PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11804937-11 2002 The effects of hCG and activin on maturational competence of oocytes could be significantly inhibited by actinomycin D (1 microg/ml) and completely blocked by cycloheximide (1 microg/ml), suggesting that the hCG and activin-induced acquisition of oocyte maturational competence involves de novo protein synthesis at both the transcriptional and translational levels. Cycloheximide 159-172 chorionic gonadotropin subunit beta 5 Homo sapiens 15-18 11804937-11 2002 The effects of hCG and activin on maturational competence of oocytes could be significantly inhibited by actinomycin D (1 microg/ml) and completely blocked by cycloheximide (1 microg/ml), suggesting that the hCG and activin-induced acquisition of oocyte maturational competence involves de novo protein synthesis at both the transcriptional and translational levels. Cycloheximide 159-172 chorionic gonadotropin subunit beta 5 Homo sapiens 208-211 9363259-10 1995 Only hCG kinetics were significantly different between tissue incubated with and without cycloheximide or iodoacetic acid. Cycloheximide 89-102 chorionic gonadotropin subunit beta 5 Homo sapiens 5-8 7989473-11 1994 Cycloheximide had no effect on basal alpha-subunit mRNA levels at 2 or 24 h. However, it inhibited at 24 h the induction of the alpha-subunit by hCG. Cycloheximide 0-13 chorionic gonadotropin subunit beta 5 Homo sapiens 145-148 7744046-5 1995 Both actinomycin D and cycloheximide blocked the hCG-induced decrease in both receptor number and mRNA levels. Cycloheximide 23-36 chorionic gonadotropin subunit beta 5 Homo sapiens 49-52 1874173-8 1991 Furthermore, cycloheximide (1 microgram/ml) markedly blocked hCG-induced P450scc mRNA expression. Cycloheximide 13-26 chorionic gonadotropin subunit beta 5 Homo sapiens 61-64 3259999-2 1988 Pretreatment with cycloheximide (Cyclo) or aminoglutethimide (Ag) prevented these effects of hCG, while Actinomycin D (Act-D) or Azastene, an inhibitor of 3-hydroxysteroid dehydrogenase, were ineffective. Cycloheximide 18-31 chorionic gonadotropin subunit beta 5 Homo sapiens 93-96 3259999-2 1988 Pretreatment with cycloheximide (Cyclo) or aminoglutethimide (Ag) prevented these effects of hCG, while Actinomycin D (Act-D) or Azastene, an inhibitor of 3-hydroxysteroid dehydrogenase, were ineffective. Cycloheximide 33-38 chorionic gonadotropin subunit beta 5 Homo sapiens 93-96