PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
26415731-9	2015	Both PaCO2 and PaO2 had an independent U-shaped relationship with hospital mortality and after adjustment for confounders, hypocapnia and hypoxia were significant predictors of hospital mortality: OR 1.37 (95 % CI 1.17-1.61) and OR 1.34 (95 % CI 1.08-1.66).	paco2	5-10	olfactory receptor family 13 subfamily G member 1	Homo sapiens	197-204
27821836-4	2016	RESULTS Hemodynamic indexes and PaO2/PaCO2 in group L1.0 showed no differences at each time point (all P>0.05).	paco2	37-42	immunoglobulin kappa variable 3-7 (non-functional)	Homo sapiens	52-56
26422449-8	2016	dCap was in correlation (r = 0.70, P < 0.001) but with less than adequate agreement (mean difference +- SD of the differences: -11.7 +- 10.3 mmHg) with PaCO2 .	paco2	155-160	CAP	Drosophila melanogaster	0-4
26422449-12	2016	Area under the receiver operating curves (ROC) for dCap to detect high (>60 mmHg) or low (<30 mmHg) PaCO2 was 0.83 (CI: 0.76-0.90) and 0.88 (CI: 0.79-0.97), respectively; P < 0.001.	paco2	106-111	CAP	Drosophila melanogaster	51-55
26422449-13	2016	CONCLUSIONS: Our prospective study suggests that continuous dCap in infants ventilated with HFV may be helpful for trends and alarm for unsafe levels of PaCO2 .	paco2	153-158	CAP	Drosophila melanogaster	60-64
26422449-2	2016	Our aim was to assess the diagnostic accuracy (correlation, agreement, and trending) of continuous distal capnography (dCap) with PaCO2 in infants ventilated with HFV.	paco2	130-135	CAP	Drosophila melanogaster	119-123
26415731-9	2015	Both PaCO2 and PaO2 had an independent U-shaped relationship with hospital mortality and after adjustment for confounders, hypocapnia and hypoxia were significant predictors of hospital mortality: OR 1.37 (95 % CI 1.17-1.61) and OR 1.34 (95 % CI 1.08-1.66).	paco2	5-10	olfactory receptor family 6 subfamily F member 1	Homo sapiens	229-236
26159014-10	2015	Plasma levels of Fg and D-D levels were negatively correlated with PaO2 (r = -0.493, r = -0.438, P < 0.01) before treatment, and also negatively correlated with PaO2 (r = -0.452, r = -0.325, P < 0.01, P < 0.05) after treatment, but they were not significantly correlated with PaCO2 before and after treatment (P >0.05).	paco2	285-290	fibrinogen beta chain	Homo sapiens	17-19
25873428-2	2015	Until now, the interrelationship of PaCO2-induced changes in CBF, CVR, CPPe, ZFP, and RAP is not fully understood.	paco2	36-41	LDL receptor related protein associated protein 1	Homo sapiens	86-89
24572450-5	2014	CSA primarily results from a fall in PaCO2 to a level below the apnea threshold during sleep through the reflex inhibition of central respiratory drive.	paco2	37-42	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	0-3
25253897-9	2015	CCL-18 negatively correlated with diffusion capacity of carbon monoxide (DLCO), arterial oxygen (PaO2) and mean arterial carbon dioxide (PaCO2) (P < 0.05) and CRP negatively correlated with DLCO, PaO2, sleep SaO2 and oxygen uptake (VO2) during exercise (P < 0.05).	paco2	137-142	C-C motif chemokine ligand 18	Homo sapiens	0-6
25580140-10	2014	CONCLUSION: Elevated serum GDF-15 level and PaCO2>37 mm Hg were found to predict an adverse outcome independently in patients with COPD exacerbation, suggesting the possibility that serum GDF-15 could be used as a prognostic biomarker of COPD exacerbation.	paco2	44-49	growth differentiation factor 15	Homo sapiens	191-197
25641242-6	2015	The vasopressin group received fewer doses of surfactant (P < .05), had lower PaCO2 values (P < .05), and were not tachycardic (P < .001) during vasopressin administration, compared with the dopamine group.	paco2	81-86	arginine vasopressin	Homo sapiens	4-15
21567113-6	2011	RESULTS: Compared to V(MASK), n-CPAP at 10 cmH2O delivered via a helmet, increased PaO2/FiO2 and decreased dyspnea in both B(L) and U(L); furthermore, it reduced the respiratory rate and brought PaCO2 up to normal in B(L) only.	paco2	195-200	centromere protein J	Homo sapiens	32-36
23596488-7	2013	The plasma D-dimer and FIB levels had significantly positive correlations with the partial pressure of CO2 (PaCO2) and negative correlations with the partial pressure of O2 (PaO2) in the patients with AECOPD combined with respiratory failure.	paco2	108-113	fibrinogen beta chain	Homo sapiens	23-26
24463132-1	2014	OBJECTIVE: To investigate the correlation between arterial partial pressure of CO2 (PaCO2) and end expiratory tidal partial pressure of CO2 (Pet-CO2) in morbidly obese patients during anesthesia for laparoscopic gastric bypass surgery.	paco2	84-89	complement C2	Homo sapiens	141-148
24463132-6	2014	At a moderate pressure of CO2 pneumoperitoneum (16 mmHg), the level of correlation between PaCO2 and Pet-CO2 at T1, T2, and T3 differed from that before and after post-pneumoperitoneum.	paco2	91-96	complement C2	Homo sapiens	101-108
20223999-9	2010	The reduction in ScO2 after administration of phenylephrine was attenuated during low-intensity exercise (-5%, P<0.001) and abolished during high-intensity exercise (-3%, P=not significant), where PaCO2 decreased 7% (P<0.05) and CMRO2 increased 17% (P<0.05).	paco2	200-205	synthesis of cytochrome C oxidase 2	Homo sapiens	17-21
19909502-7	2009	Both PaO2 and PaCO2 presented with different progression slopes within specific CFTR genotypes.	paco2	14-19	CF transmembrane conductance regulator	Homo sapiens	80-84
16761421-7	2006	RESULTS: The ARDS rats treated with SST, Octreotide and dexamethasone showed mitigation of inflammatory response in the lungs, improvement in lung ventilation, reduction of pulmonary coefficient (-13%-15%), increase in PaO2 level (+75%-84%), decrease in PaCO2 level (-17%-22%), and restoration of pH value to normal in plasma, when compared with the rats of ARDS group.	paco2	254-259	somatostatin	Rattus norvegicus	36-39
19388311-3	2008	CO2 manipulation plays a basic role in the management of intracranial hypertension; CO2 reactivity (CO2R) defines the changes in CBF in response to changes in PaCO2.	paco2	159-164	CCAAT enhancer binding protein zeta	Homo sapiens	129-132
18421557-4	2008	There was a correlation between differences in PaCO2 and arterial oxygen saturation during CPAP (R = -0.97, p < 0.01, n = 6).	paco2	47-52	centromere protein J	Homo sapiens	91-95
17386191-13	2007	With combined CPAP of 3 cm H20 and PSV of 12 cm H20, PaCO2 was reduced from a baseline value of 41.2 (1.5) mm Hg to 38.7 (1.9) mm Hg.	paco2	53-58	centromere protein J	Homo sapiens	14-18
16251267-7	2006	During triazolam-induced stage 2 sleep, absolute CBF of the cerebral white matter correlated more strongly to both MAP and Paco2 than during placebo sleep and also correlated more strongly to both MAP and Paco2 than absolute CBF of the occipital cortex.	paco2	123-128	CCAAT enhancer binding protein zeta	Homo sapiens	49-52
16251267-7	2006	During triazolam-induced stage 2 sleep, absolute CBF of the cerebral white matter correlated more strongly to both MAP and Paco2 than during placebo sleep and also correlated more strongly to both MAP and Paco2 than absolute CBF of the occipital cortex.	paco2	205-210	CCAAT enhancer binding protein zeta	Homo sapiens	49-52
16251267-9	2006	During triazolam-induced stage 2, the cerebral white matter may receive a modulated CBF regulation having the strengthened relationship of Paco2 to CBF and, more locally, the frontal white matter may depend precariously on CBF regulation.	paco2	139-144	CCAAT enhancer binding protein zeta	Homo sapiens	84-87
16251267-9	2006	During triazolam-induced stage 2, the cerebral white matter may receive a modulated CBF regulation having the strengthened relationship of Paco2 to CBF and, more locally, the frontal white matter may depend precariously on CBF regulation.	paco2	139-144	CCAAT enhancer binding protein zeta	Homo sapiens	148-151
16251267-9	2006	During triazolam-induced stage 2, the cerebral white matter may receive a modulated CBF regulation having the strengthened relationship of Paco2 to CBF and, more locally, the frontal white matter may depend precariously on CBF regulation.	paco2	139-144	CCAAT enhancer binding protein zeta	Homo sapiens	148-151
12212168-3	2000	The plasma NSE activity from the patients with pulmonary encephalopathy were negatively correlated with the PaO2 and were positively correlated with PaCO2.	paco2	149-154	enolase 2	Homo sapiens	11-14
15871446-6	2005	The serum soluble CTLA-4 concentrations in the asthmatics statistically correlated with forced expiratory volume in one second (r = -0.410, p = 0.027), percentage of predicted peak expiratory flow (r = -0.449, p = 0.015), and PaCO2 (r = 0.555, p = 0.002), respectively.	paco2	226-231	cytotoxic T-lymphocyte associated protein 4	Homo sapiens	18-24
12006797-3	2002	DESIGN: Prospective evaluation of the correlation between transcutaneous CO2 (TC(CO2)) and PaCO2 values.	paco2	91-96	complement C2	Homo sapiens	73-76
12006797-12	2002	CONCLUSIONS: TC(CO2) monitoring provides an accurate and clinically acceptable estimate of PaCO2 over a wide range of CO2 values in pediatric patients during high-frequency oscillatory ventilation.	paco2	91-96	complement C2	Homo sapiens	16-19
11300380-8	2001	RESULTS: The pHi and PCO2-gap, the difference between PrCO2 and arterial CO2 tension (PaCO2), showed a transient decrease and an increase after CPB, respectively.	paco2	86-91	glucose-6-phosphate isomerase	Homo sapiens	13-16
12134440-7	2001	As compared with patients with low ANP levels, patients with high ANP levels were older and more obese, more frequently had concomitant COPD, lower VC and FEV1, higher daytime PaCO2 and lower PaO2; most of them had peripheral edema.	paco2	176-181	natriuretic peptide A	Homo sapiens	66-69
11817709-9	2001	BAL IGF-I and IGFBP-3 concentrations were significantly related to inspiratory vital capacity (IVC) and carbon dioxide partial pressure (PaCO2): the higher the value of IVC and the lower the value of PaCO2, the higher the level of IGF-I and IGFBP-3.	paco2	137-142	insulin like growth factor 1	Homo sapiens	4-9
11817709-9	2001	BAL IGF-I and IGFBP-3 concentrations were significantly related to inspiratory vital capacity (IVC) and carbon dioxide partial pressure (PaCO2): the higher the value of IVC and the lower the value of PaCO2, the higher the level of IGF-I and IGFBP-3.	paco2	137-142	insulin like growth factor binding protein 3	Homo sapiens	14-21
11817709-9	2001	BAL IGF-I and IGFBP-3 concentrations were significantly related to inspiratory vital capacity (IVC) and carbon dioxide partial pressure (PaCO2): the higher the value of IVC and the lower the value of PaCO2, the higher the level of IGF-I and IGFBP-3.	paco2	200-205	insulin like growth factor 1	Homo sapiens	4-9
11817709-9	2001	BAL IGF-I and IGFBP-3 concentrations were significantly related to inspiratory vital capacity (IVC) and carbon dioxide partial pressure (PaCO2): the higher the value of IVC and the lower the value of PaCO2, the higher the level of IGF-I and IGFBP-3.	paco2	200-205	insulin like growth factor binding protein 3	Homo sapiens	14-21
10589941-12	1999	From the anhepatic to the reperfusion phase, the CBF increased 7% (0 to 26) for each mm Hg concomitant increase in PaCO2.	paco2	115-120	CCAAT enhancer binding protein zeta	Homo sapiens	49-52
10846438-1	2000	We calculated reference values for arterial blood gases at different altitudes in Mexico assuming that sea level PaCO2 is 40 Torr, and in Mexico City (2.24 km.	paco2	113-118	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	103-106
10846438-12	2000	In conclusion, according to reference values in Mexico City, PaCO2 decreases about 4 Torr per km of altitude above the sea level.	paco2	61-66	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	119-122
10201680-10	1999	RESULTS: During CPR without IPPV, CPAP decreased PaCO2 (55+/-28 vs. 100+/-16 mmHg) and increased SaO2 (0.86+/-0.19 vs. 0.50+/-0.18%; P < 0.001).	paco2	49-54	centromere protein J	Homo sapiens	34-38
10541249-4	1999	The authors report on three patients with severe head injury with otherwise normal cerebral perfusion pressure, SaO2, PaCO2, and controlled intracranial pressure (ICP), in whom a secondary excessive increase in serum S-100B was observed.	paco2	118-123	S100 calcium binding protein B	Homo sapiens	217-223
11715416-7	1999	mPAP in hypercapnia group was (2.0 +/- 0.4) kPa, PaCO2 (7.4 +/- 0.4) kPa, T1/2 (150 +/- 23) min, LPO (8.8 +/- 2.0) nmol/ml, SOD (682 +/- 341) U/g Hb1 and water content was (78.8 +/- 1.8)% in lung and (76.04 +/- 1.07)% in muscular tissues.	paco2	49-54	phospholipid phosphatase 1	Mus musculus	0-4
9089892-3	1997	Significant simple correlations (P < 0.01) of log(s-EPO) were obtained with PaO2 (r = -0.66), PaCO2 (r = 0.59), HCO3- (r = 0.67), BE (r = 0.71) and SaO2 (r = -0.77).	paco2	97-102	erythropoietin	Homo sapiens	55-58
10757682-3	1999	PaCO2 in HOT was significantly higher than that of non-HOT (44.8 Torr vs 40.0 Torr).	paco2	0-5	alcohol dehydrogenase iron containing 1	Homo sapiens	9-12
8607311-8	1995	The observed changes in pHi and PtonCO2 were due to changes in pHa and in PaCO2 and not a sign of gastric mucosal ischemia.	paco2	74-79	glucose-6-phosphate isomerase	Homo sapiens	24-27
8991475-5	1996	Inspiratory pressure support of 15 cmH2O reduced respiratory rate to less than 30 breaths/min, improved paO2 and reduced elevated paCO2 towards normal within 3 hours.	paco2	130-135	troponin T2, cardiac type	Homo sapiens	35-39
8990886-15	1996	Therefore we suggest that relatively slow rewarming, higher PaCO2, and more acidic pH strategies were advantageous for preventing desaturation during and after rewarming in RCP.	paco2	60-65	CGRP receptor component	Homo sapiens	173-176
8741473-6	1996	In most patients without nasal obstruction breathing through the nostril, PET(CO2) determined by selective nasal sampling was closer to PaCO2 than those by oral or nasal/oral sampling.	paco2	136-141	complement C2	Homo sapiens	74-81
7861600-2	1994	The relationship between Vm and mean arterial blood pressure (mBP) showed a linear regression in each constant level of PaCO2.	paco2	120-125	myelin basic protein	Mus musculus	62-65
7665405-4	1995	O2 breathing caused CBF to fall by 30% in group 1, whereas CBF rose linearly with the PaCO2 increase and pH decline in group 2.	paco2	86-91	CCAAT/enhancer binding protein zeta	Rattus norvegicus	59-62
8599281-3	1995	Contrary to the original impression, we concluded that a very low PaCO2 of 13 mmHg towards the end of CPB was the most likely cause of his damage.	paco2	66-71	carboxypeptidase B1	Homo sapiens	102-105
7549227-7	1994	Ibuprofen also stabilized thrombin-induced impairments in PaO2, PaCO2 and pH.	paco2	64-69	coagulation factor II	Rattus norvegicus	26-34
7768140-4	1994	A significant positive correlation was found between ET-1 level and PaCO2.	paco2	68-73	endothelin 1	Homo sapiens	53-57
7490017-3	1995	There was a positive correlation between elevated levels of serum MBP and carbon dioxide partial pressure (PaCO2).	paco2	107-112	myelin basic protein	Homo sapiens	66-69
7609296-3	1995	The relationship between Vm and mBP showed a linear regression at each constant level of PaCO2.	paco2	89-94	myelin basic protein	Mus musculus	32-35
7571166-3	1995	During infusion of thrombin, mean pulmonary artery pressure rose and mean systemic artery pressure fell, PaO2 decreased progressively and there was a continuous rise in pH and PaCO2.	paco2	176-181	coagulation factor II	Rattus norvegicus	19-27
7955280-10	1994	In group 1 (n = 8), PVR increased in direct correlation with PICO2 and PACO2, and inversely with respect to pH (r = .98, .74, and .83, respectively).	paco2	71-76	PVR cell adhesion molecule	Homo sapiens	20-23
8176860-0	1994	[A study on evaluation of CBF measurement based on microsphere model with N-isopropyl-p-[123I]iodoamphetamine (IMP) and SPECT--its correction with the value of PaCO2].	paco2	160-165	CCAAT enhancer binding protein zeta	Homo sapiens	26-29
8085448-9	1994	There was a significantly higher PaCO2 in the N-CPAP group than in the ventilator group.	paco2	33-38	centromere protein J	Homo sapiens	48-52
8085448-11	1994	A delayed decline in PaCO2 until 48 hours after surfactant instillation in the N-CPAP group was noted.	paco2	21-26	centromere protein J	Homo sapiens	81-85
7839786-8	1994	With regard to CO2 responsiveness, an 8.85% increase in rCBF was demonstrated for a Paco2 elevation of 1 kPa before midazolam administration, compared with a 7.47% increase after midazolam administration.	paco2	84-89	CCAAT/enhancer binding protein zeta	Rattus norvegicus	56-60
8176860-8	1994	Comparing with the control state with normal breathing, we calculated the rate of change of mean CBF between the state with normal breathing and the state with hyperventilation that was 1.02 ml/100 g/min/mmHg PaCO2.	paco2	209-214	CCAAT enhancer binding protein zeta	Homo sapiens	97-100
8176860-10	1994	When compared CBF values with loading studies or certain therapies, the correction of CBF with the rate of change of PaCO2 is one of the very important factors to be considered.	paco2	117-122	CCAAT enhancer binding protein zeta	Homo sapiens	14-17
8176860-10	1994	When compared CBF values with loading studies or certain therapies, the correction of CBF with the rate of change of PaCO2 is one of the very important factors to be considered.	paco2	117-122	CCAAT enhancer binding protein zeta	Homo sapiens	86-89
8151742-2	1993	The patients with chronic pulmonary heart disease accompanied by carbon dioxide retention (PaCO2 > 6.67 kPa) have a higher level of PAF in blood (0.75 +/- 0.27 microgram/ml) than those who have no carbon dioxide retention (PaCO2 < 6.67 kPa, PAF 0.41 +/- 0.25 microgram/ml) and those in the normal control group (0.45 +/- 0.20 microgram/ml), with P < 0.05 in all.	paco2	91-96	PCNA clamp associated factor	Homo sapiens	135-138
8164325-7	1994	Although PaCO2 did not change during 8 hours in control and 1:2 PEEP 5 groups, PaCO2 decreased slightly with 4 or 5 hours after RDS was induced in 3:1 IRV and 2:1 PEEP 5 groups.	paco2	79-84	peripherin 2	Canis lupus familiaris	128-131
7923434-4	1993	It was demonstrated that ET-1 correlated negatively to PaO2 and PH and correlated positively to PaCO2 and blood creatinine.	paco2	96-101	endothelin 1	Homo sapiens	25-29
8478412-4	1993	The reaction of rCBF to hypercapnia (PaCO2 from 30.5 +/- 1.8 to 61.3 +/- 5.8 mm Hg by adding CO2 to the inspiratory gas) was 2.9 +/- 1.4%/mm Hg, and the reaction of rCBF to H+ (superfusion of acidic aCSF, pH 7.07 +/- 0.05) was 101.7 +/- 24.7%/pH unit.	paco2	37-42	CCAAT/enhancer binding protein zeta	Rattus norvegicus	16-20
8478412-6	1993	After 30 min of L-NA superfusion, rCBF was reduced to 80.1 +/- 6.5% of baseline, and the rCBF responses to hypercapnia (PaCO2 from 30.9 +/- 2.9 to 58.8 +/- 7.7 mm Hg) and extracellular acidosis (aCSF pH 7.08 +/- 0.06) were reduced to 0.8 +/- 1.1%/mm Hg and 10.1 +/- 23.0%/pH unit, respectively (both p < 0.001).	paco2	120-125	CCAAT/enhancer binding protein zeta	Rattus norvegicus	89-93
8151742-2	1993	The patients with chronic pulmonary heart disease accompanied by carbon dioxide retention (PaCO2 > 6.67 kPa) have a higher level of PAF in blood (0.75 +/- 0.27 microgram/ml) than those who have no carbon dioxide retention (PaCO2 < 6.67 kPa, PAF 0.41 +/- 0.25 microgram/ml) and those in the normal control group (0.45 +/- 0.20 microgram/ml), with P < 0.05 in all.	paco2	91-96	PCNA clamp associated factor	Homo sapiens	247-250
1786951-13	1991	HCT would be elevated when PaO2 was below 8 kPa (60 mmHg) and the HCT, eta 0.512, eta", eta" increased significantly (P less than 0.05-0.01) when PaCO2 was over 6.65 kPa (50 mmHg).	paco2	146-151	endothelin receptor type A	Homo sapiens	71-74
1733204-10	1992	Dopamine 10 micrograms.kg-1.min-1 led to a progressive decrease in fetal arterial pH and an increase in PaCO2, which may have been related to similar changes in the ewe.	paco2	104-109	CD59 molecule (CD59 blood group)	Homo sapiens	28-33
1928771-3	1991	In this study we have shown that TCI also depends upon arterial carbon dioxide tension (PaCO2).	paco2	88-93	latexin	Homo sapiens	33-36
1928771-5	1991	For a 45 degrees C PtcO2 sensor, the mean TCI during normocapnia was 0.78, whereas during hyperventilation (PaCO2 = 20 mmHg) the mean TCI was reduced 65%, to 0.27.	paco2	108-113	latexin	Homo sapiens	134-137
1928771-9	1991	For a 44 degrees C sensor on the chest, the mean TCI decreased from 0.77 at normocapnia to 0.60 at a PaCO2 of 17 mmHg, a 22% change.	paco2	101-106	latexin	Homo sapiens	49-52
1618940-6	1992	The rCBF response to hypercapnia (PaCO2 50 mm Hg), however, was symmetrical and robust.	paco2	34-39	CCAAT/enhancer binding protein zeta	Rattus norvegicus	4-8
1488580-6	1992	The PaCO2 found was much lower than that reported for native Peruvians in the Andes who have a mean PaCO2 of 37.8 Torr at an altitude of 2390 m, and a mean PaCO2 of 33.0 Torr only at 4860 m above the sea level.	paco2	4-9	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	200-203
1786951-13	1991	HCT would be elevated when PaO2 was below 8 kPa (60 mmHg) and the HCT, eta 0.512, eta", eta" increased significantly (P less than 0.05-0.01) when PaCO2 was over 6.65 kPa (50 mmHg).	paco2	146-151	endothelin receptor type A	Homo sapiens	82-85
1786951-13	1991	HCT would be elevated when PaO2 was below 8 kPa (60 mmHg) and the HCT, eta 0.512, eta", eta" increased significantly (P less than 0.05-0.01) when PaCO2 was over 6.65 kPa (50 mmHg).	paco2	146-151	endothelin receptor type A	Homo sapiens	82-85
1786951-14	1991	There was a positive linear correlation between eta 0.512 and PaCO2.	paco2	62-67	endothelin receptor type A	Homo sapiens	48-51
1893666-9	1991	The multivariate stepwise regression analysis indicated only "the interval between 2 measurements" to have a significant effect on reduction of mCBF, although in addition to the interval (p less than 0.05), infarct-size (p less than 0.01) and change in PaCO2 (p less than 0.05) were suggested to be possible factors by single regression analysis.	paco2	253-258	CCAAT/enhancer binding protein zeta	Mus musculus	144-148
3108270-1	1987	In chloralose-urethanized cats, vasoactive intestinal peptide (VIP), applied by superfusion in steady-state concentration (10(-10)-10(-6) M) onto cortical vessels in situ resulted in a rapid concentration-dependent vasodilatation in vessels that were mildly constricted by prostaglandin F2 alpha (PGF2 alpha) (5 X 10(-5) M) or hypocarbia (PaCO2 = 26).	paco2	339-344	vasoactive intestinal peptide	Felis catus	63-66
2129131-9	1990	CBF = 2.54 x PaCO2-53.0, r = 0.59, n = 131 The autoregulation of CBF was evaluated in 7 patients, and in 2 patients, the autoregulation of CBF was abolished.	paco2	13-18	CCAAT enhancer binding protein zeta	Homo sapiens	0-7
2114660-7	1990	Ventilatory control of PaCO2 during acute lowering of osmolality may be related to a central inter-action between osmolality and the renin-angiotensin system.	paco2	23-28	renin	Canis lupus familiaris	133-138
2109496-6	1990	Even moderate CPAP induced alveolar hyperventilation with marked reduction in arterial PCO2 (PaCO2) when breathing air.	paco2	93-98	centromere protein J	Homo sapiens	14-18
2109496-7	1990	With increasing fraction of CO2 in the inspiratory gas, the difference in PaCO2 between CPAP and no CPAP disappeared.	paco2	74-79	centromere protein J	Homo sapiens	88-92
2109496-7	1990	With increasing fraction of CO2 in the inspiratory gas, the difference in PaCO2 between CPAP and no CPAP disappeared.	paco2	74-79	centromere protein J	Homo sapiens	100-104
2109496-11	1990	We conclude that CPAP, CNAP and PEEP induce active ventilatory responses in man and that strong mechanisms are involved during CPAP since PaCO2 is markedly reduced.	paco2	138-143	centromere protein J	Homo sapiens	17-21
2109496-11	1990	We conclude that CPAP, CNAP and PEEP induce active ventilatory responses in man and that strong mechanisms are involved during CPAP since PaCO2 is markedly reduced.	paco2	138-143	centromere protein J	Homo sapiens	127-131
2406899-7	1990	Increases in heart rate, respiratory rate, cardiac index, PaCO2 and oxygen delivery can therefore be expected during weaning from mechanical ventilation to spontaneous breathing with CPAP.	paco2	58-63	centromere protein J	Homo sapiens	183-187
2364288-3	1990	The pHi decreased significantly when the paCO2 was increased by hypercapnia.	paco2	41-46	glucose-6-phosphate isomerase	Rattus norvegicus	4-7
2499711-1	1989	During mouthpiece respiration of Xe-133 for a measurement of regional cerebral blood flow (rCBF), the breathing pattern of patients fluctuated and it caused a change of end-tidal CO2 concentration that had an excellent correlation with PaCO2 in patient without respiratory disease.	paco2	236-241	CCAAT/enhancer binding protein zeta	Rattus norvegicus	91-95
2140252-4	1990	Plasma immunoreactive ANF concentrations were 196 +/- 50 pg/ml during O2 breathing and were positively related to transmural pulmonary arterial wedge pressure (tPpaw, r = 0.90, p less than 0.001) and to PaCO2 (r = 0.57, p less than 0.02).	paco2	203-208	natriuretic peptide A	Homo sapiens	22-25
2483984-2	1989	It was showed: (1) Fn, alpha 2-MG. AT-III activity were considerably decreased in COPD, when compare with that of controls; (2) there is a negative correlation between the value of PaCO2, r = -0.719, P less than 0.01.	paco2	181-186	serpin family C member 1	Homo sapiens	35-41
2632032-4	1989	In severe type the ratio of branched chain amino acid to aromatic amino acid (BACC/AAA) was significantly lower than normal (P less than 0.01) and there was significant negative correlation between PaCO2 and BCAA/AAA (r = -0.49 P less than 0.05).	paco2	198-203	AT-rich interaction domain 4B	Homo sapiens	208-212
2696724-3	1989	It was shown that there was a positive correlation between the levels of serum and urine beta 2-MG and PaCO2 and a negative correlation between the levels of serum and urine beta 2-MG and PaO2.	paco2	103-108	beta-2-microglobulin	Homo sapiens	89-98
3205605-11	1988	Despite the increased tidal volume, PVR increased to 53 +/- 35 Hg/liter/min when PaCO2 returned to 44 +/- 5 mm Hg.	paco2	81-86	PVR cell adhesion molecule	Homo sapiens	36-39
2518395-0	1989	Effect of PaCO2 and haemoglobin concentration on day to day variation of CBF in preterm neonates.	paco2	10-15	CCAAT enhancer binding protein zeta	Homo sapiens	73-76
2518395-3	1989	The intra-individual variation of CBF infinity was positively related to changes in PaCO2 (p = 0.0004) and inversely related to changes in Hgb (p = 0.029).	paco2	84-89	CCAAT enhancer binding protein zeta	Homo sapiens	34-37
2518395-6	1989	It is concluded that PaCO2 and Hgb have the expected effect on CBF infinity in preterm neonates even during respiratory distress shortly after birth.	paco2	21-26	CCAAT enhancer binding protein zeta	Homo sapiens	63-66
3441903-3	1987	Thrombin infusion resulted in pulmonary hypertension and increased arterial CO2 tension (PaCO2) and dead space ventilation (VD/VT).	paco2	89-94	prothrombin	Oryctolagus cuniculus	0-8
2835133-6	1987	The effect of AVP on PaCO2 was more variable, showing a transient decrease at +5 min after injection in the two oldest groups of fetuses.	paco2	21-26	vasopressin-neurophysin 2-copeptin	Ovis aries	14-17
6812015-3	1981	Moderate lowering of PaCO2 to 2.5 kPa induced in all animals a homogeneous decrease of rCBF in corresponding areas of the right and left hemisphere.	paco2	21-26	CCAAT/enhancer binding protein zeta	Rattus norvegicus	87-91
3101517-3	1987	Asphyxia [arterial O2 partial pressure (PaO2) = 40-50 Torr, arterial CO2 partial pressure (PaCO2) = 60-80 Torr) increases plasma lysine vasopressin (LVP) from 2.2 +/- 0.8 to 52.4 +/- 15.0 microU/ml.	paco2	91-96	vasopressin	Sus scrofa	136-147
3764954-5	1986	This was due, in part, to the effect of individual variations in PaCO2 on rCBF, but other uncontrolled factors, such as intracranial pressure, may have had influences.	paco2	65-70	CCAAT/enhancer binding protein zeta	Rattus norvegicus	74-78
3083850-3	1986	In five patients, endobronchial insufflation of oxygen 0.5 litre kg-1 min-1 caused approximately a 30% decrease in the increase in PaCO2 compared with apnoeic oxygenation (P less than 0.05) during a period of 6 min.	paco2	131-136	CD59 molecule (CD59 blood group)	Homo sapiens	70-75
3082847-6	1986	With a progressively more acid pHa at the two higher work loads in normal ponies, delta PaCO2 was 7.3 and 7.8 Torr by 90 s and 9.9 and 11.4 Torr by 6 min, respectively (P less than 0.05).	paco2	88-93	lamin B receptor	Homo sapiens	31-34
4055925-4	1985	Complete neurologic and metabolic recovery was observed in these animals, despite and average decrease in pHi of 0.63 +/- 0.02 pH unit during supercarbia episodes that raised PaCO2 to 490 +/- 80 mm Hg.	paco2	175-180	glucose-6-phosphate isomerase	Rattus norvegicus	106-109
4026049-5	1985	Hypercapnia (PaCO2, 85 mmHg) reduced Pdi by 10% at low and high frequencies of stimulation.	paco2	13-18	peptidyl arginine deiminase 1	Homo sapiens	37-40
3922012-4	1985	Neonatal treatment with capsaicin or acute vagotomy also produced adult animals whose basal PaCO2 was elevated and whose respiratory response to TRH was greater than that seen in control rats with lower PaCO2 values.	paco2	203-208	thyrotropin releasing hormone	Rattus norvegicus	145-148
3441903-8	1987	Treatment with forskolin or dipyridamole reversed thrombin-induced changes in pulmonary artery pressure, PaCO2, VD/VT and systemic oxygenation.	paco2	105-110	prothrombin	Oryctolagus cuniculus	50-58
3932317-9	1985	The data suggest that during CO2 inhalation in CBD ponies a hilar-innervated mechanism influences PaCO2 by reducing physiological dead space to increase alveolar ventilation.	paco2	98-103	opsin 1, medium wave sensitive	Homo sapiens	47-50
4014872-7	1985	The Pdi correlated with PaO2 (r = 0.66) and with PaCO2 (r = -0.76; p less than 0.05).	paco2	49-54	peptidyl arginine deiminase 1	Homo sapiens	4-7
2579841-3	1985	Beta TG plasma levels were inversely correlated with PaO2, directly with PaCO2 and [H+].	paco2	73-78	pro-platelet basic protein	Homo sapiens	0-7
6438124-6	1984	In control regions, CBF changed by 2.8-3.9% per mm Hg PaCO2 change, whereas in the spreading depression cortex, CBF changed by only 1.3-1.5%.	paco2	54-59	CCAAT/enhancer binding protein zeta	Rattus norvegicus	20-23
330831-7	1977	Further increase in CPAP did not result in any subsequent appreciable increase in Pes while PaO2 decreased slightly and PaCO2 increased.	paco2	120-125	centromere protein J	Homo sapiens	20-24
6799527-4	1981	The slope relating rCBF to PaCO2 averaged 1.5 ml 100 g-1 min-1 mm Hg-1 in 9 significantly affected regions.	paco2	27-32	CCAAT/enhancer binding protein zeta	Rattus norvegicus	19-23
6799527-5	1981	The findings suggest that rCBF declines during immobilization stress because of cerebrovascular constriction caused by a reduction in PaCO2.	paco2	134-139	CCAAT/enhancer binding protein zeta	Rattus norvegicus	26-30
6779497-8	1980	When PaCO2 was lowered to 30 Torr, under 70% nitrous oxide + 1% enflurane, there was a 43% decrease in CBF (from a mean of 42 ml/100 G/min.	paco2	5-10	CCAAT enhancer binding protein zeta	Homo sapiens	103-106
6420-4	1976	In anesthetized dogs with an increase in Paco2 of 30 mmHg for 4 h the plasma HCO3 increased 2 meq/1 and CSF 6 meq/1.	paco2	41-46	colony stimulating factor 1	Canis lupus familiaris	104-115
32531406-2	2020	We assessed the effect of PaCO2 on NSE in cerebrospinal fluid (CSF) and serum.	paco2	26-31	enolase 2	Homo sapiens	35-38
5714651-0	1968	Rate of reduction of CBF during voluntary step-wise reduction of PaCO2 in man.	paco2	65-70	CCAAT enhancer binding protein zeta	Homo sapiens	21-24
33404065-4	2021	The cerebrovascular responses to changes in arterial H+ /pH were altered in keeping with the altered relationship between PaCO2 and H+ /pH following NaHCO3 - infusion (i.e., changes in buffering capacity).	paco2	122-127	phenylalanine hydroxylase	Homo sapiens	57-59
33404065-4	2021	The cerebrovascular responses to changes in arterial H+ /pH were altered in keeping with the altered relationship between PaCO2 and H+ /pH following NaHCO3 - infusion (i.e., changes in buffering capacity).	paco2	122-127	phenylalanine hydroxylase	Homo sapiens	136-138
29992757-9	2018	Lower CC16 in gastric fluid was associated with higher FiO2 at 6 h (P = 0.009), higher PaCO2 at 24 h (P = 0.03), more ventilator days (P = 0.012) and more days with supplemental oxygen (P = 0.03).	paco2	87-92	secretoglobin family 1A member 1	Homo sapiens	6-10
31256309-8	2020	PaCO2 before intubation statistically increased compared with the baseline in groups P12 and P15, while decreased in group P20.	paco2	0-5	cyclin dependent kinase inhibitor 2B	Homo sapiens	93-96
32205957-60	2020	(UPP) Both critical care ventilators with leak compensation and bi-level ventilators have been equally effective in decreasing the WOB, RR, and PaCO2.	paco2	144-149	uridine phosphorylase 1	Homo sapiens	1-4
31256309-8	2020	PaCO2 before intubation statistically increased compared with the baseline in groups P12 and P15, while decreased in group P20.	paco2	0-5	DNA polymerase epsilon 4, accessory subunit	Homo sapiens	85-88
31297349-12	2019	Conclusion: Despite difficulties performing laparoscopic surgery in neonates, LEC was safe and feasible when intraperitoneal peak pressure was maintained under 10 mmHg and PaCO2 was closely monitored by a pediatric anesthesiologist.	paco2	172-177	C-C motif chemokine ligand 16	Homo sapiens	78-81
30660859-6	2019	Multiple regression analysis showed that PaCO2, as well as SaO2, was an independent variable for PAm.	paco2	41-46	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	97-100
29457280-8	2018	Besides, levels of PE750, PI885, PC792, PC826, PC830, PC854, PC802, and PG747 had an obvious negative correlation with levels of TNF-alpha, IL-10, IL-6, BUN, SCr, and PaCO2 , and a significant positive correlation with levels of HCO3- , PaO2 , and SaO2 .	paco2	167-172	tumor necrosis factor	Homo sapiens	129-138
29457280-8	2018	Besides, levels of PE750, PI885, PC792, PC826, PC830, PC854, PC802, and PG747 had an obvious negative correlation with levels of TNF-alpha, IL-10, IL-6, BUN, SCr, and PaCO2 , and a significant positive correlation with levels of HCO3- , PaO2 , and SaO2 .	paco2	167-172	interleukin 6	Homo sapiens	147-151
28148750-4	2017	If Cx26 were to be a universal and important CO2 sensor across all homeothermic animals, then a simple hypothesis would posit that it should exhibit evolutionary adaptation in animals with different homeostatic set points for the regulation of partial pressure of arterial CO2 (PaCO2).	paco2	278-283	gap junction protein beta 2	Homo sapiens	3-7
28636082-10	2018	Compared with the LPS group, the SA-B, SA-B + si-TRPM6, SA-B + si-TRPM7, si-TRPM6, and si-TRPM7 groups had increased PaO2 and the PaO2 /FiO2 , while decreased PaCO2, protein content, total WBC, PMN%, TNF-alpha, IL-6 levels, and lung coefficient.	paco2	159-164	SH3-domain binding protein 5	Rattus norvegicus	33-37
29791320-6	2018	SIGNIFICANCE: The ability to model the CBFV, ARI, HR, ABP, CrCP and RAP dependency of PaCO2 over its entire physiological range is a powerful tool for physiological and clinical studies, including the need to perform adjustments in disease populations with differing values of baseline PaCO2.	paco2	86-91	LDL receptor related protein associated protein 1	Homo sapiens	68-71
29791320-6	2018	SIGNIFICANCE: The ability to model the CBFV, ARI, HR, ABP, CrCP and RAP dependency of PaCO2 over its entire physiological range is a powerful tool for physiological and clinical studies, including the need to perform adjustments in disease populations with differing values of baseline PaCO2.	paco2	286-291	LDL receptor related protein associated protein 1	Homo sapiens	68-71
28291086-8	2017	The nociceptin/orphanin FQ peptide receptor antagonist J-113397 potentiated the respiratory depressant effects of cebranopadol; these changes in PaCO2 and PaO2 were fully reversible with the mu-opioid peptide receptor antagonist naloxone.	paco2	145-150	prepronociceptin	Rattus norvegicus	4-14
28291086-8	2017	The nociceptin/orphanin FQ peptide receptor antagonist J-113397 potentiated the respiratory depressant effects of cebranopadol; these changes in PaCO2 and PaO2 were fully reversible with the mu-opioid peptide receptor antagonist naloxone.	paco2	145-150	prepronociceptin	Rattus norvegicus	15-26
28148750-4	2017	If Cx26 were to be a universal and important CO2 sensor across all homeothermic animals, then a simple hypothesis would posit that it should exhibit evolutionary adaptation in animals with different homeostatic set points for the regulation of partial pressure of arterial CO2 (PaCO2).	paco2	278-283	complement C2	Homo sapiens	273-276
26628269-7	2017	Statistical analysis revealed good correlation between PaCO2 by IRMA and ABL (R2 = 0.766; p < 0.01) as well as between PTCCO2 and ABL (R2 = 0.619; p < 0.01), whereas correlation between PETCO2 and ABL was weaker (R2 = 0.405; p < 0.01).	paco2	55-60	ABL proto-oncogene 1, non-receptor tyrosine kinase	Homo sapiens	73-76