipases D did not.	1,2-Dipalmitoylphosphatidylcholine	84-88	phospholipase D	Saccharomyces cerevisiae S288C	111-126
10828943-3	2000	Recombinant rat SP-A, containing a deletion of the collagen-like domain, was incubated with dipalmitoylphosphatidylcholine:egg phosphatidylcholine (1:1, wt/wt) lipid monolayers in the presence of calcium, negatively stained, and examined by transmission electron microscopy.	1,2-Dipalmitoylphosphatidylcholine	92-122	surfactant protein A1	Rattus norvegicus	16-20
10821681-4	2000	Surfactant proteins, SP-B or SP-C, when present in the films of DPPC:PG spread at pi(i) = 5 mN/m, enhanced the incorporation of SP-A in the monolayers to a similar extent; the Deltapi values being dependent on the levels of SP-B or SP-C, 3-17 wt %, in the lipid films.	1,2-Dipalmitoylphosphatidylcholine	64-68	surfactant protein B	Homo sapiens	21-25
10821681-4	2000	Surfactant proteins, SP-B or SP-C, when present in the films of DPPC:PG spread at pi(i) = 5 mN/m, enhanced the incorporation of SP-A in the monolayers to a similar extent; the Deltapi values being dependent on the levels of SP-B or SP-C, 3-17 wt %, in the lipid films.	1,2-Dipalmitoylphosphatidylcholine	64-68	surfactant protein C	Homo sapiens	29-33
10821681-7	2000	Values of Deltapi produced by adsorption of SP-A to the films of DPPC:PG with or without SP-B or SP-C were a function of the initial surface pressure of the films, pi(i).	1,2-Dipalmitoylphosphatidylcholine	65-69	surfactant protein A2	Homo sapiens	44-48
10821681-9	2000	Monolayers of DPPC:PG plus 17 wt % SP-B or SP-C, which had similar phase properties with LC phase occupying a maximum 25% of the total monolayer area, displayed different abilities to enhance the adsorption of SP-A to the surface.	1,2-Dipalmitoylphosphatidylcholine	14-18	surfactant protein B	Homo sapiens	35-39
10821681-9	2000	Monolayers of DPPC:PG plus 17 wt % SP-B or SP-C, which had similar phase properties with LC phase occupying a maximum 25% of the total monolayer area, displayed different abilities to enhance the adsorption of SP-A to the surface.	1,2-Dipalmitoylphosphatidylcholine	14-18	surfactant protein C	Homo sapiens	43-47
10821681-9	2000	Monolayers of DPPC:PG plus 17 wt % SP-B or SP-C, which had similar phase properties with LC phase occupying a maximum 25% of the total monolayer area, displayed different abilities to enhance the adsorption of SP-A to the surface.	1,2-Dipalmitoylphosphatidylcholine	14-18	surfactant protein A2	Homo sapiens	210-214
10653651-2	2000	SP-A binds dipalmitoylphosphatidylcholine (DPPC) and galactosylceramide (GalCer), induces liposome aggregation, and regulates the uptake and secretion of surfactant lipids by alveolar type II cells in vitro.	1,2-Dipalmitoylphosphatidylcholine	11-41	surfactant protein A1	Rattus norvegicus	0-4
10653651-2	2000	SP-A binds dipalmitoylphosphatidylcholine (DPPC) and galactosylceramide (GalCer), induces liposome aggregation, and regulates the uptake and secretion of surfactant lipids by alveolar type II cells in vitro.	1,2-Dipalmitoylphosphatidylcholine	43-47	surfactant protein A1	Rattus norvegicus	0-4
10651816-2	2000	Light scattering was used to monitor Rz1-induced aggregation of artificial neutral (dipalmitoylphosphatidylcholine/cholesterol) and negatively charged (dipalmitoylphosphatidylcholine/cholesterol/dioleoylphosphatidylserin e) liposomes.	1,2-Dipalmitoylphosphatidylcholine	84-114	prolysis lipoprotein RzoD	Escherichia virus Lambda	37-40
10651816-2	2000	Light scattering was used to monitor Rz1-induced aggregation of artificial neutral (dipalmitoylphosphatidylcholine/cholesterol) and negatively charged (dipalmitoylphosphatidylcholine/cholesterol/dioleoylphosphatidylserin e) liposomes.	1,2-Dipalmitoylphosphatidylcholine	152-182	prolysis lipoprotein RzoD	Escherichia virus Lambda	37-40
10590028-6	1999	SP-B (+/-) mice were administered purified bovine SP-B (2%) with DL-alpha dipalmitoyl phosphatidylcholine (DPPC) and 1-palmitoyl-2-oleoyl-sn-glycero-3-[phospho-rac-( -glycerol)] (POPG) phospholipids or DPPC and POPG phospholipids intratracheally and exposed to 95% oxygen.	1,2-Dipalmitoylphosphatidylcholine	107-111	surfactant protein B	Bos taurus	50-54
10590028-9	1999	Abnormalities in pulmonary function in SP-B (+/-) mice after oxygen exposure were associated with increased alveolar capillary leak, which was corrected by administration of SP-B with DPPC and POPG.	1,2-Dipalmitoylphosphatidylcholine	184-188	surfactant associated protein B	Mus musculus	39-43
10590028-9	1999	Abnormalities in pulmonary function in SP-B (+/-) mice after oxygen exposure were associated with increased alveolar capillary leak, which was corrected by administration of SP-B with DPPC and POPG.	1,2-Dipalmitoylphosphatidylcholine	184-188	surfactant associated protein B	Mus musculus	174-178
10590028-10	1999	Likewise, histologic abnormalities caused by oxygen-induced lung injury were improved by administration of SP-B with DPPC and POPG.	1,2-Dipalmitoylphosphatidylcholine	117-121	surfactant associated protein B	Mus musculus	107-111
10100608-0	1999	Stoichiometry of dipalmitoylphosphatidylcholine-DNA interaction in the presence of Ca2+: a temperature-scanning ultrasonic study.	1,2-Dipalmitoylphosphatidylcholine	17-47	carbonic anhydrase 2	Homo sapiens	83-86
10446309-0	1999	Lag-burst kinetics in phospholipase A(2) hydrolysis of DPPC bilayers visualized by atomic force microscopy.	1,2-Dipalmitoylphosphatidylcholine	55-59	stathmin 1	Homo sapiens	0-3
10543393-8	1999	During incubations for 10 min and 360 min, normal apoA-I/DPPC complexes and apoA-I(R151C)Paris/DPPC complexes were equally efficient in releasing biosynthetic cholesterol from SMCs.	1,2-Dipalmitoylphosphatidylcholine	95-99	apolipoprotein A-I	Mus musculus	76-82
10233065-1	1999	The conventional formula for relating CD2 average order parameters <Sn> to average methylenic travel <Dn> is flawed when compared to molecular dynamics simulations of dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	179-209	CD2 molecule	Homo sapiens	38-41
10224161-0	1999	Interactions of pulmonary surfactant protein SP-A with monolayers of dipalmitoylphosphatidylcholine and cholesterol: roles of SP-A domains.	1,2-Dipalmitoylphosphatidylcholine	69-99	surfactant protein A1	Rattus norvegicus	45-49
10224161-1	1999	Pulmonary surfactant protein A (SP-A) is an oligomeric glycoprotein that binds dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	79-109	surfactant protein A1	Rattus norvegicus	32-36
10224161-1	1999	Pulmonary surfactant protein A (SP-A) is an oligomeric glycoprotein that binds dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	111-115	surfactant protein A1	Rattus norvegicus	32-36
10224161-2	1999	Interactions of rat SP-A and recombinant SP-As with pure and binary monolayers of DPPC and cholesterol were studied using a rhomboid surface balance at 37 degrees C. A marked inflection at equilibrium surface tension (23 mN/m) in surface tension-area isotherm of a pure DPPC film was abolished by rat SP-A.	1,2-Dipalmitoylphosphatidylcholine	82-86	surfactant protein A1	Rattus norvegicus	41-45
10224161-4	1999	Both rat SP-A and SP-Ahyp decreased surface area reduction required for pure DPPC films to reach near zero surface tension from 30 to 25%.	1,2-Dipalmitoylphosphatidylcholine	77-81	surfactant protein A1	Rattus norvegicus	9-13
10224161-4	1999	Both rat SP-A and SP-Ahyp decreased surface area reduction required for pure DPPC films to reach near zero surface tension from 30 to 25%.	1,2-Dipalmitoylphosphatidylcholine	77-81	surfactant protein A1	Rattus norvegicus	18-25
10224161-5	1999	SP-Ahyp, E195Q,R197D, mutated in carbohydrate recognition domain (CRD) known to be essential for SP-A-vesicle interactions, conveyed a detrimental effect on DPPC surface activity.	1,2-Dipalmitoylphosphatidylcholine	157-161	surfactant protein A1	Rattus norvegicus	0-7
10224161-5	1999	SP-Ahyp, E195Q,R197D, mutated in carbohydrate recognition domain (CRD) known to be essential for SP-A-vesicle interactions, conveyed a detrimental effect on DPPC surface activity.	1,2-Dipalmitoylphosphatidylcholine	157-161	surfactant protein A1	Rattus norvegicus	0-4
10224161-9	1999	When mixed films were formed by successive spreading of DPPC/SP-A/cholesterol, rat SP-A, SP-Ahyp, or SP-ADeltaG8-P80 blocked the interaction of cholesterol with DPPC; SP-Ahyp,E195Q,R197D could not impede the interaction; SP-Ahyp,C6S or SP-Ahyp,DeltaN1-A7 only partially blocked the interaction, and cholesterol appeared to stabilize SP-Ahyp,C6S-DPPC association.	1,2-Dipalmitoylphosphatidylcholine	56-60	surfactant protein A1	Rattus norvegicus	83-87
10224161-9	1999	When mixed films were formed by successive spreading of DPPC/SP-A/cholesterol, rat SP-A, SP-Ahyp, or SP-ADeltaG8-P80 blocked the interaction of cholesterol with DPPC; SP-Ahyp,E195Q,R197D could not impede the interaction; SP-Ahyp,C6S or SP-Ahyp,DeltaN1-A7 only partially blocked the interaction, and cholesterol appeared to stabilize SP-Ahyp,C6S-DPPC association.	1,2-Dipalmitoylphosphatidylcholine	161-165	surfactant protein A1	Rattus norvegicus	83-87
10224161-9	1999	When mixed films were formed by successive spreading of DPPC/SP-A/cholesterol, rat SP-A, SP-Ahyp, or SP-ADeltaG8-P80 blocked the interaction of cholesterol with DPPC; SP-Ahyp,E195Q,R197D could not impede the interaction; SP-Ahyp,C6S or SP-Ahyp,DeltaN1-A7 only partially blocked the interaction, and cholesterol appeared to stabilize SP-Ahyp,C6S-DPPC association.	1,2-Dipalmitoylphosphatidylcholine	161-165	surfactant protein A1	Rattus norvegicus	89-96
10535954-0	1999	Self-assembly of fibronectin into fibrillar networks underneath dipalmitoyl phosphatidylcholine monolayers: role of lipid matrix and tensile forces.	1,2-Dipalmitoylphosphatidylcholine	64-95	fibronectin 1	Homo sapiens	17-28
10535954-2	1999	We have identified conditions under which Fn assembles into extended fibrillar networks after adsorption to a dipalmitoyl phosphatidylcholine (DPPC) monolayer in contact with physiological buffer.	1,2-Dipalmitoylphosphatidylcholine	110-141	fibronectin 1	Homo sapiens	42-44
10535954-2	1999	We have identified conditions under which Fn assembles into extended fibrillar networks after adsorption to a dipalmitoyl phosphatidylcholine (DPPC) monolayer in contact with physiological buffer.	1,2-Dipalmitoylphosphatidylcholine	143-147	fibronectin 1	Homo sapiens	42-44
10535954-3	1999	We propose a sequential model for the Fn assembly pathway, which involves the orientation of Fn underneath the lipid monolayer by insertion into the liquid expanded (LE) phase of DPPC.	1,2-Dipalmitoylphosphatidylcholine	179-183	fibronectin 1	Homo sapiens	38-40
10526225-4	1999	K(d)=5 microM is obtained for the complex between SP-A and dipalmitoylphosphatidylcholine (DPPC) liposomes.	1,2-Dipalmitoylphosphatidylcholine	59-89	surfactant protein A1	Homo sapiens	50-54
10526225-4	1999	K(d)=5 microM is obtained for the complex between SP-A and dipalmitoylphosphatidylcholine (DPPC) liposomes.	1,2-Dipalmitoylphosphatidylcholine	91-95	surfactant protein A1	Homo sapiens	50-54
10526225-6	1999	With palmitoyloleoylphosphatidylcholine (POPC), the complex formation proceeds at half the rate, compared to DPPC, leading to a lower final equilibrium level of SP-A lipid interaction.	1,2-Dipalmitoylphosphatidylcholine	109-113	surfactant protein A1	Homo sapiens	161-165
10529890-6	1999	The administration of insulin contained in DPPC/SG (7/4, mole) liposomes with high fluidity caused a high glucose reduction of long duration (8 hr).	1,2-Dipalmitoylphosphatidylcholine	43-47	insulin	Oryctolagus cuniculus	22-29
10561470-5	1999	Non-specific binding of bovine serum albumin was found to be very low when DPPC was used as the host matrix.	1,2-Dipalmitoylphosphatidylcholine	75-79	albumin	Homo sapiens	31-44
10561470-8	1999	The results demonstrate that the covalent coupling of Fab" fragments to N-(epsilon-maleimidocaproyl)-dipalmitoylphosphatidylethanolamine (DPPE-EMC) embedded in a host monolayer matrix of DPPC is a promising approach to achieve a site-directed immobilisation of antibodies with high antigen-binding efficiency.	1,2-Dipalmitoylphosphatidylcholine	187-191	FA complementation group B	Homo sapiens	54-57
10465757-2	1999	At pH 7.4, TR-SP-A expanded the pi-A isotherms of film of dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	58-88	surfactant protein A1	Homo sapiens	14-18
10465757-2	1999	At pH 7.4, TR-SP-A expanded the pi-A isotherms of film of dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	90-94	surfactant protein A1	Homo sapiens	14-18
10465757-4	1999	At pH 4.5, TR-SP-A expanded DPPC monolayers to a slightly lower extent than at pH 7.4.	1,2-Dipalmitoylphosphatidylcholine	28-32	surfactant protein A1	Homo sapiens	14-18
10465757-6	1999	Films of DPPC/dipalmitoylphosphatidylglycerol (DPPG) 7:3 mol/mol were somewhat expanded by TR-SP-A at pH 7.4.	1,2-Dipalmitoylphosphatidylcholine	9-13	surfactant protein A1	Homo sapiens	94-98
10361145-3	1999	In this study, the blood clearance and the PLA2 catalyzed degradation of unilamellar dipalmitoylphosphatidylcholine (DPPC) liposomes incorporated with increasing amounts of dipalmitoylphosphatidylethanolamine-polyethyleneglycol (DPPE-PEG), was investigated.	1,2-Dipalmitoylphosphatidylcholine	85-115	phospholipase A2 group IB	Homo sapiens	43-47
10361145-3	1999	In this study, the blood clearance and the PLA2 catalyzed degradation of unilamellar dipalmitoylphosphatidylcholine (DPPC) liposomes incorporated with increasing amounts of dipalmitoylphosphatidylethanolamine-polyethyleneglycol (DPPE-PEG), was investigated.	1,2-Dipalmitoylphosphatidylcholine	117-121	phospholipase A2 group IB	Homo sapiens	43-47
10361147-4	1999	The temperature dependence of the PLA2 lag-time, denoting the time required before a sudden increase in enzymatic activity takes place, has been determined for submicellar amounts of dipalmitoylphosphatidylethanolaminyl-poly-(ethylene glycol) (DPPE-PEG2000) incorporated into unilamellar dipalmitoylphosphatidylcholine (DPPC)-liposomes.	1,2-Dipalmitoylphosphatidylcholine	288-318	phospholipase A2 group IB	Homo sapiens	34-38
10361147-4	1999	The temperature dependence of the PLA2 lag-time, denoting the time required before a sudden increase in enzymatic activity takes place, has been determined for submicellar amounts of dipalmitoylphosphatidylethanolaminyl-poly-(ethylene glycol) (DPPE-PEG2000) incorporated into unilamellar dipalmitoylphosphatidylcholine (DPPC)-liposomes.	1,2-Dipalmitoylphosphatidylcholine	320-324	phospholipase A2 group IB	Homo sapiens	34-38
10353843-3	1999	SP-A binds to dipalmitoyl phosphatidylcholine (DPPC) and galactosylceramide (GalCer) and MBP-A binds to phosphatidylinositol (PI).	1,2-Dipalmitoylphosphatidylcholine	14-45	surfactant protein A1	Homo sapiens	0-4
10353843-3	1999	SP-A binds to dipalmitoyl phosphatidylcholine (DPPC) and galactosylceramide (GalCer) and MBP-A binds to phosphatidylinositol (PI).	1,2-Dipalmitoylphosphatidylcholine	47-51	surfactant protein A1	Homo sapiens	0-4
10198360-6	1999	Coincubation with two different commercially available surfactants but not with dipalmitoylphosphatidylcholine alone resulted in a reduction of fibronectin incorporation into fibrin clots by approximately one-third.	1,2-Dipalmitoylphosphatidylcholine	80-110	fibronectin 1	Homo sapiens	144-155
10064737-3	1999	During cholate dialysis, normal apoA-I and both variants associated completely with dipalmitoylphosphatidylcholine (DPPC) and formed rLpA-I of identical size.	1,2-Dipalmitoylphosphatidylcholine	84-114	apolipoprotein A-I	Mus musculus	32-38
10064737-3	1999	During cholate dialysis, normal apoA-I and both variants associated completely with dipalmitoylphosphatidylcholine (DPPC) and formed rLpA-I of identical size.	1,2-Dipalmitoylphosphatidylcholine	116-120	apolipoprotein A-I	Mus musculus	32-38
10064737-6	1999	ApoA-I/DPPC complexes induced biphasic cholesterol efflux from SMCs with a fast and a slow efflux component.	1,2-Dipalmitoylphosphatidylcholine	7-11	apolipoprotein A-I	Mus musculus	0-6
9929491-6	1999	This was demonstrated with 1, 2-palmitoyl-sn-glycero-3-phosphocholine (DPPC) liposomes incorporating PPDPG (XPPDPG = 0.03), i.e., conditions where XPG in fluid bilayers is below the required threshold yielding the fast component.	1,2-Dipalmitoylphosphatidylcholine	71-75	ERCC excision repair 5, endonuclease	Homo sapiens	147-150
9833996-2	1998	METHODS: AmB was encapsulated in dipalmitoylphosphatidylcholine/ cholesterol (DPPC/CH, 2:1) liposomes after complex formation with distearoyl-N-(monomethoxy poly(ethylene glycol)succinyl) phosphatidylethanolamine (DSPE-PEG).	1,2-Dipalmitoylphosphatidylcholine	33-63	SUN domain containing ossification factor	Homo sapiens	78-90
9889301-2	1999	Surface thermodynamic properties, secondary structure, and orientation of native and deacylated SP-C in 1, 2-dipalmitoylphosphatidylcholine (DPPC) monolayers has been characterized by combined surface pressure-molecular area (pi-A) isotherms and infrared reflection-absorption spectroscopy (IRRAS) measurements.	1,2-Dipalmitoylphosphatidylcholine	104-139	surfactant protein C	Homo sapiens	96-100
9889301-2	1999	Surface thermodynamic properties, secondary structure, and orientation of native and deacylated SP-C in 1, 2-dipalmitoylphosphatidylcholine (DPPC) monolayers has been characterized by combined surface pressure-molecular area (pi-A) isotherms and infrared reflection-absorption spectroscopy (IRRAS) measurements.	1,2-Dipalmitoylphosphatidylcholine	141-145	surfactant protein C	Homo sapiens	96-100
9858708-0	1998	Rotational dynamics of spin-labelled surfactant-associated proteins SP-B and SP-C in dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylglycerol bilayers.	1,2-Dipalmitoylphosphatidylcholine	85-115	surfactant protein B	Homo sapiens	68-72
9858708-0	1998	Rotational dynamics of spin-labelled surfactant-associated proteins SP-B and SP-C in dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylglycerol bilayers.	1,2-Dipalmitoylphosphatidylcholine	85-115	surfactant protein C	Homo sapiens	77-81
9630660-2	1998	SP-B binding to membranes was studied by labeling the protein with the fluorophore 7-nitro-2,1,3-benzoxadiazol-4-yl (NBD) and measuring the fluorescence of the labeled protein in the presence of varying amounts of dipalmitoylphosphatidylcholine-egg phosphatidylglycerol (DPPC-eggPG; 7-3).	1,2-Dipalmitoylphosphatidylcholine	214-244	surfactant protein B	Homo sapiens	0-4
9735345-2	1998	On phosphatidylcholine or especially dipalmitoylphosphatidylcholine monolayers, SP-A at roughly 0.005 mg/ml formed large numbers of fibers and elaborate fibrous networks.	1,2-Dipalmitoylphosphatidylcholine	37-67	pulmonary surfactant-associated protein A	Bos taurus	80-84
9733909-1	1998	Phospholipase A2 (PLA2)-catalyzed hydrolysis of dipalmitoylphosphatidylcholine (DPPC) liposomes incorporated with submicellar concentrations of polyethyleneoxide covalently attached to dipalmitoylphosphatidylethanolamine (DPPE-PEG2000) has been studied in the gel-to-fluid transition region of the host DPPC lipid bilayer matrix.	1,2-Dipalmitoylphosphatidylcholine	48-78	phospholipase A2 group IB	Homo sapiens	0-16
9733909-1	1998	Phospholipase A2 (PLA2)-catalyzed hydrolysis of dipalmitoylphosphatidylcholine (DPPC) liposomes incorporated with submicellar concentrations of polyethyleneoxide covalently attached to dipalmitoylphosphatidylethanolamine (DPPE-PEG2000) has been studied in the gel-to-fluid transition region of the host DPPC lipid bilayer matrix.	1,2-Dipalmitoylphosphatidylcholine	48-78	phospholipase A2 group IB	Homo sapiens	18-22
9733909-1	1998	Phospholipase A2 (PLA2)-catalyzed hydrolysis of dipalmitoylphosphatidylcholine (DPPC) liposomes incorporated with submicellar concentrations of polyethyleneoxide covalently attached to dipalmitoylphosphatidylethanolamine (DPPE-PEG2000) has been studied in the gel-to-fluid transition region of the host DPPC lipid bilayer matrix.	1,2-Dipalmitoylphosphatidylcholine	80-84	phospholipase A2 group IB	Homo sapiens	0-16
9733909-1	1998	Phospholipase A2 (PLA2)-catalyzed hydrolysis of dipalmitoylphosphatidylcholine (DPPC) liposomes incorporated with submicellar concentrations of polyethyleneoxide covalently attached to dipalmitoylphosphatidylethanolamine (DPPE-PEG2000) has been studied in the gel-to-fluid transition region of the host DPPC lipid bilayer matrix.	1,2-Dipalmitoylphosphatidylcholine	80-84	phospholipase A2 group IB	Homo sapiens	18-22
9733909-1	1998	Phospholipase A2 (PLA2)-catalyzed hydrolysis of dipalmitoylphosphatidylcholine (DPPC) liposomes incorporated with submicellar concentrations of polyethyleneoxide covalently attached to dipalmitoylphosphatidylethanolamine (DPPE-PEG2000) has been studied in the gel-to-fluid transition region of the host DPPC lipid bilayer matrix.	1,2-Dipalmitoylphosphatidylcholine	303-307	phospholipase A2 group IB	Homo sapiens	0-16
9733909-1	1998	Phospholipase A2 (PLA2)-catalyzed hydrolysis of dipalmitoylphosphatidylcholine (DPPC) liposomes incorporated with submicellar concentrations of polyethyleneoxide covalently attached to dipalmitoylphosphatidylethanolamine (DPPE-PEG2000) has been studied in the gel-to-fluid transition region of the host DPPC lipid bilayer matrix.	1,2-Dipalmitoylphosphatidylcholine	303-307	phospholipase A2 group IB	Homo sapiens	18-22
9858708-5	1998	Both proteins, TEMPO-SP-B and TEMPO-SP-C, showed considerable increases in mobility at temperatures above the pretransition of pure DPPC.	1,2-Dipalmitoylphosphatidylcholine	132-136	surfactant protein B	Homo sapiens	21-25
9858708-5	1998	Both proteins, TEMPO-SP-B and TEMPO-SP-C, showed considerable increases in mobility at temperatures above the pretransition of pure DPPC.	1,2-Dipalmitoylphosphatidylcholine	132-136	surfactant protein C	Homo sapiens	36-40
9858708-6	1998	Finally, the mobility of the spin probes attached to both SP-B and SP-C was more restricted in DPPG than in DPPC bilayers, demonstrating that electrostatic interactions of the positively charged residues at the protein surface influence the rotational dynamics of the proteins in anionic lipid bilayers.	1,2-Dipalmitoylphosphatidylcholine	108-112	surfactant protein B	Homo sapiens	58-62
9858708-6	1998	Finally, the mobility of the spin probes attached to both SP-B and SP-C was more restricted in DPPG than in DPPC bilayers, demonstrating that electrostatic interactions of the positively charged residues at the protein surface influence the rotational dynamics of the proteins in anionic lipid bilayers.	1,2-Dipalmitoylphosphatidylcholine	108-112	surfactant protein C	Homo sapiens	67-71
9748660-1	1998	Surfactant protein A (SP-A) binds to dipalmitoylphosphatidylcholine (DPPC) and induces phospholipid vesicle aggregation.	1,2-Dipalmitoylphosphatidylcholine	37-67	surfactant protein A1	Rattus norvegicus	0-20
9748660-1	1998	Surfactant protein A (SP-A) binds to dipalmitoylphosphatidylcholine (DPPC) and induces phospholipid vesicle aggregation.	1,2-Dipalmitoylphosphatidylcholine	37-67	surfactant protein A1	Rattus norvegicus	22-26
9748660-1	1998	Surfactant protein A (SP-A) binds to dipalmitoylphosphatidylcholine (DPPC) and induces phospholipid vesicle aggregation.	1,2-Dipalmitoylphosphatidylcholine	69-73	surfactant protein A1	Rattus norvegicus	0-20
9748660-1	1998	Surfactant protein A (SP-A) binds to dipalmitoylphosphatidylcholine (DPPC) and induces phospholipid vesicle aggregation.	1,2-Dipalmitoylphosphatidylcholine	69-73	surfactant protein A1	Rattus norvegicus	22-26
9685717-1	1998	The linoleic acids embedded in the SUVs of soy-PC, DMPC, and DPPC served as substrate for soybean lipoxygenase-1 (L-1).	1,2-Dipalmitoylphosphatidylcholine	61-65	seed linoleate 13S-lipoxygenase-1	Glycine max	98-112
9685717-1	1998	The linoleic acids embedded in the SUVs of soy-PC, DMPC, and DPPC served as substrate for soybean lipoxygenase-1 (L-1).	1,2-Dipalmitoylphosphatidylcholine	61-65	seed linoleate 13S-lipoxygenase-1	Glycine max	114-117
9685717-3	1998	The Km values of L-1 for the linoleic acids in soy-PC, DMPC, and DPPC vesicles were 0.07, 0.09, and 0.11 mM, respectively, being comparable with that for Tween-20 micellar linoleic acid.	1,2-Dipalmitoylphosphatidylcholine	65-69	seed linoleate 13S-lipoxygenase-1	Glycine max	17-20
9739568-0	1998	Interaction of human serum albumin with dipalmitoylphosphatidylcholine in spread monolayers at the air/water interface (short communication).	1,2-Dipalmitoylphosphatidylcholine	40-70	albumin	Homo sapiens	27-34
9692961-0	1998	Definition of the specific roles of lysolecithin and palmitic acid in altering the susceptibility of dipalmitoylphosphatidylcholine bilayers to phospholipase A2.	1,2-Dipalmitoylphosphatidylcholine	101-131	phospholipase A2 group IB	Homo sapiens	144-160
9649332-1	1998	Pulmonary surfactant-associated protein B (SP-B) has been isolated from porcine lungs and reconstituted in bilayers of dipalmitoylphosphatidylcholine (DPPC) or egg yolk phosphatidylcholine (PC) to characterize the extent of insertion of the protein into phospholipid bilayers.	1,2-Dipalmitoylphosphatidylcholine	119-149	surfactant protein B	Homo sapiens	43-47
9649332-1	1998	Pulmonary surfactant-associated protein B (SP-B) has been isolated from porcine lungs and reconstituted in bilayers of dipalmitoylphosphatidylcholine (DPPC) or egg yolk phosphatidylcholine (PC) to characterize the extent of insertion of the protein into phospholipid bilayers.	1,2-Dipalmitoylphosphatidylcholine	151-155	surfactant protein B	Homo sapiens	0-41
9649332-2	1998	The parameters for the interaction of SP-B with DPPC or PC using different reconstitution protocols have been estimated from the changes induced in the fluorescence emission spectrum of the single protein tryptophan.	1,2-Dipalmitoylphosphatidylcholine	48-52	surfactant protein B	Homo sapiens	38-42
9649332-7	1998	SP-B reconstituted from lipid/protein mixtures in organic solvents is inserted more deeply in PC or DPPC bilayers than the protein reconstituted by addition to preformed phospholipid vesicles.	1,2-Dipalmitoylphosphatidylcholine	100-104	surfactant protein B	Homo sapiens	0-4
9630660-2	1998	SP-B binding to membranes was studied by labeling the protein with the fluorophore 7-nitro-2,1,3-benzoxadiazol-4-yl (NBD) and measuring the fluorescence of the labeled protein in the presence of varying amounts of dipalmitoylphosphatidylcholine-egg phosphatidylglycerol (DPPC-eggPG; 7-3).	1,2-Dipalmitoylphosphatidylcholine	271-275	surfactant protein B	Homo sapiens	0-4
9512012-1	1998	The interaction of the pulmonary surfactant protein SP-A fluorescently labeled with Texas Red (TR-SP-A) with monolayers of dipalmitoylphosphatidylcholine (DPPC) and DPPC/dipalmitoylphosphatidylglycerol 7:3 w/w has been investigated.	1,2-Dipalmitoylphosphatidylcholine	123-153	surfactant protein A2	Homo sapiens	52-56
9518582-9	1998	The study suggests that the method of purification of SP-B and SP-C may modify their ability to enhance the adsorption rates of DPPC/protein mixtures, and this may be relevant to the formulation of protein-supplemented lipids for exogenous treatment of pulmonary surfactant insufficiency.	1,2-Dipalmitoylphosphatidylcholine	128-132	surfactant protein B	Homo sapiens	54-58
9518582-9	1998	The study suggests that the method of purification of SP-B and SP-C may modify their ability to enhance the adsorption rates of DPPC/protein mixtures, and this may be relevant to the formulation of protein-supplemented lipids for exogenous treatment of pulmonary surfactant insufficiency.	1,2-Dipalmitoylphosphatidylcholine	128-132	surfactant protein C	Homo sapiens	63-67
9576803-0	1998	Cascade liposomal triggering: light-induced Ca2+ release from diplasmenylcholine liposomes triggers PLA2-catalyzed hydrolysis and contents leakage from DPPC liposomes.	1,2-Dipalmitoylphosphatidylcholine	152-156	phospholipase A2 group IB	Homo sapiens	100-104
9576803-10	1998	Bacteriochlorophyll (BChl)-sensitized photorelease of Ca2+ from PLA2-resistant DPPlsCho liposomes activates extravesicular PLA2, thereby promoting catalyzed DPPC hydrolysis in a secondary triggering reaction, leading to calcein release.	1,2-Dipalmitoylphosphatidylcholine	157-161	phospholipase A2 group IB	Homo sapiens	64-68
9576803-10	1998	Bacteriochlorophyll (BChl)-sensitized photorelease of Ca2+ from PLA2-resistant DPPlsCho liposomes activates extravesicular PLA2, thereby promoting catalyzed DPPC hydrolysis in a secondary triggering reaction, leading to calcein release.	1,2-Dipalmitoylphosphatidylcholine	157-161	phospholipase A2 group IB	Homo sapiens	123-127
9591666-1	1998	We have investigated the time course of the degradation of a supported dipalmitoylphosphatidylcholine bilayer by phospholipase A2 in aqueous buffer with an atomic force microscope.	1,2-Dipalmitoylphosphatidylcholine	71-101	phospholipase A2 group IB	Homo sapiens	113-129
9512012-1	1998	The interaction of the pulmonary surfactant protein SP-A fluorescently labeled with Texas Red (TR-SP-A) with monolayers of dipalmitoylphosphatidylcholine (DPPC) and DPPC/dipalmitoylphosphatidylglycerol 7:3 w/w has been investigated.	1,2-Dipalmitoylphosphatidylcholine	123-153	surfactant protein A2	Homo sapiens	98-102
9512012-1	1998	The interaction of the pulmonary surfactant protein SP-A fluorescently labeled with Texas Red (TR-SP-A) with monolayers of dipalmitoylphosphatidylcholine (DPPC) and DPPC/dipalmitoylphosphatidylglycerol 7:3 w/w has been investigated.	1,2-Dipalmitoylphosphatidylcholine	155-159	surfactant protein A2	Homo sapiens	52-56
9512012-1	1998	The interaction of the pulmonary surfactant protein SP-A fluorescently labeled with Texas Red (TR-SP-A) with monolayers of dipalmitoylphosphatidylcholine (DPPC) and DPPC/dipalmitoylphosphatidylglycerol 7:3 w/w has been investigated.	1,2-Dipalmitoylphosphatidylcholine	165-169	surfactant protein A2	Homo sapiens	52-56
9512012-3	1998	TR-SP-A interacted with the monolayers of DPPC to accumulate at the boundary regions between liquid condensed (LC) and liquid expanded (LE) phases.	1,2-Dipalmitoylphosphatidylcholine	42-46	surfactant protein A2	Homo sapiens	3-7
9512012-6	1998	TR-SP-A interaction with DPPC/dipalmitoylphosphatidylglycerol monolayers was different.	1,2-Dipalmitoylphosphatidylcholine	25-29	surfactant protein A2	Homo sapiens	3-7
9512012-8	1998	The observations are consistent with a selectivity of interaction of SP-A with DPPC and for its accumulation in boundaries between LC and LE phase.	1,2-Dipalmitoylphosphatidylcholine	79-83	surfactant protein A2	Homo sapiens	69-73
9548588-0	1998	Interaction of pulmonary surfactant protein A with dipalmitoylphosphatidylcholine and cholesterol at the air/water interface.	1,2-Dipalmitoylphosphatidylcholine	51-81	surfactant protein A1	Homo sapiens	15-45
9548588-1	1998	Interaction of pulmonary surfactant protein A (SP-A) with pure and binary mixed dipalmitoylphosphatidylcholine (DPPC) and cholesterol (3.5 wt%) at the air/saline, 1.5 mM CaCl2 interface was investigated using a rhomboid surface balance at 37 degrees C. Surface tension-area isotherms were measured to access the surface active properties of the monolayers.	1,2-Dipalmitoylphosphatidylcholine	80-110	surfactant protein A1	Homo sapiens	47-51
9548588-1	1998	Interaction of pulmonary surfactant protein A (SP-A) with pure and binary mixed dipalmitoylphosphatidylcholine (DPPC) and cholesterol (3.5 wt%) at the air/saline, 1.5 mM CaCl2 interface was investigated using a rhomboid surface balance at 37 degrees C. Surface tension-area isotherms were measured to access the surface active properties of the monolayers.	1,2-Dipalmitoylphosphatidylcholine	112-116	surfactant protein A1	Homo sapiens	47-51
9548588-3	1998	The results showed that SP-A can interact with the polar head groups of DPPC monolayers and aggregate DPPC molecules.	1,2-Dipalmitoylphosphatidylcholine	72-76	surfactant protein A1	Homo sapiens	24-28
9548588-3	1998	The results showed that SP-A can interact with the polar head groups of DPPC monolayers and aggregate DPPC molecules.	1,2-Dipalmitoylphosphatidylcholine	102-106	surfactant protein A1	Homo sapiens	24-28
9548588-4	1998	SP-A decreased the surface area reduction required for DPPC monolayers to achieve near zero surface tension from 30 to 25% of the area at equilibrium.	1,2-Dipalmitoylphosphatidylcholine	55-59	surfactant protein A1	Homo sapiens	0-4
9548588-8	1998	Although SP-A could not promote the squeeze-out of cholesterol from homogeneous mixed monolayers, it facilitated that of cholesterol domains especially when SP-A had first interacted with DPPC.	1,2-Dipalmitoylphosphatidylcholine	188-192	surfactant protein A1	Homo sapiens	9-13
9548588-9	1998	These results indicate that pulmonary surfactant protein A facilitates the squeeze-out of cholesterol domains from mixed monolayers by condensing DPPC and limiting lateral interactions of DPPC with cholesterol domains.	1,2-Dipalmitoylphosphatidylcholine	146-150	surfactant protein A1	Homo sapiens	28-58
9548588-9	1998	These results indicate that pulmonary surfactant protein A facilitates the squeeze-out of cholesterol domains from mixed monolayers by condensing DPPC and limiting lateral interactions of DPPC with cholesterol domains.	1,2-Dipalmitoylphosphatidylcholine	188-192	surfactant protein A1	Homo sapiens	28-58
9315860-12	1997	However, in LCAT-treated spheroidal r-HDL, POPC = DOPC > PAPC/DPPC.	1,2-Dipalmitoylphosphatidylcholine	65-69	lecithin-cholesterol acyltransferase	Homo sapiens	12-16
9691465-3	1998	C6- and C8-ceramides increased the ordering of the DPPC acyl chains, correlating with the inhibition of PL-A2 activity which was probably due to the increased lateral surface pressure.	1,2-Dipalmitoylphosphatidylcholine	51-55	phospholipase A2 group IB	Homo sapiens	104-109
9468543-2	1998	SP-A binds to dipalmitoylphosphatidylcholine and galactosylceramide, and it regulates the uptake and secretion of surfactant lipids by alveolar type II cells.	1,2-Dipalmitoylphosphatidylcholine	14-44	surfactant protein A1	Rattus norvegicus	0-4
25125795-1	1998	The adsorption process of the recombinant human growth hormone on organic films, created by self-assembly of octadecyltrichlorosilane, arachidic acid, and dipalmitoylphosphatidylcholine, is investigated and compared to adsorption on silica and methylated silica substrates.	1,2-Dipalmitoylphosphatidylcholine	155-185	growth hormone 1	Homo sapiens	48-62
9774534-4	1998	Here, we have studied in vitro the effect of cations on the interaction of purified bovine SP-A with phospholipid vesicles made of dipalmitoylphosphatidylcholine and unsaturated phosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	131-161	pulmonary surfactant-associated protein A	Bos taurus	91-95
9436177-10	1998	On the other hand, SP-A significantly enhanced binding of dipalmitoyl phosphatidylcholine to plasma membranes (two- to threefold) and uptake into lamellar bodies (threefold) of 19-day fetal cells.	1,2-Dipalmitoylphosphatidylcholine	58-89	surfactant protein A1	Rattus norvegicus	19-23
9450240-3	1997	After the oral immunization of antigen (ganglioside GM1)-containing liposomes composed of DPPC, DPPS, and Chol (1:1:2, molar ratio) to mice, the serum IgA antibody responses against ganglioside GM1 were found.	1,2-Dipalmitoylphosphatidylcholine	90-94	coenzyme Q10A	Mus musculus	52-55
9450321-0	1997	Ganglioside GD3 and GD3-lactone mediated regulation of the intermolecular organization in mixed monolayers with dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	112-142	GRDX	Homo sapiens	12-15
9450321-0	1997	Ganglioside GD3 and GD3-lactone mediated regulation of the intermolecular organization in mixed monolayers with dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	112-142	GRDX	Homo sapiens	20-23
9450321-1	1997	The interactions of dpPC with ganglioside GD3 and two lactones.	1,2-Dipalmitoylphosphatidylcholine	20-24	GRDX	Homo sapiens	42-45
9450321-3	1997	dpPC is fully miscible with GD3 and GD3LacI but films with GD3LacII show immiscibility above 75 mol% lactone.	1,2-Dipalmitoylphosphatidylcholine	0-4	GRDX	Homo sapiens	28-31
9450321-4	1997	At low proportions of GD3 in mixtures with dpPC, GD3 undergoes condensation and depolarization; dpPC is depolarized and its molecular area is reduced above 50 mol% GD3.	1,2-Dipalmitoylphosphatidylcholine	43-47	GRDX	Homo sapiens	22-25
9450321-4	1997	At low proportions of GD3 in mixtures with dpPC, GD3 undergoes condensation and depolarization; dpPC is depolarized and its molecular area is reduced above 50 mol% GD3.	1,2-Dipalmitoylphosphatidylcholine	43-47	GRDX	Homo sapiens	49-52
9450321-4	1997	At low proportions of GD3 in mixtures with dpPC, GD3 undergoes condensation and depolarization; dpPC is depolarized and its molecular area is reduced above 50 mol% GD3.	1,2-Dipalmitoylphosphatidylcholine	43-47	GRDX	Homo sapiens	49-52
9370454-3	1997	In gel phase DPPC/DPPG (7:3) bilayers with one or the other lipid component chain-perdeuterated, SP-C was found to affect first spectral moment more strongly for DPPG-d62 than for DPPC-d62.	1,2-Dipalmitoylphosphatidylcholine	13-17	surfactant protein C	Homo sapiens	97-101
9434284-6	1997	METHODS: Epo was encapsulated in liposomes composed of dipalmitoylphosphatidylcholine (DPPC) and soybean-derived sterol mixture (SS) prepared by the reversed-phase evaporation vesicle method.	1,2-Dipalmitoylphosphatidylcholine	55-85	erythropoietin	Rattus norvegicus	9-12
9434284-6	1997	METHODS: Epo was encapsulated in liposomes composed of dipalmitoylphosphatidylcholine (DPPC) and soybean-derived sterol mixture (SS) prepared by the reversed-phase evaporation vesicle method.	1,2-Dipalmitoylphosphatidylcholine	87-91	erythropoietin	Rattus norvegicus	9-12
9371420-0	1997	Interaction of a synthetic peptide based on the neutrophil-derived antimicrobial protein CAP37 with dipalmitoyl-phosphatidylcholine membranes.	1,2-Dipalmitoylphosphatidylcholine	100-131	azurocidin 1	Homo sapiens	89-94
9371420-9	1997	The effect of the inactive peptide, CAP37 P20-44Ser on the thermotropic properties of DPPC was small.	1,2-Dipalmitoylphosphatidylcholine	86-90	azurocidin 1	Homo sapiens	36-41
9371426-12	1997	The replacement of DOPE by DPPC, or the addition of DPPE-PEG2000, restored NO and TNF-alpha synthesis by activated macrophages.	1,2-Dipalmitoylphosphatidylcholine	27-31	tumor necrosis factor	Homo sapiens	82-91
9355744-1	1997	Pulmonary surfactant-associated protein B (SP-B) has been incorporated into vesicles of dipalmitoyl phosphatidylcholine (DPPC) or egg yolk phosphatidylcholine (PC) by two different procedures to characterize the dependence of lipid-protein interactions on the method of reconstitution.	1,2-Dipalmitoylphosphatidylcholine	88-119	surfactant protein B	Homo sapiens	0-41
9357844-4	1997	The clearance of dipalmitoylphosphatidylcholine and SP-B from the airspaces was more rapid for GM-/-,SP-C-GM+/+ mice than for GM+/+ mice.	1,2-Dipalmitoylphosphatidylcholine	17-47	sparse coat	Mus musculus	101-105
9355744-1	1997	Pulmonary surfactant-associated protein B (SP-B) has been incorporated into vesicles of dipalmitoyl phosphatidylcholine (DPPC) or egg yolk phosphatidylcholine (PC) by two different procedures to characterize the dependence of lipid-protein interactions on the method of reconstitution.	1,2-Dipalmitoylphosphatidylcholine	88-119	surfactant protein B	Homo sapiens	43-47
9355744-1	1997	Pulmonary surfactant-associated protein B (SP-B) has been incorporated into vesicles of dipalmitoyl phosphatidylcholine (DPPC) or egg yolk phosphatidylcholine (PC) by two different procedures to characterize the dependence of lipid-protein interactions on the method of reconstitution.	1,2-Dipalmitoylphosphatidylcholine	121-125	surfactant protein B	Homo sapiens	0-41
9355744-1	1997	Pulmonary surfactant-associated protein B (SP-B) has been incorporated into vesicles of dipalmitoyl phosphatidylcholine (DPPC) or egg yolk phosphatidylcholine (PC) by two different procedures to characterize the dependence of lipid-protein interactions on the method of reconstitution.	1,2-Dipalmitoylphosphatidylcholine	121-125	surfactant protein B	Homo sapiens	43-47
9355744-5	1997	SP-B promoted the rapid adsorption of DPPC on an air/liquid interface irrespective of the method of protein reconstitution.	1,2-Dipalmitoylphosphatidylcholine	38-42	surfactant protein B	Homo sapiens	0-4
9355744-7	1997	Electron microscopy showed that the injection of SP-B into an aqueous phase containing PC or DPPC vesicles (method A) induced a rapid aggregation of vesicles.	1,2-Dipalmitoylphosphatidylcholine	93-97	surfactant protein B	Homo sapiens	49-53
9355744-9	1997	The presence of 5% (w/w) SP-B in DPPC bilayers prepared by method B broadened the differential scanning calorimetry thermogram and decreased the enthalpy of the transition.	1,2-Dipalmitoylphosphatidylcholine	33-37	surfactant protein B	Homo sapiens	25-29
9355744-10	1997	In contrast, the injection of SP-B into preformed DPPC vesicles (method A) did not influence the gel-to-liquid phase transition of DPPC bilayers.	1,2-Dipalmitoylphosphatidylcholine	50-54	surfactant protein B	Homo sapiens	30-34
9199807-4	1997	The interaction between rabbit CRP (rCRP) and model biological membrane is studied using dimyristoylphosphatidylethanolamine and dipalmitoylphosphatidylcholine monolayers.	1,2-Dipalmitoylphosphatidylcholine	129-159	C-reactive protein	Oryctolagus cuniculus	31-34
9315611-1	1997	Binding and localization of the vasodilator and antitumor drug coactivator dipyridamole (DIP) and one of its derivatives, RA25, to phospholipid vesicles of DMPC (dimyristoylphosphatidylcholine) and DPPC (dipalmitoylphosphatidylcholine) was studied using fluorescence spectroscopy as well as quenching of fluorescence.	1,2-Dipalmitoylphosphatidylcholine	198-202	RA25	Homo sapiens	122-126
9315611-1	1997	Binding and localization of the vasodilator and antitumor drug coactivator dipyridamole (DIP) and one of its derivatives, RA25, to phospholipid vesicles of DMPC (dimyristoylphosphatidylcholine) and DPPC (dipalmitoylphosphatidylcholine) was studied using fluorescence spectroscopy as well as quenching of fluorescence.	1,2-Dipalmitoylphosphatidylcholine	204-234	RA25	Homo sapiens	122-126
9219896-1	1997	The complexes of individual human plasma apolipoproteins (apo) A-I, E and A-II with dipalmitoylphosphatidylcholine (DPPC) in the absence or in the presence of cholesterol (Chol) were prepared with initial DPPC/Chol/protein weight ratio as 3:0.15:1.	1,2-Dipalmitoylphosphatidylcholine	84-114	NLR family pyrin domain containing 3	Homo sapiens	74-78
9188718-1	1997	Pulmonary surfactant protein A (SP-A) is a C-type lectin that regulates the uptake and secretion of surfactant lipids by alveolar type II cells and binds dipalmitoylphosphatidylcholine (DPPC) and galactosylceramide (GalCer).	1,2-Dipalmitoylphosphatidylcholine	154-184	surfactant protein A1	Rattus norvegicus	10-30
9188718-1	1997	Pulmonary surfactant protein A (SP-A) is a C-type lectin that regulates the uptake and secretion of surfactant lipids by alveolar type II cells and binds dipalmitoylphosphatidylcholine (DPPC) and galactosylceramide (GalCer).	1,2-Dipalmitoylphosphatidylcholine	154-184	surfactant protein A1	Rattus norvegicus	32-36
9188718-1	1997	Pulmonary surfactant protein A (SP-A) is a C-type lectin that regulates the uptake and secretion of surfactant lipids by alveolar type II cells and binds dipalmitoylphosphatidylcholine (DPPC) and galactosylceramide (GalCer).	1,2-Dipalmitoylphosphatidylcholine	186-190	surfactant protein A1	Rattus norvegicus	10-30
9188718-1	1997	Pulmonary surfactant protein A (SP-A) is a C-type lectin that regulates the uptake and secretion of surfactant lipids by alveolar type II cells and binds dipalmitoylphosphatidylcholine (DPPC) and galactosylceramide (GalCer).	1,2-Dipalmitoylphosphatidylcholine	186-190	surfactant protein A1	Rattus norvegicus	32-36
9219896-1	1997	The complexes of individual human plasma apolipoproteins (apo) A-I, E and A-II with dipalmitoylphosphatidylcholine (DPPC) in the absence or in the presence of cholesterol (Chol) were prepared with initial DPPC/Chol/protein weight ratio as 3:0.15:1.	1,2-Dipalmitoylphosphatidylcholine	116-120	NLR family pyrin domain containing 3	Homo sapiens	74-78
9219896-2	1997	ApoA-I/DPPC/Chol complexes with different protein content (initial DPPC/apoA-I weight ratios were changed from 10.5:1 to 2.6:1) but with a fixed initial DPPC/Chol weight ratio of 20:1 were also prepared.	1,2-Dipalmitoylphosphatidylcholine	67-71	apolipoprotein A1	Homo sapiens	0-6
9219896-2	1997	ApoA-I/DPPC/Chol complexes with different protein content (initial DPPC/apoA-I weight ratios were changed from 10.5:1 to 2.6:1) but with a fixed initial DPPC/Chol weight ratio of 20:1 were also prepared.	1,2-Dipalmitoylphosphatidylcholine	67-71	apolipoprotein A1	Homo sapiens	0-6
9219896-9	1997	(1) For apoA-I-complexes, the partition of cis-PA between water and lipid phase at temperatures below and above the transition temperature of DPPC (T(t)) was insensitive to Chol and temperature, while partition of trans-PA into the lipid phase of Chol-containing complex was increased at high temperature and decreased at low temperature.	1,2-Dipalmitoylphosphatidylcholine	142-146	apolipoprotein A1	Homo sapiens	8-14
9219896-12	1997	(2) The relative response of trans-PA fluorescence intensity to temperature-induced phase transition of DPPC in apoA-I/DPPC/Chol complexes was decreased as a function of apolipoprotein content in a non-monotonic fashion with a transition midpoint at a mol ratio DPPC/A-I of 250:1, probably indicating two different modes of apolipoprotein/DPPC interaction in different sized complexes.	1,2-Dipalmitoylphosphatidylcholine	104-108	apolipoprotein A1	Homo sapiens	112-118
9219896-12	1997	(2) The relative response of trans-PA fluorescence intensity to temperature-induced phase transition of DPPC in apoA-I/DPPC/Chol complexes was decreased as a function of apolipoprotein content in a non-monotonic fashion with a transition midpoint at a mol ratio DPPC/A-I of 250:1, probably indicating two different modes of apolipoprotein/DPPC interaction in different sized complexes.	1,2-Dipalmitoylphosphatidylcholine	104-108	apolipoprotein E	Homo sapiens	170-184
9219896-12	1997	(2) The relative response of trans-PA fluorescence intensity to temperature-induced phase transition of DPPC in apoA-I/DPPC/Chol complexes was decreased as a function of apolipoprotein content in a non-monotonic fashion with a transition midpoint at a mol ratio DPPC/A-I of 250:1, probably indicating two different modes of apolipoprotein/DPPC interaction in different sized complexes.	1,2-Dipalmitoylphosphatidylcholine	119-123	apolipoprotein A1	Homo sapiens	112-118
9219896-12	1997	(2) The relative response of trans-PA fluorescence intensity to temperature-induced phase transition of DPPC in apoA-I/DPPC/Chol complexes was decreased as a function of apolipoprotein content in a non-monotonic fashion with a transition midpoint at a mol ratio DPPC/A-I of 250:1, probably indicating two different modes of apolipoprotein/DPPC interaction in different sized complexes.	1,2-Dipalmitoylphosphatidylcholine	119-123	apolipoprotein E	Homo sapiens	170-184
9219896-12	1997	(2) The relative response of trans-PA fluorescence intensity to temperature-induced phase transition of DPPC in apoA-I/DPPC/Chol complexes was decreased as a function of apolipoprotein content in a non-monotonic fashion with a transition midpoint at a mol ratio DPPC/A-I of 250:1, probably indicating two different modes of apolipoprotein/DPPC interaction in different sized complexes.	1,2-Dipalmitoylphosphatidylcholine	119-123	apolipoprotein A1	Homo sapiens	112-118
9219896-12	1997	(2) The relative response of trans-PA fluorescence intensity to temperature-induced phase transition of DPPC in apoA-I/DPPC/Chol complexes was decreased as a function of apolipoprotein content in a non-monotonic fashion with a transition midpoint at a mol ratio DPPC/A-I of 250:1, probably indicating two different modes of apolipoprotein/DPPC interaction in different sized complexes.	1,2-Dipalmitoylphosphatidylcholine	119-123	apolipoprotein E	Homo sapiens	170-184
9219896-12	1997	(2) The relative response of trans-PA fluorescence intensity to temperature-induced phase transition of DPPC in apoA-I/DPPC/Chol complexes was decreased as a function of apolipoprotein content in a non-monotonic fashion with a transition midpoint at a mol ratio DPPC/A-I of 250:1, probably indicating two different modes of apolipoprotein/DPPC interaction in different sized complexes.	1,2-Dipalmitoylphosphatidylcholine	119-123	apolipoprotein A1	Homo sapiens	112-118
9219896-12	1997	(2) The relative response of trans-PA fluorescence intensity to temperature-induced phase transition of DPPC in apoA-I/DPPC/Chol complexes was decreased as a function of apolipoprotein content in a non-monotonic fashion with a transition midpoint at a mol ratio DPPC/A-I of 250:1, probably indicating two different modes of apolipoprotein/DPPC interaction in different sized complexes.	1,2-Dipalmitoylphosphatidylcholine	119-123	apolipoprotein E	Homo sapiens	170-184
9079687-6	1997	We demonstrate that iPLA2 selectively hydrolyzes the sn-2 over sn-1 fatty acid by 5-fold for 1,2-dipalmitoyl phosphatidylcholine in a mixed micelle.	1,2-Dipalmitoylphosphatidylcholine	93-128	phospholipase A2 group VI	Homo sapiens	20-25
9325267-1	1997	Previously we demonstrated that transmembrane back insertion of glycophorin A, a solubilizable intrinsic protein, can be obtained in dipalmitoylphosphatidylcholine multilamellar vesicles, MLVs, by electropulsation (Raffy, S., and Teissie, J.	1,2-Dipalmitoylphosphatidylcholine	133-163	glycophorin A (MNS blood group)	Homo sapiens	64-77
9100011-0	1997	Pulmonary surfactant protein SP-B interacts similarly with dipalmitoylphosphatidylglycerol and dipalmitoylphosphatidylcholine in phosphatidylcholine/phosphatidylglycerol mixtures.	1,2-Dipalmitoylphosphatidylcholine	95-125	surfactant protein B	Homo sapiens	29-33
9100011-1	1997	Porcine pulmonary surfactant-associated protein SP-B was incorporated into bilayers of chain-perdeuterated dipalmitoylphosphatidylglycerol (DPPG-d62) and into bilayers containing 70 mol % dipalmitoylphosphatidylcholine (DPPC) and 30 mol % DPPG-d62 or 70 mol % chain-perdeuterated DPPC (DPPC-d62) and 30 mol % DPPG.	1,2-Dipalmitoylphosphatidylcholine	188-218	surfactant protein B	Homo sapiens	48-52
9100011-1	1997	Porcine pulmonary surfactant-associated protein SP-B was incorporated into bilayers of chain-perdeuterated dipalmitoylphosphatidylglycerol (DPPG-d62) and into bilayers containing 70 mol % dipalmitoylphosphatidylcholine (DPPC) and 30 mol % DPPG-d62 or 70 mol % chain-perdeuterated DPPC (DPPC-d62) and 30 mol % DPPG.	1,2-Dipalmitoylphosphatidylcholine	220-224	surfactant protein B	Homo sapiens	48-52
9100011-1	1997	Porcine pulmonary surfactant-associated protein SP-B was incorporated into bilayers of chain-perdeuterated dipalmitoylphosphatidylglycerol (DPPG-d62) and into bilayers containing 70 mol % dipalmitoylphosphatidylcholine (DPPC) and 30 mol % DPPG-d62 or 70 mol % chain-perdeuterated DPPC (DPPC-d62) and 30 mol % DPPG.	1,2-Dipalmitoylphosphatidylcholine	280-284	surfactant protein B	Homo sapiens	48-52
9100011-5	1997	Despite its limited effect on chain order in these bilayers, SP-B is found to strongly perturb chain deuteron transverse relaxation in the liquid crystal and gel phases of DPPG-d62 and the DPPC/DPPG (7:3) mixtures.	1,2-Dipalmitoylphosphatidylcholine	189-193	surfactant protein B	Homo sapiens	61-65
9275298-4	1997	Association of apoE3 with DPPC resulted in a more structured state of the apolipoprotein molecule versus the soluble apolipoprotein; this state was characterized by parallel orientation of alpha-helixes of apoE3 and DPPC acyl chains.	1,2-Dipalmitoylphosphatidylcholine	26-30	apolipoprotein E	Homo sapiens	15-20
9108235-10	1997	SP-C is a lipopeptide containing covalently linked palmitoyl chains and is folded into a 3.7-nm alpha-helix with a central 2.3-nm all-aliphatic part, making it perfectly suited to interact in a transmembranous way with a fluid bilayer composed of dipalmitoylglycerophosphocholine, the main component of surfactant.	1,2-Dipalmitoylphosphatidylcholine	247-279	surfactant protein C	Homo sapiens	0-4
9084505-0	1997	Surface properties after a simulated PLA2 hydrolysis of pulmonary surfactant"s main component, DPPC.	1,2-Dipalmitoylphosphatidylcholine	95-99	phospholipase A2 group IB	Homo sapiens	37-41
9275298-4	1997	Association of apoE3 with DPPC resulted in a more structured state of the apolipoprotein molecule versus the soluble apolipoprotein; this state was characterized by parallel orientation of alpha-helixes of apoE3 and DPPC acyl chains.	1,2-Dipalmitoylphosphatidylcholine	26-30	apolipoprotein E	Homo sapiens	74-88
9275298-4	1997	Association of apoE3 with DPPC resulted in a more structured state of the apolipoprotein molecule versus the soluble apolipoprotein; this state was characterized by parallel orientation of alpha-helixes of apoE3 and DPPC acyl chains.	1,2-Dipalmitoylphosphatidylcholine	26-30	apolipoprotein E	Homo sapiens	206-211
9275298-6	1997	The transformation of discoidal apoE3-DPPC-Chol complexes into spherical particles was induced by LCAT and accumulation of cholesteryl esters was approximately 62% of the total cholesterol.	1,2-Dipalmitoylphosphatidylcholine	38-42	apolipoprotein E	Homo sapiens	32-37
9275298-6	1997	The transformation of discoidal apoE3-DPPC-Chol complexes into spherical particles was induced by LCAT and accumulation of cholesteryl esters was approximately 62% of the total cholesterol.	1,2-Dipalmitoylphosphatidylcholine	38-42	lecithin-cholesterol acyltransferase	Homo sapiens	98-102
9275298-8	1997	Discoidal apoE3-DPPC complexes incorporated unesterified cholesterol released from Chol-loaded J774 macrophages.	1,2-Dipalmitoylphosphatidylcholine	16-20	apolipoprotein E	Homo sapiens	10-15
8725157-8	1996	The results of this study indicate that aiPLA2 has the major role in the degradation of internalized DPPC by granular pneumocytes and they are compatible with participation of lysosomes/lamellar bodies in DPPC metabolism.	1,2-Dipalmitoylphosphatidylcholine	101-105	peroxiredoxin 6	Rattus norvegicus	40-46
9124374-0	1997	Role of acidic Ca2+-independent phospholipase A2 in synthesis of lung dipalmitoyl phosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	70-101	phospholipase A2 group IB	Rattus norvegicus	32-48
9124374-1	1997	Dipalmitoyl phosphatidylcholine (deltaPC) synthesis by lung epithelium occurs in part by a deacylation/reacylation pathway utilizing phospholipase A2 (PLA2) and an acyl transferase.	1,2-Dipalmitoylphosphatidylcholine	0-31	phospholipase A2 group IB	Rattus norvegicus	133-149
9124374-1	1997	Dipalmitoyl phosphatidylcholine (deltaPC) synthesis by lung epithelium occurs in part by a deacylation/reacylation pathway utilizing phospholipase A2 (PLA2) and an acyl transferase.	1,2-Dipalmitoylphosphatidylcholine	0-31	phospholipase A2 group IB	Rattus norvegicus	151-155
9020791-5	1997	In contrast, CH appeared to enhance the mixing of SP-C with DPPC/CH in ternary SP-C/(DPPC/CH) films compared to the miscibility of SP-C with DPPC in the SP-C/DPPC films.	1,2-Dipalmitoylphosphatidylcholine	60-64	surfactant protein C	Homo sapiens	79-83
9020791-5	1997	In contrast, CH appeared to enhance the mixing of SP-C with DPPC/CH in ternary SP-C/(DPPC/CH) films compared to the miscibility of SP-C with DPPC in the SP-C/DPPC films.	1,2-Dipalmitoylphosphatidylcholine	60-64	surfactant protein C	Homo sapiens	79-83
9020791-5	1997	In contrast, CH appeared to enhance the mixing of SP-C with DPPC/CH in ternary SP-C/(DPPC/CH) films compared to the miscibility of SP-C with DPPC in the SP-C/DPPC films.	1,2-Dipalmitoylphosphatidylcholine	60-64	surfactant protein C	Homo sapiens	79-83
9020791-5	1997	In contrast, CH appeared to enhance the mixing of SP-C with DPPC/CH in ternary SP-C/(DPPC/CH) films compared to the miscibility of SP-C with DPPC in the SP-C/DPPC films.	1,2-Dipalmitoylphosphatidylcholine	85-89	surfactant protein C	Homo sapiens	50-54
9020791-5	1997	In contrast, CH appeared to enhance the mixing of SP-C with DPPC/CH in ternary SP-C/(DPPC/CH) films compared to the miscibility of SP-C with DPPC in the SP-C/DPPC films.	1,2-Dipalmitoylphosphatidylcholine	85-89	surfactant protein C	Homo sapiens	50-54
9020791-5	1997	In contrast, CH appeared to enhance the mixing of SP-C with DPPC/CH in ternary SP-C/(DPPC/CH) films compared to the miscibility of SP-C with DPPC in the SP-C/DPPC films.	1,2-Dipalmitoylphosphatidylcholine	85-89	surfactant protein C	Homo sapiens	50-54
9020791-6	1997	It is estimated that about 10 wt % SP-C might remain in the SP-C/(DPPC/CH) monolayers compressed to high surface pressures of about 72 mN/m, whereas SP-C at concentrations of > or = 5 wt % was squeezed out at pi approximately 50 mN/m from SP-C/DPPC films without cholesterol.	1,2-Dipalmitoylphosphatidylcholine	66-70	surfactant protein C	Homo sapiens	35-39
9020791-6	1997	It is estimated that about 10 wt % SP-C might remain in the SP-C/(DPPC/CH) monolayers compressed to high surface pressures of about 72 mN/m, whereas SP-C at concentrations of > or = 5 wt % was squeezed out at pi approximately 50 mN/m from SP-C/DPPC films without cholesterol.	1,2-Dipalmitoylphosphatidylcholine	66-70	surfactant protein C	Homo sapiens	60-64
9020791-6	1997	It is estimated that about 10 wt % SP-C might remain in the SP-C/(DPPC/CH) monolayers compressed to high surface pressures of about 72 mN/m, whereas SP-C at concentrations of > or = 5 wt % was squeezed out at pi approximately 50 mN/m from SP-C/DPPC films without cholesterol.	1,2-Dipalmitoylphosphatidylcholine	66-70	surfactant protein C	Homo sapiens	60-64
8968592-9	1996	The miscibility in DMPG/DPPC and DMPA/DPPC mixtures differs remarkably because, for DMPG/DPPC, delta rho = rho l -rho g is negative, whereas for DMPA/DPPC this difference is positive.	1,2-Dipalmitoylphosphatidylcholine	38-42	ras homolog family member G	Homo sapiens	114-119
8968592-9	1996	The miscibility in DMPG/DPPC and DMPA/DPPC mixtures differs remarkably because, for DMPG/DPPC, delta rho = rho l -rho g is negative, whereas for DMPA/DPPC this difference is positive.	1,2-Dipalmitoylphosphatidylcholine	38-42	ras homolog family member G	Homo sapiens	114-119
8968592-9	1996	The miscibility in DMPG/DPPC and DMPA/DPPC mixtures differs remarkably because, for DMPG/DPPC, delta rho = rho l -rho g is negative, whereas for DMPA/DPPC this difference is positive.	1,2-Dipalmitoylphosphatidylcholine	38-42	ras homolog family member G	Homo sapiens	114-119
8968592-10	1996	For DMPA/DPPC, this difference is interpreted as being caused by a negative rho g value, indicating complex formation of unlike molecules in the gel phase.	1,2-Dipalmitoylphosphatidylcholine	9-13	ras homolog family member G	Homo sapiens	76-81
8948468-7	1996	Addition of the positively charged SP-B to a mixture of DPPC and PG, led to an increase of approximately 20% in E/M ratio, indicating a clustering of the negatively charged PG molecules.	1,2-Dipalmitoylphosphatidylcholine	56-60	surfactant protein B	Homo sapiens	35-39
8920991-5	1996	C10-PC was compared with the commonly used dipalmitoyl phosphatidylcholine (C16-PC) as a substrate for PLD activity from membranes of human neutrophils, human placenta and pig brain, and from placental cytosol.	1,2-Dipalmitoylphosphatidylcholine	43-74	glycosylphosphatidylinositol specific phospholipase D1	Homo sapiens	103-106
8897904-1	1996	The effect of palmitoylation of pulmonary surfactant-associated protein C (SP-C) on the surface activity of phospholipid mixtures of dipalmitoylphosphatidylcholine and phosphatidylglycerol was studied.	1,2-Dipalmitoylphosphatidylcholine	133-163	surfactant protein C	Bos taurus	32-73
8897904-1	1996	The effect of palmitoylation of pulmonary surfactant-associated protein C (SP-C) on the surface activity of phospholipid mixtures of dipalmitoylphosphatidylcholine and phosphatidylglycerol was studied.	1,2-Dipalmitoylphosphatidylcholine	133-163	surfactant protein C	Bos taurus	75-79
8913267-4	1996	The in vitro phospholipase A2 activity apparent in the C3H10T1/2 showed preference for sn-2 arachidonyl phosphatidylcholine compared to dipalmitoyl phosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	136-167	phospholipase A2, group IB, pancreas	Mus musculus	13-29
8874011-2	1996	Epifluorescence microscopy of monolayers spontaneously adsorbed from vesicles of dipalmitoylphosphatidylcholine or dipalmitoylphosphatidylcholine plus surfactant protein C (SP-C) showed gas, liquid expanded, and liquid condensed (LC) domains.	1,2-Dipalmitoylphosphatidylcholine	115-145	surfactant protein C	Homo sapiens	173-177
8652605-1	1996	Pulmonary surfactant protein A (SP-A) augments the uptake of phospholipid liposomes containing dipalmitoylphosphatidylcholine (DPPC) by alveolar type II cells.	1,2-Dipalmitoylphosphatidylcholine	95-125	surfactant protein A1	Homo sapiens	0-30
8652605-1	1996	Pulmonary surfactant protein A (SP-A) augments the uptake of phospholipid liposomes containing dipalmitoylphosphatidylcholine (DPPC) by alveolar type II cells.	1,2-Dipalmitoylphosphatidylcholine	95-125	surfactant protein A1	Homo sapiens	32-36
8652605-1	1996	Pulmonary surfactant protein A (SP-A) augments the uptake of phospholipid liposomes containing dipalmitoylphosphatidylcholine (DPPC) by alveolar type II cells.	1,2-Dipalmitoylphosphatidylcholine	127-131	surfactant protein A1	Homo sapiens	0-30
8652605-1	1996	Pulmonary surfactant protein A (SP-A) augments the uptake of phospholipid liposomes containing dipalmitoylphosphatidylcholine (DPPC) by alveolar type II cells.	1,2-Dipalmitoylphosphatidylcholine	127-131	surfactant protein A1	Homo sapiens	32-36
8652605-4	1996	SP-A increased the amount of liposomes containing radiolabeled DPPC associated with type II cell plasma membrane by 4-fold compared to the control without SP-A when analyzed by sucrose density gradient centrifugation.	1,2-Dipalmitoylphosphatidylcholine	63-67	surfactant protein A1	Homo sapiens	0-4
8652605-7	1996	When type II cell plasma membrane and liposomes containing [14C]DPPC and [3H]triolein were coincubated with or without SP-A, analysis on sucrose density gradients revealed that the profiles of [14C]DPPC and [3H]triolein in each fraction were almost identical with or without SP-A, indicating that SP-A mediates the binding of liposomes to plasma membrane but not transfer of DPPC.	1,2-Dipalmitoylphosphatidylcholine	198-202	surfactant protein A1	Homo sapiens	119-123
8652605-7	1996	When type II cell plasma membrane and liposomes containing [14C]DPPC and [3H]triolein were coincubated with or without SP-A, analysis on sucrose density gradients revealed that the profiles of [14C]DPPC and [3H]triolein in each fraction were almost identical with or without SP-A, indicating that SP-A mediates the binding of liposomes to plasma membrane but not transfer of DPPC.	1,2-Dipalmitoylphosphatidylcholine	198-202	surfactant protein A1	Homo sapiens	119-123
8725157-0	1996	Role of phospholipase A2 enzymes in degradation of dipalmitoylphosphatidylcholine by granular pneumocytes.	1,2-Dipalmitoylphosphatidylcholine	51-81	phospholipase A2 group IB	Rattus norvegicus	8-24
8725157-1	1996	The role of phospholipase A2 (PLA2) enzymes in the degradation of internalized dipalmitoylphospharidylcoline (DPPC) by rat granular pneumocytes was evaluated with cells in 24 h primary culture on microporous membranes.	1,2-Dipalmitoylphosphatidylcholine	110-114	phospholipase A2 group IB	Rattus norvegicus	12-28
8725157-1	1996	The role of phospholipase A2 (PLA2) enzymes in the degradation of internalized dipalmitoylphospharidylcoline (DPPC) by rat granular pneumocytes was evaluated with cells in 24 h primary culture on microporous membranes.	1,2-Dipalmitoylphosphatidylcholine	110-114	phospholipase A2 group IB	Rattus norvegicus	30-34
8726232-6	1996	The adsorption of dispersions containing 40% DPPC with 1.3% SP-B, C was almost identical to CLSE and was improved in rate and magnitude compared with the mixtures with higher DPPC content (60 or 80%).	1,2-Dipalmitoylphosphatidylcholine	45-49	surfactant protein B	Bos taurus	60-64
8664287-0	1996	Relationships between bilayer structure and phospholipase A2 activity: interactions among temperature, diacylglycerol, lysolecithin, palmitic acid, and dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	152-182	phospholipase A2 group IB	Homo sapiens	44-60
8829604-1	1996	Complexes of alpha-lactalbumin (alpha-LA)1 with dimyristoylphosphatidylcholine (DMPC) or dipalmitoylphosphatidylcholine (DPPC) liposomes at pH 8 and at pH 2 have been obtained by means of gel filtration.	1,2-Dipalmitoylphosphatidylcholine	89-119	lactalbumin alpha	Homo sapiens	13-30
8829604-1	1996	Complexes of alpha-lactalbumin (alpha-LA)1 with dimyristoylphosphatidylcholine (DMPC) or dipalmitoylphosphatidylcholine (DPPC) liposomes at pH 8 and at pH 2 have been obtained by means of gel filtration.	1,2-Dipalmitoylphosphatidylcholine	121-125	lactalbumin alpha	Homo sapiens	13-30
9376129-1	1997	Total internal reflection fluorescence microscopy has been used to investigate the binding of the soluble extracellular domain of mouse Fc gamma RII (sFc gamma RII) to an anti-trinitrophenyl monoclonal mouse IgG2b (GK14.1) specifically bound to substrate-supported planar membranes composed of dipalmitoylphosphatidylcholine (DPPC) and trinitrophenylaminocaproyldipalmitoylphosphatidylethanolamine (TNP-cap-DPPE).	1,2-Dipalmitoylphosphatidylcholine	294-324	Fc receptor, IgG, low affinity IIb	Mus musculus	136-148
9376129-1	1997	Total internal reflection fluorescence microscopy has been used to investigate the binding of the soluble extracellular domain of mouse Fc gamma RII (sFc gamma RII) to an anti-trinitrophenyl monoclonal mouse IgG2b (GK14.1) specifically bound to substrate-supported planar membranes composed of dipalmitoylphosphatidylcholine (DPPC) and trinitrophenylaminocaproyldipalmitoylphosphatidylethanolamine (TNP-cap-DPPE).	1,2-Dipalmitoylphosphatidylcholine	326-330	Fc receptor, IgG, low affinity IIb	Mus musculus	136-148
9020791-6	1997	It is estimated that about 10 wt % SP-C might remain in the SP-C/(DPPC/CH) monolayers compressed to high surface pressures of about 72 mN/m, whereas SP-C at concentrations of > or = 5 wt % was squeezed out at pi approximately 50 mN/m from SP-C/DPPC films without cholesterol.	1,2-Dipalmitoylphosphatidylcholine	66-70	surfactant protein C	Homo sapiens	60-64
9020791-6	1997	It is estimated that about 10 wt % SP-C might remain in the SP-C/(DPPC/CH) monolayers compressed to high surface pressures of about 72 mN/m, whereas SP-C at concentrations of > or = 5 wt % was squeezed out at pi approximately 50 mN/m from SP-C/DPPC films without cholesterol.	1,2-Dipalmitoylphosphatidylcholine	247-251	surfactant protein C	Homo sapiens	35-39
8999971-5	1997	Apparent kinetic constants for PLA2 with dipalmitoylphosphatidylcholine as substrate were Km = 0.25 mM and Vmax = 1.89 nmol/h.	1,2-Dipalmitoylphosphatidylcholine	41-71	phospholipase A2 group IB	Rattus norvegicus	31-35
9003195-2	1997	A slight perturbation was established in the outer leaflets of DPPC LUVs by hydrolyzing 0.8% of the outer leaflet lipid with phospholipase A2 to produce lysophosphatidylcholine and palmitate which were then removed by bovine serum albumin.	1,2-Dipalmitoylphosphatidylcholine	63-67	phospholipase A2 group IB	Homo sapiens	125-141
8843792-4	1996	With 5 micrograms/ml SP-A, type II cells actively take up liposomes (244 pmol dipalmitoylphosphatidylcholine.h-1.10(6) cells-1).	1,2-Dipalmitoylphosphatidylcholine	78-108	surfactant protein A1	Rattus norvegicus	21-25
8702584-3	1996	Deacylated SP-C (dSP-C), unchanged in composition and sequence from SP-C but having a decreased alpha-helical content in films with dipalmitoyl phosphatidylcholine (DPPC) of 52 versus 70%, was obtained by treatment with 0.1 M sodium carbonate buffer at pH 10.	1,2-Dipalmitoylphosphatidylcholine	132-163	surfactant protein C	Bos taurus	11-15
8702584-3	1996	Deacylated SP-C (dSP-C), unchanged in composition and sequence from SP-C but having a decreased alpha-helical content in films with dipalmitoyl phosphatidylcholine (DPPC) of 52 versus 70%, was obtained by treatment with 0.1 M sodium carbonate buffer at pH 10.	1,2-Dipalmitoylphosphatidylcholine	165-169	surfactant protein C	Bos taurus	11-15
8960386-6	1996	In both Survanta and DPPC preparations, PLA2-mediated deacylation was significantly inhibited in the presence of tyloxapol.	1,2-Dipalmitoylphosphatidylcholine	21-25	phospholipase A2 group IB	Homo sapiens	40-44
8960386-7	1996	We conclude that the presence of tyloxapol in the Exosurf preparation inhibits secretory type PLA2 mediated DPPC deacylation.	1,2-Dipalmitoylphosphatidylcholine	108-112	phospholipase A2 group IB	Homo sapiens	94-98
8864959-5	1996	Interfacial films of DPPC or SPL plus 1.3% SP-B or 1.3% SP-C had improved respreading compared to phospholipids alone (Wilhelmy balance, 23 degrees C and 37 degrees C), but substitution of mixed SP-B/C for either pure apoprotein did not increase respreading further.	1,2-Dipalmitoylphosphatidylcholine	21-25	surfactant protein B	Bos taurus	195-199
8652189-9	1996	Both APP-I and APP-II retained the abilities to bind dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	53-83	amyloid beta precursor protein	Homo sapiens	5-10
8652189-9	1996	Both APP-I and APP-II retained the abilities to bind dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	85-89	amyloid beta precursor protein	Homo sapiens	5-10
8808762-3	1996	SP-A enhanced the rate of lipid adsorption, while both SP-A and NL increased the extent of DPPC accumulation.	1,2-Dipalmitoylphosphatidylcholine	91-95	pulmonary surfactant-associated protein A	Bos taurus	55-59
8808762-8	1996	Addition of SP-A to lipid extracts without NL generated DPPC aggregates; more uniform larger aggregates appeared in the presence of SP-A and NL.	1,2-Dipalmitoylphosphatidylcholine	56-60	pulmonary surfactant-associated protein A	Bos taurus	12-16
8808762-11	1996	These results indicate that neutral lipid cooperates with surfactant-associated protein A to organize dipalmitoylphosphatidylcholine in the surface films and enhance formation of a DPPC-rich reservoir below the air-water interface.	1,2-Dipalmitoylphosphatidylcholine	102-132	pulmonary surfactant-associated protein A	Bos taurus	58-89
8808762-11	1996	These results indicate that neutral lipid cooperates with surfactant-associated protein A to organize dipalmitoylphosphatidylcholine in the surface films and enhance formation of a DPPC-rich reservoir below the air-water interface.	1,2-Dipalmitoylphosphatidylcholine	181-185	pulmonary surfactant-associated protein A	Bos taurus	58-89
8639617-5	1996	In contrast, in DPPC the results suggest that although the CBS long chain interdigitates across the center of the bilayer, it does not change the tilt angle of the DPPC molecules in the gel phase.	1,2-Dipalmitoylphosphatidylcholine	16-20	cystathionine beta-synthase	Homo sapiens	59-62
8639617-6	1996	Furthermore, in DPPC, C26-CBS is less well oriented than the host DPPC molecules and it increases the gauche content of the DPPC acyl chains.	1,2-Dipalmitoylphosphatidylcholine	16-20	cystathionine beta-synthase	Homo sapiens	26-29
8639617-6	1996	Furthermore, in DPPC, C26-CBS is less well oriented than the host DPPC molecules and it increases the gauche content of the DPPC acyl chains.	1,2-Dipalmitoylphosphatidylcholine	66-70	cystathionine beta-synthase	Homo sapiens	26-29
8639617-6	1996	Furthermore, in DPPC, C26-CBS is less well oriented than the host DPPC molecules and it increases the gauche content of the DPPC acyl chains.	1,2-Dipalmitoylphosphatidylcholine	66-70	cystathionine beta-synthase	Homo sapiens	26-29
8639617-8	1996	The thermotropic behavior of the lipid mixtures of C26-CBS at 8 mol % in DMPC or DPPC shows that the glycosphingolipid stabilizes the gel phase of the short chain length bilayer while it destabilizes the long chain length one.	1,2-Dipalmitoylphosphatidylcholine	81-85	cystathionine beta-synthase	Homo sapiens	55-58
8639617-9	1996	Our results further demonstrate that, at this concentration, C26-CBS is completely miscible in DMPC and DPPC in the gel and the liquid crystalline phases.	1,2-Dipalmitoylphosphatidylcholine	104-108	cystathionine beta-synthase	Homo sapiens	65-68
8639617-10	1996	The difference in behavior of C26-CBS in DMPC and DPPC is a consequence of the greater mismatch between the C26 chain length and the bilayer thickness of DPPC relative to DMPC.	1,2-Dipalmitoylphosphatidylcholine	50-54	cystathionine beta-synthase	Homo sapiens	34-37
8639617-10	1996	The difference in behavior of C26-CBS in DMPC and DPPC is a consequence of the greater mismatch between the C26 chain length and the bilayer thickness of DPPC relative to DMPC.	1,2-Dipalmitoylphosphatidylcholine	154-158	cystathionine beta-synthase	Homo sapiens	34-37
8652605-8	1996	SP-A increased the association of liposomes containing DPPC with the membrane by 2-fold more than that containing 1-palmitoyl-2-linoleoyl-phosphatidylcholine (PLPC).	1,2-Dipalmitoylphosphatidylcholine	55-59	surfactant protein A1	Homo sapiens	0-4
8652605-9	1996	SP-A induced aggregation of phospholipid liposomes containing PLPC as well as those containing DPPC, but the final turbidity of DPPC liposomes aggregated by SP-A was only by 15% greater than that of PLPC liposomes.	1,2-Dipalmitoylphosphatidylcholine	95-99	surfactant protein A1	Homo sapiens	0-4
8652605-9	1996	SP-A induced aggregation of phospholipid liposomes containing PLPC as well as those containing DPPC, but the final turbidity of DPPC liposomes aggregated by SP-A was only by 15% greater than that of PLPC liposomes.	1,2-Dipalmitoylphosphatidylcholine	128-132	surfactant protein A1	Homo sapiens	157-161
8814646-6	1996	Water shifted the P-31 resonant frequency of DPPC downfield, and the effect magnitude varied with water concentration.	1,2-Dipalmitoylphosphatidylcholine	45-49	ATPase H+ transporting V1 subunit E1	Homo sapiens	18-22
8611021-5	1996	A liposome binding assay using Ficoll density gradient centrifugation revealed that incubating the N-myristoylated fusion TNF with dipalmitoyl phosphatidylcholine-liposomes caused the complete binding of the protein to the liposomes, whereas much less of the nonmyristoylated counterpart bound.	1,2-Dipalmitoylphosphatidylcholine	131-162	tumor necrosis factor	Oryctolagus cuniculus	122-125
8725157-8	1996	The results of this study indicate that aiPLA2 has the major role in the degradation of internalized DPPC by granular pneumocytes and they are compatible with participation of lysosomes/lamellar bodies in DPPC metabolism.	1,2-Dipalmitoylphosphatidylcholine	205-209	peroxiredoxin 6	Rattus norvegicus	40-46
8599660-1	1995	The interactions of the hydrophobic pulmonary surfactant proteins SP-B and SP-C with 1,2-dipalmitoylphosphatidylcholine in mixed, spread monolayer films have been studied in situ at the air/water interface with the technique of external reflection absorption infrared spectroscopy (IRRAS).	1,2-Dipalmitoylphosphatidylcholine	85-119	surfactant protein B	Homo sapiens	66-70
8770209-8	1996	Indicating that the newly formed DPPC emulsion-Apo-A1 complex is thermally reversible during calorimetry.	1,2-Dipalmitoylphosphatidylcholine	33-37	apolipoprotein A1	Homo sapiens	47-53
8770209-9	1996	Thus there is an increase in delta H of 1.17 kcal mol-1 DPPC after apo-A1 is bound, which is roughly balanced by the heat released during binding (-0.92 kcal) of apo-A1.	1,2-Dipalmitoylphosphatidylcholine	56-60	apolipoprotein A1	Homo sapiens	67-73
8770209-9	1996	Thus there is an increase in delta H of 1.17 kcal mol-1 DPPC after apo-A1 is bound, which is roughly balanced by the heat released during binding (-0.92 kcal) of apo-A1.	1,2-Dipalmitoylphosphatidylcholine	56-60	apolipoprotein A1	Homo sapiens	162-168
8770209-10	1996	The melting entropy increase, +3.8 cal deg-1 mol-1 DPPC of the three transitions after apo-A1 binds, also roughly balances the entropy (-3 cal deg-1 mol-1 DPPC) of association of apo-A1.	1,2-Dipalmitoylphosphatidylcholine	51-55	apolipoprotein A1	Homo sapiens	87-93
8770209-10	1996	The melting entropy increase, +3.8 cal deg-1 mol-1 DPPC of the three transitions after apo-A1 binds, also roughly balances the entropy (-3 cal deg-1 mol-1 DPPC) of association of apo-A1.	1,2-Dipalmitoylphosphatidylcholine	51-55	apolipoprotein A1	Homo sapiens	179-185
8770209-10	1996	The melting entropy increase, +3.8 cal deg-1 mol-1 DPPC of the three transitions after apo-A1 binds, also roughly balances the entropy (-3 cal deg-1 mol-1 DPPC) of association of apo-A1.	1,2-Dipalmitoylphosphatidylcholine	155-159	apolipoprotein A1	Homo sapiens	87-93
8770209-10	1996	The melting entropy increase, +3.8 cal deg-1 mol-1 DPPC of the three transitions after apo-A1 binds, also roughly balances the entropy (-3 cal deg-1 mol-1 DPPC) of association of apo-A1.	1,2-Dipalmitoylphosphatidylcholine	155-159	apolipoprotein A1	Homo sapiens	179-185
8770209-11	1996	These changes indicate that apo-A1 increases the amount of ordered gel-like phase on the surface of DPPC emulsions when added at 30 degrees C. From the stoichiometry of the emulsions we calculate that the mean area of DPPC at the triolein/DPPC interface is 54.5 A2 at 41 degrees C and 54.2 A2 at 30 degrees C. The binding of apo-A1 at 30 degrees C to the emulsion reduces the surface area per DPPC molecule from 54.2 A2 to 50.8 A2.	1,2-Dipalmitoylphosphatidylcholine	100-104	apolipoprotein A1	Homo sapiens	28-34
8770209-11	1996	These changes indicate that apo-A1 increases the amount of ordered gel-like phase on the surface of DPPC emulsions when added at 30 degrees C. From the stoichiometry of the emulsions we calculate that the mean area of DPPC at the triolein/DPPC interface is 54.5 A2 at 41 degrees C and 54.2 A2 at 30 degrees C. The binding of apo-A1 at 30 degrees C to the emulsion reduces the surface area per DPPC molecule from 54.2 A2 to 50.8 A2.	1,2-Dipalmitoylphosphatidylcholine	218-222	apolipoprotein A1	Homo sapiens	28-34
8770209-11	1996	These changes indicate that apo-A1 increases the amount of ordered gel-like phase on the surface of DPPC emulsions when added at 30 degrees C. From the stoichiometry of the emulsions we calculate that the mean area of DPPC at the triolein/DPPC interface is 54.5 A2 at 41 degrees C and 54.2 A2 at 30 degrees C. The binding of apo-A1 at 30 degrees C to the emulsion reduces the surface area per DPPC molecule from 54.2 A2 to 50.8 A2.	1,2-Dipalmitoylphosphatidylcholine	218-222	apolipoprotein A1	Homo sapiens	325-331
8770209-11	1996	These changes indicate that apo-A1 increases the amount of ordered gel-like phase on the surface of DPPC emulsions when added at 30 degrees C. From the stoichiometry of the emulsions we calculate that the mean area of DPPC at the triolein/DPPC interface is 54.5 A2 at 41 degrees C and 54.2 A2 at 30 degrees C. The binding of apo-A1 at 30 degrees C to the emulsion reduces the surface area per DPPC molecule from 54.2 A2 to 50.8 A2.	1,2-Dipalmitoylphosphatidylcholine	218-222	apolipoprotein A1	Homo sapiens	28-34
8770209-11	1996	These changes indicate that apo-A1 increases the amount of ordered gel-like phase on the surface of DPPC emulsions when added at 30 degrees C. From the stoichiometry of the emulsions we calculate that the mean area of DPPC at the triolein/DPPC interface is 54.5 A2 at 41 degrees C and 54.2 A2 at 30 degrees C. The binding of apo-A1 at 30 degrees C to the emulsion reduces the surface area per DPPC molecule from 54.2 A2 to 50.8 A2.	1,2-Dipalmitoylphosphatidylcholine	218-222	apolipoprotein A1	Homo sapiens	325-331
8770209-11	1996	These changes indicate that apo-A1 increases the amount of ordered gel-like phase on the surface of DPPC emulsions when added at 30 degrees C. From the stoichiometry of the emulsions we calculate that the mean area of DPPC at the triolein/DPPC interface is 54.5 A2 at 41 degrees C and 54.2 A2 at 30 degrees C. The binding of apo-A1 at 30 degrees C to the emulsion reduces the surface area per DPPC molecule from 54.2 A2 to 50.8 A2.	1,2-Dipalmitoylphosphatidylcholine	218-222	apolipoprotein A1	Homo sapiens	28-34
8770209-11	1996	These changes indicate that apo-A1 increases the amount of ordered gel-like phase on the surface of DPPC emulsions when added at 30 degrees C. From the stoichiometry of the emulsions we calculate that the mean area of DPPC at the triolein/DPPC interface is 54.5 A2 at 41 degrees C and 54.2 A2 at 30 degrees C. The binding of apo-A1 at 30 degrees C to the emulsion reduces the surface area per DPPC molecule from 54.2 A2 to 50.8 A2.	1,2-Dipalmitoylphosphatidylcholine	218-222	apolipoprotein A1	Homo sapiens	325-331
8770209-12	1996	At 30 degrees apo-A1 binds with high affinity and low capacity to the surface of DPPC emulsions and increases the packing density of the lipid domain to which it binds.	1,2-Dipalmitoylphosphatidylcholine	81-85	apolipoprotein A1	Homo sapiens	14-20
8770209-13	1996	Apo-A1 was also titrated onto DPPC emulsions at 45 degrees C. This temperature is above the gel liquid crystal transition.	1,2-Dipalmitoylphosphatidylcholine	30-34	apolipoprotein A1	Homo sapiens	0-6
8770209-17	1996	This value indicates that apo-A1 binding to a fluid surface like egg yolk phosphatidylcholine or probably DPPC at 45 degrees C is hydrophobic and is consistent with hydrocarbon lipid or protein moities coming together and excluding water.	1,2-Dipalmitoylphosphatidylcholine	106-110	apolipoprotein A1	Homo sapiens	26-32
8599660-1	1995	The interactions of the hydrophobic pulmonary surfactant proteins SP-B and SP-C with 1,2-dipalmitoylphosphatidylcholine in mixed, spread monolayer films have been studied in situ at the air/water interface with the technique of external reflection absorption infrared spectroscopy (IRRAS).	1,2-Dipalmitoylphosphatidylcholine	85-119	surfactant protein C	Homo sapiens	75-79
8527663-6	1995	In contrast to this, a DPPE or a DPPC monolayer on top of a DPPE monolayer gives rise to a rather stable mica-supported bilayer that can be studied by STM.	1,2-Dipalmitoylphosphatidylcholine	33-37	MHC class I polypeptide-related sequence A	Homo sapiens	105-109
9384676-7	1995	MLVs composed of DMPC/DMPG (7:3) and SUVs composed of DPPC/DSPC (1:1) displayed high capacity for binding to caprylated TNF-SAM2.	1,2-Dipalmitoylphosphatidylcholine	54-58	tumor necrosis factor	Homo sapiens	120-123
7640284-3	1995	During compression of SP-A/DPPC films which contained > or = 5 wt % SP-A, properties were displayed which were consistent with the protein being partially squeezed out at surface pressures of about 30 mN/m.	1,2-Dipalmitoylphosphatidylcholine	27-31	surfactant protein A2	Homo sapiens	71-75
7640284-5	1995	During dynamic cyclic compression-expansion of SP-A/DPPC monolayers initially formed at low surface pressures, SP-A enhanced the respreading of the films compressed beyond collapse compared to the respreading after collapse of films containing DPPC alone.	1,2-Dipalmitoylphosphatidylcholine	52-56	surfactant protein A2	Homo sapiens	111-115
7640284-8	1995	Calcium ions in the subphase did not alter the properties of SP-A/DPPC films, whereas they improved the ability of SP-A to mix with DPPG and DPPC/DPPG.	1,2-Dipalmitoylphosphatidylcholine	141-145	surfactant protein A2	Homo sapiens	115-119
7578091-2	1995	Phospholipase A2"s (PLA2) kinetics toward large unilamellar vesicles (LUV) composed of dipalmitoylphosphatidylcholine (DPPC) are anomalous; these is a slow initial phase of catalysis (a lag) which ends abruptly with a sudden increase in the catalytic rate (a burst).	1,2-Dipalmitoylphosphatidylcholine	87-117	phospholipase A2 group IIA	Homo sapiens	0-18
7578091-2	1995	Phospholipase A2"s (PLA2) kinetics toward large unilamellar vesicles (LUV) composed of dipalmitoylphosphatidylcholine (DPPC) are anomalous; these is a slow initial phase of catalysis (a lag) which ends abruptly with a sudden increase in the catalytic rate (a burst).	1,2-Dipalmitoylphosphatidylcholine	87-117	phospholipase A2 group IIA	Homo sapiens	20-24
7578091-2	1995	Phospholipase A2"s (PLA2) kinetics toward large unilamellar vesicles (LUV) composed of dipalmitoylphosphatidylcholine (DPPC) are anomalous; these is a slow initial phase of catalysis (a lag) which ends abruptly with a sudden increase in the catalytic rate (a burst).	1,2-Dipalmitoylphosphatidylcholine	119-123	phospholipase A2 group IIA	Homo sapiens	0-18
7578091-2	1995	Phospholipase A2"s (PLA2) kinetics toward large unilamellar vesicles (LUV) composed of dipalmitoylphosphatidylcholine (DPPC) are anomalous; these is a slow initial phase of catalysis (a lag) which ends abruptly with a sudden increase in the catalytic rate (a burst).	1,2-Dipalmitoylphosphatidylcholine	119-123	phospholipase A2 group IIA	Homo sapiens	20-24
7619843-9	1995	This formula relates the cL beta i values to the free energy of transfer of alcohols from the aqueous sub-phase into the DPPC sub-phase.	1,2-Dipalmitoylphosphatidylcholine	121-125	citramalyl-CoA lyase	Homo sapiens	25-32
7626201-6	1995	The highest inhibition is obtained at a 50:50 molar ratio of PC:PE (iii) By comparing the effects of PC differing in acyl chains, higher inhibition of C(a2+)-ATPase is observed in vesicles containing DPPC:PE and DOPC:PE, while no inhibition in DMPC:PE vesicles (iv) If the transmembrane Ca2+ gradient is in the inverse direction, the enzyme activity of C(a2+)-ATPase is inhibited whenever reconstituted with acidic or neutral phospholipids.	1,2-Dipalmitoylphosphatidylcholine	200-204	dynein axonemal heavy chain 8	Homo sapiens	158-164
7626201-6	1995	The highest inhibition is obtained at a 50:50 molar ratio of PC:PE (iii) By comparing the effects of PC differing in acyl chains, higher inhibition of C(a2+)-ATPase is observed in vesicles containing DPPC:PE and DOPC:PE, while no inhibition in DMPC:PE vesicles (iv) If the transmembrane Ca2+ gradient is in the inverse direction, the enzyme activity of C(a2+)-ATPase is inhibited whenever reconstituted with acidic or neutral phospholipids.	1,2-Dipalmitoylphosphatidylcholine	200-204	dynein axonemal heavy chain 8	Homo sapiens	360-366
7788796-4	1995	In lipid mixtures including DPPC and DPPG, SP-C was associated with shorter chain and unsaturated lipids below the bulk lipid phase transition.	1,2-Dipalmitoylphosphatidylcholine	28-32	surfactant protein C	Homo sapiens	43-47
7744765-7	1995	ApoAI-(1-192) lysed dimyristoyl phosphatidylcholine liposomes slowly compared with apoAI but did form rHDL complexes with palmitoyloleoyl phosphatidylcholine or dipalmitoyl phosphatidylcholine when prepared by the sodium cholate dialysis method.	1,2-Dipalmitoylphosphatidylcholine	161-192	apolipoprotein A1	Homo sapiens	0-5
8555971-0	1995	Preparation and characterization of dipalmitoylphosphatidylcholine liposomes containing interleukin-2.	1,2-Dipalmitoylphosphatidylcholine	36-66	interleukin 2	Homo sapiens	88-101
7696261-0	1995	Interactions of hydrophobic lung surfactant proteins SP-B and SP-C with dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylglycerol bilayers studied by electron spin resonance spectroscopy.	1,2-Dipalmitoylphosphatidylcholine	72-102	surfactant protein B	Homo sapiens	53-57
7696261-0	1995	Interactions of hydrophobic lung surfactant proteins SP-B and SP-C with dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylglycerol bilayers studied by electron spin resonance spectroscopy.	1,2-Dipalmitoylphosphatidylcholine	72-102	surfactant protein C	Homo sapiens	62-66
7696261-1	1995	Hydrophobic surfactant-associated proteins SP-B and SP-C have been isolated from porcine lungs and reconstituted in multilamellar vesicles of dipalmitoylphosphatidylcholine (DPPC) or dipalmitoylphosphatidylglycerol (DPPG) containing different phospholipid spin probes, in order to characterize the lipid--protein interactions by electron spin resonance (ESR) spectroscopy.	1,2-Dipalmitoylphosphatidylcholine	174-178	surfactant protein B	Homo sapiens	43-47
7696261-1	1995	Hydrophobic surfactant-associated proteins SP-B and SP-C have been isolated from porcine lungs and reconstituted in multilamellar vesicles of dipalmitoylphosphatidylcholine (DPPC) or dipalmitoylphosphatidylglycerol (DPPG) containing different phospholipid spin probes, in order to characterize the lipid--protein interactions by electron spin resonance (ESR) spectroscopy.	1,2-Dipalmitoylphosphatidylcholine	174-178	surfactant protein C	Homo sapiens	52-56
7696261-4	1995	The effect was saturated at protein/lipid ratios of 20% and 30% (w/w) for SP-B and SP-C, respectively, in bilayers of DPPC.	1,2-Dipalmitoylphosphatidylcholine	118-122	surfactant protein B	Homo sapiens	74-78
7696261-4	1995	The effect was saturated at protein/lipid ratios of 20% and 30% (w/w) for SP-B and SP-C, respectively, in bilayers of DPPC.	1,2-Dipalmitoylphosphatidylcholine	118-122	surfactant protein C	Homo sapiens	83-87
7696261-5	1995	SP-B and SP-C increased the ordering and decreased the mobility of the lipid acyl chains in both DPPC and DPPG bilayers in the fluid phase, without affecting the gel phase on the convention ESR time scale.	1,2-Dipalmitoylphosphatidylcholine	97-101	surfactant protein B	Homo sapiens	0-4
7696261-5	1995	SP-B and SP-C increased the ordering and decreased the mobility of the lipid acyl chains in both DPPC and DPPG bilayers in the fluid phase, without affecting the gel phase on the convention ESR time scale.	1,2-Dipalmitoylphosphatidylcholine	97-101	surfactant protein C	Homo sapiens	9-13
7696261-7	1995	The selectivity of the interaction of SP-B and SP-C with different phospholipid species was determined from the ESR spectra of spin-labeled phospholipids with different headgroups in host bilayers of either DPPC or DPPG.	1,2-Dipalmitoylphosphatidylcholine	207-211	surfactant protein B	Homo sapiens	38-42
7696261-7	1995	The selectivity of the interaction of SP-B and SP-C with different phospholipid species was determined from the ESR spectra of spin-labeled phospholipids with different headgroups in host bilayers of either DPPC or DPPG.	1,2-Dipalmitoylphosphatidylcholine	207-211	surfactant protein C	Homo sapiens	47-51
7782894-5	1995	Phospholipase A2 activity was assessed in lung, liver, kidney and heart cytosol and microsomes in the presence (5 mmol/L CaCl2) or absence (5 mmol/L EGTA) of calcium with dipalmitoylphosphatidylcholine at pH 6.5.	1,2-Dipalmitoylphosphatidylcholine	171-201	phospholipase A2 group IB	Rattus norvegicus	0-16
7702604-1	1995	We have observed a novel time and dose dependent stimulatory effect of CRP on the hydrolysis of dipalmitoyl phosphatidylcholine (DPPC) into phosphorylcholine (P-choline) and diacylglycerol (DAG).	1,2-Dipalmitoylphosphatidylcholine	96-127	C-reactive protein	Rattus norvegicus	71-74
7702604-1	1995	We have observed a novel time and dose dependent stimulatory effect of CRP on the hydrolysis of dipalmitoyl phosphatidylcholine (DPPC) into phosphorylcholine (P-choline) and diacylglycerol (DAG).	1,2-Dipalmitoylphosphatidylcholine	129-133	C-reactive protein	Rattus norvegicus	71-74
7702604-3	1995	DPPC was also hydrolysed by normal rat serum (contains CRP) but not when serum was depleted of CRP.	1,2-Dipalmitoylphosphatidylcholine	0-4	C-reactive protein	Rattus norvegicus	55-58
7702604-4	1995	There is a requirement of Ca2+ for this unsuspected effect which was observed over a wide range of pH and the effect was markedly increased in temperatures up to 48 degrees C. The hydrolysis of DPPC showed a 3-fold decrease in Km when the assays included rat CRP.	1,2-Dipalmitoylphosphatidylcholine	194-198	C-reactive protein	Rattus norvegicus	259-262
7496727-7	1995	Alum, DPPC/PE and DPPC/PS liposomes also inhibited IFN-gamma/MDP- and IFN-gamma/TNF-alpha-induced NO synthesis.	1,2-Dipalmitoylphosphatidylcholine	6-10	interferon gamma	Mus musculus	51-60
7728935-1	1995	We encapsulated erythropoietin (Epo) in dipalmitoylphosphatidylcholine (DPPC) liposomes with soybean-derived sterols (SS-liposomes) and its glucoside (SG-liposomes) by reverse-phase evaporation vesicle method, and evaluated them by subcutaneous administration in rats.	1,2-Dipalmitoylphosphatidylcholine	40-70	erythropoietin	Rattus norvegicus	16-30
7728935-1	1995	We encapsulated erythropoietin (Epo) in dipalmitoylphosphatidylcholine (DPPC) liposomes with soybean-derived sterols (SS-liposomes) and its glucoside (SG-liposomes) by reverse-phase evaporation vesicle method, and evaluated them by subcutaneous administration in rats.	1,2-Dipalmitoylphosphatidylcholine	40-70	erythropoietin	Rattus norvegicus	32-35
7728935-1	1995	We encapsulated erythropoietin (Epo) in dipalmitoylphosphatidylcholine (DPPC) liposomes with soybean-derived sterols (SS-liposomes) and its glucoside (SG-liposomes) by reverse-phase evaporation vesicle method, and evaluated them by subcutaneous administration in rats.	1,2-Dipalmitoylphosphatidylcholine	72-76	erythropoietin	Rattus norvegicus	16-30
7811738-0	1995	Hydrolysis of DMPC or DPPC by pancreatic phospholipase A2 is slowed down when (perfluoroalkyl) alkanes are incorporated into the liposomal membrane.	1,2-Dipalmitoylphosphatidylcholine	22-26	phospholipase A2 group IB	Homo sapiens	41-57
7811474-8	1995	Both [125I]SP-A and [3H]DPPC were lost exponentially from the total lungs, with half-life values of 6.5 h for SP-A and 12 h for DPPC (P < 0.01).	1,2-Dipalmitoylphosphatidylcholine	24-28	pulmonary surfactant-associated protein A	Oryctolagus cuniculus	110-114
7811474-8	1995	Both [125I]SP-A and [3H]DPPC were lost exponentially from the total lungs, with half-life values of 6.5 h for SP-A and 12 h for DPPC (P < 0.01).	1,2-Dipalmitoylphosphatidylcholine	128-132	pulmonary surfactant-associated protein A	Oryctolagus cuniculus	11-15
7496727-7	1995	Alum, DPPC/PE and DPPC/PS liposomes also inhibited IFN-gamma/MDP- and IFN-gamma/TNF-alpha-induced NO synthesis.	1,2-Dipalmitoylphosphatidylcholine	6-10	interferon gamma	Mus musculus	70-79
7496727-7	1995	Alum, DPPC/PE and DPPC/PS liposomes also inhibited IFN-gamma/MDP- and IFN-gamma/TNF-alpha-induced NO synthesis.	1,2-Dipalmitoylphosphatidylcholine	6-10	tumor necrosis factor	Mus musculus	80-89
7496727-7	1995	Alum, DPPC/PE and DPPC/PS liposomes also inhibited IFN-gamma/MDP- and IFN-gamma/TNF-alpha-induced NO synthesis.	1,2-Dipalmitoylphosphatidylcholine	18-22	interferon gamma	Mus musculus	51-60
7496727-7	1995	Alum, DPPC/PE and DPPC/PS liposomes also inhibited IFN-gamma/MDP- and IFN-gamma/TNF-alpha-induced NO synthesis.	1,2-Dipalmitoylphosphatidylcholine	18-22	interferon gamma	Mus musculus	70-79
7496727-7	1995	Alum, DPPC/PE and DPPC/PS liposomes also inhibited IFN-gamma/MDP- and IFN-gamma/TNF-alpha-induced NO synthesis.	1,2-Dipalmitoylphosphatidylcholine	18-22	tumor necrosis factor	Mus musculus	80-89
7993894-0	1994	Dynamic surface properties of pulmonary surfactant proteins SP-B and SP-C and their mixtures with dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	98-128	surfactant protein C	Homo sapiens	69-73
7993894-4	1994	In this case, SP-B, squeezed out at 50 mN m-1 during compression of the SP-B/DPPC monolayers that contained > or = 10 weight % protein, reinserted in the films during their subsequent expansion.	1,2-Dipalmitoylphosphatidylcholine	77-81	surfactant protein B	Homo sapiens	14-18
7993894-5	1994	Likewise, SP-C-DPPC complexes were reversibly excluded at pi approximately 55 mN m-1 from the SP-C/DPPC films that contained > or = 5 weight % protein.	1,2-Dipalmitoylphosphatidylcholine	15-19	surfactant protein C	Homo sapiens	10-14
7993894-5	1994	Likewise, SP-C-DPPC complexes were reversibly excluded at pi approximately 55 mN m-1 from the SP-C/DPPC films that contained > or = 5 weight % protein.	1,2-Dipalmitoylphosphatidylcholine	15-19	surfactant protein C	Homo sapiens	94-98
7993894-6	1994	Dynamic compression of the mixed protein-lipid films beyond the collapse pressure of DPPC showed that SP-B and SP-C improved the respreading of DPPC in a concentration dependent manner.	1,2-Dipalmitoylphosphatidylcholine	85-89	surfactant protein B	Homo sapiens	102-106
7993894-6	1994	Dynamic compression of the mixed protein-lipid films beyond the collapse pressure of DPPC showed that SP-B and SP-C improved the respreading of DPPC in a concentration dependent manner.	1,2-Dipalmitoylphosphatidylcholine	85-89	surfactant protein C	Homo sapiens	111-115
7993894-6	1994	Dynamic compression of the mixed protein-lipid films beyond the collapse pressure of DPPC showed that SP-B and SP-C improved the respreading of DPPC in a concentration dependent manner.	1,2-Dipalmitoylphosphatidylcholine	144-148	surfactant protein B	Homo sapiens	102-106
7993894-6	1994	Dynamic compression of the mixed protein-lipid films beyond the collapse pressure of DPPC showed that SP-B and SP-C improved the respreading of DPPC in a concentration dependent manner.	1,2-Dipalmitoylphosphatidylcholine	144-148	surfactant protein C	Homo sapiens	111-115
7993894-7	1994	SP-B was more effective in promoting the respreading of DPPC than was SP-C, as indicated by the collapse plateau length ratio criterion.	1,2-Dipalmitoylphosphatidylcholine	56-60	surfactant protein B	Homo sapiens	0-4
7993894-8	1994	The results from this study suggest a possible interfacial role for SP-B and SP-C in lipid replenishment at the alveolar-air interface, through enhancement of the respreading of DPPC collapse phases (SP-B and SP-C) or through reversible removal of phospholipid (SP-C) during dynamic cyclic compression-expansion of the alveolar surface.	1,2-Dipalmitoylphosphatidylcholine	178-182	surfactant protein B	Homo sapiens	68-72
7993894-8	1994	The results from this study suggest a possible interfacial role for SP-B and SP-C in lipid replenishment at the alveolar-air interface, through enhancement of the respreading of DPPC collapse phases (SP-B and SP-C) or through reversible removal of phospholipid (SP-C) during dynamic cyclic compression-expansion of the alveolar surface.	1,2-Dipalmitoylphosphatidylcholine	178-182	surfactant protein C	Homo sapiens	77-81
7993894-8	1994	The results from this study suggest a possible interfacial role for SP-B and SP-C in lipid replenishment at the alveolar-air interface, through enhancement of the respreading of DPPC collapse phases (SP-B and SP-C) or through reversible removal of phospholipid (SP-C) during dynamic cyclic compression-expansion of the alveolar surface.	1,2-Dipalmitoylphosphatidylcholine	178-182	surfactant protein B	Homo sapiens	200-204
7977772-12	1994	Inhibition of plasmin-induced clot lysis was also noted on incorporation of CLSE into clotted plasma and on incorporation of dipalmitoylphosphatidylcholine into fibrin polymers.	1,2-Dipalmitoylphosphatidylcholine	125-155	plasminogen	Bos taurus	14-21
7525589-9	1994	Antibody 1D6 completely blocked the binding of SP-A to dipalmitoylphosphatidylcholine and galactosylceramide and liposome aggregation.	1,2-Dipalmitoylphosphatidylcholine	55-85	surfactant protein A1	Homo sapiens	47-51
7961971-3	1994	SP-A specifically binds to dipalmitoylphosphatidylcholine, the major lipid component of surfactant, and can regulate the secretion and recycling of this lipid by alveolar type II cells.	1,2-Dipalmitoylphosphatidylcholine	27-57	surfactant protein A1	Rattus norvegicus	0-4
7921463-10	1994	And like DPPC, the analogs interacted with isolated SP-B+C and improved in vivo function to levels comparable to LES.	1,2-Dipalmitoylphosphatidylcholine	9-13	pulmonary surfactant-associated protein B	Oryctolagus cuniculus	52-56
7921463-2	1994	Phospholipase A2-resistant analogs of dipalmitoylphosphatidylcholine (DPPC) with surfactant properties might therefore be useful lipid components of treatment surfactants for certain lung injuries.	1,2-Dipalmitoylphosphatidylcholine	38-68	phospholipase A2	Oryctolagus cuniculus	0-16
7921463-2	1994	Phospholipase A2-resistant analogs of dipalmitoylphosphatidylcholine (DPPC) with surfactant properties might therefore be useful lipid components of treatment surfactants for certain lung injuries.	1,2-Dipalmitoylphosphatidylcholine	70-74	phospholipase A2	Oryctolagus cuniculus	0-16
7943260-3	1994	PLA2 was assayed using radiolabeled 1,2-dipalmitoyl phosphatidylcholine (DPPC) in surfactant-like unilamellar liposomes with Ca(2+)-free acidic (pH 4) or 10 mM Ca2+, alkaline (pH 8.5) buffer.	1,2-Dipalmitoylphosphatidylcholine	36-71	phospholipase A2 group IB	Rattus norvegicus	0-4
7943260-3	1994	PLA2 was assayed using radiolabeled 1,2-dipalmitoyl phosphatidylcholine (DPPC) in surfactant-like unilamellar liposomes with Ca(2+)-free acidic (pH 4) or 10 mM Ca2+, alkaline (pH 8.5) buffer.	1,2-Dipalmitoylphosphatidylcholine	73-77	phospholipase A2 group IB	Rattus norvegicus	0-4
8080278-9	1994	In addition, it was found that the ALP activity in DPPC-reconstituted membranes was also inhibited by treatment with ascorbic acid/Fe2+, similar to the case in PC-reconstituted ones.	1,2-Dipalmitoylphosphatidylcholine	51-55	alkaline phosphatase, placental	Homo sapiens	35-38
7923477-1	1994	An abnormal fibrinogen that caused aggregation of red blood cells (RBC) in a patient with gangrene was examined by real-time X-ray diffraction to determine its effects on dipalmitoylphosphatidylcholine (DPPC) and 1-palmitoyl-2-oleoylphosphatidylethanolamine (POPE) phase transitions.	1,2-Dipalmitoylphosphatidylcholine	171-201	fibrinogen beta chain	Homo sapiens	12-22
7943260-7	1994	Binding assay showed binding of 125I-labeled SP-A to DPPC but not to POPC, indicating that removal of substrate was not the mechanism for inhibition of the enzyme by SP-A.	1,2-Dipalmitoylphosphatidylcholine	53-57	surfactant protein A1	Rattus norvegicus	45-49
7943260-10	1994	The presence of SP-A in liposomes stimulated the uptake of DPPC by isolated granular pneumocytes in primary culture but significantly inhibited its degradation.	1,2-Dipalmitoylphosphatidylcholine	59-63	surfactant protein A1	Rattus norvegicus	16-20
7923477-1	1994	An abnormal fibrinogen that caused aggregation of red blood cells (RBC) in a patient with gangrene was examined by real-time X-ray diffraction to determine its effects on dipalmitoylphosphatidylcholine (DPPC) and 1-palmitoyl-2-oleoylphosphatidylethanolamine (POPE) phase transitions.	1,2-Dipalmitoylphosphatidylcholine	203-207	fibrinogen beta chain	Homo sapiens	12-22
8280055-6	1993	In addition, we demonstrated a shielding of the tryptophan fluorescence from quenching by acrylamide on interaction of porcine SP-A with DPPC, DPPG or LPC.	1,2-Dipalmitoylphosphatidylcholine	137-141	surfactant protein A1	Homo sapiens	127-131
8038386-2	1994	The interaction of the hydrophobic pulmonary surfactant protein SP-C with dipalmitoylphosphatidylcholine (DPPC), dipalmitoylphosphatidylglycerol (DPPG) and DPPC:DPPG (7:3, mol:mol) in spread monolayers at the air-water interface has been studied.	1,2-Dipalmitoylphosphatidylcholine	74-104	surfactant protein C	Homo sapiens	64-68
8038386-2	1994	The interaction of the hydrophobic pulmonary surfactant protein SP-C with dipalmitoylphosphatidylcholine (DPPC), dipalmitoylphosphatidylglycerol (DPPG) and DPPC:DPPG (7:3, mol:mol) in spread monolayers at the air-water interface has been studied.	1,2-Dipalmitoylphosphatidylcholine	106-110	surfactant protein C	Homo sapiens	64-68
8038386-2	1994	The interaction of the hydrophobic pulmonary surfactant protein SP-C with dipalmitoylphosphatidylcholine (DPPC), dipalmitoylphosphatidylglycerol (DPPG) and DPPC:DPPG (7:3, mol:mol) in spread monolayers at the air-water interface has been studied.	1,2-Dipalmitoylphosphatidylcholine	156-160	surfactant protein C	Homo sapiens	64-68
8038387-9	1994	This led to a conclusion that there was independent behavior of SP-B and SP-C in (SP-B:SP-C)/DPPC monolayers.	1,2-Dipalmitoylphosphatidylcholine	93-97	surfactant protein B	Homo sapiens	64-68
8038387-9	1994	This led to a conclusion that there was independent behavior of SP-B and SP-C in (SP-B:SP-C)/DPPC monolayers.	1,2-Dipalmitoylphosphatidylcholine	93-97	surfactant protein C	Homo sapiens	73-77
8038387-9	1994	This led to a conclusion that there was independent behavior of SP-B and SP-C in (SP-B:SP-C)/DPPC monolayers.	1,2-Dipalmitoylphosphatidylcholine	93-97	surfactant protein B	Homo sapiens	82-86
8110807-1	1994	The modulation by gangliosides GM1 and GD1a, and sulfatide (Sulf) of the activity of porcine pancreatic phospholipase A2 was studied with small unilamellar vesicles of dipalmitoylphosphatidylcholine (L-dpPC) and lipid monolayers of dilauroylphosphatidylcholine (L-dlPC).	1,2-Dipalmitoylphosphatidylcholine	168-198	phospholipase A2 group IB	Homo sapiens	104-120
8038385-5	1994	Calculated analyses of the monolayer compositions as a function of surface pressure indicated that nearly pure SP-B, associated with small amounts of phospholipid (2-3 lipid molecules per SP-B dimer), was lost from SP-B/DPPC, SP-B/DPPG, and SP-B/(DPPC:DPPG) films at surface pressures higher than 40-45 mN.m-1.	1,2-Dipalmitoylphosphatidylcholine	220-224	surfactant protein B	Homo sapiens	111-115
8038385-5	1994	Calculated analyses of the monolayer compositions as a function of surface pressure indicated that nearly pure SP-B, associated with small amounts of phospholipid (2-3 lipid molecules per SP-B dimer), was lost from SP-B/DPPC, SP-B/DPPG, and SP-B/(DPPC:DPPG) films at surface pressures higher than 40-45 mN.m-1.	1,2-Dipalmitoylphosphatidylcholine	247-251	surfactant protein B	Homo sapiens	111-115
8038385-6	1994	The results are consistent with a low effectiveness of SP-B in removing saturated phospholipids, DPPC or DPPG, from the spread SP-B/phospholipid films.	1,2-Dipalmitoylphosphatidylcholine	97-101	surfactant protein B	Homo sapiens	55-59
8280055-8	1993	In the case of human SP-A, shielding was only observed on interaction with DPPC.	1,2-Dipalmitoylphosphatidylcholine	75-79	surfactant protein A1	Homo sapiens	21-25
8280055-9	1993	From the intrinsic fluorescence measurements as well as from the quenching experiments, we concluded that the interaction of some phospholipid vesicles with SP-A produces a conformational change on the protein molecule and that the interaction of SP-A with DPPC is stronger than with other phospholipids.	1,2-Dipalmitoylphosphatidylcholine	257-261	surfactant protein A1	Homo sapiens	247-251
8280055-11	1993	Physiological ionic strength was found to be required for the interaction of SP-A with negatively charged vesicles of either DPPG or DPPC/DPPG (7:3, w/w).	1,2-Dipalmitoylphosphatidylcholine	133-137	surfactant protein A1	Homo sapiens	77-81
8280055-13	1993	The increase in intrinsic fluorescence of SP-A in the presence of DPPC vesicles was much stronger when the vesicles were in the gel state than when they were in the liquid-crystalline state.	1,2-Dipalmitoylphosphatidylcholine	66-70	surfactant protein A1	Homo sapiens	42-46
8368329-2	1993	SP-A enhanced the uptake of liposomes containing dipalmitoylphosphatidylcholine (DPPC), 1-palmitoyl-2-linoleoyl phosphatidylcholine (PLPC), or 1,2-dihexadecyl-sn-glycero-3-phosphocholine (DPPC-ether), a diether analogue of DPPC, but about twice as much DPPC was taken up by type II cells as PLPC or DPPC-ether.	1,2-Dipalmitoylphosphatidylcholine	49-79	surfactant protein A1	Homo sapiens	0-4
8277518-4	1993	Loss of cathepsin B activity was completely prevented by the pretreatment of quartz with the surfactant component dipalmitoyl lecithin.	1,2-Dipalmitoylphosphatidylcholine	114-134	cathepsin B	Bos taurus	8-19
8368329-2	1993	SP-A enhanced the uptake of liposomes containing dipalmitoylphosphatidylcholine (DPPC), 1-palmitoyl-2-linoleoyl phosphatidylcholine (PLPC), or 1,2-dihexadecyl-sn-glycero-3-phosphocholine (DPPC-ether), a diether analogue of DPPC, but about twice as much DPPC was taken up by type II cells as PLPC or DPPC-ether.	1,2-Dipalmitoylphosphatidylcholine	81-85	surfactant protein A1	Homo sapiens	0-4
8368329-2	1993	SP-A enhanced the uptake of liposomes containing dipalmitoylphosphatidylcholine (DPPC), 1-palmitoyl-2-linoleoyl phosphatidylcholine (PLPC), or 1,2-dihexadecyl-sn-glycero-3-phosphocholine (DPPC-ether), a diether analogue of DPPC, but about twice as much DPPC was taken up by type II cells as PLPC or DPPC-ether.	1,2-Dipalmitoylphosphatidylcholine	188-192	surfactant protein A1	Homo sapiens	0-4
8368329-2	1993	SP-A enhanced the uptake of liposomes containing dipalmitoylphosphatidylcholine (DPPC), 1-palmitoyl-2-linoleoyl phosphatidylcholine (PLPC), or 1,2-dihexadecyl-sn-glycero-3-phosphocholine (DPPC-ether), a diether analogue of DPPC, but about twice as much DPPC was taken up by type II cells as PLPC or DPPC-ether.	1,2-Dipalmitoylphosphatidylcholine	188-192	surfactant protein A1	Homo sapiens	0-4
8368329-3	1993	When subcellular distribution was analyzed, 51.3 +/- 2.9% (mean +/- SD, n = 3) of cell-associated radiolabeled DPPC was recovered in the lamellar body-rich fraction in the presence of SP-A, whereas only 19.3 +/- 1.9% (mean +/- SD, n = 3) was found to this fraction in the absence of SP-A.	1,2-Dipalmitoylphosphatidylcholine	111-115	surfactant protein A1	Homo sapiens	184-188
8368329-7	1993	Subcellular fractionations of type II cells with radiolabeled SP-A and DPPC revealed that the sedimentation characteristics of cell-associated SP-A are different from those of DPPC, although a small broad peak of radiolabeled SP-A was found in the lamellar body fraction.	1,2-Dipalmitoylphosphatidylcholine	71-75	surfactant protein A1	Homo sapiens	143-147
8368329-7	1993	Subcellular fractionations of type II cells with radiolabeled SP-A and DPPC revealed that the sedimentation characteristics of cell-associated SP-A are different from those of DPPC, although a small broad peak of radiolabeled SP-A was found in the lamellar body fraction.	1,2-Dipalmitoylphosphatidylcholine	71-75	surfactant protein A1	Homo sapiens	143-147
8406689-4	1993	The cat-PLA2 was measured by radioactive dipalmitoyl phosphatidylcholine as substrate.	1,2-Dipalmitoylphosphatidylcholine	41-72	phospholipase A2 group IIA	Homo sapiens	8-12
8323940-3	1993	Inclusion of GM1 (6 mol%) endowed DPPC/DSPC liposomes with prolonged circulation ability, resulting in increased blood levels of liposomes and decreased reticuloendothelial system uptake over 6 h after injection.	1,2-Dipalmitoylphosphatidylcholine	34-38	coenzyme Q10A	Mus musculus	13-16
8323946-10	1993	Apo A-IV helicity increased for the protein bound to DMPC or DPPC but the increase was more pronounced for the apo A-IV/DMPC particles.	1,2-Dipalmitoylphosphatidylcholine	61-65	apolipoprotein A4	Homo sapiens	0-8
8323965-12	1993	The alpha-helical content of SP-C in micelles of LPC and vesicles of DPPC, 60 and 70%, respectively, was calculated to be higher than the alpha-helical content of the protein dissolved in any aqueous organic solvent.	1,2-Dipalmitoylphosphatidylcholine	69-73	surfactant protein C	Homo sapiens	29-33
1445903-2	1992	The 13C NMR spectra of both DPG and DPPC specifically 13C-labeled at the sn-2 chain carbonyl exhibit a single narrow resonance (approximately 2 ppm) in liquid-crystalline egg PC bilayers.	1,2-Dipalmitoylphosphatidylcholine	36-40	solute carrier family 38 member 5	Homo sapiens	73-77
8482637-6	1993	The radioactivity of both phospholipids and SP-C (expressed as disintegrations per minute per microgram phospholipid) in lamellar body fractions increased up to 4 h postinstillation and began to decline after approximately 4 h. The results of this study suggest that SP-C and dipalmitoylphosphatidylcholine are taken up promptly from the alveolar air space and are incorporated into lamellar bodies with time courses that do not differ greatly.	1,2-Dipalmitoylphosphatidylcholine	276-306	surfactant protein C	Rattus norvegicus	44-48
1306239-6	1992	We revealed that SP-A binds specifically to dipalmitoylphosphatidylcholine and galactose-ceramide and asialo GM2, while SP-D binds specifically to phosphatidylinositol and glucose-ceramide.	1,2-Dipalmitoylphosphatidylcholine	44-74	surfactant protein A1	Homo sapiens	17-21
8504138-5	1993	Based on competition between bovine serum albumin and the vesicles for the lysophospholipid, we estimated the partition coefficient to be about 5.10(-7) for palmitoyl lipids at 39 degrees C and about 9.10(-7) for myristoyl lipids at 22 degrees C. These values were able to rationalize the behavior of the lag time with dipalmitoylphosphatidylcholine vesicles, but they were unable to predict the behavior with dimyristoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	319-349	albumin	Homo sapiens	36-49
8476867-1	1993	Synthetic human pulmonary surfactant-associated protein SP-B has been interacted with chain-perdeuterated dipalmitoylphosphatidylcholine (DPPC-d62) in aqueous dispersions, and the dispersions were investigated by magnetic resonance spectroscopy.	1,2-Dipalmitoylphosphatidylcholine	106-136	surfactant protein B	Homo sapiens	56-60
8422370-2	1993	The presence of either SP-B or SP-C in dipalmitoylphosphatidylcholine (DPPC) or dipalmitoylphosphatidylglycerol (DPPG) multilamellar vesicles broadened the DSC thermogram and reduced the enthalpy of transition in a concentration-dependent manner.	1,2-Dipalmitoylphosphatidylcholine	39-69	surfactant protein B	Homo sapiens	23-27
8422370-2	1993	The presence of either SP-B or SP-C in dipalmitoylphosphatidylcholine (DPPC) or dipalmitoylphosphatidylglycerol (DPPG) multilamellar vesicles broadened the DSC thermogram and reduced the enthalpy of transition in a concentration-dependent manner.	1,2-Dipalmitoylphosphatidylcholine	39-69	surfactant protein C	Homo sapiens	31-35
8422370-2	1993	The presence of either SP-B or SP-C in dipalmitoylphosphatidylcholine (DPPC) or dipalmitoylphosphatidylglycerol (DPPG) multilamellar vesicles broadened the DSC thermogram and reduced the enthalpy of transition in a concentration-dependent manner.	1,2-Dipalmitoylphosphatidylcholine	71-75	surfactant protein B	Homo sapiens	23-27
8422370-2	1993	The presence of either SP-B or SP-C in dipalmitoylphosphatidylcholine (DPPC) or dipalmitoylphosphatidylglycerol (DPPG) multilamellar vesicles broadened the DSC thermogram and reduced the enthalpy of transition in a concentration-dependent manner.	1,2-Dipalmitoylphosphatidylcholine	71-75	surfactant protein C	Homo sapiens	31-35
1384706-6	1992	The leakage experiment of 5,6-carboxyfluorescein encapsulated in DPPC liposomes showed that the activities of melittin 1-22 and melittin-lac in membrane lysis were much lower than melittin.	1,2-Dipalmitoylphosphatidylcholine	65-69	lactase	Homo sapiens	137-140
1333208-6	1992	On the other hand, pretreatment of rats with DPPC/alpha-tocopherol liposomes 24 hr prior to paraquat challenge resulted in a significant increase in pulmonary alpha-tocopherol concentrations and antagonized paraquat-induced changes in lipid peroxidation, GSH/GSSG ratio, lung ACE activity and cytochrome P450 concentrations.	1,2-Dipalmitoylphosphatidylcholine	45-49	angiotensin I converting enzyme	Rattus norvegicus	276-279
1731593-7	1992	Addition of SP-B,C to Exosurf improved this minimum to 1 mN/m and approached the behavior of mixtures of synthetic DPPC with SP-B,C.	1,2-Dipalmitoylphosphatidylcholine	115-119	surfactant protein B	Rattus norvegicus	12-16
1525175-4	1992	Lung catalase activity was temporally associated with the late gestational increase in the fractional content of lung DPPC (r = 0.79, P less than 0.01).	1,2-Dipalmitoylphosphatidylcholine	118-122	catalase	Homo sapiens	5-13
1606172-3	1992	The Wilhelmy surface plate technique was utilized to investigate the interaction between pure SP-B in the bulk phase (0.9% NaCl/1.5 mM CaCl2) and preformed DPPC or phosphatidylglycerol (PG) monolayers.	1,2-Dipalmitoylphosphatidylcholine	156-160	surfactant protein B	Homo sapiens	94-98
1606172-8	1992	DPPC/POPG/SP-B (7:3:1%) was found to be more surface active than pure POPG plus 1% SP-B in the presence of calcium.	1,2-Dipalmitoylphosphatidylcholine	0-4	surfactant protein B	Homo sapiens	10-14
1606172-8	1992	DPPC/POPG/SP-B (7:3:1%) was found to be more surface active than pure POPG plus 1% SP-B in the presence of calcium.	1,2-Dipalmitoylphosphatidylcholine	0-4	surfactant protein B	Homo sapiens	83-87
1606172-9	1992	Injection of SP-B into the bulk phase promoted the adsorption of DPPC/POPG liposomes to a greater extent than POPG liposomes.	1,2-Dipalmitoylphosphatidylcholine	65-69	surfactant protein B	Homo sapiens	13-17
1606176-11	1992	Emulsions containing 20% of DPPC in POPC were metabolized similarly to 100% POPC, but 40% or more of DPPC progressively slowed the removal from plasma of both TO and CO. With 100% DPPC clearance was characterized by a rapid initial removal of about 30% of the injected material, followed by a second phase when removal was negligible, suggesting lack of hydrolysis of triacylglycerols by lipoprotein lipase.	1,2-Dipalmitoylphosphatidylcholine	101-105	lipoprotein lipase	Rattus norvegicus	388-406
1606176-11	1992	Emulsions containing 20% of DPPC in POPC were metabolized similarly to 100% POPC, but 40% or more of DPPC progressively slowed the removal from plasma of both TO and CO. With 100% DPPC clearance was characterized by a rapid initial removal of about 30% of the injected material, followed by a second phase when removal was negligible, suggesting lack of hydrolysis of triacylglycerols by lipoprotein lipase.	1,2-Dipalmitoylphosphatidylcholine	101-105	lipoprotein lipase	Rattus norvegicus	388-406
1616057-2	1992	To determine possible mechanisms of tubular myelin formation, we studied the effects of purified surfactant proteins (SP-A, SP-B, and SP-C) on large unilamellar dipalmitoylphosphatidylcholine-egg phosphatidylglycerol (7/3; wt/wt) liposomes.	1,2-Dipalmitoylphosphatidylcholine	161-191	surfactant protein C	Homo sapiens	134-138
1586669-4	1992	The enrichment of plasma membranes with dipalmitoylphosphatidylcholine and sphingomyelin led to decrease in protein kinase A and C activities.	1,2-Dipalmitoylphosphatidylcholine	40-70	protein kinase cAMP-activated catalytic subunit alpha	Rattus norvegicus	108-124
1486663-5	1992	Fourier transform-infrared spectroscopy (FT-IR) was utilized to determine the secondary structures of [SP-C]2 in DPPC films.	1,2-Dipalmitoylphosphatidylcholine	113-117	surfactant protein C	Bos taurus	103-107
1420867-0	1992	Pulmonary surfactant protein SP-C causes packing rearrangements of dipalmitoylphosphatidylcholine in spread monolayers.	1,2-Dipalmitoylphosphatidylcholine	67-97	surfactant protein C	Homo sapiens	29-33
1420867-1	1992	The hydrophobic pulmonary surfactant protein SP-C has been isolated from porcine lung surfactant, and it has been incorporated into monolayers of dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	146-176	surfactant protein C	Homo sapiens	45-49
1420867-1	1992	The hydrophobic pulmonary surfactant protein SP-C has been isolated from porcine lung surfactant, and it has been incorporated into monolayers of dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	178-182	surfactant protein C	Homo sapiens	45-49
1420867-3	1992	SP-C altered the packing arrangements of DPPC in the monolayer, causing the production of many more, smaller condensed lipid domains in its presence than in its absence.	1,2-Dipalmitoylphosphatidylcholine	41-45	surfactant protein C	Homo sapiens	0-4
1420869-1	1992	Fluorescence photobleaching recovery with total internal reflection illumination (TIR-FPR) has been used to measure the dissociation kinetics of a fluorescein-labeled anti-dinitrophenyl monoclonal Fab specifically bound to supported monolayers composed of a mixture of dipalmitoylphosphatidylcholine and dinitrophenyl-conjugated dipalmitoylphosphatidylethanolamine.	1,2-Dipalmitoylphosphatidylcholine	269-299	FA complementation group B	Homo sapiens	197-200
1616924-1	1992	Lipid-protein interactions of pulmonary surfactant-associated protein SP-C in model DPPC/DPPG and DPPC/DPPG/eggPC vesicles were studied using steady-state and time-resolved fluorescence measurements of two fluorescent phospholipid probes, NBD-PC and NBD-PG.	1,2-Dipalmitoylphosphatidylcholine	84-88	surfactant protein C	Homo sapiens	70-74
1616924-1	1992	Lipid-protein interactions of pulmonary surfactant-associated protein SP-C in model DPPC/DPPG and DPPC/DPPG/eggPC vesicles were studied using steady-state and time-resolved fluorescence measurements of two fluorescent phospholipid probes, NBD-PC and NBD-PG.	1,2-Dipalmitoylphosphatidylcholine	98-102	surfactant protein C	Homo sapiens	70-74
1616924-4	1992	Time-resolved measurements, as well as steady-state intensity measurements indicate that incorporation of SP-C into DPPC/DPPG or DPPC/DPPG/eggPC vesicles results in a increase in the fraction of the long-lifetime species of NBD-PC.	1,2-Dipalmitoylphosphatidylcholine	116-120	surfactant protein C	Homo sapiens	106-110
1581331-11	1992	Introduction of fluorescence-labeled phospholipase A2 underneath these mixed domains results in rapid binding of the protein to the domains without visible hydrolytic activity, regardless of whether the L-form or the D-form of the DPPC were used.	1,2-Dipalmitoylphosphatidylcholine	231-235	phospholipase A2 group IB	Homo sapiens	37-53
1581331-12	1992	In binary mixtures, only those with DPPC/palmitic acid show formation of phase-separated areas which can be specifically targeted by phospholipase A2 leading to a rapid formation (within 2 min) of protein domains.	1,2-Dipalmitoylphosphatidylcholine	36-40	phospholipase A2 group IB	Homo sapiens	133-149
1557930-2	1992	Dipalmitoylphosphatidylcholine/dimyristolylphosphatidylglycerol liposomes (10:1 molar ratio; 1 mumol) containing BSA, CEA or sIgG induced significant levels of IgG antibodies after one injection, and enhanced the proportion of IgG2a/2b to IgG1 on subsequent boost injection.	1,2-Dipalmitoylphosphatidylcholine	0-30	CEA cell adhesion molecule 3	Homo sapiens	118-121
1854738-4	1991	A large [14C]carbonyl carbon isotope effect of 1.12 +/- 0.02 was measured for the cobra venom PLA2-catalyzed hydrolysis of dipalmitoylphosphatidylcholine in Triton X-100.	1,2-Dipalmitoylphosphatidylcholine	123-153	phospholipase A2 group IB	Homo sapiens	94-98
1911771-1	1991	SP-C, a highly hydrophobic, 3.7-kDa protein constituent of lung surfactant, has been isolated from bovine lung lavage, purified, and reconstituted into binary lipid mixtures of 1,2-dipalmitoyl-phosphatidylcholine (DPPC) and 1,2-dipalmitoylphosphatidylglycerol (DPPG).	1,2-Dipalmitoylphosphatidylcholine	177-212	surfactant protein C	Bos taurus	0-4
1911771-1	1991	SP-C, a highly hydrophobic, 3.7-kDa protein constituent of lung surfactant, has been isolated from bovine lung lavage, purified, and reconstituted into binary lipid mixtures of 1,2-dipalmitoyl-phosphatidylcholine (DPPC) and 1,2-dipalmitoylphosphatidylglycerol (DPPG).	1,2-Dipalmitoylphosphatidylcholine	214-218	surfactant protein C	Bos taurus	0-4
1656453-2	1991	Phospholipid biradicals provide the electron spin resonance spectroscopic resolution of two immiscible fluid phases in the dipalmitoylphosphatidylcholine-cholesterol system.	1,2-Dipalmitoylphosphatidylcholine	123-153	spindlin 1	Homo sapiens	45-49
1718450-6	1991	Monoclonal antibody 3D12F11 (subclass IgG1) showed a high affinity for the apoE (Kd = 3.5 +/- 0.5 nM) without any effect on the apoprotein binding to heparin-Sepharose and apoE-induced destruction of dipalmitoylphosphatidylcholine liposomes.	1,2-Dipalmitoylphosphatidylcholine	200-230	apolipoprotein E	Homo sapiens	75-79
2054776-10	1991	The biological activity of dipalmitoylphosphatidylcholine-small unilamellar vesicle-C8-TNF was found to be comparable to that of the nonliposomal C8-TNF.	1,2-Dipalmitoylphosphatidylcholine	27-57	tumor necrosis factor	Homo sapiens	87-90
1934195-7	1991	The presence of physiological concentrations SP-B/C reduced the width of the anisotropy of DPPC below but had no effect on lipids above the main phase transition temperature.	1,2-Dipalmitoylphosphatidylcholine	91-95	surfactant protein B	Bos taurus	45-49
2223804-5	1990	We found that in vesicles composed of 30% L-alpha-PS and 70% DPPC, the PLP boundary layer contained about 18 motionally restricted phospholipids, almost exclusively L-alpha-PS.	1,2-Dipalmitoylphosphatidylcholine	61-65	proteolipid protein 1	Homo sapiens	71-74
1901346-2	1991	The apoA-I samples were reconstituted with palmitoyloleoyl phosphatidylcholine (POPC) or dipalmitoyl phosphatidylcholine (DPPC), and small amounts of cholesterol, into discoidal high density lipoprotein (HDL) complexes in order to examine their lipid binding and structural properties as well as their ability to activate lecithin:cholesterol acyltransferase (LCAT).	1,2-Dipalmitoylphosphatidylcholine	89-120	apolipoprotein A1	Homo sapiens	4-10
2223804-7	1990	In mixtures of DMPG and DPPC, the selectivity of PLP for the acidic phospholipid DMPG was maintained, but was lower than that observed for L-alpha-PS.	1,2-Dipalmitoylphosphatidylcholine	24-28	proteolipid protein 1	Homo sapiens	49-52
2334729-4	1990	DPPC solid phase domains were specifically targeted by phospholipase A2 and were observed to be hydrolyzed in a manner consistent with localized packing density differences.	1,2-Dipalmitoylphosphatidylcholine	0-4	phospholipase A2 group IB	Homo sapiens	55-71
2115332-0	1990	Dipalmitoylphosphatidylcholine (L-alpha-lecithin) stimulates phospholipase A2 activity in human amnion.	1,2-Dipalmitoylphosphatidylcholine	0-30	phospholipase A2 group IB	Homo sapiens	61-77
2115332-2	1990	Only PLA2 activity was increased by DPPC, suggesting that lecithin, the major surfactant component, increases the PGE production of the amniotic membrane by activating PLA2.	1,2-Dipalmitoylphosphatidylcholine	36-40	phospholipase A2 group IB	Homo sapiens	5-9
2115332-2	1990	Only PLA2 activity was increased by DPPC, suggesting that lecithin, the major surfactant component, increases the PGE production of the amniotic membrane by activating PLA2.	1,2-Dipalmitoylphosphatidylcholine	36-40	phospholipase A2 group IB	Homo sapiens	168-172
2378907-10	1990	Reconstituted surfactant preparations containing SP-B and dipalmitoylphosphatidylcholine plus dioleoylphosphatidylglycerol were capable of reducing the surface tension to near zero values at minimum bubble radius while the reconstitutes with SP-C only lowered the surface tension to approx.	1,2-Dipalmitoylphosphatidylcholine	58-88	surfactant protein C	Bos taurus	242-246
2378907-14	1990	In addition, SP-B appears to facilitate the squeeze-out of unsaturated phospholipids leading to an enrichment of dipalmitoylphosphatidylcholine in the monolayer.	1,2-Dipalmitoylphosphatidylcholine	113-143	surfactant protein B	Bos taurus	13-17
2380172-2	1990	Cholesterol-dependent enhancement of self-quenching also occurs when N-(lissamine-rhodamine-B-sulfonyl)dioleoylphosphatidylethanolamine is substituted for C18-Rh and resembles that in dipalmitoylphosphatidylcholine vesicles below, as opposed to above, the phase transition.	1,2-Dipalmitoylphosphatidylcholine	184-214	Bardet-Biedl syndrome 9	Homo sapiens	155-158
2337412-2	1990	Utilizing classical Michaelis-Menten kinetics, apparent Km and Vmax values for HSF-PLA2 of 1.34 mM and 0.47 mumol [3H]palmitic acid released/min/mg protein were obtained using dipalmitoylphosphatidylcholine (DPPC) as the substrate, and 38.0 microM and 18.8 mumol [3H]arachidonic acid released/min/mg protein with Escherichia coli as a natural substrate.	1,2-Dipalmitoylphosphatidylcholine	176-206	interleukin 6	Homo sapiens	79-82
2337412-2	1990	Utilizing classical Michaelis-Menten kinetics, apparent Km and Vmax values for HSF-PLA2 of 1.34 mM and 0.47 mumol [3H]palmitic acid released/min/mg protein were obtained using dipalmitoylphosphatidylcholine (DPPC) as the substrate, and 38.0 microM and 18.8 mumol [3H]arachidonic acid released/min/mg protein with Escherichia coli as a natural substrate.	1,2-Dipalmitoylphosphatidylcholine	176-206	phospholipase A2 group IIA	Homo sapiens	83-87
2337412-2	1990	Utilizing classical Michaelis-Menten kinetics, apparent Km and Vmax values for HSF-PLA2 of 1.34 mM and 0.47 mumol [3H]palmitic acid released/min/mg protein were obtained using dipalmitoylphosphatidylcholine (DPPC) as the substrate, and 38.0 microM and 18.8 mumol [3H]arachidonic acid released/min/mg protein with Escherichia coli as a natural substrate.	1,2-Dipalmitoylphosphatidylcholine	208-212	interleukin 6	Homo sapiens	79-82
2337412-2	1990	Utilizing classical Michaelis-Menten kinetics, apparent Km and Vmax values for HSF-PLA2 of 1.34 mM and 0.47 mumol [3H]palmitic acid released/min/mg protein were obtained using dipalmitoylphosphatidylcholine (DPPC) as the substrate, and 38.0 microM and 18.8 mumol [3H]arachidonic acid released/min/mg protein with Escherichia coli as a natural substrate.	1,2-Dipalmitoylphosphatidylcholine	208-212	phospholipase A2 group IIA	Homo sapiens	83-87
2337412-4	1990	Inhibition of HSF-PLA2 by MLD was concentration and time dependent with IC50 values of 0.2 and 0.02 microM for DPPC and E. coli respectively.	1,2-Dipalmitoylphosphatidylcholine	111-115	interleukin 6	Homo sapiens	14-17
2337412-4	1990	Inhibition of HSF-PLA2 by MLD was concentration and time dependent with IC50 values of 0.2 and 0.02 microM for DPPC and E. coli respectively.	1,2-Dipalmitoylphosphatidylcholine	111-115	phospholipase A2 group IIA	Homo sapiens	18-22
2344355-1	1990	The effects of tumour promoters, namely phorbol esters and teleocidin, on the activity of porcine pancreatic phospholipase A2 (PLA2) was investigated by using a system of small unilamellar vesicles composed of dipalmitoyl-phosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	210-241	phospholipase A2 group IB	Homo sapiens	109-125
2344355-1	1990	The effects of tumour promoters, namely phorbol esters and teleocidin, on the activity of porcine pancreatic phospholipase A2 (PLA2) was investigated by using a system of small unilamellar vesicles composed of dipalmitoyl-phosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	210-241	phospholipase A2 group IB	Homo sapiens	127-131
2344355-1	1990	The effects of tumour promoters, namely phorbol esters and teleocidin, on the activity of porcine pancreatic phospholipase A2 (PLA2) was investigated by using a system of small unilamellar vesicles composed of dipalmitoyl-phosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	243-247	phospholipase A2 group IB	Homo sapiens	109-125
2344355-1	1990	The effects of tumour promoters, namely phorbol esters and teleocidin, on the activity of porcine pancreatic phospholipase A2 (PLA2) was investigated by using a system of small unilamellar vesicles composed of dipalmitoyl-phosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	243-247	phospholipase A2 group IB	Homo sapiens	127-131
2344355-3	1990	The addition of PLA2 to Quin 2/DPPC vesicles increased the fluorescence intensity of Quin 2.	1,2-Dipalmitoylphosphatidylcholine	31-35	phospholipase A2 group IB	Homo sapiens	16-20
34571084-6	2021	Moreover, IR780/DPPC/BMS initiated gel-liquid crystal phase transition under laser irradiation, accelerating the disintegration of lipid bilayer structure and leading to the responsive release of BMS, which would reverse the tumor immunosuppression state by blocking PD-1/PD-L1 pathway for a long term.	1,2-Dipalmitoylphosphatidylcholine	16-20	spermatogenesis associated 2	Homo sapiens	267-271
2156930-6	1990	The results demonstrate that LPS stimulates phospholipase A2 activity and the hydrolysis of both 1,2-dipalmitoyl phosphatidylcholine and 1-steroyl 2-arachidonoyl phosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	97-132	interferon regulatory factor 6	Homo sapiens	29-32
2156930-6	1990	The results demonstrate that LPS stimulates phospholipase A2 activity and the hydrolysis of both 1,2-dipalmitoyl phosphatidylcholine and 1-steroyl 2-arachidonoyl phosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	97-132	phospholipase A2 group IB	Homo sapiens	44-60
34954575-1	2022	The influence of cholesterol (CHO), bovine serum albumin (BSA) and lactoferrin (LF), on the phase transition temperature (Tm) and structure of DPPC liposomes during in vitro digestion was investigated using Dynamic Laser Scattering (DLS) and Fourier Transform Infrared Spectroscopy technologies (FTIR).	1,2-Dipalmitoylphosphatidylcholine	143-147	albumin	Homo sapiens	43-56
34666082-4	2022	The results indicated that the surface pressure-area (pi-A) isotherms of DPPC monolayers shifted toward lower molecular areas and the compression modulus (CS-1) reduced in the presence of DEPM.	1,2-Dipalmitoylphosphatidylcholine	73-77	chorionic somatomammotropin hormone 1	Homo sapiens	155-159
34662568-3	2022	For chain segments at the beginning of the hydrocarbon region, (alpha2)-values are markedly restricted and temperature independent in DPPC with the lowest water content, whereas they increase with temperature in the low and fully hydrated bilayers, particularly at the highest temperatures.	1,2-Dipalmitoylphosphatidylcholine	134-138	glycoprotein hormone subunit alpha 2	Homo sapiens	64-70
34571084-6	2021	Moreover, IR780/DPPC/BMS initiated gel-liquid crystal phase transition under laser irradiation, accelerating the disintegration of lipid bilayer structure and leading to the responsive release of BMS, which would reverse the tumor immunosuppression state by blocking PD-1/PD-L1 pathway for a long term.	1,2-Dipalmitoylphosphatidylcholine	16-20	CD274 molecule	Homo sapiens	272-277
34673168-5	2021	Herein, we produced optimized Hyp thermosensitive liposomes (Hyp-TSL), which are self-assembled from DPPC, DSPC, DSPE-PEG2000.	1,2-Dipalmitoylphosphatidylcholine	101-105	TSL	Homo sapiens	65-68
34482548-8	2021	Exogenous C16 ceramide, dipalmitoyl-phosphatidylcholine, and dipalmitoyl-phosphatidylethanolamine were sufficient to significantly induce Npy expression.	1,2-Dipalmitoylphosphatidylcholine	24-55	neuropeptide Y	Homo sapiens	138-141
34426114-1	2021	Oligomannose-coated liposomes (OMLs) comprised of dipalmitoylphosphatidylcholine, cholesterol and Man3-DPPE at a molar ratio of 1:1:0.1 and particle diameters of about 1000 nm can induce liposome-encased antigen-specific strong Th1 immunity.	1,2-Dipalmitoylphosphatidylcholine	50-80	negative elongation factor complex member C/D, Th1l	Mus musculus	228-231
34310940-1	2021	Time resolved fluorescence and differential scanning calorimetry were used to examine how two amino acids, L-Phenylalanine (L-PA) and N-Acetyl-DL-tryptophan (NAT), affect the temperature-dependent membrane affinity of two structurally similar coumarin solutes for DPPC vesicles.	1,2-Dipalmitoylphosphatidylcholine	264-268	bromodomain containing 2	Homo sapiens	158-161
34310940-5	2021	Adding NAT to DPPC vesicle-containing solutions changed C151 and C152 affinity for the DPPC membranes in unexpected ways.	1,2-Dipalmitoylphosphatidylcholine	14-18	bromodomain containing 2	Homo sapiens	7-10
34310940-5	2021	Adding NAT to DPPC vesicle-containing solutions changed C151 and C152 affinity for the DPPC membranes in unexpected ways.	1,2-Dipalmitoylphosphatidylcholine	87-91	bromodomain containing 2	Homo sapiens	7-10
34264682-6	2021	The interactions between PEPc-PMAA and mimic cells were investigated by the measurements of membrane fluidity and cargo leakage from 1,2-dipalmitoyl-sn-glycerol-3-phosphocholine and 1,2-dipalmitoyl-sn-glycerol-3-phospho-(1-rac-glycerol) (DPPG) liposomes.	1,2-Dipalmitoylphosphatidylcholine	133-177	peptidase C	Homo sapiens	25-29
34572302-5	2021	A novel gene therapy approach was developed using dipalmitoylphosphatidylcholine formulated with iron oxide (DPPC-Fe3O4) to carry the B-domain-deleted (BDD)-FVIII plasmid, which was delivered into the FVIII KO mice via tail vein injection.	1,2-Dipalmitoylphosphatidylcholine	50-80	coagulation factor VIII	Mus musculus	157-162
34170590-3	2021	In this work, we demonstrate the capability of tip-enhanced Raman spectroscopy (TERS) to probe the molecular organization of supported DPPC monolayers on Au (111), prepared using the Langmuir-Blodgett (LB) technique.	1,2-Dipalmitoylphosphatidylcholine	135-139	TOR signaling pathway regulator	Homo sapiens	47-50
35388392-1	2022	A metal-binding peptide appending cholic acid, Chol-MBP, formed bicelles by mixing with 1,2-dipalmitoyl-sn-glycero-3-phosphorylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	88-134	myelin basic protein	Homo sapiens	52-55
34105546-1	2021	The first vibrational sum-frequency generation (VSFG) spectra of chondroitin sulfate (CS) interacting with dipalmitoyl phosphatidylcholine (DPPC) at air-liquid interface are reported here, collected at a laser repetition rate of 100 kHz.	1,2-Dipalmitoylphosphatidylcholine	107-138	citrate synthase	Homo sapiens	86-88
34105546-1	2021	The first vibrational sum-frequency generation (VSFG) spectra of chondroitin sulfate (CS) interacting with dipalmitoyl phosphatidylcholine (DPPC) at air-liquid interface are reported here, collected at a laser repetition rate of 100 kHz.	1,2-Dipalmitoylphosphatidylcholine	140-144	citrate synthase	Homo sapiens	86-88
34105546-2	2021	By studying the VSFG spectra in the regions of 1050-1450 cm-1, 2750-3180 cm-1, and 3200-3825 cm-1, it was concluded that in the presence of Ca2+ ions, the head groups together with the head-group-bound water molecules in the DPPC monolayer are strongly influenced by the interaction with CS, while the organization of the phospholipid tails remains mostly unchanged.	1,2-Dipalmitoylphosphatidylcholine	225-229	citrate synthase	Homo sapiens	288-290
35483419-6	2022	Using large unilamellar vesicles, we found that upon replacing 10 mol% DPPC with either C16:0 or C18:0 ceramide, or 16:0 diacylglycerol (dag), lipid domains persisted to higher temperatures.	1,2-Dipalmitoylphosphatidylcholine	71-75	Bardet-Biedl syndrome 9	Homo sapiens	97-100
35483419-7	2022	However, when DPPC was replaced with short chain (C6:0 or C12:0) or very long chain (C24:0) ceramides, or ceramides with unsaturated acyl chains of any length (C6:1(3), C6:1(5), C18:1, and C24:1), as well as C18:1-dag, lipid domains were destabilized, melting at lower temperatures than those in the DPPC/DOPC/cholesterol system.	1,2-Dipalmitoylphosphatidylcholine	14-18	Bardet-Biedl syndrome 9	Homo sapiens	178-181
35483419-7	2022	However, when DPPC was replaced with short chain (C6:0 or C12:0) or very long chain (C24:0) ceramides, or ceramides with unsaturated acyl chains of any length (C6:1(3), C6:1(5), C18:1, and C24:1), as well as C18:1-dag, lipid domains were destabilized, melting at lower temperatures than those in the DPPC/DOPC/cholesterol system.	1,2-Dipalmitoylphosphatidylcholine	14-18	Bardet-Biedl syndrome 9	Homo sapiens	208-211
35621373-0	2022	Effect of biphosphate salt on dipalmitoylphosphatidylcholine bilayer deformation by Tat polypeptide.	1,2-Dipalmitoylphosphatidylcholine	30-60	tyrosine aminotransferase	Homo sapiens	84-87
35621373-2	2022	Here we report all-atom molecular dynamics simulations to investigate how a biphosphate salt in a solvent affects the interaction of a CPP, HIV-1 Tat peptide with model dipalmitoylphosphatidylcholine (DPPC) lipid bilayer.	1,2-Dipalmitoylphosphatidylcholine	169-199	tyrosine aminotransferase	Homo sapiens	146-149
35621373-2	2022	Here we report all-atom molecular dynamics simulations to investigate how a biphosphate salt in a solvent affects the interaction of a CPP, HIV-1 Tat peptide with model dipalmitoylphosphatidylcholine (DPPC) lipid bilayer.	1,2-Dipalmitoylphosphatidylcholine	201-205	tyrosine aminotransferase	Homo sapiens	146-149
35388392-1	2022	A metal-binding peptide appending cholic acid, Chol-MBP, formed bicelles by mixing with 1,2-dipalmitoyl-sn-glycero-3-phosphorylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	136-140	myelin basic protein	Homo sapiens	52-55
35388392-2	2022	Coordination of Chol-MBP with Cu2+ stabilized DPPC bicelles against dilution and contamination of serum proteins, enabling extended blood circulation.	1,2-Dipalmitoylphosphatidylcholine	46-50	myelin basic protein	Homo sapiens	21-24
2819075-6	1989	SP-A was reconstituted into a binary lipid mixture of acyl chain perdeuterated dipalmitoylphosphatidylcholine/dipalmitoylphosphatidylglycerol (DPPC-d62/DPPG, 85:15 w/w), a ratio which approximates that in surfactant.	1,2-Dipalmitoylphosphatidylcholine	79-109	pulmonary surfactant-associated protein A	Bos taurus	0-4
35547841-4	2022	With examples of zwitterionic dipalmitoyl phosphatidyl choline, cholesterol, and anionic sodium dodecyl sulphate, we show that surfactants form micellar aggregates that selectively adhere to the specific regions of S1 domain of the Spike protein that are responsible for binding with ACE2 receptors and virus transmission into the cells.	1,2-Dipalmitoylphosphatidylcholine	30-62	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	232-237
35547841-4	2022	With examples of zwitterionic dipalmitoyl phosphatidyl choline, cholesterol, and anionic sodium dodecyl sulphate, we show that surfactants form micellar aggregates that selectively adhere to the specific regions of S1 domain of the Spike protein that are responsible for binding with ACE2 receptors and virus transmission into the cells.	1,2-Dipalmitoylphosphatidylcholine	30-62	angiotensin converting enzyme 2	Homo sapiens	284-288
35143598-4	2022	Interestingly, the modified MOF-LIC-SA displayed rapid (~5 min) and efficient extraction towards U(VI) and Th(IV) from an aqueous medium and modified MOF-LIC-DPPC displayed enhanced thermal stability (600  C) compared with the parent MOF-LIC-1 (450  C).	1,2-Dipalmitoylphosphatidylcholine	158-162	dynein cytoplasmic 1 light intermediate chain 1	Homo sapiens	238-243
35367966-7	2022	Notwithstanding the age and gender differences, and a higher p-tau, Abeta 42, and LDL-cholesterol in the discovery cohort, CSF concentrations of dipalmitoyl-PC (PC32a:0) were significantly associated with p-tau in both cohorts.	1,2-Dipalmitoylphosphatidylcholine	145-159	microtubule associated protein tau	Homo sapiens	63-66
35367966-7	2022	Notwithstanding the age and gender differences, and a higher p-tau, Abeta 42, and LDL-cholesterol in the discovery cohort, CSF concentrations of dipalmitoyl-PC (PC32a:0) were significantly associated with p-tau in both cohorts.	1,2-Dipalmitoylphosphatidylcholine	145-159	microtubule associated protein tau	Homo sapiens	207-210
2516855-0	1989	Interaction of human apolipoprotein A-I with dipalmitoylphosphatidylcholine in vesicular and micellar complexes.	1,2-Dipalmitoylphosphatidylcholine	45-75	apolipoprotein A1	Homo sapiens	21-39
2516855-1	1989	The interactions of human apolipoprotein A-I (apo A-I) with dipalmitoylphosphatidylcholine (DPPC) in vesicular complexes at low protein concentrations and in micellar complexes at high protein concentrations are compared.	1,2-Dipalmitoylphosphatidylcholine	60-90	apolipoprotein A1	Homo sapiens	26-44
2516855-1	1989	The interactions of human apolipoprotein A-I (apo A-I) with dipalmitoylphosphatidylcholine (DPPC) in vesicular complexes at low protein concentrations and in micellar complexes at high protein concentrations are compared.	1,2-Dipalmitoylphosphatidylcholine	60-90	apolipoprotein A1	Homo sapiens	46-53
2516855-1	1989	The interactions of human apolipoprotein A-I (apo A-I) with dipalmitoylphosphatidylcholine (DPPC) in vesicular complexes at low protein concentrations and in micellar complexes at high protein concentrations are compared.	1,2-Dipalmitoylphosphatidylcholine	92-96	apolipoprotein A1	Homo sapiens	26-44
2516855-1	1989	The interactions of human apolipoprotein A-I (apo A-I) with dipalmitoylphosphatidylcholine (DPPC) in vesicular complexes at low protein concentrations and in micellar complexes at high protein concentrations are compared.	1,2-Dipalmitoylphosphatidylcholine	92-96	apolipoprotein A1	Homo sapiens	46-53
2516855-6	1989	The binding equilibrium of apo A-I as to DPPC vesicles at low protein concentrations, as studied by hydrophobic labeling of the bilayer-penetrating segment, is reached within about 1 h, while the formation of micellar complexes at high protein concentrations takes about 24 h at 42 degrees C. Time-dependent labeling studies involving photoreactive phosphatidylcholine (PC) with high apo A-I concentrations suggested an initial interaction with the head group region of the bilayer followed by interaction with the tail ends of the acyl chains of the lipid.	1,2-Dipalmitoylphosphatidylcholine	41-45	apolipoprotein A1	Homo sapiens	27-34
2593200-5	1989	Our results show that CRP binds to liposomes containing DPPC and phosphatidylglycerol (PG).	1,2-Dipalmitoylphosphatidylcholine	56-60	C-reactive protein	Homo sapiens	22-25
2505889-4	1989	Surface potential data clearly indicate also that insulin penetration/interaction with DPPC monolayers is enhanced in the presence of the second studied constituent of these monolayers in the order DPPC + stearylamine greater than DPPC + cholesteryl betainate greater than DPPC + cholesterol greater than DPPC.	1,2-Dipalmitoylphosphatidylcholine	198-202	insulin	Homo sapiens	50-57
2525936-1	1989	The interaction of bis-GMA analogues with dipalmitoylphosphatidylcholine liposomes was studied by 1H and 13C nuclear magnetic resonance spectroscopy.	1,2-Dipalmitoylphosphatidylcholine	42-72	myelin associated glycoprotein	Homo sapiens	23-26
2525936-3	1989	The mobility of iso-bis-GMA was strongly disturbed by dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	54-84	myelin associated glycoprotein	Homo sapiens	24-27
2494377-1	1989	Apo C1, a 6.5 kD protein component of VLDL, inhibits the hydrolysis of DPPC vesicles by pancreatic PLA2 and the hydrolysis of cellular phospholipids by endogenous phospholipases by interaction with the substrate.	1,2-Dipalmitoylphosphatidylcholine	71-75	phospholipase A2 group IB	Homo sapiens	99-103
2725816-4	1989	DPPC-induced reductions in [3H]ACh levels were blocked by 100 microM eserine, a tertiary amine cholinesterase inhibitor, but not with 100 microM neostigmine, a quaternary ammonium inhibitor.	1,2-Dipalmitoylphosphatidylcholine	0-4	butyrylcholinesterase	Rattus norvegicus	95-109
2505889-2	1989	Surface potential (delta V) measurements were performed to assess information on insulin penetration/interaction with dipalmitoylphosphatidylcholine (DPPC) monolayers spread at the water-air interface.	1,2-Dipalmitoylphosphatidylcholine	118-148	insulin	Homo sapiens	81-88
2505889-2	1989	Surface potential (delta V) measurements were performed to assess information on insulin penetration/interaction with dipalmitoylphosphatidylcholine (DPPC) monolayers spread at the water-air interface.	1,2-Dipalmitoylphosphatidylcholine	150-154	insulin	Homo sapiens	81-88
2505889-4	1989	Surface potential data clearly indicate also that insulin penetration/interaction with DPPC monolayers is enhanced in the presence of the second studied constituent of these monolayers in the order DPPC + stearylamine greater than DPPC + cholesteryl betainate greater than DPPC + cholesterol greater than DPPC.	1,2-Dipalmitoylphosphatidylcholine	87-91	insulin	Homo sapiens	50-57
2505889-4	1989	Surface potential data clearly indicate also that insulin penetration/interaction with DPPC monolayers is enhanced in the presence of the second studied constituent of these monolayers in the order DPPC + stearylamine greater than DPPC + cholesteryl betainate greater than DPPC + cholesterol greater than DPPC.	1,2-Dipalmitoylphosphatidylcholine	198-202	insulin	Homo sapiens	50-57
2505889-4	1989	Surface potential data clearly indicate also that insulin penetration/interaction with DPPC monolayers is enhanced in the presence of the second studied constituent of these monolayers in the order DPPC + stearylamine greater than DPPC + cholesteryl betainate greater than DPPC + cholesterol greater than DPPC.	1,2-Dipalmitoylphosphatidylcholine	198-202	insulin	Homo sapiens	50-57
2505889-4	1989	Surface potential data clearly indicate also that insulin penetration/interaction with DPPC monolayers is enhanced in the presence of the second studied constituent of these monolayers in the order DPPC + stearylamine greater than DPPC + cholesteryl betainate greater than DPPC + cholesterol greater than DPPC.	1,2-Dipalmitoylphosphatidylcholine	198-202	insulin	Homo sapiens	50-57
2609973-1	1989	The interaction of the anticancer drug, etoposide (VP16-213), with DPPC bilayer vesicles was investigated by DSC and Laser Raman techniques.	1,2-Dipalmitoylphosphatidylcholine	67-71	host cell factor C1	Homo sapiens	51-55
2609973-2	1989	The results present the fact that the incorporation of VP16-213 into aqueous dispersion of DPPC not only shifted the temperatures of phase transition towards higher value but also broadened the half-height width.	1,2-Dipalmitoylphosphatidylcholine	91-95	host cell factor C1	Homo sapiens	55-59
2609973-3	1989	The Raman spectra of the DPPC liposome in the C-H symmetric strech vibration lost intensity near 2850cm-1, therefore, it can be predicted that VP16-213 is localized at C1-C9 methylene region of the bilayer, which leads to the increase of the membrane"s regularity and the decrease of its fluidity.	1,2-Dipalmitoylphosphatidylcholine	25-29	host cell factor C1	Homo sapiens	143-147
2543460-4	1989	This difference is large enough to be of diagnostic value for all three spin labels in the interdigitated bilayers of dihexadecylphosphatidylcholine, dipalmitoylphosphatidylcholine/ethanol, and 1,3-dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	150-180	spindlin 1	Homo sapiens	72-76
3143410-7	1988	The plot of gamma against pi i for adsorption of apolipoprotein A-I to dipalmitoylphosphatidylcholine (DPPC) monolayers shows an inflection at pi i = 8 dyn/cm; at this pi, the DPPC monolayer undergoes a phase transition from liquid (expanded) to solid (condensed) state.	1,2-Dipalmitoylphosphatidylcholine	71-101	apolipoprotein A1	Homo sapiens	49-67
3143410-7	1988	The plot of gamma against pi i for adsorption of apolipoprotein A-I to dipalmitoylphosphatidylcholine (DPPC) monolayers shows an inflection at pi i = 8 dyn/cm; at this pi, the DPPC monolayer undergoes a phase transition from liquid (expanded) to solid (condensed) state.	1,2-Dipalmitoylphosphatidylcholine	103-107	apolipoprotein A1	Homo sapiens	49-67
3143410-7	1988	The plot of gamma against pi i for adsorption of apolipoprotein A-I to dipalmitoylphosphatidylcholine (DPPC) monolayers shows an inflection at pi i = 8 dyn/cm; at this pi, the DPPC monolayer undergoes a phase transition from liquid (expanded) to solid (condensed) state.	1,2-Dipalmitoylphosphatidylcholine	176-180	apolipoprotein A1	Homo sapiens	49-67
3403556-10	1988	The effect of [PLA2] and [PC] on the hydrolysis reaction is similar to that found with pure DPPC unilamellar vesicles in their thermotropic phase transition region.	1,2-Dipalmitoylphosphatidylcholine	92-96	phospholipase A2 group IB	Homo sapiens	15-19
3167108-0	1988	[The effect of calcium and magnesium ions on the interaction of calcium-binding proteins parvalbumin and alpha-lactalbumin with dipalmitoylphosphatidylcholine vesicles].	1,2-Dipalmitoylphosphatidylcholine	128-158	parvalbumin	Homo sapiens	89-100
3396665-3	1988	Therefore, we have examined the effect of TCE on the intra- and extracellular surfactant pools and the activity of phospholipase A2, an enzyme which controls the remodeling of phosphatidylcholine to dipalmitoylphosphatidylcholine, the primary constituent of the pulmonary surfactant.	1,2-Dipalmitoylphosphatidylcholine	199-229	phospholipase A2, group IB, pancreas	Mus musculus	115-131
3370214-2	1988	Accordingly, the effects of PAF and related alkyl ether and acyl analogs on phase transition thermodynamics of dipalmitoylphosphatidylcholine (DPPC) were studied using fluorescence polarization of the fluorescent probe, 1,6-diphenyl-1,3,5-hexatriene (DPH).	1,2-Dipalmitoylphosphatidylcholine	111-141	PCNA clamp associated factor	Homo sapiens	28-31
3370214-2	1988	Accordingly, the effects of PAF and related alkyl ether and acyl analogs on phase transition thermodynamics of dipalmitoylphosphatidylcholine (DPPC) were studied using fluorescence polarization of the fluorescent probe, 1,6-diphenyl-1,3,5-hexatriene (DPH).	1,2-Dipalmitoylphosphatidylcholine	143-147	PCNA clamp associated factor	Homo sapiens	28-31
3167108-0	1988	[The effect of calcium and magnesium ions on the interaction of calcium-binding proteins parvalbumin and alpha-lactalbumin with dipalmitoylphosphatidylcholine vesicles].	1,2-Dipalmitoylphosphatidylcholine	128-158	lactalbumin alpha	Homo sapiens	105-122
2434489-0	1987	Effect of myelin basic protein on the thermotropic behavior of aqueous dispersions of neutral and anionic glycosphingolipids and their mixtures with dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	149-179	myelin basic protein	Homo sapiens	10-30
3348816-0	1988	Induction of a latency period in the time-course of phospholipase A2 action on dipalmitoylphosphatidylcholine liposomes in the gel phase.	1,2-Dipalmitoylphosphatidylcholine	79-109	phospholipase A2 group IB	Homo sapiens	52-68
3348816-1	1988	The hydrolysis of dipalmitoylphosphatidylcholine liposomes by porcine pancreatic phospholipase A2 was studied at 31 degrees C, i.e., with the substrate in the gel phase.	1,2-Dipalmitoylphosphatidylcholine	18-48	phospholipase A2 group IB	Homo sapiens	81-97
3124835-4	1988	At 1 mM 2-thioPC increasing the concentration of Triton X-100 from 4 to 16 mM changes the specific activity of bee-venom phospholipase A2 from 96.9 to 17.9 mumol/min/mg, about one order of magnitude lower than dipalmitoyl phosphatidylcholine hydrolysis in micelles of similar composition.	1,2-Dipalmitoylphosphatidylcholine	210-241	phospholipase A2 group IB	Homo sapiens	121-137
3250632-1	1988	Membrane fluidity and osmotic sensitivity were examined in DPPC liposomes treated with phospholipase A2 (PL.A2) in the presence of Ca2+ or Mg2+.	1,2-Dipalmitoylphosphatidylcholine	59-63	phospholipase A2 group IB	Homo sapiens	87-103
3250632-1	1988	Membrane fluidity and osmotic sensitivity were examined in DPPC liposomes treated with phospholipase A2 (PL.A2) in the presence of Ca2+ or Mg2+.	1,2-Dipalmitoylphosphatidylcholine	59-63	phospholipase A2 group IB	Homo sapiens	105-110
3654625-0	1987	The activation of porcine pancreatic phospholipase A2 by dipalmitoylphosphatidylcholine large unilamellar vesicles.	1,2-Dipalmitoylphosphatidylcholine	57-87	phospholipase A2 group IB	Homo sapiens	37-53
3654625-2	1987	Previous work from this laboratory and others has shown that the hydrolysis of pure dipalmitoylphosphatidylcholine (DPPC) liposomes by porcine pancreatic phospholipase A2 in the vicinity of the gel-to-liquid crystal phase transition is characterized by a slow initial phase followed by an apparent burst of activity.	1,2-Dipalmitoylphosphatidylcholine	84-114	phospholipase A2 group IB	Homo sapiens	154-170
3654625-2	1987	Previous work from this laboratory and others has shown that the hydrolysis of pure dipalmitoylphosphatidylcholine (DPPC) liposomes by porcine pancreatic phospholipase A2 in the vicinity of the gel-to-liquid crystal phase transition is characterized by a slow initial phase followed by an apparent burst of activity.	1,2-Dipalmitoylphosphatidylcholine	116-120	phospholipase A2 group IB	Homo sapiens	154-170
3436953-6	1987	The ability of SEP1-15 and SEP1-20 to induce leakage of carboxyfluorescein from the inside of dipalmitoyl-DL-alpha-phosphatidylcholine (DPPC) or DPPC-dipalmitoyl-DL-alpha-phosphatidylglycerol (3:1) vesicles was much greater than that of other peptides.	1,2-Dipalmitoylphosphatidylcholine	136-140	septin 1	Homo sapiens	27-34
3672025-1	1987	An assay using 2-(1-14C)palmitoyl-labelled dipalmitoyl phosphatidylcholine substrate for the determination of serum phospholipase A2 (PLA2) activity is described and validated.	1,2-Dipalmitoylphosphatidylcholine	43-74	phospholipase A2 group IB	Homo sapiens	116-132
3672025-1	1987	An assay using 2-(1-14C)palmitoyl-labelled dipalmitoyl phosphatidylcholine substrate for the determination of serum phospholipase A2 (PLA2) activity is described and validated.	1,2-Dipalmitoylphosphatidylcholine	43-74	phospholipase A2 group IB	Homo sapiens	134-138
3663745-1	1987	Transacetylation of labeled CoA-oleate and oleate into liposomes from dipalmitoyl phosphatidylcholine catalyzed by phospholipase A2 from rat liver mitochondria was studied.	1,2-Dipalmitoylphosphatidylcholine	70-101	phospholipase A2 group IB	Rattus norvegicus	115-131
3566802-3	1987	In the present experiments, the influence of the amphiphilic drugs ambroxol, imipramine, chloroquine and chlorphentermine on the hydrolysis of dipalmitoyl-phosphatidylcholine (DPPC) unilamellar liposomes by bee venom phospholipase A2 (PLase A2) was studied.	1,2-Dipalmitoylphosphatidylcholine	143-174	phospholipase A2 group IB	Homo sapiens	217-233
3566802-3	1987	In the present experiments, the influence of the amphiphilic drugs ambroxol, imipramine, chloroquine and chlorphentermine on the hydrolysis of dipalmitoyl-phosphatidylcholine (DPPC) unilamellar liposomes by bee venom phospholipase A2 (PLase A2) was studied.	1,2-Dipalmitoylphosphatidylcholine	143-174	phospholipase A2 group IB	Homo sapiens	235-243
3343241-6	1988	This phospholipase A2 shows considerably more activity when assayed in the presence of glycerol, regardless of whether the substrate, dipalmitoylphosphatidylcholine, is in the form of sonicated vesicles or mixed micelles with the nonionic surfactant Triton X-100.	1,2-Dipalmitoylphosphatidylcholine	134-164	phospholipase A2, group IB, pancreas	Mus musculus	5-21
3343241-11	1988	This yields a 2500-fold purification of the membrane-bound phospholipase A2 with a 25% recovery and a specific activity of about 800 nmol min-1 mg-1 toward 100 microM dipalmitoylphosphatidylcholine in mixed micelles.	1,2-Dipalmitoylphosphatidylcholine	167-197	phospholipase A2, group IB, pancreas	Mus musculus	59-75
3390478-1	1988	Studies were carried out of temperature quenching of self-fluorescence of cytochrome P-450 in solution and liposomes from natural phosphatidylcholine, dimiristoylphosphatidylcholine, dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	183-213	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	74-90
3396853-0	1988	Interactions of calcium binding proteins, parvalbumin and alpha-lactalbumin, with dipalmitoylphosphatidylcholine vesicles.	1,2-Dipalmitoylphosphatidylcholine	82-112	parvalbumin	Homo sapiens	42-53
3396853-0	1988	Interactions of calcium binding proteins, parvalbumin and alpha-lactalbumin, with dipalmitoylphosphatidylcholine vesicles.	1,2-Dipalmitoylphosphatidylcholine	82-112	lactalbumin alpha	Homo sapiens	58-75
3801467-1	1987	The localization of the effects of DDT (5-50 mol%) addition on the acyl chain dynamics in unilamellar vesicles of two phosphatidylcholines (DPPC and egg PC) has been investigated by steady-state fluorescence polarization of a series of n-(9-anthroyloxy) fatty acids (n = 2, 6, 9, 12 and 16) whose fluorophore is located at a graded series of depths from the surface to the centre of the bilayer.	1,2-Dipalmitoylphosphatidylcholine	140-144	D-dopachrome tautomerase	Homo sapiens	35-38
3801467-2	1987	The results show that DDT is a fluidizer of DPPC and egg PC bilayers.	1,2-Dipalmitoylphosphatidylcholine	44-48	D-dopachrome tautomerase	Homo sapiens	22-25
3801467-3	1987	The increase in microviscosity of DPPC bilayers at 23 degrees C begins at the centre of the bilayer (5 mol% DDT) and proceeds outward to the surface with increasing concentration of DDT (17 mol%).	1,2-Dipalmitoylphosphatidylcholine	34-38	D-dopachrome tautomerase	Homo sapiens	108-111
3801467-3	1987	The increase in microviscosity of DPPC bilayers at 23 degrees C begins at the centre of the bilayer (5 mol% DDT) and proceeds outward to the surface with increasing concentration of DDT (17 mol%).	1,2-Dipalmitoylphosphatidylcholine	34-38	D-dopachrome tautomerase	Homo sapiens	182-185
3801467-4	1987	This pattern of effects is not evident in fluid bilayers of DPPC at 54 degrees C or egg PC at 23 degrees C. DDT (33 mol%) also lowers the phase transition temperature of DPPC bilayers by approximately 2 Cdeg.	1,2-Dipalmitoylphosphatidylcholine	170-174	D-dopachrome tautomerase	Homo sapiens	108-111
3768316-5	1986	At temperatures above the phase transition temperature of DPPC (Tc), an increase in both C11 and eta 11 is noticed when cholesterol is incorporated in the multibilayers.	1,2-Dipalmitoylphosphatidylcholine	58-62	RNA polymerase III subunit K	Homo sapiens	89-92
3158653-2	1985	Sharp increases in the quenching constants were found in samples of ATPase reconstituted with dimyristoyl-phosphatidylcholine and dipalmitoylphosphatidylcholine at temperatures slightly below the Tc transition temperature of the pure phospholipid.	1,2-Dipalmitoylphosphatidylcholine	130-160	dynein axonemal heavy chain 8	Homo sapiens	68-74
2942187-2	1986	The binding calculations indicated a dissociation constant of 6.98 +/- 1.5 muM at 48 degrees C, i.e., above the transition temperature (Tc) of the pure phospholipid, with a number of binding sites of 1 per 22 +/- 2.5 molecules of phospholipid, while at 23 degrees C, i.e., below the Tc of the pure phospholipid, the dissociation constant was 9.15 +/- 0.24 muM and the number of binding sites was 1 per each 29 +/- 1.6 molecules of DPPC.	1,2-Dipalmitoylphosphatidylcholine	431-435	latexin	Homo sapiens	75-78
2942187-2	1986	The binding calculations indicated a dissociation constant of 6.98 +/- 1.5 muM at 48 degrees C, i.e., above the transition temperature (Tc) of the pure phospholipid, with a number of binding sites of 1 per 22 +/- 2.5 molecules of phospholipid, while at 23 degrees C, i.e., below the Tc of the pure phospholipid, the dissociation constant was 9.15 +/- 0.24 muM and the number of binding sites was 1 per each 29 +/- 1.6 molecules of DPPC.	1,2-Dipalmitoylphosphatidylcholine	431-435	latexin	Homo sapiens	356-359
3022496-1	1986	1H NMR studies on DPPC vesicles labeled with the spin labels (1,14) or (12,3) have shown that both of the spin labels influence the fatty acid side chains as well as the choline head groups.	1,2-Dipalmitoylphosphatidylcholine	18-22	spindlin 1	Homo sapiens	49-53
3022496-1	1986	1H NMR studies on DPPC vesicles labeled with the spin labels (1,14) or (12,3) have shown that both of the spin labels influence the fatty acid side chains as well as the choline head groups.	1,2-Dipalmitoylphosphatidylcholine	18-22	spindlin 1	Homo sapiens	106-110
3729948-1	1986	The effect of apolipoprotein C-II (apoC-II) and a synthetic fragment of apoC-II corresponding to residues 56-79 on the lipoprotein lipase (LpL) catalyzed hydrolysis of trioleoylglycerol in a monolayer of egg phosphatidylcholine and of dipalmitoylphosphatidylcholine vesicles was examined.	1,2-Dipalmitoylphosphatidylcholine	235-265	lipoprotein lipase	Homo sapiens	119-137
3729948-1	1986	The effect of apolipoprotein C-II (apoC-II) and a synthetic fragment of apoC-II corresponding to residues 56-79 on the lipoprotein lipase (LpL) catalyzed hydrolysis of trioleoylglycerol in a monolayer of egg phosphatidylcholine and of dipalmitoylphosphatidylcholine vesicles was examined.	1,2-Dipalmitoylphosphatidylcholine	235-265	lipoprotein lipase	Homo sapiens	139-142
3755628-3	1986	Binding interactions between human angiotensin II and dipalmitoylphosphatidylcholine bilayer vesicles have been detected by measuring the selective proton spin-lattice relaxation rates of aromatic protons within the peptide.	1,2-Dipalmitoylphosphatidylcholine	54-84	angiotensinogen	Homo sapiens	35-49
3932344-1	1985	The interaction between apolipoprotein A-I and small unilamellar vesicles of dipalmitoylphosphatidylcholine at the lipid phase transition resulted in complete release of vesicle contents at molar ratios of lipid to protein from 4000:1 down to 50:1.	1,2-Dipalmitoylphosphatidylcholine	77-107	apolipoprotein A1	Homo sapiens	24-42
3932344-8	1985	Kinetic analysis of the interaction between apo-A-I and dipalmitoylphosphatidylcholine vesicles below Tc indicated that about 1 in 500 collisions leads to a stable apo-A-I-vesicle complex.	1,2-Dipalmitoylphosphatidylcholine	56-86	apolipoprotein A1	Homo sapiens	164-171
2996648-9	1985	The results from CSL indicate that close to the lipid-water interface the DPPC molecule is oriented approximately perpendicular to the bilayer in these low water-content systems.	1,2-Dipalmitoylphosphatidylcholine	74-78	chorionic somatomammotropin hormone like 1	Homo sapiens	17-20
3754257-0	1986	Hydrolysis of dipalmitoylphosphatidylcholine small unilamellar vesicles by porcine pancreatic phospholipase A2.	1,2-Dipalmitoylphosphatidylcholine	14-44	phospholipase A2 group IB	Homo sapiens	94-110
3754257-9	1986	These results lead us to conclude that two distinctly different steps precede rapid hydrolysis of dipalmitoylphosphatidylcholine small unilamellar vesicles by pancreatic phospholipase A2: a Ca2+-independent binding of the enzyme to the substrate vesicles, which for chemically pure bilayers occurs best in the gel phase.	1,2-Dipalmitoylphosphatidylcholine	98-128	phospholipase A2 group IB	Homo sapiens	170-186
3754258-0	1986	Hydrolysis of dipalmitoylphosphatidylcholine large unilamellar vesicles by porcine pancreatic phospholipase A2.	1,2-Dipalmitoylphosphatidylcholine	14-44	phospholipase A2 group IB	Homo sapiens	94-110
3754258-1	1986	The interaction between dipalmitoylphosphatidylcholine large unilamellar vesicles and porcine pancreatic phospholipase A2 has been studied under a variety of conditions.	1,2-Dipalmitoylphosphatidylcholine	24-54	phospholipase A2 group IB	Homo sapiens	105-121
3755063-2	1986	Cyclosporine A (CSA)-dipalmitoylphosphatidylcholine (DPPC) interactions were investigated using scanning calorimetry, infrared spectroscopy, and Raman spectroscopy.	1,2-Dipalmitoylphosphatidylcholine	21-51	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	16-19
3755063-2	1986	Cyclosporine A (CSA)-dipalmitoylphosphatidylcholine (DPPC) interactions were investigated using scanning calorimetry, infrared spectroscopy, and Raman spectroscopy.	1,2-Dipalmitoylphosphatidylcholine	53-57	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	16-19
2941415-1	1986	(Ca2+ + Mg2+)-ATPase from sarcoplasmic reticulum has been reconstituted with dipalmitoylphosphatidylcholine, and the activating effect of ATP and Ca2+ on this enzyme has been studied at different temperatures.	1,2-Dipalmitoylphosphatidylcholine	77-107	dynein axonemal heavy chain 8	Homo sapiens	14-20
3517295-3	1986	The fusion and aggregation properties of dipalmitoylphosphatidylcholine (DPPC) small, unilamellar liposomes, on the binding of insulin was studied by the techniques of resonance energy transfer of fluorescent labeled lipids, electron microscopy, and right-angle scattering.	1,2-Dipalmitoylphosphatidylcholine	41-71	insulin	Homo sapiens	127-134
3517295-3	1986	The fusion and aggregation properties of dipalmitoylphosphatidylcholine (DPPC) small, unilamellar liposomes, on the binding of insulin was studied by the techniques of resonance energy transfer of fluorescent labeled lipids, electron microscopy, and right-angle scattering.	1,2-Dipalmitoylphosphatidylcholine	73-77	insulin	Homo sapiens	127-134
3517295-4	1986	Within 1 h of adding insulin to DPPC liposomes at 25 degrees C, the average size of the liposomes increased from 239 to 361 A in diameter.	1,2-Dipalmitoylphosphatidylcholine	32-36	insulin	Homo sapiens	21-28
3754566-5	1986	The content of phosphatidylcholine (PC) and dipalmitoylphosphatidylcholine (DPPC) after treatment with PRL was demonstrated to be significantly higher than the control.	1,2-Dipalmitoylphosphatidylcholine	44-74	prolactin	Rattus norvegicus	103-106
3754566-5	1986	The content of phosphatidylcholine (PC) and dipalmitoylphosphatidylcholine (DPPC) after treatment with PRL was demonstrated to be significantly higher than the control.	1,2-Dipalmitoylphosphatidylcholine	76-80	prolactin	Rattus norvegicus	103-106
3997864-4	1985	For a given concentration of manoalide, the inhibition of phospholipase A2 activity toward dipalmitoylphosphatidylcholine/Triton X-100 mixed micelles is time-dependent and plateaus at about 85% inhibition of the initial velocity even after extensive preincubation.	1,2-Dipalmitoylphosphatidylcholine	91-121	phospholipase A2 group IB	Homo sapiens	58-74
3838669-2	1985	In vesicles composed of 50%/50% or 60%/40% DPPC/PS, Zn2+ and Cd2+-induced fusion at concentrations considerably lower than were required for Ca2+-induced fusion.	1,2-Dipalmitoylphosphatidylcholine	43-47	CD2 molecule	Bos taurus	61-64
3839352-1	1985	A standard mechanical test was used to quantify instant non-specific adhesion provided in vitro by fibronectin and to demonstrate how this adhesive found on circulating tumour cells can be decreased in potency by 65% when the adherents are coated with dipalmitoyl phosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	252-283	fibronectin 1	Homo sapiens	99-110
3919022-6	1985	Hydrolysis of multilamellar dipalmitoylphosphatidylcholine liposomes by purified phospholipase A2, was also inhibited by CRP.	1,2-Dipalmitoylphosphatidylcholine	28-58	phospholipase A2 group IB	Homo sapiens	81-97
3919022-6	1985	Hydrolysis of multilamellar dipalmitoylphosphatidylcholine liposomes by purified phospholipase A2, was also inhibited by CRP.	1,2-Dipalmitoylphosphatidylcholine	28-58	C-reactive protein	Homo sapiens	121-124
3838686-0	1985	Interaction between Ca2+ and dipalmitoylphosphatidylcholine membranes.	1,2-Dipalmitoylphosphatidylcholine	29-59	carbonic anhydrase 2	Homo sapiens	20-23
3838686-3	1985	The effect of Ca2+ on the molecular mobility in dipalmitoylphosphatidylcholine membranes was studied by steady-state and time-resolved measurements of fluorescence anisotropy.	1,2-Dipalmitoylphosphatidylcholine	48-78	carbonic anhydrase 2	Homo sapiens	14-17
2981926-11	1985	When the major structural lipid phosphatidyl choline was replaced by dipalmitoyl phosphatidyl choline, a synthetic phospholipid with no oxidizable double bonds, the resultant liposomes were totally resistant to lysis by the MPO-H2O2-chloride system.	1,2-Dipalmitoylphosphatidylcholine	69-101	myeloperoxidase	Homo sapiens	224-227
6712977-9	1984	Cholesterol (50 mol%) in a dipalmitoylphosphatidylcholine monolayer increased the rate of the lipoprotein lipase-catalyzed hydrolysis of tri[14C]oleoylglycerol, whereas cholesterol decreased the rate in a dioleoylphosphatidylcholine monolayer.	1,2-Dipalmitoylphosphatidylcholine	27-57	lipoprotein lipase	Bos taurus	94-112
4006876-1	1985	The 2H-NMR spectrum of the exchangeable hydrogens of the synthetic amphiphilic polypeptide, lys2-gly-leu24-lys2-ala-amide, was measured for the solid peptide at room temperature and, as a function of temperature, for the peptide incorporated into hydrated dipalmitoylphosphatidylcholine (DPPC) bilayers.	1,2-Dipalmitoylphosphatidylcholine	256-286	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	Homo sapiens	92-96
4006876-1	1985	The 2H-NMR spectrum of the exchangeable hydrogens of the synthetic amphiphilic polypeptide, lys2-gly-leu24-lys2-ala-amide, was measured for the solid peptide at room temperature and, as a function of temperature, for the peptide incorporated into hydrated dipalmitoylphosphatidylcholine (DPPC) bilayers.	1,2-Dipalmitoylphosphatidylcholine	288-292	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	Homo sapiens	92-96
6466689-7	1984	In contrast, the additions of triolein emulsified with Triton X-100 and dipalmitoylphosphatidylcholine vesicles enhanced the rate of tributyrin hydrolysis by hepatic triacylglycerol lipase.	1,2-Dipalmitoylphosphatidylcholine	72-102	lipase C, hepatic type	Homo sapiens	158-188
6466689-8	1984	In the presence of dipalmitoylphosphatidylcholine, the Vmax and Km values of hepatic triacylglycerol lipase for tributyrin were 41 mumol/mg protein per h and 0.12 mM, respectively, indicating that the enhancement of hepatic triacylglycerol lipase activity for tributyrin by dipalmitoylphosphatidycholine vesicles was mainly due to increase in the Vmax.	1,2-Dipalmitoylphosphatidylcholine	19-49	lipase C, hepatic type	Homo sapiens	77-107
6466689-8	1984	In the presence of dipalmitoylphosphatidylcholine, the Vmax and Km values of hepatic triacylglycerol lipase for tributyrin were 41 mumol/mg protein per h and 0.12 mM, respectively, indicating that the enhancement of hepatic triacylglycerol lipase activity for tributyrin by dipalmitoylphosphatidycholine vesicles was mainly due to increase in the Vmax.	1,2-Dipalmitoylphosphatidylcholine	19-49	lipase C, hepatic type	Homo sapiens	216-246
6466700-7	1984	However, on chromatography of the trypsin-treated enzyme after incubation with dipalmitoylphosphatidylcholine vesicles, a part of hepatic triacylglycerol lipase that retained esterase activity was eluted separately from the dipalmitoylphosphatidylcholine vesicles.	1,2-Dipalmitoylphosphatidylcholine	79-109	lipase C, hepatic type	Homo sapiens	130-160
6610595-6	1984	The antiulcer action of milk in rats could be related to its concentration of dipalmitoyl lecithin.	1,2-Dipalmitoylphosphatidylcholine	78-98	Weaning weight-maternal milk	Bos taurus	24-28
6549133-0	1984	Apolipoprotein B: removal of lipids by sodium cholate and reassociation of a lipid-free apoprotein with dipalmitoyl phosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	104-135	apolipoprotein B	Homo sapiens	0-16
6549133-4	1984	The peak position fraction of apoB taken from the column was used for reassociation with dipalmitoyl phosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	89-120	apolipoprotein B	Homo sapiens	30-34
6549133-4	1984	The peak position fraction of apoB taken from the column was used for reassociation with dipalmitoyl phosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	122-126	apolipoprotein B	Homo sapiens	30-34
6549133-5	1984	A soluble apoB-DPPC complex has been prepared by incubation of apoB-sodium cholate and DPPC-sodium cholate solutions at 42 degrees C, followed with detergent removal by extensive dialysis in the presence of a XAD-2 ion-exchange resin.	1,2-Dipalmitoylphosphatidylcholine	15-19	apolipoprotein B	Homo sapiens	10-14
6549133-5	1984	A soluble apoB-DPPC complex has been prepared by incubation of apoB-sodium cholate and DPPC-sodium cholate solutions at 42 degrees C, followed with detergent removal by extensive dialysis in the presence of a XAD-2 ion-exchange resin.	1,2-Dipalmitoylphosphatidylcholine	15-19	apolipoprotein B	Homo sapiens	63-67
6688442-1	1983	To elucidate the mechanism by which apolipoprotein C-II (apoC-II) enhances the activity of lipoprotein lipase (LpL), discoidal phospholipid complexes were prepared with apoC-III and di[(14)C]palmitoyl phosphatidylcholine (DPPC) and containing various amounts of apoC-II.	1,2-Dipalmitoylphosphatidylcholine	222-226	apolipoprotein C-II	Cavia porcellus	36-55
6546725-1	1984	The hydrolytic action of porcine pancreatic phospholipase A2 (PLA2) on cholesterol-containing dipalmitoylphosphatidylcholine liposomes was studied under various osmotic conditions by means of the phase transition release (PTR) technique.	1,2-Dipalmitoylphosphatidylcholine	94-124	phospholipase A2 group IB	Homo sapiens	44-60
6546725-1	1984	The hydrolytic action of porcine pancreatic phospholipase A2 (PLA2) on cholesterol-containing dipalmitoylphosphatidylcholine liposomes was studied under various osmotic conditions by means of the phase transition release (PTR) technique.	1,2-Dipalmitoylphosphatidylcholine	94-124	phospholipase A2 group IB	Homo sapiens	62-66
6713599-4	1984	The complexes of TPO with dimyristoyl phosphatidyl choline (DMPC), DPPC, and distearoyl phosphatidyl choline (DSPC) bilayers showed transition temperatures (Tc) which were lower than the characteristic ones shown by liposomes with the respective phospholipids alone.	1,2-Dipalmitoylphosphatidylcholine	67-71	LOW QUALITY PROTEIN: thyroid peroxidase	Bos taurus	17-20
6318838-1	1983	Purified preparations of Ca2+-dependent ATPase were lipid-deleted and incorporated into egg lecithin (EL) and dipalmitoyl lecithin (DPL) liposomes.	1,2-Dipalmitoylphosphatidylcholine	110-130	dynein axonemal heavy chain 8	Homo sapiens	40-46
6318838-1	1983	Purified preparations of Ca2+-dependent ATPase were lipid-deleted and incorporated into egg lecithin (EL) and dipalmitoyl lecithin (DPL) liposomes.	1,2-Dipalmitoylphosphatidylcholine	132-135	dynein axonemal heavy chain 8	Homo sapiens	40-46
6689106-2	1983	Glycyrrhizin was found to inhibit the PLA2-induced carboxyfluorescein (CF) release from D,L-dipalmitoyl phosphatidylcholine (DPPC) liposomes.	1,2-Dipalmitoylphosphatidylcholine	125-129	phospholipase A2 group IB	Homo sapiens	38-42
6689106-3	1983	Part of this inhibitory effect of glycyrrhizin on PLA2 is accounted for by the physical state of the substrate, the DPPC liposome membrane.	1,2-Dipalmitoylphosphatidylcholine	116-120	phospholipase A2 group IB	Homo sapiens	50-54
6400876-4	1983	Employing this approach, we present experimental NMR measurements using isotopic isomers of dipalmitoyl phosphatidyl choline in bilayer dispersions for the two stereospecific deuterium quadrupole couplings, the carbon-proton dipole couplings, and, preliminarily, the proton-proton dipole couplings, for the C-2 methylene segment of the sn-2 chain of dipalmitoyl phosphatidyl choline.	1,2-Dipalmitoylphosphatidylcholine	92-124	complement C2	Homo sapiens	307-310
6400876-4	1983	Employing this approach, we present experimental NMR measurements using isotopic isomers of dipalmitoyl phosphatidyl choline in bilayer dispersions for the two stereospecific deuterium quadrupole couplings, the carbon-proton dipole couplings, and, preliminarily, the proton-proton dipole couplings, for the C-2 methylene segment of the sn-2 chain of dipalmitoyl phosphatidyl choline.	1,2-Dipalmitoylphosphatidylcholine	92-124	solute carrier family 38 member 5	Homo sapiens	336-340
6688442-1	1983	To elucidate the mechanism by which apolipoprotein C-II (apoC-II) enhances the activity of lipoprotein lipase (LpL), discoidal phospholipid complexes were prepared with apoC-III and di[(14)C]palmitoyl phosphatidylcholine (DPPC) and containing various amounts of apoC-II.	1,2-Dipalmitoylphosphatidylcholine	222-226	apolipoprotein C-II	Cavia porcellus	57-64
6688442-1	1983	To elucidate the mechanism by which apolipoprotein C-II (apoC-II) enhances the activity of lipoprotein lipase (LpL), discoidal phospholipid complexes were prepared with apoC-III and di[(14)C]palmitoyl phosphatidylcholine (DPPC) and containing various amounts of apoC-II.	1,2-Dipalmitoylphosphatidylcholine	222-226	lipoprotein lipase	Cavia porcellus	91-109
6688442-1	1983	To elucidate the mechanism by which apolipoprotein C-II (apoC-II) enhances the activity of lipoprotein lipase (LpL), discoidal phospholipid complexes were prepared with apoC-III and di[(14)C]palmitoyl phosphatidylcholine (DPPC) and containing various amounts of apoC-II.	1,2-Dipalmitoylphosphatidylcholine	222-226	lipoprotein lipase	Cavia porcellus	111-114
6688442-2	1983	The rate of DPPC hydrolysis catalyzed by purified bovine milk LpL was determined on the isolated complexes.	1,2-Dipalmitoylphosphatidylcholine	12-16	lipoprotein lipase	Bos taurus	62-65
6688442-6	1983	The effect of apoC-II on enzyme kinetic parameters for LpL-catalyzed hydrolysis of DPPC complexes was compared to that on the parameters for hydrolysis of DPPC and trioleoylglycerol incorporated into guinea pig very low density lipoproteins (VLDL(p)) which lack the equivalent of human apoC-II.	1,2-Dipalmitoylphosphatidylcholine	83-87	apolipoprotein C-II	Cavia porcellus	14-21
6688442-6	1983	The effect of apoC-II on enzyme kinetic parameters for LpL-catalyzed hydrolysis of DPPC complexes was compared to that on the parameters for hydrolysis of DPPC and trioleoylglycerol incorporated into guinea pig very low density lipoproteins (VLDL(p)) which lack the equivalent of human apoC-II.	1,2-Dipalmitoylphosphatidylcholine	83-87	lipoprotein lipase	Cavia porcellus	55-58
6688442-9	1983	The rates of LpL-catalyzed hydrolysis of trioleoylglycerol and DPPC were determined at pH 7.4 and 8.5 in the presence and absence of apoC-II.	1,2-Dipalmitoylphosphatidylcholine	63-67	lipoprotein lipase	Cavia porcellus	13-16
6688442-10	1983	In the presence of apoC-II, the V(max) for DPPC hydrolysis in guinea pig VLDL(p) increased at both pH 7.4 and pH 8.5 (2.4- and 3.2-fold, respectively); the value of K(m) did not change at either pH (0.23 mm).	1,2-Dipalmitoylphosphatidylcholine	43-47	apolipoprotein C-II	Cavia porcellus	19-26
6809761-0	1982	Effect of dipalmitoylphosphatidylcholine vesicle curvature on the reaction with human apolipoprotein A-I.	1,2-Dipalmitoylphosphatidylcholine	10-40	apolipoprotein A1	Homo sapiens	86-104
6401739-0	1983	Factors affecting the size of complexes of dipalmitoylphosphatidylcholine with human apolipoprotein A-I.	1,2-Dipalmitoylphosphatidylcholine	43-73	apolipoprotein A1	Homo sapiens	85-103
6818987-4	1982	The initial velocities of the enzymatic reaction with purified human lecithin: cholesterol acyltransferase decreased in the order palmitoyloleoyl-PC greater than dipalmitoyl-PC greater than dimyristoyl-PC, at saturating micellar substrate levels.	1,2-Dipalmitoylphosphatidylcholine	162-176	lecithin-cholesterol acyltransferase	Homo sapiens	69-106
6809761-4	1982	The fractionated unilamellar vesicles and multilamellar vesicles of DPPC were reacted with human apolipoprotein A-I at 41 degrees C for periods from 1 to 120 h. The reaction mixtures were then passed through a Bio-Gel A-5m column to separate unreacted lipid vesicles and protein from micellar complexes of DPPC with apolipoprotein A-I.	1,2-Dipalmitoylphosphatidylcholine	68-72	apolipoprotein A1	Homo sapiens	97-115
7126647-8	1982	As with the heterogeneous antibodies, the monoclonal IgG1 is more efficient in mediating cellular uptake when the vesicles are in the "fluid" physical state (dimyristoylphosphatidylcholine at 37 degrees C) compared to "solid" (dipalmitoylphosphatidylcholine at 37 degrees C).	1,2-Dipalmitoylphosphatidylcholine	227-257	immunoglobulin heavy constant gamma 1 (G1m marker)	Mus musculus	53-57
7107600-1	1982	Interaction of purified bovine milk lipoprotein lipase (LpL) with sonicated vesicles of dipalmitoyl phosphatidylcholine in the gel phase is associated with an increase in the rate of the LpL-catalyzed hydrolysis of p-nitrophenyl butyrate.	1,2-Dipalmitoylphosphatidylcholine	88-119	lipoprotein lipase	Bos taurus	36-54
7107600-1	1982	Interaction of purified bovine milk lipoprotein lipase (LpL) with sonicated vesicles of dipalmitoyl phosphatidylcholine in the gel phase is associated with an increase in the rate of the LpL-catalyzed hydrolysis of p-nitrophenyl butyrate.	1,2-Dipalmitoylphosphatidylcholine	88-119	lipoprotein lipase	Bos taurus	56-59
7107600-1	1982	Interaction of purified bovine milk lipoprotein lipase (LpL) with sonicated vesicles of dipalmitoyl phosphatidylcholine in the gel phase is associated with an increase in the rate of the LpL-catalyzed hydrolysis of p-nitrophenyl butyrate.	1,2-Dipalmitoylphosphatidylcholine	88-119	lipoprotein lipase	Bos taurus	187-190
6896998-0	1982	Fusion of dipalmitoylphosphatidylcholine vesicles at 4 degrees C. Small sonicated dipalmitoylphosphatidylcholine vesicles when incubated at 4 degrees C and high concentrations are shown to fuse completely to vesicles about 700-A diameter in 7 days, and these further fuse to about 950 A diameter vesicles after 3-4 weeks.	1,2-Dipalmitoylphosphatidylcholine	10-40	Polykaryocytosis inducer	Homo sapiens	189-193
6896998-0	1982	Fusion of dipalmitoylphosphatidylcholine vesicles at 4 degrees C. Small sonicated dipalmitoylphosphatidylcholine vesicles when incubated at 4 degrees C and high concentrations are shown to fuse completely to vesicles about 700-A diameter in 7 days, and these further fuse to about 950 A diameter vesicles after 3-4 weeks.	1,2-Dipalmitoylphosphatidylcholine	82-112	Polykaryocytosis inducer	Homo sapiens	189-193
6896998-0	1982	Fusion of dipalmitoylphosphatidylcholine vesicles at 4 degrees C. Small sonicated dipalmitoylphosphatidylcholine vesicles when incubated at 4 degrees C and high concentrations are shown to fuse completely to vesicles about 700-A diameter in 7 days, and these further fuse to about 950 A diameter vesicles after 3-4 weeks.	1,2-Dipalmitoylphosphatidylcholine	82-112	Polykaryocytosis inducer	Homo sapiens	267-271
7107600-4	1982	With 0.5 mol % tri[14C]oleoylglycerol present in the dipalmitoyl phosphatidylcholine vesicles and in the presence of 20 mM Ca2+, the rate of p-nitrophenyl butyrate hydrolysis is decreased reciprocally compared to trioleoylglycerol hydrolysis and is dependent on apolipoprotein C-II.	1,2-Dipalmitoylphosphatidylcholine	53-84	apolipoprotein C2	Bos taurus	262-281
6180771-12	1982	The addition of both apolipoprotein C-II and substrate prior to the incubation with the Fab fragments was associated with an increased protective effect against inhibition of enzyme activity; remaining activity with dipalmitoylphosphatidylcholine-emulsified trioleoylglycerol was 40.6% and with Triton X-100-emulsified trioleoylglycerol, 45.4%.	1,2-Dipalmitoylphosphatidylcholine	216-246	apolipoprotein C2	Bos taurus	21-40
6180771-12	1982	The addition of both apolipoprotein C-II and substrate prior to the incubation with the Fab fragments was associated with an increased protective effect against inhibition of enzyme activity; remaining activity with dipalmitoylphosphatidylcholine-emulsified trioleoylglycerol was 40.6% and with Triton X-100-emulsified trioleoylglycerol, 45.4%.	1,2-Dipalmitoylphosphatidylcholine	216-246	FA complementation group B	Homo sapiens	88-91
6779866-4	1980	Binary mixtures of dimyristoylphosphatidylcholine and dipalmitoylphosphatidylcholine at various proportions react maximally with apo A-I at the onset of the phase transition, as judged by comparison with published phase diagrams; in this case also, the rate of recombination was observed to decline for mixtures with higher phase transition temperatures.	1,2-Dipalmitoylphosphatidylcholine	54-84	apolipoprotein A1	Homo sapiens	129-136
6895327-4	1981	In this report, the interactions of apolipoprotein C-II, heparin and sonicated vesicles of dipalmitoylphosphatidylcholine with purified bovine milk lipoprotein lipase were studied by gel filtration on Bio-Gel A5m.	1,2-Dipalmitoylphosphatidylcholine	91-121	apolipoprotein C2	Bos taurus	36-55
6895327-4	1981	In this report, the interactions of apolipoprotein C-II, heparin and sonicated vesicles of dipalmitoylphosphatidylcholine with purified bovine milk lipoprotein lipase were studied by gel filtration on Bio-Gel A5m.	1,2-Dipalmitoylphosphatidylcholine	91-121	lipoprotein lipase	Homo sapiens	148-166
6895327-5	1981	In the presence of vesicles of dipalmitoylphosphatidylcholine (1 mg), lipoprotein lipase (25 micrograms) associated with phospholipids even in the absence of apolipoprotein C-II.	1,2-Dipalmitoylphosphatidylcholine	31-61	lipoprotein lipase	Homo sapiens	70-88
6895182-2	1981	Human serum albumin, the purity of which was confirmed by two-dimensional gel electrophoresis and high-pressure liquid chromatography, is able to bind dipalmitoyl phosphatidylcholine and the resulting albumin-phospholipid complex can cause marked sterol release from animal and human cells in tissue culture.	1,2-Dipalmitoylphosphatidylcholine	151-182	albumin	Homo sapiens	6-19
6971831-2	1981	The reactions of the radical anions Br2- and (SCN)2- produced by pulse-radiolysis have been used to study the interaction of dipalmitoyl phosphatidyl choline vesicles with the membrane binding segment (MBS) of cytochrome b5.	1,2-Dipalmitoylphosphatidylcholine	125-157	cytochrome b5 type A	Homo sapiens	210-223
6126513-8	1982	ACAT activity was five times higher when the liposomes were prepared from dioleoylphosphatidylcholine than from saturated phosphatidylcholines, including hydrogenated egg yolk, dimyristoyl or dipalmitoyl phosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	192-223	acetyl-Coenzyme A acetyltransferase 1	Mus musculus	0-4
7104306-5	1982	The half-time for dipalmitoyl-PC exchange from HDL3 to LDL is 5 +/- h, indicating that the flux of PC is much lower than that of cholesterol.	1,2-Dipalmitoylphosphatidylcholine	18-32	HDL3	Homo sapiens	47-51
7093234-4	1982	The following results were obtained: (1) The rate of solute diffusion, which is decreased monotonically, in DMPC/DPPC MLV, by increasing the molar fractions of DPPC, exhibits maxima at 0.2 molar fraction of DSPC in DMPC/DSPC MLV and at 0.4 molar fraction of DBPC in DMPC/DBPC MLV.	1,2-Dipalmitoylphosphatidylcholine	113-117	Y-box binding protein 2	Homo sapiens	258-262
7093234-4	1982	The following results were obtained: (1) The rate of solute diffusion, which is decreased monotonically, in DMPC/DPPC MLV, by increasing the molar fractions of DPPC, exhibits maxima at 0.2 molar fraction of DSPC in DMPC/DSPC MLV and at 0.4 molar fraction of DBPC in DMPC/DBPC MLV.	1,2-Dipalmitoylphosphatidylcholine	113-117	Y-box binding protein 2	Homo sapiens	271-275
7093234-4	1982	The following results were obtained: (1) The rate of solute diffusion, which is decreased monotonically, in DMPC/DPPC MLV, by increasing the molar fractions of DPPC, exhibits maxima at 0.2 molar fraction of DSPC in DMPC/DSPC MLV and at 0.4 molar fraction of DBPC in DMPC/DBPC MLV.	1,2-Dipalmitoylphosphatidylcholine	160-164	Y-box binding protein 2	Homo sapiens	258-262
7093234-4	1982	The following results were obtained: (1) The rate of solute diffusion, which is decreased monotonically, in DMPC/DPPC MLV, by increasing the molar fractions of DPPC, exhibits maxima at 0.2 molar fraction of DSPC in DMPC/DSPC MLV and at 0.4 molar fraction of DBPC in DMPC/DBPC MLV.	1,2-Dipalmitoylphosphatidylcholine	160-164	Y-box binding protein 2	Homo sapiens	271-275
6113238-1	1981	gamma-Glutamyl transpeptidase purified from hog kidney cortex was implanted in the human erythrocyte membrane by incubation of erythrocytes at 37 degrees c with gamma-glutamyl transpeptidase-incorporated dipalmitoyl phosphatidylcholine vesicles.	1,2-Dipalmitoylphosphatidylcholine	204-235	inactive glutathione hydrolase 2	Homo sapiens	0-29
6113238-1	1981	gamma-Glutamyl transpeptidase purified from hog kidney cortex was implanted in the human erythrocyte membrane by incubation of erythrocytes at 37 degrees c with gamma-glutamyl transpeptidase-incorporated dipalmitoyl phosphatidylcholine vesicles.	1,2-Dipalmitoylphosphatidylcholine	204-235	inactive glutathione hydrolase 2	Homo sapiens	161-190
7237434-1	1981	The simultaneous administration of dipalmitoylphosphatidylcholine liposomes and methyl-bis(beta-chloroethyl)amine (HN2) to Ehrlich ascites tumor-bearing mice results in prolongation of survival, reduction of toxicity, and increase in chemotherapeutic index when compared to HN2 alone.	1,2-Dipalmitoylphosphatidylcholine	35-65	MT-RNR2 like 2 (pseudogene)	Homo sapiens	115-118
7237434-1	1981	The simultaneous administration of dipalmitoylphosphatidylcholine liposomes and methyl-bis(beta-chloroethyl)amine (HN2) to Ehrlich ascites tumor-bearing mice results in prolongation of survival, reduction of toxicity, and increase in chemotherapeutic index when compared to HN2 alone.	1,2-Dipalmitoylphosphatidylcholine	35-65	MT-RNR2 like 2 (pseudogene)	Homo sapiens	274-277
7225357-3	1981	Divalent cations bind to dipalmitoylphosphatidylcholine in the sequence Ca2+ approximately equal to Cd2+ approximately equal to Mn2+ greater than Ca2+ approximately equal to Mg2+ greater than Ba2+.	1,2-Dipalmitoylphosphatidylcholine	25-55	CD2 molecule	Homo sapiens	100-103
6893278-2	1980	Detergent-extracted cytochrome b5 (soluble aggregate) forms two types of lamellar phase with dipalmitoyl phosphatidylcholine bilayers, depending upon the incubation temperature.	1,2-Dipalmitoylphosphatidylcholine	93-124	cytochrome b5 type A	Homo sapiens	20-33
6258556-1	1980	The increase in light emission of hydroperoxide-supplemented cytochrome c observed on addition of lipid vesicles was related to the degree of unsaturation of the fatty acids of the phospholipids: dipalmitoyl phosphatidylcholine was without effect, whereas dioleoyl phosphatidylcholine and soya-bean phosphatidylcholine enhanced chemiluminescence 2- and 3-fold respectively.	1,2-Dipalmitoylphosphatidylcholine	196-227	cytochrome c, somatic	Homo sapiens	61-73
7358621-4	1980	CPY could also attack the COOH-terminus of cytochrome b5 embedded in dipalmitoyl-PC liposomes even below the phase transition temperature of the synthetic phospholipid.	1,2-Dipalmitoylphosphatidylcholine	69-83	cytochrome b5 type A	Homo sapiens	43-56
6991910-1	1980	The interaction between dipalmitoyl lecithin and egg lecithin with insulin was studied in a non-aqueous solvent such as dioxane-chloroform (1:1) by dielectric constant measurements and absorption spectra.	1,2-Dipalmitoylphosphatidylcholine	24-44	insulin	Homo sapiens	67-74
293667-1	1979	The technique of fluorescence recovery after photobleaching was used to investigate the lateral mobility of a fluorescein-labeled amphipathic apolipoprotein, ApoC-III, bound to multibilayers prepared from dipalmitoyl phosphatidylcholine, egg phosphatidylcholine, and a 1:1 (molar ratio) mixture of egg phosphatidylcholine and cholesterol.	1,2-Dipalmitoylphosphatidylcholine	205-236	apolipoprotein C3	Homo sapiens	158-166
444523-1	1979	Complexes of the B-protein of fd phage with the model lipid dipalmitoyl phosphatidylcholine (DPPC) were made by sonication of the fd phage in the presence of dipalmitoyl phosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	60-91	tyrosinase related protein 1	Homo sapiens	17-26
582173-0	1979	Action of cobra venom phospholipase A2 on the gel and liquid crystalline states of dimyristoyl and dipalmitoyl phosphatidylcholine vesicles.	1,2-Dipalmitoylphosphatidylcholine	99-130	phospholipase A2 group IB	Homo sapiens	22-38
444523-1	1979	Complexes of the B-protein of fd phage with the model lipid dipalmitoyl phosphatidylcholine (DPPC) were made by sonication of the fd phage in the presence of dipalmitoyl phosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	93-97	tyrosinase related protein 1	Homo sapiens	17-26
444523-1	1979	Complexes of the B-protein of fd phage with the model lipid dipalmitoyl phosphatidylcholine (DPPC) were made by sonication of the fd phage in the presence of dipalmitoyl phosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	158-189	tyrosinase related protein 1	Homo sapiens	17-26
856493-1	1977	A new method has been developed to improve the linearity of the plasma lecithin-cholesterol acyltransferase reaction by adding synthetic dipalmitoyl lecithin sol to the incubation medium and subsequently measuring the change in free cholesterol content after incubation by a combined enzymatic method using cholesterol oxidase and peroxidase.	1,2-Dipalmitoylphosphatidylcholine	137-157	lecithin-cholesterol acyltransferase	Homo sapiens	71-107
365254-2	1978	Rate constants and activation parameters have been determined for the transport of Pr3+ ions by the ionophore A23187 across dipalmitoyl phosphatidylcholine vesicular membranes.	1,2-Dipalmitoylphosphatidylcholine	124-155	proteinase 3	Homo sapiens	83-86
293667-2	1979	In dipalmitoyl phosphatidylcholine bilayers the lateral diffusion coefficient (D) for the protein is about 2 x 10(-9) cm(2) sec(-1) at 20 degrees C and about 9 x 10(-8) cm(2) sec(-1) at 45 degrees C. Plots of D versus temperature in this system show a transition between about 30 and 35 degrees C. Arrhenius activation energies for the diffusion in this case between 15 and 30 degrees C and between 35 and 45 degrees C are 28.5 and 7.0 kcal mol(-1), respectively (1 calorie = 4.18 joules).	1,2-Dipalmitoylphosphatidylcholine	3-34	secretory blood group 1, pseudogene	Homo sapiens	124-130
293667-2	1979	In dipalmitoyl phosphatidylcholine bilayers the lateral diffusion coefficient (D) for the protein is about 2 x 10(-9) cm(2) sec(-1) at 20 degrees C and about 9 x 10(-8) cm(2) sec(-1) at 45 degrees C. Plots of D versus temperature in this system show a transition between about 30 and 35 degrees C. Arrhenius activation energies for the diffusion in this case between 15 and 30 degrees C and between 35 and 45 degrees C are 28.5 and 7.0 kcal mol(-1), respectively (1 calorie = 4.18 joules).	1,2-Dipalmitoylphosphatidylcholine	3-34	secretory blood group 1, pseudogene	Homo sapiens	175-181
577185-1	1977	Differential scanning calorimetry (DSC) was used to detect phase separation induced by hydrophobic myelin protein, lipophilin, in a mixture of phosphatidylserine (PS) and dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	203-207	proteolipid protein 1	Homo sapiens	115-125
576871-4	1977	Analysis of lung tissue composition yielded the following results: (a) the prolactin-treated group of fetuses showed 40% higher total lung phospholipid content (17.0 +/- 0.8 micronmol/g) than the control group (12.2 +/- 0.5 micronmol/g); (b) the prolactin-treated group had a 67% higher lung lecithin content (8.7 +/- 0.8 micronmol/g) than the control group (5.2 +/- 0.4 micronmol/g); (c) dipalmitoyllecithin accounted for 67% of total lung lecithin in the prolactin-treated group and 44% in the control group.	1,2-Dipalmitoylphosphatidylcholine	389-408	prolactin	Oryctolagus cuniculus	75-84
833505-1	1977	We have studied the lipid binding of apoC-III with two types of mixed vesicles of DMPC (dimyristoyl phosphatidylcholine) and DPPC (dipalmitoyl phosphatidyl-choline).	1,2-Dipalmitoylphosphatidylcholine	125-129	apolipoprotein C3	Homo sapiens	37-45
833505-1	1977	We have studied the lipid binding of apoC-III with two types of mixed vesicles of DMPC (dimyristoyl phosphatidylcholine) and DPPC (dipalmitoyl phosphatidyl-choline).	1,2-Dipalmitoylphosphatidylcholine	131-163	apolipoprotein C3	Homo sapiens	37-45
833505-4	1977	Combining DMPC:DPPC macroscopic mixtures with apoC-III above the transition temperature, Tc 23 degrees C, of DMPC produces an isolatable complex consisting of 4:1 DMPC:DPPC.	1,2-Dipalmitoylphosphatidylcholine	168-172	apolipoprotein C3	Homo sapiens	46-54
833505-6	1977	Spectral analysis of apoC-III in the presence of the micromixtures reveals a single transition, which occurs between the respective thermal transitions of DMPC (23 degrees C) and DPPC (41 degrees C).	1,2-Dipalmitoylphosphatidylcholine	179-183	apolipoprotein C3	Homo sapiens	21-29
183811-4	1976	These results are interpreted as evidence for a phospholipid annulus of at least 30 lipid molecules with interact directly with the ATPase and cannot undergo a phase transition at 41 degrees C. This structural interaction of the ATPase with the annular DPL molecules has a predominant effect in determining the form of the temperature-activity profiles.	1,2-Dipalmitoylphosphatidylcholine	253-256	dynein axonemal heavy chain 8	Homo sapiens	132-138
183811-4	1976	These results are interpreted as evidence for a phospholipid annulus of at least 30 lipid molecules with interact directly with the ATPase and cannot undergo a phase transition at 41 degrees C. This structural interaction of the ATPase with the annular DPL molecules has a predominant effect in determining the form of the temperature-activity profiles.	1,2-Dipalmitoylphosphatidylcholine	253-256	dynein axonemal heavy chain 8	Homo sapiens	229-235
183811-0	1976	Annular lipids determine the ATPase activity of a calcium transport protein complexed with dipalmitoyllecithin.	1,2-Dipalmitoylphosphatidylcholine	91-110	dynein axonemal heavy chain 8	Homo sapiens	29-35
33737583-4	2021	In this work, we report the production and characterization of hybrid core-shell nanoparticles (hNPs) comprising a PLGA core and a dipalmitoylphosphatidylcholine (DPPC) shell engineered for inhalation.	1,2-Dipalmitoylphosphatidylcholine	131-161	neuropeptide S	Homo sapiens	96-100
183811-1	1976	Pure complexes of dipalmitoyllecithin (DPL, 16:0) which Ca2+, Mg2+ dependent ATPase from sarcoplasmic reticulum are unusual in retaining significant ATPase activity down to about 30 degrees C, well below the transition temperature of the pure lipid at 41 degrees C. A minimum of about 35 lipid molecules per ATPase is required to maintain maximal ATPase activity, but the complexes are progressively and irreversibly inactivated at lower lipid to protein ratios.	1,2-Dipalmitoylphosphatidylcholine	18-37	dynein axonemal heavy chain 8	Homo sapiens	77-83
183811-1	1976	Pure complexes of dipalmitoyllecithin (DPL, 16:0) which Ca2+, Mg2+ dependent ATPase from sarcoplasmic reticulum are unusual in retaining significant ATPase activity down to about 30 degrees C, well below the transition temperature of the pure lipid at 41 degrees C. A minimum of about 35 lipid molecules per ATPase is required to maintain maximal ATPase activity, but the complexes are progressively and irreversibly inactivated at lower lipid to protein ratios.	1,2-Dipalmitoylphosphatidylcholine	18-37	dynein axonemal heavy chain 8	Homo sapiens	149-155
183811-1	1976	Pure complexes of dipalmitoyllecithin (DPL, 16:0) which Ca2+, Mg2+ dependent ATPase from sarcoplasmic reticulum are unusual in retaining significant ATPase activity down to about 30 degrees C, well below the transition temperature of the pure lipid at 41 degrees C. A minimum of about 35 lipid molecules per ATPase is required to maintain maximal ATPase activity, but the complexes are progressively and irreversibly inactivated at lower lipid to protein ratios.	1,2-Dipalmitoylphosphatidylcholine	18-37	dynein axonemal heavy chain 8	Homo sapiens	149-155
183811-1	1976	Pure complexes of dipalmitoyllecithin (DPL, 16:0) which Ca2+, Mg2+ dependent ATPase from sarcoplasmic reticulum are unusual in retaining significant ATPase activity down to about 30 degrees C, well below the transition temperature of the pure lipid at 41 degrees C. A minimum of about 35 lipid molecules per ATPase is required to maintain maximal ATPase activity, but the complexes are progressively and irreversibly inactivated at lower lipid to protein ratios.	1,2-Dipalmitoylphosphatidylcholine	18-37	dynein axonemal heavy chain 8	Homo sapiens	149-155
183811-1	1976	Pure complexes of dipalmitoyllecithin (DPL, 16:0) which Ca2+, Mg2+ dependent ATPase from sarcoplasmic reticulum are unusual in retaining significant ATPase activity down to about 30 degrees C, well below the transition temperature of the pure lipid at 41 degrees C. A minimum of about 35 lipid molecules per ATPase is required to maintain maximal ATPase activity, but the complexes are progressively and irreversibly inactivated at lower lipid to protein ratios.	1,2-Dipalmitoylphosphatidylcholine	39-42	dynein axonemal heavy chain 8	Homo sapiens	77-83
183811-1	1976	Pure complexes of dipalmitoyllecithin (DPL, 16:0) which Ca2+, Mg2+ dependent ATPase from sarcoplasmic reticulum are unusual in retaining significant ATPase activity down to about 30 degrees C, well below the transition temperature of the pure lipid at 41 degrees C. A minimum of about 35 lipid molecules per ATPase is required to maintain maximal ATPase activity, but the complexes are progressively and irreversibly inactivated at lower lipid to protein ratios.	1,2-Dipalmitoylphosphatidylcholine	39-42	dynein axonemal heavy chain 8	Homo sapiens	149-155
183811-1	1976	Pure complexes of dipalmitoyllecithin (DPL, 16:0) which Ca2+, Mg2+ dependent ATPase from sarcoplasmic reticulum are unusual in retaining significant ATPase activity down to about 30 degrees C, well below the transition temperature of the pure lipid at 41 degrees C. A minimum of about 35 lipid molecules per ATPase is required to maintain maximal ATPase activity, but the complexes are progressively and irreversibly inactivated at lower lipid to protein ratios.	1,2-Dipalmitoylphosphatidylcholine	39-42	dynein axonemal heavy chain 8	Homo sapiens	149-155
183811-1	1976	Pure complexes of dipalmitoyllecithin (DPL, 16:0) which Ca2+, Mg2+ dependent ATPase from sarcoplasmic reticulum are unusual in retaining significant ATPase activity down to about 30 degrees C, well below the transition temperature of the pure lipid at 41 degrees C. A minimum of about 35 lipid molecules per ATPase is required to maintain maximal ATPase activity, but the complexes are progressively and irreversibly inactivated at lower lipid to protein ratios.	1,2-Dipalmitoylphosphatidylcholine	39-42	dynein axonemal heavy chain 8	Homo sapiens	149-155
134038-1	1976	Exchange of sarcoplasmic reticulum phospholipids with dipalmitoyllecithin inhibits the (Mg2+ + Ca2+)-activated ATPase activity below 40 degrees by inhibition of the decomposition of phosphoprotein intermediate.	1,2-Dipalmitoylphosphatidylcholine	54-73	dynein axonemal heavy chain 8	Homo sapiens	111-117
134038-3	1976	The inhibitory effect of dipalmitoyllecithin on ATPase activity is probably related to the viscosity of the hydrocarbon region of the membrane which inhibits the conformational change leading to calcium translocation and the eventual cleavage of phosphoprotein.	1,2-Dipalmitoylphosphatidylcholine	25-44	dynein axonemal heavy chain 8	Homo sapiens	48-54
33737583-4	2021	In this work, we report the production and characterization of hybrid core-shell nanoparticles (hNPs) comprising a PLGA core and a dipalmitoylphosphatidylcholine (DPPC) shell engineered for inhalation.	1,2-Dipalmitoylphosphatidylcholine	163-167	neuropeptide S	Homo sapiens	96-100
33002451-5	2021	We used a combination of experimental and computer simulation techniques to clarify molecular details of bee venom PLA2 interaction with lipid bilayers formed by palmitoyloleoylphosphatidylcholine or dipalmitoylphosphatidylcholine.	1,2-Dipalmitoylphosphatidylcholine	200-230	phospholipase A2 group IB	Homo sapiens	115-119
33037273-1	2020	In this work, we studied the mechanisms of classical activation and inactivation of signal transduction by the histamine H3 receptor, a 7-helix transmembrane bundle G-Protein Coupled Receptor through long-time-scale atomistic molecular dynamics simulations of the receptor embedded in a hydrated double layer of dipalmitoyl phosphatidyl choline, a zwitterionic polysaturated ordered lipid.	1,2-Dipalmitoylphosphatidylcholine	312-344	histamine receptor H3	Homo sapiens	111-132
32557766-9	2020	We found that dimeric Abeta, like monomeric one, had the ability to cause structural destabilization of DPPC membrane, which in turn might ultimately lead to cell death in an in vivo system.	1,2-Dipalmitoylphosphatidylcholine	104-108	amyloid beta precursor protein	Homo sapiens	22-27
33195825-4	2020	Through intrinsic Trp fluorescence we determined that the peptide affinity for fluid DPPC bilayers follows the decreasing order: D0W6Hya1 (+2) > W6Hya1 (+3) >> K0W6Hya1 (+4).	1,2-Dipalmitoylphosphatidylcholine	85-89	transient receptor potential cation channel subfamily C member 5	Bos taurus	18-21
32454007-10	2020	For DPPC LUVs, Tm increase 3.5  C at low and about 4.5  C at high copolymers concentration, sensed by Laurdan and DPH fluorescent probes, although the DPPC/copolymers molar ratio for Cop4 is higher than Cop3, Cop2 and Cop1.	1,2-Dipalmitoylphosphatidylcholine	4-8	COP1 E3 ubiquitin ligase	Homo sapiens	218-222
32360152-3	2020	METHODS: We performed affinity studies between DPPC and 9:1 DPPC:DPPS-proteoliposomes carrying AnxA5 and/or TNAP and different types of collagen matrix: type I, II, I + III and native collagenous extracellular matrix (ECM) produced from VSMCs with or without differentiation, to simulate ectopic calcification conditions.	1,2-Dipalmitoylphosphatidylcholine	47-51	annexin A5	Homo sapiens	95-100
32360152-3	2020	METHODS: We performed affinity studies between DPPC and 9:1 DPPC:DPPS-proteoliposomes carrying AnxA5 and/or TNAP and different types of collagen matrix: type I, II, I + III and native collagenous extracellular matrix (ECM) produced from VSMCs with or without differentiation, to simulate ectopic calcification conditions.	1,2-Dipalmitoylphosphatidylcholine	47-51	TNAP	Homo sapiens	108-112
32360152-3	2020	METHODS: We performed affinity studies between DPPC and 9:1 DPPC:DPPS-proteoliposomes carrying AnxA5 and/or TNAP and different types of collagen matrix: type I, II, I + III and native collagenous extracellular matrix (ECM) produced from VSMCs with or without differentiation, to simulate ectopic calcification conditions.	1,2-Dipalmitoylphosphatidylcholine	60-64	annexin A5	Homo sapiens	95-100
32360152-7	2020	The affinities of DPPC:DPPS-proteoliposomes were high for ECM from VSMCs with or without differentiation, underscoring a synergistic effect between AnxA5 and DPPS.	1,2-Dipalmitoylphosphatidylcholine	18-22	annexin A5	Homo sapiens	148-153
30958491-4	2019	Molecular interaction of sPLA2 (from bee venom) with the DPPC monolayer exhibited Ca2+ dependence.	1,2-Dipalmitoylphosphatidylcholine	57-61	phospholipase A2 group X	Homo sapiens	25-30
32057752-7	2020	The study of moxifloxacin-liposome complex behavior at phase transition in bilayer by DSC method revealed that in DPPC/CL2- liposomes system two microphases with different content of CL2- coexist and Mox interacts with both of these microphases resulting in the formation of two types of complexes with different structure and phase transition temperature.	1,2-Dipalmitoylphosphatidylcholine	114-118	endogenous retrovirus group W member 5	Homo sapiens	119-122
32057752-7	2020	The study of moxifloxacin-liposome complex behavior at phase transition in bilayer by DSC method revealed that in DPPC/CL2- liposomes system two microphases with different content of CL2- coexist and Mox interacts with both of these microphases resulting in the formation of two types of complexes with different structure and phase transition temperature.	1,2-Dipalmitoylphosphatidylcholine	114-118	endogenous retrovirus group W member 5	Homo sapiens	183-186
31927361-6	2020	Further experiments conducted by adding PS"s major components (dipalmitoylphosphatidylcholine, DPPC; bovine serum albumin, BSA) demonstrated that comparison of DPPC, adsorbed BSA is beneficial for the dissolution of heavy metals in smelting soot fine particles.	1,2-Dipalmitoylphosphatidylcholine	160-164	albumin	Homo sapiens	108-121
31651923-5	2019	When injected into the subphase beneath a monolayer of the phospholipid dipalmitoylphosphatidylcholine (DPPC, the majority component of LS), fibrinogen preferentially penetrates disordered liquid expanded (LE) regions and accumulates on the boundaries between LE DPPC and liquid condensed (LC) DPPC domains.	1,2-Dipalmitoylphosphatidylcholine	72-102	fibrinogen beta chain	Homo sapiens	141-151
31651923-5	2019	When injected into the subphase beneath a monolayer of the phospholipid dipalmitoylphosphatidylcholine (DPPC, the majority component of LS), fibrinogen preferentially penetrates disordered liquid expanded (LE) regions and accumulates on the boundaries between LE DPPC and liquid condensed (LC) DPPC domains.	1,2-Dipalmitoylphosphatidylcholine	104-108	fibrinogen beta chain	Homo sapiens	141-151
31651923-5	2019	When injected into the subphase beneath a monolayer of the phospholipid dipalmitoylphosphatidylcholine (DPPC, the majority component of LS), fibrinogen preferentially penetrates disordered liquid expanded (LE) regions and accumulates on the boundaries between LE DPPC and liquid condensed (LC) DPPC domains.	1,2-Dipalmitoylphosphatidylcholine	263-267	fibrinogen beta chain	Homo sapiens	141-151
31651923-5	2019	When injected into the subphase beneath a monolayer of the phospholipid dipalmitoylphosphatidylcholine (DPPC, the majority component of LS), fibrinogen preferentially penetrates disordered liquid expanded (LE) regions and accumulates on the boundaries between LE DPPC and liquid condensed (LC) DPPC domains.	1,2-Dipalmitoylphosphatidylcholine	263-267	fibrinogen beta chain	Homo sapiens	141-151
32086094-8	2020	DPPC also led to a higher level of de novo lipogenesis regulator FASN in cells exposed to hydroxylated MWCNTs, as well as a higher level of p-chop and scavenger receptor MSR1 in cells exposed to carboxylated MWCNTs.	1,2-Dipalmitoylphosphatidylcholine	0-4	fatty acid synthase	Homo sapiens	65-69
32086094-8	2020	DPPC also led to a higher level of de novo lipogenesis regulator FASN in cells exposed to hydroxylated MWCNTs, as well as a higher level of p-chop and scavenger receptor MSR1 in cells exposed to carboxylated MWCNTs.	1,2-Dipalmitoylphosphatidylcholine	0-4	macrophage scavenger receptor 1	Homo sapiens	170-174
32533571-2	2021	dipalmitoylphosphatidylcholine (DPPC) nanoparticles loaded vascular endothelial growth factor (VEGF) were produced using microfluidic platforms.	1,2-Dipalmitoylphosphatidylcholine	0-30	vascular endothelial growth factor A	Homo sapiens	59-93
32533571-2	2021	dipalmitoylphosphatidylcholine (DPPC) nanoparticles loaded vascular endothelial growth factor (VEGF) were produced using microfluidic platforms.	1,2-Dipalmitoylphosphatidylcholine	0-30	vascular endothelial growth factor A	Homo sapiens	95-99
32533571-2	2021	dipalmitoylphosphatidylcholine (DPPC) nanoparticles loaded vascular endothelial growth factor (VEGF) were produced using microfluidic platforms.	1,2-Dipalmitoylphosphatidylcholine	32-36	vascular endothelial growth factor A	Homo sapiens	59-93
32533571-2	2021	dipalmitoylphosphatidylcholine (DPPC) nanoparticles loaded vascular endothelial growth factor (VEGF) were produced using microfluidic platforms.	1,2-Dipalmitoylphosphatidylcholine	32-36	vascular endothelial growth factor A	Homo sapiens	95-99
32085611-9	2020	Thermodynamic analyses based on the measurement of surface pressure exclusion (piexc), enthalpy (DeltaH), and phase transition cooperativity (Deltat1/2) showed that AnxA6 interacted with DPPC and 9:1 DPPC:DPPS systems and that this interaction increased in the presence of Chol.	1,2-Dipalmitoylphosphatidylcholine	187-191	annexin A6	Homo sapiens	165-170
32085611-9	2020	Thermodynamic analyses based on the measurement of surface pressure exclusion (piexc), enthalpy (DeltaH), and phase transition cooperativity (Deltat1/2) showed that AnxA6 interacted with DPPC and 9:1 DPPC:DPPS systems and that this interaction increased in the presence of Chol.	1,2-Dipalmitoylphosphatidylcholine	200-204	annexin A6	Homo sapiens	165-170
32085611-11	2020	AnxA6-lipid interaction was also Ca2+-dependent, as evidenced by the increase in piexc in negatively charged 9:1 DPPC:DPPS monolayers and the decrease in DeltaH in 9:1 DPPC:DPPS proteoliposomes caused by the addition of AnxA6 in the presence of Ca2+ compared to DPPC zwitterionic bilayers.	1,2-Dipalmitoylphosphatidylcholine	113-117	annexin A6	Homo sapiens	0-5
32085611-11	2020	AnxA6-lipid interaction was also Ca2+-dependent, as evidenced by the increase in piexc in negatively charged 9:1 DPPC:DPPS monolayers and the decrease in DeltaH in 9:1 DPPC:DPPS proteoliposomes caused by the addition of AnxA6 in the presence of Ca2+ compared to DPPC zwitterionic bilayers.	1,2-Dipalmitoylphosphatidylcholine	168-172	annexin A6	Homo sapiens	0-5
32085611-11	2020	AnxA6-lipid interaction was also Ca2+-dependent, as evidenced by the increase in piexc in negatively charged 9:1 DPPC:DPPS monolayers and the decrease in DeltaH in 9:1 DPPC:DPPS proteoliposomes caused by the addition of AnxA6 in the presence of Ca2+ compared to DPPC zwitterionic bilayers.	1,2-Dipalmitoylphosphatidylcholine	168-172	annexin A6	Homo sapiens	0-5
32085611-12	2020	The interaction of AnxA6 with DPPC and 9:1 DPPC:DPPS systems was distinct even in the absence of Ca2+ as observed by the larger change in Deltat1/2 in 9:1 DPPC:DPPS vesicles as compared to DPPC vesicles.	1,2-Dipalmitoylphosphatidylcholine	30-34	annexin A6	Homo sapiens	19-24
32085611-12	2020	The interaction of AnxA6 with DPPC and 9:1 DPPC:DPPS systems was distinct even in the absence of Ca2+ as observed by the larger change in Deltat1/2 in 9:1 DPPC:DPPS vesicles as compared to DPPC vesicles.	1,2-Dipalmitoylphosphatidylcholine	43-47	annexin A6	Homo sapiens	19-24
32085611-12	2020	The interaction of AnxA6 with DPPC and 9:1 DPPC:DPPS systems was distinct even in the absence of Ca2+ as observed by the larger change in Deltat1/2 in 9:1 DPPC:DPPS vesicles as compared to DPPC vesicles.	1,2-Dipalmitoylphosphatidylcholine	43-47	annexin A6	Homo sapiens	19-24
32085611-12	2020	The interaction of AnxA6 with DPPC and 9:1 DPPC:DPPS systems was distinct even in the absence of Ca2+ as observed by the larger change in Deltat1/2 in 9:1 DPPC:DPPS vesicles as compared to DPPC vesicles.	1,2-Dipalmitoylphosphatidylcholine	43-47	annexin A6	Homo sapiens	19-24
32085611-13	2020	Protrusions on the surface of DPPC proteoliposomes observed by atomic force microscopy suggested that oligomeric AnxA6 interacted with the vesicle membrane.	1,2-Dipalmitoylphosphatidylcholine	30-34	annexin A6	Homo sapiens	113-118
32922485-3	2020	To perform this investigation, a nanoliposome composed of DPPC, DSPE-PEG2000, and DC8,9PC, was prepared as LED-sensitive systems.	1,2-Dipalmitoylphosphatidylcholine	58-62	small integral membrane protein 10 like 2A	Homo sapiens	107-110
31720452-9	2019	At pH 5.0, the interaction between DPPC and LAH increased the Tm and phase transition cooperativity showing a single lipid phase formed by hydrogen-bonded DPPC: LAH complexes.	1,2-Dipalmitoylphosphatidylcholine	35-39	desmoglein 4	Homo sapiens	44-47
31720452-9	2019	At pH 5.0, the interaction between DPPC and LAH increased the Tm and phase transition cooperativity showing a single lipid phase formed by hydrogen-bonded DPPC: LAH complexes.	1,2-Dipalmitoylphosphatidylcholine	35-39	desmoglein 4	Homo sapiens	161-164
31720452-9	2019	At pH 5.0, the interaction between DPPC and LAH increased the Tm and phase transition cooperativity showing a single lipid phase formed by hydrogen-bonded DPPC: LAH complexes.	1,2-Dipalmitoylphosphatidylcholine	155-159	desmoglein 4	Homo sapiens	44-47
31720452-9	2019	At pH 5.0, the interaction between DPPC and LAH increased the Tm and phase transition cooperativity showing a single lipid phase formed by hydrogen-bonded DPPC: LAH complexes.	1,2-Dipalmitoylphosphatidylcholine	155-159	desmoglein 4	Homo sapiens	161-164
31720452-10	2019	At pH 7.4, vesicles containing 50 mol% LAH exhibited distinct phases, ascribed to complex formation between LAH and LA or LAH and DPPC.	1,2-Dipalmitoylphosphatidylcholine	130-134	desmoglein 4	Homo sapiens	39-42
31720452-12	2019	These results provide the foundations for developing processes and products containing DPPC: LAH.	1,2-Dipalmitoylphosphatidylcholine	87-91	desmoglein 4	Homo sapiens	93-96
30958491-5	2019	DPPC molecules at the interface without Ca2+ retained a monolayer organization; upon adsorption of sPLA2 to the monolayer the packing became tighter.	1,2-Dipalmitoylphosphatidylcholine	0-4	phospholipase A2 group X	Homo sapiens	99-104
30958491-6	2019	In contrast, sPLA2-catalyzed degradation of DPPC occurred in the presence of Ca2+, leading to disruption of the ordered monolayer structure of DPPC.	1,2-Dipalmitoylphosphatidylcholine	44-48	phospholipase A2 group X	Homo sapiens	13-18
30958491-6	2019	In contrast, sPLA2-catalyzed degradation of DPPC occurred in the presence of Ca2+, leading to disruption of the ordered monolayer structure of DPPC.	1,2-Dipalmitoylphosphatidylcholine	143-147	phospholipase A2 group X	Homo sapiens	13-18
30664881-3	2019	In binary Dipalmitoylphosphatidylcholine:Cholesterol (DPPC:CHOL) mixtures, both CHOL and DPPC acyl chains were observed spontaneously entering deep "non-annular" cavities in the nAChR TMD, particularly at the subunit interface and the beta subunit center, facilitated by the low amino acid density in the cryo-EM structure of nAChR in a native membrane.	1,2-Dipalmitoylphosphatidylcholine	10-40	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	178-183
30868144-1	2019	In this study, we obtained unprecedented AFM images of the Na,K-ATPase (NKA) pump after being reconstituted into DPPC and DPPC:DPPE liposomes.	1,2-Dipalmitoylphosphatidylcholine	113-117	tachykinin precursor 1	Homo sapiens	59-70
30868144-1	2019	In this study, we obtained unprecedented AFM images of the Na,K-ATPase (NKA) pump after being reconstituted into DPPC and DPPC:DPPE liposomes.	1,2-Dipalmitoylphosphatidylcholine	113-117	tachykinin precursor 1	Homo sapiens	72-75
30868144-1	2019	In this study, we obtained unprecedented AFM images of the Na,K-ATPase (NKA) pump after being reconstituted into DPPC and DPPC:DPPE liposomes.	1,2-Dipalmitoylphosphatidylcholine	122-126	tachykinin precursor 1	Homo sapiens	59-70
30868144-1	2019	In this study, we obtained unprecedented AFM images of the Na,K-ATPase (NKA) pump after being reconstituted into DPPC and DPPC:DPPE liposomes.	1,2-Dipalmitoylphosphatidylcholine	122-126	tachykinin precursor 1	Homo sapiens	72-75
30868144-3	2019	Protrusions in the DPPC-NKA proteoliposomes ranged from 38 to 115 nm, with 74 +- 21 nm diameter and 2.1 +- 1.4 nm height.	1,2-Dipalmitoylphosphatidylcholine	19-23	tachykinin precursor 1	Homo sapiens	24-27
30868144-4	2019	DPPC:DPPE-NKA proteoliposomes showed protrusions from 21 to 78 nm, with 38 +- 16 nm diameter and 0.7 +- 0.5 nm height.	1,2-Dipalmitoylphosphatidylcholine	0-4	tachykinin precursor 1	Homo sapiens	10-13
30868144-6	2019	For DPPC-NKA proteoliposomes, we hypothesize that 40 phospholipids surround an (alphabeta)2 dimer and 46 phospholipids are present for the DPPC:DPPE-NKA proteoliposomes in an alphabeta monomer.	1,2-Dipalmitoylphosphatidylcholine	4-8	tachykinin precursor 1	Homo sapiens	9-12
30868144-6	2019	For DPPC-NKA proteoliposomes, we hypothesize that 40 phospholipids surround an (alphabeta)2 dimer and 46 phospholipids are present for the DPPC:DPPE-NKA proteoliposomes in an alphabeta monomer.	1,2-Dipalmitoylphosphatidylcholine	139-143	tachykinin precursor 1	Homo sapiens	9-12
30868144-8	2019	AFM data suggest that DPPC-NKA proteoliposomes are also rightside-out protein orientated, where the protrusions have an average height of 2.1 nm, while for DPPC:DPPE-NKA proteoliposomes, the majority of the protein reconstituted should be inside-out orientated, where the protrusions" average height is 0.5 nm.	1,2-Dipalmitoylphosphatidylcholine	22-26	tachykinin precursor 1	Homo sapiens	27-30
30868144-8	2019	AFM data suggest that DPPC-NKA proteoliposomes are also rightside-out protein orientated, where the protrusions have an average height of 2.1 nm, while for DPPC:DPPE-NKA proteoliposomes, the majority of the protein reconstituted should be inside-out orientated, where the protrusions" average height is 0.5 nm.	1,2-Dipalmitoylphosphatidylcholine	22-26	tachykinin precursor 1	Homo sapiens	166-169
30868144-8	2019	AFM data suggest that DPPC-NKA proteoliposomes are also rightside-out protein orientated, where the protrusions have an average height of 2.1 nm, while for DPPC:DPPE-NKA proteoliposomes, the majority of the protein reconstituted should be inside-out orientated, where the protrusions" average height is 0.5 nm.	1,2-Dipalmitoylphosphatidylcholine	156-160	tachykinin precursor 1	Homo sapiens	27-30
30868144-8	2019	AFM data suggest that DPPC-NKA proteoliposomes are also rightside-out protein orientated, where the protrusions have an average height of 2.1 nm, while for DPPC:DPPE-NKA proteoliposomes, the majority of the protein reconstituted should be inside-out orientated, where the protrusions" average height is 0.5 nm.	1,2-Dipalmitoylphosphatidylcholine	156-160	tachykinin precursor 1	Homo sapiens	166-169
31010668-4	2019	Our results indicate that bilayers composed of various lipids (DMPC, DPPC, and DSPC) with different thicknesses result in different orientations of the DCD oligomer when embedded in lipid bilayers.	1,2-Dipalmitoylphosphatidylcholine	69-73	dermcidin	Homo sapiens	152-155
30664881-3	2019	In binary Dipalmitoylphosphatidylcholine:Cholesterol (DPPC:CHOL) mixtures, both CHOL and DPPC acyl chains were observed spontaneously entering deep "non-annular" cavities in the nAChR TMD, particularly at the subunit interface and the beta subunit center, facilitated by the low amino acid density in the cryo-EM structure of nAChR in a native membrane.	1,2-Dipalmitoylphosphatidylcholine	54-58	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	178-183
30664881-3	2019	In binary Dipalmitoylphosphatidylcholine:Cholesterol (DPPC:CHOL) mixtures, both CHOL and DPPC acyl chains were observed spontaneously entering deep "non-annular" cavities in the nAChR TMD, particularly at the subunit interface and the beta subunit center, facilitated by the low amino acid density in the cryo-EM structure of nAChR in a native membrane.	1,2-Dipalmitoylphosphatidylcholine	54-58	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	326-331
30664881-3	2019	In binary Dipalmitoylphosphatidylcholine:Cholesterol (DPPC:CHOL) mixtures, both CHOL and DPPC acyl chains were observed spontaneously entering deep "non-annular" cavities in the nAChR TMD, particularly at the subunit interface and the beta subunit center, facilitated by the low amino acid density in the cryo-EM structure of nAChR in a native membrane.	1,2-Dipalmitoylphosphatidylcholine	89-93	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	178-183
30664881-3	2019	In binary Dipalmitoylphosphatidylcholine:Cholesterol (DPPC:CHOL) mixtures, both CHOL and DPPC acyl chains were observed spontaneously entering deep "non-annular" cavities in the nAChR TMD, particularly at the subunit interface and the beta subunit center, facilitated by the low amino acid density in the cryo-EM structure of nAChR in a native membrane.	1,2-Dipalmitoylphosphatidylcholine	89-93	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	326-331
31079989-5	2019	DPPC liposomes (LPs) are designed to carry glia cell line-derived neurotrophic factor (GDNF) plasmid DNA (GDNFp) to form a GDNFp-liposome (GDNFp-LPs) complex.	1,2-Dipalmitoylphosphatidylcholine	0-4	glial cell line derived neurotrophic factor	Mus musculus	43-85
30729964-8	2019	It was found that the addition of BaP has a destabilizing effect on the mixed DPPC/DPPG monolayer, manifested by the decrease in surface pressure.	1,2-Dipalmitoylphosphatidylcholine	78-82	prohibitin 2	Homo sapiens	34-37
31079989-5	2019	DPPC liposomes (LPs) are designed to carry glia cell line-derived neurotrophic factor (GDNF) plasmid DNA (GDNFp) to form a GDNFp-liposome (GDNFp-LPs) complex.	1,2-Dipalmitoylphosphatidylcholine	0-4	glial cell line derived neurotrophic factor	Mus musculus	87-91
30429447-1	2018	The effect of beta-sitosteryl sulfate (PSO4) on the liposomal size, stability, fluidity, and dispersibility of DPPC liposomes prepared by vortex mixing, bath-sonication, and probe-sonication has been studied.	1,2-Dipalmitoylphosphatidylcholine	111-115	pre-mRNA processing factor 19	Homo sapiens	39-43
30429447-6	2018	PSO4 improves the dispersibility of the DPPC liposomes and enhances their hydration.	1,2-Dipalmitoylphosphatidylcholine	40-44	pre-mRNA processing factor 19	Homo sapiens	0-4
29028602-6	2017	Co-exposure of A549 cells or A549 epithelium model to DPPC and ZnO NPs induced a higher release of lactate dehydrogenase (LDH) and interleukin-6 (IL-6) compared with the exposure of ZnO NPs alone.	1,2-Dipalmitoylphosphatidylcholine	54-58	interleukin 6	Homo sapiens	131-144
29499181-5	2018	Long-tailed analogues (C16, C18) are cohesively integrated into DPPC monolayers due to their smaller cone angles at the interfacial region and increased hydrocarbon compatibility in the hydrophobic region.	1,2-Dipalmitoylphosphatidylcholine	64-68	Bardet-Biedl syndrome 9	Homo sapiens	28-31
29760327-1	2018	We investigated the hydration behavior of dipalmitoylphosphatidylcholine (DPPC) bilayers containing sodium beta-sitosteryl sulfate (PSO4).	1,2-Dipalmitoylphosphatidylcholine	42-72	pre-mRNA processing factor 19	Homo sapiens	132-136
29760327-2	2018	PSO4 was found to enhance hydration in the headgroup region of DPPC bilayers.	1,2-Dipalmitoylphosphatidylcholine	63-67	pre-mRNA processing factor 19	Homo sapiens	0-4
29760327-3	2018	Therefore, with the incorporation of PSO4 into DPPC membranes, the amount of water required to reach the fully hydrated state was enhanced as indicated by the constant values of the main phase transition temperature (Tm) and the bilayer repeat distance (d).	1,2-Dipalmitoylphosphatidylcholine	47-51	pre-mRNA processing factor 19	Homo sapiens	37-41
29760327-4	2018	For example, with the addition of 20 mol% of PSO4, the saturation point was shifted to ~70 wt% water compared to ~40 wt% for pure DPPC and 47 wt% for DPPC-cholesterol.	1,2-Dipalmitoylphosphatidylcholine	130-134	pre-mRNA processing factor 19	Homo sapiens	45-49
29526873-4	2018	PSO4 was less miscible in DSPC than in a dipalmitoylphosphatidylcholine (DPPC) membrane, as evidenced by its tendency to separate from the bilayer at a concentration of 50 mol%.	1,2-Dipalmitoylphosphatidylcholine	41-71	pre-mRNA processing factor 19	Homo sapiens	0-4
29526873-4	2018	PSO4 was less miscible in DSPC than in a dipalmitoylphosphatidylcholine (DPPC) membrane, as evidenced by its tendency to separate from the bilayer at a concentration of 50 mol%.	1,2-Dipalmitoylphosphatidylcholine	73-77	pre-mRNA processing factor 19	Homo sapiens	0-4
29618528-5	2018	By contrast, how effectively a pre-existing DPPC monolayer prevents fibrinogen adsorption depends upon its surface pressure.	1,2-Dipalmitoylphosphatidylcholine	44-48	fibrinogen beta chain	Homo sapiens	68-78
29618528-6	2018	At low DPPC surface pressures, fibrinogen penetrates DPPC monolayers, imparting a mixed viscoelastic shear response.	1,2-Dipalmitoylphosphatidylcholine	7-11	fibrinogen beta chain	Homo sapiens	31-41
29618528-6	2018	At low DPPC surface pressures, fibrinogen penetrates DPPC monolayers, imparting a mixed viscoelastic shear response.	1,2-Dipalmitoylphosphatidylcholine	53-57	fibrinogen beta chain	Homo sapiens	31-41
29434596-5	2018	Molecular dynamics simulations revealed that PIP2 creates a stable microdomain in a dipalmitoylphosphatidylcholine bilayer, providing TIRAP with its physiologically relevant orientation.	1,2-Dipalmitoylphosphatidylcholine	84-114	TIR domain containing adaptor protein	Homo sapiens	134-139
29325469-4	2018	This review focuses on the development and recent update of an innovative TSL formulation, HaT-liposomes composed of DPPC and Brij78.	1,2-Dipalmitoylphosphatidylcholine	117-121	TSL	Homo sapiens	74-77
29428499-5	2018	At neutral pH, the tilt angle and insertion depth of hIAPP protofibrils at a DPPG bilayer reach ~52  and ~1.62 nm with respect to the membrane surface, while they become ~77  and ~1.75 nm at a mixed DPPC/DPPG membrane.	1,2-Dipalmitoylphosphatidylcholine	199-203	islet amyloid polypeptide	Homo sapiens	53-58
29371621-6	2018	Most importantly, based on the simulation observation that resveratrol has a high probability of forming hydrogen bonds with sn-1 and sn-2 ester groups, we discovered a new mechanism using experimental approach, in which resveratrol protects both sn-1 and sn-2 ester bonds of DPPC and distearoyl phosphatidylcholine (DSPC) from phospholipase A1 (PLA1) and phospholipase A2 (PLA2) cleavage.	1,2-Dipalmitoylphosphatidylcholine	276-280	lipase H	Homo sapiens	328-344
29371621-6	2018	Most importantly, based on the simulation observation that resveratrol has a high probability of forming hydrogen bonds with sn-1 and sn-2 ester groups, we discovered a new mechanism using experimental approach, in which resveratrol protects both sn-1 and sn-2 ester bonds of DPPC and distearoyl phosphatidylcholine (DSPC) from phospholipase A1 (PLA1) and phospholipase A2 (PLA2) cleavage.	1,2-Dipalmitoylphosphatidylcholine	276-280	POU class 2 homeobox 3	Homo sapiens	346-350
29371621-6	2018	Most importantly, based on the simulation observation that resveratrol has a high probability of forming hydrogen bonds with sn-1 and sn-2 ester groups, we discovered a new mechanism using experimental approach, in which resveratrol protects both sn-1 and sn-2 ester bonds of DPPC and distearoyl phosphatidylcholine (DSPC) from phospholipase A1 (PLA1) and phospholipase A2 (PLA2) cleavage.	1,2-Dipalmitoylphosphatidylcholine	276-280	phospholipase A2 group IB	Homo sapiens	356-372
29371621-6	2018	Most importantly, based on the simulation observation that resveratrol has a high probability of forming hydrogen bonds with sn-1 and sn-2 ester groups, we discovered a new mechanism using experimental approach, in which resveratrol protects both sn-1 and sn-2 ester bonds of DPPC and distearoyl phosphatidylcholine (DSPC) from phospholipase A1 (PLA1) and phospholipase A2 (PLA2) cleavage.	1,2-Dipalmitoylphosphatidylcholine	276-280	phospholipase A2 group IIA	Homo sapiens	374-378
29128360-7	2018	GOLGA2 knockout mice clearly demonstrated fibrosis features such as autophagy-activated cells, densely packed hepatocytes, increase of alveolar macrophages, and decrease of alveolar surfactant lipids (dipalmitoylphosphatidylcholine).	1,2-Dipalmitoylphosphatidylcholine	201-231	golgi autoantigen, golgin subfamily a, 2	Mus musculus	0-6
29040835-1	2018	We have studied the phase behavior of dipalmitoylphosphatidylcholine (DPPC) containing sodium beta-sitosteryl sulfate (PSO4).	1,2-Dipalmitoylphosphatidylcholine	38-68	pre-mRNA processing factor 19	Homo sapiens	119-123
29040835-2	2018	PSO4 was found to lower the phase transition temperature of DPPC to a higher degree than cholesterol or beta-sitosterol.	1,2-Dipalmitoylphosphatidylcholine	60-64	pre-mRNA processing factor 19	Homo sapiens	0-4
29028602-6	2017	Co-exposure of A549 cells or A549 epithelium model to DPPC and ZnO NPs induced a higher release of lactate dehydrogenase (LDH) and interleukin-6 (IL-6) compared with the exposure of ZnO NPs alone.	1,2-Dipalmitoylphosphatidylcholine	54-58	interleukin 6	Homo sapiens	146-150
28872861-1	2017	The N-terminal 25 amino-acid residues of pulmonary surfactant protein B (SP-B1-25) induces unusual lipid polymorphisms in a model lipid system, 4:1 DPPC/POPG, mirroring the lipid composition of native pulmonary surfactant.	1,2-Dipalmitoylphosphatidylcholine	148-152	FtsJ RNA 2'-O-methyltransferase 1	Homo sapiens	73-78
28689439-0	2017	Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary absorption of encapsulated insulin compared with co-administered insulin.	1,2-Dipalmitoylphosphatidylcholine	27-58	insulin	Homo sapiens	104-111
28689439-1	2017	OBJECTIVE: We have previously shown that aerosolized liposomes with dipalmitoyl phosphatidylcholine (DPPC) enhance the pulmonary absorption of encapsulated insulin.	1,2-Dipalmitoylphosphatidylcholine	68-99	insulin	Homo sapiens	156-163
28689439-1	2017	OBJECTIVE: We have previously shown that aerosolized liposomes with dipalmitoyl phosphatidylcholine (DPPC) enhance the pulmonary absorption of encapsulated insulin.	1,2-Dipalmitoylphosphatidylcholine	101-105	insulin	Homo sapiens	156-163
28689439-6	2017	RESULTS: DPPC liposomes enhanced the pulmonary absorption of unencapsulated free insulin; however, the enhancing effect was lower than that of the DPPC liposomes encapsulating insulin.	1,2-Dipalmitoylphosphatidylcholine	9-13	insulin	Homo sapiens	81-88
28689439-7	2017	The mechanism of the pulmonary absorption of unencapsulated free insulin by DPPC liposomes involved the opening of epithelial cell space in alveolar mucosa, and not mucosal cell damage, similar to that of the DPPC liposomes encapsulating insulin.	1,2-Dipalmitoylphosphatidylcholine	76-80	insulin	Homo sapiens	65-72
28689439-7	2017	The mechanism of the pulmonary absorption of unencapsulated free insulin by DPPC liposomes involved the opening of epithelial cell space in alveolar mucosa, and not mucosal cell damage, similar to that of the DPPC liposomes encapsulating insulin.	1,2-Dipalmitoylphosphatidylcholine	76-80	insulin	Homo sapiens	238-245
28689439-7	2017	The mechanism of the pulmonary absorption of unencapsulated free insulin by DPPC liposomes involved the opening of epithelial cell space in alveolar mucosa, and not mucosal cell damage, similar to that of the DPPC liposomes encapsulating insulin.	1,2-Dipalmitoylphosphatidylcholine	209-213	insulin	Homo sapiens	65-72
28689439-9	2017	These findings suggest that, although unencapsulated free insulin spreads throughout the alveolar mucus layer, the concentration of insulin released near the absorption surface is increased by the encapsulation of insulin into DPPC liposomes and the absorption efficiency is also increased.	1,2-Dipalmitoylphosphatidylcholine	227-231	insulin	Homo sapiens	132-139
28689439-9	2017	These findings suggest that, although unencapsulated free insulin spreads throughout the alveolar mucus layer, the concentration of insulin released near the absorption surface is increased by the encapsulation of insulin into DPPC liposomes and the absorption efficiency is also increased.	1,2-Dipalmitoylphosphatidylcholine	227-231	insulin	Homo sapiens	132-139
28689439-10	2017	CONCLUSION: We revealed that the encapsulation of insulin into DPPC liposomes is more effective for pulmonary insulin absorption than co-administration of DPPC liposomes and unencapsulated free insulin.	1,2-Dipalmitoylphosphatidylcholine	63-67	insulin	Homo sapiens	50-57
28689439-10	2017	CONCLUSION: We revealed that the encapsulation of insulin into DPPC liposomes is more effective for pulmonary insulin absorption than co-administration of DPPC liposomes and unencapsulated free insulin.	1,2-Dipalmitoylphosphatidylcholine	63-67	insulin	Homo sapiens	110-117
28872861-3	2017	Here, we characterize in detail the phase behavior of DPPC and POPG in hydrated lipid assemblies containing therapeutic levels of SP-B1-25 using 2H and 31P solid state NMR spectroscopy.	1,2-Dipalmitoylphosphatidylcholine	54-58	FtsJ RNA 2'-O-methyltransferase 1	Homo sapiens	130-135
28342211-0	2017	The molecular behavior of a single beta-amyloid inside a dipalmitoylphosphatidylcholine bilayer at three different temperatures: An atomistic simulation study: Abeta interaction with DPPC: Atomistic simulation.	1,2-Dipalmitoylphosphatidylcholine	183-187	amyloid beta precursor protein	Homo sapiens	160-165
28834721-4	2017	Our results show that SP-C induces phase segregation at 37 C, resulting in an ordered phase with spectral features resembling an interdigitated state enriched in dipalmitoylphosphatidylcholine, a liquid-crystalline bilayer phase, and an extremely mobile phase consistent with small vesicles or micelles.	1,2-Dipalmitoylphosphatidylcholine	162-192	surfactant protein C	Homo sapiens	22-26
28719181-3	2017	SP-A binds to dipalmitoylphosphatidylcholine (DPPC), the major surfactant lipid component, but not phosphatidylinositol (PI), whereas SP-D shows the opposite preference.	1,2-Dipalmitoylphosphatidylcholine	14-44	surfactant protein A1	Homo sapiens	0-4
28719181-3	2017	SP-A binds to dipalmitoylphosphatidylcholine (DPPC), the major surfactant lipid component, but not phosphatidylinositol (PI), whereas SP-D shows the opposite preference.	1,2-Dipalmitoylphosphatidylcholine	46-50	surfactant protein A1	Homo sapiens	0-4
28725182-2	2017	Furthermore, we identified phosphocholine (PC) and dipalmitoylphosphatidylcholine (DPPC) as novel nicotinic agonists that elicit metabotropic activity at monocytic nAChR.	1,2-Dipalmitoylphosphatidylcholine	51-81	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	164-169
28725182-2	2017	Furthermore, we identified phosphocholine (PC) and dipalmitoylphosphatidylcholine (DPPC) as novel nicotinic agonists that elicit metabotropic activity at monocytic nAChR.	1,2-Dipalmitoylphosphatidylcholine	83-87	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	164-169
28404637-10	2017	In conclusion, the surfactant constituent, DPPC, efficiently inhibits ATP-induced inflammasome activation and maturation of IL-1beta in human monocytes by a mechanism involving nAChRs.	1,2-Dipalmitoylphosphatidylcholine	43-47	interleukin 1 beta	Homo sapiens	124-132
27629593-7	2017	LPCAT1 is a key enzyme in the synthesis of PAF, as well as DPPC, a highly surface-active glycerophospholipid component of surfactant.	1,2-Dipalmitoylphosphatidylcholine	59-63	lysophosphatidylcholine acyltransferase 1	Homo sapiens	0-6
28381774-4	2017	The excess Gibbs free energy of mixing and two-dimensional phase diagrams suggest that CnBP(FC14)2 is miscible with DPPC monolayers and also has a fluidizing effect on DPPC monolayers.	1,2-Dipalmitoylphosphatidylcholine	116-120	CCHC-type zinc finger nucleic acid binding protein	Homo sapiens	87-91
28381774-4	2017	The excess Gibbs free energy of mixing and two-dimensional phase diagrams suggest that CnBP(FC14)2 is miscible with DPPC monolayers and also has a fluidizing effect on DPPC monolayers.	1,2-Dipalmitoylphosphatidylcholine	168-172	CCHC-type zinc finger nucleic acid binding protein	Homo sapiens	87-91
27865984-2	2017	We report that a hybrid liposome composed of phospholipid (DPPC) and PEGylated block-copolymer (Poloxamer 188) can rapidly release an encapsulated hydrophilic drug in the presence of PLA2.	1,2-Dipalmitoylphosphatidylcholine	59-63	phospholipase A2 group IB	Homo sapiens	183-187
27865984-3	2017	DPPC/P188 liposomes released approximately 80% of the encapsulated calcein (a fluorescence marker) within 10min in the presence of 120 mU of PLA2 at 37 C in vitro, whereas several other liposomal compositions used for inhalation therapy did not.	1,2-Dipalmitoylphosphatidylcholine	0-4	phospholipase A2 group IB	Homo sapiens	141-145
27865984-4	2017	DPPC/P188 liposomes were stable in the absence of PLA2 at 37 C after 60min incubation and drug release by PLA2 was dependent on the amount of P188 incorporated into the DPPC liposomes.	1,2-Dipalmitoylphosphatidylcholine	0-4	phospholipase A2 group IB	Homo sapiens	106-110
27865984-4	2017	DPPC/P188 liposomes were stable in the absence of PLA2 at 37 C after 60min incubation and drug release by PLA2 was dependent on the amount of P188 incorporated into the DPPC liposomes.	1,2-Dipalmitoylphosphatidylcholine	169-173	phospholipase A2 group IB	Homo sapiens	106-110
27865984-5	2017	Drug release from doxorubicin (DOX, anticancer drug)-loaded DPPC/P188 liposomes was facilitated at higher PLA2 concentrations and was dependent on the temperature and the presence of calcium ion, thus partially explaining PLA2-responsive drug release.	1,2-Dipalmitoylphosphatidylcholine	60-64	phospholipase A2 group IB	Homo sapiens	106-110
27865984-5	2017	Drug release from doxorubicin (DOX, anticancer drug)-loaded DPPC/P188 liposomes was facilitated at higher PLA2 concentrations and was dependent on the temperature and the presence of calcium ion, thus partially explaining PLA2-responsive drug release.	1,2-Dipalmitoylphosphatidylcholine	60-64	phospholipase A2 group IB	Homo sapiens	222-226
27865984-7	2017	These findings suggest that DPPC/P188 liposomes are a promising drug carrier for delivering drug efficiently at PLA2-expressing sites such as inflammatory lung cancer.	1,2-Dipalmitoylphosphatidylcholine	28-32	phospholipase A2 group IB	Homo sapiens	112-116
27713745-2	2016	Recently, we demonstrated that B-1 cells produce dipalmitoyl-phosphatidylcholine (DPPC)-specific IgM upon immunization of BALB/c mice with DPPC-liposomes encapsulating ovalbumin (OVA).	1,2-Dipalmitoylphosphatidylcholine	49-80	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	168-177
27926847-4	2016	In this study, we used coarse-grained molecular dynamics to characterize a dipalmitoylphosphatidylcholine bilayer system under ionic imbalances ranging from 0 to ~0.06 e charges per lipid (e/Lip).	1,2-Dipalmitoylphosphatidylcholine	75-105	SMG1 nonsense mediated mRNA decay associated PI3K related kinase	Homo sapiens	191-194
27713745-2	2016	Recently, we demonstrated that B-1 cells produce dipalmitoyl-phosphatidylcholine (DPPC)-specific IgM upon immunization of BALB/c mice with DPPC-liposomes encapsulating ovalbumin (OVA).	1,2-Dipalmitoylphosphatidylcholine	49-80	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	179-182
27713745-2	2016	Recently, we demonstrated that B-1 cells produce dipalmitoyl-phosphatidylcholine (DPPC)-specific IgM upon immunization of BALB/c mice with DPPC-liposomes encapsulating ovalbumin (OVA).	1,2-Dipalmitoylphosphatidylcholine	82-86	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	168-177
27713745-2	2016	Recently, we demonstrated that B-1 cells produce dipalmitoyl-phosphatidylcholine (DPPC)-specific IgM upon immunization of BALB/c mice with DPPC-liposomes encapsulating ovalbumin (OVA).	1,2-Dipalmitoylphosphatidylcholine	82-86	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	179-182
27713745-2	2016	Recently, we demonstrated that B-1 cells produce dipalmitoyl-phosphatidylcholine (DPPC)-specific IgM upon immunization of BALB/c mice with DPPC-liposomes encapsulating ovalbumin (OVA).	1,2-Dipalmitoylphosphatidylcholine	139-143	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	168-177
27713745-2	2016	Recently, we demonstrated that B-1 cells produce dipalmitoyl-phosphatidylcholine (DPPC)-specific IgM upon immunization of BALB/c mice with DPPC-liposomes encapsulating ovalbumin (OVA).	1,2-Dipalmitoylphosphatidylcholine	139-143	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	179-182
27713745-8	2016	In conclusion, in the present work, it has been demonstrated that phosphocholine-specific antibodies improve T-dependent antibody responses against OVA carried by DPPC-liposomes.	1,2-Dipalmitoylphosphatidylcholine	163-167	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	148-151
26855469-1	2016	After an hour contact with a phospholipase A2 (PLA2) solution, only the outer leaflet of the dipalmitoylphosphatidylcholine (DPPC) bilayers supported on mica surface underwent hydrolysis whose products, i.e., palmitic acid and lysophospholipid, accumulated on the bilayer surface.	1,2-Dipalmitoylphosphatidylcholine	93-123	phospholipase A2 group IB	Homo sapiens	29-45
27324153-2	2016	Bifunctional avidity of SP-A for pathogen-associated molecular patterns (PAMPs) such as lipid A and for dipalmitoylphosphatidylcholine (DPPC), the major component of surfactant membranes lining the air-liquid interface of the lung, ensures that the protein is poised for first-line interactions with inhaled pathogens.	1,2-Dipalmitoylphosphatidylcholine	104-134	surfactant protein A1	Homo sapiens	24-28
27324153-2	2016	Bifunctional avidity of SP-A for pathogen-associated molecular patterns (PAMPs) such as lipid A and for dipalmitoylphosphatidylcholine (DPPC), the major component of surfactant membranes lining the air-liquid interface of the lung, ensures that the protein is poised for first-line interactions with inhaled pathogens.	1,2-Dipalmitoylphosphatidylcholine	136-140	surfactant protein A1	Homo sapiens	24-28
27324153-3	2016	To improve our understanding of the motifs that are required for interactions with microbes and surfactant structures, we explored the role of the tyrosine-rich binding surface on the carbohydrate recognition domain of SP-A in the interaction with DPPC and lipid A using crystallography, site-directed mutagenesis, and molecular dynamics simulations.	1,2-Dipalmitoylphosphatidylcholine	248-252	surfactant protein A1	Homo sapiens	219-223
27324153-7	2016	These results suggest that the differential binding properties of SP-A favor transfer of the protein from surfactant DPPC to pathogen membranes containing appropriate lipid PAMPs to effect key host defense functions.	1,2-Dipalmitoylphosphatidylcholine	117-121	surfactant protein A1	Homo sapiens	66-70
27280363-2	2016	In this study, the stability and release properties of dipalmitoylglycerophosphocholine (DPPC)-based liposomes incorporating the commonly used lysophosphatidylocholine (lyso-PC), and a series of monoalkyl chain ether-linked phosphatidylcholine, i.e., the biologically relevant monoalkyl chain platelet activating factor (PAF) and its derivatives lyso-PAF and methyl-PAF, were investigated.	1,2-Dipalmitoylphosphatidylcholine	89-93	PCNA clamp associated factor	Homo sapiens	321-324
27280363-2	2016	In this study, the stability and release properties of dipalmitoylglycerophosphocholine (DPPC)-based liposomes incorporating the commonly used lysophosphatidylocholine (lyso-PC), and a series of monoalkyl chain ether-linked phosphatidylcholine, i.e., the biologically relevant monoalkyl chain platelet activating factor (PAF) and its derivatives lyso-PAF and methyl-PAF, were investigated.	1,2-Dipalmitoylphosphatidylcholine	89-93	PCNA clamp associated factor	Homo sapiens	351-354
27280363-2	2016	In this study, the stability and release properties of dipalmitoylglycerophosphocholine (DPPC)-based liposomes incorporating the commonly used lysophosphatidylocholine (lyso-PC), and a series of monoalkyl chain ether-linked phosphatidylcholine, i.e., the biologically relevant monoalkyl chain platelet activating factor (PAF) and its derivatives lyso-PAF and methyl-PAF, were investigated.	1,2-Dipalmitoylphosphatidylcholine	89-93	PCNA clamp associated factor	Homo sapiens	351-354
26373704-2	2016	It was reported that NGR-modified stealth liposomes (NGR-SL) could be prepared with different lipid composition, such as 1,2-dipalmitoyl-sn-glycero-phosphatidylcholine (DPPC), hydrogenated soy posphatidylcholine (HSPC) and soy posphatidylcholine (SPC).	1,2-Dipalmitoylphosphatidylcholine	169-173	reticulon 4 receptor	Homo sapiens	21-24
26373704-2	2016	It was reported that NGR-modified stealth liposomes (NGR-SL) could be prepared with different lipid composition, such as 1,2-dipalmitoyl-sn-glycero-phosphatidylcholine (DPPC), hydrogenated soy posphatidylcholine (HSPC) and soy posphatidylcholine (SPC).	1,2-Dipalmitoylphosphatidylcholine	169-173	reticulon 4 receptor	Homo sapiens	53-56
26373704-3	2016	In the present study, NGR-modified liposomes were prepared with DPPC, HSPC, SPC or the mixture of HSPC and SPC.	1,2-Dipalmitoylphosphatidylcholine	64-68	reticulon 4 receptor	Homo sapiens	22-25
26887439-5	2016	An RNA interference screen of lipid-metabolizing enzymes revealed that lysophosphatidylcholine acyltransferase 1 (LPCAT1) was involved in the DPPC production.	1,2-Dipalmitoylphosphatidylcholine	142-146	lysophosphatidylcholine acyltransferase 1	Mus musculus	71-112
26887439-5	2016	An RNA interference screen of lipid-metabolizing enzymes revealed that lysophosphatidylcholine acyltransferase 1 (LPCAT1) was involved in the DPPC production.	1,2-Dipalmitoylphosphatidylcholine	142-146	lysophosphatidylcholine acyltransferase 1	Mus musculus	114-120
26887439-9	2016	In LPCAT1 knockout mice, DPPC level was reduced and UPR was activated in the retina.	1,2-Dipalmitoylphosphatidylcholine	25-29	lysophosphatidylcholine acyltransferase 1	Mus musculus	3-9
26921317-8	2016	The content of total phospholipid, PC, and disaturated PC in lung tissue homogenate, bronchoalveolar lavage fluid, and lung LB was increased significantly in Prdx6-S32T mutant lungs, whereas degradation of internalized [(3)H]dipalmitoyl-PC was significantly decreased.	1,2-Dipalmitoylphosphatidylcholine	225-239	peroxiredoxin 6	Mus musculus	158-163
26830860-6	2016	A linear incorporation of labeled fatty acyl CoA into dipalmitoyl phosphatidylcholine (PC) indicated that LPC generated by Prdx6 PLA2activity remained bound to the enzyme for the reacylation reaction.	1,2-Dipalmitoylphosphatidylcholine	54-85	peroxiredoxin 6	Mus musculus	123-128
26830860-6	2016	A linear incorporation of labeled fatty acyl CoA into dipalmitoyl phosphatidylcholine (PC) indicated that LPC generated by Prdx6 PLA2activity remained bound to the enzyme for the reacylation reaction.	1,2-Dipalmitoylphosphatidylcholine	54-85	phospholipase A2, group V	Mus musculus	129-133
26624532-0	2016	Surface interactions, thermodynamics and topography of binary monolayers of Insulin with dipalmitoylphosphatidylcholine and 1-palmitoyl-2-oleoylphosphatidylcholine at the air/water interface.	1,2-Dipalmitoylphosphatidylcholine	89-119	insulin	Homo sapiens	76-83
26624532-4	2016	Below 20mN/m Insulin forms stable homogenous films with DPPC and POPC at all mole fractions studied (except for films with XINS=0.05 at 10mN/m where domain coexistence was observed).	1,2-Dipalmitoylphosphatidylcholine	56-60	insulin	Homo sapiens	13-20
26624532-7	2016	The spontaneously unfavorable interactions of Insulin with DPPC are driven by favorable enthalpy that is overcome by unfavorable entropic ordering; in films with POPC both the enthalpic and entropic effects are unfavorable.	1,2-Dipalmitoylphosphatidylcholine	59-63	insulin	Homo sapiens	46-53
26592318-7	2016	The NR data suggests that in addition to penetrating into the monolayers, both LL37 and LFb formed a non-interacting layer below the LPS/DPPC monolayer.	1,2-Dipalmitoylphosphatidylcholine	137-141	cathelicidin antimicrobial peptide	Homo sapiens	79-83
26855469-1	2016	After an hour contact with a phospholipase A2 (PLA2) solution, only the outer leaflet of the dipalmitoylphosphatidylcholine (DPPC) bilayers supported on mica surface underwent hydrolysis whose products, i.e., palmitic acid and lysophospholipid, accumulated on the bilayer surface.	1,2-Dipalmitoylphosphatidylcholine	93-123	phospholipase A2 group IB	Homo sapiens	47-51
26855469-1	2016	After an hour contact with a phospholipase A2 (PLA2) solution, only the outer leaflet of the dipalmitoylphosphatidylcholine (DPPC) bilayers supported on mica surface underwent hydrolysis whose products, i.e., palmitic acid and lysophospholipid, accumulated on the bilayer surface.	1,2-Dipalmitoylphosphatidylcholine	125-129	phospholipase A2 group IB	Homo sapiens	29-45
26855469-1	2016	After an hour contact with a phospholipase A2 (PLA2) solution, only the outer leaflet of the dipalmitoylphosphatidylcholine (DPPC) bilayers supported on mica surface underwent hydrolysis whose products, i.e., palmitic acid and lysophospholipid, accumulated on the bilayer surface.	1,2-Dipalmitoylphosphatidylcholine	125-129	phospholipase A2 group IB	Homo sapiens	47-51
26397014-4	2015	In this work, the conformational behavior of both the acylated and deacylated SP-C isoforms was studied in a DPPC bilayer under different pH conditions using constant-pH molecular dynamics simulations.	1,2-Dipalmitoylphosphatidylcholine	109-113	surfactant protein C	Homo sapiens	78-82
26632402-4	2016	The new synthetic SP-C PS (sSP-C PS) was synthesized from SPa-C, dipalmitoyl phosphatidylcholine, phosphatidyl glycerol, and palmitic acid.	1,2-Dipalmitoylphosphatidylcholine	65-96	surfactant protein C	Homo sapiens	18-22
26325078-1	2015	We describe the production of stable DPPC and DPPC:DPPS-proteoliposomes harboring annexin V (AnxA5) and tissue-nonspecific alkaline phosphatase (TNAP) and their use to investigate whether the presence of AnxA5 impacts the kinetic parameters for hydrolysis of TNAP substrates at physiological pH.	1,2-Dipalmitoylphosphatidylcholine	37-41	annexin A5	Homo sapiens	82-91
26325078-1	2015	We describe the production of stable DPPC and DPPC:DPPS-proteoliposomes harboring annexin V (AnxA5) and tissue-nonspecific alkaline phosphatase (TNAP) and their use to investigate whether the presence of AnxA5 impacts the kinetic parameters for hydrolysis of TNAP substrates at physiological pH.	1,2-Dipalmitoylphosphatidylcholine	37-41	annexin A5	Homo sapiens	93-98
26325078-1	2015	We describe the production of stable DPPC and DPPC:DPPS-proteoliposomes harboring annexin V (AnxA5) and tissue-nonspecific alkaline phosphatase (TNAP) and their use to investigate whether the presence of AnxA5 impacts the kinetic parameters for hydrolysis of TNAP substrates at physiological pH.	1,2-Dipalmitoylphosphatidylcholine	46-50	annexin A5	Homo sapiens	82-91
26325078-1	2015	We describe the production of stable DPPC and DPPC:DPPS-proteoliposomes harboring annexin V (AnxA5) and tissue-nonspecific alkaline phosphatase (TNAP) and their use to investigate whether the presence of AnxA5 impacts the kinetic parameters for hydrolysis of TNAP substrates at physiological pH.	1,2-Dipalmitoylphosphatidylcholine	46-50	annexin A5	Homo sapiens	93-98
26325078-1	2015	We describe the production of stable DPPC and DPPC:DPPS-proteoliposomes harboring annexin V (AnxA5) and tissue-nonspecific alkaline phosphatase (TNAP) and their use to investigate whether the presence of AnxA5 impacts the kinetic parameters for hydrolysis of TNAP substrates at physiological pH.	1,2-Dipalmitoylphosphatidylcholine	46-50	annexin A5	Homo sapiens	204-209
26325078-4	2015	The presence of 10% DPPS in DPPC-liposomes causes a broadening of the transition peaks, with AnxA5 and TNAP promoting a decrease in DeltaH values.	1,2-Dipalmitoylphosphatidylcholine	28-32	annexin A5	Homo sapiens	93-98
26325078-5	2015	AnxA5 was able to mediate Ca(2+)-influx into the DPPC and DPPC:DPPS 10%-vesicles at physiological Ca(2+) concentrations (~2 mM).	1,2-Dipalmitoylphosphatidylcholine	49-53	annexin A5	Homo sapiens	0-5
26325078-5	2015	AnxA5 was able to mediate Ca(2+)-influx into the DPPC and DPPC:DPPS 10%-vesicles at physiological Ca(2+) concentrations (~2 mM).	1,2-Dipalmitoylphosphatidylcholine	58-62	annexin A5	Homo sapiens	0-5
25451198-1	2015	The dynamic properties of shaker-type Kv1.1 ion channel in its open, closed, & two mutated (E325D & V408A) states embedded in DPPC membrane have been investigated using all-atom force field-based MD simulation.	1,2-Dipalmitoylphosphatidylcholine	134-138	potassium voltage-gated channel subfamily A member 1	Homo sapiens	38-43
26154286-4	2015	METHODS: The film hydration method was used to prepare liposomal vasopressin consisting of: Dipalmitoylphosphatidylcholine, cholesterol, and dipalmitoyl phosphatidylethanolamine (20:20:1 mole ratio).	1,2-Dipalmitoylphosphatidylcholine	92-122	arginine vasopressin	Rattus norvegicus	65-76
25876023-4	2015	Bean-shaped structures characteristic of dipalmitoylphosphatidylcholine (DPPC) were converted to multilobed, fractal, or spiral domains as a result of exposure to ECNs, indicating that ECNs lower the line tension between domains in the case of zwitterionic lipids.	1,2-Dipalmitoylphosphatidylcholine	41-71	brain expressed associated with NEDD4 1	Homo sapiens	0-4
25876023-4	2015	Bean-shaped structures characteristic of dipalmitoylphosphatidylcholine (DPPC) were converted to multilobed, fractal, or spiral domains as a result of exposure to ECNs, indicating that ECNs lower the line tension between domains in the case of zwitterionic lipids.	1,2-Dipalmitoylphosphatidylcholine	73-77	brain expressed associated with NEDD4 1	Homo sapiens	0-4
26071844-4	2015	In our work, by comparing the mixed Cyt c-anionic (DPPS) and Cyt c-zwitterionic (DPPC/DPPE) monolayers, the adsorption capacity of Cyt c on lipid monolayers is DPPS>DPPE>DPPC, which is attributed to their different headgroup structures.	1,2-Dipalmitoylphosphatidylcholine	81-85	cytochrome c, somatic	Homo sapiens	61-66
26071844-4	2015	In our work, by comparing the mixed Cyt c-anionic (DPPS) and Cyt c-zwitterionic (DPPC/DPPE) monolayers, the adsorption capacity of Cyt c on lipid monolayers is DPPS>DPPE>DPPC, which is attributed to their different headgroup structures.	1,2-Dipalmitoylphosphatidylcholine	81-85	cytochrome c, somatic	Homo sapiens	61-66
26071844-4	2015	In our work, by comparing the mixed Cyt c-anionic (DPPS) and Cyt c-zwitterionic (DPPC/DPPE) monolayers, the adsorption capacity of Cyt c on lipid monolayers is DPPS>DPPE>DPPC, which is attributed to their different headgroup structures.	1,2-Dipalmitoylphosphatidylcholine	176-180	cytochrome c, somatic	Homo sapiens	61-66
26071844-4	2015	In our work, by comparing the mixed Cyt c-anionic (DPPS) and Cyt c-zwitterionic (DPPC/DPPE) monolayers, the adsorption capacity of Cyt c on lipid monolayers is DPPS>DPPE>DPPC, which is attributed to their different headgroup structures.	1,2-Dipalmitoylphosphatidylcholine	176-180	cytochrome c, somatic	Homo sapiens	61-66
26071844-7	2015	pi-T curve indicates that it takes more time for Cyt c molecular conformation to rearrange on DPPE monolayer than on DPPC.	1,2-Dipalmitoylphosphatidylcholine	117-121	cytochrome c, somatic	Homo sapiens	49-54
26250646-2	2015	In this work, we conducted coarse-grained simulation to investigate the interactions of binding units of chorela toxin (CTB) with mixed ganglioside GM1 and dipalmitoylphosphatidylcholine (DPPC) lipid bilayer membrane.	1,2-Dipalmitoylphosphatidylcholine	156-186	chitobiase	Homo sapiens	120-123
26250646-2	2015	In this work, we conducted coarse-grained simulation to investigate the interactions of binding units of chorela toxin (CTB) with mixed ganglioside GM1 and dipalmitoylphosphatidylcholine (DPPC) lipid bilayer membrane.	1,2-Dipalmitoylphosphatidylcholine	188-192	chitobiase	Homo sapiens	120-123
26001067-4	2015	Here, we have employed molecular modeling, docking and simulation techniques to examine the dynamical properties of Kv1.3 in both open and closed state conformation embedded in DPPC membrane as well as its modes of inhibition against the popularly known scorpion venom OSK1 and its three mutant analogues.	1,2-Dipalmitoylphosphatidylcholine	177-181	potassium voltage-gated channel subfamily A member 3	Homo sapiens	116-121
24853659-2	2015	An unusually high concentration of DPPC is a hallmark of PS and is critical to the formation of a high surface area, stable air/water interface; the unusual lipid polymorphisms observed in PS are dependent on surfactant proteins, particularly lung surfactant protein B (SP-B).	1,2-Dipalmitoylphosphatidylcholine	35-39	surfactant protein B	Homo sapiens	248-268
24853659-2	2015	An unusually high concentration of DPPC is a hallmark of PS and is critical to the formation of a high surface area, stable air/water interface; the unusual lipid polymorphisms observed in PS are dependent on surfactant proteins, particularly lung surfactant protein B (SP-B).	1,2-Dipalmitoylphosphatidylcholine	35-39	surfactant protein B	Homo sapiens	270-274
25112907-6	2014	This surfactant reduces the inhibitory effect of fibrinogen by selectively interacting with DPPC (dipalmitoylphosphatidylcholine) and mimicking some of the interfacial properties of the pulmonary surfactant protein B (SP-B).	1,2-Dipalmitoylphosphatidylcholine	92-96	fibrinogen beta chain	Homo sapiens	49-59
25617117-6	2015	Further, MD simulations of receptor and complex (13C-CCR8) inside dipalmitoylphosphatidylcholine lipid bilayers were performed to explore the effect of lipids.	1,2-Dipalmitoylphosphatidylcholine	66-96	C-C motif chemokine receptor 8	Homo sapiens	53-57
25223608-7	2014	Instead, one of the major and most important pulmonary surfactant phospholipids, dipalmitoylphosphatidylcholine (DPPC), bound to SPLUNC1 with high affinity and specificity.	1,2-Dipalmitoylphosphatidylcholine	81-111	BPI fold containing family A member 1	Homo sapiens	129-136
25223608-7	2014	Instead, one of the major and most important pulmonary surfactant phospholipids, dipalmitoylphosphatidylcholine (DPPC), bound to SPLUNC1 with high affinity and specificity.	1,2-Dipalmitoylphosphatidylcholine	113-117	BPI fold containing family A member 1	Homo sapiens	129-136
25441945-5	2014	In the present study, a homology model of the human FFAR1 was constructed and inserted into a pre-equilibrated DPPC/TIP3P membrane system.	1,2-Dipalmitoylphosphatidylcholine	111-115	free fatty acid receptor 1	Homo sapiens	52-57
25112907-6	2014	This surfactant reduces the inhibitory effect of fibrinogen by selectively interacting with DPPC (dipalmitoylphosphatidylcholine) and mimicking some of the interfacial properties of the pulmonary surfactant protein B (SP-B).	1,2-Dipalmitoylphosphatidylcholine	98-128	fibrinogen beta chain	Homo sapiens	49-59
25112907-8	2014	Hysteresis behaviors of the monolayers, which are composed of mixtures of DPPC and IPL at different molar ratios, indicate that with increasing amounts of IPL, the lipid losses from the interface induced by the presence of fibrinogen significantly decrease.	1,2-Dipalmitoylphosphatidylcholine	74-78	fibrinogen beta chain	Homo sapiens	223-233
24508605-3	2014	Molecular dynamic simulations (100 ns) were performed on the 3-D molecular model of beta3-AR and complexes of beta3-AR with potential agonists embedded in 2-dipalmitoyl-sn-phosphocholine (DPPC) bilayer-water system using OPLS (Optimized Potentials for Liquid Simulations) force field to gain structural insight into beta3-AR.	1,2-Dipalmitoylphosphatidylcholine	188-192	adrenoceptor beta 3	Homo sapiens	84-92
24618118-5	2014	In the present work, we studied the contribution of B-1 cells to the humoral response against ovalbumin (OVA) encapsulated into dipalmitoylphosphatidylcholine (DPPC) and cholesterol-containing liposomes.	1,2-Dipalmitoylphosphatidylcholine	128-158	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	94-103
24618118-5	2014	In the present work, we studied the contribution of B-1 cells to the humoral response against ovalbumin (OVA) encapsulated into dipalmitoylphosphatidylcholine (DPPC) and cholesterol-containing liposomes.	1,2-Dipalmitoylphosphatidylcholine	160-164	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	94-103
24508605-3	2014	Molecular dynamic simulations (100 ns) were performed on the 3-D molecular model of beta3-AR and complexes of beta3-AR with potential agonists embedded in 2-dipalmitoyl-sn-phosphocholine (DPPC) bilayer-water system using OPLS (Optimized Potentials for Liquid Simulations) force field to gain structural insight into beta3-AR.	1,2-Dipalmitoylphosphatidylcholine	188-192	adrenoceptor beta 3	Homo sapiens	110-118
24508605-3	2014	Molecular dynamic simulations (100 ns) were performed on the 3-D molecular model of beta3-AR and complexes of beta3-AR with potential agonists embedded in 2-dipalmitoyl-sn-phosphocholine (DPPC) bilayer-water system using OPLS (Optimized Potentials for Liquid Simulations) force field to gain structural insight into beta3-AR.	1,2-Dipalmitoylphosphatidylcholine	188-192	adrenoceptor beta 3	Homo sapiens	110-118
24806929-2	2014	The temperature dependence of the first moment of the (2)H spectrum of the sample made with DPPC-d62 and of the quadrupolar splittings of the chain-methyl-labeled DPPC-d6 sample are directly related to the temperature dependence of the critical order parameter eta, which scales as [Formula: see text] near the critical temperature.	1,2-Dipalmitoylphosphatidylcholine	92-96	endothelin receptor type A	Homo sapiens	261-264
24594322-8	2014	In addition, high IFN-gamma levels were detected in the culture supernatant of peritoneal cells from BALB/c and C57BL/6 mice immunized with Lp DPPC/OVA.	1,2-Dipalmitoylphosphatidylcholine	143-147	interferon gamma	Mus musculus	18-27
24297451-0	2014	Molecular dynamics simulation of human serum paraoxonase 1 in DPPC bilayer reveals a critical role of transmembrane helix H1 for HDL association.	1,2-Dipalmitoylphosphatidylcholine	62-66	paraoxonase 1	Homo sapiens	45-58
24441178-3	2014	To enhance the thermosensitive drug release, we incorporated elastin-like polypeptide (ELP), which is known to be a thermally responsive phase transition peptide into the dipalmitoylphosphatidylcholine (DPPC)-based liposome surface.	1,2-Dipalmitoylphosphatidylcholine	171-201	nuclear receptor subfamily 5 group A member 1	Homo sapiens	61-85
24441178-3	2014	To enhance the thermosensitive drug release, we incorporated elastin-like polypeptide (ELP), which is known to be a thermally responsive phase transition peptide into the dipalmitoylphosphatidylcholine (DPPC)-based liposome surface.	1,2-Dipalmitoylphosphatidylcholine	171-201	nuclear receptor subfamily 5 group A member 1	Homo sapiens	87-90
24441178-3	2014	To enhance the thermosensitive drug release, we incorporated elastin-like polypeptide (ELP), which is known to be a thermally responsive phase transition peptide into the dipalmitoylphosphatidylcholine (DPPC)-based liposome surface.	1,2-Dipalmitoylphosphatidylcholine	203-207	nuclear receptor subfamily 5 group A member 1	Homo sapiens	61-85
24441178-3	2014	To enhance the thermosensitive drug release, we incorporated elastin-like polypeptide (ELP), which is known to be a thermally responsive phase transition peptide into the dipalmitoylphosphatidylcholine (DPPC)-based liposome surface.	1,2-Dipalmitoylphosphatidylcholine	203-207	nuclear receptor subfamily 5 group A member 1	Homo sapiens	87-90
24359326-5	2014	Experiments with GUVs from a mixture of DPPC/BCP 2 confirm selective supramolecular recognition between the THY-functionalized NPs and the TRI-functionalized polymers, finally resulting in the selective removal of BCP 2 from the hybrid vesicle membrane as proven via facetation of the originally round and smooth vesicles.	1,2-Dipalmitoylphosphatidylcholine	40-44	opsin 1, short wave sensitive	Homo sapiens	214-217
24745688-9	2014	The successful DPPC model was obtained from MP2 calculations in an implicit polar environment (PCM).	1,2-Dipalmitoylphosphatidylcholine	15-19	tryptase pseudogene 1	Homo sapiens	44-47
24627953-1	2014	A method has been developed to encapsulate bovine serum albumin (BSA)-coated gold quantum clusters (AuQC@BSA) in a multilamellar system of dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	139-169	albumin	Homo sapiens	50-63
24627953-1	2014	A method has been developed to encapsulate bovine serum albumin (BSA)-coated gold quantum clusters (AuQC@BSA) in a multilamellar system of dipalmitoylphosphatidylcholine (DPPC).	1,2-Dipalmitoylphosphatidylcholine	171-175	albumin	Homo sapiens	50-63
24601791-5	2014	It was stated that the formation of domains with different content of FPh-prm/DPPC can be a reason for the membrane-related mechanism of chemoprevention associated with the inhibition of the outward transport of anticancer drugs by the glycoprotein P (Pgp) in cancer cells by the pyrimidine analog of FPh.	1,2-Dipalmitoylphosphatidylcholine	78-82	phosphoglycolate phosphatase	Homo sapiens	252-255
24471993-2	2014	In this work, the enzymes cellulase and alcohol dehydrogenase (ADH) were coimmobilized with dipalmitoylphosphatidylcholine (DPPC) as Langmuir-Blodgett (LB) films, and their biological activities were assayed by accommodating the structure formed in contact with cellulose.	1,2-Dipalmitoylphosphatidylcholine	92-122	aldo-keto reductase family 1 member A1	Homo sapiens	40-61
24471993-2	2014	In this work, the enzymes cellulase and alcohol dehydrogenase (ADH) were coimmobilized with dipalmitoylphosphatidylcholine (DPPC) as Langmuir-Blodgett (LB) films, and their biological activities were assayed by accommodating the structure formed in contact with cellulose.	1,2-Dipalmitoylphosphatidylcholine	92-122	aldo-keto reductase family 1 member A1	Homo sapiens	63-66
24471993-2	2014	In this work, the enzymes cellulase and alcohol dehydrogenase (ADH) were coimmobilized with dipalmitoylphosphatidylcholine (DPPC) as Langmuir-Blodgett (LB) films, and their biological activities were assayed by accommodating the structure formed in contact with cellulose.	1,2-Dipalmitoylphosphatidylcholine	124-128	aldo-keto reductase family 1 member A1	Homo sapiens	40-61
24471993-2	2014	In this work, the enzymes cellulase and alcohol dehydrogenase (ADH) were coimmobilized with dipalmitoylphosphatidylcholine (DPPC) as Langmuir-Blodgett (LB) films, and their biological activities were assayed by accommodating the structure formed in contact with cellulose.	1,2-Dipalmitoylphosphatidylcholine	124-128	aldo-keto reductase family 1 member A1	Homo sapiens	63-66
24297451-4	2014	Here, we studied the molecular association of full-length human PON1 (huPON1) with a HDL-mimetic dipalmitoylphosphatidylcholine (DPPC) bilayer using homology modeling and molecular dynamics simulations.	1,2-Dipalmitoylphosphatidylcholine	97-127	paraoxonase 1	Homo sapiens	64-68
24297451-4	2014	Here, we studied the molecular association of full-length human PON1 (huPON1) with a HDL-mimetic dipalmitoylphosphatidylcholine (DPPC) bilayer using homology modeling and molecular dynamics simulations.	1,2-Dipalmitoylphosphatidylcholine	129-133	paraoxonase 1	Homo sapiens	64-68
23416254-5	2013	The high surface activity of SEPT2 causes it to adsorb onto distinct types of lipid Langmuir monolayers, namely dipalmitoylphosphatidylcholine and PtdIns(4,5)P2.	1,2-Dipalmitoylphosphatidylcholine	112-142	septin 2	Homo sapiens	29-34
24339816-5	2013	Non-selective beta1-blockers, but not selective ones, intensively acted on 1,2-dipalmitoylphosphatidylcholine (DPPC) liposomal membranes and cardiomyocyte-mimetic membranes to increase the membrane fluidity.	1,2-Dipalmitoylphosphatidylcholine	75-109	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	14-19
24339816-5	2013	Non-selective beta1-blockers, but not selective ones, intensively acted on 1,2-dipalmitoylphosphatidylcholine (DPPC) liposomal membranes and cardiomyocyte-mimetic membranes to increase the membrane fluidity.	1,2-Dipalmitoylphosphatidylcholine	111-115	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	14-19
23947814-6	2013	Like hLA binding, OA binding increases the affinity of bLG for small unilamellar dipalmitoylphosphatidylcholine vesicles, while pPA efficiently binds to the vesicles irrespective of OA binding.	1,2-Dipalmitoylphosphatidylcholine	81-111	beta-lactoglobulin	Bos taurus	55-58
23930911-8	2013	In presence of sodium deoxycholate (NaDC) and sodium cholate (NaC) in DPPC vesicles, ANS experiences restriction in rotational mobility which is evident from the variation in steady-state fluorescence anisotropy and fluorescence anisotropy decay parameters.	1,2-Dipalmitoylphosphatidylcholine	70-74	synuclein alpha	Homo sapiens	62-65
23727005-8	2013	Specifically, the rate of PLA2 hydrolysis of the coumarin labeled phosphatidylcholine analogs was less than three times slower than the natural substrate dipalmitoyl phosphatidylcholine (DPPC) under the same experimental conditions.	1,2-Dipalmitoylphosphatidylcholine	154-185	phospholipase A2 group IB	Homo sapiens	26-30
23727005-8	2013	Specifically, the rate of PLA2 hydrolysis of the coumarin labeled phosphatidylcholine analogs was less than three times slower than the natural substrate dipalmitoyl phosphatidylcholine (DPPC) under the same experimental conditions.	1,2-Dipalmitoylphosphatidylcholine	187-191	phospholipase A2 group IB	Homo sapiens	26-30
23416254-7	2013	Most importantly, in situ polarization-modulated infrared reflection absorption spectroscopy results indicated that the native secondary structure of SEPT2 is preserved upon interacting with PtdIns(4,5)P2, but not when dipalmitoylphosphatidylcholine is at the air/water interface.	1,2-Dipalmitoylphosphatidylcholine	219-249	septin 2	Homo sapiens	150-155
23815761-0	2014	Molecular dynamics simulation of neuropeptide B and neuropeptide W in the dipalmitoylphosphatidylcholine membrane bilayer.	1,2-Dipalmitoylphosphatidylcholine	74-104	neuropeptide B	Homo sapiens	33-47
23815761-0	2014	Molecular dynamics simulation of neuropeptide B and neuropeptide W in the dipalmitoylphosphatidylcholine membrane bilayer.	1,2-Dipalmitoylphosphatidylcholine	74-104	neuropeptide W	Homo sapiens	52-66
23815761-4	2014	Herein, we investigated the structure, orientation, and interaction of NPB and NPW in a dipalmitoylphosphatidylcholine bilayer using long-range molecular dynamics (MD) simulation.	1,2-Dipalmitoylphosphatidylcholine	88-118	neuropeptide B	Homo sapiens	71-74
24156610-3	2013	The beta-sheet structure adopted by A6R is disrupted in the presence of DPPC.	1,2-Dipalmitoylphosphatidylcholine	72-76	twinfilin actin binding protein 2	Homo sapiens	36-39
24156610-4	2013	A strong effect on the small-angle X-ray scattering profile is observed: the Bragg peaks from the DPPC bilayers in the vesicle walls are eliminated in the presence of A6R and only bilayer form factor peaks are observed.	1,2-Dipalmitoylphosphatidylcholine	98-102	twinfilin actin binding protein 2	Homo sapiens	167-170
24156610-5	2013	All of these observations point to the interaction of A6R with DPPC bilayers.	1,2-Dipalmitoylphosphatidylcholine	63-67	twinfilin actin binding protein 2	Homo sapiens	54-57
24127854-5	2013	In addition, the introduction of SPC instead of the traditionally used phospholipids (such as dioleoyl phosphatidylethanolamine (DOPE) or dipalmitoyl phosphatidylcholine (DPPC)) results in a much lower cost and a better serum stability.	1,2-Dipalmitoylphosphatidylcholine	138-169	proline rich protein gene cluster	Homo sapiens	33-36
23360953-6	2013	We found that Ca(2+) is the main factor which regulates the interaction of AnxA6 with monolayers composed of neutral lipids, such as DPPC and sphingomyelin, and may also determine AnxA6 localization in cholesterol and sphingomyelin enriched microdomains, thus contributing to the etiology of the NPC disease.	1,2-Dipalmitoylphosphatidylcholine	133-137	annexin A6	Homo sapiens	75-80
23805757-3	2013	The segregation of DPPC-enriched ordered phase has been related with the ability of surfactant films to produce very low tensions, while the presence in surfactant of two specific hydrophobic polypeptides, SP-B and SP-C, is absolutely required to facilitate surfactant dynamics, including film formation and re-spreading during expansion at inspiration.	1,2-Dipalmitoylphosphatidylcholine	19-23	surfactant protein B	Homo sapiens	206-210
22995243-3	2013	AFM observations for the l/l bilayer show that the hydrolysis rate for l-DPPC is significantly increased by PLA(2) and most of the hydrolysis products desorb from substrate surface in 40 min.	1,2-Dipalmitoylphosphatidylcholine	71-77	phospholipase A2 group IIA	Homo sapiens	108-113
23805757-3	2013	The segregation of DPPC-enriched ordered phase has been related with the ability of surfactant films to produce very low tensions, while the presence in surfactant of two specific hydrophobic polypeptides, SP-B and SP-C, is absolutely required to facilitate surfactant dynamics, including film formation and re-spreading during expansion at inspiration.	1,2-Dipalmitoylphosphatidylcholine	19-23	surfactant protein C	Homo sapiens	215-219
22403024-6	2012	SOD had a strong interaction with DPPC liposomes containing high concentration of cholesterol.	1,2-Dipalmitoylphosphatidylcholine	34-38	superoxide dismutase 1	Homo sapiens	0-3
22975396-3	2012	The interaction of glucose, insulin, and a mixture of glucose and insulin to the DPPC monolayer were investigated via surface pressure-area per molecule Langmuir isotherms and fluorescence microscopy.	1,2-Dipalmitoylphosphatidylcholine	81-85	insulin	Homo sapiens	28-35
22975396-3	2012	The interaction of glucose, insulin, and a mixture of glucose and insulin to the DPPC monolayer were investigated via surface pressure-area per molecule Langmuir isotherms and fluorescence microscopy.	1,2-Dipalmitoylphosphatidylcholine	81-85	insulin	Homo sapiens	66-73
22975396-5	2012	The presence of a mixture of insulin and glucose affected the molecular packing in the DPPC monolayer differently than the pure insulin or glucose solutions, and the glucose-insulin mixture was seen to be able to penetrate through the monolayer.	1,2-Dipalmitoylphosphatidylcholine	87-91	insulin	Homo sapiens	29-36
22772075-2	2012	Both surface pressure and surface potential isotherms became more expanded upon addition of TRP3 (DPPE~DPPC<<DPPA<DPPG).	1,2-Dipalmitoylphosphatidylcholine	103-107	tRNA-Pro (anticodon TGG) 3-1	Homo sapiens	92-96
22759980-8	2012	PEG-TSL and PEG/Lyso-TSL were more susceptible to DPPC/Chol-LLV than DPPG(2)-containing TSL.	1,2-Dipalmitoylphosphatidylcholine	50-54	progestagen associated endometrial protein	Homo sapiens	0-3
22759980-8	2012	PEG-TSL and PEG/Lyso-TSL were more susceptible to DPPC/Chol-LLV than DPPG(2)-containing TSL.	1,2-Dipalmitoylphosphatidylcholine	50-54	progestagen associated endometrial protein	Homo sapiens	12-15
22773689-5	2012	Activities of bee venom PLA(2) on dipalmitoylphosphatidylcholine (DPPC) and dioleylphosphatidylcholine (DOPC) bilayers were measured.	1,2-Dipalmitoylphosphatidylcholine	34-64	phospholipase A2 group IB	Rattus norvegicus	24-30
22773689-5	2012	Activities of bee venom PLA(2) on dipalmitoylphosphatidylcholine (DPPC) and dioleylphosphatidylcholine (DOPC) bilayers were measured.	1,2-Dipalmitoylphosphatidylcholine	66-70	phospholipase A2 group IB	Rattus norvegicus	24-30
22487055-10	2012	HA adjuvanted with the DC-Chol/DPPC (50:50) liposomes elicited significantly higher total IgG1 and IgG2a titers compared to the other liposomal HA formulations and non-adjuvanted HA.	1,2-Dipalmitoylphosphatidylcholine	31-35	LOC105243590	Mus musculus	90-94
22487055-10	2012	HA adjuvanted with the DC-Chol/DPPC (50:50) liposomes elicited significantly higher total IgG1 and IgG2a titers compared to the other liposomal HA formulations and non-adjuvanted HA.	1,2-Dipalmitoylphosphatidylcholine	31-35	immunoglobulin heavy variable V1-9	Mus musculus	99-104
22154096-0	2012	Monolayer and Brewster angle microscopy study of human serum albumin-dipalmitoyl phosphatidyl choline mixtures at the air-water interface.	1,2-Dipalmitoylphosphatidylcholine	69-101	albumin	Homo sapiens	55-68