PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
21112944-2	2011	PGP formation is a multistep process involving neutrophils, metalloproteinases (MMPs), and prolyl endopeptidase (PE).	pgp	0-3	matrix metallopeptidase 8	Mus musculus	80-84
21112944-2	2011	PGP formation is a multistep process involving neutrophils, metalloproteinases (MMPs), and prolyl endopeptidase (PE).	pgp	0-3	prolyl endopeptidase	Mus musculus	91-111
21112944-2	2011	PGP formation is a multistep process involving neutrophils, metalloproteinases (MMPs), and prolyl endopeptidase (PE).	pgp	0-3	prolyl endopeptidase	Mus musculus	113-115
21112944-7	2011	Additionally, we investigated the effect of the peptide L-arginine-threonine-arginine (RTR), which binds to PGP sequences, on the smoke-induced neutrophil influx in the lung after 5 days of smoke exposure.	pgp	108-111	nuclear receptor subfamily 6, group A, member 1	Mus musculus	87-90
21112944-13	2011	In the present murine model of cigarette smoke-induced lung emphysema, it is demonstrated for the first time that all relevant components (neutrophils, MMP-8, MMP-9, PE) involved in PGP formation from collagen are upregulated in the airways.	pgp	182-185	matrix metallopeptidase 8	Mus musculus	152-157
21112944-13	2011	In the present murine model of cigarette smoke-induced lung emphysema, it is demonstrated for the first time that all relevant components (neutrophils, MMP-8, MMP-9, PE) involved in PGP formation from collagen are upregulated in the airways.	pgp	182-185	matrix metallopeptidase 9	Mus musculus	159-164
21112944-13	2011	In the present murine model of cigarette smoke-induced lung emphysema, it is demonstrated for the first time that all relevant components (neutrophils, MMP-8, MMP-9, PE) involved in PGP formation from collagen are upregulated in the airways.	pgp	182-185	prolyl endopeptidase	Mus musculus	166-168
21112944-14	2011	Together with MMPs, PE may play an important role in the formation of PGP and thus in the pathophysiology of lung emphysema.	pgp	70-73	matrix metallopeptidase 8	Mus musculus	14-18
21112944-14	2011	Together with MMPs, PE may play an important role in the formation of PGP and thus in the pathophysiology of lung emphysema.	pgp	70-73	prolyl endopeptidase	Mus musculus	20-22
20691773-10	2010	PGP EtOAc extract increased a sub-G1 cell population through inducing p53/p21 and activated caspase-8 protein expression in B16F10 cells.	pgp	0-3	transformation related protein 53, pseudogene	Mus musculus	70-73
20691773-10	2010	PGP EtOAc extract increased a sub-G1 cell population through inducing p53/p21 and activated caspase-8 protein expression in B16F10 cells.	pgp	0-3	caspase 8	Mus musculus	92-101
19875179-2	2009	We have recently demonstrated that PE, in concert with MMP"s, can generate PGP (proline-glycine-proline), a novel, neutrophil chemoattractant, from collagen.	pgp	75-78	prolyl endopeptidase	Homo sapiens	35-37
20813919-2	2010	LTA(4)H also possesses aminopeptidase activity with unknown substrate and physiological importance; we identified the neutrophil chemoattractant proline-glycine-proline (PGP) as this physiological substrate.	pgp	170-173	leukotriene A4 hydrolase	Homo sapiens	0-7
20813919-5	2010	In contrast, cigarette smoke, a major risk factor for the development of COPD, selectively inhibited LTA(4)H aminopeptidase activity, which led to the accumulation of PGP and neutrophils.	pgp	167-170	leukotriene A4 hydrolase	Homo sapiens	101-108
19875179-3	2009	In this study, we demonstrate that human peripheral blood neutrophils contain PE, which is constitutively active, and can generate PGP de novo from collagen after activation with LPS.	pgp	131-134	prolyl endopeptidase	Homo sapiens	78-80
18658107-11	2008	Intratracheal administration of purified HMGB1 induced neutrophil influx into the airways of mice and promoted the release of PGP.	pgp	126-129	high mobility group box 1	Mus musculus	41-46
19299743-6	2009	The enzymes responsible for generating PGP, matrix metalloproteases 8 and -9 and prolyl endopeptidase, are also elevated in these samples.	pgp	39-42	prolyl endopeptidase	Homo sapiens	81-101
19299743-8	2009	Using specific neutralizing Abs to both IL-8 and PGP, we demonstrate that PGP is a prominent neutrophil chemoattractant found in BAL fluid from individuals at the time of diagnosis of BOS.	pgp	74-77	C-X-C motif chemokine ligand 8	Homo sapiens	40-44
18658107-12	2008	PGP was also elevated in Scnn1b-Tg mice and CF serum.	pgp	0-3	sodium channel, nonvoltage-gated 1 beta	Mus musculus	25-31
18787070-4	2008	Here, we have analysed the importance of the functional interaction between PIN- and PGP-dependent auxin transport in development.	pgp	85-88	dynein light chain LC8-type 1	Homo sapiens	76-80
18787070-8	2008	We propose a model in which PGP-mediated efflux controls auxin levels in auxin channel-forming cells and, thus, auxin availability for PIN-dependent vectorial auxin movement.	pgp	28-31	dynein light chain LC8-type 1	Homo sapiens	135-138
17355820-9	2007	Compared with the control group the concentration of CTnI in the PGP group was significantly lower at 6 and 24 hours (P < 0.01).	pgp	65-68	troponin I3, cardiac type	Homo sapiens	53-57
18390751-5	2008	We describe the specific multistep proteolytic pathway involved in PGP generation from collagen, involving matrix metalloproteases 8 and 9 and prolyl endopeptidase, a serine protease for which we identify a novel role in inflammation.	pgp	67-70	prolyl endopeptidase	Homo sapiens	107-163
18390751-5	2008	We describe the specific multistep proteolytic pathway involved in PGP generation from collagen, involving matrix metalloproteases 8 and 9 and prolyl endopeptidase, a serine protease for which we identify a novel role in inflammation.	pgp	67-70	coagulation factor II, thrombin	Homo sapiens	167-182
11447173-4	2001	PGP induced a high level of interleukin-8 production at doses of 100 ng/ml and higher in OCT-treated THP-1 cells compared with Salmonella LPS, and the production was significantly inhibited by anti-CD14 and anti-TLR2 but not anti-TLR4 antibodies.	pgp	0-3	C-X-C motif chemokine ligand 8	Homo sapiens	28-41
16887800-2	2006	Overlapping phenotypes of pgp1/pgp19 and twd1 mutant plants suggested a positive regulatory role of TWD1 in PGP-mediated export of the plant hormone auxin, which controls plant development.	pgp	108-111	phosphatidylglycerolphosphate synthase 1	Arabidopsis thaliana	26-30
16887800-2	2006	Overlapping phenotypes of pgp1/pgp19 and twd1 mutant plants suggested a positive regulatory role of TWD1 in PGP-mediated export of the plant hormone auxin, which controls plant development.	pgp	108-111	ATP binding cassette subfamily B19	Arabidopsis thaliana	31-36
16887800-2	2006	Overlapping phenotypes of pgp1/pgp19 and twd1 mutant plants suggested a positive regulatory role of TWD1 in PGP-mediated export of the plant hormone auxin, which controls plant development.	pgp	108-111	FKBP-type peptidyl-prolyl cis-trans isomerase family protein	Arabidopsis thaliana	41-45
16887800-2	2006	Overlapping phenotypes of pgp1/pgp19 and twd1 mutant plants suggested a positive regulatory role of TWD1 in PGP-mediated export of the plant hormone auxin, which controls plant development.	pgp	108-111	FKBP-type peptidyl-prolyl cis-trans isomerase family protein	Arabidopsis thaliana	100-104
16887800-3	2006	Here, we provide evidence at the cellular and plant levels that TWD1 controls PGP-mediated auxin transport.	pgp	78-81	FKBP-type peptidyl-prolyl cis-trans isomerase family protein	Arabidopsis thaliana	64-68
15958635-3	2005	We found that gene-transfected antigen-presenting cells efficiently expand functionally competent PGP-specific CD4 and CD8 T cells.	pgp	98-101	CD4 molecule	Homo sapiens	111-114
15958635-3	2005	We found that gene-transfected antigen-presenting cells efficiently expand functionally competent PGP-specific CD4 and CD8 T cells.	pgp	98-101	CD8a molecule	Homo sapiens	119-122
11447173-4	2001	PGP induced a high level of interleukin-8 production at doses of 100 ng/ml and higher in OCT-treated THP-1 cells compared with Salmonella LPS, and the production was significantly inhibited by anti-CD14 and anti-TLR2 but not anti-TLR4 antibodies.	pgp	0-3	CD14 molecule	Homo sapiens	198-202
11447173-4	2001	PGP induced a high level of interleukin-8 production at doses of 100 ng/ml and higher in OCT-treated THP-1 cells compared with Salmonella LPS, and the production was significantly inhibited by anti-CD14 and anti-TLR2 but not anti-TLR4 antibodies.	pgp	0-3	toll like receptor 2	Homo sapiens	212-216
11447173-4	2001	PGP induced a high level of interleukin-8 production at doses of 100 ng/ml and higher in OCT-treated THP-1 cells compared with Salmonella LPS, and the production was significantly inhibited by anti-CD14 and anti-TLR2 but not anti-TLR4 antibodies.	pgp	0-3	toll like receptor 4	Homo sapiens	230-234
11447173-7	2001	These results indicate that PGP activates monocytic cells in a CD14- and TLR2-dependent manner.	pgp	28-31	CD14 molecule	Homo sapiens	63-67
11447173-7	2001	These results indicate that PGP activates monocytic cells in a CD14- and TLR2-dependent manner.	pgp	28-31	toll like receptor 2	Homo sapiens	73-77
31176670-2	2020	PGP is normally then degraded by leukotriene A4 hydrolase (LTA4H) to limit inflammation and remodelling.	pgp	0-3	leukotriene A4 hydrolase	Homo sapiens	59-64
32309365-12	2020	Further mechanistic investigations indicated that the protective effect of PREP disruption on liver inflammation was associated with the suppressed production of matrix metalloproteinases (MMPs) and proline-glycine-proline (PGP) and the inhibition of neutrophil infiltration.	pgp	224-227	prolyl endopeptidase	Mus musculus	75-79
11583372-7	2001	A positive correlation was found between PGP and ClCr (r = 0.30; p < 0.01).	pgp	41-44	chymotrypsin C	Homo sapiens	49-53
10937800-2	2000	Tripeptide PGP after single intravenous (0.2, 1.0 and 1.5 mg/kg) or intranasal (0.5 mg/ kg) administration increased (P < 0.05) total fibrinolytic and fibrin depolymerizating (FDA) activities, and tissue plasminogen activator levels (t-PA), and decreased the plasmin inhibitors (PI) and activated factor XIII (factor XIIIa) levels in blood plasma.	pgp	11-14	plasminogen activator, tissue type	Rattus norvegicus	200-235
10937800-2	2000	Tripeptide PGP after single intravenous (0.2, 1.0 and 1.5 mg/kg) or intranasal (0.5 mg/ kg) administration increased (P < 0.05) total fibrinolytic and fibrin depolymerizating (FDA) activities, and tissue plasminogen activator levels (t-PA), and decreased the plasmin inhibitors (PI) and activated factor XIII (factor XIIIa) levels in blood plasma.	pgp	11-14	plasminogen activator, tissue type	Rattus norvegicus	237-241
10209085-14	1999	Insofar as an elevated level of E-selectin in peripheral blood reflects vascular endothelial activation, the data are consistent with the notion that pulmonary endothelial activation is required, in addition to granulocyte activation and an expanded PGP, for granulocyte migration into lung parenchyma and, therefore, for lung injury to occur.	pgp	250-253	selectin E	Homo sapiens	32-42
31176670-1	2020	BACKGROUND: Proline-glycine-proline (PGP) is a bioactive fragment of collagen generated by the action of matrix metalloproteinase-9 (MMP-9) and prolylendopeptidase (PE), and capable of eliciting neutrophil chemotaxis and epithelial remodelling.	pgp	37-40	matrix metallopeptidase 9	Homo sapiens	105-131
31176670-1	2020	BACKGROUND: Proline-glycine-proline (PGP) is a bioactive fragment of collagen generated by the action of matrix metalloproteinase-9 (MMP-9) and prolylendopeptidase (PE), and capable of eliciting neutrophil chemotaxis and epithelial remodelling.	pgp	37-40	matrix metallopeptidase 9	Homo sapiens	133-138
31176670-2	2020	PGP is normally then degraded by leukotriene A4 hydrolase (LTA4H) to limit inflammation and remodelling.	pgp	0-3	leukotriene A4 hydrolase	Homo sapiens	33-57
31176670-7	2020	BAL levels of MMP-9 and PE were elevated in older children with CF relative to CF newborns and non-CF controls, correlating with airway neutrophilia and supportive of PGP generation.	pgp	167-170	matrix metallopeptidase 9	Homo sapiens	14-19
31176670-8	2020	Furthermore, despite extracellular LTA4H commonly being greatly elevated concomitantly with inflammation to promote PGP degradation, this was not the case in CF children, potentially owing to degradation by neutrophil elastase.	pgp	116-119	leukotriene A4 hydrolase	Homo sapiens	35-40
30958968-2	2019	The neutrophil chemoattractant proline-glycine-proline (PGP) and its more potent acetylated form (acPGP) have been found to be elevated in COPD patients and act via CXCR2.	pgp	56-59	C-X-C motif chemokine receptor 2	Homo sapiens	165-170
30958968-4	2019	The PGP neutralizing peptide L-arginine-threonine-arginine (RTR) was used first in a 6-week model of cigarette smoke exposure, where it attenuated lung inflammation.	pgp	4-7	nuclear receptor subfamily 6, group A, member 1	Mus musculus	60-63
26717512-4	2016	One promising field focuses on the central role of the neutrophil and the tripeptide matrikine proline-glycine-proline (PGP) in a subset of COPD patients.	pgp	120-123	COPD	Homo sapiens	140-144
28498807-8	2017	In the THC8307 cell line, PKM2 and GLS1 can accelerate malignant behaviors, increase oxaliplatin-resistance, upregulate Pgp expression, and inhibit cell apoptosis.	pgp	120-123	pyruvate kinase M1/2	Homo sapiens	26-30
28498807-8	2017	In the THC8307 cell line, PKM2 and GLS1 can accelerate malignant behaviors, increase oxaliplatin-resistance, upregulate Pgp expression, and inhibit cell apoptosis.	pgp	120-123	glutaminase	Homo sapiens	35-39
28498807-9	2017	Contrastingly in the THC8307/Oxa cell line, knockdown of PKM2/GLS1 expression can restrain malignant behaviors, reestablish oxaliplatin-sensitivity, downregulate Pgp expression, and induce cell apoptosis.	pgp	162-165	pyruvate kinase M1/2	Homo sapiens	57-61
28498807-9	2017	Contrastingly in the THC8307/Oxa cell line, knockdown of PKM2/GLS1 expression can restrain malignant behaviors, reestablish oxaliplatin-sensitivity, downregulate Pgp expression, and induce cell apoptosis.	pgp	162-165	glutaminase	Homo sapiens	62-66
29202450-1	2017	The neutrophil chemoattractant proline-glycine-proline (PGP) is generated from collagen by matrix metalloproteinase-8/9 (MMP-8/9) and prolyl endopeptidase (PE), and it is concomitantly degraded by extracellular leukotriene A4 hydrolase (LTA4H) to limit neutrophilia.	pgp	56-59	matrix metallopeptidase 8	Homo sapiens	91-119
29202450-1	2017	The neutrophil chemoattractant proline-glycine-proline (PGP) is generated from collagen by matrix metalloproteinase-8/9 (MMP-8/9) and prolyl endopeptidase (PE), and it is concomitantly degraded by extracellular leukotriene A4 hydrolase (LTA4H) to limit neutrophilia.	pgp	56-59	matrix metallopeptidase 8	Homo sapiens	121-128
29202450-1	2017	The neutrophil chemoattractant proline-glycine-proline (PGP) is generated from collagen by matrix metalloproteinase-8/9 (MMP-8/9) and prolyl endopeptidase (PE), and it is concomitantly degraded by extracellular leukotriene A4 hydrolase (LTA4H) to limit neutrophilia.	pgp	56-59	prolyl endopeptidase	Homo sapiens	134-154
29202450-1	2017	The neutrophil chemoattractant proline-glycine-proline (PGP) is generated from collagen by matrix metalloproteinase-8/9 (MMP-8/9) and prolyl endopeptidase (PE), and it is concomitantly degraded by extracellular leukotriene A4 hydrolase (LTA4H) to limit neutrophilia.	pgp	56-59	prolyl endopeptidase	Homo sapiens	156-158
29202450-1	2017	The neutrophil chemoattractant proline-glycine-proline (PGP) is generated from collagen by matrix metalloproteinase-8/9 (MMP-8/9) and prolyl endopeptidase (PE), and it is concomitantly degraded by extracellular leukotriene A4 hydrolase (LTA4H) to limit neutrophilia.	pgp	56-59	leukotriene A4 hydrolase	Homo sapiens	211-235
29202450-1	2017	The neutrophil chemoattractant proline-glycine-proline (PGP) is generated from collagen by matrix metalloproteinase-8/9 (MMP-8/9) and prolyl endopeptidase (PE), and it is concomitantly degraded by extracellular leukotriene A4 hydrolase (LTA4H) to limit neutrophilia.	pgp	56-59	leukotriene A4 hydrolase	Homo sapiens	237-242
29202450-2	2017	Components of cigarette smoke can acetylate PGP, yielding a species (AcPGP) that is resistant to LTA4H-mediated degradation and can, thus, support a sustained neutrophilia.	pgp	44-47	leukotriene A4 hydrolase	Homo sapiens	97-102
29202450-3	2017	In this study, we sought to elucidate if an antiinflammatory system existed to degrade AcPGP that is analogous to the PGP-LTA4H axis.	pgp	89-92	leukotriene A4 hydrolase	Homo sapiens	122-127
27899993-8	2016	Furthermore, the 20 MP/TF-positive samples were associated with Pgp overexpression on their surface.	pgp	64-67	coagulation factor III, tissue factor	Homo sapiens	23-25
27899993-11	2016	The present study demonstrated that MPs in the blood of cancer patients promoted fibrin generation via TF/FVII-dependent pathways, thus suggesting that the evaluation of MP-TF activity may have a predictive value for Pgp-mediated MDR in various cancer types.	pgp	217-220	coagulation factor III, tissue factor	Homo sapiens	173-175
27899993-12	2016	Although further studies are required, the measurement of plasma MP-associated TF activity as a predictive biomarker may provide novel therapeutic perspectives to improve the prognosis and effectiveness of anti-cancer drugs in patients who are at a high-risk of Pgp-mediated MDR.	pgp	262-265	coagulation factor III, tissue factor	Homo sapiens	79-81
25987242-0	2016	A common polymorphism in the ABCB1 gene is associated with side effects of PGP-dependent antidepressants in a large naturalistic Dutch cohort.	pgp	75-78	ATP binding cassette subfamily B member 1	Homo sapiens	29-34
25987242-2	2016	The ABCB1 gene, encoding for PGP, and CYP2C19 gene have several variants that could influence enzyme function and thereby the effect of PGP- and 2C19-dependent antidepressants.	pgp	29-32	ATP binding cassette subfamily B member 1	Homo sapiens	4-9
25987242-2	2016	The ABCB1 gene, encoding for PGP, and CYP2C19 gene have several variants that could influence enzyme function and thereby the effect of PGP- and 2C19-dependent antidepressants.	pgp	136-139	ATP binding cassette subfamily B member 1	Homo sapiens	4-9
25987242-2	2016	The ABCB1 gene, encoding for PGP, and CYP2C19 gene have several variants that could influence enzyme function and thereby the effect of PGP- and 2C19-dependent antidepressants.	pgp	136-139	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	38-45
25987242-7	2016	The association of rs2032588 with antidepressant side effects suggests the involvement of the ABCB1 genotype in the clinical pharmacology of PGP-dependent antidepressants.	pgp	141-144	ATP binding cassette subfamily B member 1	Homo sapiens	94-99
26208604-5	2015	Meanwhile, LTA4H levels and triaminopeptidase activity declined with increasing concentrations of acrolein thereby sparing PGP from enzymatic destruction.	pgp	123-126	leukotriene A4 hydrolase	Homo sapiens	11-16
26400771-2	2015	We recently described a pathway where the matrikine and neutrophil chemoattractant proline-glycine-proline (PGP) could be degraded by the enzyme leukotriene A4 hydrolase (LTA4H).	pgp	108-111	leukotriene A4 hydrolase	Homo sapiens	145-169
26400771-2	2015	We recently described a pathway where the matrikine and neutrophil chemoattractant proline-glycine-proline (PGP) could be degraded by the enzyme leukotriene A4 hydrolase (LTA4H).	pgp	108-111	leukotriene A4 hydrolase	Homo sapiens	171-176
25636538-4	2015	Of the 20 MMPs identified, MMP-1, MMP-2, MMP-8, MMP-9, and MMP-12 have been implicated in regulating the matrikines Val-Gly-Val-Ala-Pro-Gly (elastin peptide) and proline-glycine-proline (PGP).	pgp	187-190	matrix metallopeptidase 1	Homo sapiens	10-14
25636538-4	2015	Of the 20 MMPs identified, MMP-1, MMP-2, MMP-8, MMP-9, and MMP-12 have been implicated in regulating the matrikines Val-Gly-Val-Ala-Pro-Gly (elastin peptide) and proline-glycine-proline (PGP).	pgp	187-190	matrix metallopeptidase 1	Homo sapiens	27-32
25636538-4	2015	Of the 20 MMPs identified, MMP-1, MMP-2, MMP-8, MMP-9, and MMP-12 have been implicated in regulating the matrikines Val-Gly-Val-Ala-Pro-Gly (elastin peptide) and proline-glycine-proline (PGP).	pgp	187-190	matrix metallopeptidase 2	Homo sapiens	34-39
25636538-4	2015	Of the 20 MMPs identified, MMP-1, MMP-2, MMP-8, MMP-9, and MMP-12 have been implicated in regulating the matrikines Val-Gly-Val-Ala-Pro-Gly (elastin peptide) and proline-glycine-proline (PGP).	pgp	187-190	matrix metallopeptidase 8	Homo sapiens	41-46
25636538-4	2015	Of the 20 MMPs identified, MMP-1, MMP-2, MMP-8, MMP-9, and MMP-12 have been implicated in regulating the matrikines Val-Gly-Val-Ala-Pro-Gly (elastin peptide) and proline-glycine-proline (PGP).	pgp	187-190	matrix metallopeptidase 9	Homo sapiens	48-53
25636538-4	2015	Of the 20 MMPs identified, MMP-1, MMP-2, MMP-8, MMP-9, and MMP-12 have been implicated in regulating the matrikines Val-Gly-Val-Ala-Pro-Gly (elastin peptide) and proline-glycine-proline (PGP).	pgp	187-190	matrix metallopeptidase 12	Homo sapiens	59-65
25636538-4	2015	Of the 20 MMPs identified, MMP-1, MMP-2, MMP-8, MMP-9, and MMP-12 have been implicated in regulating the matrikines Val-Gly-Val-Ala-Pro-Gly (elastin peptide) and proline-glycine-proline (PGP).	pgp	187-190	elastin	Homo sapiens	141-148
25636538-8	2015	In chronic cigarette smoke related lung disease, the PGP pathway can become a self-propagating cycle of inflammation through cigarette-smoke mediated inhibition of leukotriene A4 hydrolase, the enzyme responsible for degrading PGP and halting acute inflammation.	pgp	53-56	leukotriene A4 hydrolase	Homo sapiens	164-188
25636538-8	2015	In chronic cigarette smoke related lung disease, the PGP pathway can become a self-propagating cycle of inflammation through cigarette-smoke mediated inhibition of leukotriene A4 hydrolase, the enzyme responsible for degrading PGP and halting acute inflammation.	pgp	227-230	leukotriene A4 hydrolase	Homo sapiens	164-188
24771855-2	2014	We hypothesize that the LTA4H aminopeptidase activity alleviates neutrophilic inflammation, which contributes to cigarette smoke (CS)-induced emphysema by clearing proline-glycine-proline (PGP), a triamino acid chemokine known to induce chemotaxis of neutrophils.	pgp	189-192	leukotriene A4 hydrolase	Mus musculus	24-29
24771855-6	2014	This resulted in accumulation of PGP in the airspaces by suppressing the LTA4H aminopeptidase activity.	pgp	33-36	leukotriene A4 hydrolase	Mus musculus	73-78
24771855-7	2014	When the LTA4H aminopeptidase activity was selectively augmented by 4MDM, the levels of PGP in the bronchoalveolar lavage fluid and infiltration of neutrophils into the lungs were significantly reduced without affecting the levels of leukotriene B4.	pgp	88-91	leukotriene A4 hydrolase	Mus musculus	9-14
24874071-5	2014	Two human cohorts were used to analyze changes to the LTA4H-PGP pathway in never smokers, control smokers, COPD smokers, and COPD former smokers.	pgp	60-63	leukotriene A4 hydrolase	Mus musculus	54-59
24874071-7	2014	MEASUREMENTS AND MAIN RESULTS: Mice exposed to cigarette smoke developed emphysema with increased PGP, neutrophilic inflammation, and selective inhibition of LTA4H aminopeptidase, which ordinarily degrades PGP.	pgp	206-209	leukotriene A4 hydrolase	Mus musculus	158-163
23525573-1	2014	OBJECTIVE: Proline-glycine-proline (PGP) has been shown to have chemotactic effects on neutrophils via CXCR2 in several lung diseases.	pgp	36-39	C-X-C motif chemokine receptor 2	Homo sapiens	103-108