PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
34497913-3	2021	The significant amplifying actions of two PAHs, dibenzo(a,l)pyrene (DB(a,l)P) at 50 nM and dibenzo(a,i)pyrene (DB(a,i)P) at 2 muM for 48 h, for IL-8 protein release induced by mite antigens in epithelial cells were observed for the first time.	dibenzo(a,l)pyrene	48-66	C-X-C motif chemokine ligand 8	Homo sapiens	144-148
34497913-3	2021	The significant amplifying actions of two PAHs, dibenzo(a,l)pyrene (DB(a,l)P) at 50 nM and dibenzo(a,i)pyrene (DB(a,i)P) at 2 muM for 48 h, for IL-8 protein release induced by mite antigens in epithelial cells were observed for the first time.	dibenzo(a,l)pyrene	68-76	C-X-C motif chemokine ligand 8	Homo sapiens	144-148
26990437-0	2017	Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.	dibenzo(a,l)pyrene	0-22	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	67-73
31838185-3	2020	The high cytotoxicity of DBC was observed after 72 h incubation (IC50 = 0.06 muM).	dibenzo(a,l)pyrene	25-28	latexin	Homo sapiens	77-80
31838185-10	2020	The DNA-PK inhibitor, NU7026 increases cell viability after exposure to DBC and reduces DNA damage, what indicates an important role of the sensor kinase in mediating the effect.	dibenzo(a,l)pyrene	72-75	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	4-10
31433626-3	2019	Here we report for the first time that the oral treatment of lacI mice with a combination of tobacco smoke carcinogens, DB[a,l]P and N"-nitrosonornicotine (NNN), induces a higher fraction of mutations than expected from a simple sum of their induced individual mutation fractions, and a change in the mutational profile compared with that expected from the sum of the individual agents.	dibenzo(a,l)pyrene	120-128	tissue factor pathway inhibitor	Mus musculus	61-65
29073177-0	2017	Hypomethylated Fgf3 is a potential biomarker for early detection of oral cancer in mice treated with the tobacco carcinogen dibenzo[def,p]chrysene.	dibenzo(a,l)pyrene	124-146	fibroblast growth factor 3	Mus musculus	15-19
28374118-1	2018	In the proposed work, we have explicated the mechanism of dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) modulated cell proliferation by assessing the plausible binding with CASPASES, BAX, Bcl-2, MDM2, p53, p21, p16, CylinD1-CDK4 complex, CylinE1-CDK2 complex, H-Ras, K-Ras, BRCA1, and BRCA2 through exploiting the inherent potential of AutoDock Tools 4.0.	dibenzo(a,l)pyrene	58-76	D-box binding PAR bZIP transcription factor	Homo sapiens	78-81
28374118-1	2018	In the proposed work, we have explicated the mechanism of dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) modulated cell proliferation by assessing the plausible binding with CASPASES, BAX, Bcl-2, MDM2, p53, p21, p16, CylinD1-CDK4 complex, CylinE1-CDK2 complex, H-Ras, K-Ras, BRCA1, and BRCA2 through exploiting the inherent potential of AutoDock Tools 4.0.	dibenzo(a,l)pyrene	58-76	BCL2 associated X, apoptosis regulator	Homo sapiens	186-189
28374118-1	2018	In the proposed work, we have explicated the mechanism of dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) modulated cell proliferation by assessing the plausible binding with CASPASES, BAX, Bcl-2, MDM2, p53, p21, p16, CylinD1-CDK4 complex, CylinE1-CDK2 complex, H-Ras, K-Ras, BRCA1, and BRCA2 through exploiting the inherent potential of AutoDock Tools 4.0.	dibenzo(a,l)pyrene	58-76	MDM2 proto-oncogene	Homo sapiens	198-202
28374118-1	2018	In the proposed work, we have explicated the mechanism of dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) modulated cell proliferation by assessing the plausible binding with CASPASES, BAX, Bcl-2, MDM2, p53, p21, p16, CylinD1-CDK4 complex, CylinE1-CDK2 complex, H-Ras, K-Ras, BRCA1, and BRCA2 through exploiting the inherent potential of AutoDock Tools 4.0.	dibenzo(a,l)pyrene	58-76	tumor protein p53	Homo sapiens	204-207
28374118-1	2018	In the proposed work, we have explicated the mechanism of dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) modulated cell proliferation by assessing the plausible binding with CASPASES, BAX, Bcl-2, MDM2, p53, p21, p16, CylinD1-CDK4 complex, CylinE1-CDK2 complex, H-Ras, K-Ras, BRCA1, and BRCA2 through exploiting the inherent potential of AutoDock Tools 4.0.	dibenzo(a,l)pyrene	58-76	H3 histone pseudogene 16	Homo sapiens	209-212
28374118-1	2018	In the proposed work, we have explicated the mechanism of dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) modulated cell proliferation by assessing the plausible binding with CASPASES, BAX, Bcl-2, MDM2, p53, p21, p16, CylinD1-CDK4 complex, CylinE1-CDK2 complex, H-Ras, K-Ras, BRCA1, and BRCA2 through exploiting the inherent potential of AutoDock Tools 4.0.	dibenzo(a,l)pyrene	58-76	cyclin dependent kinase inhibitor 2A	Homo sapiens	214-217
28374118-1	2018	In the proposed work, we have explicated the mechanism of dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) modulated cell proliferation by assessing the plausible binding with CASPASES, BAX, Bcl-2, MDM2, p53, p21, p16, CylinD1-CDK4 complex, CylinE1-CDK2 complex, H-Ras, K-Ras, BRCA1, and BRCA2 through exploiting the inherent potential of AutoDock Tools 4.0.	dibenzo(a,l)pyrene	58-76	cyclin dependent kinase 4	Homo sapiens	227-231
28374118-1	2018	In the proposed work, we have explicated the mechanism of dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) modulated cell proliferation by assessing the plausible binding with CASPASES, BAX, Bcl-2, MDM2, p53, p21, p16, CylinD1-CDK4 complex, CylinE1-CDK2 complex, H-Ras, K-Ras, BRCA1, and BRCA2 through exploiting the inherent potential of AutoDock Tools 4.0.	dibenzo(a,l)pyrene	58-76	cyclin dependent kinase 2	Homo sapiens	249-253
28374118-1	2018	In the proposed work, we have explicated the mechanism of dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) modulated cell proliferation by assessing the plausible binding with CASPASES, BAX, Bcl-2, MDM2, p53, p21, p16, CylinD1-CDK4 complex, CylinE1-CDK2 complex, H-Ras, K-Ras, BRCA1, and BRCA2 through exploiting the inherent potential of AutoDock Tools 4.0.	dibenzo(a,l)pyrene	58-76	HRas proto-oncogene, GTPase	Homo sapiens	263-268
28374118-1	2018	In the proposed work, we have explicated the mechanism of dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) modulated cell proliferation by assessing the plausible binding with CASPASES, BAX, Bcl-2, MDM2, p53, p21, p16, CylinD1-CDK4 complex, CylinE1-CDK2 complex, H-Ras, K-Ras, BRCA1, and BRCA2 through exploiting the inherent potential of AutoDock Tools 4.0.	dibenzo(a,l)pyrene	58-76	KRAS proto-oncogene, GTPase	Homo sapiens	270-275
28374118-1	2018	In the proposed work, we have explicated the mechanism of dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) modulated cell proliferation by assessing the plausible binding with CASPASES, BAX, Bcl-2, MDM2, p53, p21, p16, CylinD1-CDK4 complex, CylinE1-CDK2 complex, H-Ras, K-Ras, BRCA1, and BRCA2 through exploiting the inherent potential of AutoDock Tools 4.0.	dibenzo(a,l)pyrene	58-76	BRCA1 DNA repair associated	Homo sapiens	277-282
28374118-1	2018	In the proposed work, we have explicated the mechanism of dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) modulated cell proliferation by assessing the plausible binding with CASPASES, BAX, Bcl-2, MDM2, p53, p21, p16, CylinD1-CDK4 complex, CylinE1-CDK2 complex, H-Ras, K-Ras, BRCA1, and BRCA2 through exploiting the inherent potential of AutoDock Tools 4.0.	dibenzo(a,l)pyrene	58-76	BRCA2 DNA repair associated	Homo sapiens	288-293
29068672-3	2017	Here we extend this work to protection by BE against DNA adduct formation induced by dibenzo-[a,l]-pyrene (DBP) in a human oral leukoplakia cell line (MSK) and to a second carcinogen, UV light.	dibenzo(a,l)pyrene	85-105	D-box binding PAR bZIP transcription factor	Homo sapiens	107-110
26990437-0	2017	Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.	dibenzo(a,l)pyrene	0-22	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	88-94
26990437-2	2017	Utilizing a mouse model, null for Cyp1b1 and expressing human CYP1B1, we tested the hypothesis that hCYP1B1 is important for dibenzo[def,p]chrysene (DBC) transplacental carcinogenesis.	dibenzo(a,l)pyrene	125-147	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	100-107
26990437-2	2017	Utilizing a mouse model, null for Cyp1b1 and expressing human CYP1B1, we tested the hypothesis that hCYP1B1 is important for dibenzo[def,p]chrysene (DBC) transplacental carcinogenesis.	dibenzo(a,l)pyrene	149-152	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	100-107
28959603-0	2016	Differential cellular metabolite alterations in HaCaT cells caused by exposure to the aryl hydrocarbon receptor-binding polycyclic aromatic hydrocarbons chrysene, benzo[a]pyrene and dibenzo[a,l]pyrene.	dibenzo(a,l)pyrene	182-200	aryl hydrocarbon receptor	Homo sapiens	86-111
25794985-1	2015	Dibenzo[a,l]pyrene (DBP) has been found to be the most potent carcinogen of the polycyclic aromatic hydrocarbons (PAHs).	dibenzo(a,l)pyrene	0-18	D-box binding PAR bZIP transcription factor	Homo sapiens	20-23
26338538-0	2015	The influence of ATM, ATR, DNA-PK inhibitors on the cytotoxic and genotoxic effects of dibenzo[def,p]chrysene on human hepatocellular cancer cell line HepG2.	dibenzo(a,l)pyrene	87-109	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	27-33
25868132-0	2015	Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS.	dibenzo(a,l)pyrene	12-34	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	75-94
24769260-2	2014	Benzo[a]pyrene (B[a]P) is the prototypical carcinogenic PAH, and dibenzo[def,p]chrysene (DBC) is a less prevalent, but highly potent transplacental carcinogenic PAH.	dibenzo(a,l)pyrene	65-87	phenylalanine hydroxylase	Homo sapiens	161-164
24769260-2	2014	Benzo[a]pyrene (B[a]P) is the prototypical carcinogenic PAH, and dibenzo[def,p]chrysene (DBC) is a less prevalent, but highly potent transplacental carcinogenic PAH.	dibenzo(a,l)pyrene	89-92	phenylalanine hydroxylase	Homo sapiens	161-164
23151208-2	2013	There are numerous similarities between the patterns of cytochrome P-450 (P450) activation of DBC and its covalent binding to DNA and proteins with another polycyclic aromatic hydrocarbon (PAH), 7,12-dimethylbenz[a]anthracene (DMBA).	dibenzo(a,l)pyrene	94-97	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	56-78
24784728-5	2014	However, using electrophoretic mobility shift assays, we have found that XPC-RAD23B binding affinities of certain bulky lesions derived from metabolically activated polycyclic aromatic hydrocarbon compounds such as benzo[a]pyrene and dibenzo[a,l]pyrene, are not directly, or necessarily correlated with NER excision activities observed in cell-free extracts.	dibenzo(a,l)pyrene	234-252	XPC complex subunit, DNA damage recognition and repair factor	Homo sapiens	73-76
24784728-5	2014	However, using electrophoretic mobility shift assays, we have found that XPC-RAD23B binding affinities of certain bulky lesions derived from metabolically activated polycyclic aromatic hydrocarbon compounds such as benzo[a]pyrene and dibenzo[a,l]pyrene, are not directly, or necessarily correlated with NER excision activities observed in cell-free extracts.	dibenzo(a,l)pyrene	234-252	RAD23 homolog B, nucleotide excision repair protein	Homo sapiens	77-83
23994691-6	2014	This was discovered by correlation between the depurinating adducts formed in mouse skin by treatment with benzo[a]pyrene, dibenzo[a,l]pyrene or 7,12-dimethylbenz[a]anthracene and the site of mutations in the Harvey-ras oncogene in mouse skin papillomas initiated by one of these PAH.	dibenzo(a,l)pyrene	123-141	Harvey rat sarcoma virus oncogene	Mus musculus	209-219
23845848-6	2013	In the present study, a CYP3A4 reporter gene assay, requiring the overexpression of PXR, was used to investigate whether the PAH parent compounds BaP, benzo[c]phenanthrene (BcP) and dibenzo[a,l]pyrene (DBalP) as well as their corresponding phase I metabolites, the respective dihydrodiols and diol epoxides, can induce CYP3A4 promoter activity.	dibenzo(a,l)pyrene	182-200	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	24-30
23845848-6	2013	In the present study, a CYP3A4 reporter gene assay, requiring the overexpression of PXR, was used to investigate whether the PAH parent compounds BaP, benzo[c]phenanthrene (BcP) and dibenzo[a,l]pyrene (DBalP) as well as their corresponding phase I metabolites, the respective dihydrodiols and diol epoxides, can induce CYP3A4 promoter activity.	dibenzo(a,l)pyrene	202-207	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	24-30
23274566-6	2013	Predictions were within 1 log(2) fold change unit of microarray data, with the exception of the DBC treatment group, where the unexpected down-regulation of Cyp1b1 expression was predicted but did not reach statistical significance on the microarrays.	dibenzo(a,l)pyrene	96-99	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	157-163
21689667-1	2011	Benzo[a]pyrene (BP) and dibenzo[a,l]pyrene (DBP) are two polycyclic aromatic hydrocarbons (PAHs) that exhibit distinctly different mutagenicity and carcinogenicity profiles.	dibenzo(a,l)pyrene	24-42	D-box binding PAR bZIP transcription factor	Homo sapiens	44-47
22409540-6	2012	Signaling in HepG2 cells exposed to soil PAH extracts corresponding to 1 muM benzo[a]pyrene was similar to that of 0.1 muM dibenzo[a,l]pyrene, a highly carcinogenic PAH known to produce persistent DNA damage.	dibenzo(a,l)pyrene	123-141	phenylalanine hydroxylase	Homo sapiens	165-168
21780761-3	2011	Glucuronidation of major metabolites of DB[a,l]P by the uridine-5"-diphosphate glucuronosyltransferase (UGT) family of enzymes is an important route of detoxification of this pro-carcinogen.	dibenzo(a,l)pyrene	40-48	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	56-102
21780761-3	2011	Glucuronidation of major metabolites of DB[a,l]P by the uridine-5"-diphosphate glucuronosyltransferase (UGT) family of enzymes is an important route of detoxification of this pro-carcinogen.	dibenzo(a,l)pyrene	40-48	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	104-107
21632310-5	2011	Benzo[b]fluoranthene, dibenz[a,h]anthracene, benzo[a]pyrene, and dibenzo[a,l]pyrene were the most carcinogenic PAH species evaluated.	dibenzo(a,l)pyrene	65-83	phenylalanine hydroxylase	Homo sapiens	111-114
20389043-1	2010	Polycyclic aromatic hydrocarbons (PAH) such as dibenzo[a,l]pyrene (DBP) are wide-spread environmental pollutants most probably mutagenic and carcinogenic to humans.	dibenzo(a,l)pyrene	47-65	D-box binding PAR bZIP transcription factor	Homo sapiens	67-70
20634147-7	2010	The pGL3 plasmid containing a luciferase gene was damaged with diol epoxides of benzo[a]pyrene (B[a]P-DE), dibenzo[a,l]pyrene (DB[a,l]P-DE), benzo[g]chrysene (B[g]Ch-DE), and benzo[c]phenanthrene (B[c]Ph-DE).	dibenzo(a,l)pyrene	107-125	succinate dehydrogenase complex subunit C	Homo sapiens	4-8
19073876-1	2009	The carcinogenic potential of dibenzo[a,l]pyrene (DBP) has been well characterized in numerous animal models.	dibenzo(a,l)pyrene	30-48	D site albumin promoter binding protein	Mus musculus	50-53
19330882-0	2009	Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1.	dibenzo(a,l)pyrene	102-120	glutathione S-transferase pi 1	Homo sapiens	33-61
18573814-0	2008	Mutations induced by benzo[a]pyrene and dibenzo[a,l]pyrene in lacI transgenic B6C3F1 mouse lung result from stable DNA adducts.	dibenzo(a,l)pyrene	40-58	tissue factor pathway inhibitor	Mus musculus	62-66
19157061-3	2009	The focus of this present review lies on the influence of the molecular structure of two well-investigated chemical carcinogens from the group of polycyclic aromatic hydrocarbons (PAHs), benzo[a]pyrene (BP) and dibenzo[a,l]pyrene (DBP).	dibenzo(a,l)pyrene	211-229	D-box binding PAR bZIP transcription factor	Homo sapiens	231-234
19053321-1	2009	Dibenzo[a,l]pyrene (DBP) is the most potent tumor initiating polycyclic aromatic hydrocarbon tested to date in rodent tumor models.	dibenzo(a,l)pyrene	0-18	D-box binding PAR bZIP transcription factor	Homo sapiens	20-23
18848954-6	2008	We developed a pregnant mouse model in which exposure to the polycyclic aromatic hydrocarbon (PAH), dibenzo[a,l]pyrene (DBP), during late gestation, produces an aggressive T-cell lymphoma in offspring between 3 and 6 months of age.	dibenzo(a,l)pyrene	100-118	D site albumin promoter binding protein	Mus musculus	120-123
18635525-1	2008	Our laboratory recently developed a mouse model of transplacental induction of lymphoma, lung and liver cancer by the polycyclic aromatic hydrocarbon, dibenzo[a,l]pyrene (DBP).	dibenzo(a,l)pyrene	151-169	D site albumin promoter binding protein	Mus musculus	171-174
16704990-4	2006	The polycyclic aromatic hydrocarbon, dibenzo[a,l]pyrene (DBP), was administered to pregnant mice (15 mg/kg, gavage) on gestation day 17, and 2000 p.p.m.	dibenzo(a,l)pyrene	37-55	D site albumin promoter binding protein	Mus musculus	57-60
17932951-0	2008	Anti-diol epoxide of benzo[a]pyrene induces transient Mdm2 and p53 Ser15 phosphorylation, while anti-diol epoxide of dibenzo[a,l]pyrene induces a nontransient p53 Ser15 phosphorylation.	dibenzo(a,l)pyrene	117-135	tumor protein p53	Homo sapiens	159-162
17932951-1	2008	The polycyclic aromatic hydrocarbons (PAHs) dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) are environmental contaminants and potent carcinogens.	dibenzo(a,l)pyrene	44-62	D-box binding PAR bZIP transcription factor	Homo sapiens	64-67
18096571-0	2008	Mdm2 as a sensitive and mechanistically informative marker for genotoxicity induced by benzo[a]pyrene and dibenzo[a,l]pyrene.	dibenzo(a,l)pyrene	106-124	MDM2 proto-oncogene	Homo sapiens	0-4
18096571-7	2008	The more mutagenic dibenzo[a,l]pyrene as well as higher BP concentrations instead induced gammaH2AX and p53 Ser15 association with chromatin.	dibenzo(a,l)pyrene	19-37	tumor protein p53	Homo sapiens	104-107
17961608-9	2008	Finally, we studied effects of 2,4,3",5"-tetramethoxystilbene and fluoranthene, inhibitors of CYP1B1 activity, which plays a central role in metabolic activation of dibenzo[a,l]pyrene.	dibenzo(a,l)pyrene	165-183	cytochrome P450, family 1, subfamily b, polypeptide 1	Rattus norvegicus	94-100
17623886-0	2007	Inhibition of human cytochrome p450 1b1 further clarifies its role in the activation of dibenzo[a,l]pyrene in cells in culture.	dibenzo(a,l)pyrene	88-106	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	20-39
19138945-0	2008	Fetal mouse Cyp1b1 and transplacental carcinogenesis from maternal exposure to dibenzo(a,l)pyrene.	dibenzo(a,l)pyrene	79-97	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	12-18
19138945-1	2008	Dibenzo(a,l)pyrene (DBP) is among the most potent carcinogenic polycyclic aromatic hydrocarbons.	dibenzo(a,l)pyrene	0-18	D site albumin promoter binding protein	Mus musculus	20-23
17509623-0	2007	Cytotoxicity and mutagenicity of dibenzo[a,l]pyrene and (+/-)-dibenzo[a,l]pyrene-11,12-dihydrodiol in V79MZ cells co-expressing either hCYP1A1 or hCYP1B1 together with human glutathione-S-transferase A1.	dibenzo(a,l)pyrene	33-51	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	146-153
17509623-0	2007	Cytotoxicity and mutagenicity of dibenzo[a,l]pyrene and (+/-)-dibenzo[a,l]pyrene-11,12-dihydrodiol in V79MZ cells co-expressing either hCYP1A1 or hCYP1B1 together with human glutathione-S-transferase A1.	dibenzo(a,l)pyrene	33-51	glutathione S-transferase alpha 1	Homo sapiens	174-202
16581046-1	2006	We were aimed at investigating the activation of the carcinogenic polycyclic aromatic hydrocarbon (PAH) dibenzo[a,l]pyrene (DB[a,l]P) in Chinese hamster V79 cells that express single human, rat or fish cytochrome P450 (CYP) enzymes.	dibenzo(a,l)pyrene	124-132	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	219-222
16581046-4	2006	The total turnover of CYP-mediated transformation of DB[a,l]P was as follows: human CYP1B1>fish CYP1A1 approximately human CYP1A1>>rat CYP1A2>rat CYP1A1.	dibenzo(a,l)pyrene	53-61	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	22-25
16581046-4	2006	The total turnover of CYP-mediated transformation of DB[a,l]P was as follows: human CYP1B1>fish CYP1A1 approximately human CYP1A1>>rat CYP1A2>rat CYP1A1.	dibenzo(a,l)pyrene	53-61	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	84-90
16581046-4	2006	The total turnover of CYP-mediated transformation of DB[a,l]P was as follows: human CYP1B1>fish CYP1A1 approximately human CYP1A1>>rat CYP1A2>rat CYP1A1.	dibenzo(a,l)pyrene	53-61	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	99-105
16581046-4	2006	The total turnover of CYP-mediated transformation of DB[a,l]P was as follows: human CYP1B1>fish CYP1A1 approximately human CYP1A1>>rat CYP1A2>rat CYP1A1.	dibenzo(a,l)pyrene	53-61	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	126-132
16581046-4	2006	The total turnover of CYP-mediated transformation of DB[a,l]P was as follows: human CYP1B1>fish CYP1A1 approximately human CYP1A1>>rat CYP1A2>rat CYP1A1.	dibenzo(a,l)pyrene	53-61	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	144-150
16581046-4	2006	The total turnover of CYP-mediated transformation of DB[a,l]P was as follows: human CYP1B1>fish CYP1A1 approximately human CYP1A1>>rat CYP1A2>rat CYP1A1.	dibenzo(a,l)pyrene	53-61	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	126-132
16581046-8	2006	DB[a,l]P-dependent cytotoxicities (EC(50)) were found in the following order: human CYP1A1 (12 nM)>fish CYP1A1 (30 nM)>human CYP1B1 (45 nM)>>other forms.	dibenzo(a,l)pyrene	0-8	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	84-90
16581046-8	2006	DB[a,l]P-dependent cytotoxicities (EC(50)) were found in the following order: human CYP1A1 (12 nM)>fish CYP1A1 (30 nM)>human CYP1B1 (45 nM)>>other forms.	dibenzo(a,l)pyrene	0-8	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	107-113
16581046-8	2006	DB[a,l]P-dependent cytotoxicities (EC(50)) were found in the following order: human CYP1A1 (12 nM)>fish CYP1A1 (30 nM)>human CYP1B1 (45 nM)>>other forms.	dibenzo(a,l)pyrene	0-8	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	131-137
16581046-9	2006	In addition, an appreciable micronuclei formation was detected in human CYP1A1- and 1B1-expressing cells during exposure to DB[a,l]P.	dibenzo(a,l)pyrene	124-132	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	72-78
16581046-10	2006	Our study demonstrates that human CYP1A1, 1B1 and fish CYP1A1 are able to transform DB[a,l]P into genotoxic derivatives in appreciable amounts.	dibenzo(a,l)pyrene	84-92	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	34-45
16581046-10	2006	Our study demonstrates that human CYP1A1, 1B1 and fish CYP1A1 are able to transform DB[a,l]P into genotoxic derivatives in appreciable amounts.	dibenzo(a,l)pyrene	84-92	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	34-40
15833025-1	2005	The polycyclic aromatic hydrocarbons (PAHs) dibenzo[a,l]pyrene (DBP) and benzo[a]pyrene (BP) are widespread environmental contaminants and potent carcinogens.	dibenzo(a,l)pyrene	44-62	D-box binding PAR bZIP transcription factor	Homo sapiens	64-67
16005925-3	2006	We found that only strong genotoxin dibenzo[a,l]pyrene (DBalP) activated extracellular signal-regulated kinases 1 and 2 (ERK1/2) and p38 kinase, but not c-Jun N-terminal kinases (JNKs), at concentrations inducing both apoptosis and phosphorylation of p53 tumor suppressor at serine 15 residue.	dibenzo(a,l)pyrene	56-61	mitogen activated protein kinase 3	Rattus norvegicus	73-119
16005925-3	2006	We found that only strong genotoxin dibenzo[a,l]pyrene (DBalP) activated extracellular signal-regulated kinases 1 and 2 (ERK1/2) and p38 kinase, but not c-Jun N-terminal kinases (JNKs), at concentrations inducing both apoptosis and phosphorylation of p53 tumor suppressor at serine 15 residue.	dibenzo(a,l)pyrene	56-61	mitogen activated protein kinase 3	Rattus norvegicus	121-127
16005925-3	2006	We found that only strong genotoxin dibenzo[a,l]pyrene (DBalP) activated extracellular signal-regulated kinases 1 and 2 (ERK1/2) and p38 kinase, but not c-Jun N-terminal kinases (JNKs), at concentrations inducing both apoptosis and phosphorylation of p53 tumor suppressor at serine 15 residue.	dibenzo(a,l)pyrene	56-61	mitogen activated protein kinase 14	Rattus norvegicus	133-136
16005925-3	2006	We found that only strong genotoxin dibenzo[a,l]pyrene (DBalP) activated extracellular signal-regulated kinases 1 and 2 (ERK1/2) and p38 kinase, but not c-Jun N-terminal kinases (JNKs), at concentrations inducing both apoptosis and phosphorylation of p53 tumor suppressor at serine 15 residue.	dibenzo(a,l)pyrene	56-61	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	251-254
16005925-5	2006	Synthetic inhibitors of ERK1/2 activation (U0126) or p38 kinase activity (SB203580) prevented both apoptosis and induction of p53 phosphorylation by DBalP.	dibenzo(a,l)pyrene	149-154	mitogen activated protein kinase 3	Rattus norvegicus	24-30
16005925-5	2006	Synthetic inhibitors of ERK1/2 activation (U0126) or p38 kinase activity (SB203580) prevented both apoptosis and induction of p53 phosphorylation by DBalP.	dibenzo(a,l)pyrene	149-154	mitogen activated protein kinase 14	Rattus norvegicus	53-56
16005925-5	2006	Synthetic inhibitors of ERK1/2 activation (U0126) or p38 kinase activity (SB203580) prevented both apoptosis and induction of p53 phosphorylation by DBalP.	dibenzo(a,l)pyrene	149-154	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	126-129
16005925-7	2006	Taken together, our data suggest that both ERK1/2 and p38 are activated in response to DBalP and that they might be involved in regulation of cellular response to DNA damage induced by DBalP, while neither kinase is involved in the release from contact inhibition induced by PAHs.	dibenzo(a,l)pyrene	87-92	mitogen activated protein kinase 3	Rattus norvegicus	43-49
16005925-7	2006	Taken together, our data suggest that both ERK1/2 and p38 are activated in response to DBalP and that they might be involved in regulation of cellular response to DNA damage induced by DBalP, while neither kinase is involved in the release from contact inhibition induced by PAHs.	dibenzo(a,l)pyrene	87-92	mitogen activated protein kinase 14	Rattus norvegicus	54-57
16005925-7	2006	Taken together, our data suggest that both ERK1/2 and p38 are activated in response to DBalP and that they might be involved in regulation of cellular response to DNA damage induced by DBalP, while neither kinase is involved in the release from contact inhibition induced by PAHs.	dibenzo(a,l)pyrene	185-190	mitogen activated protein kinase 3	Rattus norvegicus	43-49
16005925-7	2006	Taken together, our data suggest that both ERK1/2 and p38 are activated in response to DBalP and that they might be involved in regulation of cellular response to DNA damage induced by DBalP, while neither kinase is involved in the release from contact inhibition induced by PAHs.	dibenzo(a,l)pyrene	185-190	mitogen activated protein kinase 14	Rattus norvegicus	54-57
16117800-0	2005	Harvey-ras gene expression and epidermal cell proliferation in dibenzo[a,l]pyrene-treated early preneoplastic SENCAR mouse skin.	dibenzo(a,l)pyrene	63-81	Harvey rat sarcoma virus oncogene	Mus musculus	0-10
16117800-3	2005	We have investigated DB[a,l]P-treated mouse skin (12 h-7 d) for further evidence of H-ras expression and epidermal cell proliferation.	dibenzo(a,l)pyrene	21-29	Harvey rat sarcoma virus oncogene	Mus musculus	84-89
16424006-0	2006	In utero exposure of mice to dibenzo[a,l]pyrene produces lymphoma in the offspring: role of the aryl hydrocarbon receptor.	dibenzo(a,l)pyrene	29-47	aryl-hydrocarbon receptor	Mus musculus	96-121
16424006-2	2006	A polycyclic aromatic hydrocarbon (PAH), dibenzo[a,l]pyrene (DBP), was given to pregnant mice (15 mg/kg body weight, gavage) on gestation day 17.	dibenzo(a,l)pyrene	41-59	D site albumin promoter binding protein	Mus musculus	61-64
16051029-2	2005	To date, dibenzo[a,l]pyrene (DBP) has been found to be the strongest tumor-initiating PAH ever tested in rodent skin and mammary tumor models.	dibenzo(a,l)pyrene	9-27	D site albumin promoter binding protein	Mus musculus	29-32
14720319-6	2004	In CYP1B1 gene-knockout mice treated with 7,12-dimethylbenz[a]anthracene and dibenzo[a,l]pyrene, decreased rates of tumor formation were observed, when compared to wild-type mice.	dibenzo(a,l)pyrene	77-95	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	3-9
15352028-0	2004	Dibenzo[A,L]pyrene-induced genotoxic and carcinogenic responses are dramatically suppressed in aryl hydrocarbon receptor-deficient mice.	dibenzo(a,l)pyrene	0-18	aryl-hydrocarbon receptor	Mus musculus	95-120
15223354-1	2004	The hexacyclic aromatic hydrocarbon dibenzo[def,p]chrysene, better known as dibenzo[a,l]pyrene (DBP) in the field of chemical carcinogenesis, is present in the environment as a combustion product of organic matter.	dibenzo(a,l)pyrene	76-94	D site albumin promoter binding protein	Mus musculus	96-99
15492252-4	2004	DB[a,l]P is activated to fjord region (+)-syn and (-)-anti-11,12-dihydroxy-13,14-epoxy-11,12,13,14-tetrahydrodibenzo[a,l]pyrene (DB[a,l]PDE) metabolites.	dibenzo(a,l)pyrene	0-8	joined toes	Mus musculus	42-45
12067250-1	2002	In this study, human glutathione transferases (GSTs) of alpha class have been assayed with the ultimate carcinogenic (-)-anti- and (+)-syn-diol epoxides (DEs) derived from the nonplanar dibenzo[a,l]pyrene (DBPDE) and the (+)-anti-diol epoxide of the planar benzo[a]pyrene [(+)-anti-BPDE] in the presence of glutathione (GSH).	dibenzo(a,l)pyrene	186-204	glutathione S-transferase alpha 1	Homo sapiens	47-51
12230405-0	2002	Cytochrome P450 1B1 determines susceptibility to dibenzo[a,l]pyrene-induced tumor formation.	dibenzo(a,l)pyrene	49-67	cytochrome P450, family 1, subfamily b, polypeptide 1	Mus musculus	0-19
14644359-5	2003	The expression of hsp 32 and hsp70 was studied in human diploid lung fibroblasts (HEL cells) and human monocytic leukaemia cells (THP-1 cells) incubated in vitro with different concentrations of dibenzo[a,l]pyrene (DB[a,l]P), 1-nitropyrene, (NP), 4-aminobiphenyl (ABP), ACN and EOM for different periods of time.	dibenzo(a,l)pyrene	195-213	heme oxygenase 1	Homo sapiens	18-24
12605383-0	2003	Mutations induced by (-)-anti-11R,12S-dihydrodiol 13S,14R-epoxide of dibenzo[a,l]pyrene in the coding region of the hypoxanthine phosphoribosyltransferase (Hprt) gene in Chinese hamster V79 cells.	dibenzo(a,l)pyrene	69-87	hypoxanthine-guanine phosphoribosyltransferase	Cricetulus griseus	116-154
12605383-0	2003	Mutations induced by (-)-anti-11R,12S-dihydrodiol 13S,14R-epoxide of dibenzo[a,l]pyrene in the coding region of the hypoxanthine phosphoribosyltransferase (Hprt) gene in Chinese hamster V79 cells.	dibenzo(a,l)pyrene	69-87	hypoxanthine-guanine phosphoribosyltransferase	Cricetulus griseus	156-160
11087892-0	2000	Evidence that error-prone DNA repair converts dibenzo[a,l]pyrene-induced depurinating lesions into mutations: formation, clonal proliferation and regression of initiated cells carrying H-ras oncogene mutations in early preneoplasia.	dibenzo(a,l)pyrene	46-64	Harvey rat sarcoma virus oncogene	Mus musculus	185-190
11753677-1	2001	Treatment of SENCAR mouse skin with dibenzo[a,l]pyrene results in abundant formation of abasic sites that undergo error-prone excision repair, forming oncogenic H-ras mutations in the early preneoplastic period.	dibenzo(a,l)pyrene	36-54	Harvey rat sarcoma virus oncogene	Mus musculus	161-166
11087892-2	2000	Mice treated on the dorsal skin with the potent polycyclic aromatic hydrocarbon (PAH) carcinogen dibenzo[a,l]pyrene (DB[a,l]P) form papillomas carrying the H-ras codon 61 (CAA to CTA) mutations.	dibenzo(a,l)pyrene	97-115	Harvey rat sarcoma virus oncogene	Mus musculus	156-161
10837018-7	2000	Under the same exposure and chromatographic conditions, DNA adducts of deoxyadenosine and deoxyguanosine derived from the fjord region anti-DB[a,l]P-11,12-diol-13,14-epoxide and syn-DB[a,l]P-11,12-diol-13,14-epoxide were observed in the DNA of DB[a,l]P-treated cells.	dibenzo(a,l)pyrene	140-148	joined toes	Mus musculus	178-181
10207125-1	1999	Metabolic activation of the strongly carcinogenic polycyclic aromatic hydrocarbon (PAH) dibenzo[a,l]pyrene (DB[a,l]P) and its trans-8,9-dihydrodiol (trans-8,9-diol) catalyzed by human cytochromes P450 (P450) 1A1 and 1B1 was investigated.	dibenzo(a,l)pyrene	108-116	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	184-219
10357803-1	1999	Dibenzo[a,l]pyrene (DBP), an environmentally significant polycyclic aromatic hydrocarbon (PAH), is one of the most potent carcinogens with greater carcinogenicity in rodent mammary glands and skin than 7,12-dimethylbenz[a]anthracene or benzo[a]pyrene, respectively.	dibenzo(a,l)pyrene	0-18	D-box binding PAR bZIP transcription factor	Rattus norvegicus	20-23
10334204-0	1999	The level of DNA modification by (+)-syn-(11S,12R,13S,14R)- and (-)-anti-(11R,12S,13S,14R)-dihydrodiol epoxides of dibenzo[a,l]pyrene determined the effect on the proteins p53 and p21WAF1 in the human mammary carcinoma cell line MCF-7.	dibenzo(a,l)pyrene	115-133	tumor protein p53	Homo sapiens	172-175
10207125-0	1999	Metabolic activation of dibenzo[a,l]pyrene by human cytochrome P450 1A1 and P450 1B1 expressed in V79 Chinese hamster cells.	dibenzo(a,l)pyrene	24-42	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	52-71
10207125-0	1999	Metabolic activation of dibenzo[a,l]pyrene by human cytochrome P450 1A1 and P450 1B1 expressed in V79 Chinese hamster cells.	dibenzo(a,l)pyrene	24-42	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	76-84
10506751-0	1999	A quantitative comparison of dibenzo[a,l]pyrene-DNA adduct formation by recombinant human cytochrome P450 microsomes.	dibenzo(a,l)pyrene	29-47	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	90-105
10506751-1	1999	Dibenzo[a,l]pyrene (DB[a,l]P), an extremely potent environmental carcinogen, is metabolically activated in mammalian cells and microsomes through the fjord-region dihydrodiol, trans-DB[a,l]P-11, 12-diol, to syn- and anti-DB[a,l]P-11,12-diol-13,14-epoxides (syn- and anti-DB[a,l]PDEs).	dibenzo(a,l)pyrene	0-18	synemin	Homo sapiens	207-210
10506751-1	1999	Dibenzo[a,l]pyrene (DB[a,l]P), an extremely potent environmental carcinogen, is metabolically activated in mammalian cells and microsomes through the fjord-region dihydrodiol, trans-DB[a,l]P-11, 12-diol, to syn- and anti-DB[a,l]P-11,12-diol-13,14-epoxides (syn- and anti-DB[a,l]PDEs).	dibenzo(a,l)pyrene	0-18	synemin	Homo sapiens	257-260
10506751-1	1999	Dibenzo[a,l]pyrene (DB[a,l]P), an extremely potent environmental carcinogen, is metabolically activated in mammalian cells and microsomes through the fjord-region dihydrodiol, trans-DB[a,l]P-11, 12-diol, to syn- and anti-DB[a,l]P-11,12-diol-13,14-epoxides (syn- and anti-DB[a,l]PDEs).	dibenzo(a,l)pyrene	20-28	synemin	Homo sapiens	207-210
10506751-1	1999	Dibenzo[a,l]pyrene (DB[a,l]P), an extremely potent environmental carcinogen, is metabolically activated in mammalian cells and microsomes through the fjord-region dihydrodiol, trans-DB[a,l]P-11, 12-diol, to syn- and anti-DB[a,l]P-11,12-diol-13,14-epoxides (syn- and anti-DB[a,l]PDEs).	dibenzo(a,l)pyrene	20-28	synemin	Homo sapiens	257-260
10197604-0	1999	Comparison of cytochrome P450- and peroxidase-dependent metabolic activation of the potent carcinogen dibenzo[a,l]pyrene in human cell lines: formation of stable DNA adducts and absence of a detectable increase in apurinic sites.	dibenzo(a,l)pyrene	102-120	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	14-45
9855012-6	1998	To evaluate the influence of sterical crowding in the substrate on the activity of GSTP-1, the study was extended to the strongly mutagenic fjord-region (-)-anti-DEs of benzo[c]phenanthrene and dibenzo[a,l]pyrene.	dibenzo(a,l)pyrene	194-212	glutathione S-transferase P 1	Cricetulus griseus	83-89
9855012-9	1998	Interestingly, the (-)-anti-DEs of benzo[c]phenanthrene and dibenzo[a,l]pyrene were efficiently detoxified by GSTP-1-1 in the constructed cell line (reduction of mutagenicity by 66 and 64%).	dibenzo(a,l)pyrene	60-78	glutathione S-transferase P 1	Cricetulus griseus	110-118
9600699-2	1998	In this study, we have employed a microsome-mediated test system to study the effect of several suspected chemopreventive agents on the DNA adduct formation capacity of the potent mammary carcinogen, dibenzo[a,l]pyrene (DBP).	dibenzo(a,l)pyrene	200-218	D-box binding PAR bZIP transcription factor	Rattus norvegicus	220-223
9671400-0	1998	Detection of dibenzo[a,l]pyrene-induced H-ras codon 61 mutant genes in preneoplastic SENCAR mouse skin using a new PCR-RFLP method.	dibenzo(a,l)pyrene	13-31	Harvey rat sarcoma virus oncogene	Mus musculus	40-45
9671400-2	1998	Papillomas induced by the most carcinogenic environmental polycyclic aromatic hydrocarbon (PAH), dibenzo[a,l]pyrene (DB[a,l]P), in SENCAR mouse skin contain a specific H-ras codon 61 (CAA-->CTA) mutation.	dibenzo(a,l)pyrene	97-115	Harvey rat sarcoma virus oncogene	Mus musculus	168-173
9671400-2	1998	Papillomas induced by the most carcinogenic environmental polycyclic aromatic hydrocarbon (PAH), dibenzo[a,l]pyrene (DB[a,l]P), in SENCAR mouse skin contain a specific H-ras codon 61 (CAA-->CTA) mutation.	dibenzo(a,l)pyrene	117-125	Harvey rat sarcoma virus oncogene	Mus musculus	168-173
9625737-0	1998	Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster cells and metabolically catalyzed DNA adduct formation of dibenzo[a,l]pyrene.	dibenzo(a,l)pyrene	128-146	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	27-46
9625737-14	1998	These results indicate that human P450 1B1 and P450 1A1 differ in their regio- and stereochemical selectivity of activation of DB[a,l]P with P450 1B1 forming a higher proportion of the highly carcinogenic (-)-anti-(11R, 12S,13S,14R)-DB[a,l]PDE metabolite.	dibenzo(a,l)pyrene	127-135	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	34-55
9625737-14	1998	These results indicate that human P450 1B1 and P450 1A1 differ in their regio- and stereochemical selectivity of activation of DB[a,l]P with P450 1B1 forming a higher proportion of the highly carcinogenic (-)-anti-(11R, 12S,13S,14R)-DB[a,l]PDE metabolite.	dibenzo(a,l)pyrene	127-135	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	34-42
9364006-8	1997	DB[a,l]P-DNA adducts in lung tissue were derived from both anti- and syn-11,12-dihydroxy-13,14-epoxy- 11,12,13,14-tetrahydrodibenzo[a,l]pyrene (DB[a,l]PDE) and both deoxyadenosine (dAdo) and deoxyguanosine (dGuo) residues in DNA as revealed by cochromatography.	dibenzo(a,l)pyrene	0-8	ado	Drosophila melanogaster	181-185
9364012-1	1997	Dibenzo[a,l]pyrene (DBP) is one of the most potent bacterial mutagen and mammary carcinogens.	dibenzo(a,l)pyrene	0-18	D-box binding PAR bZIP transcription factor	Rattus norvegicus	20-23
9208175-1	1997	An understanding of the conformational behavior of the stereoisomeric tetrols at the 11,12,13,14-positions of dibenzo[a,l]pyrene (DB[a,l]P) is essential for the spectroscopic identification of DNA adducts derived from the biologically highly active fjord region syn- and anti-DB[a,l]P-11,12-diol 13,14-epoxides.	dibenzo(a,l)pyrene	110-128	synemin	Homo sapiens	262-265
9288883-1	1997	Dibenzo[a,l]pyrene (DBP) has recently emerged as a potent environmental carcinogen having greater carcinogenicity in the rat mammary epithelial glands than 7,12-dimethylbenz[a]anthracene (DMBA), previously considered to be the most potent mammary carcinogen and benzo[a]pyrene (BP), a ubiquitous environmental carcinogen.	dibenzo(a,l)pyrene	0-18	D-box binding PAR bZIP transcription factor	Rattus norvegicus	20-23
8625498-1	1996	One of the major DNA adducts from the extremely potent aromatic carcinogen dibenzo[a,l]pyrene (DB[a,l]P) is the depurinating adduct syn-DB[a,l]P diolepoxide-14-N7Ade.	dibenzo(a,l)pyrene	75-93	synemin	Homo sapiens	132-135
8968059-2	1996	Of all human P450s, 1A1 was the most active in the metabolism of DB[a,l]P (310 pmol/min, nmol P450) and had 5-23-fold higher catalytic activity than other P450s examined.	dibenzo(a,l)pyrene	65-73	solute carrier family 45 member 2	Homo sapiens	20-23
8625498-1	1996	One of the major DNA adducts from the extremely potent aromatic carcinogen dibenzo[a,l]pyrene (DB[a,l]P) is the depurinating adduct syn-DB[a,l]P diolepoxide-14-N7Ade.	dibenzo(a,l)pyrene	95-103	synemin	Homo sapiens	132-135
8199298-2	1994	This paper describes the synthesis of potential ultimate carcinogens of DB[a,l]P: anti- and syn-11,12-dihydroxy-13,14-epoxy-11,12,13,14- tetrahydroDB[a,l]P (DB-[a,l]P-11,12-diol-13,14-epoxides).	dibenzo(a,l)pyrene	72-80	synemin	Homo sapiens	25-28
7955091-0	1994	Synthesis and tumor-initiating activity in mouse skin of dibenzo[a,l]pyrene syn- and anti-fjord-region diolepoxides.	dibenzo(a,l)pyrene	57-75	joined toes	Mus musculus	76-79
8374056-1	1993	Because dibenzo[a,l]pyrene (DBP) is the most potent known carcinogenic aromatic hydrocarbon, reference adducts formed by reaction of deoxyribonucleosides with electrophilic intermediates of DBP are essential for identifying the structures of adducts formed in biological systems.	dibenzo(a,l)pyrene	8-26	D-box binding PAR bZIP transcription factor	Homo sapiens	28-31
8374056-1	1993	Because dibenzo[a,l]pyrene (DBP) is the most potent known carcinogenic aromatic hydrocarbon, reference adducts formed by reaction of deoxyribonucleosides with electrophilic intermediates of DBP are essential for identifying the structures of adducts formed in biological systems.	dibenzo(a,l)pyrene	8-26	D-box binding PAR bZIP transcription factor	Homo sapiens	190-193