PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
30651282-1	2019	Mutations in NCF1 (p47phox) cause autosomal recessive chronic granulomatous disease (CGD) with abnormal dihydrorhodamine (DHR) assay and absent p47phox protein.	dhr	122-125	neutrophil cytosolic factor 1	Homo sapiens	13-17
30651282-1	2019	Mutations in NCF1 (p47phox) cause autosomal recessive chronic granulomatous disease (CGD) with abnormal dihydrorhodamine (DHR) assay and absent p47phox protein.	dhr	122-125	neutrophil cytosolic factor 1	Homo sapiens	19-26
30651282-1	2019	Mutations in NCF1 (p47phox) cause autosomal recessive chronic granulomatous disease (CGD) with abnormal dihydrorhodamine (DHR) assay and absent p47phox protein.	dhr	122-125	cytochrome b-245 beta chain	Homo sapiens	85-88
30149421-8	2018	The blood lactate, serum cortisol, myoglobin, and plasma interleukin-6 concentrations were significantly higher in the DHR group than in the LR group after exercise (P < 0.05 for all variables).	dhr	119-122	interleukin 6	Homo sapiens	57-70
30213469-10	2019	DHR results showed weak negative correlations with serum leptin (p=0.177) and with BMI Z score (p=0.109).	dhr	0-3	leptin	Homo sapiens	57-63
24048912-9	2014	While plasma MMP-9 changes may be detectable in the systemic circulation after DHR, they are small and do not correspond to other markers of damage.	dhr	79-82	matrix metallopeptidase 9	Homo sapiens	13-18
19458962-3	2009	Muscle injury was observed at 96 h (3.3-fold) and 120 h (3.7-fold) post-DHR (P < 0.01) and elevated MCadherin expression at 72 h (2.7-fold), 96 h (2.4-fold) post-DHR (P < 0.05) and 120 h (3.3-fold) post-DHR (P < 0.01).	dhr	165-168	cadherin 15	Mus musculus	103-112
23963660-8	2014	LEF1 protein increased 6 days (5-fold) post-DHR.	dhr	44-47	lymphoid enhancer binding factor 1	Mus musculus	0-4
23827747-7	2013	Neutrophil function test with dihydrorhodamine (DHR) showed X linked-CGD pattern and molecular analysis of DNAshowed a splice site mutation (c.338-1G > A) in CYBB gene.	dhr	48-51	cytochrome b-245 beta chain	Homo sapiens	161-165
23106791-7	2013	The sensitivity of combined measurement of drug-specific IFN-gamma and IL-4 cytokines during acute DHR was better than LPA (82% vs. 50%), but all assays were less sensitive during the recovery phase.	dhr	99-102	interferon gamma	Homo sapiens	57-66
23106791-7	2013	The sensitivity of combined measurement of drug-specific IFN-gamma and IL-4 cytokines during acute DHR was better than LPA (82% vs. 50%), but all assays were less sensitive during the recovery phase.	dhr	99-102	interleukin 4	Homo sapiens	71-75
21372002-7	2011	The MPO-NAA-induced production of reactive oxygen species was assessed using oxidation of dihydrorhodamine (DHR) to rhodamine.	dhr	108-111	myeloperoxidase	Homo sapiens	4-7
19458962-3	2009	Muscle injury was observed at 96 h (3.3-fold) and 120 h (3.7-fold) post-DHR (P < 0.01) and elevated MCadherin expression at 72 h (2.7-fold), 96 h (2.4-fold) post-DHR (P < 0.05) and 120 h (3.3-fold) post-DHR (P < 0.01).	dhr	165-168	cadherin 15	Mus musculus	103-112
15289284-14	2004	GEA 3162 and SIN-1 oxidised the O(2)(-)- and ONOO(-)-sensitive dye, dihydrorhodamine 123 (DHR 123; 1 microm), suggesting that ONOO(-) released from these compounds is responsible for oxidation of DHR 123.	dhr	90-93	MAPK associated protein 1	Homo sapiens	13-18
15289284-14	2004	GEA 3162 and SIN-1 oxidised the O(2)(-)- and ONOO(-)-sensitive dye, dihydrorhodamine 123 (DHR 123; 1 microm), suggesting that ONOO(-) released from these compounds is responsible for oxidation of DHR 123.	dhr	196-199	MAPK associated protein 1	Homo sapiens	13-18
8139258-12	1994	In contrast, DHR was characterized by the dual asynchronous expression of both E-selectin and VCAM-1.	dhr	13-16	selectin E	Homo sapiens	79-89
15010533-7	2004	Inhibition of the Fenton reaction by the.OH scavenger DHR attenuated HIF-prolyl hydroxylase activity and interaction with von Hippel-Lindau protein, leading to enhanced HIF-1alpha levels, HIF-1alpha transactivation, and activated expression of the HIF-1 target genes plasminogen activator inhibitor 1 and heme oxygenase 1.	dhr	54-57	hypoxia inducible factor 1 subunit alpha	Homo sapiens	169-179
15010533-7	2004	Inhibition of the Fenton reaction by the.OH scavenger DHR attenuated HIF-prolyl hydroxylase activity and interaction with von Hippel-Lindau protein, leading to enhanced HIF-1alpha levels, HIF-1alpha transactivation, and activated expression of the HIF-1 target genes plasminogen activator inhibitor 1 and heme oxygenase 1.	dhr	54-57	hypoxia inducible factor 1 subunit alpha	Homo sapiens	188-198
15010533-7	2004	Inhibition of the Fenton reaction by the.OH scavenger DHR attenuated HIF-prolyl hydroxylase activity and interaction with von Hippel-Lindau protein, leading to enhanced HIF-1alpha levels, HIF-1alpha transactivation, and activated expression of the HIF-1 target genes plasminogen activator inhibitor 1 and heme oxygenase 1.	dhr	54-57	hypoxia inducible factor 1 subunit alpha	Homo sapiens	169-174
15010533-7	2004	Inhibition of the Fenton reaction by the.OH scavenger DHR attenuated HIF-prolyl hydroxylase activity and interaction with von Hippel-Lindau protein, leading to enhanced HIF-1alpha levels, HIF-1alpha transactivation, and activated expression of the HIF-1 target genes plasminogen activator inhibitor 1 and heme oxygenase 1.	dhr	54-57	serpin family E member 1	Homo sapiens	267-300
15010533-7	2004	Inhibition of the Fenton reaction by the.OH scavenger DHR attenuated HIF-prolyl hydroxylase activity and interaction with von Hippel-Lindau protein, leading to enhanced HIF-1alpha levels, HIF-1alpha transactivation, and activated expression of the HIF-1 target genes plasminogen activator inhibitor 1 and heme oxygenase 1.	dhr	54-57	heme oxygenase 1	Homo sapiens	305-321
15010533-8	2004	Further,.OH scavenging appeared to enhance redox factor 1 (Ref-1) binding and, thus, recruitment of p300 to the transactivation domain C because mutation of the Ref-1 binding site cysteine 800 abolished DHR-induced transactivation.	dhr	203-206	E1A binding protein p300	Homo sapiens	100-104
15010533-8	2004	Further,.OH scavenging appeared to enhance redox factor 1 (Ref-1) binding and, thus, recruitment of p300 to the transactivation domain C because mutation of the Ref-1 binding site cysteine 800 abolished DHR-induced transactivation.	dhr	203-206	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	161-166
14501952-11	2003	The MPO activity in lung, blood DHR 123 oxidation level, and lung permeability increased up to 2-fold, 4-fold, and 2.5-fold after burn.	dhr	32-35	myeloperoxidase	Rattus norvegicus	4-7
9706741-4	1998	We assessed the ability of myoglobin (Mb) or hemoglobin (Hb) to oxidize dihydrorhodamine (DHR) to rhodamine (RH) in the presence of O2-/H2O2 and/or NO.	dhr	90-93	myoglobin	Homo sapiens	27-36
8786425-3	1996	CASK is composed of an N-terminal Ca2+, calmodulin-dependent protein kinase sequence and a C-terminal region that is similar to the intercellular junction proteins dlg-A, PSD95/SAP90, SAP97, Z01, and Z02 and that contains DHR-, SH3-, and guanylate kinase domains.	dhr	222-225	calcium/calmodulin dependent serine protein kinase	Homo sapiens	0-4
10452962-1	1999	Isolated copper/zinc superoxide dismutase (Cu/Zn-SOD) or manganese superoxide dismutase (Mn-SOD) together with hydrogen peroxide (H(2)O(2)) caused rapid breakdown of nitric oxide (NO) and production of peroxynitrite (ONOO(-)) indicated by the oxidation of dihydrorhodamine-1,2,3 (DHR) to rhodamine-1,2,3.	dhr	280-283	superoxide dismutase 2	Homo sapiens	57-87
10452962-1	1999	Isolated copper/zinc superoxide dismutase (Cu/Zn-SOD) or manganese superoxide dismutase (Mn-SOD) together with hydrogen peroxide (H(2)O(2)) caused rapid breakdown of nitric oxide (NO) and production of peroxynitrite (ONOO(-)) indicated by the oxidation of dihydrorhodamine-1,2,3 (DHR) to rhodamine-1,2,3.	dhr	280-283	superoxide dismutase 2	Homo sapiens	89-95
8831592-7	1996	Treatment with an anti-CD18 antibody blocked irradiation-induced leukocyte adherence and emigration and prevented the DHR-123 oxidation, normally observed at 6 hours, with a partial attenuation of DHR-123 oxidation at 2 hours.	dhr	118-121	integrin subunit beta 2	Rattus norvegicus	23-27
8831592-7	1996	Treatment with an anti-CD18 antibody blocked irradiation-induced leukocyte adherence and emigration and prevented the DHR-123 oxidation, normally observed at 6 hours, with a partial attenuation of DHR-123 oxidation at 2 hours.	dhr	197-200	integrin subunit beta 2	Rattus norvegicus	23-27
8139258-12	1994	In contrast, DHR was characterized by the dual asynchronous expression of both E-selectin and VCAM-1.	dhr	13-16	vascular cell adhesion molecule 1	Homo sapiens	94-100
35344128-1	2022	PURPOSE: This is a functional characterization of a novel CYBA variant associated with normal DHR flow cytometry.	dhr	94-97	cytochrome b-245 alpha chain	Homo sapiens	58-62