PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 17889379-6 2007 Furthermore, the observations of (i) the expression of the ABC multidrug proteins in detoxifying tissues; (ii) the induction of these transporters upon exposure to an environmental organic pollutant tributyltin (TBT); and (iii) the concentration-dependent inhibition of rhodamine efflux by TBT imply a possible role of these proteins in the export of TBT. Rhodamines 270-279 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 59-62 17939673-0 2007 Multisignaling optical-electrochemical sensor for Hg2+ based on a rhodamine derivative with a ferrocene unit. Rhodamines 66-75 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 50-53 17912240-7 2007 In addition, ZD6474 increases the intracellular accumulation of the P-gp substrate, rhodamine-123, and ADR, by enhancing the uptake and/or decreasing the efflux of these compounds in resistant cells. Rhodamines 84-93 ATP binding cassette subfamily B member 1 Homo sapiens 68-72 17916018-5 2007 RESULTS: Known P-gp substrate drugs ivermectin and cyclosporin A altered rhodamine efflux by 90% and 95%, respectively. Rhodamines 73-82 PGP Canis lupus familiaris 15-19 17917278-9 2007 At doses of 100 and 200 microM, Cap inhibited the transport of rhodamine 123 by P-gp-mediated efflux in Caco-2 cells. Rhodamines 63-72 ATP binding cassette subfamily B member 1 Homo sapiens 80-84 17333245-3 2007 CDCA and deoxycholic acid pre-treatment for 24-96 h (100 microM) also increased Pgp activity measured as rhodamine efflux, while cholic acid and taurocholic acid were not effective in concentrations up to 600 microM. Rhodamines 105-114 PGP Canis lupus familiaris 80-83 17385225-3 2007 By substituting the normal bFGF with rhodamine-labeled one (Rd-bFGF), a linear increase of the absorbance versus bilayer number was recorded. Rhodamines 37-46 fibroblast growth factor 2 Homo sapiens 27-31 17385225-3 2007 By substituting the normal bFGF with rhodamine-labeled one (Rd-bFGF), a linear increase of the absorbance versus bilayer number was recorded. Rhodamines 37-46 fibroblast growth factor 2 Homo sapiens 63-67 17646160-8 2007 This peptide also inhibited the resonance energy transfer between membrane-bound fluorescein-labeled fVa (donor) and rhodamine-active site-labeled S360C-APC (acceptor). Rhodamines 117-126 APC regulator of WNT signaling pathway Homo sapiens 153-156 17705442-13 2007 Inhibition of P-gp-mediated rhodamine efflux with AOT-alginate nanoparticles was confirmed in primary brain microvessel endothelial cells. Rhodamines 28-37 ATP binding cassette subfamily B member 1 Homo sapiens 14-18 17652134-4 2007 Using the unmodified transcript of Escherichia coli tRNAPro as an example, which has U17 and U17a in the D loop, we show that Dus1p catalyzes conversion of one of these Us (mostly U17a) to D, and that the modified tRNA can be labeled with the fluorophores proflavin and rhodamine 110, with overall labeling yields comparable to those obtained with the native yeast tRNAPhe. Rhodamines 270-279 tRNA dihydrouridine synthase Saccharomyces cerevisiae S288C 126-131 17893673-6 2007 Punctate Ca(v)1.3 labeling was evident throughout the IPL and around the cell bodies in the outer nuclear (ONL), inner nuclear (INL) and on somas and axons of ganglion cells labeled with rhodamine-conjugated dextran. Rhodamines 187-196 immunoglobulin lambda variable 2-11 Homo sapiens 9-17 17701591-3 2007 Ex vivo treatment of CLL cells with HF markedly impaired the activity of P-gp, as measured by the inhibition of the capacity of the treated cells to efflux the rhodamine 123 probe. Rhodamines 160-169 phosphoglycolate phosphatase Homo sapiens 73-77 17591912-5 2007 Rhodamine (Rh)-labeled bFGF-NPs were injected intravitreally and visualized by confocal microscopy to determine the localization of the nanoparticles in the retina. Rhodamines 0-9 fibroblast growth factor 2 Homo sapiens 23-27 17591912-5 2007 Rhodamine (Rh)-labeled bFGF-NPs were injected intravitreally and visualized by confocal microscopy to determine the localization of the nanoparticles in the retina. Rhodamines 0-2 fibroblast growth factor 2 Homo sapiens 23-27 17496218-7 2007 At the medullary sites, a specific and high-intensity binding for rhodamine-ANG-(1-7) was also shown. Rhodamines 66-75 angiogenin Rattus norvegicus 76-84 17635801-2 2007 In this study, the activities of two members of the superfamily of ATP-binding cassette (ABC) transport proteins, ABCB1 and ABCC (measured by rhodamine 123 efflux and Fluo-3 efflux respectively), were compared in murine bone marrow cells and thymocytes of young (3-4 weeks old), adult (2-3 months old) and old (18 months old) mice. Rhodamines 142-151 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 114-119 17635801-2 2007 In this study, the activities of two members of the superfamily of ATP-binding cassette (ABC) transport proteins, ABCB1 and ABCC (measured by rhodamine 123 efflux and Fluo-3 efflux respectively), were compared in murine bone marrow cells and thymocytes of young (3-4 weeks old), adult (2-3 months old) and old (18 months old) mice. Rhodamines 142-151 ATP-binding cassette, sub-family A (ABC1), member 3 Mus musculus 124-128 17530763-0 2007 Highly sensitive and selective chemosensor for Hg2+ based on the rhodamine fluorophore. Rhodamines 65-74 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 47-50 17530811-3 2007 The (PAA-Az/PAA-Alk)-coated particles were subsequently functionalized by exploiting the free alkyne click moieties present in the film upon exposure to an azide-modified rhodamine dye. Rhodamines 171-180 ALK receptor tyrosine kinase Homo sapiens 16-19 17337527-6 2007 By monitoring transiently expressed green fluorescent protein fused to the actin-binding domain of mouse talin, we observed the concentration of actin bundles at the cross-pollen attachment site and actin reorganization and likely depolymerization at the self-pollen attachment site; the results correspond to those obtained by rhodamine-phalloidin staining. Rhodamines 328-337 LOW QUALITY PROTEIN: actin Brassica rapa 75-80 17202226-6 2007 In live cells, transiently expressed SGK1-AFP clearly colocalized with the mitochondrial marker rhodamine 123. Rhodamines 96-105 serine/threonine-protein kinase Sgk1 Oryctolagus cuniculus 37-41 17229686-7 2007 Quantification of filamentous actin (F-actin) content by using rhodamine-conjugated phalloidin and flow cytometry showed an elevated F-actin content in NSP4-EGFP-expressing and rotavirus-infected cells in comparison with that in nonexpressing and noninfected cells. Rhodamines 63-72 serine protease 57 Homo sapiens 152-156 17398282-5 2007 FCS measurement of the fluorophore rhodamine-labeled Abeta (Rh-Abeta) shows diffusion times: 0.1 ms, 1.1 ms and 5.9 ms. Rhodamines 35-44 amyloid beta precursor protein Homo sapiens 53-58 17398282-5 2007 FCS measurement of the fluorophore rhodamine-labeled Abeta (Rh-Abeta) shows diffusion times: 0.1 ms, 1.1 ms and 5.9 ms. Rhodamines 35-44 amyloid beta precursor protein Homo sapiens 63-68 17414424-5 2007 Histaminase counteracted free radical-mediated tissue injury, as judged by a significant decrease in the plasma and tissue levels of peroxidation and nitration products (oxidized rhodamine, malondialdehyde, nitrotyrosine), DNA damage markers (8-hydroxy-2"-deoxyguanosine, poly-adenosine diphosphate-ribosylated DNA) and consumption of tissue antioxidant enzymes (superoxide dismutase). Rhodamines 179-188 amine oxidase, copper containing 1 Rattus norvegicus 0-11 17982279-6 2007 RESULTS: Addition of cobalamin to the cells led to an increase in MS activity, to a significant decrease in mdr-1 gene expression which is correlated to an increase in retention of the Pgp substrate Rhodamine 123. Rhodamines 199-208 ATP binding cassette subfamily B member 1 Homo sapiens 185-188 17286965-5 2007 Furthermore, C-4 treatment significantly increases in intracellular accumulation of fluorescent P-gp substrate rhodamine 123, indicating that C-4 treatment leads to reversal of the MDR phenotype resulting from an increased accumulation of anticancer drugs by inhibiting drug efflux function of P-gp. Rhodamines 111-120 ATP binding cassette subfamily B member 1 Homo sapiens 96-100 17266731-7 2007 The drug-sensitizing effect of overexpressed loss-of-function pdr3 mutant alleles correlated with their ability to suppress PDR5 transcription and rhodamine 6G accumulation in transformants of the wild-type and Deltapdr1 mutant strains. Rhodamines 147-156 drug-responsive transcription factor PDR3 Saccharomyces cerevisiae S288C 62-66 16990597-2 2007 We report that the rhodamine 123 (Rho 123) dye effluxing fraction of the Lin-CD34+CD38- population contains SCID-repopulating cells (SRCs) capable of long-term repopulation in primary nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice. Rhodamines 19-28 CD34 antigen Mus musculus 77-81 16990597-2 2007 We report that the rhodamine 123 (Rho 123) dye effluxing fraction of the Lin-CD34+CD38- population contains SCID-repopulating cells (SRCs) capable of long-term repopulation in primary nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice. Rhodamines 19-28 CD38 antigen Mus musculus 82-86 17727795-0 2007 Lipid excipients Peceol and Gelucire 44/14 decrease P-glycoprotein mediated efflux of rhodamine 123 partially due to modifying P-glycoprotein protein expression within Caco-2 cells. Rhodamines 86-95 ATP binding cassette subfamily B member 1 Homo sapiens 52-66 17727795-0 2007 Lipid excipients Peceol and Gelucire 44/14 decrease P-glycoprotein mediated efflux of rhodamine 123 partially due to modifying P-glycoprotein protein expression within Caco-2 cells. Rhodamines 86-95 ATP binding cassette subfamily B member 1 Homo sapiens 127-141 17078922-5 2006 Further, the rhodamine labeled Epap-1 specifically bound to gp120 expressed on the surface of HL2/3 cells during fusion reaction thereby inhibiting viral entry. Rhodamines 13-22 inter-alpha-trypsin inhibitor heavy chain 4 Homo sapiens 60-65 17078922-5 2006 Further, the rhodamine labeled Epap-1 specifically bound to gp120 expressed on the surface of HL2/3 cells during fusion reaction thereby inhibiting viral entry. Rhodamines 13-22 intelectin 2 Homo sapiens 94-97 17054045-9 2006 P. amarus derivatives were also found to be effective in inhibiting Pgp activity as assessed by rhodamine accumulation in Lucena-1 cells, as were the classical Pgp inhibitors, cyclosporine A (160 nM), PSC-833 (2 microM) and verapamil (5 microM). Rhodamines 96-105 phosphoglycolate phosphatase Homo sapiens 68-71 16996216-3 2006 Expression of ABCB1 mRNA and ABCB1 activity were examined in atorvastatin-treated and control cells and PBMCs using real-time PCR and Rhodamine 123 efflux assay. Rhodamines 134-143 ATP binding cassette subfamily B member 1 Homo sapiens 14-19 17130520-5 2006 Concurrently, SGLT1 rhodamine fluorescence intensity increased with depolarizing and decreased with hyperpolarizing voltages (DeltaF). Rhodamines 20-29 solute carrier family 5 member 1 Homo sapiens 14-19 16910657-6 2006 Confocal images proved that some ACBP-1 localized into the nucleus (as expected) and, most significantly, it could be visualized more effectively by irradiating at the donor (fluorescein-like) part of the cassette, than the acceptor (rhodamine-like) part. Rhodamines 234-243 carboxypeptidase N subunit 2 Homo sapiens 33-37 16782851-5 2006 Rhodamine-related fluorescence could be suppressed by preincubation with a specific inhibitor of TPP-I. Rhodamines 0-9 tripeptidyl peptidase 1 Homo sapiens 97-102 16554405-8 2006 This work reveals the usefulness of rhodamine-based Ca2+ indicators in examining the role of intramitochondrial Ca2+ in mitochondrial (patho) physiology. Rhodamines 36-45 carbonic anhydrase 2 Homo sapiens 52-55 16554405-8 2006 This work reveals the usefulness of rhodamine-based Ca2+ indicators in examining the role of intramitochondrial Ca2+ in mitochondrial (patho) physiology. Rhodamines 36-45 carbonic anhydrase 2 Homo sapiens 112-115 16530756-11 2006 Rhodamine uptake after treatment with verapamil was significantly greater in D407 and MDCK-MDR1, indicating functional expression of P-gp in these two cell lines. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 86-95 16926504-1 2006 Specific interaction between green fluorescent protein (GFP)-tagged human alpha- or gamma-enolase(97-242) (alpha or gammaENO(97-242)) and the rhodamine-labeled DNA fragment containing the c-myc P2 promoter was detected by a fluorescence resonance energy transfer (FRET)-based assay, designated as a "real-time FRET assay." Rhodamines 142-151 enolase 1 Homo sapiens 74-97 16889411-4 2006 To meet this objective, we report the synthesis and characterization of two rhodamine-conjugated probes that covalently label the active site of the PTPs in an activity-dependent manner, thus providing a direct readout of PTP activity and superior sensitivity, robustness, and quantifiability to previously reported biotinylated probes. Rhodamines 76-85 6-pyruvoyltetrahydropterin synthase Homo sapiens 149-153 16889411-4 2006 To meet this objective, we report the synthesis and characterization of two rhodamine-conjugated probes that covalently label the active site of the PTPs in an activity-dependent manner, thus providing a direct readout of PTP activity and superior sensitivity, robustness, and quantifiability to previously reported biotinylated probes. Rhodamines 76-85 protein tyrosine phosphatase receptor type U Homo sapiens 149-152 16530756-11 2006 Rhodamine uptake after treatment with verapamil was significantly greater in D407 and MDCK-MDR1, indicating functional expression of P-gp in these two cell lines. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 133-137 16601691-2 2006 The myosin V was labeled with bifunctional rhodamine on one of its calmodulin light chains. Rhodamines 43-52 myosin VA Gallus gallus 4-12 16129693-7 2005 Fluorescence and capacitance measurements evidenced a fast translocation of rhodamine-coupled S100A1 from the extracellular space into cardiomyocytes. Rhodamines 76-85 S100 calcium binding protein A1 Rattus norvegicus 94-100 16614073-4 2006 We have measured the 3D orientation and stepping behavior of single bifunctional rhodamine probes attached to one of the calmodulins of the light-chain domain (LCD) of myosin V as myosin V moves along actin. Rhodamines 81-90 myosin VA Homo sapiens 168-176 16614073-4 2006 We have measured the 3D orientation and stepping behavior of single bifunctional rhodamine probes attached to one of the calmodulins of the light-chain domain (LCD) of myosin V as myosin V moves along actin. Rhodamines 81-90 myosin VA Homo sapiens 180-188 16491453-2 2006 Among the active lathyrane derivatives 1 - 3, compound 2 displayed the highest inhibition of rhodamine 123 efflux of human MDR1 gene transfected mouse lymphoma cells when compared to the untreated cells or the positive control verapamil. Rhodamines 93-102 ATP binding cassette subfamily B member 1 Homo sapiens 123-127 16319528-6 2006 Compared KBv200/MDR1sh cells with KBv200 cells, resistance to vincristine and doxorubicin decreased from 62.4-fold to 10.5-fold and from 74.5-fold to 9.5-fold respectively, and intracellular doxorubicin accumulation enhanced from 0.30 +/- 0.08 nmoles/10(6) cells to 0.86 +/- 0.16 nmoles/10(6) cells, and the fluorescence intensity of intracellular Rhodamine 123 accumulation increased from 3.58 +/- 1.63/10(6) cells to 13.96 +/- 3.07/10(6) cells. Rhodamines 348-357 ATP binding cassette subfamily B member 1 Homo sapiens 16-20 16380642-12 2006 Association-dissociation of the myosin head was probed with rhodamine attached at cys707 of the heavy chain of myosin. Rhodamines 60-69 myosin heavy chain 14 Homo sapiens 32-38 16380642-12 2006 Association-dissociation of the myosin head was probed with rhodamine attached at cys707 of the heavy chain of myosin. Rhodamines 60-69 myosin heavy chain 14 Homo sapiens 111-117 16433037-3 2006 Seven benzo[a]phenoxazines were observed to increase the amount of rhodamine 123 accumulated by resistant cells, i.e. to be new effective MDR modulators. Rhodamines 67-76 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 138-141 16234340-4 2005 The calcium mobilization resulting from ionomycin treatment of nNOS-expressing 293T cells induced a robust increase in emission intensity, as measured using a standard rhodamine filter set. Rhodamines 168-177 nitric oxide synthase 1 Homo sapiens 63-67 16302792-0 2005 Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter. Rhodamines 0-9 solute carrier family 6 member 3 Homo sapiens 125-145 16302792-3 2005 The resulting 2-substituted (5) and N-substituted (9) rhodamine-labeled ligands provided the highest DAT binding affinities expressed in COS-7 cells (Ki= 27 and 18 nM, respectively) in the series. Rhodamines 54-63 solute carrier family 6 member 3 Homo sapiens 101-104 16124934-7 2005 P-gp function was evaluated by the difference between rhodamine 123 transport with and without verapamil. Rhodamines 54-63 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 0-4 16229491-5 2005 By carrying out single and sequential dual fluorescence titrations of purified P-glycoprotein with the two substrates, we observed that bound LDS-751 interacted with bound rhodamine 123. Rhodamines 172-181 ATP binding cassette subfamily B member 1 Homo sapiens 79-93 16150484-3 2005 In the present study, the expression of PAR2 and tachykinins were investigated in rat trigeminal neurons that were identified by retrograde labeling with rhodamine dye from the nasal mucosa by using neuronal tracing in combination with immunohistochemistry. Rhodamines 154-163 F2R like trypsin receptor 1 Rattus norvegicus 40-44 16150484-7 2005 Of the rhodamine-labeled trigeminal neurons, 52.5+/-1.8% were immunoreactive for only PAR2 expression, 7.3+/-1.9% contained tachykinins and PAR2, and 3.1+/-0.4 of the rhodamine-labeled trigeminal neurons were non-immunoreactive PAR2, but were positive for tachykinins-immunoreactivity. Rhodamines 7-16 F2R like trypsin receptor 1 Rattus norvegicus 86-90 16150484-7 2005 Of the rhodamine-labeled trigeminal neurons, 52.5+/-1.8% were immunoreactive for only PAR2 expression, 7.3+/-1.9% contained tachykinins and PAR2, and 3.1+/-0.4 of the rhodamine-labeled trigeminal neurons were non-immunoreactive PAR2, but were positive for tachykinins-immunoreactivity. Rhodamines 7-16 F2R like trypsin receptor 1 Rattus norvegicus 140-144 16150484-7 2005 Of the rhodamine-labeled trigeminal neurons, 52.5+/-1.8% were immunoreactive for only PAR2 expression, 7.3+/-1.9% contained tachykinins and PAR2, and 3.1+/-0.4 of the rhodamine-labeled trigeminal neurons were non-immunoreactive PAR2, but were positive for tachykinins-immunoreactivity. Rhodamines 7-16 F2R like trypsin receptor 1 Rattus norvegicus 140-144 16103191-7 2005 Intracellular accumulation of sNS1 in Huh7 cells enhanced the fluid phase uptake of rhodamine-labeled dextran. Rhodamines 84-93 MIR7-3 host gene Homo sapiens 38-42 15856282-3 2005 We demonstrated by using rhodamine-phalloidin staining, the localization of actin filaments on the mitotic spindles of tobacco BY-2 cells when the cells were treated with cytochalasin D. Rhodamines 25-34 actin Nicotiana tabacum 76-81 15963852-5 2005 Cellular efflux of the PgP substates rhodamine and doxorubicin was abolished. Rhodamines 37-46 ATP binding cassette subfamily B member 1 Homo sapiens 23-26 15968171-6 2005 Quantitative immunohistochemistry with rhodamine-conjugated anti-OGFr antibodies revealed twofold more OGFr expression in the central and peripheral epithelium of transfected corneas relative to naive corneas. Rhodamines 39-48 opioid growth factor receptor Rattus norvegicus 65-69 15968171-6 2005 Quantitative immunohistochemistry with rhodamine-conjugated anti-OGFr antibodies revealed twofold more OGFr expression in the central and peripheral epithelium of transfected corneas relative to naive corneas. Rhodamines 39-48 opioid growth factor receptor Rattus norvegicus 103-107 15796199-3 2005 The rhodamine 123 accumulation of the P-glycoprotein (P-gp)-expressing cells increased up to 46.4, while 2,7"-bis(2-carboxyethyl)-5(6)-carboxy-fluorescein acetoxymethyl ester (BCECF-AM) accumulation of the MRP-expressing cells increased up to 1.6, in fluorescence activity ratio (FAR). Rhodamines 4-13 ATP binding cassette subfamily B member 1 Homo sapiens 38-52 16241060-0 2005 [Determination of vitamin B12 concentration by fluorescence quenching with acridine orange-rhodamine 6G energy transfer system]. Rhodamines 91-100 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 26-29 15885661-3 2005 In IL10(-/-) enterocolitis mice, rhodamine 123 efflux was reduced by two to three-fold along the small and large intestine. Rhodamines 33-42 interleukin 10 Mus musculus 3-7 15934943-8 2005 Tat(1-72)-mediated changes in P-gp expression were correlated with increased rhodamine 123 efflux, indicating the up-regulation of transporter functions of P-gp. Rhodamines 77-86 tyrosine aminotransferase Mus musculus 0-3 15934943-8 2005 Tat(1-72)-mediated changes in P-gp expression were correlated with increased rhodamine 123 efflux, indicating the up-regulation of transporter functions of P-gp. Rhodamines 77-86 phosphoglycolate phosphatase Mus musculus 30-34 15934943-8 2005 Tat(1-72)-mediated changes in P-gp expression were correlated with increased rhodamine 123 efflux, indicating the up-regulation of transporter functions of P-gp. Rhodamines 77-86 phosphoglycolate phosphatase Mus musculus 156-160 15807535-8 2005 The ABCG2 (N596Q) variant is also functional, demonstrating rhodamine 123 transport in intact cells comparable to that in cells expressing glycosylated ABCG2. Rhodamines 60-69 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 4-9 15796199-3 2005 The rhodamine 123 accumulation of the P-glycoprotein (P-gp)-expressing cells increased up to 46.4, while 2,7"-bis(2-carboxyethyl)-5(6)-carboxy-fluorescein acetoxymethyl ester (BCECF-AM) accumulation of the MRP-expressing cells increased up to 1.6, in fluorescence activity ratio (FAR). Rhodamines 4-13 ATP binding cassette subfamily B member 1 Homo sapiens 54-58 15796199-3 2005 The rhodamine 123 accumulation of the P-glycoprotein (P-gp)-expressing cells increased up to 46.4, while 2,7"-bis(2-carboxyethyl)-5(6)-carboxy-fluorescein acetoxymethyl ester (BCECF-AM) accumulation of the MRP-expressing cells increased up to 1.6, in fluorescence activity ratio (FAR). Rhodamines 4-13 ATP binding cassette subfamily C member 1 Homo sapiens 206-209 15663893-3 2005 The amount of intracellular rhodamine (Rh123) was determined, using a fluorescence spectrophotometer, to evaluate the function of P-gp. Rhodamines 28-37 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 130-134 15490242-9 2004 Supernatant and cells collected after circulation over normal mucin showed increased rhodamine fluorescence, indicative of oxidative burst. Rhodamines 85-94 LOC100508689 Homo sapiens 62-67 15661399-6 2005 P-gp interaction with GC was assessed by modulation of rhodamine accumulation. Rhodamines 55-64 phosphoglycolate phosphatase Homo sapiens 0-4 15331656-7 2005 Furthermore, it potently blocked P-glycoprotein-mediated rhodamine 123 efflux under serum-free conditions (EC(50), approximately 8 microM), however, with reduced activity at increased serum concentrations (EC(50) at 10% serum, approximately 35 microM). Rhodamines 57-66 ATP binding cassette subfamily B member 1 Homo sapiens 33-47 15486081-9 2004 FL3 cells grown on GlcNAc effluxed 5.3 times as much Cdr1p substrate rhodamine 6G, over a 10 min period, as FL3 cells grown on glucose, and this rhodamine 6G efflux was inhibited by including fluconazole in the assay. Rhodamines 69-78 cerebellar degeneration related protein 1 Homo sapiens 53-58 15486081-9 2004 FL3 cells grown on GlcNAc effluxed 5.3 times as much Cdr1p substrate rhodamine 6G, over a 10 min period, as FL3 cells grown on glucose, and this rhodamine 6G efflux was inhibited by including fluconazole in the assay. Rhodamines 145-154 cerebellar degeneration related protein 1 Homo sapiens 53-58 15458769-9 2004 Moreover, it was found that both celecoxib and diclofenac have the potential to inhibit the function of P-glycoprotein (P-gp) in ECC using rhodamine uptake and efflux assays. Rhodamines 139-148 phosphoglycolate phosphatase Mus musculus 104-118 15547738-5 2004 MDR1 functional activity was performed by a rhodamine (Rhd)-123 efflux test with or without verapamil. Rhodamines 44-53 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 15547738-5 2004 MDR1 functional activity was performed by a rhodamine (Rhd)-123 efflux test with or without verapamil. Rhodamines 55-58 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 15458769-9 2004 Moreover, it was found that both celecoxib and diclofenac have the potential to inhibit the function of P-glycoprotein (P-gp) in ECC using rhodamine uptake and efflux assays. Rhodamines 139-148 phosphoglycolate phosphatase Mus musculus 120-124 15326087-6 2004 Furthermore, AVE displaced the binding of 125I-Ang-(1-7) in Mas-transfected monkey kidney cells (COS) cells (IC50=4.75x10(-8) mol/L) and of rhodamine-Ang-(1-7) in Mas-transfected Chinese hamster ovary (CHO) cells. Rhodamines 140-149 angiogenin, ribonuclease A family, member 6 Mus musculus 150-158 15351776-1 2004 Extracts of bitter melon, soybean, dokudami and welsh onion by 40% methanol increased the accumulation of rhodamine-123 by Caco-2 cells, suggesting that these extracts inhibited P-glycoprotein (P-gp). Rhodamines 106-115 ATP binding cassette subfamily B member 1 Homo sapiens 178-192 15351776-1 2004 Extracts of bitter melon, soybean, dokudami and welsh onion by 40% methanol increased the accumulation of rhodamine-123 by Caco-2 cells, suggesting that these extracts inhibited P-glycoprotein (P-gp). Rhodamines 106-115 ATP binding cassette subfamily B member 1 Homo sapiens 194-198 15138133-6 2004 The rhodamine extrusion test showed that the percentage of positive cells in MDR(+) cells was significantly lower than that in MDR1(-) cells. Rhodamines 4-13 ATP binding cassette subfamily B member 1 Homo sapiens 127-131 15553233-6 2004 H17 proved to be a better P-gp inhibitor than ritonavir by resulting IC50 values and also in the cellular uptake of rhodamine. Rhodamines 116-125 H1.7 linker histone Homo sapiens 0-3 15158445-12 2004 While Aip2p-treated F-actin in the circular form was negligibly stained by rhodamine-labeled phalloidin (rhodamine-phalloidin) in vitro, rhodamine-phalloidin staining profiles in actin interacting protein 2 gene (AIP2)-modified cells suggested a correlation between the conformation of F-actin and the expression of Aip2p in vivo. Rhodamines 105-114 D-lactate dehydrogenase Saccharomyces cerevisiae S288C 6-11 15158445-12 2004 While Aip2p-treated F-actin in the circular form was negligibly stained by rhodamine-labeled phalloidin (rhodamine-phalloidin) in vitro, rhodamine-phalloidin staining profiles in actin interacting protein 2 gene (AIP2)-modified cells suggested a correlation between the conformation of F-actin and the expression of Aip2p in vivo. Rhodamines 105-114 D-lactate dehydrogenase Saccharomyces cerevisiae S288C 6-11 15201669-2 2004 METHODS: P-gp activity was measured by rhodamine efflux in T-cell subsets from bronchoalveolar lavage (BAL) of five healthy volunteers and 27 lung allograft recipients. Rhodamines 39-48 ATP binding cassette subfamily B member 1 Homo sapiens 9-13 15254709-8 2004 After NS-398 treatment, Western blotting showed reduced P-gp expression and a rhodamine 123 efflux assay demonstrated a significant decrease in P-gp activity. Rhodamines 78-87 ATP binding cassette subfamily B member 1 Homo sapiens 144-148 15020090-4 2004 Another mouse monoclonal IgG (anti-SNAP25), probed with anti-mouse IgG-rhodamine without CARD amplification, selectively visualized synaptic sites, because the maximal dilution of the other monoclonal antibody (anti-calbindin) was below the detection threshold of this anti-mouse IgG-rhodamine. Rhodamines 71-80 synaptosome associated protein 25 Rattus norvegicus 35-41 15020090-4 2004 Another mouse monoclonal IgG (anti-SNAP25), probed with anti-mouse IgG-rhodamine without CARD amplification, selectively visualized synaptic sites, because the maximal dilution of the other monoclonal antibody (anti-calbindin) was below the detection threshold of this anti-mouse IgG-rhodamine. Rhodamines 284-293 synaptosome associated protein 25 Rattus norvegicus 35-41 15134436-7 2004 When GALA was introduced into liposomal membranes using a cholesteryl moiety for anchoring (Chol-GALA), rhodamines were efficiently released and diffused into the cytosol. Rhodamines 104-114 galactosidase alpha Homo sapiens 5-9 15134436-7 2004 When GALA was introduced into liposomal membranes using a cholesteryl moiety for anchoring (Chol-GALA), rhodamines were efficiently released and diffused into the cytosol. Rhodamines 104-114 galactosidase alpha Homo sapiens 97-101 15138133-4 2004 P-gp functions were evaluated through the rhodamine extrusion test. Rhodamines 42-51 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 15102327-3 2004 RESULTS: Visualization of microfilaments in onion bulb scale epidermis cells by different techniques revealed that rhodamine-phalloidin stained F-actin besides cytoplasm also in the nuclei whereas GFP-mouse talin hybrid protein did not enter the nuclei. Rhodamines 115-124 actin Oryctolagus cuniculus 146-151 15050634-4 2004 Eight individual rhodamine labeled peptides were identified that were specific for the kappa opioid receptor, having binding affinities ranging from 5-20 nM. Rhodamines 17-26 opioid receptor kappa 1 Homo sapiens 87-108 15175945-9 2004 Rhodamine-phalloidin staining revealed a decreased number of actin filaments in PK-1 cells treated with troglitazone. Rhodamines 0-9 pyruvate kinase L/R Homo sapiens 80-84 15080706-3 2004 Adsorption of bovine serum albumin (BSA) at silica/aqueous solution interfaces resulted in changes in the polarization state of the frequency-doubled light through weak, dynamic interactions with a coadsorbed nonlinear optical probe molecule (rhodamine 6G). Rhodamines 243-252 albumin Homo sapiens 21-34 15022031-5 2004 As the function of Pgp might be altered in advanced age, we investigated in groups of fit and frail elderly subjects whether the efflux of the Pgp-probe rhodamine 123 from CD56(+) natural killer cells was age dependent and whether it was affected by the two SNPs. Rhodamines 153-162 ATP binding cassette subfamily B member 1 Homo sapiens 143-146 15022031-5 2004 As the function of Pgp might be altered in advanced age, we investigated in groups of fit and frail elderly subjects whether the efflux of the Pgp-probe rhodamine 123 from CD56(+) natural killer cells was age dependent and whether it was affected by the two SNPs. Rhodamines 153-162 neural cell adhesion molecule 1 Homo sapiens 172-176 15022031-8 2004 Using flow cytometry, rhodamine fluorescence was monitored in CD56(+) cells. Rhodamines 22-31 neural cell adhesion molecule 1 Homo sapiens 62-66 15161039-10 2004 The rhodamine uptake was increased in L5178/MDR1 and Colo320/MDR1-LRP, but not drug-sensitive human breast cancer MCF-7 and T47D, and L5178 mouse lymphoma parent cells in the presence of alis-409 and alis-421. Rhodamines 4-13 ATP binding cassette subfamily B member 1 Homo sapiens 44-48 15161039-10 2004 The rhodamine uptake was increased in L5178/MDR1 and Colo320/MDR1-LRP, but not drug-sensitive human breast cancer MCF-7 and T47D, and L5178 mouse lymphoma parent cells in the presence of alis-409 and alis-421. Rhodamines 4-13 ATP binding cassette subfamily B member 1 Homo sapiens 61-65 15040543-12 2004 Basal P-gp-mediated rhodamine efflux was 61.0 +/- 4.2%. Rhodamines 20-29 ATP binding cassette subfamily B member 1 Homo sapiens 6-10 14576174-8 2004 This was further substantiated when we observed colocalization of rhodamine-labeled TSH with TSHR-YFP within the cell and by the uptake of radiolabeled TSH. Rhodamines 66-75 thyroid stimulating hormone receptor Homo sapiens 93-97 15197307-2 2004 Recently, we found that the wild-type Klenow fragment of Escherichia coli DNA polymerase I is well-suited for the synthesis of DNA in a reaction set-up that contains exclusively specific rhodamine-labeled analogs of the natural pyrimidine nucleotides (dCTP and dTTP). Rhodamines 187-196 ttp Drosophila melanogaster 261-265 15301426-8 2004 Imidazole derivatives significantly increased the Dox accumulation and inhibited P-gp function exhibited by the increase of Rhodamine accumulation in MDR cells. Rhodamines 124-133 ATP binding cassette subfamily B member 1 Homo sapiens 81-85 14522974-0 2003 Methanethiosulfonate derivatives of rhodamine and verapamil activate human P-glycoprotein at different sites. Rhodamines 36-45 ATP binding cassette subfamily B member 1 Homo sapiens 75-89 14522974-8 2003 The ATPase activity of MTS-rhodamine-treated mutant F343C, however, was not stimulated further by colchicine or calcein-AM. Rhodamines 27-36 dynein axonemal heavy chain 8 Homo sapiens 4-10 14522974-9 2003 By contrast, verapamil and Hoechst 33342 stimulated and inhibited, respectively, the ATPase activity of the MTS-rhodamine-treated mutant F343C. Rhodamines 112-121 dynein axonemal heavy chain 8 Homo sapiens 85-91 14666249-4 2003 P-glycoprotein function was assessed by the flow cytometric rhodamine 123 assay. Rhodamines 60-69 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 12960034-5 2003 In the present study, rhodamine-labeled (Rho-) BDNF injected into the olfactory bulb was rapidly transferred to neurons in the hlDBB. Rhodamines 22-31 brain derived neurotrophic factor Homo sapiens 47-51 12958156-7 2003 Interestingly, up- or down-regulation of mtCLIC protein expression changes Delta(psi)m whereas the chloride channel inhibitor NPPB reduces the Delta(psi)m in mtDNA-depleted L929 cells, measured with the fluorescent probe rhodamine 123. Rhodamines 221-230 natriuretic peptide B Homo sapiens 126-130 12975485-6 2003 The rhodamine 123 efflux assay showed that the efflux of rhodamine 123 in K562/DXR cells, which overexpress human P-gp, could be blocked markedly by imatinib mesilate in a dose-dependent fashion. Rhodamines 4-13 ATP binding cassette subfamily B member 1 Homo sapiens 114-118 12975485-6 2003 The rhodamine 123 efflux assay showed that the efflux of rhodamine 123 in K562/DXR cells, which overexpress human P-gp, could be blocked markedly by imatinib mesilate in a dose-dependent fashion. Rhodamines 57-66 ATP binding cassette subfamily B member 1 Homo sapiens 114-118 14563317-0 2003 The endoglin(positive) sca-1(positive) rhodamine(low) phenotype defines a near-homogeneous population of long-term repopulating hematopoietic stem cells. Rhodamines 39-48 ataxin 1 Mus musculus 23-28 12801661-6 2003 The nano-SERS fluctuation dynamics were both photo-induced and spontaneous for rhodamine 6G, but only the photo-induced component was observable for cytochrome c. Rhodamines 79-88 seryl-tRNA synthetase 1 Homo sapiens 9-13 12944313-0 2003 Kinetic analysis of rhodamines efflux mediated by the multidrug resistance protein (MRP1). Rhodamines 20-30 ATP binding cassette subfamily C member 1 Homo sapiens 84-88 12944313-3 2003 However, no quantitative studies of the MRP1-mediated efflux of rhodamines have, up to now, been performed. Rhodamines 64-74 ATP binding cassette subfamily C member 1 Homo sapiens 40-44 12944313-7 2003 MRP1-mediated transport of rhodamine was glutathione-dependent. Rhodamines 27-36 ATP binding cassette subfamily C member 1 Homo sapiens 0-4 12944313-8 2003 The kinetics parameter, k(a) = V(M)/k(m), was very similar for the four rhodamine analogs but approximately 10-fold less than the values of the same parameter determined previously for the MRP1-mediated efflux of anthracycline. Rhodamines 72-81 ATP binding cassette subfamily C member 1 Homo sapiens 189-193 12944313-9 2003 The findings presented here are the first to show quantitative information about the kinetics parameters for MRP1-mediated efflux of rhodamine dyes. Rhodamines 133-142 ATP binding cassette subfamily C member 1 Homo sapiens 109-113 14567628-9 2003 A good correlation between Papp and cLogD (pH 7.4) of the compounds tested was observed, except for 3-OMG, AGN 197075, and rhodamine 123, which are substrates of carrier-mediated transport systems such as P-gp and a glucose transporter (GLUT1). Rhodamines 123-132 ATP binding cassette subfamily B member 1 Homo sapiens 205-209 14513313-5 2003 This was established by a cosedimentation assay in cell homogenates and by colocalization of the caldesmon-related immunofluorescence with the fluorescence of filamentous actin stained with rhodamine-labelled phalloidin, demonstrated in optical sections of single cells in a confocal microscope. Rhodamines 190-199 caldesmon 1 Gallus gallus 97-106 12805654-5 2003 PCB 104 increased the oxidative stress in endothelial cells, as determined by the increased 2",7"-dichlorofluorescein (DCF) and rhodamine 123 fluorescence. Rhodamines 128-137 pyruvate carboxylase Homo sapiens 0-3 12896805-1 2003 The hydrophobic estradiol-derivative RU49953 inhibits the energy-dependent interaction of yeast multidrug-transporter Pdr5p with its fluorescent drug-substrate rhodamine 6G. Rhodamines 160-169 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 118-123 14502537-7 2003 Rhodamine 123 efflux was reduced by dexloxiglumide from 4.06 (+/-0.34) to 2.84 (+/-0.15) across Caco-2 monolayers, and from 17.3 (+/-0.9) to 8.26 (+/-1.38) across MDR1-MDCK monolayers, further indicating dexloxiglumide interaction with P-gp. Rhodamines 0-9 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 163-167 14502537-7 2003 Rhodamine 123 efflux was reduced by dexloxiglumide from 4.06 (+/-0.34) to 2.84 (+/-0.15) across Caco-2 monolayers, and from 17.3 (+/-0.9) to 8.26 (+/-1.38) across MDR1-MDCK monolayers, further indicating dexloxiglumide interaction with P-gp. Rhodamines 0-9 phosphoglycolate phosphatase Mus musculus 236-240 12832070-1 2003 We have used fluorescence correlation spectroscopy to analyze the interaction of GTP-tubulin with rhodamine-labeled RB3, a neural protein of the stathmin family, and to determine the kinetic pathway of the association process. Rhodamines 98-107 stathmin 4 Homo sapiens 116-119 12832070-1 2003 We have used fluorescence correlation spectroscopy to analyze the interaction of GTP-tubulin with rhodamine-labeled RB3, a neural protein of the stathmin family, and to determine the kinetic pathway of the association process. Rhodamines 98-107 stathmin 1 Homo sapiens 145-153 12824231-4 2003 Rhodamine-123 (Rho-123), a P-gp substrate, was used as a P-gp probe. Rhodamines 0-9 ATP-dependent translocase ABCB1 Oryctolagus cuniculus 57-61 12626638-0 2003 Examination of the functional activity of P-glycoprotein in the rat placental barrier using rhodamine 123. Rhodamines 92-101 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 42-56 12824231-4 2003 Rhodamine-123 (Rho-123), a P-gp substrate, was used as a P-gp probe. Rhodamines 0-9 ATP-dependent translocase ABCB1 Oryctolagus cuniculus 27-31 12727202-5 2003 Analysis of the mitochondria within the PC-3U cells by polarography and membrane potential-sensitive dye (Rhodamine 123) confirmed that under these experimental conditions, TGF-beta1 inhibited ATP synthesis and depolarised the mitochondria. Rhodamines 106-115 transforming growth factor beta 1 Homo sapiens 173-182 12801910-2 2003 We have characterized the self-assembly of HsRad51 by measuring the fluorescence resonance energy transfer from the fluorescein-labeled protein to the rhodamine-labeled protein. Rhodamines 151-160 RAD51 recombinase Homo sapiens 43-50 12657255-1 2003 Fluorescently labeled histamine H(1) receptor antagonists were synthesized starting from N-demethylmepyramine by introduction of omega-aminoalkyl chains (2-8 methylene groups in length) followed by derivatization of the terminal NH(2) group with various fluorophores (fluorescein, naphthofluorescein, rhodamine, tetramethylrhodamine, BODIPY, dansyl, and nitrobenzoxadiazole (NBD)). Rhodamines 301-310 histamine receptor H1 Homo sapiens 22-45 12703984-13 2003 FACS analysis showed that the concentration of rhodamine 123 was much lower in CNE2/DDP cells than in CNE2 cells (12.98 vs. 243.62). Rhodamines 47-56 translocase of inner mitochondrial membrane 8A Homo sapiens 84-87 12432085-3 2002 Profilin-I-EGFP was distributed throughout the cytoplasm as observed previously with rhodamine-labeled profilin, while EGFP alone accumulated in the nucleus. Rhodamines 85-94 profilin 1 Homo sapiens 0-10 12682648-0 2003 Age-related changes of P-glycoprotein-mediated rhodamine 123 efflux in normal human bone marrow hematopoietic stem cells. Rhodamines 47-56 ATP binding cassette subfamily B member 1 Homo sapiens 23-37 12718873-2 2003 Polarized fluorescence from bifunctional rhodamine probes attached along four alpha helices of troponin C (TnC) was measured in permeabilized skeletal muscle fibers. Rhodamines 41-50 tenascin C Homo sapiens 107-110 12631709-4 2003 Quantitative analysis of colocalization of EGF-rhodamine conjugate and coated pits labeled with yellow-fluorescent-protein-tagged beta2 subunit of clathrin adaptor complex AP-2 revealed that EGFR mutants lacking Grb2 binding sites do not efficiently enter coated pits. Rhodamines 47-56 epidermal growth factor receptor Homo sapiens 191-195 12542697-0 2003 New insights into the P-glycoprotein-mediated effluxes of rhodamines. Rhodamines 58-68 ATP binding cassette subfamily B member 1 Homo sapiens 22-36 12542697-8 2003 The kinetic parameter, ka = VM/km, which is a measure of the efficiency of the P-gp-mediated efflux of a substrate was similar for almost all the rhodamine analogues tested. Rhodamines 146-155 ATP binding cassette subfamily B member 1 Homo sapiens 79-83 12542697-10 2003 Our conclusion is that the compounds of these two classes of molecules, anthracyclines and rhodamines, are substrates of P-gp and that their pumping rates at limiting low substrate concentration are similar. Rhodamines 91-101 ATP binding cassette subfamily B member 1 Homo sapiens 121-125 12542697-11 2003 The findings presented here are the first to show quantitative information about the kinetic parameters for P-gp-mediated efflux of rhodamine analogues in intact cells. Rhodamines 132-141 ATP binding cassette subfamily B member 1 Homo sapiens 108-112 12557277-3 2003 Disruption of PDH1 in a cgcdr1::ura3 strain increased susceptibility to rhodamine 6G, cycloheximide and chloramphenicol, and also increased rhodamine 6G accumulation, all properties of pdr5 null mutants. Rhodamines 72-81 putative 2-methylcitrate dehydratase Saccharomyces cerevisiae S288C 14-18 12557277-3 2003 Disruption of PDH1 in a cgcdr1::ura3 strain increased susceptibility to rhodamine 6G, cycloheximide and chloramphenicol, and also increased rhodamine 6G accumulation, all properties of pdr5 null mutants. Rhodamines 140-149 putative 2-methylcitrate dehydratase Saccharomyces cerevisiae S288C 14-18 12557277-4 2003 Overexpression of PDH1 in S. cerevisiae complemented the pdr5 mutation by reversing susceptibility to rhodamine 6G, chloramphenicol and cycloheximide, as well as by decreasing rhodamine 6G intracellular concentration. Rhodamines 102-111 putative 2-methylcitrate dehydratase Saccharomyces cerevisiae S288C 18-22 12557277-4 2003 Overexpression of PDH1 in S. cerevisiae complemented the pdr5 mutation by reversing susceptibility to rhodamine 6G, chloramphenicol and cycloheximide, as well as by decreasing rhodamine 6G intracellular concentration. Rhodamines 102-111 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 57-61 12557277-4 2003 Overexpression of PDH1 in S. cerevisiae complemented the pdr5 mutation by reversing susceptibility to rhodamine 6G, chloramphenicol and cycloheximide, as well as by decreasing rhodamine 6G intracellular concentration. Rhodamines 176-185 putative 2-methylcitrate dehydratase Saccharomyces cerevisiae S288C 18-22 12557277-4 2003 Overexpression of PDH1 in S. cerevisiae complemented the pdr5 mutation by reversing susceptibility to rhodamine 6G, chloramphenicol and cycloheximide, as well as by decreasing rhodamine 6G intracellular concentration. Rhodamines 176-185 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 57-61 12557277-7 2003 Abundance of PDH1 and CgCDR1 mRNA in C. glabrata was increased by rhodamine 6G, cycloheximide and oligomycin, properties in common with PDR5. Rhodamines 66-75 putative 2-methylcitrate dehydratase Saccharomyces cerevisiae S288C 13-17 14585326-6 2003 Nafoxidine inhibited the Pgp pump activity as measured by rhodamine 123 efflux. Rhodamines 58-67 phosphoglycolate phosphatase Homo sapiens 25-28 12589678-7 2003 Selective localization of fluorescein versus rhodamine fluorescene was observed within GCs following expression of NF-M conjugated to DsRed1-E5, which shifts from fluorescein to rhodamine fluorescence within hours after expression; axonal shafts contained a more even distribution of fluorescein and rhodamine fluorescence, further indicating that GCs contained relatively higher levels of the most-recently expressed subunits. Rhodamines 178-187 neurofilament, medium polypeptide Mus musculus 115-119 12559037-5 2003 On the contrary, rhodamine-labeled bone matrix enters transcytotic vesicles at the central ruffled border, where the vesicle budding proteins such as clathrin, AP-2 and dynamin II are also localized. Rhodamines 17-26 transcription factor AP-2 alpha Homo sapiens 160-164 12559037-5 2003 On the contrary, rhodamine-labeled bone matrix enters transcytotic vesicles at the central ruffled border, where the vesicle budding proteins such as clathrin, AP-2 and dynamin II are also localized. Rhodamines 17-26 dynamin 2 Homo sapiens 169-179 12432340-15 2002 Steady-state rhodamine accumulation was increased in the presence of compounds reported to block P-glycoprotein mediated rhodamine efflux. Rhodamines 13-22 ATP binding cassette subfamily B member 1 Homo sapiens 97-111 12374800-7 2002 The wild-type ABCG2 and its variants, R482G and R482T, showed characteristically different drug and dye transport activities; mitoxantrone and Hoechst 33342 were transported by all transporters, whereas rhodamine 123 was only pumped by the R482G and R482T mutants. Rhodamines 203-212 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 14-19 12223492-3 2002 One class of compounds transported by P-gp is the rhodamine dyes. Rhodamines 50-59 phosphoglycolate phosphatase Homo sapiens 38-42 12223492-4 2002 A P-gp deletion mutant (residues 1-379 plus 681-1025) with only the TM domains retained the ability to bind rhodamine. Rhodamines 108-117 phosphoglycolate phosphatase Homo sapiens 2-6 12432340-15 2002 Steady-state rhodamine accumulation was increased in the presence of compounds reported to block P-glycoprotein mediated rhodamine efflux. Rhodamines 121-130 ATP binding cassette subfamily B member 1 Homo sapiens 97-111 12373300-11 2002 In contrast to DiOC2, rhodamine 123 was not specifically effluxed by P-gp but also by MRP1. Rhodamines 22-31 ATP binding cassette subfamily B member 1 Homo sapiens 69-73 12373300-11 2002 In contrast to DiOC2, rhodamine 123 was not specifically effluxed by P-gp but also by MRP1. Rhodamines 22-31 ATP binding cassette subfamily C member 1 Homo sapiens 86-90 12589934-7 2002 Functional Abcb1a/Abcb1b was detected by inhibition of rhodamine efflux by these drugs and mRNA for Abcb1a and Abcb1b were detected in these cells. Rhodamines 55-64 ATP-binding cassette, sub-family B (MDR/TAP), member 1A Mus musculus 11-17 12417886-5 2002 Der p 1 was labeled with rhodamine. Rhodamines 25-34 crystallin gamma F, pseudogene Homo sapiens 4-7 12417886-7 2002 RESULTS: Rhodamine- labeled Der p 1 was demonstrated to be taken up by MD-DCs in a dose-, time-, and temperature- dependent manner. Rhodamines 9-18 crystallin gamma F, pseudogene Homo sapiens 32-35 12417886-8 2002 The involvement of the mannose receptor (MR) in the Der p 1 uptake was demonstrated by using (1) inhibitors of the MR- mediated endocytosis (mannan and blocking anti-MR mAb), which inhibited the Der p 1 uptake from 40 % to 50 %, and (2) confocal microscopy showing the colocalization of rhodamine-labeled Der p 1 with FITC-dextran. Rhodamines 287-296 mannose receptor C-type 1 Homo sapiens 23-39 12417886-8 2002 The involvement of the mannose receptor (MR) in the Der p 1 uptake was demonstrated by using (1) inhibitors of the MR- mediated endocytosis (mannan and blocking anti-MR mAb), which inhibited the Der p 1 uptake from 40 % to 50 %, and (2) confocal microscopy showing the colocalization of rhodamine-labeled Der p 1 with FITC-dextran. Rhodamines 287-296 mannose receptor C-type 1 Homo sapiens 41-43 12417886-8 2002 The involvement of the mannose receptor (MR) in the Der p 1 uptake was demonstrated by using (1) inhibitors of the MR- mediated endocytosis (mannan and blocking anti-MR mAb), which inhibited the Der p 1 uptake from 40 % to 50 %, and (2) confocal microscopy showing the colocalization of rhodamine-labeled Der p 1 with FITC-dextran. Rhodamines 287-296 crystallin gamma F, pseudogene Homo sapiens 56-59 12417886-8 2002 The involvement of the mannose receptor (MR) in the Der p 1 uptake was demonstrated by using (1) inhibitors of the MR- mediated endocytosis (mannan and blocking anti-MR mAb), which inhibited the Der p 1 uptake from 40 % to 50 %, and (2) confocal microscopy showing the colocalization of rhodamine-labeled Der p 1 with FITC-dextran. Rhodamines 287-296 mannose receptor C-type 1 Homo sapiens 115-117 12417886-8 2002 The involvement of the mannose receptor (MR) in the Der p 1 uptake was demonstrated by using (1) inhibitors of the MR- mediated endocytosis (mannan and blocking anti-MR mAb), which inhibited the Der p 1 uptake from 40 % to 50 %, and (2) confocal microscopy showing the colocalization of rhodamine-labeled Der p 1 with FITC-dextran. Rhodamines 287-296 mannose receptor C-type 1 Homo sapiens 115-117 12417886-8 2002 The involvement of the mannose receptor (MR) in the Der p 1 uptake was demonstrated by using (1) inhibitors of the MR- mediated endocytosis (mannan and blocking anti-MR mAb), which inhibited the Der p 1 uptake from 40 % to 50 %, and (2) confocal microscopy showing the colocalization of rhodamine-labeled Der p 1 with FITC-dextran. Rhodamines 287-296 crystallin gamma F, pseudogene Homo sapiens 199-202 12417886-8 2002 The involvement of the mannose receptor (MR) in the Der p 1 uptake was demonstrated by using (1) inhibitors of the MR- mediated endocytosis (mannan and blocking anti-MR mAb), which inhibited the Der p 1 uptake from 40 % to 50 %, and (2) confocal microscopy showing the colocalization of rhodamine-labeled Der p 1 with FITC-dextran. Rhodamines 287-296 crystallin gamma F, pseudogene Homo sapiens 199-202 12589934-7 2002 Functional Abcb1a/Abcb1b was detected by inhibition of rhodamine efflux by these drugs and mRNA for Abcb1a and Abcb1b were detected in these cells. Rhodamines 55-64 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 18-24 12138126-8 2002 Furthermore, using rhodamine 123 efflux assay we observed a significant increase in P-gp activity in Cox-2 overexpressing renal mesangial cells. Rhodamines 19-28 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 84-88 12138126-8 2002 Furthermore, using rhodamine 123 efflux assay we observed a significant increase in P-gp activity in Cox-2 overexpressing renal mesangial cells. Rhodamines 19-28 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 101-106 12095981-5 2002 The fixation resulted from the interaction with the reactive anchor rhodamine and allowed the quantification of cellular DP IV activity on single cells. Rhodamines 68-77 dipeptidyl peptidase 4 Homo sapiens 121-126 12226838-0 2002 Effect of interferons on P-glycoprotein-mediated rhodamine-123 efflux in cultured rat hepatocytes. Rhodamines 49-58 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 25-39 12095981-6 2002 The reactivity, length, and hydrophobicity of rhodamine was characterized as the decisive factor that facilitated the determination of cellular DP IV activity. Rhodamines 46-55 dipeptidyl peptidase 4 Homo sapiens 144-149 11985312-7 2002 Nile Red and rhodamine 6G molecules prefer the environments of the porous C18 beads. Rhodamines 13-22 Bardet-Biedl syndrome 9 Homo sapiens 74-77 12169628-5 2002 Using rhodamine-labeled LDL, it was possible to demonstrate that during endocytosis, LDL passes through SNX17-positive compartments. Rhodamines 6-15 sorting nexin 17 Homo sapiens 104-109 12160840-0 2002 GATA transcription in a small rhodamine 123(low)CD34(+) subpopulation of a peripheral blood-derived CD34(-)CD105(+) mesenchymal cell line. Rhodamines 30-39 glutaminyl-tRNA amidotransferase subunit QRSL1 Homo sapiens 0-4 12160840-0 2002 GATA transcription in a small rhodamine 123(low)CD34(+) subpopulation of a peripheral blood-derived CD34(-)CD105(+) mesenchymal cell line. Rhodamines 30-39 CD34 molecule Homo sapiens 48-52 12160840-0 2002 GATA transcription in a small rhodamine 123(low)CD34(+) subpopulation of a peripheral blood-derived CD34(-)CD105(+) mesenchymal cell line. Rhodamines 30-39 CD34 molecule Homo sapiens 100-104 12195825-5 2002 After Caco-2 cells were treated with 100 IU mL-1 (6.1 ng mL-1) IL2 for 24 h, a significant diminution (21%) of P-gp transporter function was observed with rhodamine-123 substrate. Rhodamines 155-164 interleukin 2 Homo sapiens 63-66 12195825-5 2002 After Caco-2 cells were treated with 100 IU mL-1 (6.1 ng mL-1) IL2 for 24 h, a significant diminution (21%) of P-gp transporter function was observed with rhodamine-123 substrate. Rhodamines 155-164 ATP binding cassette subfamily B member 1 Homo sapiens 111-115 12126537-8 2002 Rhodamine-123 efflux test showed that the efflux-pump function of P-gp 12 hours after the trransfection was 19.20% in control group, 25.59% in GEM5Zf (+)- MDR1 group, and 35.02% in pT7TS-MDR1 group (all P < 0.01). Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 66-70 12126537-8 2002 Rhodamine-123 efflux test showed that the efflux-pump function of P-gp 12 hours after the trransfection was 19.20% in control group, 25.59% in GEM5Zf (+)- MDR1 group, and 35.02% in pT7TS-MDR1 group (all P < 0.01). Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 155-159 12015757-14 2002 However, rhodamine efflux from CD56-positive cells was not impaired, suggesting poor in vivo Pgp inhibition. Rhodamines 9-18 neural cell adhesion molecule 1 Homo sapiens 31-35 12091325-3 2002 In this study, we evaluated the capacity of 4,5-dibromorhodamine methyl ester (TH9402), a photosensitizer structurally similar to rhodamine, a dye transported by Pgp, and which becomes highly cytotoxic on activation with visible light to selectively deplete alloreactive T lymphocytes. Rhodamines 55-64 ATP binding cassette subfamily B member 1 Homo sapiens 162-165 12398423-7 2002 Rhodamine-labeled chicken vinculin added to permeabilized cells preferentially localized to focal contacts in response to cyclic strain, but not a single step increase in strain. Rhodamines 0-9 vinculin Gallus gallus 26-34 12063025-0 2002 Myeloid-lymphoid initiating cells (ML-IC) are highly enriched in the rhodamine-c-kit(+)CD33(-)CD38(-) fraction of umbilical cord CD34(+) cells. Rhodamines 69-78 KIT proto-oncogene, receptor tyrosine kinase Homo sapiens 79-84 12063025-0 2002 Myeloid-lymphoid initiating cells (ML-IC) are highly enriched in the rhodamine-c-kit(+)CD33(-)CD38(-) fraction of umbilical cord CD34(+) cells. Rhodamines 69-78 CD33 molecule Homo sapiens 87-91 12063025-0 2002 Myeloid-lymphoid initiating cells (ML-IC) are highly enriched in the rhodamine-c-kit(+)CD33(-)CD38(-) fraction of umbilical cord CD34(+) cells. Rhodamines 69-78 CD34 molecule Homo sapiens 129-133 11994059-9 2002 In contrast, P-glycoprotein function was significantly decreased in CD56+ cells of the TT compared with the CC group (rhodamine fluorescence CC vs TT: 45.6+/-7.2% vs 61.1+/-12.3%, P<0.05; 95% CI on the difference 5.6, 25.5). Rhodamines 118-127 ATP binding cassette subfamily B member 1 Homo sapiens 13-27 11864570-4 2002 We fused kinesin to gelsolin, creating a construct that severs and caps rhodamine-phalloidin actin filaments, setting exactly one kinesin molecule on one end of each fluorescent actin filament. Rhodamines 72-81 gelsolin Homo sapiens 20-28 11945073-10 2002 TSA accelerated and glucocorticoid blocked export of rhodamine 123, a molecule known to be exported by PGP. Rhodamines 53-62 ATP binding cassette subfamily B member 1 Homo sapiens 103-106 11849198-12 2002 P-glycoprotein mediated drug efflux was determined as a function of rhodamine efflux in the absence and presence of ritonavir. Rhodamines 68-77 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 11849198-19 2002 Ritonavir (5 microm) inhibited P-glycoprotein mediated efflux in both groups producing greater intracellular accumulation of rhodamine. Rhodamines 125-134 ATP binding cassette subfamily B member 1 Homo sapiens 31-45 11559526-5 2001 A vaccinia virus expression system confirmed that rhodamine as well as doxorubicin efflux is observed with R482T or R482G but not with the wild-type R482; all three MXR/BCRP/ABCP forms transported mitoxantrone. Rhodamines 50-59 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 165-168 11840269-4 2002 MDR-1 (but not tNGFR) expression was associated with verapamil-sensitive rhodamine efflux and resistance to killing by etoposide. Rhodamines 73-82 malic enzyme complex, mitochondrial Mus musculus 0-5 11717390-0 2001 Global configuration of single titin molecules observed through chain-associated rhodamine dimers. Rhodamines 81-90 titin Homo sapiens 31-36 11717390-1 2001 The global configuration of individual, surface-adsorbed molecules of the giant muscle protein titin, labeled with rhodamine conjugates, was followed with confocal microscopy. Rhodamines 115-124 titin Homo sapiens 95-100 11801536-3 2002 Previous studies have shown that pluripotent hematopoietic stem cells overexpress the multidrug-resistant transport (MDR1) gene and efflux rhodamine, a substrate for the MDR1 transporter. Rhodamines 139-148 ATP binding cassette subfamily B member 1 Homo sapiens 117-121 11801536-3 2002 Previous studies have shown that pluripotent hematopoietic stem cells overexpress the multidrug-resistant transport (MDR1) gene and efflux rhodamine, a substrate for the MDR1 transporter. Rhodamines 139-148 ATP binding cassette subfamily B member 1 Homo sapiens 170-174 11990784-7 2002 Furthermore, CD56+ cells obtained from patients treated with PSC 833 demonstrate enhanced rhodamine retention in an ex vivo assay after administration of the antagonist. Rhodamines 90-99 neural cell adhesion molecule 1 Homo sapiens 13-17 11757906-3 2001 Confocal microscopy with Hsp 25-antibody and rhodamine-labeled phalloidin clearly demonstrated the co-localization of Hsp 25 and actin filaments in the ameloblast layer, supporting our hypothesis that this molecule might serve to reinforce the ameloblast layer during enamel formation as well as the formation and maintenance of the ruffled border in ruffle-ended ameloblasts. Rhodamines 45-54 heat shock protein family B (small) member 1 Rattus norvegicus 118-124 11585750-7 2001 Confocal fluorescence microscopy of tumor cells incubated with a rhodamine conjugate of the thermally responsive ELP showed that the cytoplasm was uniformly stained below the T(t). Rhodamines 65-74 nuclear receptor subfamily 5 group A member 1 Homo sapiens 113-116 11587212-4 2001 P-gp and MRP activity varied strongly between the cases (rhodamine 123 efflux-blocking by PSC833: 5.4+/-7.7, and carboxyfluorescein efflux-blocking by MK-571: 4.3+/-6.7, n = 60). Rhodamines 57-66 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 11587212-4 2001 P-gp and MRP activity varied strongly between the cases (rhodamine 123 efflux-blocking by PSC833: 5.4+/-7.7, and carboxyfluorescein efflux-blocking by MK-571: 4.3+/-6.7, n = 60). Rhodamines 57-66 ATP binding cassette subfamily C member 1 Homo sapiens 9-12 11745237-12 2001 Ten patients studied at the MTD for PSC 833 (4 mg/kg orally every 6 hours for 8 days) had inhibition of rhodamine efflux from CD56 positive peripheral lymphocytes as a surrogate for Pgp antagonism. Rhodamines 104-113 neural cell adhesion molecule 1 Homo sapiens 126-130 11559526-5 2001 A vaccinia virus expression system confirmed that rhodamine as well as doxorubicin efflux is observed with R482T or R482G but not with the wild-type R482; all three MXR/BCRP/ABCP forms transported mitoxantrone. Rhodamines 50-59 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 169-173 11559526-5 2001 A vaccinia virus expression system confirmed that rhodamine as well as doxorubicin efflux is observed with R482T or R482G but not with the wild-type R482; all three MXR/BCRP/ABCP forms transported mitoxantrone. Rhodamines 50-59 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 174-178 11502585-5 2001 SIN-1-mediated ONOO(-) formation was confirmed by monitoring the oxidation of dihydrorhodamine 123 to rhodamine. Rhodamines 85-94 MAPK associated protein 1 Homo sapiens 0-5 11515543-8 2001 In addition, accumulation of rhodamine 6G in the cells was detected as a result of Pdr5 inhibition by FK506. Rhodamines 29-38 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 83-87 11518803-3 2001 After 5 min, the beta-arrestin-green fluorescent protein conjugate was visible in vesicles, where it colocalized with rhodamine-labeled TRH. Rhodamines 118-127 thyrotropin releasing hormone Homo sapiens 136-139 11477162-6 2001 RESULTS: A decrease of intestinal rhodamine 123 transport was observed in chronic renal failure rats, pointing to an inhibition of P-glycoprotein activity. Rhodamines 34-43 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 131-145 11477162-9 2001 CONCLUSIONS: Intestinal secretion of rhodamine 123 is mainly mediated by P-glycoprotein. Rhodamines 37-46 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 73-87 11237063-7 2001 With a functional rhodamine retention assay using the modulator PSC833, increased MDR1 activity was observed in the -7/7q- group as compared to the control group of patients (P = 0.05). Rhodamines 18-27 ATP binding cassette subfamily B member 1 Homo sapiens 82-86 11445244-9 2001 EP 51389 inhibited P-gp in a dose dependent manner resulting in the intracellular accumulation of rhodamine in CH(R)C5 cells. Rhodamines 98-107 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 19-23 11428664-7 2001 In Caco-2 cells, plasma collected from CCl4-treated rats exhibited a greater inhibitory effect on P-glycoprotein-mediated transport of rhodamine 123 than that from control rats, suggesting the accumulation of an endogenous P-glycoprotein substrate/inhibitor in the plasma of diseased rats. Rhodamines 135-144 C-C motif chemokine ligand 4 Homo sapiens 39-43 11428664-7 2001 In Caco-2 cells, plasma collected from CCl4-treated rats exhibited a greater inhibitory effect on P-glycoprotein-mediated transport of rhodamine 123 than that from control rats, suggesting the accumulation of an endogenous P-glycoprotein substrate/inhibitor in the plasma of diseased rats. Rhodamines 135-144 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 98-112 11428664-7 2001 In Caco-2 cells, plasma collected from CCl4-treated rats exhibited a greater inhibitory effect on P-glycoprotein-mediated transport of rhodamine 123 than that from control rats, suggesting the accumulation of an endogenous P-glycoprotein substrate/inhibitor in the plasma of diseased rats. Rhodamines 135-144 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 223-237 11389438-3 2001 Here we demonstrate for the first time that both CapZ and Tmod are dynamic on the basis of the rapid incorporation of microinjected rhodamine-labelled actin (rho-actin) at both barbed and pointed ends and from the photobleaching of green fluorescent protein (GFP)-labelled Tmod. Rhodamines 132-141 capping actin protein of muscle Z-line subunit alpha 2 Homo sapiens 49-53 11389438-3 2001 Here we demonstrate for the first time that both CapZ and Tmod are dynamic on the basis of the rapid incorporation of microinjected rhodamine-labelled actin (rho-actin) at both barbed and pointed ends and from the photobleaching of green fluorescent protein (GFP)-labelled Tmod. Rhodamines 132-141 tropomodulin 1 Homo sapiens 58-62 11434506-10 2001 Subjects with CC genotype revealed a significantly lower rhodamine fluorescence (i.e. higher PGP function) compared to individuals with TT genotype (51.1 +/- 11.4% versus 67.5 +/- 9.5%, p < 0.01). Rhodamines 57-66 ATP binding cassette subfamily B member 1 Homo sapiens 93-96 11434506-13 2001 In summary, subjects being homozygous for C in position 3435 of the MDR1 gene have a more pronounced efflux of rhodamine from CD56+ natural killer cells and a higher MDR1 mRNA expression in leukocytes than subjects with the TT genotype. Rhodamines 111-120 ATP binding cassette subfamily B member 1 Homo sapiens 68-72 11434506-14 2001 Measurement of rhodamine efflux using flow-cytometry from peripheral blood cells allows assessment of genetically determined differences in P-glycoprotein function. Rhodamines 15-24 ATP binding cassette subfamily B member 1 Homo sapiens 140-154 11406763-5 2001 While interleukin-3-containing factor combinations promoted cell proliferation they caused loss of rhodamine-123 extrusion and reduced the frequencies of cobblestone area-forming cells (CAFC). Rhodamines 99-108 interleukin 3 Homo sapiens 6-19 11877073-7 2001 Rhodamine 123 efflux showed 16% transduced cells with P-gp function. Rhodamines 0-9 phosphoglycolate phosphatase Homo sapiens 54-58 11347883-2 2001 The specificity of the binding was attested by the consistent displacement of bound rhodamine-labeled EGF (Rh-EGF) following addition of 1000-fold molar excess of unlabeled EGF. Rhodamines 84-93 epidermal growth factor Homo sapiens 102-105 11347883-2 2001 The specificity of the binding was attested by the consistent displacement of bound rhodamine-labeled EGF (Rh-EGF) following addition of 1000-fold molar excess of unlabeled EGF. Rhodamines 84-93 epidermal growth factor Homo sapiens 110-113 11347883-2 2001 The specificity of the binding was attested by the consistent displacement of bound rhodamine-labeled EGF (Rh-EGF) following addition of 1000-fold molar excess of unlabeled EGF. Rhodamines 84-93 epidermal growth factor Homo sapiens 110-113 11327879-6 2001 A direct correlation is obtained between the efficiencies of PKC effectors to inhibit energy-dependent interaction of rhodamine 6G with yeast Pdr5p, to promote intracellular drug accumulation in various multidrug resistant cells, and to chemosensitize growth of resistant cells. Rhodamines 118-127 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 142-147 11162533-2 2001 Using fluorescence correlation spectroscopy, we have studied binding of rhodamine-labelled human C-peptide to intact human skin fibroblasts and to detergent-solubilised extracts of fibroblasts, K-562, and IEC-6 cells. Rhodamines 72-81 insulin Homo sapiens 97-106 11162533-3 2001 Specificity was shown by displacement of rhodamine-labelled human C-peptide with unlabelled human C-peptide. Rhodamines 41-50 insulin Homo sapiens 66-75 11162533-3 2001 Specificity was shown by displacement of rhodamine-labelled human C-peptide with unlabelled human C-peptide. Rhodamines 41-50 insulin Homo sapiens 98-107 11212278-8 2001 Accumulation and efflux studies with the P-gp substrates, [3H]daunorubicin and rhodamine 123, demonstrated that XR9576 inhibited P-gp-mediated drug efflux. Rhodamines 79-88 phosphoglycolate phosphatase Mus musculus 129-133 11205902-3 2001 Flavopiridol at a concentration of 10 microM was able to prevent MRP-mediated calcein efflux, whereas Pgp-mediated transport of rhodamine 123 was unaffected at flavopiridol concentrations of up to 100 microM. Rhodamines 128-137 phosphoglycolate phosphatase Homo sapiens 102-105 10944537-3 2000 Here the specific interaction between Tat protein, human cyclin T1, and HIV-1 TAR RNA was analyzed by fluorescence resonance energy transfer, using fluorescein-labeled TAR RNA and a rhodamine-labeled Tat protein synthesized through solid-phase chemistry. Rhodamines 182-191 cyclin T1 Homo sapiens 57-66 10956648-8 2000 rHDL containing only acceptor probe-labeled Q132C apoA-I showed rhodamine self-quenching. Rhodamines 64-73 apolipoprotein A1 Homo sapiens 50-56 11104578-11 2000 Finally, it is revealed that these novel taxanes have ability to inhibit the function of the P-gp efflux pump on the basis of the Rhodamine 123 assay. Rhodamines 130-139 ATP binding cassette subfamily B member 1 Homo sapiens 93-97 10944537-3 2000 Here the specific interaction between Tat protein, human cyclin T1, and HIV-1 TAR RNA was analyzed by fluorescence resonance energy transfer, using fluorescein-labeled TAR RNA and a rhodamine-labeled Tat protein synthesized through solid-phase chemistry. Rhodamines 182-191 RNA binding motif protein 8A Homo sapiens 78-81 11073100-14 2000 J774 macrophages that expressed GFP-rab5a:wt showed transiently activation and recruitment of GFP-rab5a:wt to newly formed phagosomes that contained rhodamine-labeled Escherichia coli. Rhodamines 149-158 RAB5A, member RAS oncogene family Mus musculus 36-41 11073100-14 2000 J774 macrophages that expressed GFP-rab5a:wt showed transiently activation and recruitment of GFP-rab5a:wt to newly formed phagosomes that contained rhodamine-labeled Escherichia coli. Rhodamines 149-158 RAB5A, member RAS oncogene family Mus musculus 98-103 11218898-3 2000 The positive rate and function of the mdr1 gene product P-glycoprotein (P-gp) in SKOV3/mdr1 cells after mdr1-ASON (250 micrograms/ml) treatment were determined by flow cytometry and rhodamine 123 efflux trial. Rhodamines 182-191 ATP binding cassette subfamily B member 1 Homo sapiens 38-42 11218898-3 2000 The positive rate and function of the mdr1 gene product P-glycoprotein (P-gp) in SKOV3/mdr1 cells after mdr1-ASON (250 micrograms/ml) treatment were determined by flow cytometry and rhodamine 123 efflux trial. Rhodamines 182-191 ATP binding cassette subfamily B member 1 Homo sapiens 56-70 11235562-4 2000 The functional activity of mdr1 in transfected cells was examined by rhodamine retention assay. Rhodamines 69-78 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 27-31 11218898-3 2000 The positive rate and function of the mdr1 gene product P-glycoprotein (P-gp) in SKOV3/mdr1 cells after mdr1-ASON (250 micrograms/ml) treatment were determined by flow cytometry and rhodamine 123 efflux trial. Rhodamines 182-191 ATP binding cassette subfamily B member 1 Homo sapiens 72-76 11218898-6 2000 Intracellular rhodamine retension in SKOV3/mdr1 cells after mdr1-ASON treatment was increased from 32.1% to 50.7% (P < 0.01). Rhodamines 14-23 ATP binding cassette subfamily B member 1 Homo sapiens 43-47 11218898-6 2000 Intracellular rhodamine retension in SKOV3/mdr1 cells after mdr1-ASON treatment was increased from 32.1% to 50.7% (P < 0.01). Rhodamines 14-23 ATP binding cassette subfamily B member 1 Homo sapiens 60-64 11040353-2 2000 The in vivo function of P-glycoprotein was evaluated by measuring renal secretory and biliary clearance and brain distribution of rhodamine 123 (Rho-123), a P-glycoprotein substrate, under a steady-state plasma concentration. Rhodamines 130-139 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 24-38 10930530-0 2000 Expression, maturation, and rhodamine-based fluorescence assay of human cathepsin K expressed in CHO cells. Rhodamines 28-37 cathepsin K Homo sapiens 72-83 11073069-8 2000 The subcellular localization of Hsp 25-immunoreactivity in this study appeared essentially identical to that of actin filaments as demonstrated by confocal microscopy using rhodamine-labeled phalloidin. Rhodamines 173-182 heat shock protein family B (small) member 1 Rattus norvegicus 32-38 10882736-7 2000 This internalization was strongly inhibited by hypertonic medium (0.45 m sucrose) and paralleled localization of rhodamine-labeled transferrin, suggesting that CRLR endocytosis occurred predominantly through a clathrin-dependent pathway. Rhodamines 113-122 calcitonin receptor like receptor Homo sapiens 160-164 10882736-9 2000 In HEK 293 cells stably expressing CRLR-GFP and Myc-RAMPs, these rhodamine-labeled RAMPs were co-localized with CRLR-GFP in the presence and absence of the ligands. Rhodamines 65-74 calcitonin receptor like receptor Homo sapiens 35-39 10882736-9 2000 In HEK 293 cells stably expressing CRLR-GFP and Myc-RAMPs, these rhodamine-labeled RAMPs were co-localized with CRLR-GFP in the presence and absence of the ligands. Rhodamines 65-74 calcitonin receptor like receptor Homo sapiens 112-116 10930530-6 2000 The intracellular activity of cathepsin K was monitored by FACS analysis using the rhodamine substrate, which demonstrated an increased fluorescence over mock-transfected cells that was also inhibitable by (2S,3S)-trans-epoxysuccinyl-L-leucylamido-3-methylbutane ethyl ester (E64d). Rhodamines 83-92 cathepsin K Cricetulus griseus 30-41 11129093-7 2000 P-gp activity was determined by flow cytometry with rhodamine 123 efflux. Rhodamines 52-61 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 11004584-1 2000 Among various dyes including congo red, thioflavin S, thioflavin T, eosin, rhodamine 6G, and phenol red, the eosin was the only dye that induced self-oligomerization of alpha-synuclein in the presence of a chemical coupling reagent of N-(ethoxycarbonyl)-2-ethoxy-1, 2-dihydroquinoline. Rhodamines 75-84 synuclein alpha Homo sapiens 169-184 10689111-6 2000 Two color confocal microscopy performed on fixed, permeabilized cells further showed that the EGFP green fluorescence co-localized with anti-calnexin rhodamine fluorescence in the four HLA-G isoform transfectants but only in HLA-G1 transfectant was the green EGFP fluorescence also detectable at the outer part of the cells, suggesting that the HLA-G2, -G3, and G4 were retained in the endoplasmic reticulum. Rhodamines 150-159 major histocompatibility complex, class I, G Homo sapiens 185-190 10903136-7 2000 To confirm a direct interaction of EGF1 with APC, rhodamine was covalently attached to the alpha-N-terminus of EGF1, and binding of the labelled EGF1 to APC was directly demonstrated using FRET. Rhodamines 50-59 G elongation factor mitochondrial 1 Homo sapiens 35-39 10903136-7 2000 To confirm a direct interaction of EGF1 with APC, rhodamine was covalently attached to the alpha-N-terminus of EGF1, and binding of the labelled EGF1 to APC was directly demonstrated using FRET. Rhodamines 50-59 G elongation factor mitochondrial 1 Homo sapiens 111-115 10903136-7 2000 To confirm a direct interaction of EGF1 with APC, rhodamine was covalently attached to the alpha-N-terminus of EGF1, and binding of the labelled EGF1 to APC was directly demonstrated using FRET. Rhodamines 50-59 G elongation factor mitochondrial 1 Homo sapiens 111-115 11051045-6 2000 Using rhodamine-labeled PRL, we observed specific PRL uptake by these cells that suggested the presence of a PRL receptor. Rhodamines 6-15 prolactin Homo sapiens 24-27 11051045-6 2000 Using rhodamine-labeled PRL, we observed specific PRL uptake by these cells that suggested the presence of a PRL receptor. Rhodamines 6-15 prolactin Homo sapiens 50-53 11051045-6 2000 Using rhodamine-labeled PRL, we observed specific PRL uptake by these cells that suggested the presence of a PRL receptor. Rhodamines 6-15 prolactin receptor Homo sapiens 109-121 10863218-5 2000 Granular staining for alpha5beta1 with fluorescein and smooth staining for fibronectin with rhodamine were seen at the periphery of the AP muscle bundles and along the distal fibers. Rhodamines 92-101 fibronectin 1 Homo sapiens 75-86 10841772-6 2000 The extent of high-affinity binding of prenyl-flavonoids to purified Pdr5p was correlated to their efficiency to inhibit energy-dependent quenching of rhodamine 6G fluorescence catalyzed by Pdr5p-enriched plasma membranes. Rhodamines 151-160 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 69-74 10841772-6 2000 The extent of high-affinity binding of prenyl-flavonoids to purified Pdr5p was correlated to their efficiency to inhibit energy-dependent quenching of rhodamine 6G fluorescence catalyzed by Pdr5p-enriched plasma membranes. Rhodamines 151-160 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 190-195 11778227-4 2000 RESULTS: Transduction of mdr1 ribozyme to A549/R cells led to decrease in mdr1 mRNA and Pgp expression; increase in rhodamine accumulation. Rhodamines 116-125 ATP binding cassette subfamily B member 1 Homo sapiens 25-29 10726660-2 2000 The oligoribonucleotide, rC11U2C7, was labeled covalently at its 5"-terminus with fluorescein and at its 3"-terminus with rhodamine to provide a substrate for RNase L. Rhodamines 122-131 ribonuclease L Homo sapiens 159-166 10712705-3 2000 A T1364F mutation leads to a reduction in Pdr5p-mediated azole and rhodamine 6G resistance. Rhodamines 67-76 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 42-47 10502397-1 1999 Cultured embryonic chicken skeletal muscle cells microinjected with rhodamine (rh)-labeled actin were stained with antibodies against nebulin and connectin (titin). Rhodamines 68-77 actin, beta Gallus gallus 91-96 10620493-4 2000 GFP-neurabin-II labels only a subset of F-actin within these cells, as indicated by rhodamine-phalloidin staining. Rhodamines 84-93 protein phosphatase 1, regulatory subunit 9B Rattus norvegicus 4-15 10631002-5 2000 A rhodamine-labeled geranylgeranylated/methylated cysteine derivative is used to measure its binding to rhoGDI. Rhodamines 2-11 Rho GDP dissociation inhibitor alpha Homo sapiens 104-110 10585262-3 1999 These two agents inhibited the Pgp function (rhodamine-123 excretion) as well as cell-mediated cytotoxicity, confirming that Pgp is critical for NK cell-mediated cytotoxicity. Rhodamines 45-54 ATP binding cassette subfamily B member 1 Homo sapiens 125-128 10537179-8 1999 IF microscopy of filamentous actin using rhodamine-conjugated phalloidin revealed a significant and rapid generation of both membrane ruffling and stress fibers in response to PRL, an effect inhibited by the phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002. Rhodamines 41-50 prolactin Homo sapiens 176-179 10560911-7 1999 The effects of MIP-1alpha were inhibited by blocking antibodies to integrin alpha4, alpha5, or beta1, and polymerization plus rearrangement of F-actin were observed in affected cells by labeling with rhodamine-conjugated phalloidine. Rhodamines 200-209 C-C motif chemokine ligand 3 Homo sapiens 15-25 10541289-7 1999 This study found: (1) PAF C-16 and analogs inhibited Pgp-mediated efflux of rhodamine 123 by 59 to 88% in multidrug-resistant KBV-1 cells and by 85 to 97% in cultured human mesangial cells. Rhodamines 76-85 phosphoglycolate phosphatase Homo sapiens 53-56 10523513-6 1999 Profilin-II labeled with rhodamine on cysteine at position 58 retains its affinity for actin, PIP(2) and poly-L-proline. Rhodamines 25-34 profilin 2 Homo sapiens 0-11 10523513-6 1999 Profilin-II labeled with rhodamine on cysteine at position 58 retains its affinity for actin, PIP(2) and poly-L-proline. Rhodamines 25-34 prolactin induced protein Homo sapiens 94-97 10502397-1 1999 Cultured embryonic chicken skeletal muscle cells microinjected with rhodamine (rh)-labeled actin were stained with antibodies against nebulin and connectin (titin). Rhodamines 68-70 actin, beta Gallus gallus 91-96 10498614-3 1999 Normal CD34(+) progenitors showed rhodamine efflux in 20% to 30% of the cells, which could be blocked by verapamil. Rhodamines 34-43 CD34 molecule Homo sapiens 7-11 10498614-6 1999 Triggering rhodamine dull (RhoD) CD34(+) cells to proliferate indeed resulted in a higher rhodamine retention and significantly decreased efflux modulation by verapamil (P =.04). Rhodamines 11-20 CD34 molecule Homo sapiens 33-37 10498614-6 1999 Triggering rhodamine dull (RhoD) CD34(+) cells to proliferate indeed resulted in a higher rhodamine retention and significantly decreased efflux modulation by verapamil (P =.04). Rhodamines 90-99 CD34 molecule Homo sapiens 33-37 11776553-3 1999 Pgp, a product of mdr1 gene expression, and its function were detected by flow cytometry, immunohistochemistry, and rhodamine test respectively. Rhodamines 116-125 phosphoglycolate phosphatase Mus musculus 0-3 11776553-3 1999 Pgp, a product of mdr1 gene expression, and its function were detected by flow cytometry, immunohistochemistry, and rhodamine test respectively. Rhodamines 116-125 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 18-22 10496651-1 1999 PURPOSE: Previous studies demonstrated that inhibition of P glycoprotein (P-gp) by Pluronic P85 (P85) block copolymer increases apical (AP) to basolateral (BL) transport of rhodamine 123 (R123) in the polarized monolayers of bovine brain microvessel endothelial cells (BBMEC) and Caco-2 cells. Rhodamines 173-182 phosphoglycolate phosphatase Bos taurus 58-72 10496651-1 1999 PURPOSE: Previous studies demonstrated that inhibition of P glycoprotein (P-gp) by Pluronic P85 (P85) block copolymer increases apical (AP) to basolateral (BL) transport of rhodamine 123 (R123) in the polarized monolayers of bovine brain microvessel endothelial cells (BBMEC) and Caco-2 cells. Rhodamines 173-182 phosphoglycolate phosphatase Bos taurus 74-78 10496651-1 1999 PURPOSE: Previous studies demonstrated that inhibition of P glycoprotein (P-gp) by Pluronic P85 (P85) block copolymer increases apical (AP) to basolateral (BL) transport of rhodamine 123 (R123) in the polarized monolayers of bovine brain microvessel endothelial cells (BBMEC) and Caco-2 cells. Rhodamines 173-182 phosphoinositide-3-kinase regulatory subunit 2 Homo sapiens 92-95 10496651-1 1999 PURPOSE: Previous studies demonstrated that inhibition of P glycoprotein (P-gp) by Pluronic P85 (P85) block copolymer increases apical (AP) to basolateral (BL) transport of rhodamine 123 (R123) in the polarized monolayers of bovine brain microvessel endothelial cells (BBMEC) and Caco-2 cells. Rhodamines 173-182 phosphoinositide-3-kinase regulatory subunit 2 Homo sapiens 97-100 10438534-14 1999 Overexpression of pABC11 resulted in reduced labeling with the fluorochromes 5-chloromethylfluorescein diacetate, fluorescein diacetate, and 2",7"-bis-(2-carboxyethyl)-5 (and-6)-carboxyfluorescein acetoxymethyl ester but not with calcein or rhodamine derivatives, consistent with pABC11 being an anion transporter. Rhodamines 241-250 ATP binding cassette subfamily C member 5 Homo sapiens 18-24 10361105-5 1999 Pgp expression and function were analyzed by flow cytometric analysis of MRK 16 binding and Rhodamine 123 retention, respectively. Rhodamines 92-101 ATP binding cassette subfamily B member 1 Homo sapiens 0-3 10379790-10 1999 Rhodamine efflux correlated with MDR-1 mRNA expression (r = 0.87) and with the IC50s (r = 0.60) for paclitaxel in the paired cell lines. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 33-38 9972801-9 1999 Rhodamine-labeled microspheres were identified in VIP-containing nerve cell bodies of the ferret tracheal plexus. Rhodamines 0-9 VIP peptides Mustela putorius furo 50-53 10336475-4 1999 A rhodamine-labeled TRH analog and fluorescein-labeled transferrin co-localized in endocytic vesicles in Fq/11 cells, indicating that endocytosis took place via the normal clathrin pathway. Rhodamines 2-11 thyrotropin releasing hormone Mus musculus 20-23 10212205-3 1999 Fluorescence resonance energy transfer (FRET) experiments were performed in the present study to investigate structural changes that accompany complex formation between the HMG domain B of HMG1 and a cisplatin-modified, 20-base pair double-stranded DNA probe containing fluorescein and rhodamine tethered at its two ends. Rhodamines 286-295 high mobility group box 1 pseudogene 5 Homo sapiens 189-193 10471992-6 1999 CFM revealed that rhodamine-labeled intact caldesmon and the 20-kDa caldesmon fragment bind along nearly the entire length of the thin filaments. Rhodamines 18-27 caldesmon Oryctolagus cuniculus 43-52 10195430-3 1999 Functional expression of Cmdr1 in both mouse NIH 3T3 and yeast cells demonstrated that Cmdr1 represents the avian ortholog of human Mdr1, since it confers resistance to several anticancer drugs and the fluorescent dye rhodamine 6G. Rhodamines 218-227 ATP binding cassette subfamily B member 1 Gallus gallus 25-30 10195430-3 1999 Functional expression of Cmdr1 in both mouse NIH 3T3 and yeast cells demonstrated that Cmdr1 represents the avian ortholog of human Mdr1, since it confers resistance to several anticancer drugs and the fluorescent dye rhodamine 6G. Rhodamines 218-227 ATP binding cassette subfamily B member 1 Gallus gallus 87-92 10195430-3 1999 Functional expression of Cmdr1 in both mouse NIH 3T3 and yeast cells demonstrated that Cmdr1 represents the avian ortholog of human Mdr1, since it confers resistance to several anticancer drugs and the fluorescent dye rhodamine 6G. Rhodamines 218-227 ATP binding cassette subfamily B member 1 Homo sapiens 132-136 10195430-8 1999 Indeed, competition experiments indicated that Cmdr1 interacts with estradiol, since rhodamine 6G efflux was efficiently blocked by estradiol in NIH 3T3 cells expressing Cmdr1. Rhodamines 85-94 ATP binding cassette subfamily B member 1 Gallus gallus 47-52 10195430-8 1999 Indeed, competition experiments indicated that Cmdr1 interacts with estradiol, since rhodamine 6G efflux was efficiently blocked by estradiol in NIH 3T3 cells expressing Cmdr1. Rhodamines 85-94 ATP binding cassette subfamily B member 1 Gallus gallus 170-175 9858256-6 1998 The introduction of constitutively active Rac1 resulted in an increase in rhodamine-phalloidin staining, presumably from an accumulation of actin filaments in growth cones, while dominant negative Rac1 caused a decrease in rhodamine-phalloidin staining. Rhodamines 74-83 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Gallus gallus 42-46 9920827-9 1999 P-gp function was assessed in 19 patients using rhodamine-123 efflux and its inhibition by PSC. Rhodamines 48-57 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 9920827-10 1999 The median percentage of blasts expressing P-gp was increased (49%) for leukemic cells with PSC-inhibitable rhodamine efflux compared with 17% in cases lacking PSC-inhibitable efflux (P =.004). Rhodamines 108-117 ATP binding cassette subfamily B member 1 Homo sapiens 43-47 9891078-5 1999 Using an approach involving exchanging homologous segments of MDR1 and MDR2 and site-directed mutagenesis, we have demonstrated that MDR1 residues Q330, V331, and L332 in transmembrane domain 6 are sufficient to allow an MDR2 backbone in the N-terminal half of P-gp to transport several MDR1 substrates, including bisantrene, colchicine, vinblastine, and rhodamine-123. Rhodamines 355-364 ATP binding cassette subfamily B member 1 Homo sapiens 62-66 9891078-5 1999 Using an approach involving exchanging homologous segments of MDR1 and MDR2 and site-directed mutagenesis, we have demonstrated that MDR1 residues Q330, V331, and L332 in transmembrane domain 6 are sufficient to allow an MDR2 backbone in the N-terminal half of P-gp to transport several MDR1 substrates, including bisantrene, colchicine, vinblastine, and rhodamine-123. Rhodamines 355-364 ATP binding cassette subfamily B member 4 Homo sapiens 71-75 9891078-5 1999 Using an approach involving exchanging homologous segments of MDR1 and MDR2 and site-directed mutagenesis, we have demonstrated that MDR1 residues Q330, V331, and L332 in transmembrane domain 6 are sufficient to allow an MDR2 backbone in the N-terminal half of P-gp to transport several MDR1 substrates, including bisantrene, colchicine, vinblastine, and rhodamine-123. Rhodamines 355-364 ATP binding cassette subfamily B member 1 Homo sapiens 133-137 9891078-5 1999 Using an approach involving exchanging homologous segments of MDR1 and MDR2 and site-directed mutagenesis, we have demonstrated that MDR1 residues Q330, V331, and L332 in transmembrane domain 6 are sufficient to allow an MDR2 backbone in the N-terminal half of P-gp to transport several MDR1 substrates, including bisantrene, colchicine, vinblastine, and rhodamine-123. Rhodamines 355-364 ATP binding cassette subfamily B member 4 Homo sapiens 221-225 9891078-5 1999 Using an approach involving exchanging homologous segments of MDR1 and MDR2 and site-directed mutagenesis, we have demonstrated that MDR1 residues Q330, V331, and L332 in transmembrane domain 6 are sufficient to allow an MDR2 backbone in the N-terminal half of P-gp to transport several MDR1 substrates, including bisantrene, colchicine, vinblastine, and rhodamine-123. Rhodamines 355-364 ATP binding cassette subfamily B member 1 Homo sapiens 261-265 9891078-5 1999 Using an approach involving exchanging homologous segments of MDR1 and MDR2 and site-directed mutagenesis, we have demonstrated that MDR1 residues Q330, V331, and L332 in transmembrane domain 6 are sufficient to allow an MDR2 backbone in the N-terminal half of P-gp to transport several MDR1 substrates, including bisantrene, colchicine, vinblastine, and rhodamine-123. Rhodamines 355-364 ATP binding cassette subfamily B member 1 Homo sapiens 133-137 10465451-4 1999 In six cases with injections restricted to the supraoptic nucleus, rhodamine-labelled microspheres were observed in a population of tyrosine hydroxylase-positive neurons located in the A15 cells below the anterior commissure (A15 dorsal) and above the optic chiasm (A15 ventral), and the dorsal and lateral periventricular A14 cell group. Rhodamines 67-76 tetraspanin 7 Rattus norvegicus 185-188 10465451-4 1999 In six cases with injections restricted to the supraoptic nucleus, rhodamine-labelled microspheres were observed in a population of tyrosine hydroxylase-positive neurons located in the A15 cells below the anterior commissure (A15 dorsal) and above the optic chiasm (A15 ventral), and the dorsal and lateral periventricular A14 cell group. Rhodamines 67-76 tetraspanin 7 Rattus norvegicus 226-229 10465451-4 1999 In six cases with injections restricted to the supraoptic nucleus, rhodamine-labelled microspheres were observed in a population of tyrosine hydroxylase-positive neurons located in the A15 cells below the anterior commissure (A15 dorsal) and above the optic chiasm (A15 ventral), and the dorsal and lateral periventricular A14 cell group. Rhodamines 67-76 tetraspanin 7 Rattus norvegicus 226-229 9864175-0 1999 Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833. Rhodamines 10-19 neural cell adhesion molecule 1 Homo sapiens 25-29 9864175-0 1999 Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833. Rhodamines 10-19 ATP binding cassette subfamily B member 1 Homo sapiens 75-89 9864175-2 1999 Efflux of rhodamine from CD56(+) cells was measured before the start of PSC 833 and at varying times thereafter. Rhodamines 10-19 neural cell adhesion molecule 1 Homo sapiens 25-29 9864175-3 1999 Patients receiving PSC 833 had decreased rhodamine efflux from their circulating CD56(+) cells. Rhodamines 41-50 neural cell adhesion molecule 1 Homo sapiens 81-85 9864175-9 1999 We conclude that measurement of rhodamine efflux from CD56(+) cells provides a surrogate assay with the potential for monitoring Pgp antagonism in clinical trials. Rhodamines 32-41 neural cell adhesion molecule 1 Homo sapiens 54-58 9864175-9 1999 We conclude that measurement of rhodamine efflux from CD56(+) cells provides a surrogate assay with the potential for monitoring Pgp antagonism in clinical trials. Rhodamines 32-41 ATP binding cassette subfamily B member 1 Homo sapiens 129-132 9858256-6 1998 The introduction of constitutively active Rac1 resulted in an increase in rhodamine-phalloidin staining, presumably from an accumulation of actin filaments in growth cones, while dominant negative Rac1 caused a decrease in rhodamine-phalloidin staining. Rhodamines 223-232 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Gallus gallus 42-46 9858256-6 1998 The introduction of constitutively active Rac1 resulted in an increase in rhodamine-phalloidin staining, presumably from an accumulation of actin filaments in growth cones, while dominant negative Rac1 caused a decrease in rhodamine-phalloidin staining. Rhodamines 223-232 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Gallus gallus 197-201 9821664-8 1998 These results imply that rhodamine 123 is secreted via P-glycoprotein in renal tubules and that the renal secretory clearance of rhodamine 123 was reduced after acute renal failure, probably because of impairment of P-glycoprotein. Rhodamines 25-34 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 55-69 9818966-8 1998 Identification of compounds showing Pdr1p, Pdr3p-dependent, but Pdr5p-, Snq2p-, and Yor1p-independent toxicity, reflected in the case of rhodamine 6G, by efflux alterations, suggests the involvement of new drug resistance genes and is a first step toward their identification. Rhodamines 137-146 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 64-69 9818966-8 1998 Identification of compounds showing Pdr1p, Pdr3p-dependent, but Pdr5p-, Snq2p-, and Yor1p-independent toxicity, reflected in the case of rhodamine 6G, by efflux alterations, suggests the involvement of new drug resistance genes and is a first step toward their identification. Rhodamines 137-146 ATP-binding cassette transporter SNQ2 Saccharomyces cerevisiae S288C 72-77 9818966-8 1998 Identification of compounds showing Pdr1p, Pdr3p-dependent, but Pdr5p-, Snq2p-, and Yor1p-independent toxicity, reflected in the case of rhodamine 6G, by efflux alterations, suggests the involvement of new drug resistance genes and is a first step toward their identification. Rhodamines 137-146 ATP-binding cassette transporter YOR1 Saccharomyces cerevisiae S288C 84-89 9888602-4 1998 Using phalloidin-rhodamine labeling of actin microfilaments, we observed that VIP and ACTH strongly affect cytoskeletal organization. Rhodamines 17-26 vasoactive intestinal peptide Homo sapiens 78-81 9888602-4 1998 Using phalloidin-rhodamine labeling of actin microfilaments, we observed that VIP and ACTH strongly affect cytoskeletal organization. Rhodamines 17-26 proopiomelanocortin Homo sapiens 86-90 9453629-4 1998 Changes in the fluorescence intensity of rhodamine-phalloidin-labeled F-actin in serial optical sections of single HGF were quantified by confocal microscopy image analysis. Rhodamines 41-50 hepatocyte growth factor Homo sapiens 115-118 9692365-17 1998 Rhodamine-phalloidin staining of the F-actin cytoskeleton showed disruption of the cytoskeleton with radiation exposure, increased density of F-actin filaments with KGF treatment, and resistance to disruption when cells were pretreated with KGF and exposed to radiation. Rhodamines 0-9 fibroblast growth factor 7 Homo sapiens 165-168 9692365-17 1998 Rhodamine-phalloidin staining of the F-actin cytoskeleton showed disruption of the cytoskeleton with radiation exposure, increased density of F-actin filaments with KGF treatment, and resistance to disruption when cells were pretreated with KGF and exposed to radiation. Rhodamines 0-9 fibroblast growth factor 7 Homo sapiens 241-244 9557616-7 1998 In mobilized PB 54% of the CD34+ cells (n=5) were rhodamine dull compared to 22% in steady-state BM (P=0.014) [n=6]. Rhodamines 50-59 CD34 molecule Homo sapiens 27-31 9450972-4 1998 Selected mutant Pdr5 transporters were analyzed with respect to their expression levels, subcellular localization, drug resistance profiles to cycloheximide, rhodamines, antifungal azoles, steroids, and sensitivity to the inhibitor FK506. Rhodamines 158-168 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 16-20 9417083-4 1998 Time-dependent colocalization of beta2AR-GFP with rhodamine-labeled transferrin and rhodamine-labeled dextran following agonist exposure demonstrates receptor distribution to early endosomes (sequestration) and lysosomes (down-regulation), respectively. Rhodamines 50-59 adrenoceptor beta 2 Homo sapiens 33-40 9417083-4 1998 Time-dependent colocalization of beta2AR-GFP with rhodamine-labeled transferrin and rhodamine-labeled dextran following agonist exposure demonstrates receptor distribution to early endosomes (sequestration) and lysosomes (down-regulation), respectively. Rhodamines 50-59 transferrin Homo sapiens 68-79 9744774-9 1998 There was no measurable decline in the fura2 free acid fluorescence in 1 h while the fluorescence due to rhodamine 123 diminished rapidly in cells overexpressing Pgp. Rhodamines 105-114 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 162-165 9890665-6 1998 Activity of plasma membrane Pgp was examined in parental and resistant cells due to rhodamine-accumulation assay. Rhodamines 84-93 phosphoglycolate phosphatase Homo sapiens 28-31 9476146-2 1998 Pgp can be detected in human cancers by immunohistochemistry, RNA probes, or by functional assays utilizing transported fluorescent dyes such as rhodamine. Rhodamines 145-154 phosphoglycolate phosphatase Homo sapiens 0-3 9687882-5 1998 In resistant cells, MDR is characterized by overexpression of P-gp and by the enhanced efflux, and P-gp fluorescence probe, rhodamine 123 (Rh 123). Rhodamines 124-133 ATP binding cassette subfamily B member 1 Homo sapiens 99-103 9464818-6 1997 Using two-color flow cytometry, we observed that FITC-LPS binds to My4-saturated monocytes in association with soluble (s)CD14 present in serum as revealed by staining with rhodamine-labeled My4 mAb. Rhodamines 173-182 CD14 molecule Homo sapiens 122-126 9706741-4 1998 We assessed the ability of myoglobin (Mb) or hemoglobin (Hb) to oxidize dihydrorhodamine (DHR) to rhodamine (RH) in the presence of O2-/H2O2 and/or NO. Rhodamines 79-88 myoglobin Homo sapiens 27-36 9706741-4 1998 We assessed the ability of myoglobin (Mb) or hemoglobin (Hb) to oxidize dihydrorhodamine (DHR) to rhodamine (RH) in the presence of O2-/H2O2 and/or NO. Rhodamines 109-111 myoglobin Homo sapiens 27-36 9436932-3 1997 P-gp expression in the myeloma cells was determined using monoclonal antibody 4E3.16 and the rhodamine 123 functional test. Rhodamines 93-102 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 9311609-9 1997 Rhodamine efflux data, indicated by PGP overexpression, underlined the development of this MDR mechanism in the newly established breast carcinoma lines MT-1/ADR, MT-3/ADR and MaTu/ADR. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 36-39 9397986-2 1997 We tested whether genistein, a modulator of drug resistance in tumor cells, affects biliary secretion of substrates of canalicular multispecific organic anion transporter (cmoat) (glucuronides of bilirubin and rhodamine, glutathione conjugate of bromsulphthalein) and of P-glycoprotein (Pgp) (rhodamine), respectively. Rhodamines 210-219 ATP binding cassette subfamily C member 2 Rattus norvegicus 172-177 9397986-2 1997 We tested whether genistein, a modulator of drug resistance in tumor cells, affects biliary secretion of substrates of canalicular multispecific organic anion transporter (cmoat) (glucuronides of bilirubin and rhodamine, glutathione conjugate of bromsulphthalein) and of P-glycoprotein (Pgp) (rhodamine), respectively. Rhodamines 293-302 ATP binding cassette subfamily C member 2 Rattus norvegicus 119-170 9397986-2 1997 We tested whether genistein, a modulator of drug resistance in tumor cells, affects biliary secretion of substrates of canalicular multispecific organic anion transporter (cmoat) (glucuronides of bilirubin and rhodamine, glutathione conjugate of bromsulphthalein) and of P-glycoprotein (Pgp) (rhodamine), respectively. Rhodamines 293-302 ATP binding cassette subfamily C member 2 Rattus norvegicus 172-177 9310367-0 1997 Efficiency of P-glycoprotein-mediated exclusion of rhodamine dyes from multidrug-resistant cells is determined by their passive transmembrane movement rate. Rhodamines 51-60 ATP binding cassette subfamily B member 1 Homo sapiens 14-28 9393602-4 1997 Pgp status was determined by using monoclonal antibodies JSB-1 and MRK-16 and by assessment of rhodamine efflux. Rhodamines 95-104 ATP binding cassette subfamily B member 1 Homo sapiens 0-3 9310367-2 1997 For this purpose, seven rhodamine dyes were examined for their P-glycoprotein-mediated exclusion from MDR cells, their localization in wild-type drug-sensitive cells, their capacity to stimulate the ATPase activity of P-glycoprotein reconstituted in proteoliposomes, and their transmembrane movement rate in artificial liposomes. Rhodamines 24-33 ATP binding cassette subfamily B member 1 Homo sapiens 218-232 9310367-5 1997 The transmembrane movement rate proved the major factor determining the efficacy of the P-glycoprotein-mediated exclusion of rhodamine dyes from MDR cells. Rhodamines 125-134 ATP binding cassette subfamily B member 1 Homo sapiens 88-102 9322679-5 1997 P-gp activity was defined as a ratio of mean rhodamine 123 accumulation with/without verapamil. Rhodamines 45-54 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 9240371-3 1997 When human serum albumin (HSA) coupled to rhodamine (r) was injected, it initially filled the varicosity; within seconds, however, it began to accumulate in packets and by 15 min was punctate. Rhodamines 13-14 albumin Homo sapiens 26-29 9145916-5 1997 The pattern of TRH receptor immunofluorescence was the same over a wide range of receptor expression in transiently transfected COS7 cells, and all cell lines bound similar amounts of 3H- and rhodamine-labeled TRH analogs, suggesting that cell-specific differences in TRH receptor localization were not simply the result of overexpression. Rhodamines 192-201 thyrotropin releasing hormone Homo sapiens 210-213 9205006-4 1997 We have focused our efforts of P-gp detection on flow cytometry using a dual technique of P-gp staining with antibodies for the extracellular epitope (MRK16) and a functional analysis of P-gp using the rhodamine efflux assay and the effect of P-gp inhibitors such as SDZ PSC 833. Rhodamines 202-211 ATP binding cassette subfamily B member 1 Homo sapiens 31-35 9145916-5 1997 The pattern of TRH receptor immunofluorescence was the same over a wide range of receptor expression in transiently transfected COS7 cells, and all cell lines bound similar amounts of 3H- and rhodamine-labeled TRH analogs, suggesting that cell-specific differences in TRH receptor localization were not simply the result of overexpression. Rhodamines 192-201 thyrotropin releasing hormone Homo sapiens 210-213 9108417-8 1997 Multidrug resistance investigations suggest that agressive clinical findings could be related to MDR1 gene expression as confirmed by MDR1 mRNA detection, MDR1 gene product (Pgp) expression, and a functional multidrug resistance study using rhodamine efflux by flow-cytometry. Rhodamines 241-250 ATP binding cassette subfamily B member 1 Homo sapiens 97-101 9108099-7 1997 However, both mdr1a and mdr1b P-gps contributed to the extrusion of rhodamine from hematopoietic progenitor cells, suggesting a potential role for the endogenous mdr1-type P-gps in protection of bone marrow against cytotoxic anticancer drugs. Rhodamines 68-77 ATP-binding cassette, sub-family B (MDR/TAP), member 1A Mus musculus 14-19 9108099-7 1997 However, both mdr1a and mdr1b P-gps contributed to the extrusion of rhodamine from hematopoietic progenitor cells, suggesting a potential role for the endogenous mdr1-type P-gps in protection of bone marrow against cytotoxic anticancer drugs. Rhodamines 68-77 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 24-29 9108099-7 1997 However, both mdr1a and mdr1b P-gps contributed to the extrusion of rhodamine from hematopoietic progenitor cells, suggesting a potential role for the endogenous mdr1-type P-gps in protection of bone marrow against cytotoxic anticancer drugs. Rhodamines 68-77 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 14-18 9058588-2 1997 In this study, we developed and characterized a new antagonist analogue of cholecystokinin (D-Tyr-Gly-[(Nle28,31,D-Trp30)cholecystokinin-26-32]-phen eth yl ester) that can be tagged with a fluorescent rhodamine and radioiodinated. Rhodamines 201-210 cholecystokinin Homo sapiens 121-136 9050789-4 1997 Using a sheep antibody to a fragment of the third intracellular loop of the 5-HT(1A)R, we localized 5-HT(1A)R immunoreactivity (ir) to IML-projecting neurons that were retrogradely labeled with rhodamine beads injected into the IML of adult male rats. Rhodamines 194-203 5-hydroxytryptamine receptor 1A Rattus norvegicus 76-83 9050789-4 1997 Using a sheep antibody to a fragment of the third intracellular loop of the 5-HT(1A)R, we localized 5-HT(1A)R immunoreactivity (ir) to IML-projecting neurons that were retrogradely labeled with rhodamine beads injected into the IML of adult male rats. Rhodamines 194-203 5-hydroxytryptamine receptor 1A Rattus norvegicus 100-107 9150713-3 1997 The intracellular rhodamine (Rh123) contents also increased in P-gp-positive blasts and K562/ADM cells with MS-209. Rhodamines 18-27 phosphoglycolate phosphatase Homo sapiens 63-67 9058588-2 1997 In this study, we developed and characterized a new antagonist analogue of cholecystokinin (D-Tyr-Gly-[(Nle28,31,D-Trp30)cholecystokinin-26-32]-phen eth yl ester) that can be tagged with a fluorescent rhodamine and radioiodinated. Rhodamines 201-210 cholecystokinin Homo sapiens 75-90 9038218-7 1997 The mutant P-glycoprotein has a decreased affinity for PSC 833 and vinblastine and a decreased ability to transport rhodamine 123. Rhodamines 116-125 ATP binding cassette subfamily B member 1 Homo sapiens 11-25 9588823-10 1997 Treatments of bradykinin and TNF that translocated PKC also showed cytoskeletal rearrangement of rhodamine-phalloidin stained actin, causing it to become more prevalent near cell membranes and concentrated at focal points between cells. Rhodamines 97-106 kininogen 1 Homo sapiens 14-24 9029024-3 1997 Pgp was measured in CD34+ progenitors with a rhodamine efflux assay. Rhodamines 45-54 phosphoglycolate phosphatase Homo sapiens 0-3 9029024-5 1997 Pgp measured by the monoclonal antibody antibody (MoAb) MRK-16 was low in the rhodamine dull, but significantly (P < 0.04) higher than in the rhodamine bright cells. Rhodamines 78-87 phosphoglycolate phosphatase Homo sapiens 0-3 9029024-5 1997 Pgp measured by the monoclonal antibody antibody (MoAb) MRK-16 was low in the rhodamine dull, but significantly (P < 0.04) higher than in the rhodamine bright cells. Rhodamines 145-154 phosphoglycolate phosphatase Homo sapiens 0-3 9588823-10 1997 Treatments of bradykinin and TNF that translocated PKC also showed cytoskeletal rearrangement of rhodamine-phalloidin stained actin, causing it to become more prevalent near cell membranes and concentrated at focal points between cells. Rhodamines 97-106 tumor necrosis factor Homo sapiens 29-32 9588823-10 1997 Treatments of bradykinin and TNF that translocated PKC also showed cytoskeletal rearrangement of rhodamine-phalloidin stained actin, causing it to become more prevalent near cell membranes and concentrated at focal points between cells. Rhodamines 97-106 protein kinase C alpha Homo sapiens 51-54 8968602-0 1996 Fluorescence polarization of skeletal muscle fibers labeled with rhodamine isomers on the myosin heavy chain. Rhodamines 65-74 PBV1SPCR2 Oryctolagus cuniculus 90-108 9013725-8 1997 Codistribution of merlin and F-actin filaments was found in filopodia, ruffling membranes and at the insertion points of stress fibers at cell/substrate adhesion junctions as shown by phalloidin-rhodamine staining. Rhodamines 195-204 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor Homo sapiens 18-24 8977240-9 1996 The ability of Tpo and SCF to synergistically enhance the growth of Lin- Sca-1+ progenitors was predominantly observed in the more primitive rhodamine 123(lo) fraction. Rhodamines 141-150 thrombopoietin Mus musculus 15-18 8977240-9 1996 The ability of Tpo and SCF to synergistically enhance the growth of Lin- Sca-1+ progenitors was predominantly observed in the more primitive rhodamine 123(lo) fraction. Rhodamines 141-150 kit ligand Mus musculus 23-26 8977240-9 1996 The ability of Tpo and SCF to synergistically enhance the growth of Lin- Sca-1+ progenitors was predominantly observed in the more primitive rhodamine 123(lo) fraction. Rhodamines 141-150 ataxin 1 Mus musculus 73-78 8940170-5 1996 Pdr5p extrudes rhodamines 6G and 123, from intact yeast cells in an energy-dependent manner. Rhodamines 15-25 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 0-5 9350197-9 1997 A reliable way to measure Pgp seems to be the assessment of the active transport of fluorescent Pgp substrates, such as rhodamine 123 out of AML cells. Rhodamines 120-129 ATP binding cassette subfamily B member 1 Homo sapiens 26-29 8939917-4 1996 Treatment with TNF and ActD resulted in the loss of 80% of rhodamine fluorescence within 6 h, a time prior to any loss of viability. Rhodamines 59-68 tumor necrosis factor Homo sapiens 15-18 8980395-0 1996 Acceleration of MRP-associated efflux of rhodamine 123 by genistein and related compounds. Rhodamines 41-50 ATP binding cassette subfamily C member 1 Homo sapiens 16-19 8939917-6 1996 Potentiation of the cytotoxicity of TNF by PBzR agonists was associated with induction of the MPT, as assessed by the loss of rhodamine fluorescence. Rhodamines 126-135 tumor necrosis factor Homo sapiens 36-39 8781417-9 1996 In stroma-free cultures, TPO activated a quiescent CD34+Lin-Rhodamine 123lo subset of primitive hematopoietic progenitor cells into cycle, without loss of CD34 expression. Rhodamines 60-69 CD34 molecule Homo sapiens 51-55 8945621-6 1996 The presence of exogenous adenosine (0.5 microM) circumvented AMP-CP-induced inhibition of rhodamine efflux from EL4/ADM cells. Rhodamines 91-100 epilepsy 4 Mus musculus 113-116 8925885-4 1996 N-terminal modification of Tat with rhodamine prevented inhibition of enzymatic activity of DP IV as well as suppression of DNA synthesis of mitogen-stimulated human T cells. Rhodamines 36-45 tyrosine aminotransferase Homo sapiens 27-30 8695847-4 1996 The efflux of Rh123 could be inhibited by verapamil, suggesting that rhodamine efflux from primitive hematopoietic cells is primarily due to the P-glycoprotein (P-gp) pump or another intracellular transport system affected by verapamil. Rhodamines 69-78 ATP binding cassette subfamily B member 1 Homo sapiens 145-159 8695847-4 1996 The efflux of Rh123 could be inhibited by verapamil, suggesting that rhodamine efflux from primitive hematopoietic cells is primarily due to the P-glycoprotein (P-gp) pump or another intracellular transport system affected by verapamil. Rhodamines 69-78 ATP binding cassette subfamily B member 1 Homo sapiens 161-165 8913436-5 1996 Mifepristone, when used at a 10 microM concentration thought to be achievable in vivo without major toxicity, was also able to markedly decrease cellular rhodamine 123 efflux occurring in CD34+ blast cells isolated from six patients suffering from myeloid acute leukemias. Rhodamines 154-163 CD34 molecule Homo sapiens 188-192 8913319-3 1996 However, accumulation of daunorubicin and rhodamine 123 was > 85% reduced in the P-glycoprotein-expressing subline compared to 40-50% in the MRP-expressing subline. Rhodamines 42-51 ATP binding cassette subfamily B member 1 Homo sapiens 84-98 8650203-5 1996 Most importantly, reserpine and doxorubicin completely abolish Mdr1-mediated rhodamine resistance. Rhodamines 77-86 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 63-67 8624264-8 1996 Staurosporine and CGP 41251 at 10 and 20 nM, respectively, decreased efflux of the P-gp probe rhodamine 123 (R123) from MCF-7/Adr cells, whereas RO 31 8220 and GF 109203X at 640 nM were inactive. Rhodamines 94-103 ATP binding cassette subfamily B member 1 Homo sapiens 83-87 8605330-4 1996 The most purified rhodamine-bright bone marrow subset contains 80% cells that respond to calcium ionophore by increased HDC mRNA expression. Rhodamines 18-27 histidine decarboxylase Mus musculus 120-123 8605969-8 1996 In contrast, a high percentage of the Sca-1+Lin*- cells isolated from 14.5-day-old FL stained with the AA4.1, anti-Mac-1, and the anti-CD45RB mAbs and retained Rhodamine 123 (Rh123(bright)), whereas the Sca-1+Lin-WGA+ CRU-containing fraction of adult BM cells was found to be AA4.1-, Mac-1-, CD45RB-, and Rh123(dull). Rhodamines 160-169 lymphocyte antigen 6 complex, locus A Mus musculus 38-43 9350197-9 1997 A reliable way to measure Pgp seems to be the assessment of the active transport of fluorescent Pgp substrates, such as rhodamine 123 out of AML cells. Rhodamines 120-129 ATP binding cassette subfamily B member 1 Homo sapiens 96-99 8695847-2 1996 Heterogeneous rhodamine staining is seen within the CD34+ population, and the staining patterns differ dramatically between fetal BM (FBM), adult BM (ABM) and mobilized peripheral blood (MPB). Rhodamines 14-23 CD34 molecule Homo sapiens 52-56 8837723-12 1996 To demonstrate that both the antibody and drug localized in the same group of prostatic epithelial cells, we used an immunoconjugate in which the PSA-IgG was labeled with rhodamine and 5"-Fu-2"-d-5"-amp with FITC. Rhodamines 171-180 aminopeptidase puromycin sensitive Homo sapiens 146-149 8757962-5 1996 Anti-ICAM-1 pretreatment inhibited the increase in ICAM-1 expression and the decrease in rhodamine 123 fluorescence on AH70 cells after co-culture with KC. Rhodamines 89-98 intercellular adhesion molecule 1 Rattus norvegicus 5-11 8766007-10 1996 A third parameter influencing the interaction with the choline+ transporter is the presence of two amino groups with high pKa values or one amino group and a permanent positive charge, as is documented with the two-ring aminostyryl and rhodamine compounds, as well as three-ring aminoacridine, aminophenanthrene and cyanine compounds. Rhodamines 236-245 solute carrier family 6 member 8 Rattus norvegicus 55-75 8925885-4 1996 N-terminal modification of Tat with rhodamine prevented inhibition of enzymatic activity of DP IV as well as suppression of DNA synthesis of mitogen-stimulated human T cells. Rhodamines 36-45 dipeptidyl peptidase 4 Homo sapiens 92-97 8616825-7 1996 Moreover we could correlate MDR1 gene expression and modulation of rhodamine 123 efflux from the leukaemic blasts by proven P-gp MDR chemosensitizing agents such as SDZ PSC 833, dexverapamil and dexniguldipine. Rhodamines 67-76 phosphoglycolate phosphatase Homo sapiens 124-128 8668925-3 1996 Rhodamine 123 dye efflux measures P-glycoprotein activity and inhibition of P-glycoprotein results in dye retention. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 34-48 8668925-3 1996 Rhodamine 123 dye efflux measures P-glycoprotein activity and inhibition of P-glycoprotein results in dye retention. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 76-90 8562416-4 1996 Pgp functional activity was investigated by evaluation of verapamil influence upon rhodamine 123 efflux from the cells. Rhodamines 83-92 ATP binding cassette subfamily B member 1 Homo sapiens 0-3 8872748-3 1996 The active enzymes on the cell surfaces in frozen sections of human colonic carcinoma tissue were located by staining with two active site directed fluorescent inhibitors, 9-aminoacridine (9-AA) and Rhodamine labelled PAI-1 (Rh-PAI-1), followed by fluorescence microscopy. Rhodamines 199-208 serpin family E member 1 Homo sapiens 218-223 7587721-0 1995 Flow cytometric determination of aminopeptidase activities in viable cells using fluorogenic rhodamine 110 substrates. Rhodamines 93-102 carboxypeptidase Q Homo sapiens 33-47 7564516-3 1995 P-gp function was measured by rhodamine 123 (Rh 123) efflux kinetics. Rhodamines 30-39 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 7669666-1 1995 The MDR1 gene product P-glycoprotein (P-gp) extrudes several anticancer drugs including taxol and fluorescent dyes such as rhodamine (Rh123). Rhodamines 123-132 ATP binding cassette subfamily B member 1 Homo sapiens 4-8 7669666-1 1995 The MDR1 gene product P-glycoprotein (P-gp) extrudes several anticancer drugs including taxol and fluorescent dyes such as rhodamine (Rh123). Rhodamines 123-132 ATP binding cassette subfamily B member 1 Homo sapiens 22-36 7669666-1 1995 The MDR1 gene product P-glycoprotein (P-gp) extrudes several anticancer drugs including taxol and fluorescent dyes such as rhodamine (Rh123). Rhodamines 123-132 ATP binding cassette subfamily B member 1 Homo sapiens 38-42 8522584-7 1995 Scanning electron microscopy and rhodamine-phalloidin staining indicates that the myosin I double mutants appear to extend a larger number of actin-filled structures, such as filopodia and crowns, than wild-type cells. Rhodamines 33-42 myosin heavy chain 14 Homo sapiens 82-88 8522588-2 1995 To characterize the regions of CP190 responsible for its dynamic behavior, we injected rhodamine-labeled fusion proteins spanning most of CP190 into early Drosophila embryos, where their localizations were characterized using time-lapse fluorescence confocal microscopy. Rhodamines 87-96 Centrosomal protein 190kD Drosophila melanogaster 31-36 8586652-3 1995 These results indicate that nebulin inhibits rhodamine-phalloidin binding to actin and suggests that the unidirectional rhodamine-phalloidin binding may be due to cooperative competitive binding, i.e. phalloidin "unzips" nebulin starting from the pointed ends of the thin filaments. Rhodamines 45-54 nebulin Homo sapiens 28-35 7677179-9 1995 Dual labeling experiments using biotinylated fibrinogen and FITC-streptavidin as well as a monoclonal anti-GPIIIa antibody labeled with rhodamine-conjugated anti-mouse IgG demonstrated the co-localization of fibrinogen and GPIIIa. Rhodamines 136-145 integrin subunit beta 3 Homo sapiens 107-113 7677179-9 1995 Dual labeling experiments using biotinylated fibrinogen and FITC-streptavidin as well as a monoclonal anti-GPIIIa antibody labeled with rhodamine-conjugated anti-mouse IgG demonstrated the co-localization of fibrinogen and GPIIIa. Rhodamines 136-145 fibrinogen beta chain Homo sapiens 208-218 7677179-9 1995 Dual labeling experiments using biotinylated fibrinogen and FITC-streptavidin as well as a monoclonal anti-GPIIIa antibody labeled with rhodamine-conjugated anti-mouse IgG demonstrated the co-localization of fibrinogen and GPIIIa. Rhodamines 136-145 integrin subunit beta 3 Homo sapiens 223-229 7795216-10 1995 P-glycoprotein function in host marrow was confirmed by rhodamine-123 efflux. Rhodamines 56-65 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 7477881-6 1995 In further experiments, rhodamine-conjugated latex microspheres were injected into the supraoptic nucleus to retrogradely label afferent neurons, and the brains were processed with double-immunohistochemistry for tyrosine hydroxylase and Fos-like protein. Rhodamines 24-33 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 238-241 7552989-6 1995 Rhodamine efflux studies showed that this additional p-glycoprotein was functional and that the frequency of cells with high p-glycoprotein levels was higher in the transduced cells than in the non-transduced cells. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 53-67 7552989-6 1995 Rhodamine efflux studies showed that this additional p-glycoprotein was functional and that the frequency of cells with high p-glycoprotein levels was higher in the transduced cells than in the non-transduced cells. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 125-139 7643452-2 1995 Functional P-gp expression was examined by Rhodamine-123 efflux test, and estimated with the data by RT-PCR method. Rhodamines 43-52 ATP binding cassette subfamily B member 1 Homo sapiens 11-15 7559918-7 1995 In contrast, CsA and PSC were more potent as inhibitors of P-gp-mediated rhodamine 123 dye efflux than the verapamil isomers. Rhodamines 73-82 ATP binding cassette subfamily B member 1 Homo sapiens 59-63 7473775-5 1995 Fibroblasts, visualized after staining with rhodamine-labeled alpha 2-macroglobulin, were only rarely detected. Rhodamines 44-53 alpha-2-macroglobulin Rattus norvegicus 62-83 7507731-10 1994 Flow cytometric analysis of rhodamine 123 dye efflux indicated a functional P-gp that was efficiently blocked by verapamil or cyclosporin A (CsA). Rhodamines 28-37 phosphoglycolate phosphatase Homo sapiens 76-80 7787113-1 1995 Structural changes of the myosin heads were correlated with mechanical events in the cross-bridge cycle by measuring fluorescence polarization signals at high time resolution from rhodamine probes bound to myosin regulatory light chains in skeletal muscle fibers. Rhodamines 180-189 myosin heavy chain 14 Homo sapiens 26-32 7787113-1 1995 Structural changes of the myosin heads were correlated with mechanical events in the cross-bridge cycle by measuring fluorescence polarization signals at high time resolution from rhodamine probes bound to myosin regulatory light chains in skeletal muscle fibers. Rhodamines 180-189 myosin heavy chain 14 Homo sapiens 206-212 7895783-6 1995 IgE and IL-3 responder cells also cannot be distinguished on the basis of size, internal structure, and rhodamine (Rh) retention. Rhodamines 115-117 interleukin 3 Mus musculus 8-12 7831321-1 1995 Endocytosis and recycling of both thyrotropin-releasing hormone (TRH) and its G-protein-coupled receptor were visualized by conventional and confocal fluorescence microscopy in pituitary cells using a rhodamine-labeled TRH analog (Rhod-TRH) and indirect immunofluorescent staining of cells stably transfected with an epitope-tagged TRH receptor (TRHR). Rhodamines 201-210 thyrotropin releasing hormone Homo sapiens 34-63 7831321-1 1995 Endocytosis and recycling of both thyrotropin-releasing hormone (TRH) and its G-protein-coupled receptor were visualized by conventional and confocal fluorescence microscopy in pituitary cells using a rhodamine-labeled TRH analog (Rhod-TRH) and indirect immunofluorescent staining of cells stably transfected with an epitope-tagged TRH receptor (TRHR). Rhodamines 201-210 thyrotropin releasing hormone Homo sapiens 65-68 7831321-1 1995 Endocytosis and recycling of both thyrotropin-releasing hormone (TRH) and its G-protein-coupled receptor were visualized by conventional and confocal fluorescence microscopy in pituitary cells using a rhodamine-labeled TRH analog (Rhod-TRH) and indirect immunofluorescent staining of cells stably transfected with an epitope-tagged TRH receptor (TRHR). Rhodamines 201-210 thyrotropin releasing hormone Homo sapiens 219-222 7831321-1 1995 Endocytosis and recycling of both thyrotropin-releasing hormone (TRH) and its G-protein-coupled receptor were visualized by conventional and confocal fluorescence microscopy in pituitary cells using a rhodamine-labeled TRH analog (Rhod-TRH) and indirect immunofluorescent staining of cells stably transfected with an epitope-tagged TRH receptor (TRHR). Rhodamines 201-210 thyrotropin releasing hormone Homo sapiens 219-222 7850770-6 1995 GC3/c1 cells after carbonyl cyanide-m-chlorophenylhydrazone rapidly lost rhodamine 123 fluorescence from mitochondria; after 1 mM sulofenur, fluorescence faded slowly. Rhodamines 73-82 ankyrin repeat domain 36 Mus musculus 0-3 7733620-0 1995 Rhodamine 123: is it an appropriate dye to study P-glycoprotein activity in adriamycin-resistant K562 cells? Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 49-63 7733620-5 1995 Thus, in adriamycin-resistant K562 cells, the rhodamine efflux may be due to P-glycoprotein activity and also to a nonspecific targeting of dye in resistant K562 cells. Rhodamines 46-55 ATP binding cassette subfamily B member 1 Homo sapiens 77-91 7553917-10 1995 PtK2 cells transfected with this RSV vector for 2-3 days showed disassembly of stress fibers as detected by rhodamine-phalloidin staining; in these cells the membrane actin was also greatly diminished or absent and the border of the cells was markedly retracted. Rhodamines 108-117 protein tyrosine kinase 2 Homo sapiens 0-4 7727866-6 1994 The detection of functional GP170 can be identified by rhodamine or daunorubicin intracellular accumulation with flux cytometry or by scintigraphically imaging GP170 expression in vivo with Tc-Sestamibi. Rhodamines 55-64 ATP binding cassette subfamily B member 1 Homo sapiens 28-33 7865127-3 1994 Rhodamine retrograde-prelabelled DA neurons were cultured on a Phastgel containing all the electrophoretically separated protein bands from CPe, and able to fish out from it their own trophic factor, a 12.5-kD protein band. Rhodamines 0-9 carboxypeptidase E Rattus norvegicus 140-143 7980629-4 1994 P-glycoprotein was functional in terms of rhodamine dye excretion and its susceptibility to the MDR-reversing agents. Rhodamines 42-51 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 7513198-8 1994 P-gly function was determined for each lineage using dual-labeling for lineage and P-gly substrate (rhodamine 123). Rhodamines 100-109 ATP binding cassette subfamily B member 1 Homo sapiens 0-5 7513198-8 1994 P-gly function was determined for each lineage using dual-labeling for lineage and P-gly substrate (rhodamine 123). Rhodamines 100-109 ATP binding cassette subfamily B member 1 Homo sapiens 83-88 7513198-13 1994 We conclude that (1) P-gly and the MDR1 mRNA are expressed in normal leukocytes, (2) this P-gly expression is lineage specific with relatively high levels among CD56+ cells, and (3) the expression of P-gly in granulocytes is not associated with transport of the P-gly substrate, rhodamine 123, out of the cell. Rhodamines 279-288 ATP binding cassette subfamily B member 1 Homo sapiens 21-26 7513198-13 1994 We conclude that (1) P-gly and the MDR1 mRNA are expressed in normal leukocytes, (2) this P-gly expression is lineage specific with relatively high levels among CD56+ cells, and (3) the expression of P-gly in granulocytes is not associated with transport of the P-gly substrate, rhodamine 123, out of the cell. Rhodamines 279-288 ATP binding cassette subfamily B member 1 Homo sapiens 35-39 7513198-13 1994 We conclude that (1) P-gly and the MDR1 mRNA are expressed in normal leukocytes, (2) this P-gly expression is lineage specific with relatively high levels among CD56+ cells, and (3) the expression of P-gly in granulocytes is not associated with transport of the P-gly substrate, rhodamine 123, out of the cell. Rhodamines 279-288 ATP binding cassette subfamily B member 1 Homo sapiens 90-95 7513198-13 1994 We conclude that (1) P-gly and the MDR1 mRNA are expressed in normal leukocytes, (2) this P-gly expression is lineage specific with relatively high levels among CD56+ cells, and (3) the expression of P-gly in granulocytes is not associated with transport of the P-gly substrate, rhodamine 123, out of the cell. Rhodamines 279-288 ATP binding cassette subfamily B member 1 Homo sapiens 90-95 7513198-13 1994 We conclude that (1) P-gly and the MDR1 mRNA are expressed in normal leukocytes, (2) this P-gly expression is lineage specific with relatively high levels among CD56+ cells, and (3) the expression of P-gly in granulocytes is not associated with transport of the P-gly substrate, rhodamine 123, out of the cell. Rhodamines 279-288 ATP binding cassette subfamily B member 1 Homo sapiens 90-95 7929637-5 1994 Rhodamine-labeled Fab fragments against a cytoplasmic epitope of ts-O45-G (rh-P5D4-Fabs) were microinjected into cells to visualize the intracellular viral membrane protein and to determine its mobility by FRAP with a confocal microscope. Rhodamines 0-9 FA complementation group B Homo sapiens 18-21 7912496-0 1994 Inhibition of rhodamine 123 secretion by cyclosporin A as a model of P-glycoprotein mediated transport in liver. Rhodamines 14-23 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 69-83 7912496-4 1994 Both cyclosporin A and rhodamine inhibited photoaffinity labeling of immunoprecipitated P-glycoprotein with azidopine, indicating binding to hepatic P-glycoprotein. Rhodamines 23-32 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 88-102 7912496-4 1994 Both cyclosporin A and rhodamine inhibited photoaffinity labeling of immunoprecipitated P-glycoprotein with azidopine, indicating binding to hepatic P-glycoprotein. Rhodamines 23-32 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 149-163 7508469-3 1994 Out of six tested alkaline phosphatase activity-revealing methods, only the reaction product obtained with the Becton Dickinson CAS Red kit showed an intense red fluorescence with a rhodamine filter set and no signal with epi-polarization illumination. Rhodamines 182-191 BCAR1 scaffold protein, Cas family member Homo sapiens 128-131 8527682-5 1995 The system is tested on rhodamine-alpha-bungarotoxin-labeled acetylcholine receptors (AChRs) on myotubes grown in primary cultures of embryonic rat muscle, in both endogenously clustered and nonclustered regions of AChR distribution. Rhodamines 24-33 cholinergic receptor nicotinic alpha 2 subunit Rattus norvegicus 86-90 7540097-6 1995 To examine direct effects of PAF antagonists on toxin A in T-84 epithelial cell monolayers, rhodamine-labeled phalloidin stained F-actin demonstrated significant disruption of F-actin by toxin A that was reduced by the PAF antagonist BN 52021 or WEB 2170. Rhodamines 92-101 PCNA clamp associated factor Homo sapiens 219-222 7872688-7 1994 It was concluded that MRK16 and rhodamine 123 were well adapted to detect P-gp and evaluate its functional ability. Rhodamines 32-41 ATP binding cassette subfamily B member 1 Homo sapiens 74-78 7969041-0 1994 Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 34-48 7969041-4 1994 There was a significant correlation between mdr-1 expression and rhodamine efflux in the 58 cell lines (r = 0.788, p = 0.0001). Rhodamines 65-74 ATP binding cassette subfamily B member 1 Homo sapiens 44-49 7847840-5 1994 This indicates that the rhodamine efflux is a more function-related marker for MDR than the mdr1 gene and the pgp. Rhodamines 24-33 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 92-96 7847840-5 1994 This indicates that the rhodamine efflux is a more function-related marker for MDR than the mdr1 gene and the pgp. Rhodamines 24-33 phosphoglycolate phosphatase Mus musculus 110-113 8041795-4 1994 Fos-(118-211) and Jun-(225-334) polypeptides were labeled with either 5-iodoacetamidofluorescein or rhodamine X iodoacetamide on unique cysteine residues located in their DNA binding domains. Rhodamines 100-109 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 0-3 8195695-6 1994 FACS analysis of rhodamine-phalloidin-stained MDMs showed that after incubation with IL-1 beta, but not TNF-alpha, the content of F-actin declined in MDMs, coinciding with inhibition of particle phagocytosis. Rhodamines 17-26 interleukin 1 beta Homo sapiens 85-94 7910786-4 1994 P-gp-mediated rhodamine 123 efflux from dye-loaded single-cell suspensions of HCT-8 cells as measured by flow cytometry was not impeded at pHo 6.8 in comparison with pHo 7.5 in standard medium, but at low pHo the inhibitory activity of R-VPL (29% vs 60% rhodamine 123 efflux inhibition) was diminished significantly, again without a reduction in the effect of PSC 833 (rhodamine 123 flux inhibition, 75%). Rhodamines 14-23 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 7910786-4 1994 P-gp-mediated rhodamine 123 efflux from dye-loaded single-cell suspensions of HCT-8 cells as measured by flow cytometry was not impeded at pHo 6.8 in comparison with pHo 7.5 in standard medium, but at low pHo the inhibitory activity of R-VPL (29% vs 60% rhodamine 123 efflux inhibition) was diminished significantly, again without a reduction in the effect of PSC 833 (rhodamine 123 flux inhibition, 75%). Rhodamines 254-263 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 7910786-4 1994 P-gp-mediated rhodamine 123 efflux from dye-loaded single-cell suspensions of HCT-8 cells as measured by flow cytometry was not impeded at pHo 6.8 in comparison with pHo 7.5 in standard medium, but at low pHo the inhibitory activity of R-VPL (29% vs 60% rhodamine 123 efflux inhibition) was diminished significantly, again without a reduction in the effect of PSC 833 (rhodamine 123 flux inhibition, 75%). Rhodamines 254-263 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 8443378-4 1993 Starting from these findings, we further characterized the immature hematopoietic compartment responsible for IL-3-induced histamine synthesis using fluorescence-activated cell sorter (FACS) sorting based on rhodamine retention or wheat germ agglutinin (WGA) affinity. Rhodamines 208-217 interleukin 3 Mus musculus 110-114 7912496-5 1994 Our results indicate that monitoring the biliary rhodamine 123 secretion in the isolated perfused liver of TR- rats offers a new system for testing modulators of P-glycoprotein like cyclosporin A. Rhodamines 49-58 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 162-176 8105101-12 1993 MDR1 mRNA expression was significantly correlated with rhodamine 123 efflux, whereas MDR3 mRNA expression was not significantly correlated; MDR1 and MDR3 mRNA expression was not significantly associated with Rai stage, prior treatment, or disease progresssion. Rhodamines 55-64 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 8271312-6 1993 Indeed, after incubation of oligodendrocytes with C6-NBD-ceramide and rhodamine-labeled transferrin both fluorescent labels colocalized in the Golgi system of the cell body as well as in the structures in the processes. Rhodamines 70-79 transferrin Rattus norvegicus 88-99 8302775-7 1993 Melanophores with either aggregated or dispersed melanosomes had low intensity rhodamine-phalloidin staining of actin filaments compared to nonpigmented cells, whereas the FITC anti-tubulin intensities were comparable in magnitude to that seen in nonpigmented cells. Rhodamines 79-88 actin like 6A S homeolog Xenopus laevis 112-117 7905358-0 1993 Assessment of P-glycoprotein-dependent drug transport in isolated rat hepatocytes using rhodamine 123. Rhodamines 88-97 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 14-28 7691328-5 1993 The quiescent rhodamine 123 dull stem cell fraction was found to express the interleukin 3 (IL-3) receptor beta unit and c-kit, but not the granulocyte-macrophage colony stimulating factor (GM-CSF) receptor beta unit nor flk-2. Rhodamines 14-23 KIT proto-oncogene, receptor tyrosine kinase Homo sapiens 121-126 7691328-9 1993 The SCF-binding cells were found to be all rhodamine 123 bright. Rhodamines 43-52 KIT ligand Homo sapiens 4-7 7694687-2 1993 The results of MDR1 mRNA expression by reverse transcriptase polymerase chain reaction were confirmed by immunostaining using the anti-P-glycoprotein monoclonal antibody UIC2 and by a functional study using the rhodamine efflux test. Rhodamines 211-220 ATP binding cassette subfamily B member 1 Homo sapiens 15-19 7693598-8 1993 When each anti-CTB IgA was mixed with 10 nM CT and applied to the apical surfaces of T84 cell monolayers, all three IgAs blocked CT-induced Cl- secretion in a dose-dependent manner and completely inhibited binding of rhodamine-labelled CT to apical cell membranes. Rhodamines 217-226 CD79a molecule Homo sapiens 19-22 8218101-13 1993 Direct measurement of prothrombinase complex assembly was demonstrated by using an energy transfer phenomenon between fluorescein-labeled factor Va and rhodamine-labeled factor Xa. Rhodamines 152-161 coagulation factor X Homo sapiens 22-36 8105110-11 1993 A verapamil-sensitive drug efflux has been demonstrated for the PC-3 and Du-145, but not for the LNCaP, cell lines, using flow cytometric measurements of the P-gp substrate rhodamine 123 efflux from preloaded cells. Rhodamines 173-182 proprotein convertase subtilisin/kexin type 1 Homo sapiens 64-68 8105110-11 1993 A verapamil-sensitive drug efflux has been demonstrated for the PC-3 and Du-145, but not for the LNCaP, cell lines, using flow cytometric measurements of the P-gp substrate rhodamine 123 efflux from preloaded cells. Rhodamines 173-182 ATP binding cassette subfamily B member 1 Homo sapiens 158-162 7690250-5 1993 Impaired transport of rhodamine in normal T lymphocytes treated with staurosporine demonstrates that modulation of P-glycoprotein function is not limited to cells selected for drug resistance in vitro. Rhodamines 22-31 ATP binding cassette subfamily B member 1 Homo sapiens 115-129 8214031-3 1993 In IMCD3, 5 min of stimulation by 2.5-250 nM AVP significantly depolymerized F-actin by 13-24% in whole cell assays employing the rhodamine-phalloidin binding technique. Rhodamines 130-139 arginine vasopressin Rattus norvegicus 45-48 8220067-3 1993 With biotin-streptavidin-rhodamine, myosin was mainly found at the bile canaliculi level, however with confocal microscopy, the plasma membrane fluorescent staining was more apparent. Rhodamines 25-34 myosin heavy chain 14 Homo sapiens 36-42 7683034-4 1993 Thy-1+ CD34+ cells were further characterized as CD38lo/CD45RO+/CD45RA-/CD71lo/c-kit(lo) and rhodamine 123dull. Rhodamines 93-102 Thy-1 cell surface antigen Homo sapiens 0-5 8384932-1 1993 The localization of topoisomerase II (topo II) in vivo was studied by recording time-lapse, three-dimensional data sets of living Drosophila melanogaster embryos injected with rhodamine-labeled topo II. Rhodamines 176-185 Topoisomerase 2 Drosophila melanogaster 20-36 8384932-1 1993 The localization of topoisomerase II (topo II) in vivo was studied by recording time-lapse, three-dimensional data sets of living Drosophila melanogaster embryos injected with rhodamine-labeled topo II. Rhodamines 176-185 Topoisomerase 2 Drosophila melanogaster 38-45 8384932-1 1993 The localization of topoisomerase II (topo II) in vivo was studied by recording time-lapse, three-dimensional data sets of living Drosophila melanogaster embryos injected with rhodamine-labeled topo II. Rhodamines 176-185 Topoisomerase 2 Drosophila melanogaster 194-201 7680244-2 1993 In this study, expression of multidrug resistance P-glycoprotein on peripheral blood mononuclear cells (PBMC) of 11 patients with GLPD was examined by staining with MRK 16, a monoclonal antibody that binds to an external epitope of P-glycoprotein, and with the dye rhodamine, a known substance to be excreted from the cells through P-glycoprotein. Rhodamines 265-274 ATP binding cassette subfamily B member 1 Homo sapiens 50-64 8432559-5 1993 Cathepsin B/L activity was measured flow cytometrically in single viable cells by the intracellular cleavage of non-fluorescent (Z-Phe-Arg)2-rhodamine 110 to the green fluorescent monoamide Z-Phe-Arg-rhodamine 110 and rhodamine 110. Rhodamines 141-150 cathepsin B Rattus norvegicus 0-11 8329592-2 1993 In this system, distances obtained from A-mode ultrasound will be used to compensate for decreases in fluorescence intensity due to the detector-sample separation distance r. For concentrated rhodamine, a fluorescent dye, compensation has been experimentally achieved assuming fluorescence is emitted isotropically and decreases as 1/r2. Rhodamines 192-201 prostaglandin D2 receptor Homo sapiens 329-333 1571946-12 1992 The effects of quenching of the fluorescent signal by the excitation beam were minimized in the following manner: a) Rhodamine anti-GFAP was substituted for more labile fluoresceine. Rhodamines 117-126 glial fibrillary acidic protein Homo sapiens 132-136 7682495-5 1993 CD5+ B cells were identified by double immunofluorescence staining with rhodamine-conjugated rabbit anti-human immunoglobulin and with a mouse anti-CD5 monoclonal antibody revealed by a fluorescein-conjugated goat anti-mouse immunoglobulin. Rhodamines 72-81 CD5 molecule Homo sapiens 0-3 1515071-0 1992 Membrane permeable fluorogenic rhodamine substrates for selective determination of cathepsin L. Rhodamines 31-40 cathepsin L Homo sapiens 83-94 1476678-14 1992 This colocalization confirms the association of rhodamine-tagged species with F-actin. Rhodamines 48-57 actin, beta Gallus gallus 80-85 1351678-8 1992 Since Thy-1 could be directly labeled with rhodamine, the effect of the size of the labeling ligand on the mobility obtained by the FRAP technique could be explored. Rhodamines 43-52 thymus cell antigen 1, theta Mus musculus 6-11 1599404-7 1992 The rhodamine label in bile was chloroform-soluble, but not identical to the native molecule, and was resistant to phospholipase A2 and alkaline hydrolysis. Rhodamines 4-13 phospholipase A2 group IB Rattus norvegicus 115-131 1639847-8 1992 Double labeling of yeast cells with affinity-purified anti-calmodulin antibody and rhodamine-conjugated phalloidin indicates that calmodulin and actin concentrate in overlapping regions during the cell cycle. Rhodamines 83-92 calmodulin Saccharomyces cerevisiae S288C 130-140 1377237-4 1992 One construct consisted of the nuclear import signal peptide (sp) of the SV40 large T antigen, coupled to human serum albumin (HSA) and rhodamine (r). Rhodamines 9-10 CD24 molecule Rattus norvegicus 127-130 1607935-3 1992 The overall staining pattern or intensity was minimally altered after stimulation, although dopamine-beta-hydroxylase (DBH) antigen, a marker for the chromaffin granule membrane, was exposed preferentially on the plasma membrane areas with lower intensity of rhodamine-phalloidin staining. Rhodamines 259-268 dopamine beta-hydroxylase Homo sapiens 92-117 1607935-3 1992 The overall staining pattern or intensity was minimally altered after stimulation, although dopamine-beta-hydroxylase (DBH) antigen, a marker for the chromaffin granule membrane, was exposed preferentially on the plasma membrane areas with lower intensity of rhodamine-phalloidin staining. Rhodamines 259-268 dopamine beta-hydroxylase Homo sapiens 119-122 1345903-1 1992 Rhodamine-labeled vinculin microinjected into chicken embryo fibroblasts and rhodamine-labeled alpha 2-macroglobulin added to the fibroblast culture medium were sequestered in endocytotic vesicles and digested. Rhodamines 0-9 vinculin Gallus gallus 18-26 1345903-1 1992 Rhodamine-labeled vinculin microinjected into chicken embryo fibroblasts and rhodamine-labeled alpha 2-macroglobulin added to the fibroblast culture medium were sequestered in endocytotic vesicles and digested. Rhodamines 77-86 vinculin Gallus gallus 18-26 1345903-1 1992 Rhodamine-labeled vinculin microinjected into chicken embryo fibroblasts and rhodamine-labeled alpha 2-macroglobulin added to the fibroblast culture medium were sequestered in endocytotic vesicles and digested. Rhodamines 77-86 alpha-2-macroglobulin Gallus gallus 95-116 1345903-2 1992 When a sealed microcapillary coated with fibronectin or polylysine was attached to the fibroblasts and pulled at speeds of 100-200 microns/h, stretching the plasma membrane, a variable fraction of the endosomes released the rhodamine label. Rhodamines 224-233 fibronectin 1 Gallus gallus 41-52 1665427-6 1991 In contrast, priming with InsP6, with or without FMLP stimulation, results in a sustained assembly of F-actin as visualized with a rhodamine-phalloidin staining technique. Rhodamines 131-140 formyl peptide receptor 1 Homo sapiens 49-53 1661732-5 1991 Coverslips coated with gelsolin, a multi-domain, calcium-dependent capping and severing protein, bound rhodamine-phalloidin-saturated filaments along their length in the presence of EGTA. Rhodamines 103-112 Gelsolin Drosophila melanogaster 23-31 2050110-6 1991 Fluorescence experiments with rhodamine-conjugated Tat show punctate staining on the cell surface and then localization to the cytoplasm and nucleus. Rhodamines 30-39 tyrosine aminotransferase Homo sapiens 51-54 1717068-7 1991 About 20% of the Lin(lineage)-c-kit+ cells were rhodamine-123low and this fraction contained more day-12 CFU-S than day-8 CFU-S. On the basis of these findings, murine hematopoietic stem cells were enriched with normal bone marrow cells. Rhodamines 48-57 KIT proto-oncogene receptor tyrosine kinase Mus musculus 30-35 2070071-4 1991 These procedures have allowed us to ascribe the following features to the cells mainly responsible for IL-3-induced IL-6 production: (1) they possess a low density and a relatively high forward and perpendicular light scatter (FLS/PLS); (2) they are characterized by a high rhodamine (Rh) retention; and (3) their enrichment in various subpopulations is similar to that obtained for progenitors forming colonies in the methylcellulose assay colony-forming units (CFU-C). Rhodamines 274-283 interleukin 3 Mus musculus 103-107 2070071-4 1991 These procedures have allowed us to ascribe the following features to the cells mainly responsible for IL-3-induced IL-6 production: (1) they possess a low density and a relatively high forward and perpendicular light scatter (FLS/PLS); (2) they are characterized by a high rhodamine (Rh) retention; and (3) their enrichment in various subpopulations is similar to that obtained for progenitors forming colonies in the methylcellulose assay colony-forming units (CFU-C). Rhodamines 274-283 interleukin 6 Mus musculus 116-120 2070071-4 1991 These procedures have allowed us to ascribe the following features to the cells mainly responsible for IL-3-induced IL-6 production: (1) they possess a low density and a relatively high forward and perpendicular light scatter (FLS/PLS); (2) they are characterized by a high rhodamine (Rh) retention; and (3) their enrichment in various subpopulations is similar to that obtained for progenitors forming colonies in the methylcellulose assay colony-forming units (CFU-C). Rhodamines 285-287 interleukin 3 Mus musculus 103-107 2070071-4 1991 These procedures have allowed us to ascribe the following features to the cells mainly responsible for IL-3-induced IL-6 production: (1) they possess a low density and a relatively high forward and perpendicular light scatter (FLS/PLS); (2) they are characterized by a high rhodamine (Rh) retention; and (3) their enrichment in various subpopulations is similar to that obtained for progenitors forming colonies in the methylcellulose assay colony-forming units (CFU-C). Rhodamines 285-287 interleukin 6 Mus musculus 116-120 1848561-11 1991 Visualization of microfilaments with rhodamine-conjugated phalloidin showed that PTH altered the cytoskeleton by decreasing the number of stress fibers. Rhodamines 37-46 parathyroid hormone Homo sapiens 81-84 1713528-2 1991 However, about one half of these GnRH neurons also project to fenestrated capillaries as evidenced by uptake and retrograde transport of both peripherally injected Fluoro-Gold and centrally injected rhodamine labeled microspheres. Rhodamines 199-208 gonadotropin releasing hormone 1 Rattus norvegicus 33-37 1987663-7 1991 Additional studies, in which rhodamine-coupled phalloidin was used to visualize F-actin, showed that Cd2+ altered the structure of actin filaments in the cells; there was a significant reduction in the amount of junction-associated F-actin and in the number of stress fibers. Rhodamines 29-38 CD2 molecule Sus scrofa 101-104 34556207-3 2021 Herein, by taking advantage of frequency upconversion luminescence (FUCL) technology, we reported an FUCL probe (NRh-NDs) that can detect GST based on a rhodamine derivative structure decorated with a 2,4-dinitrobenzenesulfonyl group (NDs). Rhodamines 153-162 glutathione S-transferase kappa 1 Homo sapiens 138-141 2144348-3 1990 The rhodamine-labeled fluorescent vasopressin analog, R-MLVP, initially bound in a diffuse manner at the cell surface of both A10 and LLC-PK1 cells and could be displaced by excess unlabeled [8-arginine]vasopressin. Rhodamines 4-13 vasopressin Sus scrofa 34-45 2144348-3 1990 The rhodamine-labeled fluorescent vasopressin analog, R-MLVP, initially bound in a diffuse manner at the cell surface of both A10 and LLC-PK1 cells and could be displaced by excess unlabeled [8-arginine]vasopressin. Rhodamines 4-13 vasopressin Sus scrofa 203-214 2134848-5 1990 Double-labeling immunohistochemical and retrograde tracing experiments evidenced that many NPY-LI neurons in the intergeniculate area contained rhodamine microspheres that had been previously injected into the ipsilateral nBOR. Rhodamines 144-153 pro-neuropeptide Y Columba livia 91-94 1969768-1 1990 P-glycoprotein (P-gp) is involved in the transport of a wide variety of organic compounds including a fluorescent dye, rhodamine 6G (RG), as well as anti-cancer drugs. Rhodamines 119-128 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 1969768-1 1990 P-glycoprotein (P-gp) is involved in the transport of a wide variety of organic compounds including a fluorescent dye, rhodamine 6G (RG), as well as anti-cancer drugs. Rhodamines 119-128 ATP binding cassette subfamily B member 1 Homo sapiens 16-20 2307704-3 1990 Fluorescein- or rhodamine-labeled antibody (12C5) specific for the head region (S1) of myosin was used as a marker to identify "embryonic" myosin. Rhodamines 16-25 myosin, heavy chain 15 Gallus gallus 87-93 34916672-2 2022 Here we introduce HaloTag variants with either increased or decreased brightness and fluorescence lifetime compared with HaloTag7 when labeled with rhodamines. Rhodamines 148-158 peptidoglycan recognition protein 1 Homo sapiens 121-129 34229804-6 2021 The result showed that the ratio of TIMP1/MMP-9 (in the range 0.2-1.2) and fluorescence intensity of the probe were negative linear correlation and the effects of BSA-rhodamine accumulation in tumor were individualized differences as well as correlated with the relative ratio of TIMP-1/MMP-9 in serum. Rhodamines 167-176 tissue inhibitor of metalloproteinase 1 Mus musculus 36-41 34229804-6 2021 The result showed that the ratio of TIMP1/MMP-9 (in the range 0.2-1.2) and fluorescence intensity of the probe were negative linear correlation and the effects of BSA-rhodamine accumulation in tumor were individualized differences as well as correlated with the relative ratio of TIMP-1/MMP-9 in serum. Rhodamines 167-176 matrix metallopeptidase 9 Mus musculus 42-47 34229804-6 2021 The result showed that the ratio of TIMP1/MMP-9 (in the range 0.2-1.2) and fluorescence intensity of the probe were negative linear correlation and the effects of BSA-rhodamine accumulation in tumor were individualized differences as well as correlated with the relative ratio of TIMP-1/MMP-9 in serum. Rhodamines 167-176 TIMP metallopeptidase inhibitor 1 Homo sapiens 280-286 34229804-6 2021 The result showed that the ratio of TIMP1/MMP-9 (in the range 0.2-1.2) and fluorescence intensity of the probe were negative linear correlation and the effects of BSA-rhodamine accumulation in tumor were individualized differences as well as correlated with the relative ratio of TIMP-1/MMP-9 in serum. Rhodamines 167-176 matrix metallopeptidase 9 Mus musculus 287-292 2178323-1 1990 Rat ceruloplasmin (rCp) has been labeled with the fluorophores fluorescein and rhodamine by using the isothiocyanate derivatives (FITC, RBITC). Rhodamines 79-88 ceruloplasmin Rattus norvegicus 4-17 2118972-4 1990 In the present work, the uptake of rhodamine 123 by Molt 16 cells stimulated by IFN-gamma or IFN-beta was measured by flow cytometry. Rhodamines 35-44 interferon gamma Homo sapiens 80-89 2118972-4 1990 In the present work, the uptake of rhodamine 123 by Molt 16 cells stimulated by IFN-gamma or IFN-beta was measured by flow cytometry. Rhodamines 35-44 interferon beta 1 Homo sapiens 93-101 34816717-3 2021 Spectroscopic studies revealed trends in fluorophore efficiency based on substitution patterns at the 3"-, 6"-, and 9"-positions, providing insights to aid future designs of rhodamines/rosamines. Rhodamines 174-184 activation induced cytidine deaminase Homo sapiens 152-155 34643369-4 2021 RH-EDA is a hybrid of rhodamine and edaravone and exploits a OH-specific 3-methyl-pyrazolone moiety to control its fluorescence behavior. Rhodamines 22-31 ectodysplasin A Homo sapiens 3-6 34351165-1 2021 This work investigates, for the first time, the application of sonochemically prepared bovine serum albumin (BSA) microspheres (BSAMS) as adsorbents of industrial organic pollutant dyes, such as rhodamine B (RhB), rhodamine 6G (Rh6G), and methylene blue (MB). Rhodamines 214-223 albumin Homo sapiens 94-107 34541849-8 2021 Benefiting from chemical reaction with rhodamine 6G, the AcOH gas sensor displays a short response time. Rhodamines 39-48 gastrin Homo sapiens 62-65 34243072-0 2021 Enhancing the tumor cell selectivity of a rhodamine-decorated iridium(III) complex by conjugating with indomethacin for COX-2 targeted photodynamic therapy. Rhodamines 42-51 mitochondrially encoded cytochrome c oxidase II Homo sapiens 120-125 34339177-3 2021 HaloTag7 reaches almost diffusion-limited labeling rate constants with certain rhodamine substrates, which are more than 2 orders of magnitude higher than those of SNAP-tag for the corresponding substrates. Rhodamines 79-88 peptidoglycan recognition protein 1 Homo sapiens 0-8 34060662-0 2021 Triangular Rhodamine Triads and Their Intrinsic Photophysics Revealed from Gas-phase Ion Fluorescence Experiments. Rhodamines 11-20 gastrin Homo sapiens 75-78 34231571-4 2021 Using Rhodamine 6G (R6G) as a reporter molecule, the SERS enhancement factor (EF) of the TAgNP arrays was found to be as high as 1.2 x 107 and the relative standard deviation was 6.56%. Rhodamines 6-15 seryl-tRNA synthetase 1 Homo sapiens 53-57 34161934-6 2021 Experimental results showed that the limit of detection (LOD) of this composite SERS substrate for Rhodamine 6G (R6G) molecules was as low as 1x10-13 M, and the Raman enhancement factor was 15.68 and 2.87 times that of the AuNP and AgNP monolayer substrates respectively. Rhodamines 99-108 seryl-tRNA synthetase 1 Homo sapiens 80-84 35234756-6 2022 The limit of detection for rhodamine 6G (R6G) molecules adsorbed on the TiO2@Ag SERS substrate is 5 x 10-14 M, and the corresponding SERS enhancement factor can reach 7.61 x 107. Rhodamines 27-36 seryl-tRNA synthetase 1 Homo sapiens 80-84 34254096-4 2021 Upon activation by tumor-associated GGT, the probe releases highly fluorescent rhodamine that is selectively confined in tumors whereby light irradiation leads to effective tumor regression in mice. Rhodamines 79-88 gamma-glutamyltransferase 1 Mus musculus 36-39 34149660-8 2021 Although ABC1 and ABC2 were only moderately (20% and 10%, respectively) expressed compared to the Candida albicans multidrug efflux pump CDR1, overexpression of F. keratoplasticum ABC1 caused even higher resistance levels to certain xenobiotics (e.g., rhodamine 6G and nigericin) than CDR1. Rhodamines 252-261 protein kinase COQ8 Saccharomyces cerevisiae S288C 180-184 34069106-3 2021 Fluorescence microscopy results showed that rhodamine-encapsulated micelle was taken up by brain cancer cells, while competitive inhibition was observed in the presence of free HA and free transferrin. Rhodamines 44-53 transferrin Mus musculus 189-200 35234756-6 2022 The limit of detection for rhodamine 6G (R6G) molecules adsorbed on the TiO2@Ag SERS substrate is 5 x 10-14 M, and the corresponding SERS enhancement factor can reach 7.61 x 107. Rhodamines 27-36 seryl-tRNA synthetase 1 Homo sapiens 133-137 35188523-6 2022 By multiplexing with a permeable rhodamine, we are able to differentiate extra- and intracellular SNAP- and Halo-tags, including those installed on the glucagon-like peptide-1 receptor, a prototypical class B G protein-coupled receptor. Rhodamines 33-42 glucagon like peptide 1 receptor Homo sapiens 152-184 2480910-8 1989 Rhodamine-losing T-lymphoma contained large amounts of the mRNA coding P-glycoprotein, the MDR efflux pump, and demonstrated increased resistance to rhodamine 123, gramicidin D, colchicine, and vincristine, the drugs belonging to the cross-resistance group for the MDR cells. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 71-85 35209208-1 2022 BACKGROUND: rhodamines are dyes widely used as fluorescent tags in cell imaging, probing of mitochondrial membrane potential, and as P-glycoprotein model substrates. Rhodamines 12-22 ATP binding cassette subfamily B member 1 Homo sapiens 133-147 35048136-0 2022 Rhodamine-based chemosensor for Sn2+ detection and its application in nanofibrous film and bioimaging. Rhodamines 0-9 solute carrier family 38 member 5 Homo sapiens 32-35 35048136-1 2022 A simple rhodamine-based compound CK was designed and synthesized as a fluorescent chemosensor for Sn2+ based on Sn2+-mediated cyclization. Rhodamines 9-18 cytidine/uridine monophosphate kinase 1 Homo sapiens 34-36 35048136-1 2022 A simple rhodamine-based compound CK was designed and synthesized as a fluorescent chemosensor for Sn2+ based on Sn2+-mediated cyclization. Rhodamines 9-18 solute carrier family 38 member 5 Homo sapiens 99-102 35048136-1 2022 A simple rhodamine-based compound CK was designed and synthesized as a fluorescent chemosensor for Sn2+ based on Sn2+-mediated cyclization. Rhodamines 9-18 solute carrier family 38 member 5 Homo sapiens 113-116 34985062-2 2022 Two-photon excited fluorescence (TPEF) measurements and quantum chemical calculations reveal excellent two-photon properties of the employed rhodamine derivative. Rhodamines 141-150 transmembrane protein with EGF like and two follistatin like domains 2 Homo sapiens 33-37 2630560-2 1989 Actin of reverting protoplasts was labeled with rhodamine-conjugated phalloidin and observed by conventional fluorescence microscopy and laser scanning confocal microscopy. Rhodamines 48-57 actin Saccharomyces cerevisiae S288C 0-5 2808706-8 1989 In contrast, the labeled SCAD band in YH2065 cells was barely detectable at 6 h and undetectable at 20 h. [35S]Methionine-labeling in the presence of rhodamine 6G demonstrated that SCAD-YH2065 was synthesized as a 44-kD precursor and imported normally into mitochondria, as were the normal SCAD and two other variant SCADs, excluding the possibility that SCAD-YH2065 is a truncated precursor that cannot be imported into mitochondria. Rhodamines 150-159 acyl-CoA dehydrogenase short chain Homo sapiens 25-29 2808706-8 1989 In contrast, the labeled SCAD band in YH2065 cells was barely detectable at 6 h and undetectable at 20 h. [35S]Methionine-labeling in the presence of rhodamine 6G demonstrated that SCAD-YH2065 was synthesized as a 44-kD precursor and imported normally into mitochondria, as were the normal SCAD and two other variant SCADs, excluding the possibility that SCAD-YH2065 is a truncated precursor that cannot be imported into mitochondria. Rhodamines 150-159 acyl-CoA dehydrogenase short chain Homo sapiens 181-185 2808706-8 1989 In contrast, the labeled SCAD band in YH2065 cells was barely detectable at 6 h and undetectable at 20 h. [35S]Methionine-labeling in the presence of rhodamine 6G demonstrated that SCAD-YH2065 was synthesized as a 44-kD precursor and imported normally into mitochondria, as were the normal SCAD and two other variant SCADs, excluding the possibility that SCAD-YH2065 is a truncated precursor that cannot be imported into mitochondria. Rhodamines 150-159 acyl-CoA dehydrogenase short chain Homo sapiens 181-185 2808706-8 1989 In contrast, the labeled SCAD band in YH2065 cells was barely detectable at 6 h and undetectable at 20 h. [35S]Methionine-labeling in the presence of rhodamine 6G demonstrated that SCAD-YH2065 was synthesized as a 44-kD precursor and imported normally into mitochondria, as were the normal SCAD and two other variant SCADs, excluding the possibility that SCAD-YH2065 is a truncated precursor that cannot be imported into mitochondria. Rhodamines 150-159 acyl-CoA dehydrogenase short chain Homo sapiens 181-185 2659755-5 1989 After these reactions, sections were stained with rhodamine-labelled rabbit antihuman IgA antiserum. Rhodamines 50-59 CD79a molecule Homo sapiens 86-89 2531084-4 1989 The lateral mobility of the vasopressin renal-type (V2)-receptor was measured in the basal plasma membrane of cells of the LLC-PK1 porcine epithelial line, using the technique of fluorescence microphotolysis (photobleaching) and a rhodamine-labelled analogue of vasopressin. Rhodamines 231-240 vasopressin Sus scrofa 28-39 2777067-1 1989 Rhodamine-conjugated phalloidin was used to analyze the actin distribution during hyphal formation in Mucor rouxii. Rhodamines 0-9 actin Oryctolagus cuniculus 56-61 3266692-5 1988 Nevertheless, the experiments performed on A431 cells using a fluorescent label--rhodamine--bound to EGF (EGF-R) indicate that CB, though not influencing the initial steps of endocytosis, inhibits the next step--the intracellular transport of EGF-receptor complexes from the trans-Golgi region to lysosomes. Rhodamines 81-90 epidermal growth factor receptor Mus musculus 101-111 2844828-2 1988 Fluorescence polarization and fluorescence photobleaching recovery experiments using rhodamine-labeled actin as a tracer showed that under conditions of low shear (shear rates of 0.05 s-1), a spatial heterogeneity of polymerized actin was observed with respect to fluorescence intensity and the diffusion coefficients with actin mobility becoming quite variable in different regions of the sample. Rhodamines 85-94 actin, beta Gallus gallus 103-108 3058721-3 1988 Comparison of rhodamine-labeled alpha-actinin with coinjected fluorescein-labeled myosin suggested that myosin fluorescence was localized at the A-bands of myofibrils. Rhodamines 14-23 myosin, heavy chain 15 Gallus gallus 104-110 3266692-5 1988 Nevertheless, the experiments performed on A431 cells using a fluorescent label--rhodamine--bound to EGF (EGF-R) indicate that CB, though not influencing the initial steps of endocytosis, inhibits the next step--the intracellular transport of EGF-receptor complexes from the trans-Golgi region to lysosomes. Rhodamines 81-90 epidermal growth factor Mus musculus 101-104 3135511-2 1988 Retrograde transport of rhodamine-labeled fluorescent microspheres following discrete microinjection into the thoracic intermediolateral cell column was combined with immunohistochemistry to determine neuroanatomic location of thyrotropin-releasing hormone-immunoreactive neurons which project to the intermediolateral cell column in the rat. Rhodamines 24-33 thyrotropin releasing hormone Rattus norvegicus 227-256 3689797-1 1987 The effects of caldesmon on structural and dynamic properties of phalloidin-rhodamine-labeled F-actin in single skeletal muscle fibers were investigated by polarized microphotometry. Rhodamines 76-85 caldesmon 1 Homo sapiens 15-24 2894318-2 1988 After 15-20 min of internalization at 37 degrees C, rhodamine-labeled EGF (EGF-Rh) accumulated into large juxtanuclear compartment consisting of closely related vesicles. Rhodamines 52-61 epidermal growth factor Homo sapiens 70-73 2894318-2 1988 After 15-20 min of internalization at 37 degrees C, rhodamine-labeled EGF (EGF-Rh) accumulated into large juxtanuclear compartment consisting of closely related vesicles. Rhodamines 52-61 epidermal growth factor Homo sapiens 75-81 3360988-2 1988 This was done by injecting rhodamine-filled latex microspheres into the nucleus tractus solitarii of rats to retrogradely label neuronal cell bodies and by processing sections from the brains of these animals to determine if the labelled neurons were immunoreactive for the catecholamine-synthesizing enzymes, dopamine-beta-hydroxylase (DBH) and phenylethanolamine-N-methyl transferase (PNMT). Rhodamines 27-36 dopamine beta-hydroxylase Rattus norvegicus 310-335 3360988-2 1988 This was done by injecting rhodamine-filled latex microspheres into the nucleus tractus solitarii of rats to retrogradely label neuronal cell bodies and by processing sections from the brains of these animals to determine if the labelled neurons were immunoreactive for the catecholamine-synthesizing enzymes, dopamine-beta-hydroxylase (DBH) and phenylethanolamine-N-methyl transferase (PNMT). Rhodamines 27-36 dopamine beta-hydroxylase Rattus norvegicus 337-340 3360988-2 1988 This was done by injecting rhodamine-filled latex microspheres into the nucleus tractus solitarii of rats to retrogradely label neuronal cell bodies and by processing sections from the brains of these animals to determine if the labelled neurons were immunoreactive for the catecholamine-synthesizing enzymes, dopamine-beta-hydroxylase (DBH) and phenylethanolamine-N-methyl transferase (PNMT). Rhodamines 27-36 phenylethanolamine-N-methyltransferase Rattus norvegicus 346-385 3360988-2 1988 This was done by injecting rhodamine-filled latex microspheres into the nucleus tractus solitarii of rats to retrogradely label neuronal cell bodies and by processing sections from the brains of these animals to determine if the labelled neurons were immunoreactive for the catecholamine-synthesizing enzymes, dopamine-beta-hydroxylase (DBH) and phenylethanolamine-N-methyl transferase (PNMT). Rhodamines 27-36 phenylethanolamine-N-methyltransferase Rattus norvegicus 387-391 3360988-4 1988 Thus, these two ventrolateral rhombencephalic cell groups accounted for nearly 80% of the total number of rhodamine-bead-labelled DBH-immunoreactive neurons in this series of experiments. Rhodamines 106-115 dopamine beta-hydroxylase Rattus norvegicus 130-133 3360988-5 1988 Only a small number of DBH-immunoreactive neurons of the A2/C2 cell group contained rhodamine-filled latex microspheres. Rhodamines 84-93 dopamine beta-hydroxylase Homo sapiens 23-26 3360988-8 1988 Only small numbers of PNMT-immunoreactive neurons of the C2 and C3 groups were found to contain rhodamine-filled latex microspheres. Rhodamines 96-105 phenylethanolamine-N-methyltransferase Rattus norvegicus 22-26 3782295-0 1986 Formation and alignment of Z lines in living chick myotubes microinjected with rhodamine-labeled alpha-actinin. Rhodamines 79-88 actinin, alpha 4 Gallus gallus 97-110 3667695-1 1987 Myosin light chains labeled with rhodamine are incorporated into myosin-containing structures when microinjected into live muscle and nonmuscle cells. Rhodamines 33-42 myosin, heavy chain 15 Gallus gallus 0-6 3667695-1 1987 Myosin light chains labeled with rhodamine are incorporated into myosin-containing structures when microinjected into live muscle and nonmuscle cells. Rhodamines 33-42 myosin, heavy chain 15 Gallus gallus 65-71 3318045-1 1987 Dynamics of compartmentalization of epidermal growth factor (EGF) in human carcinoma A431 cells during the first hour after initiation of endocytosis was examined by methods of the organelle fractionation on a 20% Percoll gradient and of the microfluorimetric visualization of endocytosis of rhodamine-labeled EGF (EGF-R). Rhodamines 292-301 epidermal growth factor receptor Homo sapiens 61-64 3038101-1 1987 Rhodamines 110 and 123, and rhodamine 110 linked via peptide bonds to Arg, Cbz-Arg and Cbz-Ile-Pr-Arg interact with free base porphyrins or cytochrome C. Rhodamines 0-10 cytochrome c, somatic Homo sapiens 140-152 3038101-1 1987 Rhodamines 110 and 123, and rhodamine 110 linked via peptide bonds to Arg, Cbz-Arg and Cbz-Ile-Pr-Arg interact with free base porphyrins or cytochrome C. Rhodamines 28-37 cytochrome c, somatic Homo sapiens 140-152 3552117-4 1987 This projection originates in large part from phenylethanolamine-N-methyltransferase-immunoreactive cells (C1 adrenergic cluster) as demonstrated by immunohistochemistry combined with the retrograde transport of rhodamine-tagged microbeads. Rhodamines 212-221 phenylethanolamine-N-methyltransferase Rattus norvegicus 46-84 2881297-4 1987 Thy-1 was labeled with rhodamine-conjugated anti-Thy-1 monoclonal antibodies. Rhodamines 23-32 thymus cell antigen 1, theta Mus musculus 0-5 2881297-4 1987 Thy-1 was labeled with rhodamine-conjugated anti-Thy-1 monoclonal antibodies. Rhodamines 23-32 thymus cell antigen 1, theta Mus musculus 49-54 3782295-2 1986 Rhodamine-labeled alpha-actinin microinjected into living cultured chick skeletal myotubes became localized in discrete cellular structures within 1 h and remained specifically associated with structures for up to 4 d, allowing individual identified structures to be followed during development. Rhodamines 0-9 actinin, alpha 4 Gallus gallus 18-31 3758212-2 1986 Rhodamine-labeled actin or alpha-actinin microinjected into embryonic chick cardiac fibroblasts soon became incorporated into stress fibers. Rhodamines 0-9 actin, beta Gallus gallus 18-23 3015981-3 1986 The EGF receptor mutants expressed on the cell surface of the COS cells were labeled with rhodamine-EGF, and the lateral diffusion coefficients of the labeled receptors were determined by the fluorescence photo-bleaching recovery method. Rhodamines 90-99 epidermal growth factor receptor Homo sapiens 4-16 3790516-1 1986 The fluorescence polarization from rhodamine labels specifically attached to the fast-reacting thiol of the myosin cross-bridge in glycerinated muscle fibers has been measured to determine the angular distribution of the cross-bridges in different physiological states of the fibers as a function of temperature. Rhodamines 35-44 myosin heavy chain 14 Homo sapiens 108-114 2432803-1 1986 Rhodamine absorbed to protein was removed from rhodamine-conjugated antibody solutions by adsorption to hydrophobic macroporous beads (Bio-Beads SM-2) following gel permeation chromatography. Rhodamines 0-9 SM2 Homo sapiens 145-149 3760196-7 1986 p alpha-ETF was detected when the cells were labeled in the presence of dinitrophenol or rhodamine 6G. Rhodamines 89-98 electron transfer flavoprotein subunit alpha Homo sapiens 2-11 3516661-7 1986 Indirect immunofluorescence with anti-rbc or antibrain spectrin IgG and goat antirabbit IgG conjugated with rhodamine demonstrated intense staining at the plasma membrane and throughout the cytoplasm of Y-1 cells, with little staining within the nucleus. Rhodamines 108-117 immunoglobulin heavy variable V1-62 Mus musculus 88-91 3540192-3 1986 By staining cells with rhodamine-conjugated phalloidin, we have compared the dynamics of actin localization during the formation of buds and hyphae. Rhodamines 23-32 actin Saccharomyces cerevisiae S288C 89-94 3155961-8 1985 A double immunofluorescence study, involving Fab fragments of IgG L and rhodamine-conjugated antibodies to factor VIII R:Ag, demonstrated the presence of GP IIb-IIIa in megakaryocyte precursor cells. Rhodamines 72-81 integrin subunit alpha 2b Homo sapiens 154-160 3722280-3 1986 The distribution of F-actin filaments in the nurse cells has been studied by staining with rhodamine-conjugated phalloidin. Rhodamines 91-100 Actin 79B Drosophila melanogaster 20-27 3924578-1 1985 The present study describes the synthesis and biological activities of a vasopressin (VP) analog which binds covalently to receptors via a photoreactive p-azido group in position 3 and which contains a rhodamine label in position 8 for localization of hormone-receptor complexes by image-intensified fluorescence microscopy. Rhodamines 202-211 arginine vasopressin Homo sapiens 73-84 3924578-1 1985 The present study describes the synthesis and biological activities of a vasopressin (VP) analog which binds covalently to receptors via a photoreactive p-azido group in position 3 and which contains a rhodamine label in position 8 for localization of hormone-receptor complexes by image-intensified fluorescence microscopy. Rhodamines 202-211 arginine vasopressin Homo sapiens 86-88 3872076-4 1985 OKT6 antibody and S-100 protein were detected simultaneously by double labeling with FITC and rhodamine. Rhodamines 94-103 S100 calcium binding protein A1 Homo sapiens 18-23 3496571-1 1986 Exposure of cultured human retinal pigment epithelial cells to platelet-derived growth factor, nerve growth factor or epidermal growth factor resulted in a time- and dose-dependent alteration in the distribution of actin stained by rhodamine-phalloidin. Rhodamines 232-241 nerve growth factor Homo sapiens 95-114 3496571-1 1986 Exposure of cultured human retinal pigment epithelial cells to platelet-derived growth factor, nerve growth factor or epidermal growth factor resulted in a time- and dose-dependent alteration in the distribution of actin stained by rhodamine-phalloidin. Rhodamines 232-241 epidermal growth factor Homo sapiens 118-141 2995416-1 1985 We have studied the process of transferrin endocytosis in human erythromyeloid cell line K562 using fluorescein (FL) and rhodamine (RD) labeled iron-saturated transferrin (FeTF), and a fluorescein labeled monoclonal antibody to the transferrin receptor (FL-mAB). Rhodamines 132-134 transferrin Homo sapiens 159-170 2995416-1 1985 We have studied the process of transferrin endocytosis in human erythromyeloid cell line K562 using fluorescein (FL) and rhodamine (RD) labeled iron-saturated transferrin (FeTF), and a fluorescein labeled monoclonal antibody to the transferrin receptor (FL-mAB). Rhodamines 132-134 transferrin Homo sapiens 159-170 4040842-1 1985 The pattern of localization of actin filaments was compared in whole mounts of lens epithelium of rabbit and mouse using the fluorescently-labeled actin-specific probe, rhodamine-phalloidin. Rhodamines 169-178 actin Oryctolagus cuniculus 147-152 2579892-2 1985 HB2 fixation was revealed using either a peroxidase- or a rhodamine-labeled anti-mouse immunoglobulin antiserum. Rhodamines 58-67 keratin 82 Homo sapiens 0-3 7019220-1 1981 Rhodamine-conjugated antibodies specific for phenylalanine hydroxylase and serum albumin were employed as cytochemical probes to identify these two proteins in H4 hepatoma cells and in isolated rat hepatocytes. Rhodamines 0-9 phenylalanine hydroxylase Rattus norvegicus 45-70 6329759-5 1984 Treatment with the ionophore monensin was used to determine whether avidin is processed through the Golgi region, which was localized using rhodamine-labeled wheat germ agglutinin. Rhodamines 140-149 avidin Gallus gallus 68-74 6391683-2 1984 The distribution of alpha-actinin in the cells was followed for five days in culture by exposing permeabilized cells to rhodamine-labeled alpha-actinin and also by injecting the labeled alpha-actinin into living myocytes. Rhodamines 120-129 actinin, alpha 4 Gallus gallus 138-151 6391683-2 1984 The distribution of alpha-actinin in the cells was followed for five days in culture by exposing permeabilized cells to rhodamine-labeled alpha-actinin and also by injecting the labeled alpha-actinin into living myocytes. Rhodamines 120-129 actinin, alpha 4 Gallus gallus 138-151 6324146-3 1984 Fluorescent visualization of GnRH receptors in these cells, utilizing a bioactive rhodamine derivative of the hormone, indicated that the fluorescently labeled receptors were initially distributed uniformly on the cell surface and then formed clusters which subsequently internalized (at 37 degrees C) into endocytic vesicles. Rhodamines 82-91 gonadotropin releasing hormone 1 Rattus norvegicus 29-33 6363632-2 1983 Fluorescent labelling of AChRs with rhodamine-conjugated alpha-bungarotoxin (R-Bgt) revealed the presence of irregularly shaped AChR clusters in wing buds at 4 1/2-5 days of incubation. Rhodamines 36-45 cholinergic receptor nicotinic delta subunit Gallus gallus 25-29 6341116-7 1983 Sorted rhodamine-positive cells were cultured and found to be fully functional with respect to subsequent challenge with 30 nM GnRH. Rhodamines 7-16 gonadotropin releasing hormone 1 Rattus norvegicus 127-131 6132682-4 1982 Double label fluorescence microscopy, using fluorescein-Con-A and rhodamine immunofluorescent staining of tubulin or vimentin, indicates that during vesicle migration microtubules and 10-nm filaments are altered in their organization. Rhodamines 66-75 vimentin Rattus norvegicus 117-125 6406516-5 1983 Moreover, rhodamine- or fluorescein-conjugated vinculin, when added to these preparations, became specifically associated with the focal contacts regardless of whether the latter were pretreated with fragmin or not. Rhodamines 10-19 vinculin Gallus gallus 47-55 6305743-4 1983 This rhodamine-labeled antagonist was utilized for the microscopic visualization and localization of LHRH receptors in dispersed rat pituitary cells. Rhodamines 5-14 gonadotropin releasing hormone 1 Rattus norvegicus 101-105 6305743-7 1983 Addition of LHRH (10(-6) M) abolished these processes, indicating specific binding sites for the rhodamine-labeled peptide to the gonadotrope cells. Rhodamines 97-106 gonadotropin releasing hormone 1 Rattus norvegicus 12-16 6761307-3 1982 Microscopic examination of cells stained with rhodamine-labeled anti-Lyt-2 and fluorescein-labeled anti-Lyt-1 was used to measure the proportion of Lyt-1+2-, Lyt-1+2+, and Lyt-1-2+ cells in the spleen and thymus of drug-treated animals. Rhodamines 46-55 CD8 antigen, alpha chain Mus musculus 69-74 7028576-2 1981 A much better detection sensitivity was obtained when Paneth cells were counted by fluorescence microscopy after immunostaining for lysozyme with a rhodamine-labelled rabbit IgG conjugate. Rhodamines 148-157 lysozyme Homo sapiens 132-140 6170323-0 1981 Binding, surface mobility, internalization, and degradation of rhodamine-labeled alpha 2-macroglobulin. Rhodamines 63-72 alpha-2-macroglobulin Mus musculus 81-102 6170323-1 1981 We have used quantitative fluorescence methods to examine the fate of rhodamine-labeled alpha 2-macroglobulin (R-alpha 2 M) after binding to cell-surface receptors on NRK and Swiss 3T3 cells. Rhodamines 70-79 alpha-2-macroglobulin Mus musculus 88-109 7019220-1 1981 Rhodamine-conjugated antibodies specific for phenylalanine hydroxylase and serum albumin were employed as cytochemical probes to identify these two proteins in H4 hepatoma cells and in isolated rat hepatocytes. Rhodamines 0-9 albumin Rattus norvegicus 81-88 6111566-1 1981 After lysis in a Brij 58-polyethylene glycol medium, PtK1 cells are permeable to small molecules, such as erythrosin B, and to proteins, such as rhodamine-labeled FAB, myosin subfragment-1, and tubulin. Rhodamines 145-154 mitogen-activated protein kinase kinase kinase 11 Homo sapiens 53-57 6788382-0 1981 The association of rhodamine - labelled alpha-actinin with actin bundles in demembranated cells. Rhodamines 19-28 actinin alpha 1 Homo sapiens 40-53 6788382-1 1981 Rhodamine-labelled alpha-actinin was specifically bound to actin containing filament bundles of demembranated fibroblasts, and was particularly associated with their termini. Rhodamines 0-9 actinin alpha 1 Homo sapiens 19-32 6788836-0 1981 Cytochemical localization of ornithine decarboxylase with rhodamine or biotin-labeled alpha-difluoromethylornithine. Rhodamines 58-67 ornithine decarboxylase 1 Rattus norvegicus 29-52 6259147-2 1981 The rhodamine-derivatized peptide (Rh-GnRH) retained 40% of the receptor binding activity of [D-Lys6]GnRH, and 50% of the luteinizing hormone-releasing activity assayed in cultured pituitary cells. Rhodamines 4-13 gonadotropin releasing hormone 1 Mus musculus 38-42 6259147-2 1981 The rhodamine-derivatized peptide (Rh-GnRH) retained 40% of the receptor binding activity of [D-Lys6]GnRH, and 50% of the luteinizing hormone-releasing activity assayed in cultured pituitary cells. Rhodamines 4-13 gonadotropin releasing hormone 1 Mus musculus 101-105 7194696-9 1981 The photobleaching recovery curves for rhodamine-labeled bovine serum albumin reveal both an irreversibly bound state and a multiplicity of reversibly bound states. Rhodamines 39-48 albumin Homo sapiens 64-77 6111566-1 1981 After lysis in a Brij 58-polyethylene glycol medium, PtK1 cells are permeable to small molecules, such as erythrosin B, and to proteins, such as rhodamine-labeled FAB, myosin subfragment-1, and tubulin. Rhodamines 145-154 FA complementation group B Homo sapiens 163-166 6932032-4 1980 The rhodamine conjugate of nerve growth factor (R-NGF) binds initially to diffusely distributed mobile receptors (D approximately 8 X 10(-10) cm2/sec) on immature sensory and PC-12 cells. Rhodamines 4-13 nerve growth factor Homo sapiens 27-46 7469415-0 1980 Binding of heparin to antithrombin III: The use of dansyl and rhodamine labels. Rhodamines 62-71 serpin family C member 1 Homo sapiens 22-38 6893813-1 1980 Living cultured fibroblasts were microinjected with rhodamine-labeled smooth muscle alpha-actinin and visualized by video-intensified fluorescence microscopy. Rhodamines 52-61 actinin alpha 1 Homo sapiens 84-97 6932032-4 1980 The rhodamine conjugate of nerve growth factor (R-NGF) binds initially to diffusely distributed mobile receptors (D approximately 8 X 10(-10) cm2/sec) on immature sensory and PC-12 cells. Rhodamines 4-13 nerve growth factor Gallus gallus 50-53 6260433-2 1980 Con A, insulin and EGF receptors co-capped with each other and with cytoplasmic actin; the latter was demonstrated by anti-actin antibody (AAA) traced with fluorescein or rhodamine-labelled goat anti-human globulin. Rhodamines 171-180 LOC521832 Bos taurus 19-22 792981-1 1976 Direct immunofluorescence technique with rhodamine-labelled rabbit anti-gastrin IgG conjugate was used for systematic mapping of the G-cell distribution in 16 resected stomachs (8 gastric ulcer patients and 8 duodenal ulcer patients with uraemia). Rhodamines 41-50 gastrin Homo sapiens 72-79 6153227-2 1980 Rhodamine-conjugated antibodies against fibronectin were used in this study of 22 human kidney biopsies and four histologically normal kidneys in combination with routinely employed fluorescein-conjugated antibodies against immunoglobulins, complement components, and fibrin. Rhodamines 0-9 fibronectin 1 Homo sapiens 40-51 42903-2 1979 When rhodamine-labeled epidermal growth factor is bound to cell surface receptors on confluent monolayers of BALB/c 3T3 cells, it rapidly collects in cell surface clusters and is internalized. Rhodamines 5-14 LOW QUALITY PROTEIN: pro-epidermal growth factor Cricetulus griseus 23-46 42903-6 1979 The polypeptide antibiotic bacitracin inhibits clustering of rhodamine-labeled epidermal growth factor or alpha(2)-macroglobulin at 0.7 mM, and it inhibits approximately 40% of the transglutaminase activity in Chinese hamster ovary cells with a K(i) of 0.03 mM. Rhodamines 61-70 LOW QUALITY PROTEIN: pro-epidermal growth factor Cricetulus griseus 79-102 356052-6 1978 The binding of EGF to the surface of these cells was also visualized by immunofluorescence using rabbit antibodies to EGF and rhodamine-labeled goat anti-rabbit antibodies. Rhodamines 126-135 epidermal growth factor Homo sapiens 15-18 77736-4 1978 With VIM, the cellular uptake and fate of two rhodamine-labeled proteins, concanavalin A and alpha2 macroglobulin, have been followed for up to 24 hr. Rhodamines 46-55 alpha-2-macroglobulin Homo sapiens 93-113 7193921-7 1980 Reaction of unextracted myoblasts directly to human antiplatelet myosin conjugated to rhodamine demonstrated that the most intense reaction also occurred along the lateral edges of both human and chick myoblasts. Rhodamines 86-95 myosin heavy chain 14 Homo sapiens 65-71 160564-1 1979 Particular thiols of the myosin subfragment 1 moieties of single glycerinated muscle fibers are covalently labeled with rhodamine. Rhodamines 120-129 myosin heavy chain 14 Homo sapiens 25-31 152766-17 1978 Staining of isolated mouse or chicken brush borders with rhodamine-antimyosin demonstrates that myosin is localized exclusively in the terminal web. Rhodamines 57-66 myosin, heavy chain 10, non-muscle Gallus gallus 71-77 209452-1 1978 Highly fluorescent analogs of insulin and epidermal growth factor were prepared by the covalent attachment of these peptides to alpha-lactalbumin molecules that were highly substituted (i.e., seven to one) with rhodamine molecules. Rhodamines 211-220 insulin Homo sapiens 30-37 350890-2 1978 Antimyosin raised against human platelet myosin was labeled with rhodamine. Rhodamines 65-74 myosin heavy chain 14 Homo sapiens 4-10 400891-1 1978 High titer, monospecific antibodies to human granulocyte myeloperoxidase, cathepsin G, elastase, lysozyme, and lactoferrin were conjugated with fluorescein and rhodamine and used for immunofluorescent staining of mature neutrophils obtained from 25 patients with acute and chronic leukemia. Rhodamines 160-169 cathepsin G Homo sapiens 74-122 72612-5 1977 Fluorescence microscopy of fixed cells using rhodamine-labeled antibodies indicated that alpha 2M is present in vesicular organelles different from primary lysosomes. Rhodamines 45-54 alpha-2-macroglobulin Homo sapiens 89-97 72612-6 1977 Fluorescence microscopy of living cells shows that rhodamine-labeled alpha 2M (rhodamine-alpha 2M) is taken up into similar structures. Rhodamines 51-60 alpha-2-macroglobulin Homo sapiens 69-77 72612-6 1977 Fluorescence microscopy of living cells shows that rhodamine-labeled alpha 2M (rhodamine-alpha 2M) is taken up into similar structures. Rhodamines 51-60 alpha-2-macroglobulin Homo sapiens 89-97 72612-6 1977 Fluorescence microscopy of living cells shows that rhodamine-labeled alpha 2M (rhodamine-alpha 2M) is taken up into similar structures. Rhodamines 79-88 alpha-2-macroglobulin Homo sapiens 69-77 72612-6 1977 Fluorescence microscopy of living cells shows that rhodamine-labeled alpha 2M (rhodamine-alpha 2M) is taken up into similar structures. Rhodamines 79-88 alpha-2-macroglobulin Homo sapiens 89-97 803528-4 1975 This was demonstrated best through the use of rhodamine-conjugated Fab fragments of IgM- and IgD-specific antisera which were both capped by the idiotypic antiserum. Rhodamines 46-55 FA complementation group B Homo sapiens 67-70 32469522-1 2020 he aim of the present paper is to study the effect of common excipients on the permeability of atenolol (as drug absorbed mainly by passive diffusion) and rhodamine (as P-Glycoprotein substrate). Rhodamines 155-164 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 169-183 33783243-5 2021 This assay is based on the polarization of light emitted by a fluorescent rhodamine tag conjugated to a peptide corresponding to the N-terminal region of ATG16L1 (ATG16L1-N). Rhodamines 74-83 autophagy related 16 like 1 Homo sapiens 154-161 33783243-5 2021 This assay is based on the polarization of light emitted by a fluorescent rhodamine tag conjugated to a peptide corresponding to the N-terminal region of ATG16L1 (ATG16L1-N). Rhodamines 74-83 autophagy related 16 like 1 Homo sapiens 163-172 33722692-4 2021 Targeted anti-CD71-CPSNPs encapsulated with the fluorophore, Rhodamine WT, were preferentially internalized by breast cancer cells in co-cultures with osteoblasts. Rhodamines 61-70 transferrin receptor Homo sapiens 14-18 33629859-2 2021 Herein, we demonstrate that Rhodamine 6G (Rh-6G) dye conjugated DNA aptamer-attached gold nanostar (GNS)-based distance-dependent nanoparticle surface energy transfer (NSET) spectroscopy has the capability of rapid diagnosis of specific SARS-CoV-2 spike recombinant antigen or SARS-CoV-2 spike protein pseudotyped baculovirus within 10 min. Rhodamines 28-37 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 248-253 33629859-2 2021 Herein, we demonstrate that Rhodamine 6G (Rh-6G) dye conjugated DNA aptamer-attached gold nanostar (GNS)-based distance-dependent nanoparticle surface energy transfer (NSET) spectroscopy has the capability of rapid diagnosis of specific SARS-CoV-2 spike recombinant antigen or SARS-CoV-2 spike protein pseudotyped baculovirus within 10 min. Rhodamines 28-37 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 288-293 33383428-8 2021 On molecular docking results, triclosan and the fluorescent used as substrate (rhodamine) presented high affinity with all ABC proteins family tested, showing a greater affinity with ABCC2. Rhodamines 79-88 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 Danio rerio 183-188 32706571-3 2020 The highly ordered tip-capped nanopore arrays can induce the high sensitive and reproducible Raman signal, whose enhanced factor for rhodamine 6G (R6G) at 1358 cm-1 is 4.46x106. Rhodamines 133-142 TOR signaling pathway regulator Homo sapiens 19-22 33064113-1 2020 A rhodamine appended Fe(iii)-catecholate complex Fe(RhoCat)3 is reported as a smart dual-modal T1 MRI-optical imaging probe. Rhodamines 2-11 general transcription factor IIE subunit 1 Homo sapiens 49-60 32779644-6 2020 We hypothesized that the Fe3+ ion was expected to induce the spirolactam ring-opening of the rhodamine unit due to its Lewis acid nature and preferable interactions with the N and O atoms present in NR as well as PNR. Rhodamines 93-102 trace amine associated receptor 5 Homo sapiens 213-216 32575097-7 2020 Rhodamine 6-G was detected by SERS up to 10-12M with an analytical enhancement factor of 109for both materials using a 633 nm laser operating at 0.85 mW (5% of the nominal power). Rhodamines 0-9 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 30-34 32373846-3 2020 Here we report on a simple gas-phase model system, synthesized with the rhodamine 575 (R575+) and rhodamine 640 (R640+) FRET pair and a covalent linker with four methylenes, R575+-(CH2)4-R640+. Rhodamines 72-81 gastrin Homo sapiens 27-30 32930207-4 2020 The probe RHPN consists of a rhodamine analogue and an arylhydrazide group as a response site for ONOO-. Rhodamines 29-38 rhophilin Rho GTPase binding protein 1 Homo sapiens 10-14 32373846-3 2020 Here we report on a simple gas-phase model system, synthesized with the rhodamine 575 (R575+) and rhodamine 640 (R640+) FRET pair and a covalent linker with four methylenes, R575+-(CH2)4-R640+. Rhodamines 98-107 gastrin Homo sapiens 27-30 32131933-3 2020 Results The rBMECs,stimulated by glutamine,showed a high expression of P-gp(F=1.924,P=0.020)/Mdr1a(F=1.788,P=0.019) compared to the normal rBMECs.The treatment with 25.0(F=1.924,P=0.025;F=1.788,P=0.017) and 50.0 mug/mul(F=1.924,P=0.035;F=1.788,P=0.026) alpha-asarone significantly depressed the expression of P-gp/Mdr1a.The treatment with 25.0 and 50.0 mug/mul alpha-asarone significantly increased intracellular accumulation of Rhodamine 123 by 40% and 60% respectively. Rhodamines 429-438 phosphoglycolate phosphatase Rattus norvegicus 71-75 32478727-6 2020 Rhodamine-conjugated globular actin (G-actinRed) is diluted and loaded into a microneedle. Rhodamines 0-9 Actin 79B Drosophila melanogaster 30-35 32404156-6 2020 Rhodamine-labeled rhPRG4 was incubated with OA synoviocytes +- anti-CD44 or isotype control antibodies and cellular uptake of rhPRG4 was determined following a 30-min incubation and alpha-SMA expression following a 24-h incubation. Rhodamines 0-9 CD44 antigen Mus musculus 68-72 32404156-6 2020 Rhodamine-labeled rhPRG4 was incubated with OA synoviocytes +- anti-CD44 or isotype control antibodies and cellular uptake of rhPRG4 was determined following a 30-min incubation and alpha-SMA expression following a 24-h incubation. Rhodamines 0-9 actin alpha 2, smooth muscle, aorta Mus musculus 182-191 32232949-9 2020 Hence, the rotationally symmetric architecture of P-gp, which determines duality in ATP binding and rhodamine 123 interaction, also forms the basis for the existence of two independently operating outer gates. Rhodamines 100-109 ATP binding cassette subfamily B member 1 Homo sapiens 50-54 32140458-0 2020 A Fluorescent and Colorimetric Chemosensor for Hg2+ Based on Rhodamine 6G With a Two-Step Reaction Mechanism. Rhodamines 61-70 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 47-50 31714050-5 2019 Anti-EpCAM antibodies and galactose-rhodamine-polyacrylamide nanoparticles (Gal-Rh-PAA NPs) specifically recognizing ASGPR are modified on the surface of a graphene film that quenches the rhodamine fluorescence. Rhodamines 36-45 asialoglycoprotein receptor 1 Homo sapiens 117-122 31419747-4 2020 In this study, using rhodamine as the acceptor and phenothiazine as the donor, we synthesized a novel mitochondrial-targeted near infrared (NIR) fluorescent probe, MIT-PZR. Rhodamines 21-30 myelin protein zero like 1 Homo sapiens 168-171 31714050-6 2019 HCC-CTCs can be captured by anti-EpCAM antibodies and endocytose Gal-Rh-PAA NPs, recovering the rhodamine fluorescence. Rhodamines 96-105 epithelial cell adhesion molecule Homo sapiens 33-38 31451653-3 2019 FCP-1 links fluorescein and rhodamine dyes through a Tris[(2-pyridyl)methyl]amine bridge. Rhodamines 28-37 FCP1 Homo sapiens 0-5 31039840-0 2019 A Novel Morpholine-Based Rhodamine Fluorescent Chemosensor for the Rapid Detection of Hg2+ Ions. Rhodamines 25-34 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 86-89 31775672-2 2019 Fluorocoxib A, a rhodamine-conjugated analog of indomethacin, is a novel fluorescent imaging agent that selectively targets cyclooxygenase-2 (COX-2)-expressing cancers. Rhodamines 17-26 prostaglandin-endoperoxide synthase 2 Mus musculus 124-140 31775672-2 2019 Fluorocoxib A, a rhodamine-conjugated analog of indomethacin, is a novel fluorescent imaging agent that selectively targets cyclooxygenase-2 (COX-2)-expressing cancers. Rhodamines 17-26 prostaglandin-endoperoxide synthase 2 Mus musculus 142-147 31434345-6 2019 The enhanced cellular uptake and selective accumulation of TLS (Res) and DLS (Res) into the mitochondria were demonstrated by behavioral observation of rhodamine-labeled TLS or DLS, using confocal microscopy, and by resveratrol quantification in the intracellular organelle, using LC-MS/MS. Rhodamines 152-161 FUS RNA binding protein Homo sapiens 59-62 31087712-4 2019 The activity of P-glycoprotein (P-gp), as one of the membrane transporters, was determined by the rhodamine 123 (Rho 123) assay. Rhodamines 98-107 ATP binding cassette subfamily B member 1 Homo sapiens 16-30 31087712-4 2019 The activity of P-glycoprotein (P-gp), as one of the membrane transporters, was determined by the rhodamine 123 (Rho 123) assay. Rhodamines 98-107 ATP binding cassette subfamily B member 1 Homo sapiens 32-36 31454967-9 2019 Lyophilization of rhodamine-loaded PBCA-MB with sucrose and PVP showed that the presence of the dye does not affect the efficiency of freeze-drying, and that the dye is efficiently retained upon MB lyophilization. Rhodamines 18-27 PBCA Homo sapiens 35-39 31434345-6 2019 The enhanced cellular uptake and selective accumulation of TLS (Res) and DLS (Res) into the mitochondria were demonstrated by behavioral observation of rhodamine-labeled TLS or DLS, using confocal microscopy, and by resveratrol quantification in the intracellular organelle, using LC-MS/MS. Rhodamines 152-161 FUS RNA binding protein Homo sapiens 170-173 31166936-3 2019 Due to the enhanced visible-light absorption and efficient separation of photo-generated holes and electrons, the SnS2-SnO2 heterostructures display excellent photocatalytic performance for the degradation of rhodamine (RhB) under visible-light irradiation. Rhodamines 209-218 sodium voltage-gated channel alpha subunit 11 Homo sapiens 114-118 31054496-1 2019 A photoinduced electron transfer (PET) and chelation-enhanced fluorescence (CHEF) regulated rhodamine-azobenzene chemosensor (L) was synthesized for chemoselective detection of Al3+, Cr3+, and Cu2+ by UV-Visible absorption study whereas Al3+ and Cr3+ by fluorimetric study in EtOH-H2O solvent. Rhodamines 92-101 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 183-186 31054496-1 2019 A photoinduced electron transfer (PET) and chelation-enhanced fluorescence (CHEF) regulated rhodamine-azobenzene chemosensor (L) was synthesized for chemoselective detection of Al3+, Cr3+, and Cu2+ by UV-Visible absorption study whereas Al3+ and Cr3+ by fluorimetric study in EtOH-H2O solvent. Rhodamines 92-101 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 246-249 31054496-3 2019 This is first report on rhodamine-azobenzene based Cr3+ chemosensor. Rhodamines 24-33 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 51-54 30947123-6 2019 Ten selected non-hydrolysable derivatives were able to inhibit the P-gp-mediated rhodamine-123 efflux on K562/DOX cells, and the evaluation of their apparent permeability and ATP consumption on other cell lines suggested that the compounds can behave as unambiguous or not transported substrates. Rhodamines 81-90 phosphoglycolate phosphatase Homo sapiens 67-71 30958597-7 2019 Moreover, the level of active STAT3 was elevated in rhodamine 123 negative subpopulations of CSCs sorted from three melanoma cell lines. Rhodamines 52-61 signal transducer and activator of transcription 3 Homo sapiens 30-35 31002479-3 2019 PDL is a laser that emits yellow light using Rhodamine dye as it is lasing medium. Rhodamines 45-54 programmed cell death 1 Homo sapiens 0-3 30806015-2 2019 Herein, two derivatives of low-cost rhodamine, called sulforhodamine 101 (SR101) and sulforhodamine B (SRB), are applied as cathode interfacial layers (CILs) to effectively improve the charge-carrier transportation and collection, reduce the work function (WF) of Al counter electrode, and decrease the series resistance and charge recombination in the PSCs. Rhodamines 36-45 chaperonin containing TCP1 subunit 4 Homo sapiens 85-101 30806015-2 2019 Herein, two derivatives of low-cost rhodamine, called sulforhodamine 101 (SR101) and sulforhodamine B (SRB), are applied as cathode interfacial layers (CILs) to effectively improve the charge-carrier transportation and collection, reduce the work function (WF) of Al counter electrode, and decrease the series resistance and charge recombination in the PSCs. Rhodamines 36-45 chaperonin containing TCP1 subunit 4 Homo sapiens 103-106 30952726-3 2019 MATERIALS AND METHODS: In order to determine the feasibility of using an aptamer against mucin 1 (aptA) as carrier of the cytotoxic compound 1,10-phenanthroline to MCF-7 cells, as a potential radiosensitizer, was studied in experiments using circular dichroism and rhodamine labelling by fluorescent microscopy and flow cytometry. Rhodamines 265-274 mucin 1, cell surface associated Homo sapiens 89-96 30776197-3 2019 By introducing two additional rhodamine moieties at the termini, the resulting conjugate could also detect Hg2+ ions in a highly selective manner. Rhodamines 30-39 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 107-110 30776197-4 2019 Upon excitation at the BODIPY core, the fluorescence emission of rhodamine at 580 nm was observed and the intensity increased substantially upon addition of Hg2+ ions due to inhibition of the PET process followed by highly efficient fluorescence resonance energy transfer (FRET) from the BODIPY core to the rhodamine moieties. Rhodamines 65-74 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 157-160 30776197-4 2019 Upon excitation at the BODIPY core, the fluorescence emission of rhodamine at 580 nm was observed and the intensity increased substantially upon addition of Hg2+ ions due to inhibition of the PET process followed by highly efficient fluorescence resonance energy transfer (FRET) from the BODIPY core to the rhodamine moieties. Rhodamines 307-316 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 157-160 30881339-5 2019 The cells were incubated with a pH-rhodamine-labeled human recombinant monoclonal GluN1 IgG1 autoantibody (GluN1-aAbpH-rhod) genetically engineered from clonally expanded intrathecal plasma cells from a patient with anti-NMDAR encephalitis, and the pH-rhodamine fluorescence was tracked over time. Rhodamines 35-44 glutamate ionotropic receptor NMDA type subunit 1 Homo sapiens 107-112 30613850-8 2019 Graphical Abstract Schematic representation of Hg2+ detection by rhodamine based sensor. Rhodamines 65-74 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 47-50 29130339-5 2019 Mechanistically, Ethyl lucidenates A could increase the intracellular accumulation of vincristine in K562/A02 cells through inhibiting the P-glycoprotein mediated drug-transport activity by rhodamine accumulation assay and cell cycle analysis. Rhodamines 190-199 ATP binding cassette subfamily B member 1 Homo sapiens 139-153 30688455-5 2019 A total of 7 of 17 flavonoid substrates stimulated the P-gp efflux of rhodamine 123, and most substrates increased P-gp expression in KB/MDR cells. Rhodamines 70-79 ATP binding cassette subfamily B member 1 Homo sapiens 55-59 30688455-5 2019 A total of 7 of 17 flavonoid substrates stimulated the P-gp efflux of rhodamine 123, and most substrates increased P-gp expression in KB/MDR cells. Rhodamines 70-79 ATP binding cassette subfamily B member 1 Homo sapiens 115-119 29773368-6 2018 In addition, the multifunctional NPs increased the permeability of rhodamine 123 because the thiomer THL-fucoidan in the NPs inhibited P-glycoprotein. Rhodamines 67-76 ATP binding cassette subfamily B member 1 Homo sapiens 135-149 30627799-0 2019 A novel tryptamine-appended rhodamine-based chemosensor for selective detection of Hg2+ present in aqueous medium and its biological applications. Rhodamines 28-37 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 83-86 30881339-5 2019 The cells were incubated with a pH-rhodamine-labeled human recombinant monoclonal GluN1 IgG1 autoantibody (GluN1-aAbpH-rhod) genetically engineered from clonally expanded intrathecal plasma cells from a patient with anti-NMDAR encephalitis, and the pH-rhodamine fluorescence was tracked over time. Rhodamines 35-44 glutamate ionotropic receptor NMDA type subunit 1 Homo sapiens 82-87 30538042-7 2019 Meanwhile, it was also increased the retention of P-gp substrates DOX and Rhodamine 123 (Rho-123) while did not affect the ATPase activity. Rhodamines 74-83 ATP binding cassette subfamily B member 1 Homo sapiens 50-54 30259171-4 2018 The composite was used for SERS detection of rhodamine 6G and two antibacterial drugs (ceftriaxone and sulfadimethoxine). Rhodamines 45-54 seryl-tRNA synthetase 1 Homo sapiens 27-31 30233326-6 2018 Our results showed that ischemia produced BBB damage and MMP-2/9 upregulation was colocalized with Rhodamine-dextran leakage. Rhodamines 99-108 matrix metallopeptidase 2 Rattus norvegicus 57-62 30293961-0 2018 Relationship between the fluorescence intensity of rhodamine-labeled orexin A and the calcium responses in cortical neurons: An in vivo two-photon calcium imaging study. Rhodamines 51-60 hypocretin Mus musculus 69-77 30293961-3 2018 Here, we synthesized a rhodamine-labeled orexin A compound, enabling us to quantify the amount of orexin binding to its receptors, OX1 and OX2, which principally couple to the Gq/11 protein. Rhodamines 23-32 hypocretin Mus musculus 41-49 30293961-3 2018 Here, we synthesized a rhodamine-labeled orexin A compound, enabling us to quantify the amount of orexin binding to its receptors, OX1 and OX2, which principally couple to the Gq/11 protein. Rhodamines 23-32 hypocretin Mus musculus 41-47 30293961-3 2018 Here, we synthesized a rhodamine-labeled orexin A compound, enabling us to quantify the amount of orexin binding to its receptors, OX1 and OX2, which principally couple to the Gq/11 protein. Rhodamines 23-32 NAD(P)H dehydrogenase, quinone 1 Mus musculus 131-134 30293961-3 2018 Here, we synthesized a rhodamine-labeled orexin A compound, enabling us to quantify the amount of orexin binding to its receptors, OX1 and OX2, which principally couple to the Gq/11 protein. Rhodamines 23-32 CD200 antigen Mus musculus 139-142 30293961-5 2018 Applying rhodamine-labeled orexin A (10 muM) to the cortical surface gradually and heterogeneously increased both the intensity of the rhodamine fluorescence and [Ca2+]i. Rhodamines 9-18 hypocretin Mus musculus 27-35 30293961-5 2018 Applying rhodamine-labeled orexin A (10 muM) to the cortical surface gradually and heterogeneously increased both the intensity of the rhodamine fluorescence and [Ca2+]i. Rhodamines 135-144 hypocretin Mus musculus 27-35 30293961-6 2018 Calcium responses started simultaneously with the increase in rhodamine-labeled orexin fluorescence and reached a plateau within several minutes. Rhodamines 62-71 hypocretin Mus musculus 80-86 29709579-2 2018 In this study we measured the inhibitory behaviour of a set of known drugs towards P-gp by using three different probe substrates (digoxin, Hoechst 33,342 and rhodamine 123). Rhodamines 159-168 phosphoglycolate phosphatase Homo sapiens 83-87 29698604-4 2018 Cellular uptake of PEG-CNA-RHO was detected within 30 s, and the amount internalized increased over the course of 1 h. Moreover, these copolymers were internalized within cells to a higher degree than controls consisting of either rhodamine tagged PEG or the rhodamine alone. Rhodamines 231-240 protein phosphatase 3, catalytic subunit, alpha isoform Mus musculus 23-26 30166110-13 2018 ATE-Hex reduced the rhodamine efflux in MES-SA/Dx5 cells, indicating that ATE-Hex could reduce the expression of P-gp. Rhodamines 20-29 hematopoietically expressed homeobox Homo sapiens 4-7 29458585-1 2018 We report the design and synthesis of a novel chemosensor (Rh6G-Cin) rhodamine-based indicator for selective detection of Zn2+ ion. Rhodamines 69-78 pyridoxal phosphatase Homo sapiens 64-67 30166110-13 2018 ATE-Hex reduced the rhodamine efflux in MES-SA/Dx5 cells, indicating that ATE-Hex could reduce the expression of P-gp. Rhodamines 20-29 hematopoietically expressed homeobox Homo sapiens 78-81 30166110-13 2018 ATE-Hex reduced the rhodamine efflux in MES-SA/Dx5 cells, indicating that ATE-Hex could reduce the expression of P-gp. Rhodamines 20-29 phosphoglycolate phosphatase Homo sapiens 113-117 29698604-4 2018 Cellular uptake of PEG-CNA-RHO was detected within 30 s, and the amount internalized increased over the course of 1 h. Moreover, these copolymers were internalized within cells to a higher degree than controls consisting of either rhodamine tagged PEG or the rhodamine alone. Rhodamines 259-268 protein phosphatase 3, catalytic subunit, alpha isoform Mus musculus 23-26 29748326-5 2018 After a single intravenous injection of VFI, plasma volume and mGFR can be determined on the basis of the plasma pharmacokinetics of the rhodamine derivative and fluorescein carboxymethylated dextrans, respectively. Rhodamines 137-146 Rap guanine nucleotide exchange factor (GEF) 5 Mus musculus 63-67 30109181-5 2018 Furthermore, olmutinib could also increase the retention of doxorubicin (DOX) and rhodamine 123 (Rho 123) in ABC transporter subfamily G member 2 (ABCG2)-overexpressing cells. Rhodamines 82-91 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 147-152 29289977-7 2018 These included a population of CCR4-CCR6- effector/memory CD4+ T cells expressing intermediate levels of the Th1-related chemokine receptor CXCR3 and abnormally high multi-drug resistance type 1 transporter (MDR1) activity as assessed by a rhodamine 123 excretion assay. Rhodamines 240-249 C-C motif chemokine receptor 4 Homo sapiens 31-35 29763760-0 2018 Multispectroscopic and bioimaging approach for the interaction of rhodamine 6G capped gold nanoparticles with bovine serum albumin. Rhodamines 66-75 albumin Homo sapiens 117-130 29858657-8 2018 Carcinoembryonic antigen in sample was detected sensitively by using sensitization of rhodamine dye Rh123 as signal amplification strategy. Rhodamines 86-95 CEA cell adhesion molecule 3 Homo sapiens 0-24 32254242-2 2018 Herein, we synthesized a novel phenyl-substituted imidazole-fused rhodamine analogue RV-1 with a long absorption wavelength at 573 nm and a large Stokes shift of about 82 nm for monitoring the changes in cellular viscosity. Rhodamines 66-75 Friend virus susceptibility 1 Mus musculus 85-89 29808393-0 2018 A Rhodamine Derivative Based Chemosensor with High Selectivity and Quick Respond to Cr3+ in Aqueous Solution. Rhodamines 2-11 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 84-87 29808393-1 2018 In this paper, a new kind of colorimetric chemsensor aiming at detecting Cr3+ has been synthesized, and it is based on the "Off-On" effect of a rhodamine derivative. Rhodamines 144-153 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 73-76 29808393-4 2018 According to the fitting curve based on Benesi-Hildebrand equation and working curve of absorption strength in UV-vis spectrum, the binding pattern of Cr3+ and the rhodamine derivative follows a 1:1 stoichiometry. Rhodamines 164-173 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 151-154 29289977-7 2018 These included a population of CCR4-CCR6- effector/memory CD4+ T cells expressing intermediate levels of the Th1-related chemokine receptor CXCR3 and abnormally high multi-drug resistance type 1 transporter (MDR1) activity as assessed by a rhodamine 123 excretion assay. Rhodamines 240-249 C-C motif chemokine receptor 6 Homo sapiens 36-40 29725247-8 2018 Salmonella significantly decreased the efflux capabilities of P-gp, as based on the influx of Rhodamine 123 assay. Rhodamines 94-103 ATP binding cassette subfamily B member 1 Homo sapiens 62-66 29534440-5 2018 Additionally, all of them except ATx 3 (+), caused similar results when the accumulation of the P-gp fluorescent substrate was evaluated after pre-incubating cells with the test compounds for 24 h, significantly reducing the rhodamine 123 intracellular accumulation as a result of a significant increase in P-gp activity. Rhodamines 225-234 ataxin 3 Homo sapiens 33-38 29421572-7 2018 Two long-lasting P-gp pump modulators (9 and 10) were identified; they were able to inhibit remarkably the P-gp substrate rhodamine-123 efflux on the resistant K562/DOX cell line after 60 min. Rhodamines 122-131 phosphoglycolate phosphatase Homo sapiens 17-21 29421572-7 2018 Two long-lasting P-gp pump modulators (9 and 10) were identified; they were able to inhibit remarkably the P-gp substrate rhodamine-123 efflux on the resistant K562/DOX cell line after 60 min. Rhodamines 122-131 phosphoglycolate phosphatase Homo sapiens 107-111 29183127-1 2017 Amino pyridine-based rhodamine conjugate (APR) has been developed as a first chemosensor for selective detection and quantification of L-4-Hydroxyproline (Hyp). Rhodamines 21-30 ribosomal protein L4 Homo sapiens 135-153 29458405-14 2018 Dacomitinib was found to significantly increase the accumulation of ABCG2 probe substrates [doxorubicin (DOX),Rhodamine 123 (Rho 123) and Hoechst 33342] by inhibiting the transporter efflux function. Rhodamines 110-119 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 68-73 29132113-6 2018 The new approach takes advantage of Forster Resonance Energy Transfer (FRET) between, as the donor, a fluorescein-like diarsenical probe able to covalently bind a tetracysteine motif fused to the recombinant PDE5 catalytic domain and, as the acceptor, a rhodamine probe covalently bound to the pseudosubstrate cGMPS. Rhodamines 254-263 phosphodiesterase 5A Homo sapiens 208-212 29132113-7 2018 The FRET efficiency decreases when a competitive ligand binds the PDE5 catalytic site and displaces the cGMPS-rhodamine conjugate. Rhodamines 110-119 phosphodiesterase 5A Homo sapiens 66-70 29132113-8 2018 We have structurally investigated the PDE5/cGMPS-rhodamine complex by molecular modelling and have used the FRET signal to quantitatively characterize its binding equilibrium. Rhodamines 49-58 phosphodiesterase 5A Homo sapiens 38-42 29291440-7 2018 Oxime and particularly oxime ether formation strongly increased their inhibitory activity on the efflux of rhodamine 123 by P-glycoprotein (P-gp), while the new ecdysteroid lactam did not interfere with the efflux function. Rhodamines 107-116 ATP binding cassette subfamily B member 1 Homo sapiens 124-138 29291440-7 2018 Oxime and particularly oxime ether formation strongly increased their inhibitory activity on the efflux of rhodamine 123 by P-glycoprotein (P-gp), while the new ecdysteroid lactam did not interfere with the efflux function. Rhodamines 107-116 ATP binding cassette subfamily B member 1 Homo sapiens 140-144 29534440-5 2018 Additionally, all of them except ATx 3 (+), caused similar results when the accumulation of the P-gp fluorescent substrate was evaluated after pre-incubating cells with the test compounds for 24 h, significantly reducing the rhodamine 123 intracellular accumulation as a result of a significant increase in P-gp activity. Rhodamines 225-234 ATP binding cassette subfamily B member 1 Homo sapiens 96-100 29534440-5 2018 Additionally, all of them except ATx 3 (+), caused similar results when the accumulation of the P-gp fluorescent substrate was evaluated after pre-incubating cells with the test compounds for 24 h, significantly reducing the rhodamine 123 intracellular accumulation as a result of a significant increase in P-gp activity. Rhodamines 225-234 ATP binding cassette subfamily B member 1 Homo sapiens 307-311 29498663-6 2018 Furthermore, capsaicin and piperine increased the intracellular accumulation of the fluorescent P-glycoprotein (P-gp) substrates rhodamine and calcein and inhibited their efflux from the MDR cell lines. Rhodamines 129-138 ATP binding cassette subfamily B member 1 Homo sapiens 96-110 29498663-6 2018 Furthermore, capsaicin and piperine increased the intracellular accumulation of the fluorescent P-glycoprotein (P-gp) substrates rhodamine and calcein and inhibited their efflux from the MDR cell lines. Rhodamines 129-138 ATP binding cassette subfamily B member 1 Homo sapiens 112-116 29419294-4 2018 The shift of the rhodamine pi-pi* absorption maxima in going from Pt-RDM1 to Pt-RDM3 correlates well with the HOMO-LUMO energy gap measured in electrochemical experiments. Rhodamines 17-26 RAD52 motif containing 1 Homo sapiens 69-73 29379908-7 2018 Impressively, the noted approach not only enabled the use of a new kind of enzyme substrate for ELISAs but also allowed the detection of human TNF-alpha at concentrations over 54-fold lower than that possible on commercial microwell plates primarily due to the better detectability of the rhodamine dye. Rhodamines 289-298 tumor necrosis factor Homo sapiens 143-152 29282978-3 2018 The effective permeability of the typical P-gp substrate rhodamine 123 (R123) in colon was significantly increased from (1.69 +- 0.22) x 10-5 cm/s in the control group to (3.39 +- 0.417) x 10-5 cm/s (p < 0.01) in the 3.5 mM IP6 group. Rhodamines 57-66 ATP binding cassette subfamily B member 1 Homo sapiens 42-46 29146563-7 2018 Km and Vmax of P-gp mediated basolateral-to-apical (B-A) flux of rhodamine 123 were estimated to 332+-124muM and 111+-16pmol cm-2 min-1 (n=3, total N=6), respectively. Rhodamines 65-74 ATP binding cassette subfamily B member 1 Homo sapiens 15-19 29128272-8 2018 LA treatment minimizes STX cytotoxicity, evaluated by trypan blue and MTT assay and both STX and STX-LA treatments were efficient to induce P-gp activity measured by rhodamine 123 dye extrusion. Rhodamines 166-175 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 Homo sapiens 89-92 29128272-8 2018 LA treatment minimizes STX cytotoxicity, evaluated by trypan blue and MTT assay and both STX and STX-LA treatments were efficient to induce P-gp activity measured by rhodamine 123 dye extrusion. Rhodamines 166-175 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 Homo sapiens 89-92 29128272-8 2018 LA treatment minimizes STX cytotoxicity, evaluated by trypan blue and MTT assay and both STX and STX-LA treatments were efficient to induce P-gp activity measured by rhodamine 123 dye extrusion. Rhodamines 166-175 ATP binding cassette subfamily B member 1 Homo sapiens 140-144 30114704-9 2018 Mechanistically, the intracellular accumulations of doxorubicin and Rhodamine 123 were increased in ABCG2-overexpressing S1-MI-80 cells with the presence of PCI29732. Rhodamines 68-77 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 100-105 28823086-0 2017 An Efficient Fluorescence "Turn-On" Chemosensor Comprising of Coumarin and Rhodamine Moieties for Al3+ and Hg2. Rhodamines 75-84 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 107-110 28823086-5 2017 Graphical Abstract A potent fluorescence "turn-on" receptor (HL) based on rhodamine and coumarin moieties for the detection of Hg2+ and Al3+ is synthesized and characterized. Rhodamines 74-83 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 127-130 29541662-4 2018 Thus, we provide solubility data on two prototypical P-gp substrates, digoxin and rhodamine 123, representing P-gp substrates with a relatively low- and high-aqueous solubility, respectively. Rhodamines 82-91 ATP binding cassette subfamily B member 1 Homo sapiens 53-57 29541662-4 2018 Thus, we provide solubility data on two prototypical P-gp substrates, digoxin and rhodamine 123, representing P-gp substrates with a relatively low- and high-aqueous solubility, respectively. Rhodamines 82-91 ATP binding cassette subfamily B member 1 Homo sapiens 110-114 28947254-3 2017 Here, we have internalized a rhodamine-based sensor RSL+ into living cells and monitored the mitochondrial ATP levels in cultured mouse embryonic fibroblasts. Rhodamines 29-38 regulator of sex limited protein-Slp Mus musculus 52-55 28624525-3 2017 Zebrafish (Danio rerio) treated with the Pxr agonist pregnenolone 16alpha-carbonitrile (PCN) showed decreased P-gp (zebrafish Abcb4) and CYP3A (zebrafish Cyp3a65) mRNA levels after 48h exposure; however, treatment with PCN also resulted in increased hepatic MDR/MXR functional activity (i.e. increased Rhodamine 123 efflux) in vivo. Rhodamines 302-311 nuclear receptor subfamily 1, group I, member 2 Danio rerio 41-44 28825091-3 2017 P(RD-CZ) exhibits excellent selectivity for Hg2+ ions compared with Cd2+, Cu2+ Zn2+, and Fe3+ using the potentiometric technique, which depends on the increasing charge carrier transport through rhodamine-bound Hg2+ with a limit of detection (LOD) of 9.77 x 10-8 M. The P(RD-CZ) polymer film also exhibits a distinct color change from orange to purple, which is detectable even by the naked eye, in the presence of Hg2+ ions. Rhodamines 195-204 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 44-47 28825091-3 2017 P(RD-CZ) exhibits excellent selectivity for Hg2+ ions compared with Cd2+, Cu2+ Zn2+, and Fe3+ using the potentiometric technique, which depends on the increasing charge carrier transport through rhodamine-bound Hg2+ with a limit of detection (LOD) of 9.77 x 10-8 M. The P(RD-CZ) polymer film also exhibits a distinct color change from orange to purple, which is detectable even by the naked eye, in the presence of Hg2+ ions. Rhodamines 195-204 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 211-214 28825091-3 2017 P(RD-CZ) exhibits excellent selectivity for Hg2+ ions compared with Cd2+, Cu2+ Zn2+, and Fe3+ using the potentiometric technique, which depends on the increasing charge carrier transport through rhodamine-bound Hg2+ with a limit of detection (LOD) of 9.77 x 10-8 M. The P(RD-CZ) polymer film also exhibits a distinct color change from orange to purple, which is detectable even by the naked eye, in the presence of Hg2+ ions. Rhodamines 195-204 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 211-214 28577240-0 2017 A Rhodamine-Based Fluorescent Chemosensor for the Detection of Pb2+, Hg2+ and Cd2. Rhodamines 2-11 CD2 molecule Homo sapiens 78-81 28405849-6 2017 However, accumulation of adriamycin and rhodamine 123 were increased which suggested the depression of P-gp activity. Rhodamines 40-49 ATP binding cassette subfamily B member 1 Homo sapiens 103-107 28860472-5 2017 Surface imprinting was employed to construct a transferrin (TRA)-imprinted layer on the surface of rhodamine doped silica nanoparticles. Rhodamines 99-108 transferrin Homo sapiens 47-58 28860472-5 2017 Surface imprinting was employed to construct a transferrin (TRA)-imprinted layer on the surface of rhodamine doped silica nanoparticles. Rhodamines 99-108 transferrin Homo sapiens 60-63 28823086-1 2017 A potent fluorescence "turn-on" receptor (HL) based on rhodamine and coumarin moieties for the detection of Hg2+ and Al3+ is synthesized by condensation of rhodamine 6G hydrazide and 4-hydroxy-3-acetylcoumarin. Rhodamines 55-64 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 108-111 28132103-5 2017 The C1236T, G2677A/T, and C3435T SNPs were determined, and the functionality of P-gp was assessed by flow cytometry (Rhodamine efflux assay). Rhodamines 117-126 ATP binding cassette subfamily B member 1 Homo sapiens 80-84 28726724-0 2017 Theoretical Studies on Two-Photon Fluorescent Hg2+ Probes Based on the Coumarin-Rhodamine System. Rhodamines 80-89 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 46-49 28726724-2 2017 In the present work, the optical properties of two newly-synthesized Hg2+ chemosensors based on the coumarin-rhodamine system (named Pro1 and Pro2) were systematically investigated using time-dependent density functional theory. Rhodamines 109-118 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 69-72 28726724-2 2017 In the present work, the optical properties of two newly-synthesized Hg2+ chemosensors based on the coumarin-rhodamine system (named Pro1 and Pro2) were systematically investigated using time-dependent density functional theory. Rhodamines 109-118 lamin A/C Homo sapiens 133-137 28533092-9 2017 Similarly, the presence of DM did not alter the locations of other drug-binding sites since the thiol reactive forms of the substrates verapamil or rhodamine labeled the same sites in transmembrane segments 5 (I306C for verapamil) and 6 (F343C for rhodamine) whether P-gp was in native membranes or in detergent micelles. Rhodamines 148-157 ATP binding cassette subfamily B member 1 Homo sapiens 267-271 28620179-5 2017 Quantitative analysis based on SERS detection describes an excellent reproducibility with an intensity variation less than 7% at 1649 cm-1 of Rhodamine 6G. Rhodamines 142-151 seryl-tRNA synthetase 1 Homo sapiens 31-35 28368059-0 2017 Pd2+ fluorescent sensors based on amino and imino derivatives of rhodamine and improvement of water solubility by the formation of inclusion complexes with beta-cyclodextrin. Rhodamines 65-74 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 0-3 28088116-6 2017 Furthermore, a Cr3+-responsive rhodamine derivative (CRD) was modified on the devised UCNPs surface to fabricate the colorimetric probe by luminescent resonance energy transfer (LRET) process. Rhodamines 31-40 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 15-18 28235604-9 2017 The expression and function of P-gp were measured by Western blotting, quantitative real-time polymerase chain reaction (qRT-PCR) and flow cytometry using rhodamine efflux. Rhodamines 155-164 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 31-35 28225099-5 2017 Using this approach, the muMD measures droplets at a rate of 106 droplets per sec (phi = 166 mL h-1) in 120 parallel microfluidic channels and achieves a limit of detection LOD = 1 muM Rhodamine dye, sufficient for typical droplet based assays. Rhodamines 185-194 latexin Homo sapiens 25-28 28303028-4 2017 Mechanistically, alectinib increased the intracellular accumulation of ABCB1/ABCG2 substrates such as doxorubicin (DOX) and Rhodamine 123 (Rho 123) by inhibiting the efflux function of the transporters in ABCB1- or ABCG2-overexpressing cells but not in their parental sensitive cells. Rhodamines 124-133 ATP binding cassette subfamily B member 1 Homo sapiens 71-76 28303028-4 2017 Mechanistically, alectinib increased the intracellular accumulation of ABCB1/ABCG2 substrates such as doxorubicin (DOX) and Rhodamine 123 (Rho 123) by inhibiting the efflux function of the transporters in ABCB1- or ABCG2-overexpressing cells but not in their parental sensitive cells. Rhodamines 124-133 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 77-82 28030801-9 2017 We reveal that SPP1 is overexpressed in glioma initiating cells defined by high rhodamine 123 efflux, sphere forming capacity and stemness marker expression. Rhodamines 80-89 secreted phosphoprotein 1 Homo sapiens 15-19 27821506-3 2017 Here we identify a subset of memory CD4+ T cells capable of effluxing cellular toxins, including rhodamine (Rho), through the multidrug efflux protein MDR1 (also known as P-glycoprotein and ABCB1). Rhodamines 97-106 CD4 molecule Homo sapiens 36-39 28104238-4 2017 The proposed multi-stacking strategy was verified under a fluorescence microscope using Rhodamine 6G as the model analyte and a sensitivity enhancement factor (SEF) of up to 217 was achieved. Rhodamines 88-97 transcription factor CP2 Homo sapiens 128-158 28104238-4 2017 The proposed multi-stacking strategy was verified under a fluorescence microscope using Rhodamine 6G as the model analyte and a sensitivity enhancement factor (SEF) of up to 217 was achieved. Rhodamines 88-97 transcription factor CP2 Homo sapiens 160-163 27821506-3 2017 Here we identify a subset of memory CD4+ T cells capable of effluxing cellular toxins, including rhodamine (Rho), through the multidrug efflux protein MDR1 (also known as P-glycoprotein and ABCB1). Rhodamines 97-106 ATP binding cassette subfamily B member 1 Homo sapiens 151-155 27821506-3 2017 Here we identify a subset of memory CD4+ T cells capable of effluxing cellular toxins, including rhodamine (Rho), through the multidrug efflux protein MDR1 (also known as P-glycoprotein and ABCB1). Rhodamines 97-106 ATP binding cassette subfamily B member 1 Homo sapiens 190-195 28068095-4 2017 In addition, 7a induced the mitochondrial tyrosine nitration and the intracellular accumulation of rhodamine 123 by inhibiting P-gp activity in K562/A02 cells. Rhodamines 99-108 phosphoglycolate phosphatase Homo sapiens 127-131 28772466-1 2017 Nonlinear optical properties of a series of newly-synthesized molecular fluorescent probes for Hg2+ containing the same acceptor (rhodamine group) are analyzed by using time-dependent density functional theory in combination with analytical response theory. Rhodamines 130-139 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 95-98 27810576-11 2017 Eight of the tested PPCPs showed effects on Abcb4 ATPase activity indicating that their effects in the dye accumulation assay may have indeed resulted from interference with Abcb4-mediated rhodamine 123 efflux. Rhodamines 189-198 ATP-binding cassette, sub-family B (MDR/TAP), member 4 Danio rerio 44-49 27810576-11 2017 Eight of the tested PPCPs showed effects on Abcb4 ATPase activity indicating that their effects in the dye accumulation assay may have indeed resulted from interference with Abcb4-mediated rhodamine 123 efflux. Rhodamines 189-198 ATPase H+ transporting V1 subunit C1a Danio rerio 50-56 27810576-11 2017 Eight of the tested PPCPs showed effects on Abcb4 ATPase activity indicating that their effects in the dye accumulation assay may have indeed resulted from interference with Abcb4-mediated rhodamine 123 efflux. Rhodamines 189-198 ATP-binding cassette, sub-family B (MDR/TAP), member 4 Danio rerio 174-179 28109303-11 2017 Huh7 and MDA-MB231 cells displayed a significantly higher Rhodamine density in the cytoplasmic phagosomes and this suggests that the mechanism of uptake of large DNA by cancer cells is likely endocytosis. Rhodamines 58-67 MIR7-3 host gene Homo sapiens 0-4 28114946-9 2017 Specifically, the rate of permeability of Rhodamine 123 across the BBB model (0.6 +- 0.1 x 10-3, n = 4), increased 14-fold in the presence of the P-gp inhibitor verapamil (14.7 +- 7.5 x 10-3, n = 3) and eightfold with the addition of Cyclosporine A (8.8 +- 1.8 x 10-3, n = 3). Rhodamines 42-51 phosphoglycolate phosphatase Homo sapiens 146-150 27026527-4 2017 In 3D ileal enteroid culture and cell culture models (MDCK, IEC-6 and IPEC-J2 cells), extrusion events were suppressed by EGF, as determined by direct counting of released cells or rhodamine-phalloidin labeling of condensed actin rings. Rhodamines 181-190 epidermal growth factor Sus scrofa 122-125 27864369-4 2017 Despite dramatic reduction in rhodamine 123 and calcein-AM transport, the linker-shortened mutant P-gp possesses basal ATPase activity and binds ATP only in its N-terminal nucleotide-binding domain. Rhodamines 30-39 phosphoglycolate phosphatase Mus musculus 98-102 27678410-8 2017 R or racemic form of tolterodine and R-tamsulosin concentration-dependently increased P-gp protein expression; the latter also enhanced P-gp efflux function in a rhodamine-based efflux assay. Rhodamines 162-171 ATP binding cassette subfamily B member 1 Homo sapiens 136-140 27101017-4 2016 This QD/Eu-MOF is found to be an effective catalyst to complete the degradation of Rhodamine 6G dye within 50 min. Rhodamines 83-92 lysine acetyltransferase 8 Homo sapiens 11-14 27720954-1 2016 In this present study, the secretory transport of P-gp substrates, rhodamine 123 and digoxin, was evaluated using a Caco-2/HT29-MTX co-culture characterized by an efflux mechanism and a paracellular permeability closer to the human intestinal barrier compared to the Caco-2 monolayer gold standard. Rhodamines 67-76 phosphoglycolate phosphatase Homo sapiens 50-54 27720954-3 2016 Labrasol ALF and Gelucire 44/14 in saline buffer significantly decreased to 83% and 62%, the P-gp-mediated transport of rhodamine 123 across the co-culture, respectively. Rhodamines 122-131 afamin Homo sapiens 10-13 27720954-3 2016 Labrasol ALF and Gelucire 44/14 in saline buffer significantly decreased to 83% and 62%, the P-gp-mediated transport of rhodamine 123 across the co-culture, respectively. Rhodamines 122-131 phosphoglycolate phosphatase Homo sapiens 95-99 27348457-7 2016 P-gp activities were assayed by rhodamine 123 cellular retention. Rhodamines 32-41 phosphoglycolate phosphatase Rattus norvegicus 0-4 27886150-6 2016 P-gp efflux activity and P-gp ATPase activity were measured using a rhodamine 123 (Rh-123) accumulation assay and a Pgp-Glo assay; respectively. Rhodamines 68-77 PGP Canis lupus familiaris 0-4 29345889-11 2016 Accumulation of rhodamine encapsulated EGFR-targeted cationic liposomes was observed throughout the primary tumor bed after systemic injection. Rhodamines 16-25 epidermal growth factor receptor Homo sapiens 39-43 26810690-3 2016 Materials and methods In Caco-2 cell experiments, the effects of baicalin and baicalein on P-gp activity were investigated using a P-gp substrate, rhodamine 123 and non-substrate fluorescein Na, by determining their intracellular fluorescence accumulation, and their effects on P-gp expression were determined using flow cytometry. Rhodamines 147-156 ATP binding cassette subfamily B member 1 Homo sapiens 91-95 27760768-6 2016 We then examined clathrin-mediated endocytosis after ILK inhibition using rhodamine-conjugated transferrin. Rhodamines 74-83 transferrin Rattus norvegicus 95-106 27545217-8 2016 The reversal of MDR by AKBA was evident in an intracellular increase in Rhodamine (Rh123), indicating that the activity of P-glycoprotein (P-gp) was blocked. Rhodamines 72-81 ATP binding cassette subfamily B member 1 Homo sapiens 123-137 27545217-8 2016 The reversal of MDR by AKBA was evident in an intracellular increase in Rhodamine (Rh123), indicating that the activity of P-glycoprotein (P-gp) was blocked. Rhodamines 72-81 ATP binding cassette subfamily B member 1 Homo sapiens 139-143 27857347-3 2016 The fabricated MoS<sub>2</sub>@Au NPs with higher surface area exhibit excellent Raman enhanced effect for aromatic organic molecules (rhodamine 6G and crystal violet) and achieve the best when the monolayer MoS<sub>2</sub>@AuNPs was obtained. Rhodamines 147-156 MOS proto-oncogene, serine/threonine kinase Homo sapiens 15-18 27857347-3 2016 The fabricated MoS<sub>2</sub>@Au NPs with higher surface area exhibit excellent Raman enhanced effect for aromatic organic molecules (rhodamine 6G and crystal violet) and achieve the best when the monolayer MoS<sub>2</sub>@AuNPs was obtained. Rhodamines 147-156 MOS proto-oncogene, serine/threonine kinase Homo sapiens 220-223 27267282-1 2016 A novel rhodamine-based dual probe Rh-2 for trivalent ferric ions (Fe(3+)) was successfully designed and synthesized, which exhibited a highly sensitive and selective recognition towards Fe(3+) with an enhanced fluorescence emission in methanol-water media (v/v=7/3, pH=7.2). Rhodamines 8-17 Rh associated glycoprotein Homo sapiens 35-39 27669824-8 2016 The multistacking was verified under a fluorescence microscope using Rhodamine 6G as the analyte, revealing a sensitivity enhancement factor (SEF) of 110. Rhodamines 69-78 transcription factor CP2 Homo sapiens 110-140 27669824-8 2016 The multistacking was verified under a fluorescence microscope using Rhodamine 6G as the analyte, revealing a sensitivity enhancement factor (SEF) of 110. Rhodamines 69-78 transcription factor CP2 Homo sapiens 142-145 27060462-0 2016 Measurement of Rhodamine 123 in Three-Dimensional Organoids: A Novel Model for P-Glycoprotein Inhibitor Screening. Rhodamines 15-24 ATP binding cassette subfamily B member 1 Homo sapiens 79-93 27060462-3 2016 In this study, a rapid, sensitive and efficient method to measure rhodamine 123 (Rh123, P-gp substrate) in 3D organoids was developed to analyse P-gp-mediated drug transport. Rhodamines 66-75 ATP binding cassette subfamily B member 1 Homo sapiens 88-92 27060462-3 2016 In this study, a rapid, sensitive and efficient method to measure rhodamine 123 (Rh123, P-gp substrate) in 3D organoids was developed to analyse P-gp-mediated drug transport. Rhodamines 66-75 ATP binding cassette subfamily B member 1 Homo sapiens 145-149 27196753-3 2016 Mechanistically, osimertinib increased the intracellular accumulations of doxorubicin (DOX) and Rhodamine 123 (Rho 123) by inhibiting the efflux function of the transporters in ABCB1- or ABCG2-overexpressing cells but not in their parental sensitive cells. Rhodamines 96-105 ATP binding cassette subfamily B member 1 Homo sapiens 177-182 27117116-1 2016 Functionalized giant unilamellar vesicles (GUVs) containing a fluorescence dye Rhodamine 6G is proposed as a marker in sandwich-type immunoassay for bovine serum albumin (BSA) and lipocalin-2 (LCN2). Rhodamines 79-88 albumin Homo sapiens 156-175 27117116-1 2016 Functionalized giant unilamellar vesicles (GUVs) containing a fluorescence dye Rhodamine 6G is proposed as a marker in sandwich-type immunoassay for bovine serum albumin (BSA) and lipocalin-2 (LCN2). Rhodamines 79-88 lipocalin 2 Homo sapiens 180-191 27117116-1 2016 Functionalized giant unilamellar vesicles (GUVs) containing a fluorescence dye Rhodamine 6G is proposed as a marker in sandwich-type immunoassay for bovine serum albumin (BSA) and lipocalin-2 (LCN2). Rhodamines 79-88 lipocalin 2 Homo sapiens 193-197 27044313-5 2016 To test this, we studied the effects of several alkylated rhodamines on the drug resistance of yeast Saccharomyces cerevisiae We found that octylrhodamine synergetically increases toxicity of Pdr5p substrate-clotrimazole, while the others were less effective. Rhodamines 58-68 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 192-197 27044313-6 2016 Next, we compared the contributions of three major pleiotropic ABC-transporters (Pdr5p, Yor1p, Snq2p) on the accumulation of the alkylated rhodamines. Rhodamines 139-149 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 81-86 27044313-6 2016 Next, we compared the contributions of three major pleiotropic ABC-transporters (Pdr5p, Yor1p, Snq2p) on the accumulation of the alkylated rhodamines. Rhodamines 139-149 ATP-binding cassette transporter YOR1 Saccharomyces cerevisiae S288C 88-93 27044313-6 2016 Next, we compared the contributions of three major pleiotropic ABC-transporters (Pdr5p, Yor1p, Snq2p) on the accumulation of the alkylated rhodamines. Rhodamines 139-149 ATP-binding cassette transporter SNQ2 Saccharomyces cerevisiae S288C 95-100 27044313-8 2016 Interestingly, among the tested alkylated rhodamines, inactivation of Pdr5p had the strongest effect on the accumulation of octylrhodamine inside the cells, which is consistent with the fact that clotrimazole is a substrate of Pdr5p. Rhodamines 42-52 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 70-75 27001764-0 2016 Geographical Distribution of MDR1 Expression in Leishmania Isolates, from Greece and Cyprus, Measured by the Rhodamine-123 Efflux Potential of the Isolates, Using Flow Cytometry. Rhodamines 109-118 ATP binding cassette subfamily B member 1 Homo sapiens 29-33 27077878-4 2016 14/16 of these P-gp inhibitors were found to increase rhodamine 123 accumulation in P-gp-overexpressing MCF7R cells, thus allowing the determination of their P-gp inhibitory potential, i.e., their half maximal inhibitor concentration (IC50) value towards P-gp-mediated transport of the dye. Rhodamines 54-63 ATP binding cassette subfamily B member 1 Homo sapiens 15-19 27077878-4 2016 14/16 of these P-gp inhibitors were found to increase rhodamine 123 accumulation in P-gp-overexpressing MCF7R cells, thus allowing the determination of their P-gp inhibitory potential, i.e., their half maximal inhibitor concentration (IC50) value towards P-gp-mediated transport of the dye. Rhodamines 54-63 ATP binding cassette subfamily B member 1 Homo sapiens 84-88 27077878-4 2016 14/16 of these P-gp inhibitors were found to increase rhodamine 123 accumulation in P-gp-overexpressing MCF7R cells, thus allowing the determination of their P-gp inhibitory potential, i.e., their half maximal inhibitor concentration (IC50) value towards P-gp-mediated transport of the dye. Rhodamines 54-63 ATP binding cassette subfamily B member 1 Homo sapiens 84-88 27077878-4 2016 14/16 of these P-gp inhibitors were found to increase rhodamine 123 accumulation in P-gp-overexpressing MCF7R cells, thus allowing the determination of their P-gp inhibitory potential, i.e., their half maximal inhibitor concentration (IC50) value towards P-gp-mediated transport of the dye. Rhodamines 54-63 ATP binding cassette subfamily B member 1 Homo sapiens 84-88 26288998-6 2016 The enhancement ratios of Papp calculated from the ratio between Papp of rhodamine 123 in the presence of P-gp inhibitors and Papp of rhodamine 123 alone were 2.36, 2.09, and 1.84-fold in the presence of PAA-Cys-2MNA, PAA-Cys, and PAA, respectively. Rhodamines 73-82 ATP binding cassette subfamily B member 1 Homo sapiens 106-110 27140215-3 2016 The bone-abrading method was used to detect the effects of intracerebroventricular application of 40 mug/kg bw TNF-alpha on cerebral venular leakage of fluorescein isothiocyanate (FITC)- albulmin and the rolling and adhesion of leukocytes on venules with fluorescence tracer rhodamine 6G. Rhodamines 275-284 tumor necrosis factor Mus musculus 111-120 26258802-6 2016 The enhancement ratios of Papp calculated from the ratio between Papp of rhodamine 123 in the presence of P-gp inhibitors and Papp of rhodamine 123 alone were 2.36, 2.09, and 1.84-fold in the presence of PAA-Cys-2MNA, PAA-Cys, and PAA, respectively. Rhodamines 73-82 ATP binding cassette subfamily B member 1 Homo sapiens 106-110 26968974-0 2016 Effects of Polyoxyethylene Alkyl Ethers on the Intestinal Transport and Absorption of Rhodamine 123: A P-glycoprotein Substrate by In Vitro and In Vivo Studies. Rhodamines 86-95 ATP binding cassette subfamily B member 1 Homo sapiens 103-117 26555574-0 2016 Environmentally Robust Rhodamine Reporters for Probe-based Cellular Detection of the Cancer-linked Oxidoreductase hNQO1. Rhodamines 23-32 NAD(P)H quinone dehydrogenase 1 Homo sapiens 114-119 26687436-3 2015 In contrast to common logic, we used SERS intensity gradients of Rhodamine 6G to quantitatively calculate the concentration of chloride ions at specific positions on a microfluidic chip. Rhodamines 65-74 seryl-tRNA synthetase 1 Homo sapiens 37-41 27212149-1 2016 OBJECTIVE: The aim of this work was to verify the usefulness and efficacy of treating superficial vascular lesions of the face using rhodamine intense pulsed light (r-IPL). Rhodamines 133-142 pleckstrin homology like domain family A member 2 Homo sapiens 167-170 26486517-7 2015 Pgp function was assessed by a rhodamine efflux assay and (99m)Tc-sestamibi scintigraphy. Rhodamines 31-40 ATP binding cassette subfamily B member 1 Homo sapiens 0-3 26506420-4 2015 Furthermore, cetuximab markedly increased intracellular accumulation of doxorubicin (DOX) and rhodamine 123 (Rho 123) in ABCB1-overexpressing MDR cancer cells in a concentration-dependent manner. Rhodamines 94-103 ATP binding cassette subfamily B member 1 Homo sapiens 121-126 26402516-1 2015 A rhodamine-based molecule, Rh-OH, is synthesized. Rhodamines 2-11 ras homolog family member H Homo sapiens 28-33 26153782-8 2015 In five EBV-T-LPDs patients, P-gp function was detected by Rhodamine-123 efflux assay in these cells. Rhodamines 59-68 ATP binding cassette subfamily B member 1 Homo sapiens 29-33 26462065-1 2015 Using apoferritin (AFt) as a carrier, a novel ratiometric luminescence probe based on luminescence resonance energy transfer (LRET) between a Tb(3+) complex (PTTA-Tb(3+)) and a rhodamine derivative (Rh-NO), PTTA-Tb(3+)@AFt-Rh-NO, has been designed and prepared for the specific recognition and time-gated luminescence detection of nitric oxide (NO) in living samples. Rhodamines 177-186 ferritin heavy chain 1 Homo sapiens 6-17 26462065-1 2015 Using apoferritin (AFt) as a carrier, a novel ratiometric luminescence probe based on luminescence resonance energy transfer (LRET) between a Tb(3+) complex (PTTA-Tb(3+)) and a rhodamine derivative (Rh-NO), PTTA-Tb(3+)@AFt-Rh-NO, has been designed and prepared for the specific recognition and time-gated luminescence detection of nitric oxide (NO) in living samples. Rhodamines 177-186 ferritin heavy chain 1 Homo sapiens 19-22 26265061-7 2015 P-gp inhibitory potential of Pl-g-CH was proved by flow cytometry and fluorescence microscopy where the much enhanced fluorescence intensity of Rhodamine 123 (Rho-123, P-gp substrate) was observed in the presence of Pl-g-CH. Rhodamines 144-153 phosphoglycolate phosphatase Homo sapiens 0-4 26265061-7 2015 P-gp inhibitory potential of Pl-g-CH was proved by flow cytometry and fluorescence microscopy where the much enhanced fluorescence intensity of Rhodamine 123 (Rho-123, P-gp substrate) was observed in the presence of Pl-g-CH. Rhodamines 144-153 phosphoglycolate phosphatase Homo sapiens 168-172 26291333-6 2015 FD18 (1 muM) can increase accumulation of doxorubicin by 2.7-fold, daunorubicin (2.1-fold), and rhodamine 123 (5.2-fold) in LCC6MDR. Rhodamines 96-105 latexin Homo sapiens 8-11 25841120-3 2015 Using CA125 as the antigen and Rhodamine-6G (R6G)-conjugated immunogolds, a SERS immunosensor was self-assembled by antigen-antibody interaction. Rhodamines 31-40 mucin 16, cell surface associated Homo sapiens 6-11 26174773-4 2015 Cys residues were introduced at 12 positions in hSERT to enable covalent attachment of a rhodamine-based fluorophore. Rhodamines 89-98 solute carrier family 6 member 4 Homo sapiens 48-53 26757548-5 2015 When pretreatment with MRP2 siRNA-3 or P-gp siRNA-2, the efflux of methotrexate or rhodamine decreased significantly and the intra-cellular concentration increased. Rhodamines 83-92 ATP binding cassette subfamily C member 2 Homo sapiens 23-35 26757548-5 2015 When pretreatment with MRP2 siRNA-3 or P-gp siRNA-2, the efflux of methotrexate or rhodamine decreased significantly and the intra-cellular concentration increased. Rhodamines 83-92 phosphoglycolate phosphatase Homo sapiens 39-43 26295572-3 2015 The results showed that the rhodamine 123 (Rh123) accumulation, an indicator of P-gp activity, in Caco-2, KBv and RBMECs was increased by (-)CLA (1 or 5 mumol/L) at 8.2%-28.5%, but reduced by (+)CLA at 11.7%-25.9%, showing stereoselectivity in their regulation of P-gp activity. Rhodamines 28-37 ATP binding cassette subfamily B member 1 Homo sapiens 80-84 26295572-3 2015 The results showed that the rhodamine 123 (Rh123) accumulation, an indicator of P-gp activity, in Caco-2, KBv and RBMECs was increased by (-)CLA (1 or 5 mumol/L) at 8.2%-28.5%, but reduced by (+)CLA at 11.7%-25.9%, showing stereoselectivity in their regulation of P-gp activity. Rhodamines 28-37 ATP binding cassette subfamily B member 1 Homo sapiens 264-268 25995342-3 2015 EXPERIMENTAL DESIGN: ABCB1 efflux activity was determined using a rhodamine efflux assay. Rhodamines 66-75 ATP binding cassette subfamily B member 1 Homo sapiens 21-26 26350141-5 2015 Microarray and real-time PCR analysis showed that ABCB1 mRNA is upregulated in these cells, and P-glycoprotein (P-gp) expression as well as function were confirmed by immunoblot and rhodamine exclusion assays. Rhodamines 182-191 ATP binding cassette subfamily B member 1 Homo sapiens 50-55 26350141-5 2015 Microarray and real-time PCR analysis showed that ABCB1 mRNA is upregulated in these cells, and P-glycoprotein (P-gp) expression as well as function were confirmed by immunoblot and rhodamine exclusion assays. Rhodamines 182-191 ATP binding cassette subfamily B member 1 Homo sapiens 96-110 26350141-5 2015 Microarray and real-time PCR analysis showed that ABCB1 mRNA is upregulated in these cells, and P-glycoprotein (P-gp) expression as well as function were confirmed by immunoblot and rhodamine exclusion assays. Rhodamines 182-191 ATP binding cassette subfamily B member 1 Homo sapiens 112-116 26018271-1 2015 OBJECTIVE: To investigate the role of capsaicin in regulating permeation of P-gp substrate rhodamine 123 (R123) across the jejunum, ileum and colon membranes of rats. Rhodamines 91-100 phosphoglycolate phosphatase Rattus norvegicus 76-80 26219569-7 2015 Interestingly, all resistant cells showed the induction of P-gp at the protein and RNA levels, which was associated with an increased efflux of the P-gp substrate rhodamine 123 (Rho123). Rhodamines 163-172 ATP binding cassette subfamily B member 1 Homo sapiens 59-63 26219569-7 2015 Interestingly, all resistant cells showed the induction of P-gp at the protein and RNA levels, which was associated with an increased efflux of the P-gp substrate rhodamine 123 (Rho123). Rhodamines 163-172 ATP binding cassette subfamily B member 1 Homo sapiens 148-152 25981393-4 2015 We also prepare dye-based SERS nanoprobes by sandwiching a typical Raman reporter such as Rhodamine B (RhB), Crystal Violet (CV) and Rhodamine 6G (R6G) between the nanostars and the nGO coating. Rhodamines 90-99 seryl-tRNA synthetase 1 Homo sapiens 26-30 25725134-6 2015 The P-gp efflux efficiency was assessed by rhodamine 123 transport. Rhodamines 43-52 phosphoglycolate phosphatase Homo sapiens 4-8 25857708-3 2015 Rhodamine derivatives are validated fluorescent probes for measurement of mitochondrial membrane potential and also Pgp function. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 116-119 25857708-4 2015 The aim of this study was to investigate whether 2"[(18)F]-fluoroethylrhodamine B ((18)FRB) a halogenated rhodamine derivative previously synthesized for PET assessment of myocardial perfusion preserved its Pgp substrate character. Rhodamines 70-79 ATP binding cassette subfamily B member 1 Homo sapiens 207-210 25857708-8 2015 Dissipation of the mitochondrial proton gradient by a proton ionophore CCCP decreased the accumulation of rhodamine 123 (R123) and (18)FRB into Pgp(-) cells. Rhodamines 106-115 ATP binding cassette subfamily B member 1 Homo sapiens 144-147 25586740-3 2015 In the present study, miR-10a silencing in human DDP-resistant lung cancer A549/DDP cells was demonstrated to improve DDP sensitivity, apoptosis, intracellular rhodamine-123 content as well as the expression and activity of caspase-3/8. Rhodamines 160-169 microRNA 10a Homo sapiens 22-29 25765837-7 2015 The lignans can increase the retention of the P-gp substrate rhodamine 123 in CEM/ADR 5000 cells, indicating that lignans can inhibit the activity of P-gp. Rhodamines 61-70 phosphoglycolate phosphatase Homo sapiens 46-50 26197581-1 2015 In the present paper, the authors studied fluorescence resonance energy transfer (FRET) phenomenon between silver triangular nanoplates and bovine serum albumin (BSA)/Rhodamine 6G fluorescence complex, and established a fluorescence method for the detection of cobalt ions. Rhodamines 167-176 albumin Homo sapiens 147-160 26197581-2 2015 We found that when increasing the silver triangular nanoplates added to certain concentrations of fluorescent bovine serum albumin (BSA)/Rhodamine 6G complex, the fluorescence of Rhodamine 6G would be quenched up to 80% due to the FRET between the quencher and donor. Rhodamines 137-146 albumin Homo sapiens 117-130 25829763-7 2015 Further, the ability of ES to inhibit multi drug resistant (MDR) transporters (ABC-B1 and ABC-G2) was determined by Rhodamine (Rho) and Mitoxantrone (MXR) efflux assays. Rhodamines 116-125 ATP binding cassette subfamily B member 1 Homo sapiens 79-85 25829763-7 2015 Further, the ability of ES to inhibit multi drug resistant (MDR) transporters (ABC-B1 and ABC-G2) was determined by Rhodamine (Rho) and Mitoxantrone (MXR) efflux assays. Rhodamines 116-125 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 90-96 25829763-7 2015 Further, the ability of ES to inhibit multi drug resistant (MDR) transporters (ABC-B1 and ABC-G2) was determined by Rhodamine (Rho) and Mitoxantrone (MXR) efflux assays. Rhodamines 116-119 ATP binding cassette subfamily B member 1 Homo sapiens 79-85 25829763-7 2015 Further, the ability of ES to inhibit multi drug resistant (MDR) transporters (ABC-B1 and ABC-G2) was determined by Rhodamine (Rho) and Mitoxantrone (MXR) efflux assays. Rhodamines 116-119 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 90-96 25666715-1 2015 Two new rhodamine derivatives (L1 and L2) were synthesized, characterized and their ion recognition property has been investigated. Rhodamines 8-17 L1 cell adhesion molecule Homo sapiens 31-40 25730814-0 2015 Rhodamine-123: a p-glycoprotein marker complex with sodium lauryl sulfate. Rhodamines 0-9 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 17-31 25765837-7 2015 The lignans can increase the retention of the P-gp substrate rhodamine 123 in CEM/ADR 5000 cells, indicating that lignans can inhibit the activity of P-gp. Rhodamines 61-70 phosphoglycolate phosphatase Homo sapiens 150-154 25686090-6 2015 In addition, multicopies of SNQ2 or PDR5 conferred resistance to rhodamine 6G (R6G), which was widely used as a substrate for transport assay. Rhodamines 65-74 ATP-binding cassette transporter SNQ2 Saccharomyces cerevisiae S288C 28-32 25676275-4 2015 The expression of P-gp was detected by cell immunofluorescense analysis and the activity of P-gp was evaluated by Rhodamine 123 efflux experiment. Rhodamines 114-123 ATP binding cassette subfamily B member 1 Homo sapiens 92-96 25445037-8 2015 Most DHPs, particularly compounds bearing 3-nitrophenyl (A2B2 and A3B2) and 4-nitrophenyl (A3B1 and A4B1) moieties at C4 significantly inhibited rhodamine 123 efflux at 5-25 microM, showing that the mechanism of MDR reversal by these agents is P-gp transporter modulation. Rhodamines 145-154 ATP binding cassette subfamily B member 1 Homo sapiens 244-248 25470220-4 2015 Compound 7 h also enhanced the effects of other MDR-related cytotoxic agents (paclitaxel, vinblastine, and daunorubicin), increased the accumulation of DOX and blocked P-gp-mediated rhodamine 123 efflux function in K562/A02 MDR cells. Rhodamines 182-191 ATP binding cassette subfamily B member 1 Homo sapiens 168-172 25510469-7 2015 When a CaF2/ZnS DBR was grown, without heating the substrate during deposition, on top of a thin film containing the fluorescent dye Rhodamine 6G, the fluorescence intensity showed no degradation compared to an uncoated film, in contrast to a MgF2/ZnS DBR coating grown with substrate heating which showed a 92% reduction in signal. Rhodamines 133-142 CCR4-NOT transcription complex subunit 8 Homo sapiens 7-11 25686090-6 2015 In addition, multicopies of SNQ2 or PDR5 conferred resistance to rhodamine 6G (R6G), which was widely used as a substrate for transport assay. Rhodamines 65-74 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 36-40 26046259-8 2015 Methyl-G increased the intracellular concentration of a known Pgp substrate, Rhodamine 123 in SF-295 cells. Rhodamines 77-86 ATP binding cassette subfamily B member 1 Homo sapiens 62-65 25403403-3 2014 On the other hand, the fluorescence distribution plot showed predominant location of CD133(+) cancer cells among cells stained with neither DyeCycle Violet DNA-binding dye, nor rhodamine 123 mitochondrial dye. Rhodamines 177-186 prominin 1 Homo sapiens 85-90 25433164-11 2015 Functionality of P-gp assessed with Rhodamine permeability did not change with passage number in Caco-2 cells with any of the protocols but increased in both protocols in MDCK and MDCK-MDR1 cells. Rhodamines 36-45 phosphoglycolate phosphatase Homo sapiens 17-21 25545265-1 2014 The reagent Rh-C, incorporating a rhodamine moiety and a coumarin backbone and prepared via click chemistry, was developed as the first single molecule for detecting Cu2+, Fe3+ and Cr3+. Rhodamines 34-43 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 181-184 26088979-5 2014 The 3D-NPG nanostructures were found to effectively enhance the SERS sensitivity of rhodamine 6G (R6G) molecules with a concentration up to 10(-8) M. Rhodamines 84-93 seryl-tRNA synthetase 1 Homo sapiens 64-68 25372840-9 2014 The intracellular level of ATP decreased 44%, 46% in the presence of 12.5.25 microM 3-Bromopyruvate, whereas the accumulation of rhodamine 123 and epirubicin (two typical P-glycoprotein substrates) in cells was significantly increased. Rhodamines 129-138 ATP binding cassette subfamily B member 1 Homo sapiens 171-185 25189757-8 2014 The CNF surface bound AgNPs were easily fabricated into freestanding CNF/AgNPs films that showed excellent surface enhanced Raman scattering of Rhodamine 6G with analytical enhancement factor of 5 x 10(3) in contrast to none from the CNF/AgNSs film. Rhodamines 144-153 NPHS1 adhesion molecule, nephrin Homo sapiens 4-7 24734954-5 2014 MDR-1 function was assessed by Rhodamine efflux in presence or absence of verapamil. Rhodamines 31-40 ATP binding cassette subfamily B member 1 Homo sapiens 0-5 25189757-8 2014 The CNF surface bound AgNPs were easily fabricated into freestanding CNF/AgNPs films that showed excellent surface enhanced Raman scattering of Rhodamine 6G with analytical enhancement factor of 5 x 10(3) in contrast to none from the CNF/AgNSs film. Rhodamines 144-153 NPHS1 adhesion molecule, nephrin Homo sapiens 69-72 25189757-8 2014 The CNF surface bound AgNPs were easily fabricated into freestanding CNF/AgNPs films that showed excellent surface enhanced Raman scattering of Rhodamine 6G with analytical enhancement factor of 5 x 10(3) in contrast to none from the CNF/AgNSs film. Rhodamines 144-153 NPHS1 adhesion molecule, nephrin Homo sapiens 69-72 25478314-0 2014 Rhodamine-Appended Bipyridine: XOR and OR Logic Operations Integrated in an Example of Controlled Metal Migration. Rhodamines 0-9 xanthine dehydrogenase Homo sapiens 31-34 25050613-0 2014 Synthesis and characterization of macromolecular rhodamine tethers and their interactions with P-glycoprotein. Rhodamines 49-58 ATP binding cassette subfamily B member 1 Homo sapiens 95-109 24814693-6 2014 DAPK3 siRNA or a pharmacological inhibitor of DAPK3 inhibited PDGF-BB-induced lamellipodia formation as determined by rhodamine-phalloidin staining. Rhodamines 118-127 death-associated protein kinase 3 Rattus norvegicus 0-5 24814693-6 2014 DAPK3 siRNA or a pharmacological inhibitor of DAPK3 inhibited PDGF-BB-induced lamellipodia formation as determined by rhodamine-phalloidin staining. Rhodamines 118-127 death-associated protein kinase 3 Rattus norvegicus 46-51 25108566-5 2014 RESULTS: Both fAd and gAd increased RhoA activity, phosphorylation of the Rho/ROCK signaling target cofilin and actin polymerization to form filamentous actin as determined by rhodamine-phallodin immunofluorescence and quantitative analysis of filamentous to globular actin ratio. Rhodamines 176-185 presenilin 1 Homo sapiens 14-17 25108566-5 2014 RESULTS: Both fAd and gAd increased RhoA activity, phosphorylation of the Rho/ROCK signaling target cofilin and actin polymerization to form filamentous actin as determined by rhodamine-phallodin immunofluorescence and quantitative analysis of filamentous to globular actin ratio. Rhodamines 176-185 glutamate decarboxylase 1 Homo sapiens 22-25 25166911-3 2014 The entrapped cargo of rhodamine 6G was shown to be selectively released from PoPs upon exposure to divalent cations including the alpha-synuclein-specific pathophysiological ligand of Ca(2+). Rhodamines 23-32 synuclein alpha Homo sapiens 131-146 24967548-6 2014 In addition, p53 protein inexpression, mediated by rhodamine nanoparticles, demonstrates the ability of the proposed system to target mitochondria; due to the different genetic code in mitochondria, p53 protein cannot be expressed. Rhodamines 51-60 tumor protein p53 Homo sapiens 13-16 25050613-1 2014 Rhodamine dyes are well-known P-glycoprotein (P-gp) substrates that have played an important role in the detection of inhibitors and other substrates of P-gp, as well as in the understanding of P-gp function. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 30-44 25050613-1 2014 Rhodamine dyes are well-known P-glycoprotein (P-gp) substrates that have played an important role in the detection of inhibitors and other substrates of P-gp, as well as in the understanding of P-gp function. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 46-50 25050613-1 2014 Rhodamine dyes are well-known P-glycoprotein (P-gp) substrates that have played an important role in the detection of inhibitors and other substrates of P-gp, as well as in the understanding of P-gp function. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 153-157 25050613-1 2014 Rhodamine dyes are well-known P-glycoprotein (P-gp) substrates that have played an important role in the detection of inhibitors and other substrates of P-gp, as well as in the understanding of P-gp function. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 153-157 25050613-2 2014 Macromolecular conjugates of rhodamines could prove useful as tethers for further probing of P-gp structure and function. Rhodamines 29-39 ATP binding cassette subfamily B member 1 Homo sapiens 93-97 25121365-6 2014 P-gp activity was measured by flow cytometry using rhodamine efflux. Rhodamines 51-60 phosphoglycolate phosphatase Homo sapiens 0-4 24704556-6 2014 Furthermore, it could also increase the retention of ABCB1 substrates doxorubicin and rhodamine 123 in HepG2/ADM and MCF-7/ADR cells. Rhodamines 86-95 ATP binding cassette subfamily B member 1 Homo sapiens 53-58 24704556-6 2014 Furthermore, it could also increase the retention of ABCB1 substrates doxorubicin and rhodamine 123 in HepG2/ADM and MCF-7/ADR cells. Rhodamines 86-95 adrenomedullin Homo sapiens 109-112 26420981-6 2014 rhodamine-labelled PBCA NP variations into rats and monitored the survival and morphology of retrogradely labelled neurons by in vivo confocal neuroimaging (ICON) for five weeks. Rhodamines 0-9 PBCA Homo sapiens 19-23 24512977-7 2014 Based on these profiles, gelatin and PLGA NPs were used to encapsulate plasmid DNA encoding yellow fluorescent protein (YFP) or rhodamine-conjugated erythropoietin (EPO) for inhalational delivery to rats. Rhodamines 128-137 erythropoietin Rattus norvegicus 149-163 24512977-7 2014 Based on these profiles, gelatin and PLGA NPs were used to encapsulate plasmid DNA encoding yellow fluorescent protein (YFP) or rhodamine-conjugated erythropoietin (EPO) for inhalational delivery to rats. Rhodamines 128-137 erythropoietin Rattus norvegicus 165-168 24738437-6 2014 The as-synthesized ANAs array exhibited a remarkable SERS activity and Raman signal reproducibility to rhodamine 6G, a concentration down to 10(-13) M can be identified. Rhodamines 103-112 seryl-tRNA synthetase 1 Homo sapiens 53-57 24948896-2 2014 LFP has been widely used as an electrode material of a lithium ion battery, but we observed that commercial LFP (LFP-C) could act as a good Fenton-like catalyst to decompose rhodamine 6G. Rhodamines 174-183 lamin A/C Homo sapiens 0-3 24733388-5 2014 The completely "regenerated" Pdr5 protein was severely impaired in its function of ATP hydrolysis and of rhodamine 6G transport. Rhodamines 105-114 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 29-33 24948896-2 2014 LFP has been widely used as an electrode material of a lithium ion battery, but we observed that commercial LFP (LFP-C) could act as a good Fenton-like catalyst to decompose rhodamine 6G. Rhodamines 174-183 lamin A/C Homo sapiens 108-111 24948896-2 2014 LFP has been widely used as an electrode material of a lithium ion battery, but we observed that commercial LFP (LFP-C) could act as a good Fenton-like catalyst to decompose rhodamine 6G. Rhodamines 174-183 lamin A/C Homo sapiens 113-118 24944746-1 2014 Novel rhodamine-labeled ligands, based on (S)-citalopram, were synthesized and evaluated for uptake inhibition at the human serotonin, dopamine, and norepinephrine transporters (hSERT, hDAT, and hNET, respectively) and for binding at SERT, in transiently transfected COS7 cells. Rhodamines 6-15 solute carrier family 6 member 4 Homo sapiens 179-183 24805805-4 2014 The performance of S-SERS is evaluated by the detection of Rhodamine 6G, urea, and its mixture with acetaminophen, in a physiologically relevant concentration range, along with the corresponding SERS spectroscopic maps. Rhodamines 59-68 seryl-tRNA synthetase 1 Homo sapiens 21-25 24558643-1 2014 The effect of substituents on FRET in two newly designed rhodamine-based Hg(2+) ion selective chemosensors (L1 and L2) has been explored by a systematic experimental and theoretical study. Rhodamines 57-66 L1 cell adhesion molecule Homo sapiens 108-117 24735764-13 2014 CONCLUSIONS: This study showed reduced function of P-glycoprotein in ischemia-reperfusion injury as reflected by decreased biliary excretion of Rhodamine 123, as well as reduced protein expression of the transporter. Rhodamines 144-153 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 51-65 24602286-12 2014 In addition, intracellular accumulation of Rhodamine 123 significantly increased in MCF-7/ADR cells transfected with ETS1 siRNA, indicating that silencing of ETS1 may reduce drug efflux. Rhodamines 43-52 ETS proto-oncogene 1, transcription factor Homo sapiens 117-121 24602286-12 2014 In addition, intracellular accumulation of Rhodamine 123 significantly increased in MCF-7/ADR cells transfected with ETS1 siRNA, indicating that silencing of ETS1 may reduce drug efflux. Rhodamines 43-52 ETS proto-oncogene 1, transcription factor Homo sapiens 158-162 24493631-6 2014 In situ intestinal perfusion experiments also showed that CK, Ppd, and Ppt increased the absorption rate constant and permeability coefficient of rhodamine 123. Rhodamines 146-155 tachykinin precursor 1 Homo sapiens 71-74 22913740-0 2014 The mitochondrial fluorescent dye rhodamine 123 is a high-affinity substrate for organic cation transporters (OCTs) 1 and 2. Rhodamines 34-43 solute carrier family 22 member 1 Homo sapiens 81-123 22913740-4 2014 This increase of rhodamine 123 influxes was found to be a saturable carrier-mediated process, with low K(m) values (K(m) = 0.54 mum and K(m) = 0.61 mum for transport of the dye in hOCT1- and hOCT2-positive HEK293 cells, respectively). Rhodamines 17-26 solute carrier family 22 member 1 Homo sapiens 180-185 22913740-4 2014 This increase of rhodamine 123 influxes was found to be a saturable carrier-mediated process, with low K(m) values (K(m) = 0.54 mum and K(m) = 0.61 mum for transport of the dye in hOCT1- and hOCT2-positive HEK293 cells, respectively). Rhodamines 17-26 solute carrier family 22 member 2 Homo sapiens 191-196 23728918-0 2014 Rhodamine-marked bombesin: a novel means for prostate cancer fluorescence imaging. Rhodamines 0-9 gastrin releasing peptide Homo sapiens 17-25 23728918-4 2014 These novel rhodamine fluorescent conjugates were used to study the targeting and uptake of bombesin on a cellular level. Rhodamines 12-21 gastrin releasing peptide Homo sapiens 92-100 24621983-5 2014 The impact of the 1199G>A SNP on ABCB1 activity towards rhodamine (Rh123), doxorubicin, vinblastine, tacrolimus and cyclosporine A was assessed by accumulation, cytotoxicity and/or kinetic experiments. Rhodamines 59-68 ATP binding cassette subfamily B member 1 Homo sapiens 36-41 24504599-1 2014 In this work, we investigated Greek Leishmania isolates (n = 70) for their individual MDR1-gene-related p-gp (belonging to the ABC-B subfamily of permeases) expression levels by means of flow cytometric analysis of Rhodamine 123 extrusion kinetics. Rhodamines 215-224 ATP binding cassette subfamily B member 1 Homo sapiens 86-90 32261280-0 2014 Self-focusing Au@SiO2 nanorods with rhodamine 6G as highly sensitive SERS substrate for carcinoembryonic antigen detection. Rhodamines 36-45 CEA cell adhesion molecule 3 Homo sapiens 88-112 24471913-2 2014 The rhodamine-labeled C-peptide entered renal tubular cells and localized in nuclei, both in the presence and absence of insulin; preincubations with the unlabeled compound inhibited internalization. Rhodamines 4-13 insulin Oryctolagus cuniculus 121-128 22913740-6 2014 In addition, the dye was found to inhibit hOCT1- and hOCT2-mediated uptake of tetraethylammonium (TEA), a model substrate for both hOCT1 and hOCT2; rhodamine 123 appeared nevertheless to be a more potent inhibitor of hOCT1-mediated TEA transport (IC50 = 0.37 mum) than of that mediated by hOCT2 (IC50 = 61.5 mum). Rhodamines 148-157 solute carrier family 22 member 1 Homo sapiens 42-47 22913740-6 2014 In addition, the dye was found to inhibit hOCT1- and hOCT2-mediated uptake of tetraethylammonium (TEA), a model substrate for both hOCT1 and hOCT2; rhodamine 123 appeared nevertheless to be a more potent inhibitor of hOCT1-mediated TEA transport (IC50 = 0.37 mum) than of that mediated by hOCT2 (IC50 = 61.5 mum). Rhodamines 148-157 solute carrier family 22 member 2 Homo sapiens 53-58 22913740-6 2014 In addition, the dye was found to inhibit hOCT1- and hOCT2-mediated uptake of tetraethylammonium (TEA), a model substrate for both hOCT1 and hOCT2; rhodamine 123 appeared nevertheless to be a more potent inhibitor of hOCT1-mediated TEA transport (IC50 = 0.37 mum) than of that mediated by hOCT2 (IC50 = 61.5 mum). Rhodamines 148-157 solute carrier family 22 member 1 Homo sapiens 131-136 22913740-6 2014 In addition, the dye was found to inhibit hOCT1- and hOCT2-mediated uptake of tetraethylammonium (TEA), a model substrate for both hOCT1 and hOCT2; rhodamine 123 appeared nevertheless to be a more potent inhibitor of hOCT1-mediated TEA transport (IC50 = 0.37 mum) than of that mediated by hOCT2 (IC50 = 61.5 mum). Rhodamines 148-157 solute carrier family 22 member 2 Homo sapiens 141-146 22913740-6 2014 In addition, the dye was found to inhibit hOCT1- and hOCT2-mediated uptake of tetraethylammonium (TEA), a model substrate for both hOCT1 and hOCT2; rhodamine 123 appeared nevertheless to be a more potent inhibitor of hOCT1-mediated TEA transport (IC50 = 0.37 mum) than of that mediated by hOCT2 (IC50 = 61.5 mum). Rhodamines 148-157 solute carrier family 22 member 1 Homo sapiens 131-136 22913740-6 2014 In addition, the dye was found to inhibit hOCT1- and hOCT2-mediated uptake of tetraethylammonium (TEA), a model substrate for both hOCT1 and hOCT2; rhodamine 123 appeared nevertheless to be a more potent inhibitor of hOCT1-mediated TEA transport (IC50 = 0.37 mum) than of that mediated by hOCT2 (IC50 = 61.5 mum). Rhodamines 148-157 solute carrier family 22 member 2 Homo sapiens 141-146 22913740-7 2014 Taken together, these data demonstrate that rhodamine 123 is a high-affinity substrate for both hOCT1 and hOCT2. Rhodamines 44-53 solute carrier family 22 member 1 Homo sapiens 96-101 22913740-7 2014 Taken together, these data demonstrate that rhodamine 123 is a high-affinity substrate for both hOCT1 and hOCT2. Rhodamines 44-53 solute carrier family 22 member 2 Homo sapiens 106-111 24117322-5 2013 The results demonstrate that a maximum enhancement factor can reach ~10(5) with a detectable concentration as low as 10(-10) M for rhodamine 6G (R6G) molecules, indicating that the as-obtained unique nanostructure will be a promising candidate for SERS applications. Rhodamines 131-140 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 248-252 24130053-6 2013 Here, using a ubiquitin-rhodamine-based high-throughput screening, we identified small-molecule inhibitors of USP1 and investigated their therapeutic potential for leukemia. Rhodamines 24-33 ubiquitin specific peptidase 1 Homo sapiens 110-114 24107183-2 2013 Here we describe a nanosensor for caspase-1 ratiometric measurements, consisting of a rhodamine-labeled, caspase-1 cleavable peptide linked to quantum dots (QDs). Rhodamines 86-95 caspase 1 Homo sapiens 34-43 24107183-2 2013 Here we describe a nanosensor for caspase-1 ratiometric measurements, consisting of a rhodamine-labeled, caspase-1 cleavable peptide linked to quantum dots (QDs). Rhodamines 86-95 caspase 1 Homo sapiens 105-114 24237849-5 2013 ABPP was performed by reacting urines (n = 18) with a rhodamine-tagged fluorophosphonate probe and visualizing on SDS-PAGE. Rhodamines 54-63 amyloid beta precursor protein Homo sapiens 0-4 24036383-0 2013 Rhodamine-loaded intercellular adhesion molecule-1-targeted microbubbles for dual-modality imaging under controlled shear stresses. Rhodamines 0-9 intercellular adhesion molecule 1 Homo sapiens 17-50 23872169-3 2013 METHODS: The signal transduction pathway of PI3-K/AKT and the downstream signaling proteins had been studied in an early stage of colon carcinogenesis (DMH induced) by gene and protein expression, apoptotic studies by colonocyte apoptotic bleb assay, intracellular calcium level by fluorescence spectrometry, mitochondrial membrane potential by Rhodamine 123 flow cytometry and Reactive oxygen species measurement. Rhodamines 345-354 AKT serine/threonine kinase 1 Rattus norvegicus 50-53 24036383-3 2013 METHODS AND RESULTS: Using 2-photon laser scanning microscopy and contrast-enhanced ultrasound, intercellular adhesion molecule-1-targeted and rhodamine-loaded microbubbles were shown to be specifically bound to tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells and murine carotid arteries (44 wild-type mice) at shear stresses ranging from 1.25 to 120 dyn/cm(2). Rhodamines 143-152 tumor necrosis factor Homo sapiens 212-239 24041929-4 2013 rhodamine 123 acts as a good substrate for P-glycoprotein, and agents that block P-glycoprotein have been found to increase the retention of rhodamine in cells. Rhodamines 0-9 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 43-57 24041929-4 2013 rhodamine 123 acts as a good substrate for P-glycoprotein, and agents that block P-glycoprotein have been found to increase the retention of rhodamine in cells. Rhodamines 141-150 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 81-95 23271055-5 2013 Tau synergized with Hsc70, but not Hsp72, to promote microtubule assembly at nearly twice the rate of either Hsp70 homologue in reconstituted, ATP-regenerating Xenopus extracts supplemented with rhodamine-labeled tubulin and human recombinant Hsp72 and Hsc70. Rhodamines 195-204 microtubule associated protein tau Homo sapiens 0-3 23897240-4 2013 In everted intestinal sacs, AP inhibited serosal-mucosal transport of rhodamine 123 (R123), a prototypical P-gp substrate. Rhodamines 70-79 ATP binding cassette subfamily B member 1 Homo sapiens 107-111 23897419-1 2013 Venlafaxine, and to a lesser extent desvenlafaxine, has previously been shown to induce the expression of the drug efflux transporters P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) in whole cells and alter the cellular permeability of a known drug efflux probe (rhodamine 123). Rhodamines 282-291 phosphoglycolate phosphatase Mus musculus 135-149 23897419-1 2013 Venlafaxine, and to a lesser extent desvenlafaxine, has previously been shown to induce the expression of the drug efflux transporters P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) in whole cells and alter the cellular permeability of a known drug efflux probe (rhodamine 123). Rhodamines 282-291 phosphoglycolate phosphatase Mus musculus 151-155 23897419-1 2013 Venlafaxine, and to a lesser extent desvenlafaxine, has previously been shown to induce the expression of the drug efflux transporters P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) in whole cells and alter the cellular permeability of a known drug efflux probe (rhodamine 123). Rhodamines 282-291 ATP binding cassette subfamily G member 2 (Junior blood group) Mus musculus 161-193 23897419-1 2013 Venlafaxine, and to a lesser extent desvenlafaxine, has previously been shown to induce the expression of the drug efflux transporters P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) in whole cells and alter the cellular permeability of a known drug efflux probe (rhodamine 123). Rhodamines 282-291 ATP binding cassette subfamily G member 2 (Junior blood group) Mus musculus 195-199 23608541-3 2013 The quenching intensity of the fluorescence images for rhodamine-labeled ssDNA fitted well with the changes in SPR. Rhodamines 55-64 sepiapterin reductase Homo sapiens 111-114 23380148-1 2013 A novel FRET fluorescent sensor for Hg2+ imaging in living cells is rationally designed based on a coumarin-rhodamine platform. Rhodamines 108-117 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 36-39 23380148-3 2013 After addition of increasing concentrations of Hg2+, it result in the decrease of coumarin emission at 467 nm and a new emission profile of rhodamine at 590 nm gradually increased. Rhodamines 140-149 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 47-50 23524533-4 2013 P-gp expression was determined by western blot and activity determined by rhodamine efflux assay. Rhodamines 74-83 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 23618585-9 2013 After 30 minutes of efflux, rhodamine 123 fluorescence intensity was significantly lower in BIU-87/ADM cells (5.55 vs 51.45, p = 0.004) and co-cultured BIU-87 cells than in BIU-87 cells (14.22 vs 51.45, p <0.001), indicating that P-glycoprotein was functional. Rhodamines 28-37 ATP binding cassette subfamily B member 1 Homo sapiens 233-247 23594094-5 2013 Confocal microscopy confirmed the Tf receptor-mediated endocytosis of rhodamine-labeled Tf-modified micelles after staining the micelle-treated cells with the endosomal marker Tf-Alexa488. Rhodamines 70-79 transferrin Homo sapiens 34-36 23594094-5 2013 Confocal microscopy confirmed the Tf receptor-mediated endocytosis of rhodamine-labeled Tf-modified micelles after staining the micelle-treated cells with the endosomal marker Tf-Alexa488. Rhodamines 70-79 transferrin Homo sapiens 88-90 23743668-5 2013 METHODS: Rhodamine (Rh123) efflux was used to study ABCB1 activity, with or without the addition of the ABCB1 inhibitor verapamil. Rhodamines 9-18 ATP binding cassette subfamily B member 1 Homo sapiens 52-57 23705772-1 2013 A series of deep red fluorescent dyes (CR1 to CR3) was developed via introduction of a coumarin moiety into the rhodamine molecular skeleton. Rhodamines 112-121 complement C3b/C4b receptor 1 (Knops blood group) Homo sapiens 39-42 23705772-1 2013 A series of deep red fluorescent dyes (CR1 to CR3) was developed via introduction of a coumarin moiety into the rhodamine molecular skeleton. Rhodamines 112-121 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 46-49 23799018-6 2013 In turn, apelin 14 was conjugated to rhodamine-encapsulating liposomes and administered to tumor-bearing mice. Rhodamines 37-46 apelin Mus musculus 9-15 23468132-8 2013 In addition, ABCB1 and ABCB4 mediated the efflux of rhodamine 123 and rhodamine 6G from nonraft membranes, which was not affected by taurocholate. Rhodamines 52-61 ATP binding cassette subfamily B member 1 Homo sapiens 13-18 23468132-8 2013 In addition, ABCB1 and ABCB4 mediated the efflux of rhodamine 123 and rhodamine 6G from nonraft membranes, which was not affected by taurocholate. Rhodamines 52-61 ATP binding cassette subfamily B member 4 Homo sapiens 23-28 23457297-6 2013 The direct interaction of BmCrzR with BmCrz was confirmed by a rhodamine-labeled BmCrz peptide. Rhodamines 63-72 neuropeptide receptor A21 Bombyx mori 26-32 23457297-6 2013 The direct interaction of BmCrzR with BmCrz was confirmed by a rhodamine-labeled BmCrz peptide. Rhodamines 63-72 pro-corazonin Bombyx mori 26-31 23457297-6 2013 The direct interaction of BmCrzR with BmCrz was confirmed by a rhodamine-labeled BmCrz peptide. Rhodamines 63-72 pro-corazonin Bombyx mori 38-43 23423264-0 2013 A rhodamine derivative as a "lock" and SCN- as a "key": visible light excitable SCN- sensing in living cells. Rhodamines 2-11 sorcin Homo sapiens 80-83 23423264-1 2013 A visible light excitable rhodamine based probe operates as a SCN(-) selective fluorescent "turn-on" sensor for living cell imaging with a detection limit of 0.01 muM, which is much lower than the normal SCN(-) level in the human body. Rhodamines 26-35 sorcin Homo sapiens 62-65 23423264-1 2013 A visible light excitable rhodamine based probe operates as a SCN(-) selective fluorescent "turn-on" sensor for living cell imaging with a detection limit of 0.01 muM, which is much lower than the normal SCN(-) level in the human body. Rhodamines 26-35 latexin Homo sapiens 163-166 23423264-1 2013 A visible light excitable rhodamine based probe operates as a SCN(-) selective fluorescent "turn-on" sensor for living cell imaging with a detection limit of 0.01 muM, which is much lower than the normal SCN(-) level in the human body. Rhodamines 26-35 sorcin Homo sapiens 204-207 23423264-2 2013 A "lock" and "key" model has been proposed to explain the fluorescence enhancement of the rhodamine probe in the presence of SCN(-). Rhodamines 90-99 sorcin Homo sapiens 125-128 23528086-2 2013 We used high-speed polarized total internal reflection fluorescence (polTIRF) microscopy to study the structural dynamics of single myosin V molecules that had been labeled with bifunctional rhodamine linked to one of the calmodulins along the lever arm. Rhodamines 191-200 myosin VA Homo sapiens 132-140 23507591-4 2013 For example, gGlu-HMRG, a novel spirocyclized rhodamine-based fluorescence probe for gamma-glutamyltranspeptidase(GGT), which is well-known to be upregulated in various cancer cells, was successfully developed. Rhodamines 46-55 gamma-glutamyltransferase light chain 5 pseudogene Homo sapiens 85-118 23356389-4 2013 For Pdr5, five compounds could be identified that inhibited rhodamine 6G transport more efficiently than zosuquidar. Rhodamines 60-69 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 4-8 23356389-6 2013 Furthermore, the determination of IC(50) values for rhodamine 6G transport of Pdr5 with representative compounds reveals values between 0.3 and 0.9 muM. Rhodamines 52-61 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 78-82 23393332-2 2013 A fluorescent probe for detecting HER2/neu-expressing cells was generated by conjugation of the humanized anti-HER2/neu antibody trastuzumab with rhodamine. Rhodamines 146-155 erb-b2 receptor tyrosine kinase 2 Mus musculus 34-38 23393332-2 2013 A fluorescent probe for detecting HER2/neu-expressing cells was generated by conjugation of the humanized anti-HER2/neu antibody trastuzumab with rhodamine. Rhodamines 146-155 erb-b2 receptor tyrosine kinase 2 Mus musculus 39-42 23393332-2 2013 A fluorescent probe for detecting HER2/neu-expressing cells was generated by conjugation of the humanized anti-HER2/neu antibody trastuzumab with rhodamine. Rhodamines 146-155 erb-b2 receptor tyrosine kinase 2 Mus musculus 111-115 23393332-2 2013 A fluorescent probe for detecting HER2/neu-expressing cells was generated by conjugation of the humanized anti-HER2/neu antibody trastuzumab with rhodamine. Rhodamines 146-155 erb-b2 receptor tyrosine kinase 2 Mus musculus 116-119 23393332-4 2013 All tumor-bearing mice were given a single intravenous injection of either rhodamine-conjugated anti-HER2/neu probe, or conjugated control IgG antibody, when LN metastasis developed. Rhodamines 75-84 erb-b2 receptor tyrosine kinase 2 Mus musculus 101-105 23393332-4 2013 All tumor-bearing mice were given a single intravenous injection of either rhodamine-conjugated anti-HER2/neu probe, or conjugated control IgG antibody, when LN metastasis developed. Rhodamines 75-84 erb-b2 receptor tyrosine kinase 2 Mus musculus 106-109 23393332-5 2013 Each animal was imaged with both green and red fluorescence to assess in vivo binding of the rhodamine-conjugated anti-HER2/neu probe to the tumors and LN metastases. Rhodamines 93-102 erb-b2 receptor tyrosine kinase 2 Mus musculus 119-123 23393332-5 2013 Each animal was imaged with both green and red fluorescence to assess in vivo binding of the rhodamine-conjugated anti-HER2/neu probe to the tumors and LN metastases. Rhodamines 93-102 erb-b2 receptor tyrosine kinase 2 Mus musculus 124-127 23393332-8 2013 The primary tumors and LN metastases from the animals which were treated with rhodamine-conjugated anti-HER2/neu probe exhibited a visible red fluorescence signal. Rhodamines 78-87 erb-b2 receptor tyrosine kinase 2 Mus musculus 104-108 23393332-8 2013 The primary tumors and LN metastases from the animals which were treated with rhodamine-conjugated anti-HER2/neu probe exhibited a visible red fluorescence signal. Rhodamines 78-87 erb-b2 receptor tyrosine kinase 2 Mus musculus 109-112 23393332-10 2013 Sensitivity of 78% (14 out of 18) and specificity of 100% (20 out of 20) could be achieved with the rhodamine-conjugated anti-HER2/neu probe for the detection of LN metastasis. Rhodamines 100-109 erb-b2 receptor tyrosine kinase 2 Mus musculus 126-130 23393332-10 2013 Sensitivity of 78% (14 out of 18) and specificity of 100% (20 out of 20) could be achieved with the rhodamine-conjugated anti-HER2/neu probe for the detection of LN metastasis. Rhodamines 100-109 erb-b2 receptor tyrosine kinase 2 Mus musculus 131-134 23172365-8 2013 Finally, the water soluble azide-reactive phosphine probe, rho-TEO-phosphine (21) (rho: rhodamine), has been designed and applied to attach a chromophore to azido-(K1)RNase A via Staudinger ligation at physiological pH indicating that the introduced azido group is accessible and could be addressed by other established azide-reactive bioorthogonal reaction schemes. Rhodamines 88-97 ribonuclease A family member 1, pancreatic Homo sapiens 167-174 23166305-9 2013 The downregulation of miR-145 in Caco-2 cells, an epithelial cell line derived from human colon, increased P-gp expression and efflux activity of rhodamine 123, but not MDR1 mRNA level. Rhodamines 146-155 microRNA 145 Homo sapiens 22-29 23216707-6 2013 Pgp activity was evaluated in PBMC using the Rhodamine 123 efflux assay. Rhodamines 45-54 ATP binding cassette subfamily B member 1 Homo sapiens 0-3 23302031-1 2013 We have synthesized a new indole functionalized rhodamine derivative L(1) which specifically binds to Cu(2+) in the presence of large excess of other competing ions with visually observable changes in their electronic and fluorescence spectral behavior. Rhodamines 48-57 immunoglobulin kappa variable 1-16 Homo sapiens 69-73 23035695-5 2012 Concomitantly, P-gp protein expression increased 2.5-fold and was accompanied by a 20-35% reduction in cellular accumulation of the P-gp substrates, rhodamine 6G (R6G), and HiLyte Fluor 488-labeled human amyloid beta 1-42 (hAbeta(42)). Rhodamines 149-158 phosphoglycolate phosphatase Homo sapiens 15-19 24025574-0 2013 A fluorescent chemosensor for Hg2+ based on a rhodamine derivative in an aqueous solution. Rhodamines 46-55 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 30-33 23168018-0 2013 A rhodamine-labeled citalopram analogue as a high-affinity fluorescent probe for the serotonin transporter. Rhodamines 2-11 solute carrier family 6 member 4 Homo sapiens 85-106 23168018-3 2013 The resulting rhodamine-labeled ligand 8 inhibited [(3)H]5-HT uptake in COS-7 cells (K(i)=225 nM) with similar potency to the tropane-based JHC 1-064 (1), but with higher specificity towards the SERT relative to the transporters for dopamine and norepinephrine. Rhodamines 14-23 solute carrier family 6 member 4 Homo sapiens 195-199 23646714-4 2013 In addition, scFV-SCLs (effective diameter: 185.7 nm; polydispersity index: 0.236) can significantly boost rhodamine 123 cellular accumulation in the cytoplasm. Rhodamines 107-116 immunglobulin heavy chain variable region Homo sapiens 13-17 23234641-4 2013 Here we validate the new dye-probe beta-amyloid (1-40) HiLyte Fluor TR-labeled (Ab-HiLyte) (Anaspec) P-gp mediated transport in the ex vivo rat everted gut sac assay by using MC18 or MC266, a fully characterized P-gp inhibitor and substrate, respectively, and compare it with the commonly used dye rhodamine. Rhodamines 299-308 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 102-106 23234641-4 2013 Here we validate the new dye-probe beta-amyloid (1-40) HiLyte Fluor TR-labeled (Ab-HiLyte) (Anaspec) P-gp mediated transport in the ex vivo rat everted gut sac assay by using MC18 or MC266, a fully characterized P-gp inhibitor and substrate, respectively, and compare it with the commonly used dye rhodamine. Rhodamines 299-308 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 213-217 23150440-2 2013 Here, we describe a detailed protocol to identify small molecules capable of targeting p53-MDM2/MDMX interactions using a fluorescence polarization assay with Rhodamine-labeled p53 peptides. Rhodamines 159-168 tumor protein p53 Homo sapiens 87-90 23150440-2 2013 Here, we describe a detailed protocol to identify small molecules capable of targeting p53-MDM2/MDMX interactions using a fluorescence polarization assay with Rhodamine-labeled p53 peptides. Rhodamines 159-168 MDM2 proto-oncogene Homo sapiens 91-95 23150440-2 2013 Here, we describe a detailed protocol to identify small molecules capable of targeting p53-MDM2/MDMX interactions using a fluorescence polarization assay with Rhodamine-labeled p53 peptides. Rhodamines 159-168 MDM4 regulator of p53 Homo sapiens 96-100 23150440-2 2013 Here, we describe a detailed protocol to identify small molecules capable of targeting p53-MDM2/MDMX interactions using a fluorescence polarization assay with Rhodamine-labeled p53 peptides. Rhodamines 159-168 tumor protein p53 Homo sapiens 177-180 23144078-10 2013 Using rhodamine-labeled NP and U251 glioma cell-derived xenografts, we demonstrated that the NP-TRAIL were found in the tumor site and induced a significant increase in glioma cell apoptosis, a decrease in tumor volume, and increased animal survival. Rhodamines 6-15 TNF superfamily member 10 Homo sapiens 96-101 22695925-1 2012 A novel rhodamine derivative (Rh-C), synthesized by the reaction of rhodamine ethylenediamine and cinnamoyl chloride, was evaluated as a chemoselective Hg(2+) ion sensor. Rhodamines 8-17 HCL2 Homo sapiens 30-34 22965487-2 2012 METHODS AND RESULTS: Rhodamine absorption displayed saturation kinetics with a K(m) of 1.1 muM and a pH-optimum of 8.5 and was stimulated by flavone four-fold in its V(max) . Rhodamines 21-30 latexin Homo sapiens 92-95 22981987-8 2012 Half-maximum effect concentrations (IC(50)) for inhibition of Pgp-mediated rhodamine 123 efflux from CCRFvcr1000 cells were 375+-60nM for MC113 versus 8.5+-2.5nM for tariquidar. Rhodamines 75-84 phosphoglycolate phosphatase Mus musculus 62-65 22932925-0 2012 FRET-based ratiometric detection of Hg2+ and biothiols using naphthalimide-rhodamine dyads. Rhodamines 75-84 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 36-39 22705940-6 2012 The sliding velocity of rhodamine-phalloidin-bound actin filaments on HMM was measured using an in vitro motility assay. Rhodamines 24-33 actin Oryctolagus cuniculus 51-56 22900779-6 2012 The IC(50) values of (-)-THP and (+)-THP on rhodamine 123 (P-gp substrate) efflux were 48.6 and 20.0 microM, respectively, which showed obvious stereoselective difference. Rhodamines 44-53 ATP binding cassette subfamily B member 1 Homo sapiens 59-63 23183822-10 2012 Of note, miR-211- and pM-treated CSC demonstrated increased drug retention capacity, as observed by MDR1/P-gp mediated-Rhodamine 123 drug efflux activity assay. Rhodamines 119-128 microRNA 211 Homo sapiens 9-16 23183822-10 2012 Of note, miR-211- and pM-treated CSC demonstrated increased drug retention capacity, as observed by MDR1/P-gp mediated-Rhodamine 123 drug efflux activity assay. Rhodamines 119-128 ATP binding cassette subfamily B member 1 Homo sapiens 100-104 23183822-10 2012 Of note, miR-211- and pM-treated CSC demonstrated increased drug retention capacity, as observed by MDR1/P-gp mediated-Rhodamine 123 drug efflux activity assay. Rhodamines 119-128 phosphoglycolate phosphatase Homo sapiens 105-109 22858611-1 2012 Rhodamine S could emit strong and stable room temperature phosphorescence (RTP) on polyamide membrane (PAM) in the presence of heavy atom perturber Pb(2+). Rhodamines 0-11 MORN repeat containing 4 Homo sapiens 75-78 22858611-1 2012 Rhodamine S could emit strong and stable room temperature phosphorescence (RTP) on polyamide membrane (PAM) in the presence of heavy atom perturber Pb(2+). Rhodamines 0-11 peptidylglycine alpha-amidating monooxygenase Homo sapiens 103-106 23202936-9 2012 FACS analysis demonstrated a correlation of cell labeling between FITC-CaIX-P1 and rhodamine-labeled anti-CAIX-mAb in both HCT116 and HT29 cells. Rhodamines 83-92 carbonic anhydrase 9 Homo sapiens 106-110 22451472-3 2012 Multidrug resistance protein 1 blockade by the specific inhibitor reduced the percentage of rhodamine 123(low) cells in LDCs from aged mice (54.8% +- 2.6% to 13.2% +- 2.5%, p < .01). Rhodamines 92-101 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 0-30 22875192-1 2012 A new coumarin-rhodamine conjugate constitutes a unique example of the interrupted PET coupled TBET response for developing an imaging reagent for determining the intracellular distribution of Hg(2+) in MCF7 cells exposed to [Hg(2+)] as low as 2 ppb. Rhodamines 15-24 T-box transcription factor 21 Homo sapiens 95-99 22525746-6 2012 RESULTS: In rhodamine 123 efflux assay drugs inhibitory potency to P-gp could be ranked quetiapine>N-desmethylclozapine>clozapine>olanzapine. Rhodamines 12-21 phosphoglycolate phosphatase Mus musculus 67-71 22583690-2 2012 METHODS: To confirm that TNF-alpha induces epithelial barrier hyperpermeability by disrupting tight junction, Caco-2 cells were exposed to TNF-alpha, and changes in epithelial permeability (via TER assay), F-actin dynamics (via Rhodamine-phalloidin staining) and tight junction protein expression (via western blot) were monitored. Rhodamines 228-237 tumor necrosis factor Homo sapiens 25-34 22931670-3 2012 The results showed that after pretreated with S1P, the level of superoxide anion released by fMLP-activated neutrophils significantly increased; the Rhodamine 123 mean fluorescence intensity in S1P primed fMLP-activated neutrophils group was significantly higher than that in fMLP treatment group; PI3K and Akt proteins involved in the signal pathway of neutrophil respiratory burst. Rhodamines 149-158 formyl peptide receptor 1 Homo sapiens 93-97 22931670-3 2012 The results showed that after pretreated with S1P, the level of superoxide anion released by fMLP-activated neutrophils significantly increased; the Rhodamine 123 mean fluorescence intensity in S1P primed fMLP-activated neutrophils group was significantly higher than that in fMLP treatment group; PI3K and Akt proteins involved in the signal pathway of neutrophil respiratory burst. Rhodamines 149-158 formyl peptide receptor 1 Homo sapiens 205-209 22931670-3 2012 The results showed that after pretreated with S1P, the level of superoxide anion released by fMLP-activated neutrophils significantly increased; the Rhodamine 123 mean fluorescence intensity in S1P primed fMLP-activated neutrophils group was significantly higher than that in fMLP treatment group; PI3K and Akt proteins involved in the signal pathway of neutrophil respiratory burst. Rhodamines 149-158 formyl peptide receptor 1 Homo sapiens 205-209 22931670-3 2012 The results showed that after pretreated with S1P, the level of superoxide anion released by fMLP-activated neutrophils significantly increased; the Rhodamine 123 mean fluorescence intensity in S1P primed fMLP-activated neutrophils group was significantly higher than that in fMLP treatment group; PI3K and Akt proteins involved in the signal pathway of neutrophil respiratory burst. Rhodamines 149-158 AKT serine/threonine kinase 1 Homo sapiens 307-310 22506763-6 2012 This assay, which monitors the kinetics of the fluorescence polarization signal increase upon PRMT1 labeling by a rhodamine-containing cysteine-reactive probe, successfully identified two novel inhibitors selective for PRMT1 over other SAM-dependent methyltransferases. Rhodamines 114-123 protein arginine methyltransferase 1 Homo sapiens 94-99 22506763-6 2012 This assay, which monitors the kinetics of the fluorescence polarization signal increase upon PRMT1 labeling by a rhodamine-containing cysteine-reactive probe, successfully identified two novel inhibitors selective for PRMT1 over other SAM-dependent methyltransferases. Rhodamines 114-123 protein arginine methyltransferase 1 Homo sapiens 219-224 22386863-6 2012 The P-glycoprotein (P-gp) function assay in MES-Dx5 cells showed the potential of gelucire-based NPs in inhibiting rhodamine 123 efflux. Rhodamines 115-124 phosphoglycolate phosphatase Mus musculus 4-18 21882172-0 2012 Spectroscopic investigations to reveal the nature of interactions between the haem protein myoglobin and the dye rhodamine 6G. Rhodamines 113-122 myoglobin Homo sapiens 91-100 22386863-6 2012 The P-glycoprotein (P-gp) function assay in MES-Dx5 cells showed the potential of gelucire-based NPs in inhibiting rhodamine 123 efflux. Rhodamines 115-124 phosphoglycolate phosphatase Mus musculus 20-24 22550304-0 2012 Fluorescent labeling of calmodulin with bifunctional rhodamine. Rhodamines 53-62 calmodulin 2 Gallus gallus 24-34 22550304-3 2012 This protocol describes how to label chicken calmodulin (CaM) with bifunctional rhodamine (BR) at two engineered cysteine (Cys) residues (P66C and A73C) so that it cross-links the two Cys sites. Rhodamines 80-89 calmodulin 2 Gallus gallus 45-55 22550304-3 2012 This protocol describes how to label chicken calmodulin (CaM) with bifunctional rhodamine (BR) at two engineered cysteine (Cys) residues (P66C and A73C) so that it cross-links the two Cys sites. Rhodamines 80-89 calmodulin 2 Gallus gallus 57-60 22354094-3 2012 The nano-patterned SERS substrate, with excellent control and reproducibility of plasmon-polaritons generation, shows very efficient enhanced Raman signal in the presence of intrinsically fluorescent molecules such as cresyl violet, rhodamine, and green fluorescent protein. Rhodamines 233-242 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 19-23 22212563-5 2012 Apatinib treatment markedly increased the intracellular accumulation of doxorubicin and rhodamine 123 in K562/ADR cells and the accumulation of rhodamine 123 in the primary leukemia blasts with ABCB1 overexpression. Rhodamines 144-153 ATP binding cassette subfamily B member 1 Homo sapiens 194-199 22226881-6 2012 It also significantly increased intracellular accumulation (21-fold) of rhodamine 123 in HEK293 MDR1 cells. Rhodamines 72-81 ATP binding cassette subfamily B member 1 Homo sapiens 96-100 22420656-4 2012 METHODS: P-gp drug efflux activity was measured by an in-situ closed loop method with Rhodamine 123, a P-gp substrate. Rhodamines 86-95 ATP binding cassette subfamily B member 1 Homo sapiens 9-13 22420656-4 2012 METHODS: P-gp drug efflux activity was measured by an in-situ closed loop method with Rhodamine 123, a P-gp substrate. Rhodamines 86-95 ATP binding cassette subfamily B member 1 Homo sapiens 103-107 22420656-7 2012 KEY FINDINGS: ETP and morphine significantly decreased the intestinal Rhodamine 123 efflux activity of P-gp. Rhodamines 70-79 ATP binding cassette subfamily B member 1 Homo sapiens 103-107 21797847-3 2012 EXPERIMENTAL APPROACH: Intravital microscopy was used to determine whether ETR/B(2)R drives the accumulation of rhodamine-labelled leucocytes in the hamster cheek pouch (HCP). Rhodamines 112-121 bradykinin receptor B2 Homo sapiens 79-84 22201267-2 2012 By use of a photostable rhodamine attached specifically to Halo-tagged proteins in mitochondrial membranes, we were able to track and localize single protein complexes such as Tom20 and ATP synthase in suborganellar structures in live cells. Rhodamines 24-33 translocase of outer mitochondrial membrane 20 Homo sapiens 176-181 22300338-0 2012 New fluorogenic sensors for Hg2+ ions: through-bond energy transfer from pentaquinone to rhodamine. Rhodamines 89-98 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 28-31 22234375-5 2012 The architecture of the SERS-active substrate was varied using three adsorption strategies for incorporating a laser dye (rhodamine): alongside the nanoparticles into the polymer matrix, during the polymer cure and within nanoholes lithographed on the polymer. Rhodamines 122-131 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 24-28 22234375-6 2012 As a proof-of-concept, we obtained the SERS spectra of rhodamine for the three types of substrates. Rhodamines 55-64 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 39-43 22234375-8 2012 In the case of arrays of nanoholes, rhodamine molecules could be adsorbed directly on the gold surface, then yielding a well-resolved SERS spectrum for a small amount of analyte owing to the short-range interactions and the large longitudinal field component inside the nanoholes. Rhodamines 36-45 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 134-138 25786599-6 2012 In addition, we demonstrate that rhodamine-loaded MB can also be used for in vivo and ex vivo experimental setups, e.g., for analyzing MB binding to inflamed carotids using two-photon laser scanning microscopy, and for validating the binding of VEGFR2-targeted MB to tumor endothelium. Rhodamines 33-42 kinase insert domain receptor Homo sapiens 245-251 22176300-5 2012 Significantly, the new CS1-6 NIR dyes are superior to the traditional rhodamine dyes with both absorption and emission in the NIR region while retaining the rhodamine-like fluorescence ON-OFF switching mechanism. Rhodamines 70-79 chorionic somatomammotropin hormone 1 Homo sapiens 23-28 22291144-2 2012 To better understand how myoV navigates along actin, we used polarized total internal reflection fluorescence microscopy to examine angular changes of bifunctional rhodamine probes on the lever arms of single myoV molecules in vitro. Rhodamines 164-173 myosin VA Homo sapiens 209-213 22148475-5 2012 Incubation of MCF-7/Vin cells with 1 caused an increase in uptake and notably lowered the efflux rate of rhodamine 123. Rhodamines 105-114 long intergenic non-protein coding RNA 1191 Homo sapiens 20-23 22176300-5 2012 Significantly, the new CS1-6 NIR dyes are superior to the traditional rhodamine dyes with both absorption and emission in the NIR region while retaining the rhodamine-like fluorescence ON-OFF switching mechanism. Rhodamines 157-166 chorionic somatomammotropin hormone 1 Homo sapiens 23-28 22403486-14 2012 Further, biodistribution studies of rhodamine-loaded nanoparticles demonstrated that modification with the SynB peptide could not only improve the ability of PEG-GS nanoparticles to evade capture in the reticuloendothelial system but also enhance their efficiency in crossing the blood-brain barrier. Rhodamines 36-45 syncytin b Mus musculus 107-111 22470447-3 2012 Rhodamine 123, a member of the rhodamine family of flurone dyes, has been used to examine membrane transport by the ABCB1 gene product, MDR1. Rhodamines 31-40 ATP binding cassette subfamily B member 1 Homo sapiens 116-121 22416063-10 2012 Rhodamine efflux from CD56+ PBMCs was a statistically significant 51%-100% lower (p < .0001) with CBT-1 . Rhodamines 0-9 succinate dehydrogenase complex subunit D Homo sapiens 101-106 22470447-3 2012 Rhodamine 123, a member of the rhodamine family of flurone dyes, has been used to examine membrane transport by the ABCB1 gene product, MDR1. Rhodamines 31-40 ATP binding cassette subfamily B member 1 Homo sapiens 136-140 22018584-0 2012 Reversible "off-on" fluorescent chemosensor for Hg2+ based on rhodamine derivative. Rhodamines 62-71 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 48-51 21920352-1 2011 P-Glycoprotein (Pgp) inhibition by three sets of four isomers of N,N-bis(cyclohexanol)amine aryl esters was assessed on rhodamine 123 (R123) efflux in human MDR1-gene transfected mouse T-lymphoma L5178 cells and on Sf9 ATPase activity. Rhodamines 120-129 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 21920352-1 2011 P-Glycoprotein (Pgp) inhibition by three sets of four isomers of N,N-bis(cyclohexanol)amine aryl esters was assessed on rhodamine 123 (R123) efflux in human MDR1-gene transfected mouse T-lymphoma L5178 cells and on Sf9 ATPase activity. Rhodamines 120-129 ATP binding cassette subfamily B member 1 Homo sapiens 16-19 22027958-0 2011 Facile synthesis of rhodamine-based highly sensitive and fast responsive colorimetric and off-on fluorescent reversible chemosensors for Hg2+: preparation of a fluorescent thin film sensor. Rhodamines 20-29 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 137-140 21685928-4 2011 P-GP function was investigated via measuring tissue-to-plasma concentration ratios and body fluid excretion percentages of rhodamine 123. Rhodamines 123-132 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 0-4 20676745-6 2011 The results demonstrated that increased intracellular accumulation of rhodamine 123 and increased fluorescence of calcein were observed after YC-1 treatment. Rhodamines 70-79 RNA binding motif single stranded interacting protein 1 Homo sapiens 142-146 21851848-8 2011 Accumulation studies demonstrated 31-38% decrease in rhodamine 123 intracellular levels when LS-180 cells were treated with the investigated compounds as a result of P-gp induction. Rhodamines 53-62 ATP binding cassette subfamily B member 1 Homo sapiens 166-170 21731939-0 2011 A new rhodamine based colorimetric "off-on" fluorescence sensor selective for Pd2+ along with the first bound X-ray crystal structure. Rhodamines 6-15 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 78-81 21763326-7 2011 KEY FINDINGS: MDR1 blockade by the specific inhibitor verapamil reduced the percentage of rhodamine 123(low) cells in LDCs (from 31.8+-6.3% to 11.8+-2.8%, p<0.02). Rhodamines 90-99 ATP binding cassette subfamily B member 1 Homo sapiens 14-18 20196146-5 2011 Rhodamine assay also revealed that hydrocinchonine, cinchonine, and quinidine effectively enhanced the accumulation of a P-gp substrate, rhodamine in TAX-treated MES-SA/DX5 cells compared with TAX-treated control. Rhodamines 0-9 phosphoglycolate phosphatase Homo sapiens 121-125 20196146-5 2011 Rhodamine assay also revealed that hydrocinchonine, cinchonine, and quinidine effectively enhanced the accumulation of a P-gp substrate, rhodamine in TAX-treated MES-SA/DX5 cells compared with TAX-treated control. Rhodamines 137-146 phosphoglycolate phosphatase Homo sapiens 121-125 21502729-3 2011 The presence of ORF2-EGFP fusion protein was demonstrated by dual signals of green fluorescence and anti-PCV2 antibodies conjugated with rhodamine in an immunofluorescence assay (IFA). Rhodamines 137-146 capsid protein Porcine circovirus 2 16-20 21711510-10 2011 Moreover, the markedly increased Abcb1a/Abcb1b expression was correlated to an efficient Rhodamine 123 efflux, which was completely inhibited by verapamil, a well-known Abcb1a/Abcb1b inhibitor. Rhodamines 89-98 ATP-binding cassette, sub-family B (MDR/TAP), member 1A Mus musculus 33-39 21786801-6 2011 All the coumarin-, cresyl violet- and rhodamine-based fluorogenic probes turned out to be good substrates for most GSTs, especially for GSTA(1-1), in terms of strong fluorescence increases (71-1200-fold), high k(cat)/K(m) values (10(4)-10(7) M(-1) s(-1)) and significant rate enhancements (10(6)-10(9)-fold). Rhodamines 38-47 hematopoietic prostaglandin D synthase Homo sapiens 115-119 21786801-6 2011 All the coumarin-, cresyl violet- and rhodamine-based fluorogenic probes turned out to be good substrates for most GSTs, especially for GSTA(1-1), in terms of strong fluorescence increases (71-1200-fold), high k(cat)/K(m) values (10(4)-10(7) M(-1) s(-1)) and significant rate enhancements (10(6)-10(9)-fold). Rhodamines 38-47 glutathione S-transferase alpha 1 Homo sapiens 136-144 21372002-7 2011 The MPO-NAA-induced production of reactive oxygen species was assessed using oxidation of dihydrorhodamine (DHR) to rhodamine. Rhodamines 97-106 myeloperoxidase Homo sapiens 4-7 21711510-10 2011 Moreover, the markedly increased Abcb1a/Abcb1b expression was correlated to an efficient Rhodamine 123 efflux, which was completely inhibited by verapamil, a well-known Abcb1a/Abcb1b inhibitor. Rhodamines 89-98 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 40-46 21711510-10 2011 Moreover, the markedly increased Abcb1a/Abcb1b expression was correlated to an efficient Rhodamine 123 efflux, which was completely inhibited by verapamil, a well-known Abcb1a/Abcb1b inhibitor. Rhodamines 89-98 ATP-binding cassette, sub-family B (MDR/TAP), member 1A Mus musculus 169-175 21711510-10 2011 Moreover, the markedly increased Abcb1a/Abcb1b expression was correlated to an efficient Rhodamine 123 efflux, which was completely inhibited by verapamil, a well-known Abcb1a/Abcb1b inhibitor. Rhodamines 89-98 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 176-182 21421215-5 2011 The sensitivity and reproducibility of the substrate were confirmed using a common SERS probe molecule, rhodamine 6G. Rhodamines 104-113 seryl-tRNA synthetase 1 Homo sapiens 83-87 21262289-6 2011 Rhodamine labeled EGa1-micelles showed substantially higher binding as well as uptake by EGFR over-expressing cancer cells (A431 and UM-SCC-14C) than untargeted rhodamine labeled micelles. Rhodamines 0-9 epidermal growth factor receptor Mus musculus 89-93 21289467-6 2011 The elevation of the oocyte Pgp level was associated with increased activity of rhodamine 6G efflux from the oocyte, and its efflux was suppressed by verapamil, an inhibitor of Pgp. Rhodamines 80-89 ATP binding cassette subfamily B member 1 Homo sapiens 28-31 21729546-7 2011 The acidification resulted in the increased rhodamine 123 accumulation in HL-60, MSC and CD34(+) cells without P-gp activity. Rhodamines 44-53 CD34 molecule Homo sapiens 89-93 21452853-9 2011 Consistent with these results, FSBA blocked efflux of rhodamine 123 from P-gp-expressing cells. Rhodamines 54-63 ATP binding cassette subfamily B member 1 Homo sapiens 73-77 21684029-6 2011 Rhodamine labeled EGa1-micelles showed substantially higher binding as well as uptake by EGFR over-expressing cancer cells (A431 and UM-SCC-14C) than untargeted rhodamine labeled micelles. Rhodamines 0-9 epidermal growth factor receptor Mus musculus 89-93 21385940-5 2011 Qualitative analysis using rhodamine-conjugated phalloidin immunofluorescence indicated that leptin stimulated actin cytoskeletal reorganization and enhanced stress fiber formation. Rhodamines 27-36 leptin Rattus norvegicus 93-99 21780390-1 2011 Luminescent nanorods of potassium acid phthalate (KAP) doped with rhodamine 6G (Rh 6G) dye molecules were grown by template assisted crystallization. Rhodamines 66-75 napsin A aspartic peptidase Homo sapiens 50-53 20857089-4 2011 Cytotoxicity of doxorubicin (0-100 muM) and paraquat (0-1,000 muM) was evaluated for a maximum period of 96 h. In doxorubicin-exposed cells, P-gp expression and transport activity were evaluated by flow cytometry, using a fluorescein isothiocyanate-conjugated antibody and the P-gp fluorescent subtract rhodamine 123, respectively. Rhodamines 303-312 ATP binding cassette subfamily B member 1 Homo sapiens 141-145 21286625-0 2011 A highly specific rhodamine-based colorimetric probe for hypochlorites: a new sensing strategy and real application in tap water. Rhodamines 18-27 nuclear RNA export factor 1 Homo sapiens 119-122 21097518-11 2011 Microscopic studies revealed that the vascular constrained, rhodamine-labeled alpha(v)beta(3)-GNBs homed specifically to immature neovasculature (PECAM(+), Tie-2(-)) along the immediate tumor periphery, but not to nearby mature microvasculature (PECAM(+), Tie-2(+)). Rhodamines 60-69 platelet/endothelial cell adhesion molecule 1 Mus musculus 146-151 21097518-11 2011 Microscopic studies revealed that the vascular constrained, rhodamine-labeled alpha(v)beta(3)-GNBs homed specifically to immature neovasculature (PECAM(+), Tie-2(-)) along the immediate tumor periphery, but not to nearby mature microvasculature (PECAM(+), Tie-2(+)). Rhodamines 60-69 TEK receptor tyrosine kinase Mus musculus 156-161 21097518-11 2011 Microscopic studies revealed that the vascular constrained, rhodamine-labeled alpha(v)beta(3)-GNBs homed specifically to immature neovasculature (PECAM(+), Tie-2(-)) along the immediate tumor periphery, but not to nearby mature microvasculature (PECAM(+), Tie-2(+)). Rhodamines 60-69 platelet/endothelial cell adhesion molecule 1 Mus musculus 246-251 21097518-11 2011 Microscopic studies revealed that the vascular constrained, rhodamine-labeled alpha(v)beta(3)-GNBs homed specifically to immature neovasculature (PECAM(+), Tie-2(-)) along the immediate tumor periphery, but not to nearby mature microvasculature (PECAM(+), Tie-2(+)). Rhodamines 60-69 TEK receptor tyrosine kinase Mus musculus 256-261 20955791-8 2011 Changes in expression were confined mostly to MDR1 and CYP3A4: in LS180 cells, treatment for 3 days increased MDR1 and CYP3A4 but not MRP2 mRNA, and elevated P-gp and CYP3A4 protein expression that led to decreased cellular accumulation of [(3)H]digoxin and rhodamine 123, and enhanced testosterone 6beta-hydroxylase activity towards T2007, respectively. Rhodamines 258-267 ATP binding cassette subfamily B member 1 Homo sapiens 46-50 21081657-8 2011 Tariquidar inhibited Pgp-mediated rhodamine efflux from CD56(+) cells and reduced (99m)Tc-sestamibi clearance from the liver. Rhodamines 34-43 ATP binding cassette subfamily B member 1 Homo sapiens 21-24 21145107-7 2011 Drug transport in BCEC-1 was investigated by FACS analysis using the fluorescent P-gp substrate Rhodamine 123. Rhodamines 96-105 phosphoglycolate phosphatase Bos taurus 81-85 21145107-8 2011 Inhibition of Rhodamine 123 efflux by the P-gp inhibitors Verapamil and PSC833 confirmed functional expression of P-gp in BCEC-1. Rhodamines 14-23 phosphoglycolate phosphatase Bos taurus 42-46 21145107-8 2011 Inhibition of Rhodamine 123 efflux by the P-gp inhibitors Verapamil and PSC833 confirmed functional expression of P-gp in BCEC-1. Rhodamines 14-23 phosphoglycolate phosphatase Bos taurus 114-118 20955791-3 2011 P-gp and CYP3A4 activities were assayed by [(3)H]digoxin and rhodamine 123 cellular retention and testosterone 6beta-hydroxylation, respectively. Rhodamines 61-70 phosphoglycolate phosphatase Homo sapiens 0-4 20955791-8 2011 Changes in expression were confined mostly to MDR1 and CYP3A4: in LS180 cells, treatment for 3 days increased MDR1 and CYP3A4 but not MRP2 mRNA, and elevated P-gp and CYP3A4 protein expression that led to decreased cellular accumulation of [(3)H]digoxin and rhodamine 123, and enhanced testosterone 6beta-hydroxylase activity towards T2007, respectively. Rhodamines 258-267 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 55-61 21057677-2 2010 The emission behavior of ABPX series is directly opposite to the concentration quenching of conventional rhodamine dyes. Rhodamines 105-114 filamin A Homo sapiens 25-29 20955791-3 2011 P-gp and CYP3A4 activities were assayed by [(3)H]digoxin and rhodamine 123 cellular retention and testosterone 6beta-hydroxylation, respectively. Rhodamines 61-70 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 9-15 20955690-6 2011 MDR1 activity was increased by 50% in APAP treated rats, as evaluated by serosal to mucosal secretion of rhodamine 123 in everted intestinal sacs. Rhodamines 105-114 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 0-4 21147877-6 2011 We quantitatively assessed the filamentous to globular actin ratio and show that increased stress fiber formation, visualized by rhodamine-phalloidin immunofluorescence, in response to adiponectin, is achieved via stimulating Ras homolog gene family A (RhoA) activity, determined using G-LISA RhoA activation assay kit. Rhodamines 129-138 adiponectin, C1Q and collagen domain containing Rattus norvegicus 185-196 21147877-6 2011 We quantitatively assessed the filamentous to globular actin ratio and show that increased stress fiber formation, visualized by rhodamine-phalloidin immunofluorescence, in response to adiponectin, is achieved via stimulating Ras homolog gene family A (RhoA) activity, determined using G-LISA RhoA activation assay kit. Rhodamines 129-138 ras homolog family member A Rattus norvegicus 253-257 21147877-6 2011 We quantitatively assessed the filamentous to globular actin ratio and show that increased stress fiber formation, visualized by rhodamine-phalloidin immunofluorescence, in response to adiponectin, is achieved via stimulating Ras homolog gene family A (RhoA) activity, determined using G-LISA RhoA activation assay kit. Rhodamines 129-138 ras homolog family member A Rattus norvegicus 293-297 22358098-7 2011 Moreover, DIOXOL (at 10 muM) significantly inhibited P-gp transport function by more than twofold comparing to control, untreated cells that was demonstrated using rhodamine 123-based functional test. Rhodamines 164-173 phosphoglycolate phosphatase Homo sapiens 53-57 19788373-1 2010 Primitive marrow lineage-negative rhodamine low and Hoechst low (LRH) stem cells isolated on the basis of quiescence respond to the cytokines thrombopoietin, FLT3L, and steel factor by synchronously progressing through cell cycle. Rhodamines 34-43 thrombopoietin Mus musculus 142-156 20844484-3 2010 In patients with hypothyroidism, normalization of thyroid function was associated with a 1.8-fold increase in mRNA expression and a 26% increase in rhodamine efflux from CD56(+) cells. Rhodamines 148-157 neural cell adhesion molecule 1 Homo sapiens 170-174 20846144-5 2010 The energy-dependent efflux of rhodamine 6G was increased by VMR1 deletion. Rhodamines 31-40 putative ATP-binding cassette multidrug transporter VMR1 Saccharomyces cerevisiae S288C 61-65 20608983-3 2010 Here, we report that loss of the type 2A-related serine/threonine protein phosphatase Sit4p renders yeast cells sensitive to cycloheximide, azoles, daunorubicin and rhodamine 6G. Rhodamines 165-174 type 2A-related serine/threonine-protein phosphatase SIT4 Saccharomyces cerevisiae S288C 86-91 20499920-4 2010 These gold nanoparticle structures were shown to yield a large SERS enhancement for Rhodamine 6G. Rhodamines 84-93 seryl-tRNA synthetase 1 Homo sapiens 63-67 20132313-6 2010 These compounds almost completely inhibited the efflux of the Pdr5p fluorescent substrate Rhodamine 6G and at 25 muM chemosensitized the Pdr5p-overexpressing strain AD124567 to fluconazole (0.4 mg mL(-1)). Rhodamines 90-99 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 62-67 20132313-6 2010 These compounds almost completely inhibited the efflux of the Pdr5p fluorescent substrate Rhodamine 6G and at 25 muM chemosensitized the Pdr5p-overexpressing strain AD124567 to fluconazole (0.4 mg mL(-1)). Rhodamines 90-99 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 137-142 20417333-1 2010 We introduce a new rhodamine-based fluorescent chemosensor, FD8 which exhibits a distinct two-photon excited fluorescence (TPEF) on/off characteristic upon binding Cr(3+) ions. Rhodamines 19-28 transmembrane protein with EGF like and two follistatin like domains 2 Homo sapiens 123-127 20188976-1 2010 A new Rhodamine-based chemosensor RBSN designed for the selective detection of Hg(2+) in aqueous media is synthesized and structural characterized. Rhodamines 6-15 rabenosyn, RAB effector Homo sapiens 34-38 20230790-4 2010 In vitro, the P-gp antagonist PSC833, a non-calcineurin-inhibitory cyclosporine A analogue, specifically inhibited cellular efflux of the P-gp substrate rhodamine-123 in wild-type CD3(+) T cells and MHC class II(+) APCs but not their P-gp knockout counterparts that lacked rhodamine-123 efflux capacity. Rhodamines 153-162 phosphoglycolate phosphatase Mus musculus 14-18 20230790-4 2010 In vitro, the P-gp antagonist PSC833, a non-calcineurin-inhibitory cyclosporine A analogue, specifically inhibited cellular efflux of the P-gp substrate rhodamine-123 in wild-type CD3(+) T cells and MHC class II(+) APCs but not their P-gp knockout counterparts that lacked rhodamine-123 efflux capacity. Rhodamines 153-162 phosphoglycolate phosphatase Mus musculus 138-142 20230790-4 2010 In vitro, the P-gp antagonist PSC833, a non-calcineurin-inhibitory cyclosporine A analogue, specifically inhibited cellular efflux of the P-gp substrate rhodamine-123 in wild-type CD3(+) T cells and MHC class II(+) APCs but not their P-gp knockout counterparts that lacked rhodamine-123 efflux capacity. Rhodamines 153-162 CD3 antigen, epsilon polypeptide Mus musculus 180-183 20230790-4 2010 In vitro, the P-gp antagonist PSC833, a non-calcineurin-inhibitory cyclosporine A analogue, specifically inhibited cellular efflux of the P-gp substrate rhodamine-123 in wild-type CD3(+) T cells and MHC class II(+) APCs but not their P-gp knockout counterparts that lacked rhodamine-123 efflux capacity. Rhodamines 153-162 phosphoglycolate phosphatase Mus musculus 138-142 20623626-8 2010 MCF-7-Chk cells effluxed twice as much rhodamine-123 compared to MCF-7 cells. Rhodamines 39-48 choline kinase alpha Homo sapiens 6-9 19898868-6 2010 Doxorubicin also induced up-regulation of P-gp functional activities, as intracellular retention of rhodamine was decreased; however, 2.0 microg/ml tetrandrine significantly inhibited the overexpression of doxorubicin-induced mdr1 mRNA/P-gp. Rhodamines 100-109 phosphoglycolate phosphatase Homo sapiens 42-46 20146400-5 2010 The introduction of the D853Y mutation into gain-of-function Pdr3p suppressed the transcription of the PDR3 and PDR5 genes and reduced both the rhodamine 6G efflux rate and the drug resistance level in corresponding double mutants. Rhodamines 144-153 drug-responsive transcription factor PDR3 Saccharomyces cerevisiae S288C 61-66 20146400-5 2010 The introduction of the D853Y mutation into gain-of-function Pdr3p suppressed the transcription of the PDR3 and PDR5 genes and reduced both the rhodamine 6G efflux rate and the drug resistance level in corresponding double mutants. Rhodamines 144-153 drug-responsive transcription factor PDR3 Saccharomyces cerevisiae S288C 103-107 20146400-5 2010 The introduction of the D853Y mutation into gain-of-function Pdr3p suppressed the transcription of the PDR3 and PDR5 genes and reduced both the rhodamine 6G efflux rate and the drug resistance level in corresponding double mutants. Rhodamines 144-153 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 112-116 19788373-1 2010 Primitive marrow lineage-negative rhodamine low and Hoechst low (LRH) stem cells isolated on the basis of quiescence respond to the cytokines thrombopoietin, FLT3L, and steel factor by synchronously progressing through cell cycle. Rhodamines 34-43 FMS-like tyrosine kinase 3 ligand Mus musculus 158-163 19954837-5 2010 To further understand the bi-functionality, we labeled the SPT7pTL and PGA-alpha-MSH with YOYO-1 and Rhodamine, respectively, to follow its intracellular pathway by confocal microscopy. Rhodamines 101-110 proopiomelanocortin Homo sapiens 75-84 20298597-6 2010 GIVaPLA2 enzyme activity was analyzed using [14C-PAPC] as specific substrate F-actin polymerization and cell structure were examined after rhodamine-phalloidin staining. Rhodamines 139-148 coiled-coil domain containing 88A Homo sapiens 0-8 20121943-9 2010 Thus, P-glycoprotein appears to pump rhodamines from the cytoplasmic leaflet either to the outer leaflet or to the outer medium. Rhodamines 37-47 ATP binding cassette subfamily B member 1 Homo sapiens 6-20 19761200-2 2009 In response to binding cationic lipophilic compounds, including ethidium and rhodamine 6G, QacR dissociates from the qacA operator alleviating repression. Rhodamines 77-86 QacA Staphylococcus aureus 117-121 19933268-0 2010 Impact of disease-causing SUR1 mutations on the KATP channel subunit interface probed with a rhodamine protection assay. Rhodamines 93-102 ATP binding cassette subfamily C member 8 Homo sapiens 26-30 19933268-2 2010 The conformation of the interface between these two subunits can be monitored using a rhodamine 123 (Rho) protection assay because Rho blocks Kir6.2 with an efficiency that depends on the relative position of transmembrane domain (TMD) 0 of the associated SUR (Hosy, E., Derand, R., Revilloud, J., and Vivaudou, M. (2007) J. Physiol. Rhodamines 86-95 potassium inwardly rectifying channel subfamily J member 11 Homo sapiens 142-148 19933268-2 2010 The conformation of the interface between these two subunits can be monitored using a rhodamine 123 (Rho) protection assay because Rho blocks Kir6.2 with an efficiency that depends on the relative position of transmembrane domain (TMD) 0 of the associated SUR (Hosy, E., Derand, R., Revilloud, J., and Vivaudou, M. (2007) J. Physiol. Rhodamines 86-95 ATP binding cassette subfamily C member 8 Homo sapiens 256-259 19783150-3 2010 In addition to being lipophilic cations, like (99m)Tc-MIBI, rhodamine dyes are known to accumulate in the myocardium and are substrates for Pgp, the protein implicated in MDR1 multidrug resistance. Rhodamines 60-69 phosphoglycolate phosphatase Homo sapiens 140-143 19783150-3 2010 In addition to being lipophilic cations, like (99m)Tc-MIBI, rhodamine dyes are known to accumulate in the myocardium and are substrates for Pgp, the protein implicated in MDR1 multidrug resistance. Rhodamines 60-69 ATP binding cassette subfamily B member 1 Homo sapiens 171-175 19684997-2 2009 Exposure to a known mammalian inhibitor (verapamil, 10 1M) and inducer (rhodamine 123, 3 1M) on the transport protein P-glycoprotein (Pgp) was investigated in the liver of the western mosquitofish and bluegill sunfish. Rhodamines 72-81 ATP binding cassette subfamily B member 1 Homo sapiens 118-132 19684997-2 2009 Exposure to a known mammalian inhibitor (verapamil, 10 1M) and inducer (rhodamine 123, 3 1M) on the transport protein P-glycoprotein (Pgp) was investigated in the liver of the western mosquitofish and bluegill sunfish. Rhodamines 72-81 ATP binding cassette subfamily B member 1 Homo sapiens 134-137 19761200-2 2009 In response to binding cationic lipophilic compounds, including ethidium and rhodamine 6G, QacR dissociates from the qacA operator alleviating repression. Rhodamines 77-86 QacR Staphylococcus aureus 91-95 19481575-1 2009 We evaluated the benefits of a novel formulation of vasoactive intestinal peptide (VIP) based on the incorporation of VIP-loaded rhodamine-conjugated liposomes (VIP-Rh-Lip) within hyaluronic acid (HA) gel (Gel-VIP-Rh-Lip) for the treatment of endotoxin-induced uveitis (EIU) in comparison with VIP-Rh-Lip alone. Rhodamines 129-138 vasoactive intestinal peptide Rattus norvegicus 83-86 19481575-1 2009 We evaluated the benefits of a novel formulation of vasoactive intestinal peptide (VIP) based on the incorporation of VIP-loaded rhodamine-conjugated liposomes (VIP-Rh-Lip) within hyaluronic acid (HA) gel (Gel-VIP-Rh-Lip) for the treatment of endotoxin-induced uveitis (EIU) in comparison with VIP-Rh-Lip alone. Rhodamines 129-138 vasoactive intestinal peptide Rattus norvegicus 118-121 19481575-1 2009 We evaluated the benefits of a novel formulation of vasoactive intestinal peptide (VIP) based on the incorporation of VIP-loaded rhodamine-conjugated liposomes (VIP-Rh-Lip) within hyaluronic acid (HA) gel (Gel-VIP-Rh-Lip) for the treatment of endotoxin-induced uveitis (EIU) in comparison with VIP-Rh-Lip alone. Rhodamines 129-138 vasoactive intestinal peptide Rattus norvegicus 118-121 19481575-1 2009 We evaluated the benefits of a novel formulation of vasoactive intestinal peptide (VIP) based on the incorporation of VIP-loaded rhodamine-conjugated liposomes (VIP-Rh-Lip) within hyaluronic acid (HA) gel (Gel-VIP-Rh-Lip) for the treatment of endotoxin-induced uveitis (EIU) in comparison with VIP-Rh-Lip alone. Rhodamines 129-138 vasoactive intestinal peptide Rattus norvegicus 118-121 19481575-1 2009 We evaluated the benefits of a novel formulation of vasoactive intestinal peptide (VIP) based on the incorporation of VIP-loaded rhodamine-conjugated liposomes (VIP-Rh-Lip) within hyaluronic acid (HA) gel (Gel-VIP-Rh-Lip) for the treatment of endotoxin-induced uveitis (EIU) in comparison with VIP-Rh-Lip alone. Rhodamines 129-138 vasoactive intestinal peptide Rattus norvegicus 118-121 19814863-6 2009 Verapamil, a competitive inhibitor of P-gp, significantly inhibited ileal clearance of rhodamine 123 to the lumen at 24 h after reperfusion, suggesting that P-gp was working at this time. Rhodamines 87-96 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 38-42 19814863-6 2009 Verapamil, a competitive inhibitor of P-gp, significantly inhibited ileal clearance of rhodamine 123 to the lumen at 24 h after reperfusion, suggesting that P-gp was working at this time. Rhodamines 87-96 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 157-161 19760117-5 2010 Laser scanning microscopy of fungal cells exposed to rhodamine-labeled Pr-1 revealed that the protein accumulated and was localized on the cell surface. Rhodamines 53-62 transmembrane protein 37 Homo sapiens 71-75 19834649-7 2010 These experiments demonstrated that: i) both constructs expressed in the generated transfected cell line are functional; ii) the estimated pEYFP-actin: endogenous beta-actin ratio is within the limits required for the functional integrity of the actin filaments; and iii) pEYFP-actin and rhodamine-phalloidine-stained F-actin structures colocalize and display comparable reorganization patterns in pharmacologically challenged cells. Rhodamines 288-297 POTE ankyrin domain family member F Homo sapiens 163-173 20460821-2 2010 KP018 from Ellipeiopsis cherrevensis and AT80 from Ancistrocladus tectorius increased both rhodamine 123, a typical P-gp substrate, and [(3)H]paclitaxel uptake in PR-HepG2 cells. Rhodamines 91-100 ATP binding cassette subfamily B member 1 Homo sapiens 116-120 19726755-5 2010 Membrane vesicles from stably transfected CHO cells expressing recombinant SMDR2 show significant increases in rhodamine transport and ATP hydrolysis compared with those from control cells or cells transfected with empty vector. Rhodamines 111-120 smdr2 Schistosoma mansoni 75-80 19907082-4 2009 In the first section, rhodamine-derived Hg2+ ion sensors have been reviewed according to the essential mechanisms that work together with the spirolactam ring opening reaction. Rhodamines 22-31 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 40-43 19761200-6 2009 Furthermore, although mutation of the majority of residues contacting rhodamine 6G exerted moderate effects on QacR-rhodamine 6G binding, mutation of Leu(54) and Gln(96), and cumulative mutations involving these with Tyr(93) and Tyr(123), imparted a dramatic decrease in QacR-rhodamine 6G binding affinity. Rhodamines 70-79 QacR Staphylococcus aureus 111-115 19761200-6 2009 Furthermore, although mutation of the majority of residues contacting rhodamine 6G exerted moderate effects on QacR-rhodamine 6G binding, mutation of Leu(54) and Gln(96), and cumulative mutations involving these with Tyr(93) and Tyr(123), imparted a dramatic decrease in QacR-rhodamine 6G binding affinity. Rhodamines 70-79 QacR Staphylococcus aureus 271-275 19761200-6 2009 Furthermore, although mutation of the majority of residues contacting rhodamine 6G exerted moderate effects on QacR-rhodamine 6G binding, mutation of Leu(54) and Gln(96), and cumulative mutations involving these with Tyr(93) and Tyr(123), imparted a dramatic decrease in QacR-rhodamine 6G binding affinity. Rhodamines 116-125 QacR Staphylococcus aureus 111-115 19761200-6 2009 Furthermore, although mutation of the majority of residues contacting rhodamine 6G exerted moderate effects on QacR-rhodamine 6G binding, mutation of Leu(54) and Gln(96), and cumulative mutations involving these with Tyr(93) and Tyr(123), imparted a dramatic decrease in QacR-rhodamine 6G binding affinity. Rhodamines 116-125 QacR Staphylococcus aureus 111-115 19761200-8 2009 Additionally, despite maintaining a high affinity for ethidium, QacR mutants involving Leu(54), Tyr(93), Gln(96), and Tyr(123), which denote the interface between the rhodamine 6G and ethidium subpockets, were unable to be induced from operator DNA in the presence of ethidium in S. aureus. Rhodamines 167-176 QacR Staphylococcus aureus 64-68 19947169-6 2009 The effects of guggulsterone on P-glycoprotein activity were evaluated by measuring rhodamine 123 (Rh123)-associated mean fluorescence intensity and P-glycoprotein expression on the basis of the flow cytometric technology, respectively. Rhodamines 84-93 ATP binding cassette subfamily B member 1 Homo sapiens 32-46 19576864-6 2009 Additional evidence was obtained from time-resolved in situ fluorescence spectroscopic monitoring of the Pgp efflux dynamics in transfected Caco-2 cells which yielded significantly reduced transporter efficiencies for the Pgp substrate Rhodamine 123. Rhodamines 236-245 ATP binding cassette subfamily B member 1 Homo sapiens 105-108 19576864-6 2009 Additional evidence was obtained from time-resolved in situ fluorescence spectroscopic monitoring of the Pgp efflux dynamics in transfected Caco-2 cells which yielded significantly reduced transporter efficiencies for the Pgp substrate Rhodamine 123. Rhodamines 236-245 ATP binding cassette subfamily B member 1 Homo sapiens 222-225 19538007-7 2009 Surface charge of liposomes did not affect the rhodamine retention, whereas the incorporation of cholesterol and polyethyleneglycol-attached lipids was effective in further increasing the rhodamine retention in MCF-7/Pgp cells. Rhodamines 188-197 ATP binding cassette subfamily B member 1 Homo sapiens 217-220 19596835-8 2009 We also find that a rhodamine dye conjugated to a 5beta-reduced 3alpha-hydroxy steroid is a particularly potent and effective photopotentiator, with minimal baseline receptor activity up to 10 muM. Rhodamines 20-29 latexin Homo sapiens 193-196 19297331-10 2009 As expected, surface binding of rhodamine-labeled EGF increased with green fluorescent protein-EGFR expression level. Rhodamines 32-41 epidermal growth factor receptor Homo sapiens 95-99 19616959-1 2009 Two kinds of rhodamine modified beta-cyclodextrins (R-1 and R-2), which are coupled up ethylene diamine (EDA) and tetraethylene pentamine (TEPA) between Rh B and beta-cyclodextrin, respectively, have been synthesized. Rhodamines 13-22 CD1b molecule Homo sapiens 32-63 19465096-4 2009 P-glycoprotein (P-gp) does not affect melatonin absorption but transported rhodamine 123, a well-known P-gp substrate. Rhodamines 75-84 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 0-14 19465096-4 2009 P-glycoprotein (P-gp) does not affect melatonin absorption but transported rhodamine 123, a well-known P-gp substrate. Rhodamines 75-84 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 16-20 19465096-4 2009 P-glycoprotein (P-gp) does not affect melatonin absorption but transported rhodamine 123, a well-known P-gp substrate. Rhodamines 75-84 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 103-107 19480464-5 2009 Rhodamine derivatives were conjugated to avidin and trastuzumab, which target D-galactose receptor and HER2/neu antigen, respectively. Rhodamines 0-9 erb-b2 receptor tyrosine kinase 2 Mus musculus 103-111 19538007-0 2009 Liposome composition is important for retention of liposomal rhodamine in P-glycoprotein-overexpressing cancer cells. Rhodamines 61-70 ATP binding cassette subfamily B member 1 Homo sapiens 74-88 19538007-5 2009 Pgp-expression decreased the rhodamine retention in MCF-7 cells, suggesting that Pgp is functional. Rhodamines 29-38 ATP binding cassette subfamily B member 1 Homo sapiens 0-3 19538007-5 2009 Pgp-expression decreased the rhodamine retention in MCF-7 cells, suggesting that Pgp is functional. Rhodamines 29-38 ATP binding cassette subfamily B member 1 Homo sapiens 81-84 19538007-6 2009 Liposome loading increased rhodamine retention in MCF-7/Pgp cells, but not in MCF-7/WT cells. Rhodamines 27-36 ATP binding cassette subfamily B member 1 Homo sapiens 56-59 19564743-3 2009 P-gp function was measured using the verapamil-sensitive Rhodamine efflux. Rhodamines 57-66 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 19549365-7 2009 The function of P-gp in K562/A02 cells weakened along with decrease of intracellular acidification, the intracellular acidification significantly increased the accumulation of Rhodamine 123 (Rh 123) and suppressed the efflux of Rh 123 mediated by P-gp. Rhodamines 176-185 phosphoglycolate phosphatase Homo sapiens 16-20 19402665-0 2009 Rhodamine inhibitors of P-glycoprotein: an amide/thioamide "switch" for ATPase activity. Rhodamines 0-9 ATP binding cassette subfamily B member 1 Homo sapiens 24-38 19402665-0 2009 Rhodamine inhibitors of P-glycoprotein: an amide/thioamide "switch" for ATPase activity. Rhodamines 0-9 dynein axonemal heavy chain 8 Homo sapiens 72-78 19474307-5 2009 The rhodamine-, OR Green-, or Cy3-labeled ligands had high binding affinity for DAT and enabled specific labeling of DAT in live neurons and visualization by confocal imaging. Rhodamines 4-13 solute carrier family 6 member 3 Homo sapiens 80-83 19474307-5 2009 The rhodamine-, OR Green-, or Cy3-labeled ligands had high binding affinity for DAT and enabled specific labeling of DAT in live neurons and visualization by confocal imaging. Rhodamines 4-13 solute carrier family 6 member 3 Homo sapiens 117-120 19232637-11 2009 A Raman probe, Rhodamine 6G (Rh 6G), has been found to be suited for the surface modification of the gold particles and it has also been demonstrated that the larger particles show better SERS signal than the corresponding smaller ones. Rhodamines 15-24 seryl-tRNA synthetase 1 Homo sapiens 188-192 19429419-3 2009 The change in the mRNA expression of MDR1 was accompanied by a change in the CsA-dependent intracellular accumulation of rhodamine 123. Rhodamines 121-130 ATP binding cassette subfamily B member 1 Homo sapiens 37-41 19188399-9 2009 They also correlated with the 50% inhibitory concentration for inhibition of Pdr5p-mediated transport of rhodamine 6G in isolated plasma membranes. Rhodamines 105-114 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 77-82 19174508-7 2009 Compared with WT, stimulation-induced increases in rhodamine-123 fluorescence were approximately 5 times larger in motor terminals from presymptomatic mice expressing mutations of human superoxide dismutase I (SOD1) that cause familial amyotrophic lateral sclerosis (SOD1-G85R, which lacks dismutase activity; SOD1-G93A, which retains dismutase activity). Rhodamines 51-60 superoxide dismutase 1 Homo sapiens 210-214 19041851-4 2009 Moreover, expression of P-gp and BCRP was lower in hCMEC/D3 than in human brain microvessels but remain functional as shown by rhodamine 123 efflux assay. Rhodamines 127-136 phosphoglycolate phosphatase Homo sapiens 24-28 19041851-4 2009 Moreover, expression of P-gp and BCRP was lower in hCMEC/D3 than in human brain microvessels but remain functional as shown by rhodamine 123 efflux assay. Rhodamines 127-136 BCR pseudogene 1 Homo sapiens 33-37 19194580-3 2009 These properties are mechanistically ascribed to the transfer from rhodamine spirolactam to the thiazoline-derived open-ring rhodamine via Hg2+ induced desulfurization. Rhodamines 67-76 polycystin 1, transient receptor potential channel interacting pseudogene 2 Homo sapiens 139-142 19174508-7 2009 Compared with WT, stimulation-induced increases in rhodamine-123 fluorescence were approximately 5 times larger in motor terminals from presymptomatic mice expressing mutations of human superoxide dismutase I (SOD1) that cause familial amyotrophic lateral sclerosis (SOD1-G85R, which lacks dismutase activity; SOD1-G93A, which retains dismutase activity). Rhodamines 51-60 superoxide dismutase 1 Homo sapiens 267-271 19174508-7 2009 Compared with WT, stimulation-induced increases in rhodamine-123 fluorescence were approximately 5 times larger in motor terminals from presymptomatic mice expressing mutations of human superoxide dismutase I (SOD1) that cause familial amyotrophic lateral sclerosis (SOD1-G85R, which lacks dismutase activity; SOD1-G93A, which retains dismutase activity). Rhodamines 51-60 superoxide dismutase 1 Homo sapiens 267-271 19120455-8 2009 Because MRP1 was expressed in all the cell lines tested and the efflux of rhodamines in MRP1 over-expressing cells was abolished by NBD-Cl, it appears that rhodamines are excluded from these cells by MRP1. Rhodamines 74-84 ATP binding cassette subfamily C member 1 Homo sapiens 8-12 19120455-8 2009 Because MRP1 was expressed in all the cell lines tested and the efflux of rhodamines in MRP1 over-expressing cells was abolished by NBD-Cl, it appears that rhodamines are excluded from these cells by MRP1. Rhodamines 74-84 ATP binding cassette subfamily C member 1 Homo sapiens 88-92 19120455-8 2009 Because MRP1 was expressed in all the cell lines tested and the efflux of rhodamines in MRP1 over-expressing cells was abolished by NBD-Cl, it appears that rhodamines are excluded from these cells by MRP1. Rhodamines 74-84 ATP binding cassette subfamily C member 1 Homo sapiens 88-92 19120455-8 2009 Because MRP1 was expressed in all the cell lines tested and the efflux of rhodamines in MRP1 over-expressing cells was abolished by NBD-Cl, it appears that rhodamines are excluded from these cells by MRP1. Rhodamines 156-166 ATP binding cassette subfamily C member 1 Homo sapiens 8-12 19120455-8 2009 Because MRP1 was expressed in all the cell lines tested and the efflux of rhodamines in MRP1 over-expressing cells was abolished by NBD-Cl, it appears that rhodamines are excluded from these cells by MRP1. Rhodamines 156-166 ATP binding cassette subfamily C member 1 Homo sapiens 88-92 19120455-8 2009 Because MRP1 was expressed in all the cell lines tested and the efflux of rhodamines in MRP1 over-expressing cells was abolished by NBD-Cl, it appears that rhodamines are excluded from these cells by MRP1. Rhodamines 156-166 ATP binding cassette subfamily C member 1 Homo sapiens 88-92 19120455-11 2009 The innate resistance provided by MRP1 to cells prevents rhodamine dyes, and possibly drugs such as doxorubicin, from achieving equilibration of their concentration in the cytoplasm with their concentration in the external medium. Rhodamines 57-66 ATP binding cassette subfamily C member 1 Homo sapiens 34-38 19232006-2 2009 injection of vasoactive intestinal peptide (VIP) loaded in rhodamine-conjugated liposomes (VIP-Rh-Lip) on experimental autoimmune uveoretinitis (EAU). Rhodamines 59-68 vasoactive intestinal peptide Rattus norvegicus 44-47 19179882-10 2009 Hepatocyte extrusion of rhodamine dye, a measure of MDR1 function, declined only in the TPN with lipid group. Rhodamines 24-33 malic enzyme complex, mitochondrial Mus musculus 52-56 18592293-9 2008 SGLT1 G507C rhodamine fluorescence intensity increased with depolarizing and decreased with hyperpolarizing voltages. Rhodamines 12-21 solute carrier family 5 member 1 Homo sapiens 0-5 19124148-5 2009 The inhibition of efflux activity was measured via the increased rhodamine uptake by mouse lymphoma cells transfected in human MDR1 gene and in human brain capillary endothelial cells. Rhodamines 65-74 ATP binding cassette subfamily B member 1 Homo sapiens 127-131 18845169-7 2008 KB3-1 significantly enhanced the accumulation and retention of a P-gp substrate, rhodamine-123 in the P-gp-expressing MES-SA/DX5 uterine sarcoma cells but not in the P-gp-negative MES-SA cells at non-toxic concentrations of 1 microM and 3 microM. Rhodamines 81-90 ATP binding cassette subfamily B member 1 Homo sapiens 65-69 18845169-7 2008 KB3-1 significantly enhanced the accumulation and retention of a P-gp substrate, rhodamine-123 in the P-gp-expressing MES-SA/DX5 uterine sarcoma cells but not in the P-gp-negative MES-SA cells at non-toxic concentrations of 1 microM and 3 microM. Rhodamines 81-90 ATP binding cassette subfamily B member 1 Homo sapiens 102-106 18845169-7 2008 KB3-1 significantly enhanced the accumulation and retention of a P-gp substrate, rhodamine-123 in the P-gp-expressing MES-SA/DX5 uterine sarcoma cells but not in the P-gp-negative MES-SA cells at non-toxic concentrations of 1 microM and 3 microM. Rhodamines 81-90 ATP binding cassette subfamily B member 1 Homo sapiens 102-106 19031139-10 2008 There was positive correlation between the percentage of Rhodamine 123 low staining cells and positive msi-1 cells in each group (r=0.867, P<0.01). Rhodamines 57-66 musashi RNA-binding protein 1 Mus musculus 103-108 18799096-5 2008 P-gp-mediated transport activity of cells was detected by rhodamine 123 efflux assay. Rhodamines 58-67 ATP binding cassette subfamily B member 1 Homo sapiens 0-4 17941015-8 2008 The in vitro Rhodamine 123 efflux experiment using MDR KB(v200) cells revealed that when cells were pretreated with folate-attached and FG020326-loaded micelles, the P-glycoprotein (P-gp) drug efflux function was significantly inhibited. Rhodamines 13-22 ATP binding cassette subfamily B member 1 Homo sapiens 166-180 18403942-1 2008 OBJECTIVES: The present study was aimed at evaluation of in vivo biliary and renal excretion of rhodamine 123 (Rho123), a P-glycoprotein (P-gp) substrate, in rats during either acute or chronic cholestasis induced by bile duct obstruction (BDO). Rhodamines 96-105 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 122-136 18403942-1 2008 OBJECTIVES: The present study was aimed at evaluation of in vivo biliary and renal excretion of rhodamine 123 (Rho123), a P-glycoprotein (P-gp) substrate, in rats during either acute or chronic cholestasis induced by bile duct obstruction (BDO). Rhodamines 96-105 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 138-142 19881253-5 2009 The uptake of [(3)H]paclitaxel and rhodamine 123 increased by verapamil, a P-gp inhibitor. Rhodamines 35-44 ATP binding cassette subfamily B member 1 Homo sapiens 75-79 20053600-2 2009 P-glycoprotein activity in lymphocytes was measured by the Rhodamine 123 efflux assay using flow cytometry, in the presence and absence of verapamil, a P-glycoprotein inhibitor. Rhodamines 59-68 ATP binding cassette subfamily B member 1 Homo sapiens 0-14 18945821-4 2009 The designed agents were potent inhibitors of rhodamine 123 efflux in cultured cancer cell lines that display high levels of P-gp expression at the cell surface and in transfected cells expressing P-gp. Rhodamines 46-55 ATP binding cassette subfamily B member 1 Homo sapiens 125-129 18945821-4 2009 The designed agents were potent inhibitors of rhodamine 123 efflux in cultured cancer cell lines that display high levels of P-gp expression at the cell surface and in transfected cells expressing P-gp. Rhodamines 46-55 ATP binding cassette subfamily B member 1 Homo sapiens 197-201 19309222-10 2009 Rhodamine retention alone and in the presence of cyclosporine was the lowest in imatinib-resistant K-562R-0.1 cell line, what suggest high PGP activity in this cell line. Rhodamines 0-9 phosphoglycolate phosphatase Homo sapiens 139-142 18559252-3 2008 Because tight dimerization will result in complete energy transfer from donor to acceptor, we have used the same experimental system of fluorescein- and rhodamine-labeled G380R mutants of FGFR3 for the experimental assessment of the proximity FRET corrections using fluorescence lifetime measurements. Rhodamines 153-162 fibroblast growth factor receptor 3 Homo sapiens 188-193 18637679-1 2008 A new chemosensor RF1 that combines a ferrocene unit and a rhodamine block via the linkage of a carbohydrazone binding unit was designed and prepared for the highly selective detection of Hg (2+) in natural water. Rhodamines 59-68 mitochondrial translation release factor 1 Homo sapiens 18-21 18637679-5 2008 Hg (2+)-binding also arouses the absorption of the rhodamine moiety in RF1 significantly with the chromogenic detection limit for Hg (2+) at 50 ppb. Rhodamines 51-60 mitochondrial translation release factor 1 Homo sapiens 71-74 18633498-1 2008 On the basis of fluorescent resonance energy transfer from 1,8-naphthalimide to rhodamine, a fluorophore dyad (FD8) containing rhodamine and a naphthalimide moiety was synthesized as a Cr3+-selective fluorescent probe for monitoring Cr3+ in living cells with ratiometric fluorescent methods. Rhodamines 80-89 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 185-188 18633498-1 2008 On the basis of fluorescent resonance energy transfer from 1,8-naphthalimide to rhodamine, a fluorophore dyad (FD8) containing rhodamine and a naphthalimide moiety was synthesized as a Cr3+-selective fluorescent probe for monitoring Cr3+ in living cells with ratiometric fluorescent methods. Rhodamines 127-136 teratocarcinoma-derived growth factor 1 pseudogene 3 Homo sapiens 185-188 18612518-1 2008 Isotopically substituted rhodamine dyes provide ideal probes for the study of single-molecule surface enhanced Raman scattering (SM-SERS) events through multiple-analyte techniques. Rhodamines 25-34 seryl-tRNA synthetase 2, mitochondrial Homo sapiens 132-136 18489122-3 2008 Here we show that rhodamine-phalloidin binds both Arp2/3 complex and the VCA domain of Arp2/3 complex activator, hWASp, with dissociation equilibrium constants of about 100 nM. Rhodamines 18-27 actin related protein 2 Homo sapiens 50-54 18489122-3 2008 Here we show that rhodamine-phalloidin binds both Arp2/3 complex and the VCA domain of Arp2/3 complex activator, hWASp, with dissociation equilibrium constants of about 100 nM. Rhodamines 18-27 actin related protein 2 Homo sapiens 87-91 18489122-3 2008 Here we show that rhodamine-phalloidin binds both Arp2/3 complex and the VCA domain of Arp2/3 complex activator, hWASp, with dissociation equilibrium constants of about 100 nM. Rhodamines 18-27 WASP actin nucleation promoting factor Homo sapiens 113-118 18205807-5 2008 In the rpd3 Delta and rom2 Delta mutants, the level of PDR5 mRNA and the rate of rhodamine 6G efflux were reduced. Rhodamines 81-90 histone deacetylase RPD3 Saccharomyces cerevisiae S288C 7-11 18205807-5 2008 In the rpd3 Delta and rom2 Delta mutants, the level of PDR5 mRNA and the rate of rhodamine 6G efflux were reduced. Rhodamines 81-90 Rho family guanine nucleotide exchange factor ROM2 Saccharomyces cerevisiae S288C 22-26 18646325-5 2008 Flow cytometry was also used to determine the efflux activity associated with P-gp; with this process, refluxed fluorescent P-gp substrate, rhodamine 123 (Rho123), was determined by the subsequently identified P-gp-positive PBMC subset. Rhodamines 140-149 ATP binding cassette subfamily B member 1 Homo sapiens 78-82 18646325-5 2008 Flow cytometry was also used to determine the efflux activity associated with P-gp; with this process, refluxed fluorescent P-gp substrate, rhodamine 123 (Rho123), was determined by the subsequently identified P-gp-positive PBMC subset. Rhodamines 140-149 ATP binding cassette subfamily B member 1 Homo sapiens 124-128 18646325-5 2008 Flow cytometry was also used to determine the efflux activity associated with P-gp; with this process, refluxed fluorescent P-gp substrate, rhodamine 123 (Rho123), was determined by the subsequently identified P-gp-positive PBMC subset. Rhodamines 140-149 ATP binding cassette subfamily B member 1 Homo sapiens 124-128 18046703-6 2007 Ultraviolet (UV) illumination of the aorta allowed the identification of regions with high macrophage content, while MSR-targeted rhodamine micelles could be detected with fluorescence microscopy and were found to be associated with macrophages. Rhodamines 130-139 macrophage scavenger receptor 1 Mus musculus 117-120 18356296-0 2008 A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5. Rhodamines 45-54 ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C 104-108 18234154-5 2008 CBT-1 completely inhibited rhodamine 123 transport from Pgp-overexpressing cells at a concentration of 1muM. Rhodamines 27-36 succinate dehydrogenase complex subunit D Homo sapiens 0-5 18234154-5 2008 CBT-1 completely inhibited rhodamine 123 transport from Pgp-overexpressing cells at a concentration of 1muM. Rhodamines 27-36 ATP binding cassette subfamily B member 1 Homo sapiens 56-59 18234154-10 2008 Serum levels of CBT-1 in samples obtained from eight patients receiving CBT-1 increased intracellular rhodamine 123 levels in CD56+ cells 2.1- to 5.7-fold in an ex vivo assay. Rhodamines 102-111 succinate dehydrogenase complex subunit D Homo sapiens 16-21 18234154-10 2008 Serum levels of CBT-1 in samples obtained from eight patients receiving CBT-1 increased intracellular rhodamine 123 levels in CD56+ cells 2.1- to 5.7-fold in an ex vivo assay. Rhodamines 102-111 succinate dehydrogenase complex subunit D Homo sapiens 72-77 17647225-10 2008 Based on the rhodamine accumulation study, the increased cytotoxicity is possibly due to the P-gp inhibition by CPGS. Rhodamines 13-22 ATP binding cassette subfamily B member 1 Homo sapiens 93-97 18221354-10 2008 Intraperitoneal administration of monoclonal antibodies to CD11b (rat IgG2b) to C3H/HeN mice inhibited UVB-induced oxidative stress generated by both epidermal and dermal cells as is evident by relative fluorescence intensity of oxidized rhodamine. Rhodamines 238-247 integrin alpha M Mus musculus 59-64 18221354-10 2008 Intraperitoneal administration of monoclonal antibodies to CD11b (rat IgG2b) to C3H/HeN mice inhibited UVB-induced oxidative stress generated by both epidermal and dermal cells as is evident by relative fluorescence intensity of oxidized rhodamine. Rhodamines 238-247 immunoglobulin heavy constant gamma 2B Mus musculus 70-75 18302483-4 2008 After 12 days, MDR1 expression was determined by the rhodamine efflux assay. Rhodamines 53-62 ATP binding cassette subfamily B member 1 Homo sapiens 15-19 18059369-5 2008 Rhodamine-labeled DNA nanoparticles colocalize with nucleolin on the cell surface, as well as in the cytoplasm and nucleus, but not with transferrin or markers of early endosome or lysosome following cellular uptake. Rhodamines 0-9 nucleolin Homo sapiens 52-61 17942408-4 2007 Rhodamine-phalloidin staining revealed increase stress fiber formation in vascular smooth muscle cells of profilin 1 compared with 88R/L and control. Rhodamines 0-9 profilin 1 Mus musculus 106-116 18451986-0 2007 Ocular and systemic bio-distribution of rhodamine-conjugated liposomes loaded with VIP injected into the vitreous of Lewis rats. Rhodamines 40-49 vasoactive intestinal peptide Rattus norvegicus 83-86 18451986-2 2007 The purpose of the present study was to define the biodistribution of rhodamine-conjugated liposomes loaded with vasoactive intestinal peptide (VIP), an immunosuppressive neuropeptide, following their intravitreal (IVT) injection in normal rats. Rhodamines 70-79 vasoactive intestinal peptide Rattus norvegicus 144-147 17873103-4 2008 Fluorescent-labeled microspheres composed of poly lactic-coglycolic acid (PLGA) were loaded with rhodamine-labeled PF-4/CTF and formulated to release their contents over time. Rhodamines 97-106 platelet factor 4 Homo sapiens 115-119 17964793-2 2008 Herein, we describe the development of a novel screen for PAD4 inhibitors that is based on a PAD4-targeted Activity-Based Protein Profiling reagent, denoted Rhodamine-conjugated F-Amidine (RFA). Rhodamines 157-166 peptidyl arginine deiminase 4 Homo sapiens 58-62 17964793-2 2008 Herein, we describe the development of a novel screen for PAD4 inhibitors that is based on a PAD4-targeted Activity-Based Protein Profiling reagent, denoted Rhodamine-conjugated F-Amidine (RFA). Rhodamines 157-166 peptidyl arginine deiminase 4 Homo sapiens 93-97 17950691-6 2008 273 (1998) 12612-12622], we show that Yor1p also confers resistance to rhodamine 6G and to doxorubicin. Rhodamines 71-80 ATP-binding cassette transporter YOR1 Saccharomyces cerevisiae S288C 38-43 18989812-9 2008 The PLA(2) and Mel activities were measured indirectly by changes in turbidity at 400(n m), rhodamine leak-out, and hemolysis. Rhodamines 92-101 phospholipase A2 group IB Homo sapiens 4-10 18369935-6 2008 Fusion of labeled v-SNARE liposomes with unlabeled t-SNARE liposomes increases the distance between NBD and rhodamine, increasing the NBD fluorescence. Rhodamines 108-117 vesicle transport through interaction with t-SNAREs 1B Homo sapiens 18-25 18234965-9 2008 Silencing the expression of the DNA binding subunit of NF-kappaB, p50, by small interfering RNA vector resulted in a decrease of MDR1 function by rhodamine 123 efflux assay in T167 cells exposed to 2 Gy. Rhodamines 146-155 nuclear factor kappa B subunit 1 Homo sapiens 66-69 18234965-9 2008 Silencing the expression of the DNA binding subunit of NF-kappaB, p50, by small interfering RNA vector resulted in a decrease of MDR1 function by rhodamine 123 efflux assay in T167 cells exposed to 2 Gy. Rhodamines 146-155 ATP binding cassette subfamily B member 1 Homo sapiens 129-133