PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8661368-10 1996 Pulsed VT (8 to 48 hr) or cycloheximide (4 to 48 hr) exposure of CD4(+) cells enhanced supernatant levels of IL-2 but not IL-4 upon incubation for 24 hr in fresh medium. Cycloheximide 26-39 interleukin 4 Mus musculus 122-126 14500682-5 2003 Cycloheximide as well as sodium cromoglycate blocked the Der f-induced IL-4 production, indicating a de novo protein synthesis process. Cycloheximide 0-13 interleukin 4 Mus musculus 71-75 11859138-6 2002 Second, the ability of IL-4 to potentiate LPS-stimulated cytokine production appears to require new IL-4-stimulated gene expression, because it is time dependent, requires the activation of STAT6, and is blocked by the reversible protein synthesis inhibitor cycloheximide during the IL-4 pretreatment period. Cycloheximide 258-271 interleukin 4 Mus musculus 23-27 11859138-6 2002 Second, the ability of IL-4 to potentiate LPS-stimulated cytokine production appears to require new IL-4-stimulated gene expression, because it is time dependent, requires the activation of STAT6, and is blocked by the reversible protein synthesis inhibitor cycloheximide during the IL-4 pretreatment period. Cycloheximide 258-271 interleukin 4 Mus musculus 100-104 11859138-6 2002 Second, the ability of IL-4 to potentiate LPS-stimulated cytokine production appears to require new IL-4-stimulated gene expression, because it is time dependent, requires the activation of STAT6, and is blocked by the reversible protein synthesis inhibitor cycloheximide during the IL-4 pretreatment period. Cycloheximide 258-271 interleukin 4 Mus musculus 100-104 9122225-6 1997 B cells, but not T cells or mast cells, express Fig1 in response to IL-4 within 2 hr in a cycloheximide resistant manner. Cycloheximide 90-103 interleukin 4 Mus musculus 68-72 8658534-11 1996 Pulsed VT (8 to 48 hr) or cycloheximide (4 to 48 hr) exposure of CD4+ cells enhanced supernatant levels of IL-2 but not IL-4 upon incubation for 24 hr in fresh medium. Cycloheximide 26-39 interleukin 4 Mus musculus 120-124 2142529-9 1990 Effects of cyclosporine A and the protein synthesis inhibitors cycloheximide and anisomycin on IL-4 and IL-5 gene expression suggest that these genes are activated by different pathways after anti-CD3 stimulation. Cycloheximide 63-76 interleukin 4 Mus musculus 95-99 8852946-6 1996 The inhibition of PGHS-2 and cPLA2 mRNA expression by IL-4 (10 ng/ml) was present at 1 h, reached a maximum at 4 h, and persisted for 24 h. The effects were maintained in the presence of cycloheximide. Cycloheximide 187-200 interleukin 4 Mus musculus 54-58 7768303-9 1995 TGF-beta 1- and IL-4-mediated augmentation of MCP-1/JE mRNA by IL-1 alpha or IFN-gamma was partially reversed by cycloheximide (CHX), whereas potentiation of IP-10 by either modulator remained unaffected. Cycloheximide 113-126 interleukin 4 Mus musculus 16-20 7768303-9 1995 TGF-beta 1- and IL-4-mediated augmentation of MCP-1/JE mRNA by IL-1 alpha or IFN-gamma was partially reversed by cycloheximide (CHX), whereas potentiation of IP-10 by either modulator remained unaffected. Cycloheximide 128-131 interleukin 4 Mus musculus 16-20 8061119-4 1994 The data show that incubation with IL-4 results in a dose-dependent, 2-3 x increase in M-CSFr with no change in binding affinity and a maximal effect on binding at about 12 h. This increase in M-CSFr is dependent upon new, specific protein synthesis as shown by the inhibitory action of cycloheximide, and gel analysis of radiolabeled, specific protein, immunoprecipitated with anti-M-CSFr antibody. Cycloheximide 287-300 interleukin 4 Mus musculus 35-39 1531844-7 1992 Treatment of IFN-gamma/IL-2-stimulated macrophages with cycloheximide blocks the suppressive effect of IL-4, suggesting that de novo synthesis of an intermediate protein is part of the suppressive mechanism. Cycloheximide 56-69 interleukin 4 Mus musculus 103-107 2140531-5 1990 The Ia-inductive effects of both IL-4 and IgE-antigen complexes were inhibited by cycloheximide and actinomycin-D. Cycloheximide 82-95 interleukin 4 Mus musculus 33-37 2140531-6 1990 However, whereas actinomycin-D and cycloheximide blocked IL-4 induction of Fc epsilon RII expression, inhibition of transcription or protein synthesis did not abrogate the increased expression of Fc epsilon R associated with IgE-antigen complexes. Cycloheximide 35-48 interleukin 4 Mus musculus 57-61 8459105-11 1993 Addition of cycloheximide (50 micrograms/ml) inhibited formation of IL-2, IL-4 and IL-6 SFC by approximately 90%. Cycloheximide 12-25 interleukin 4 Mus musculus 74-78