PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 8596745-6 1995 The significant positive correlations have been found between PPK and HbA1c in diabetic patients and between PPK and serum fructosamine concentration but only in diabetics without retinopathy. Fructosamine 123-135 kallikrein B1 Homo sapiens 109-112 7555472-12 1995 Fructosamine fell from a mean of 458 to 365 mumol/l at 3 months (P < 0.0001) and to 371 mumol/l at 6 months (P < 0.0001) and from 484 to 325 mumol/l at 3 months (P < 0.0001) and to 350 mumol/l at 6 months (P < 0.0001) for the combination and insulin groups, respectively. Fructosamine 0-12 insulin Homo sapiens 254-261 7740029-2 1994 Fructosamine concentrations were for the first time measured in children whose parents suffered from insulin-dependent or noninsulin-dependent diabetes mellitus. Fructosamine 0-12 insulin Homo sapiens 101-108 7659875-11 1994 Multivariate analysis showed that in the diabetic children the worsening of metabolic control as reflected by fructosamine, was positively correlated with the increase in total Lp(a) serum concentration. Fructosamine 110-122 lipoprotein(a) Homo sapiens 177-182 7979500-6 1994 Over the whole study period, children with mean insulin-breakfast intervals of two to 12 minutes had a mean fructosamine concentration of 376 mumol/l compared with 341 mumol/l in those with intervals of 15-35 minutes. Fructosamine 108-120 insulin Homo sapiens 48-55 8084293-7 1994 Triglyceride and apolipoprotein (apo) B levels and indexes of metabolic control or protein glycation (fasting blood glucose and fructosamine) also appeared to influence markedly both the kinetics of rouleau formation and the cohesion of the rouleau networks. Fructosamine 128-140 apolipoprotein B Homo sapiens 17-39 7835207-4 1994 There was a significant association between serum fructosamine levels and the total B12 binding capacity in poorly controlled diabetic patients and the decrease of fructosamine was correlated significantly with the change of total B12 binding capacity and serum B12 levels in diabetic patients. Fructosamine 164-176 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 231-234 8458194-4 1993 From Deming regression models, 95% prediction intervals for mean blood glucose for fructosamine and HbA1 values were calculated, showing that fructosamine predicted levels of mean blood glucose more precisely than HbA1. Fructosamine 142-154 hemoglobin subunit alpha 1 Homo sapiens 100-104 7835207-4 1994 There was a significant association between serum fructosamine levels and the total B12 binding capacity in poorly controlled diabetic patients and the decrease of fructosamine was correlated significantly with the change of total B12 binding capacity and serum B12 levels in diabetic patients. Fructosamine 50-62 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 84-87 7835207-4 1994 There was a significant association between serum fructosamine levels and the total B12 binding capacity in poorly controlled diabetic patients and the decrease of fructosamine was correlated significantly with the change of total B12 binding capacity and serum B12 levels in diabetic patients. Fructosamine 164-176 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 231-234 7931813-6 1994 The mean values of fructosamine measured by the NBT reaction in the glycosylated-laminin and fibronectin were increased dose dependently. Fructosamine 19-31 fibronectin 1 Rattus norvegicus 93-104 8227979-5 1993 The osteocalcin levels were negatively correlated both with fructosamine and with glycosylated hemoglobin (p < 0.01 and p < 0.001, respectively), and positively correlated with the degree of metabolic acidosis at onset (p < 0.05). Fructosamine 60-72 bone gamma-carboxyglutamate protein Homo sapiens 4-15 8482426-10 1993 A long-term trial of IGF-I (up to 16 mo) showed that IGF-I (0.1-0.4 mg/kg body wt twice daily) is effective in lowering both fasting and postprandial plasma glucose concentrations with decreases in both fructosamine and HbA1c values. Fructosamine 203-215 insulin like growth factor 1 Homo sapiens 53-58 8331612-6 1993 In diabetic dogs that were receiving insulin therapy, the fructosamine test reflected the glycemic state far more accurately than did individual blood glucose measurements. Fructosamine 58-70 insulin Canis lupus familiaris 37-44 8252716-4 1993 This inhibition was reduced by addition of nonionic detergents, which contain organic peroxide inhibitors of SOD, to the fructosamine reagent. Fructosamine 121-133 superoxide dismutase 1 Homo sapiens 109-112 1511806-9 1992 After diet therapy the increase in insulin sensitivity correlated with reductions in fasting plasma glucose levels (r = 0.97, p less than 0.001), reductions in serum fructosamine (r = 0.77, p less than 0.05), and weight loss (r = 0.78, p less than 0.05). Fructosamine 166-178 insulin Homo sapiens 35-42 8055819-3 1993 The mean values of concentration decrement after the first, second and third week of treatment were 0.47, 0.37 and 0.26 mmol/l, respectively, (median values 0.56, 0.33 and 0.17 mmol/l) for fructosamine concentration, and 1.8, 2.9 and 1.0% (median 1.5, 2.3 and 0.8%) for HbA1. Fructosamine 189-201 hemoglobin subunit alpha 1 Homo sapiens 270-274 1483456-10 1992 Oxygen, redox-active metal ions, catalase, superoxide dismutase and the pharmacological agent aminoguanidine are expected to be influential on the rate and fate of fructosamine degradation. Fructosamine 164-176 catalase Homo sapiens 33-41 1399128-6 1992 The same was found for the ratios C-peptide to glucose or C-peptide to fructosamine, indicating insulin resistance. Fructosamine 71-83 insulin Homo sapiens 96-103 1914798-8 1991 HbA1c correlated with fructosamine (r = 0.59) and Glyc PP-HPLC (r = 0.47) but correlated best with Glyc PP (r = 0.83). Fructosamine 22-34 hemoglobin subunit alpha 1 Homo sapiens 0-4 1773712-0 1991 Correction of fructosamine value for serum albumin and globulin concentrations. Fructosamine 14-26 albumin Homo sapiens 37-50 1773712-1 1991 Using the data of 131 patients with non-insulin dependent diabetes mellitus (NIDDM), the correction formulas of fructosamine value ([FRA]) were devised to standardize the uncorrected [FRA] to serum albumin concentrations ([ALB]) of 4 g/dl, globulin concentrations ([GLB]) of 3 g/dl, and total protein concentrations ([TP]) of 7 g/dl. Fructosamine 112-124 albumin Homo sapiens 192-205 1541051-4 1992 The in vivo TNF productivity in the diabetic rats, including the short-term- and long-term-diabetic rats, was correlated positively with the level of fructosamine/albumin (P less than 0.05) and negatively with the level of serum albumin (P less than 0.05), but not with levels of blood glucose. Fructosamine 150-162 tumor necrosis factor Rattus norvegicus 12-15 1345533-5 1992 When fructosamine concentration was considered as an index of metabolic control of diabetes, it was found that the levels of cholesterol, phospholipids and apolipoproteins apo-A and apo-AI are highest in the group with the poor metabolic control and differ significantly from the respective values found in patients with mediocre and good metabolic control. Fructosamine 5-17 apolipoprotein A1 Homo sapiens 172-177 1345533-5 1992 When fructosamine concentration was considered as an index of metabolic control of diabetes, it was found that the levels of cholesterol, phospholipids and apolipoproteins apo-A and apo-AI are highest in the group with the poor metabolic control and differ significantly from the respective values found in patients with mediocre and good metabolic control. Fructosamine 5-17 apolipoprotein A1 Homo sapiens 182-188 1819455-2 1991 Only the IgA myeloma group showed significantly raised serum fructosamine values (P less than 0.001). Fructosamine 61-73 CD79a molecule Homo sapiens 9-12 1819455-4 1991 The study shows that elevated IgA levels do influence serum fructosamine and this effect should be taken into due consideration in order to avoid possible misinterpretations in evaluating this widely used index of glucose metabolism. Fructosamine 60-72 CD79a molecule Homo sapiens 30-33 1942633-9 1991 In aged subjects with poor ADL, HbA1, HbA1c and plasma glucose should be determined with fructosamine. Fructosamine 89-101 hemoglobin subunit alpha 1 Homo sapiens 32-36 1934502-5 1991 Longitudinal analysis of individual patients" data over the 16-wk period showed a significant correlation between serum fructosamine and HbA1 (r = 0.55 to r = 0.94) which was present in 8 out of 14 patients. Fructosamine 120-132 hemoglobin subunit alpha 1 Homo sapiens 137-141 1934502-6 1991 The changes in fructosamine concentration preceded those observed in HbA1. Fructosamine 15-27 hemoglobin subunit alpha 1 Homo sapiens 69-73 1934502-7 1991 The ratio of fructosamine/HbA1 predicted the changes in HbA1 over the following month (r = 0.54, P less than 0.001). Fructosamine 13-25 hemoglobin subunit alpha 1 Homo sapiens 56-60 1934502-8 1991 Thus, we demonstrated that the parallel measurement of fructosamine and HbA1 provides information on future trends in HbA1 concentration in diabetic patients. Fructosamine 55-67 hemoglobin subunit alpha 1 Homo sapiens 118-122 2351039-9 1990 Fructosamine correlated less well with both HbA1 (r = 0.55) and glucose (r = 0.51). Fructosamine 0-12 hemoglobin subunit alpha 1 Homo sapiens 44-48 2208664-5 1990 In diabetic patients the average concentration of fructosamine in serum exceeded that in nondiabetic subjects and correlated with the preprandial serum glucose and with other measures of deteriorating glycemic control (e.g., increased need for insulin therapy). Fructosamine 50-62 insulin Homo sapiens 244-251 2175697-6 1990 Plasma thrombomodulin concentrations were positively correlated with the level of serum creatine, blood urea nitrogen, urinary albumin and urinary beta 2-microglobulin (P less than 0.001 for each), but not with fasting plasma glucose, hemoglobin A1c or fructosamine. Fructosamine 253-265 thrombomodulin Homo sapiens 7-21 2237829-2 1990 Twenty two patients with established diabetes mellitus have been studied and qualitative abnormalities of vWf:Ag multimers were found in 10 patients who had poorer glycaemic control (as judged by plasma fructosamine) than the other 12 patients. Fructosamine 203-215 von Willebrand factor Homo sapiens 106-109 2378195-3 1990 Fructosamine concentrations correlated significantly with fasting blood glucose and HbA1 in diabetics (r = 0.677, p less than 0.0005, and r = 0.598, p less than 0.0005, respectively). Fructosamine 0-12 hemoglobin subunit alpha 1 Homo sapiens 84-88 2378195-4 1990 The correlation between fructosamine and HbA1 was significant in the oral hypoglycemic-treated diabetics and poor in the insulin-treated diabetic group (r = 0.568, p less than 0.0005, and r = 0.526, p = 0.01). Fructosamine 24-36 hemoglobin subunit alpha 1 Homo sapiens 41-45 2378195-4 1990 The correlation between fructosamine and HbA1 was significant in the oral hypoglycemic-treated diabetics and poor in the insulin-treated diabetic group (r = 0.568, p less than 0.0005, and r = 0.526, p = 0.01). Fructosamine 24-36 insulin Homo sapiens 121-128 2137219-9 1990 Thus, TG, TC, LDL-C and ApoB are increased in young diabetics whose HbA1 and fructosamine levels exceed reference values by more than 5 standard deviations. Fructosamine 77-89 apolipoprotein B Homo sapiens 24-28 2335179-6 1990 Serum fructosamine levels were closely correlated to the HbA1 levels. Fructosamine 6-18 hemoglobin subunit alpha 1 Homo sapiens 57-61 34753797-0 2022 An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript. Fructosamine 45-57 reticulocalbin 3 Homo sapiens 76-80 2321399-8 1990 An influence of fibrinogen on fructosamine is also conceivable. Fructosamine 30-42 fibrinogen beta chain Homo sapiens 16-26 34314247-0 2021 A hypothesis: Fructosamine-3-Kinase-Related-Protein (FN3KRP) catalyzes deglycation of Maillard intermediates directly downstream from fructosamines. Fructosamine 134-147 fructosamine 3 kinase related protein Homo sapiens 14-51 34314247-0 2021 A hypothesis: Fructosamine-3-Kinase-Related-Protein (FN3KRP) catalyzes deglycation of Maillard intermediates directly downstream from fructosamines. Fructosamine 134-147 fructosamine 3 kinase related protein Homo sapiens 53-59 34135606-9 2021 In diabetic patients, the concentrations of glycated Tf in serum were significantly correlated with those of fructosamine.Tf has a shorter half-life, and not affected by anemia or hypoalbuminemia and less negative charge under physiological conditions, while glycated modification could not change the isoelectric point of Tf, which easily passes through the negatively charged basement membrane of the glomerulus. Fructosamine 109-121 transferrin Homo sapiens 122-124 2242825-7 1990 For PAI, we found only weak nonsignificant positive correlations to D-dimer and fructosamine and weak but highly significant correlations to HbA1c. Fructosamine 80-92 serpin family E member 1 Homo sapiens 4-7 2242825-8 1990 These results are indicative for an increase of PAI with diminished glycometabolic control as measured with the HbA1c and fructosamine level. Fructosamine 122-134 serpin family E member 1 Homo sapiens 48-51 34494136-16 2021 Increased valvular expression of NF-kappaB in diabetic individuals is associated not only with serum HbA1c and fructosamine levels but also with AVA and transvalvular gradient, indicating that strict long-term glycaemic control is needed in AS patients with concomitant type 2 diabetes. Fructosamine 111-123 nuclear factor kappa B subunit 1 Homo sapiens 33-42 34753797-0 2022 An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript. Fructosamine 45-57 Fc gamma receptor and transporter Homo sapiens 119-124 2625004-0 1989 Binding of nitroblue tetrazolium to human serum albumin in a fructosamine test. Fructosamine 61-73 albumin Homo sapiens 42-55 2692874-2 1989 Serum fructosamine correlated less closely with HbA1 (r = 0.44) than did HbA1 with glycated serum albumin (GSA) (r = 0.68). Fructosamine 6-18 hemoglobin subunit alpha 1 Homo sapiens 48-52 2731364-0 1989 Correlation of HbA1C, glycated serum proteins and albumin, and fructosamine with the 24-h glucose profile of insulin-dependent pregnant diabetics. Fructosamine 63-75 insulin Homo sapiens 109-116 2532106-6 1989 Glycosylated serum albumin correlated with HbA1 and fructosamine levels throughout the year (rs 0.47-0.68 and 0.48-0.76, respectively), but HbA1 and fructosamine were less clearly correlated with each other (rs 0.38-0.44), with no significant association immediately after the period of intensive management or 3 months later. Fructosamine 52-64 albumin Homo sapiens 19-26 2776348-5 1989 There was a correlation between fructosamine concentration and serum albumin. Fructosamine 32-44 albumin Homo sapiens 69-76 2776348-9 1989 Albumin is the major factor affecting serum fructosamine concentrations. Fructosamine 44-56 albumin Homo sapiens 0-7 2739139-2 1989 Therefore, we investigated the relationship between serum fructosamine levels and serum total protein and albumin levels measured simultaneously in non-diabetic and diabetic patients. Fructosamine 58-70 albumin Homo sapiens 106-113 2910553-4 1989 In a group of nondiabetic patients with pathological values for IgA concentrations, 79.4% had pathological values for fructosamine. Fructosamine 118-130 immunoglobulin heavy variable 4-38-2-like Homo sapiens 64-67 2722131-5 1989 During the second trimester a significantly lower fructosamine level (1.92 +/- 0.21 mmol/l) has been found in pregnant women, most likely due to the low serum albumin concentration (31.35 +/- 3.97 g/l). Fructosamine 50-62 albumin Homo sapiens 153-166 3254102-4 1988 Fructosamine correlated with HbA1 both in IDDM (n = 110, r = 0.701, P less than 0.001) and NIDDM (n = 71, r = 0.764, P less than 0.001). Fructosamine 0-12 hemoglobin subunit alpha 1 Homo sapiens 29-33 3254102-5 1988 Specificity and sensitivity of fructosamine for the prediction of degree of control assessed on the basis of HbA1 level (cut-off point for good vs. poor control, HbA1 = 10%) was determined. Fructosamine 31-43 hemoglobin subunit alpha 1 Homo sapiens 109-113 3254102-5 1988 Specificity and sensitivity of fructosamine for the prediction of degree of control assessed on the basis of HbA1 level (cut-off point for good vs. poor control, HbA1 = 10%) was determined. Fructosamine 31-43 hemoglobin subunit alpha 1 Homo sapiens 162-166 3365012-4 1988 There was a highly significant correlation between HbA1c and fructosamine in the diabetic children but this was lost when only concentrations within the established normal ranges were considered. Fructosamine 61-73 hemoglobin subunit alpha 1 Homo sapiens 51-55 3214127-0 1988 Serum fructosamine does reflect levels of glycated serum albumin in insulin-dependent diabetics. Fructosamine 6-18 albumin Homo sapiens 57-64 3214127-3 1988 We conclude, that fructosamine measurements accurately reflect GSA concentrations, and, therefore, provide a practical method for assessing intermediate term glycaemia in IDD. Fructosamine 18-30 GNAS complex locus Homo sapiens 63-66 3391095-4 1988 Fructosamine correlated moderately well with HbA1 (affinity; r = .8) and placed 71% of IDDM and 72% of NIDDM patients in the same clinical category of good, moderate, or poor control. Fructosamine 0-12 hemoglobin subunit alpha 1 Homo sapiens 45-49 3802464-2 1987 We report the marked inhibitory effect of superoxide dismutase (EC 1.15.1.1) on the reducing activity both of protein glycated in vitro and of diabetic sera, indicating superoxide intermediacy in the fructosamine reaction. Fructosamine 200-212 Susceptibility to lysis by alloreactive natural killer cells Homo sapiens 64-68 2838494-4 1988 A test for fructosamine quantification is based on nitroblue tetrazolium (NBT) reduction, in which O2- is involved, the reduction being inhibited in the presence of superoxide dismutase (SOD). Fructosamine 11-23 superoxide dismutase 1 Homo sapiens 165-185 2838494-4 1988 A test for fructosamine quantification is based on nitroblue tetrazolium (NBT) reduction, in which O2- is involved, the reduction being inhibited in the presence of superoxide dismutase (SOD). Fructosamine 11-23 superoxide dismutase 1 Homo sapiens 187-190 3600671-6 1987 In the diabetic patients we found a significant correlation between serum fructosamine and HbA1 values (r = 0.87, p less than 0.001). Fructosamine 74-86 hemoglobin subunit alpha 1 Homo sapiens 91-95 3827184-3 1987 Glycated haemoglobin (HbA1) correlated with glycated albumin and fructosamine in the diabetic group. Fructosamine 65-77 hemoglobin subunit alpha 1 Homo sapiens 22-26 3436113-2 1987 A significant correlation between fructosamine and HbA1 values (r = 0.70, p less than 0.001) was evidenced in Group A. Fructosamine 34-46 hemoglobin subunit alpha 1 Homo sapiens 51-55 3555181-0 1987 [Serum fructosamine in the monitoring of insulin therapy in the diabetic child]. Fructosamine 7-19 insulin Homo sapiens 41-48 6426612-0 1984 Serum fructosamine concentrations in patients with type II (non-insulin-dependent) diabetes mellitus during changes in management. Fructosamine 6-18 insulin Homo sapiens 64-71 4028402-5 1985 Fructosamine accurately reflected blood glucose control as evidenced by the significant correlation with glucose concentrations in fasting plasma (r = 0.82, p less than 0.001) and with glycated hemoglobin (HbA1c) (r = 0.87, p less than 0.01) in 115 patients with type 2 (non-insulin-dependent) diabetes mellitus. Fructosamine 0-12 insulin Homo sapiens 275-282 3954436-3 1986 Fructosamine correlated with HbA1 and with average glucose values measured over 30 days. Fructosamine 0-12 hemoglobin subunit alpha 1 Homo sapiens 29-33 4025000-0 1985 [N-acetyl-beta-D-glucosaminidase activity in relation to blood glucose, serum fructosamine and type I diabetic nephropathy]. Fructosamine 78-90 O-GlcNAcase Homo sapiens 1-32 33707127-5 2021 A similar fructosamine derivative of serum albumin, glycated albumin (GA), finds use as a biomarker of glycemic control, particularly where there is interference in use of A1C. Fructosamine 10-22 albumin Homo sapiens 43-50 33426749-10 2021 There were negative correlations between SPX and serum concentration of insulin (P < .05); leptin (P < .01), triglycerides (P < .01), total cholesterol (P < .01), nonesterified fatty acids (P < .01), and fructosamine (P < .01). Fructosamine 204-216 spexin hormone Canis lupus familiaris 41-44 31830262-10 2019 ROCK1 and TGM2 expressions in TMAs were correlated with passive lumen diameter, plasma glucose, fructosamine, and total cholesterol. Fructosamine 96-108 Rho associated coiled-coil containing protein kinase 1 Homo sapiens 0-5 32273829-8 2020 The group presenting higher expression of ALOX5 and of LTB4R also presented higher values of HbA1C, of fructosamine, and of plasmatic LTB4. Fructosamine 103-115 arachidonate 5-lipoxygenase Homo sapiens 42-47 32273829-8 2020 The group presenting higher expression of ALOX5 and of LTB4R also presented higher values of HbA1C, of fructosamine, and of plasmatic LTB4. Fructosamine 103-115 leukotriene B4 receptor Homo sapiens 55-60 33424218-2 2020 In patients with T2DM and ESRD, insulin is the antidiabetic medication of choice with a hemoglobin A1c target of 6 to 8%, using fructosamine levels or other measures for better assessment of glycemic control. Fructosamine 128-140 insulin Homo sapiens 32-39 32315583-7 2020 Furthermore, fructosamine was more strongly correlated with fasting glucose than albumin-corrected fructosamine (r =0.43, p = 0.002 vs r = 0.32, p = 0.026). Fructosamine 99-111 albumin Felis catus 81-88 31830262-10 2019 ROCK1 and TGM2 expressions in TMAs were correlated with passive lumen diameter, plasma glucose, fructosamine, and total cholesterol. Fructosamine 96-108 transglutaminase 2 Homo sapiens 10-14 29890544-6 2019 Surprisingly, OGA activity was not correlated hyperglycaemia markers (blood glucose, fructosamine, HbA1c) but was positively correlated with the inflammatory marker C-reactive protein. Fructosamine 85-97 O-GlcNAcase Homo sapiens 14-17 30520545-5 2019 Neprilysin inhibition translated into an increase in its substrates such as atrial natriuretic peptide (ANP), substance P, and glucagon-like peptide 1, the latter translating into a decrease in fructosamine. Fructosamine 194-206 membrane metalloendopeptidase Homo sapiens 0-10 31219796-7 2019 The objective of this study was to measure the urinary netrin-1 level, a marker of tubular injury in children with normoalbuminuric (NA) T1D, and to determine its relationship with short-term fluctuations in blood glucose using fructosamine levels. Fructosamine 228-240 netrin 1 Homo sapiens 55-63 31219796-9 2019 The relationship of the netrin-1 levels with diabetes parameters such as fructosamine, hemoglobin A1c (HbA1c) or duration of diabetes was investigated. Fructosamine 73-85 netrin 1 Homo sapiens 24-32 31219796-11 2019 Urinary netrin-1 was found to correlate with HbA1c (p = 0.007, r = 0.320) and fructosamine (p = 0.04, r = 0.310) but not with average HbA1c in the last year (p = 0.14, r = -0.19), duration of diabetes (p = 0.83, r = 0.02) or other diabetes indices. Fructosamine 78-90 netrin 1 Homo sapiens 8-16 30922869-8 2019 The expression of miR-20a-5p in PBMCs was correlated with fructosamine concentration (r = 0.62, p = 0.006). Fructosamine 58-70 membrane associated ring-CH-type finger 8 Homo sapiens 18-21 28145031-8 2017 Product of fructosamine concentration and insulin dose was calculated as an indicator of insulin resistance (Insulin Resistance Index). Fructosamine 11-23 insulin Felis catus 89-96 30112786-11 2018 Insulin-like growth factor-I was positively associated with TC (P < .0001) and endogenous insulin (P = .005) and negatively associated with fructosamine (P < .0001). Fructosamine 143-155 insulin Felis catus 0-7 29844224-4 2018 Among whites, rs34459162, a novel missense single nucleotide polymorphism (SNP) in RCN3, was associated with fructosamine (P = 5.3 x 10-9) and rs1260236, a known diabetes-related missense mutation in GCKR, was associated with percent glycated albumin (P = 5.9 x 10-9) and replicated in CARDIA. Fructosamine 109-121 reticulocalbin 3 Homo sapiens 83-87 29436378-7 2018 Equivalent concentrations of fructosamine and glycated albumin corresponding to an HbA1c of 6.5% (96.5 percentile) were 270.2 mumol/L and 15.6%, respectively. Fructosamine 29-41 hemoglobin subunit alpha 1 Homo sapiens 83-87 30042059-5 2018 In addition, alpha-Klotho and beta-Klotho levels were negatively correlated with serum fructosamine and HbA1c but were not associated with serum glucose in the model including all participants. Fructosamine 87-99 klotho Homo sapiens 19-25 30042059-5 2018 In addition, alpha-Klotho and beta-Klotho levels were negatively correlated with serum fructosamine and HbA1c but were not associated with serum glucose in the model including all participants. Fructosamine 87-99 klotho beta Homo sapiens 30-41 28145031-8 2017 Product of fructosamine concentration and insulin dose was calculated as an indicator of insulin resistance (Insulin Resistance Index). Fructosamine 11-23 insulin Felis catus 109-116 27394048-4 2017 The dialyzed solution (containing +-1000 micromol/L fructosamine) was used as an FN3K substrate. Fructosamine 52-64 fructosamine 3 kinase Homo sapiens 81-85 27777100-6 2017 With diabetes defined by HbA1C >=6.5% (48mmol/mol), the areas under the ROCs of FAAlb (0.905) and FATP (0.895) were both significantly greater (P<0.001) than that of uncorrected fructosamine (0.878). Fructosamine 184-196 solute carrier family 27 member 1 Homo sapiens 101-105 27394048-7 2017 The decrease in fructosamine concentration over time is a measure for the FN3K activity (1 U corresponding to 1 micromol/min). Fructosamine 16-28 fructosamine 3 kinase Homo sapiens 74-78 27172719-5 2016 RESULTS: Fructosamine level and HOMA index were the most important characteristics responsible for MCD in patients with CPD and DM2. Fructosamine 9-21 immunoglobulin heavy diversity 1-14 (non-functional) Homo sapiens 128-131 27271183-8 2016 Improved insulin sensitivity was sufficient to significantly lower glycated albumin (-1.7%, P = 0.034) and fructosamine (-38.7 mumol/L, P = 0.045) at the end of dosing and HbA1c (-0.44% [-4.9 mmol/mol], P = 0.025) 3 months postdosing. Fructosamine 107-119 insulin Homo sapiens 9-16 29318157-8 2017 MBL levels decreased by 10% from 2165 mug/L (IQR 919-3389 mug/L) at baseline to 1928 mu/L (IQR 811-2758 mug/L) at follow-up (P = 0.005), but MBL change was not significantly correlated with changes in insulin dose, HbA1c, or fructosamine. Fructosamine 225-237 mannose binding lectin 2 Homo sapiens 0-3 27751668-7 2016 Hazard ratios for the lowest decile of fructosamine were estimated by Cox regression for all-cause (n = 41,388 deaths) and cause-specific mortality during 25 years of follow-up. Fructosamine 39-51 cytochrome c oxidase subunit 8A Homo sapiens 70-73 26850632-7 2016 An in vitro removal of fructosamine of the valve was initiated using ATP-dependent fructosamine 3-kinase (FN3K). Fructosamine 23-35 fructosamine 3 kinase Homo sapiens 83-104 26850632-7 2016 An in vitro removal of fructosamine of the valve was initiated using ATP-dependent fructosamine 3-kinase (FN3K). Fructosamine 23-35 fructosamine 3 kinase Homo sapiens 106-110 26850632-11 2016 In the in vitro deglycation study, a significant lower aortic valve fructosamine concentration was detected after treatment with FN3K. Fructosamine 68-80 fructosamine 3 kinase Homo sapiens 129-133 27172719-6 2016 CONCLUSION: The data obtained demonstrate the significance of fructosamine level and HOMA index in the development of MCD in patients with CPD and DM2. Fructosamine 62-74 immunoglobulin heavy diversity 1-14 (non-functional) Homo sapiens 147-150 26147990-0 2015 Oxidized LDL and Fructosamine Associated with Severity of Coronary Artery Atherosclerosis in Insulin Resistant Pigs Fed a High Fat/High NaCl Diet. Fructosamine 17-29 insulin Sus scrofa 93-100 26352355-5 2015 FN3K phosphorylates fructosamines on the third carbon of their sugar moiety, making them unstable and causing them to detach from proteins, suggesting a protective role of this enzyme. Fructosamine 20-33 fructosamine 3 kinase Homo sapiens 0-4 26086231-6 2015 RESULTS: Insulin detemir administration resulted in a significant decrease in blood glucose and serum fructosamine concentrations at 6 months, compared with pretreatment values. Fructosamine 102-114 insulin Canis lupus familiaris 9-16 27509724-2 2014 We describe a non-diabetic patient with IgA type M-protein whose serum fructosamine and glycoalbumin levels were elevated. Fructosamine 71-83 myomesin 2 Homo sapiens 49-58 24939145-7 2014 MMF administration decreased the gene expression of TNF-alpha and TGF-beta1 in kidney tissues, serum glucose, fructosamine, urea, creatinine, C-reactive protein, malondialdehyde, urinary microalbumin and total protein. Fructosamine 110-122 tumor necrosis factor Rattus norvegicus 52-61 26015742-3 2015 This study was done to measure the level of serum fructosamine and Glycated hemoglobin (HbA1c) in Gestational Diabetes mellitus (GDM) patients and to compare with pregnant women without diabetes and healthy non-pregnant adults, to determine the pattern of change in serum fructosamine, influence of serum fructosamine and HbA1c values and to evaluate the efficacy of patient"s treatment. Fructosamine 272-284 hemoglobin subunit alpha 1 Homo sapiens 88-92 26015742-3 2015 This study was done to measure the level of serum fructosamine and Glycated hemoglobin (HbA1c) in Gestational Diabetes mellitus (GDM) patients and to compare with pregnant women without diabetes and healthy non-pregnant adults, to determine the pattern of change in serum fructosamine, influence of serum fructosamine and HbA1c values and to evaluate the efficacy of patient"s treatment. Fructosamine 272-284 hemoglobin subunit alpha 1 Homo sapiens 88-92 26015742-4 2015 In this study the level of fructosamine was positively correlated to HbA1c during 2(nd) trimesters of gestational period, implying that the level of fructosamine can be used to screen Gestational diabetes mellitus. Fructosamine 27-39 hemoglobin subunit alpha 1 Homo sapiens 69-73 26015742-4 2015 In this study the level of fructosamine was positively correlated to HbA1c during 2(nd) trimesters of gestational period, implying that the level of fructosamine can be used to screen Gestational diabetes mellitus. Fructosamine 149-161 hemoglobin subunit alpha 1 Homo sapiens 69-73 25450815-8 2015 More insulin-resistant patients had a greater sub scapular fold thickness, a higher incidence of obesity (12% vs. 1.7% p 0.007), higher fructosamine levels (496 vs. 403 p<0.00019, and a higher incidence of altered lipid metabolism (70% vs. 39% p 0.0007). Fructosamine 136-148 insulin Homo sapiens 5-12 22762347-5 2012 Percentage absolute change in fructosamine (% Delta Fru ) was the primary endpoint. Fructosamine 30-42 zinc finger and BTB domain containing 22 Homo sapiens 52-55 23020608-9 2013 The risk for additional insulin was 4.6-fold in women with baseline serum fructosamine concentration above median compared with those below median. Fructosamine 74-86 insulin Homo sapiens 24-31 25340725-10 2014 The HI-vaspin group maintained a better glucose, insulin, HOMA, fructosamine, HDL-cholesterol, and triglyceride profile throughout. Fructosamine 64-76 serpin family A member 12 Homo sapiens 7-13 20967558-2 2012 Fructosamine-3-kinase (FN3K), an enzyme found in mammals and birds, phosphorylates fructosamines on the third carbon of their sugar moiety, making them unstable and causing them to detach from proteins. Fructosamine 83-96 fructosamine 3 kinase Homo sapiens 0-21 20967558-2 2012 Fructosamine-3-kinase (FN3K), an enzyme found in mammals and birds, phosphorylates fructosamines on the third carbon of their sugar moiety, making them unstable and causing them to detach from proteins. Fructosamine 83-96 fructosamine 3 kinase Homo sapiens 23-27 20967558-4 2012 Mice deficient in FN3K accumulate protein-bound fructosamines and free fructoselysine, indicating that the deglycation mechanism initiated by FN3K is operative in vivo. Fructosamine 48-61 fructosamine 3 kinase Mus musculus 18-22 19834870-3 2010 Fructosamine-3-kinase (FN3K) is an intracellular enzyme that phosphorylates fructosamines resulting in fructosamine-3-phosphate, which subsequently decomposes to inorganic phosphate, 3-deoxyglucasone and the unmodified amine. Fructosamine 76-89 fructosamine 3 kinase Homo sapiens 0-21 21270274-7 2011 Chronic treatment in db/db mice (50 mg/kg/bid; 45 days) reduced postabsorptive glycemia (-38%), water consumption (-31%), and fructosamine (-30%). Fructosamine 126-138 BH3 interacting domain death agonist Mus musculus 42-45 21441659-6 2011 alpha-Synuclein is glycated using methylglyoxal and formation of AGE-alpha-synuclein is characterized using fluorescence studies, intrinsic tyrosine fluorescence, and fructosamine estimation. Fructosamine 167-179 synuclein alpha Homo sapiens 0-15 21441659-6 2011 alpha-Synuclein is glycated using methylglyoxal and formation of AGE-alpha-synuclein is characterized using fluorescence studies, intrinsic tyrosine fluorescence, and fructosamine estimation. Fructosamine 167-179 synuclein alpha Homo sapiens 69-84 20416371-7 2010 Periodic acid-Schiff staining and fructosamine assay demonstrated that Trx-1 was rapidly glycated by LPS. Fructosamine 34-46 thioredoxin Homo sapiens 71-76 21288167-2 2011 Fructosamine 3-kinase (FN3K), initially identified in erythrocytes, appears to be responsible for the removal of fructosamine from proteins, suggesting a protective role in nonenzymatic glycation. Fructosamine 113-125 fructosamine 3 kinase Homo sapiens 0-21 21288167-2 2011 Fructosamine 3-kinase (FN3K), initially identified in erythrocytes, appears to be responsible for the removal of fructosamine from proteins, suggesting a protective role in nonenzymatic glycation. Fructosamine 113-125 fructosamine 3 kinase Homo sapiens 23-27 20722686-7 2010 Insulin sensitivity K(ITT) was associated with physical activity energy expenditure (P = 0.006), energy intake (P = 0.047) and the change in fructosamine level (P = 0.016) but not with changes in body weight, subcutaneous fat area, visceral fat area or adipokine level. Fructosamine 141-153 insulin Homo sapiens 0-7 19834870-3 2010 Fructosamine-3-kinase (FN3K) is an intracellular enzyme that phosphorylates fructosamines resulting in fructosamine-3-phosphate, which subsequently decomposes to inorganic phosphate, 3-deoxyglucasone and the unmodified amine. Fructosamine 76-89 fructosamine 3 kinase Homo sapiens 23-27 18802325-9 2009 The fibrillin-1 isolated from the youngest group had the highest capacity to form fructosamine and AGEs under glycation in vitro. Fructosamine 82-94 fibrillin 1 Homo sapiens 4-15 19566967-5 2009 Insulin sensitivity was evaluated via postprandial changes in serum glucose and insulin, oral glucose tolerance tests, and fasting serum insulin and fructosamine concentrations. Fructosamine 149-161 insulin Bos taurus 0-7 19484197-5 2009 HSA-AGE was prepared by incubating HSA with glucose, and assessed using the fructosamine assay, mass spectrometry, SDS-PAGE and fluorometry. Fructosamine 76-88 albumin Homo sapiens 0-3 18319580-2 2008 Diabetic dogs were treated with insulin injections, however their plasma glucose and fructosamine concentrations were significantly higher than those of the controls. Fructosamine 85-97 insulin Canis lupus familiaris 32-39 17681011-1 2007 The purpose of this work was to identify the function of bacterial homologues of fructosamine 3-kinase (FN3K), a mammalian enzyme responsible for the removal of fructosamines from proteins. Fructosamine 161-174 fructosamine 3 kinase Homo sapiens 81-102 19055108-4 2008 HbA1c (%) and fructosamine levels in the GP1 and GP2 diabetic subjects and the controls were 5.75 (0.67), 11.43 (2.01) and 4.33 (0.47), and 3.09 (0.57), 6.09 (1.15) and 1.67 (0.31), respectively (GP1 vs. GP2, GP1 vs. GC and GP2 vs. CG, all P < 0.001). Fructosamine 14-26 GTP binding protein 1 Homo sapiens 41-44 19055108-4 2008 HbA1c (%) and fructosamine levels in the GP1 and GP2 diabetic subjects and the controls were 5.75 (0.67), 11.43 (2.01) and 4.33 (0.47), and 3.09 (0.57), 6.09 (1.15) and 1.67 (0.31), respectively (GP1 vs. GP2, GP1 vs. GC and GP2 vs. CG, all P < 0.001). Fructosamine 14-26 glycoprotein 2 Homo sapiens 49-52 18720163-2 2008 Our aim is to evaluate, in diabetic and non diabetic subjects, the relationship of ApoB-G with serum fasting glucose, fructosamine, stable and labile fractions of glycated hemoglobin ((S)HbA(1c), (L)HbA(1c), respectively) and insulin. Fructosamine 118-130 apolipoprotein B Homo sapiens 83-87 17686456-1 2007 Fructosamine-3-kinase (FN3K) phosphorylates fructosamines to fructosamine-3-phosphates. Fructosamine 44-57 fructosamine 3 kinase Homo sapiens 0-21 17686456-1 2007 Fructosamine-3-kinase (FN3K) phosphorylates fructosamines to fructosamine-3-phosphates. Fructosamine 44-57 fructosamine 3 kinase Homo sapiens 23-27 17681011-1 2007 The purpose of this work was to identify the function of bacterial homologues of fructosamine 3-kinase (FN3K), a mammalian enzyme responsible for the removal of fructosamines from proteins. Fructosamine 161-174 fructosamine 3 kinase Homo sapiens 104-108 17322487-2 2007 We present two cases of patients with rheumatoid arthritis (RA) and concomitant diabetes mellitus, who showed a marked decrease of fructosamine levels after initiating therapy with adalimumab, a TNFalpha-blocking agent, for active RA. Fructosamine 131-143 tumor necrosis factor Homo sapiens 195-203 17969818-10 2007 The level of GSH and catalase activity, however, were significantly reduced in the patients on conventional therapy due to the increased susceptibility to H2O2-induced oxidative stress CONCLUSION: The presented study confirmed positive effect of intensive insulin therapy on metabolic control expressed through glycemia level glycolysed hemoglobine (HbAlc) and fructosamine, as well as through antioxidative/prooxidative homeostasis. Fructosamine 361-373 insulin Homo sapiens 256-263 16920277-3 2007 Because of these considerations, we have proposed that the intrinsic toxicity of glucose and other sugars is counteracted in vivo by active deglycation mechanisms including transglycation of Schiff"s bases and FN3K-dependent breakdown of fructosamines. Fructosamine 238-251 fructosamine 3 kinase Homo sapiens 210-214 17068132-5 2007 When administered daily for 6 wk to diabetic rhesus monkeys, FGF-21 caused a dramatic decline in fasting plasma glucose, fructosamine, triglycerides, insulin, and glucagon. Fructosamine 121-133 fibroblast growth factor 21 Macaca mulatta 61-67 16634114-6 2007 Concerning differences between LDL subfractions isolated from DM2 and from control subjects, the former showed increased MDA, fructosamine and gLDL proportion and decreased LDL size and antioxidant content. Fructosamine 126-138 immunoglobulin heavy diversity 1-14 (non-functional) Homo sapiens 62-65 16634114-7 2007 The only effect of glycemic optimization was a decrease in fructosamine and gLDL in LDL(+) from DM2 subjects. Fructosamine 59-71 immunoglobulin heavy diversity 1-14 (non-functional) Homo sapiens 96-99 18334852-2 2007 Instead, recent identification of fructosamine 3 kinase (FN3K) has unveiled that fructosamines can be physiologically repaired, so that the FN3K enzyme could be considered a new form of protein repair. Fructosamine 81-94 fructosamine 3 kinase Homo sapiens 34-55 18334852-2 2007 Instead, recent identification of fructosamine 3 kinase (FN3K) has unveiled that fructosamines can be physiologically repaired, so that the FN3K enzyme could be considered a new form of protein repair. Fructosamine 81-94 fructosamine 3 kinase Homo sapiens 57-61 18334852-2 2007 Instead, recent identification of fructosamine 3 kinase (FN3K) has unveiled that fructosamines can be physiologically repaired, so that the FN3K enzyme could be considered a new form of protein repair. Fructosamine 81-94 fructosamine 3 kinase Homo sapiens 140-144 17072594-1 2006 Fructosamine-3-kinase (FN3K) mediates the regeneration of lysine from fructosamines formed on proteins as a result of the "early" Maillard reaction. Fructosamine 70-83 fructosamine 3 kinase Homo sapiens 0-21 17072594-1 2006 Fructosamine-3-kinase (FN3K) mediates the regeneration of lysine from fructosamines formed on proteins as a result of the "early" Maillard reaction. Fructosamine 70-83 fructosamine 3 kinase Homo sapiens 23-27 17072594-2 2006 As fructosamines and advanced glycation endproducts derived therefrom are supposed to play an adverse role in the development of diabetic complications, FN3K is discussed as a protein-repairing enzyme. Fructosamine 3-16 fructosamine 3 kinase Homo sapiens 153-157 17072594-4 2006 The assay is based on the FN3K-dependent conversion of the synthetic UV-active fructosamine Nalpha-hippuryl-Nepsilon-(1-deoxy-D-fructosyl)lysine (BzGFruK) to Nalpha-hippuryl-Nepsilon-(phosphofructosyl)lysine (BzGpFruK). Fructosamine 79-91 fructosamine 3 kinase Homo sapiens 26-30 16513102-3 2006 METHODS: We adapted the nitroblue tetrazolium assay to measure in micro-well plates the fructosamine content of transferrin isolated from serum by immunocomplexation. Fructosamine 88-100 transferrin Homo sapiens 112-123 16819943-3 2006 Fn3k-/- mice looked healthy and had normal blood glucose and serum fructosamine levels. Fructosamine 67-79 fructosamine 3 kinase Mus musculus 0-4 16819943-6 2006 Other intracellular proteins were also significantly more glycated in Fn3k-/- mice in erythrocytes (1.8-2.2-fold) and in brain, kidney, liver and skeletal muscle (1.2-1.8-fold), indicating that FN3K removes fructosamines from intracellular proteins in vivo. Fructosamine 207-220 fructosamine 3 kinase Mus musculus 70-74 16275041-5 2006 Insulin doses were adjusted as needed to resolve clinical signs and lower serum fructosamine concentrations. Fructosamine 80-92 insulin Felis catus 0-7 16670083-1 2006 Fructosamine-3-kinase (FN3K) is a recently described protein-repair enzyme responsible for the removal of fructosamines, which are the products of a spontaneous reaction of glucose with amines. Fructosamine 106-119 fructosamine 3 kinase Homo sapiens 0-21 16670083-1 2006 Fructosamine-3-kinase (FN3K) is a recently described protein-repair enzyme responsible for the removal of fructosamines, which are the products of a spontaneous reaction of glucose with amines. Fructosamine 106-119 fructosamine 3 kinase Homo sapiens 23-27 16099335-7 2005 Significant correlations were found between PPK and fructosamine levels in all diabetic patients (R(S)=+0.57 p <0.001), in diabetic patients without retinopathy (R(S)=+0.61, p <0.05), and in diabetic patients with retinopathy (R(S)=+0.62, p <0.005). Fructosamine 52-64 kallikrein B1 Homo sapiens 44-47 16523184-1 2006 BACKGROUND: Part of the fructosamines that are bound to intracellular proteins are repaired by fructosamine 3-kinase (FN3K). Fructosamine 24-37 fructosamine 3 kinase Homo sapiens 95-116 16523184-1 2006 BACKGROUND: Part of the fructosamines that are bound to intracellular proteins are repaired by fructosamine 3-kinase (FN3K). Fructosamine 24-37 fructosamine 3 kinase Homo sapiens 118-122 15996257-9 2005 Insulin independent subjects demonstrated normalization of HbA1c, fructosamine and Mean Amplitude of Glycemic Excursions (MAGE) values. Fructosamine 66-78 insulin Homo sapiens 0-7 15705060-1 2005 FN3K (fructosamine 3-kinase) is a mammalian enzyme that catalyses the phosphorylation of fructosamines, which thereby becomes unstable and detaches from proteins. Fructosamine 89-102 fructosamine 3 kinase Homo sapiens 0-4 15619291-5 2005 The insulin requirement significantly decreased from 0.93 +/- 0.2 IU/kg to 0.73 +/- 0.2 IU/kg of body weight and to 0.74 +/- 0.15 IU/kg of body weight, respectively, while no significant differences were observed for BMI SDS, fructosamine and severe hypoglycaemic events. Fructosamine 226-238 insulin Homo sapiens 4-11 15705060-1 2005 FN3K (fructosamine 3-kinase) is a mammalian enzyme that catalyses the phosphorylation of fructosamines, which thereby becomes unstable and detaches from proteins. Fructosamine 89-102 fructosamine 3 kinase Homo sapiens 6-27 15705060-2 2005 The homologous mammalian enzyme, FN3K-RP (FN3K-related protein), does not phosphorylate fructosamines but ribulosamines, which are probably formed through a spontaneous reaction of amines with ribose 5-phosphate, an intermediate of the pentose-phosphate pathway and the Calvin cycle. Fructosamine 88-101 fructosamine 3 kinase related protein Homo sapiens 33-40 15705060-2 2005 The homologous mammalian enzyme, FN3K-RP (FN3K-related protein), does not phosphorylate fructosamines but ribulosamines, which are probably formed through a spontaneous reaction of amines with ribose 5-phosphate, an intermediate of the pentose-phosphate pathway and the Calvin cycle. Fructosamine 88-101 fructosamine 3 kinase related protein Homo sapiens 42-62 15922110-0 2005 Intrinsic toxicity of glucose, due to non-enzymatic glycation, is controlled in-vivo by deglycation systems including: FN3K-mediated deglycation of fructosamines and transglycation of aldosamines. Fructosamine 148-161 fructosamine 3 kinase Homo sapiens 119-123 15828742-3 2005 The majority of the dogs were receiving insulin therapy once a day, but in the dogs receiving insulin injections twice a day there was a trend for lower serum fructosamine concentrations, suggesting better glycaemic control. Fructosamine 159-171 insulin Canis lupus familiaris 94-101 15579799-8 2004 Fructosamine and hemoglobin A1c declined significantly with intensive insulin therapy, and insulin requirements decreased over time. Fructosamine 0-12 insulin Homo sapiens 70-77 15137908-1 2004 Fructosamine 3-kinase (FN3K), an enzyme initially identified in erythrocytes, catalyses the phosphorylation of fructosamines on their third carbon, leading to their destabilization and their removal from protein. Fructosamine 111-124 fructosamine 3 kinase Homo sapiens 0-21 15331600-1 2004 Fructosamine 3-kinase (FN3K) and FN3K-related protein (FN3K-RP) catalyze the phosphorylation of the Amadori products ribulosamines, psicosamines, and, in the case of FN3K, fructosamines. Fructosamine 172-185 fructosamine 3 kinase Gallus gallus 0-21 15331600-1 2004 Fructosamine 3-kinase (FN3K) and FN3K-related protein (FN3K-RP) catalyze the phosphorylation of the Amadori products ribulosamines, psicosamines, and, in the case of FN3K, fructosamines. Fructosamine 172-185 fructosamine 3 kinase Gallus gallus 23-27 15331600-1 2004 Fructosamine 3-kinase (FN3K) and FN3K-related protein (FN3K-RP) catalyze the phosphorylation of the Amadori products ribulosamines, psicosamines, and, in the case of FN3K, fructosamines. Fructosamine 172-185 fructosamine 3 kinase related protein Gallus gallus 33-53 15331600-1 2004 Fructosamine 3-kinase (FN3K) and FN3K-related protein (FN3K-RP) catalyze the phosphorylation of the Amadori products ribulosamines, psicosamines, and, in the case of FN3K, fructosamines. Fructosamine 172-185 fructosamine 3 kinase related protein Gallus gallus 55-62 15331600-1 2004 Fructosamine 3-kinase (FN3K) and FN3K-related protein (FN3K-RP) catalyze the phosphorylation of the Amadori products ribulosamines, psicosamines, and, in the case of FN3K, fructosamines. Fructosamine 172-185 fructosamine 3 kinase Gallus gallus 33-37 15137908-1 2004 Fructosamine 3-kinase (FN3K), an enzyme initially identified in erythrocytes, catalyses the phosphorylation of fructosamines on their third carbon, leading to their destabilization and their removal from protein. Fructosamine 111-124 fructosamine 3 kinase Homo sapiens 23-27 15137908-2 2004 We show that human erythrocytes also contain FN3K-related protein (FN3K-RP), an enzyme that phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of their sugar moiety. Fructosamine 147-160 fructosamine 3 kinase related protein Homo sapiens 67-74 14641062-4 2003 Fructosamine 3-kinase phosphorylates with high affinity both low-molecular-mass and protein-bound fructosamines on the third carbon of their deoxyfructose moiety, leading to the formation of fructosamine 3-phosphates. Fructosamine 98-111 fructosamine 3 kinase Homo sapiens 0-21 15102834-0 2004 Identification of fructosamine residues deglycated by fructosamine-3-kinase in human hemoglobin. Fructosamine 18-30 fructosamine 3 kinase Homo sapiens 54-75 15102834-1 2004 Fructosamine-3-kinase (FN3K) phosphorylates fructosamine residues, leading to their destabilization and their shedding from protein. Fructosamine 44-56 fructosamine 3 kinase Homo sapiens 0-21 15102834-1 2004 Fructosamine-3-kinase (FN3K) phosphorylates fructosamine residues, leading to their destabilization and their shedding from protein. Fructosamine 44-56 fructosamine 3 kinase Homo sapiens 23-27 15102834-3 2004 The aim of this work was to identify the fructosamine residues on hemoglobin that are removed as a result of the action of FN3K in intact erythrocytes. Fructosamine 41-53 fructosamine 3 kinase Homo sapiens 123-127 15126009-0 2004 Gln27Glu polymorphism of the beta2 adrenergic receptor gene in healthy Japanese men is associated with the change of fructosamine level caused by exercise. Fructosamine 117-129 adrenoceptor beta 2 Homo sapiens 29-54 14696106-6 2004 For women in the highest quartile of c-peptide or of c-peptide:fructosamine compared to those in the lowest quartile, the odds ratios (ORs) for hyperplasia were 3.0 (95% confidence interval [CI] 1.4-6.5) and 3.3 (95% CI 1.5-7.3), respectively (p trend = 0.02 and 0.02, respectively). Fructosamine 63-75 insulin Homo sapiens 53-62 15197409-11 2004 In male diabetic fatty Zucker rats, PYY[3-36] infused for 4 weeks reduced HbA1c and fructosamine (ED(50)"s 30 and 44 microg/kg/day). Fructosamine 84-96 peptide YY Rattus norvegicus 36-39 15036419-6 2004 The "young" elastin had the highest capacity to form both fructosamine and AGEs under glycation in vitro. Fructosamine 58-70 elastin Homo sapiens 12-19 15366734-2 2004 Quite to the contrary, a mammalian enzyme, fructosamine 3-kinase, has recently been identified, which phosphorylates fructosamines on their third carbon, making them unstable and leading to their shedding from proteins. Fructosamine 117-130 fructosamine 3 kinase Homo sapiens 43-64 12219718-4 2002 Decreased insulin promotes lipolysis and moderate hyperlipidemia, which can lead to falsely lowered fructosamine levels, impaired renal circulation, and atherosclerosis. Fructosamine 100-112 insulin Canis lupus familiaris 10-17 14633848-0 2003 A mammalian protein homologous to fructosamine-3-kinase is a ketosamine-3-kinase acting on psicosamines and ribulosamines but not on fructosamines. Fructosamine 133-146 fructosamine 3 kinase Homo sapiens 34-55 14633848-1 2003 Fructosamine-3-kinase (FN3K) is an enzyme that appears to be responsible for the removal of fructosamines from proteins. Fructosamine 92-105 fructosamine 3 kinase Homo sapiens 0-21 14633848-1 2003 Fructosamine-3-kinase (FN3K) is an enzyme that appears to be responsible for the removal of fructosamines from proteins. Fructosamine 92-105 fructosamine 3 kinase Homo sapiens 23-27 14633848-11 2003 This role is shared by fructosamine-3-kinase (ketosamine-3-kinase 1), which has, in addition, the unique capacity to phosphorylate fructosamines. Fructosamine 131-144 fructosamine 3 kinase Homo sapiens 23-44 12591543-6 2003 With intensive insulin therapy, a trend to normalize parameters of glycemic control (HbA1c and fructosamine) was observed within subjects and on a group level. Fructosamine 95-107 insulin Homo sapiens 15-22 12062855-6 2002 In the Trp/Trp genotype of the beta3AR gene, the levels of serum leptin, FPG and fructosamine (FrAm) decreased significantly after the exercise program, but not in the Arg/Arg genotype. Fructosamine 81-93 adrenoceptor beta 3 Homo sapiens 31-38 12067822-3 2002 RESULTS: Insulin therapy resulted in a significant decrease in fasting glucose levels by 26%; glycated hemoglobin decreased by 17% and fructosamine values by 19%. Fructosamine 135-147 insulin Homo sapiens 9-16 11975663-1 2002 Fructosamine 3-kinase, which phosphorylates low-molecular-mass and protein-bound fructosamines on the third carbon of their deoxyfructose moiety, is quite active in erythrocytes, and was proposed to initiate a process removing fructosamine residues from proteins. Fructosamine 81-94 fructosamine 3 kinase Homo sapiens 0-21 11975663-1 2002 Fructosamine 3-kinase, which phosphorylates low-molecular-mass and protein-bound fructosamines on the third carbon of their deoxyfructose moiety, is quite active in erythrocytes, and was proposed to initiate a process removing fructosamine residues from proteins. Fructosamine 81-93 fructosamine 3 kinase Homo sapiens 0-21 11762518-7 2001 This study indicates that the addition of weekly fructosamine values to daily blood glucose values provides both the patient and clinician valuable information to evaluate the impact of dietary, exercise, and medication therapy changes on glycemic control by bridging the existing gap between daily blood glucose values and quarterly HbA1c confirmation of intervention results. Fructosamine 49-61 hemoglobin subunit alpha 1 Homo sapiens 334-338 10555094-10 1999 CONCLUSIONS: Fructosamine may be a useful adjunctive test for management of outpatients with diabetes in situations where it is not practical to obtain same-day glycoHb concentrations, for patients less compliant with home glucose monitoring, or where recent changes in insulin dose or clinical presentation might not be reflected in the glycoHb levels. Fructosamine 13-25 insulin Homo sapiens 270-277 19746667-9 2001 Results of regression analysis indicated that exogenous insulin could be reduced by over 50% with no loss in glucose control, as measured by serum fructosamine. Fructosamine 147-159 insulin Felis catus 56-63 11259960-6 2001 The first year of audit was associated with a reduction in mean fructosamine from 369 +/- 85 micromol L-1 to 321 +/- 65 micromol L-1 and this was sustained for a further 3 years. Fructosamine 64-76 immunoglobulin kappa variable 1-16 Homo sapiens 102-105 11194244-4 2001 RESULTS: Insulin aspart and buffered regular human insulin were both effective in controlling average daily blood glucose levels (8.2 +/- 1.9 and 8.5 +/- 2.1 mmol/l, respectively) (mean +/- SD) and maintaining serum fructosamine (343 +/- 25.7 and 336 +/- 27.4 micromol/l) and HbA1c (6.9 +/- 0.6 and 7.1 +/- 0.6%) levels. Fructosamine 216-228 insulin Homo sapiens 9-16 11194244-4 2001 RESULTS: Insulin aspart and buffered regular human insulin were both effective in controlling average daily blood glucose levels (8.2 +/- 1.9 and 8.5 +/- 2.1 mmol/l, respectively) (mean +/- SD) and maintaining serum fructosamine (343 +/- 25.7 and 336 +/- 27.4 micromol/l) and HbA1c (6.9 +/- 0.6 and 7.1 +/- 0.6%) levels. Fructosamine 216-228 insulin Homo sapiens 51-58 10947883-16 2000 CONCLUSIONS: Our data indicate that TNF-alpha plasma levels are increased in type 1 diabetes mellitus and reveal a significant association with metabolic long-term control parameters, HbA1c and fructosamine for glycaemic control, and HDL cholesterol for triglyceride metabolism, as well with lipid peroxidation. Fructosamine 194-206 tumor necrosis factor Homo sapiens 36-45 10615819-7 1999 In the diabetic group the significant positive correlation between EPO and maternal HbA1c and fructosamine levels was found as well as between EPO and fetal fructosamine levels. Fructosamine 94-106 erythropoietin Homo sapiens 67-70 10615819-7 1999 In the diabetic group the significant positive correlation between EPO and maternal HbA1c and fructosamine levels was found as well as between EPO and fetal fructosamine levels. Fructosamine 94-106 hemoglobin subunit alpha 1 Homo sapiens 84-88 10615819-7 1999 In the diabetic group the significant positive correlation between EPO and maternal HbA1c and fructosamine levels was found as well as between EPO and fetal fructosamine levels. Fructosamine 157-169 erythropoietin Homo sapiens 143-146 10615821-4 1999 That was found a significant positive correlation between Ic and maternal HbA1c and fructosamine levels as well as between Ic and neonatal birthweight in the diabetic group. Fructosamine 84-96 hemoglobin subunit alpha 1 Homo sapiens 74-78 10452282-9 1999 When 24 h collections (expressed as NAG/l) were used, the results correlated well with HbA1(a-c) and fructosamine. Fructosamine 101-113 O-GlcNAcase Homo sapiens 36-39 9451409-5 1997 The relationship between the two measures was assessed by determining 95% prediction intervals for HbA1C from the regression equation relating mean HbA1C and fructosamine. Fructosamine 158-170 hemoglobin subunit alpha 1 Homo sapiens 99-103 9592639-5 1998 Triglyceride concentrations were associated positively and significantly with the insulin dose of both boys and girls, after adjustment for age, pubertal stage, diabetes duration, and metabolic control (fructosamine levels). Fructosamine 203-215 insulin Homo sapiens 82-89 9562242-6 1998 A decrease in the specific activity of ALP was associated both with an increase in fructosamine levels and with the appearance of AGE-characteristic fluorescence. Fructosamine 83-95 alkaline phosphatase, placental Homo sapiens 39-42 9547902-3 1998 HbA1c correlated better (r = 0.573) with mean blood glucose (MBG) concentration than did fructosamine Test Plus (r = 0.347), even after correction for total protein concentration (r = 0.463), while there was no significant correlation with the original fructosamine method (r = 0.201). Fructosamine 253-265 hemoglobin subunit alpha 1 Homo sapiens 0-4 9187409-4 1997 The percentage of urinary glycated transferrin (serum %G-transferrin) positively correlated with serum fructosamine concentrations and the percentage of serum glycated albumin (serum %G-albumin) in all subjects. Fructosamine 103-115 transferrin Homo sapiens 35-46 9187409-4 1997 The percentage of urinary glycated transferrin (serum %G-transferrin) positively correlated with serum fructosamine concentrations and the percentage of serum glycated albumin (serum %G-albumin) in all subjects. Fructosamine 103-115 transferrin Homo sapiens 57-68 9288551-6 1997 After 8-10 weeks of complementary insulin therapy, OHA patients (n = 33) improved both the glycemic control (HbA1c: 10.5 +/- 1.78% vs. 9.0 +/- 1.75%, p < 0.001) and fructosamine: 4.0 +/- 0.85 mmol/l vs. 3.5 +/- 0.76 mmol/l, p < 0.001) and most of the lipid parameters (decreased serum triglyceride: 5.8 +/- 5.64 mmol/l vs. 3.6 +/- 4.69 mmol/l, p < 0.001, total cholesterol/HDL-cholesterol: 6.8 +/- 3.13 vs. 5.6 +/- 2.23, p < 0.01 and increased HDL-cholesterol: 1.0 +/- 0.30 mmol/l vs. 1.2 +/- 0.30 mmol/l, p < 0.001, apo AI: 1.6 +/- 0.26 g/l vs. 1.8 +/- 0.28 g/l, p < 0.001, LpAI particles: 0.6 +/- 0.1 g/l vs. 0.7 +/- 0.12 g/l, p < 0.001 and LDL-cholesterol/apo B: 2.1 +/- 0.67 vs. 2.7 +/- 0.67, p < 0.001). Fructosamine 168-180 insulin Homo sapiens 34-41